Gene 10338 (Tetrahymena)

10338

Species: Tetrahymena
Alias: PreTt10338, 10338, 40.m00223, TTHERM_00378840, 80
External Links: Tetrahymena Genome Database (TGD)
Annotation:

Classification

Group: Atypical
Family: Alpha
Subfamily: Alpha-Unclassified

Sequence

Name Sequence Type Origin Length Description Download
10338.AA Protein None 274 None Fasta, JSON
10338.kin_dom Protein Kinase Domain None 102 None Fasta, JSON
10338.NA RNA None 825 None Fasta, JSON

Protein domain

Protein domains of 10338.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Kinase 10338.AA Alpha-Unclassified 139-235 38 4.6e-68 221.02 In-house 107-215 (215) Show / Hide 
Range on Protein: 139-235
Range on HMM: 107-215/215
Sequence Identity: 38% (42 aa)

LISLESYLEGEYRKFNSNSG-------WSDESYPLMQAFSHFTFYNSGGQEILCDLQG-IDEIDSKTIQLTDPAILSIRSRFG--DSDIGYKKLQYWIKN
.||.|.||.||..|...|.|       |..|.|.......|.|........|.||||| .||.|.||...|||.|..||.|..  ....|.....||..|
CISVEPYLIGEFVKYSNNTGKEINFVKWEYEAYQYCCTYQHWTYQWTNHCDIVCDLQGWVDENDKKTWKMTDPQIHTIRQRYQGFKTNCGMRFIDYWFNN

H--KCNHIC
|  .|||.|
HHVQCNHYC
Kinase 10338.AA Alpha 129-235 38 2.2e-65 184.97 In-house 99-215 (215) Show / Hide 
Range on Protein: 129-235
Range on HMM: 99-215/215
Sequence Identity: 38% (45 aa)

LLGKHYKEG-DLISLESYLEGEYRKFNSNSGWSD------ESYPLMQAFSHFTFYNSGGQEILCDLQ-GIDEIDSKTIQLTDPAILSIRSRFGDSDIGYK
.|  ... .  ..|.|.|.||||.|.|.|.||.|      |...|||||||.|...|.||....||| |..|......|...||.|.....|||...||.
ELIHCHNHNIKYYSVENYMEGEYQKYNNNAGWVDFLTDDNEFNQLMQAFSHWTWQYSNGQLMVVDLQWGVGEWKLTDPQIHCPAKLDQGMKFGDGNCGYE

KLQYWIKNH--KCNHIC
........|  .|||.|
GMFRFFYTHHVQCNHYC
Alpha_kinase 10338.AA Alpha_kinase 22-235 22 3.5e-65 226.84 Pfam 1-225 (225) Show / Hide 
Range on Protein: 22-235
Range on HMM: 1-225/225
Sequence Identity: 22% (56 aa)

FAEGSSRKAYRCEVV--KGPNLGKKGVVKRYKNHIENKKL--------DNFKNEQLIWQQATVYARLFNKEINIIMENVKAKNCTPEFELFINQHYRRIV
||.|  |...|....  ........ |.|.||... | .         | ....  ..  .  ... ||....  ..|.. ....              .
FAQGAMRWCFRMFDTWDPNWRNNQNCVAKWYKKIK-NYNQKQSIYVEEDYYFQDCKMQMICQQWMEKFNQKLQ--EHNNPPPPIE--------------F

MPQPQIIQIEKKSLLASLL-----GKHYKEGDLISLESYLEG-EYRKFNSNSGWS-------DESYPLMQAFSHFTFYNSGGQEILCDLQGID--EIDSK
.. . ....|... .....     .. ...|.....|.|.|| |..|.|.|.||.       |. . .||||||||.  |.|| ..||.|| .  ..   
YDCCIVYELEDHNKPDCYQGFFSYRT-DWGGKYWYMEPYIEGCEFVKYNNNYGWVYDNMDRNDPWNQYMQAFSHFTYHRSNGQMMVCDIQGVGYNNK---

TIQLTDPAILSIRSRF------GDSDIGYKKLQYWIK-NHKCNHIC
.. ||||.|..  ...      |. . |..  ..... .|||||||
CYYLTDPQIHTKDGNYEMDFDEGMGNLGQEGIEKFFQNQHKCNHIC
Alpha_kinase 10338.AA Alpha_kinase 1-235 18 6.7e-32 113.22 SMART 1-255 (255) Show / Hide 
Range on Protein: 1-235
Range on HMM: 1-255/255
Sequence Identity: 18% (51 aa)

MGQNICVSTKTGDVYKF-HHSCFAEGSSRKAYRCEVVKGP----NLGKKGVVKRYKNHIENKK--LDNFK-------NEQLIWQQATVYARLFNKEINII
... .| .|     .|  .. .||.|  |..|. . . .     . |.. |.|..|  ... .   ..|.        .      .  .|. ||.     
DNKWTCQET----CVKIKEPKPFAKGAMRWCYWGCDWSEHMHCFCHGWECVAKYFKKEYKRTWDEERYFHETLHLCLRDVEMQMMCKHWANEFNQ-----

MENVKAKNCTPEFELFINQHYRRIVMPQPQIIQIEKKSLL--ASLLGKHYKEGDL---------------ISLESYLEGEYRKFNSNSGWSDES-YPL--
                ..| .  .  .....|...   ..  ...  .... .                 ...| ..|||..|.|.|.|| ... ...  
----------------EAQ-HNPCP-KKIDFIPCYVFHFPRRIPAEYDRNIPYWFSYRTTDQMMVMCCCIFHMEPFMEGEFVKYNNNNGWVNDCMRWTTT

----------MQAFSHFTFYNSGGQEILCDLQGI-DEIDSKTIQLTDPAILSI---RSRFGDSDIGYKKLQYWIKNHKCNHIC
          .|||||.|.  |..| