Gene 11909 (Tetrahymena)

11909

Species: Tetrahymena
Alias: 930, PreTt11909, 11909, TTHERM_00016020, 1.m00957
External Links: Tetrahymena Genome Database (TGD)
Annotation:

Classification

Group: AGC
Family: Akt
Subfamily: RSK

Sequence

Name Sequence Type Origin Length Description Download
11909.AA Protein None 394 None Fasta, JSON
11909.kin_dom Protein Kinase Domain None 266 None Fasta, JSON
11909.NA RNA None 1185 None Fasta, JSON

Protein domain

Protein domains of 11909.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Kinase 11909.AA Akt 37-302 50 4.5e-185 596.66 In-house 1-264 (264) Show / Hide 
Range on Protein: 37-302
Range on HMM: 1-264/264
Sequence Identity: 50% (137 aa)

FEFIKCIGTGSFGKVYLVKKKQTEDLY-AMKILRKDQIKNKTQLIQTKAERYILENVDSPFVVQLAYAFQSQTKLYIVMEFCQGGDIFGHMVKQPFFPEN
|.|.|..| ||||||.|||||.|...| |||.|.||.| .| |. .||.||.||.....||.|.| |.||.|.|||.||..|.||..| |. ....|.|.
FDFLKVLGKGSFGKVFLVKKKDTQKWYYAMKVLKKDYIIQKNQVEHTKTERNILQHCNHPFIVNLHYSFQTQDKLYFVMDYCNGGELFYHLQRKRRFSED

KIKFYAAEIFLALEKLHEQGIVYRD-LKPENILVSATGHIKLTDFGLSKKL-KSRDEITYSFCGTAEYMAPEIISKQGHDVASDWWSFFKYLNISKGAVL
...||.|||.||.| ||...|.||| |||||||....|||.||||||.|.  ......|..||||.||.||||....||. |.|||.       | |.|.
RARFYCAEIILAIEHLHSKNIIYRDYLKPENILMDKDGHICLTDFGLCKENIIKDHDKTKTFCGTPEYLAPEILNGNGHTKAVDWWG-------SLGCVM

YEMLHGAPPFYEKNKERMMDKLVNQDVVIK--DKYSKECQSLLRGLLTRDKTKRLGNGPEGTQEIRNHPFF
|||..|.||||......|..|  ||.| ..  |..|.||..|..|||..|..||||.||...|||..||.|
YEMMCGRPPFYNQDHHQMFKKIKNQPVKFPDKDWISPECKDLISGLLNKDPKKRLGGGPNDAQEIKRHPWF
Kinase 11909.AA AGC 37-302 34 1.3e-177 463.92 In-house 1-395 (395) Show / Hide 
Range on Protein: 37-302
Range on HMM: 1-395/395
Sequence Identity: 34% (138 aa)

FEFIKCIGTGSFGKVYLVKKK------QTEDLYAMKILRKDQ---IKNKTQLIQTKAE------------RYILENVD----------SPFVVQ-LAYAF
|||.|.||.|||||||||.||      .|...||||.|.|.    ||.| .. .|..|            | |||...          .||.|. | |.|
FEFLKVIGKGSFGKVYLVRKKDGCHKKDTGKYYAMKVLKKKHKIVIKKKNMVEHTMTEHWKQDQGYVWEERNILEKCNHTHNHPIKSHHPFIVKILHYSF

QSQTK--LYIVMEFCQ---------GG-DIFGHMV---KQPFFPENKIKFYAAE-------IFLALEKLHE-QGIVYRD-LKPENILVSATGHIKLTDFG
|....  ||.|||...         || . | |.    |.  |.|. ..|||||       | |||| ||. .||..|| |||||||  . |||||||||
QDKDHTYLYFVMEYMPRYVNDLYCGGGCELFLHLQGRRKEGRFDEERARFYAAEMQKICGCIVLALEYLHSHMGIIHRDYLKPENILLDEDGHIKLTDFG

LSKKLKSRDEI--------------------------------------------------TYSFCG--TAEYMAPEIISKQGHDVASDWWSFFKYLNIS
|.|......|.                                                  |..|||  |.|||||||.    .. | |||||      .
LCKEGMNDGEKGQQSQSNMKFHWHNKKYQKSNMDTNKCNPNNWQRNNMSQEDDTTRKKRDRTWTFCGPCTPEYMAPEIL----YGKACDWWSF------G

KGAVLYEMLHGAPPFYEKN----------KERMMDKLV------NQDVVIK----------DKYSKECQSLLRGLLTRDKTKRLGNGPE-----GTQEIR
 |...|||| | |||| .|          .. |..|        |..| .           .. |.|...|...||..| .||||.|..     |..||.
LGCLMYEMLTGYPPFYGDNPQENRHPFRNPMEMFQKIMNGRYFINWKVKFPFPEDPQFPEDRWFSPEAKDLIKKLLCKDPEKRLGCGGNDFGDKGAEEIK

NHPFF
|||.|
NHPWF
Kinase 11909.AA RSK 37-302 44 1.1e-167 563.39 In-house 1-271 (271) Show / Hide 
Range on Protein: 37-302
Range on HMM: 1-271/271
Sequence Identity: 44% (124 aa)

FEFIKCIGTGSFGKVYLVKKK---QTEDLYAMKILRKDQIKNKTQLIQTKAERYILENVDSPFVVQLAYAFQSQTKLYIVMEFCQGGDIFGHMVKQPFFP
.|...|||.|||.|||..||.   .|...|||||..|.....|.. .....||.||.....||.|.|.|.||...|.|..|.|..|||.|....||..|.
YELHECIGQGSFSKVYVCKKCQHKDTNQHYAMKIIKKATRDVKDR-VCWEEERIILRYGHHPFIVKLHYVFQDEGKVYMIMDFMRGGDLFDRLLKQKMFS

ENKIKFYAAEIFLALEKLHEQGIVYRDLKPENILVSAT----GHIKLTDFGLSKKLKSRDEITYSFCGTAEYMAPEIISKQGHDVASDWWSFFKYLNISK
|...|||.|||.||.|.||.||||.|||||||||....    ||||..|||..|.|.........||.||.|||||....||||.|.|||||        
EREVKFYMAEIALAMEYLHSQGIVHRDLKPENILYDDESGNPGHIKICDFGFAKQLRDENGMLMTFCYTANYMAPEVLKRQGHDQACDWWSF--------

GAVLYEMLHGAPPFYEKNKERMMDKLVNQDVVI-------KDKYSKECQSLLRGLLTRDKTKRLGNGPEGTQEIRNHPFF
|...||||.|..||..|.....|..........       .|..|.|...|||..|.||...|||.||.|...|..||.|
GVLMYEMLTGCTPFQNKPRDTPMNIIQRIKLGMFSMTHGNWDFISDEAKDLLRMMLHRDPHNRLGAGPNGVEQIKQHPWF
Kinase 11909.AA SGK 37-302 46 1.1e-140 437.49 In-house 1-283 (283) Show / Hide 
Range on Protein: 37-302
Range on HMM: 1-283/283
Sequence Identity: 46% (135 aa)

FEFIKCIGTGSFGKVYLVKKKQT------------------EDLYAMKILRKDQIK-------NKTQLIQTKAER-YILENVDSPFVVQLAYAFQSQTKL
|.|.| || |||||||.||.|..                  ...||||.|.|..|        .| .   ..|||  || |. .|| |.| |||| ..||
FDFLKVIGKGSFGKVYQVKHKDDETCQRVWLIFQSLLSQSEDKFYAMKVLQKQHIINEYRQDLKKKEQKHIMAERNVILKNMKHPFIVNLHYAFQTKWKL

YIVMEFCQGGDIFGHMVKQPFFPENKIKFYAAEIFLALEKLHEQGIVYRDLKPENILVSATGHIKLTDFGLSK-KLKSRDEITYSFCGTAEYMAPEIISK
| ||.. .||. | |. .   ||| . .|||||| .||| ||.| |.||||||||||  . ||..||||||.| . |  |. | .|||| ||.|||.. |
YFVMDYVNGGEMFYHLQREKHFPEDRARFYAAEIVCALEYLHSQDIIYRDLKPENILLDHQGHCCLTDFGLCKEGIKTNDT-TFTFCGTPEYLAPEVLRK

QGHDVASDWWSFFKYLNISKGAVLYEMLHGAPPFYEKNKERMMDKLVNQDVVIKDKYSKECQSLLRGLLTRDKTKRLGNGPEGTQEIRNHPFF
|.|| . |||.         |.|||||..|.|||| .||. | |.  ||.  |.   | .. .|. |||..|..||||   ..  ||.|||||
QPHDRTVDWWCL--------GCVLYEMMYGLPPFYSRNKQQMYDNIINQPLQIPPQMSNDAWDLIQGLLQKDPKKRLGTK-RDFMEIKNHPFF
Kinase 11909.AA AktR 37-302 45 1.9e-127 429.73 In-house 1-268 (268) Show / Hide 
Range on Protein: 37-302
Range on HMM: 1-268/268
Sequence Identity: 45% (126 aa)

FEFIKCIGTGSFGKVYLVKKK-QTEDLYAMKILRKDQIKNKTQLIQTKAERYILE-NVDSPFVVQLAYAFQSQTKLYIVMEFCQGGDIFGHMVKQPFFPE
|...||.| | |||||||.|| .. ..||||...|  |....|  .|  ||.|.|  .. || |.| |.||...||...||.|.||..| |  |. .| |
FHVYKCLGKGAFGKVYLVQKKRDNQKQYAMKMIKKKKIIERNQMHHTITERNIMEMCCNHPFIVKLHYCFQTKEKLFFIMEYCPGGELFQHLKKKKKFSE

NKIKFYAAEIFLALEKLHEQ-GIVYRDLKPENILVSATGHIKLTDFGLSK--KLKSRDEITYSFCGTAEYMAPEIISK-QGHDVASDWWSFFKYLNISKG
....||.|.| |||| ||..  |.||||||||||    ||.|.|||||||  . ...||..|||||| ||||||.| | .||. ..|||.|        |
EQARFYFAQILLALEYLHQHMNIIYRDLKPENILLDEDGHVKITDFGLSKLQFMMHYDEKAYSFCGTPEYMAPEMITKKKGHNKSVDWWAF--------G

AVLYEMLHGAPPFYEKNKERMMDKLVNQD-VVIKDK--YSKECQSLLR-GLLTRDKTKRLGNGPEGTQEIRNHPFF
...|||. | |||| ||...| .|  ... . ...    |..|..|.  .|| .. .|||| . .|..||..||.|
IFIYEMVTGCPPFYHKNQNQMFQKIKIKQQNKFPYPSYFSSQCKDLIQRKLLCKNPNKRLGYYCNGWEEIKSHPWF
Kinase 11909.AA RSK 40-302 43 2.7e-118 399.32 In-house 1-278 (278) Show / Hide 
Range on Protein: 40-302
Range on HMM: 1-278/278
Sequence Identity: 43% (123 aa)

IKCIGTGSFGKVYLVKKK---QTEDLYAMKILRKDQIKNKTQ-LIQTKAERYILENVD-SPFVVQLAYAFQSQTKLYIVMEFCQGGDIFGHMVKQPF---
.|  |.|..|||.|..|.   .|. .||||.|.|  |...   .  |..|| ||| .  .||.|.| |||| ..|||..||.| ||. | |  |. .   
LKVLGQGGYGKVFLCRKCTHHDTGQIYAMKVLKKAKIVQRQKDTRHTMTERNILERCQQHPFIVTLHYAFQTEGKLYLIMEYCRGGELFTHLQKEKHFGC

FPENKIKFYAAEIFLALEKLHEQGIVYRDLKPENILVSA---TGHIKLTDFGLSKKLKSR-DEITYSFCGTAEYMAPEIIS---KQG-HDVASDWWSFFK
| |.  .||.||| ||.| ||.|||..|||||||||       |||||||||..|... .  . |..||.|.||||||..    .|| || | ||||.  
FSEDEACFYMAEIVLAVEHLHQQGIIHRDLKPENILYDDESNEGHIKLTDFGFCKQFRCDHNQWTMTFCYTIEYMAPEMLKRANQQGGHDKACDWWSL--

YLNISKGAVLYEMLHGAPPFYE---KNKERMMDKLVNQD--VVIK--DKYSKECQSLLRGLLTRDKTKRLGNGPEGTQEIRNHPFF
      |...|||| |.|||.    .|..  |..  . .  . ..  .. |.|...|.|..|.||  |||| ||....||..||.|
------GVLMYEMLTGCPPFQGPNDNNRKEIMKRIQKGKFSLTMPNWQYLSQEAKDLIRKMLHRDPHKRLGCGPQDAEEIKQHPWF
Kinase 11909.AA p70 37-302 38 5.5e-106 358.41 In-house 1-299 (299) Show / Hide 
Range on Protein: 37-302
Range on HMM: 1-299/299
Sequence Identity: 38% (118 aa)

FEFIKCIGTGSFGKVYLVKKKQ---TEDLYAMKILRKDQI-KNKTQLIQTK-------------------------AERYILENVDSPFVVQLAYAFQSQ
|| .| .| | .|||..|.| .   |  .|||| ||| .|  | . .  |.                         ||| ||| | .||.. |.||||  
FELLKVLGKGGYGKVFQVRKVTGEDTGKIYAMKVLRKAKIVRNQKDTAHTREDEDKNDGNNNDNDDGLSKRLERTFAERNILEEVKHPFICDLHYAFQTN

TKLYIVMEFCQGGDIFGHMVKQPFFPENKIKFYAAEIFLALEKLHEQGIVYRDLKPENILVSATGHIKLTDFGLSKKLKSRDEI----------TYSFCG
 ||| . |.  ||  | |  ..  ..|.  .||..|| .||| ||..||.||||||||.. .. ||..||||||.|.    ...          |..|||
GKLYLILEYLHGGELFMHLERHGIWMEDTACFYLSEIICALEHLHQHGIIYRDLKPENCMLNQQGHVVLTDFGLCKESIHDGAVDEEDPENVNATHTFCG

TAEYMAPEIISKQGHDVASDWWSFFKYLNISKGAVLYEMLHGAPPFYEKNKERMMDKLVNQD--VVIKDKYSKECQSLLRGLLTRDKTKRLGNGPEGTQE
| |||||||... ||. | ||||         |. .| || |.|||   |.   .||       . .  . ..|   |.. || |. |.|.| |||  ..
TIEYMAPEILMRCGHNHAVDWWSL--------GCLMYDMLTGGPPFTGENRKKTIDKILKGKQGLKLPPYLTHEMRDLIKKLLKRHPTQRWGAGPEDAAD

IRNHPFF
|. ||||
IQEHPFF
Kinase 11909.AA RSK-Unclassified 37-302 40 1.9e-102 322.69 In-house 1-283 (283) Show / Hide 
Range on Protein: 37-302
Range on HMM: 1-283/283
Sequence Identity: 40% (118 aa)

FEFIKCIGTGSFGKVYLVKKKQTEDLYAMKILRKDQI--KNKTQLIQTKAERYILENVDSPFVVQLAYAFQSQTKLYIVMEFCQGGDIFGHMV--KQPFF
|. .. || |.|||||||.||.|. .||||.| |...  .||.. . |  |. |.   . ||.|.| ..||.| .|| .||.| |||.| |.   |.  |
FIKHRLIGQGDFGKVYLVRKKDTQQIYAMKVLHKHKMIRHNKIKYVMT--EQNIMATTNHPFIVTLYHSFQTQDYLYLCMEYCMGGDFFRHLQTRKEKCF

PENKIKFYAAEIFLALEKLHEQGIVYRDLKPENILVSATGHIKLTDFGLSKKL--------K-------------SRDEITYSFCGTAEYMAPEIISKQG
 |....|||.|. .||| || ....||||||.||.    ||..||||.||..         |             .    | ||||| ||.|||.|   |
CEDDVRFYASEVTAALEYLHKRDFIYRDLKPDNIVLHQEGHVMLTDFDLSIQAKDSKKPVMKGSAQSTYVDTKICDHGFRTNSFCGTEEYLAPEMIRRCG

HDVASDWWSFFKYLNISKGAVLYEMLHGAPPFYEKNKERMMDKLVNQDVVIK--DKYSKECQSLLRGLLTRDKTKRLGNGPEG-TQEIRNHPFF
|  | |||          | |.|||| | ||.|  ||. .      ..| .      |..|..|.. ||.|   |||| .  |  ..|. ||||
HTKAVDWWTL--------GIVMYEMLFGCPPYYGNNKNETFYNIEKNHVKFPHDSYISNNCRDLIKKLLQRNPAKRLGCK-MGDADDIKRHPFF
Kinase 11909.AA PKA 37-302 42 1.3e-101 343.88 In-house 1-263 (263) Show / Hide 
Range on Protein: 37-302
Range on HMM: 1-263/263
Sequence Identity: 42% (116 aa)

FEFIKCIGTGSFGKVYLVKKKQTEDLYAMKILRKDQIKNKTQLIQTKAERYILENVDSPFVV-QLAYAFQSQTKLYIVMEFCQGGDIFGHMVKQPFFPEN
||.|. .||||||.|.|...|.... ||||.|.|..|.   |   .. |. || |...||.| .. . ||  ..|| |||...||..| .. |   |.. 
FEIIQTLGTGSFGRVMLCRHKHSGNYYAMKMLKKQEIVRLKQVEHVHNEKNILQNIKHPFIVKKMYWTFQDDRYLYMVMEYVPGGEMFSYLRKSGRFSNP

KIKFYAA-EIFLALEKLHEQGIVYRDLKPENILVSATGHIKLTDFGLSKKLKSRDEITYSFCGTAEYMAPEIISKQ-GHDVASDWWSFFKYLNISKGAVL
  ||||| .|.|||| || | |.||||||||||    ||||.|||| .||...|   |.. ||| ||.|||||.   ||  . |||..        | . 
HAKFYAASQIVLALEYLHSQNIIYRDLKPENILIDKNGHIKITDFGFAKKVDDR---TWTLCGTPEYLAPEIIQSKNGHGKSVDWWAL--------GILI

YEMLHGAPPFYEK--NKERMMDKLVNQDVVIKDKYSKEC---QSLLRGLLTRDKTKRLGNGPEGTQEIRNHPFF
|||| | ||||..  ..  . .| .| ..     ...      .|.. ||..| |||.||  .|.. |.||..|
YEMLAGYPPFYDHNRDPMQIYEKICNGKIKFPRHFDSDANYFKDLIKKLLQVDLTKRYGNMKNGVNDIKNHKWF
Kinase 11909.AA S_TKc 37-302 35 5.4e-101 342.73 SMART 1-231 (231) Show / Hide 
Range on Protein: 37-302
Range on HMM: 1-231/231
Sequence Identity: 35% (99 aa)

FEFIKCIGTGSFGKVYLVKKKQTEDLYAMKILRKDQIKNKTQLIQTKAERYILENVDSPFVVQLAYAFQSQTKLYIVMEFCQG--GDIFGHMVKQPF---
.|... || |.|||||....| |  ..|.||..          .... |. ||.. . |..|.| ..||. ..||.|||.| |  || | ...|..    
YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK----------EHIRREIQILKK-HHPNIVKLYDVFQD-DHLYMVMEYCDGDLGDLFDYIKKRGRHGL

---FPENKIKFYAAEIFLALEKLHEQGIVYRDLKPENILVSATGHIKLTDFGLSKKLKSRDEITYSFCGTAEYMAPEIISKQGHDV-ASDWWSFFKYLNI
   |||  ..||...|..||| .|..||..|||||||||..   |||..||||...|       ..|||| .|||||..   |..  ..||||.      
RFPFPE-HARFYMYQICCALEYCHSHGIIHRDLKPENILLDE--HIKICDFGLARQL-------TTFCGTPWYMAPEVL---GYGKCKCDWWSC------

SKGAVLYEMLHGAPPFYEKNKERMMDKLVNQDVVIKDKYSKECQSLLRGLLTRDKTKRLGNGPEGT--QEIRNHPFF
  | .||||| | |||.  . ..|..|..          |.|. ...|..|..| .||..     .  ..|..||.|
--GCILYEMLCGYPPFP--QMQMMFKKIG----------SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF
Kinase 11909.AA Ciliate-E2-Unclassified 37-302 28 3.4e-91 309.26 In-house 1-352 (352) Show / Hide 
Range on Protein: 37-302
Range on HMM: 1-352/352
Sequence Identity: 28% (103 aa)

FEFIKCIGTGSFGKVYLVKKKQTEDLYAMKILRKDQIKNKTQLIQ---------TKAERY-------------ILENVDSPFVVQLAYAFQSQTKLYIVM
...||.||.|.|||||....|..  .||||.. | ||... |  .         .  ..              || | ..||.| . |.||.. ..||||
YKIIKQIGQGGFGKVYKCQHKKQKQYYAMKYMKKIQIYKQKQIMNKDEIMNEMKEMNNKKKYHQRKYNKIMQQILLNHPHPFIVKMFYCFQDKQNIYIVM

EFCQGGDIFGHMVKQPF-----------------FPENKIK-----FYAAEIFLALEKLHEQG-IVYRDLKPENILVSATG---HIKLTDFGLSKKLKSR
|.|.||| . .. |...                 |.|...|     ||.|.| ..||.||... |..||.||||||..  |   .||..|||.|||... 
EYCEGGDLWQYIKKRKKQKQKGNDLFHNMKQRKIFTEQQAKYKKAKFYFAQILQGLEYLHHKNNIIHRDIKPENILFDNNGKNYYIKIIDFGISKKYQQN

---------------DEITYSFCGTAEYM----APEIISKQGHD----VASDWWSFFKYLNISKGAVLYEMLHGAPPFYEKNKER---------------
               ......|||| .||    |||.. .|..|     ..|.||.        | .||||| | .||| .|.|                
NNCDTNQQQKMQIWKQQMMWTFCGTPNYMPQYTAPEVLQGQNYDHSKAYKCDIWSL--------GVILYEMLFGYYPFYDNNCEQHQQLITQWINNAYRK

-MMDKLVNQDVVIK--------DKYSKECQSLLRGLLTRDKTKRLGNGPEGTQEIRNHPFF
 . ..  .... ..        .. |.|.. ... || ..  |.... . . ..| |||.|
QLYQNIKQKNIQFPKFPWQQIPKHWSPEAKDFINDLLQKMLKKNPNKRI-TFEQILNHPWF
Kinase 11909.AA Pkinase 37-302 30 1.2e-87 302.3 Pfam 1-293 (293) Show / Hide 
Range on Protein: 37-302
Range on HMM: 1-293/293
Sequence Identity: 30% (94 aa)

FEFIKCIGTGSFGKVYLVKKKQTEDLYAMKILRKDQIKNKTQLIQTK-AERYILENVDSPFVVQLAYAFQSQTKLYIVMEFCQGG----DIFGHMV--KQ
......|| ||||.||. ..| |....|.||..|. .| . . . .. .| .|. ....|..|.| ..|.. ...|.|||.|.||    | | ..   ..
YHIGRKIGSGSFGCVYKCHHKGTGKIVAVKIIKKRHEKSWKDQTHRRLSEIQIMKRLNHPNIVRLYDWFEDKDHIYMVMEYCEGGLYVMDLFDYISTWRH

PFF--PENKIKFYAAEIFLALEKLHEQGIVYRDLKPENILVSATGHI----KLTDFGLSKKL-KSRDEITYSFCGTAEYMAPEIIS-KQGHDVASDWWSF
  |  .|. .|||. .|. .|| .|..||..|||||||||.. .|||    |..||||.|..   ... ...|||| .|||||.|   |... ..|.||.
GCFYFSEWECKFYMYQILRGLEYCHSMGIIHRDLKPENILIDNNGHIDACVKICDFGLAKQFDY-NNS-MTTFCGTPWYMAPEVIRGGQYYGPKVDMWSC

FKYLNISKGAVLYEMLHGAPPFYEK------NKERMMDKLVNQDVVIKDKYS---------------------KECQSLLRGLLTRDKTKRLGNGPEGTQ
        | .||||| | |||...      ..  |...    ..     ..                     .||.......|..| .||..      .
--------GCILYEMLCGRPPFPGHCWHDNHDQMQMICRIMGPPLHFDWPWWCSISYFFFRHWHFHWTFHNWSEECKDFIKWCLCKDPKKRPT-----AE

EIRNHPFF
.| .||.|
QILQHPWF
Kinase 11909.AA TyrKc 37-286 19 7e-13 -14.4 SMART 1-280 (280) Show / Hide 
Range on Protein: 37-286
Range on HMM: 1-280/280
Sequence Identity: 19% (59 aa)

FEFIKCIGTGSFGKVYLVKKKQTEDLYAMKILRKDQIKNKTQLIQTKAERYILENV--DSPFVVQLAYAFQSQ-------TKLYIVMEFCQGGDIFGHM-
 ...| .| | ||.||. . |      | | |..|       .     |  |. ..  . | .|.|  .  .|         |.||||.. .||   .  
ITLGKKLGEGAFGEVYKGTWK---IQVAVKMLKEDA------REDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPHGDLKDYLR

VKQPFFPENKIKFYAAEIFLALEKLHEQGIVYRDLKPENILVSATGHIKLTDFGLSKKLKSR-------DEITYSF--CGT----AEYMAPEIISKQGHD
 ..| ..  .   ..  |    | ||..... |||   |.||.. ...| .|||||.....        | .. .   .|        |||| | .    
KHRPKLCMKDLLSFCWQIACGMEYLHSKNCIHRDLAARNCLVGENHTVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGKTMLPIRWMAPECINYGKFT

VASDWWSFFKYLNISKGAVLYEML-HGAPPFYE-----KNKERMMDKLVNQDVVIKDKY---------SKECQSLLRGLLTR---------DKTKRL
 .|| |||        | ...|..  |..| ..     .. .... .. . .   . ..         ..|  .. .    .         .  ...
TKSDVWSF--------GVCMWEIFTYGQQPYPGMIQQMMSNQEVIEYVKQGYRMPQPPNDYPMSFVCCPDEMYQIMKQCWHEDPEDRPTFSEIHECF
Kinase 11909.AA S_TK_X 303-368 24 2.2e-11 45.06 SMART 1-79 (79) Show / Hide 
Range on Protein: 303-368
Range on HMM: 1-79/79
Sequence Identity: 24% (20 aa)

NNVDWDKFLR--LEVQPPYIPKVS----DKYDLRNIDNNFLKMDSKDTPGDMVGS-ALKFSKKNE---------FNGFTYER
 ..|||| ..   |..||..||..    .  |..| |  | ... .    ... . ... .  ||         | |||| .
RGIDWDKLYNQQKEIEPPFKPKIKEVYASPTDTSNFDPEFTEETPM---LTPDDPPLSNSMWQNEMETEIPPDPFRGFTYVF
Kinase 11909.AA Pkinase_C 322-366 28 1.3e-05 23.11 Pfam 1-42 (46) Show / Hide 
Range on Protein: 322-366
Range on HMM: 1-42/46
Sequence Identity: 28% (13 aa)

KVSDKYDLRNIDNNFLKMDSKDTPGDMVGSALKFSKKNEFNGFTY
.|... | .| |  | ... .|||  . .. .  .. ..| ||||
QVKSPTDTSNFDPEFTDEPPMDTP--PDWR-MSSGDQEPFRGFTY
Kinase 11909.AA Pkinase_Tyr 37-121 28 5.8e-05 17.43 Pfam 1-93 (270) Show / Hide 
Range on Protein: 37-121
Range on HMM: 1-93/270
Sequence Identity: 28% (27 aa)

FEFIKCIGTGSFGKVYLVKKK----QTEDLYAMKILRKDQIKNKTQ--LIQTKAERYILENV-DSPFVVQLAYAFQ-SQTK--LYIVMEFCQGGD
 .|.| .| |.||.||. . |    .|.   | |.| |.    . |  .    .|  |. .  . | .|.|  .    .    .|||||....||
ITFGKKLGEGAFGEVYKGTWKGDPDNTKIPVAVKML-KE-GAMHEQNCREDFMREAKIMKQLGHHPNIVRLYGVCTDQGEPNQIYIVMEYMPHGD
Kinase 11909.AA Pkinase_Tyr 165-190 34 0.000548 14.13 Pfam 141-166 (270) Show / Hide 
Range on Protein: 165-190
Range on HMM: 141-166/270
Sequence Identity: 34% (9 aa)

NILVSATGHIKLTDFGLSKKLKSRDE
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NCLVTENNVVKICDFGLARDIYNDDY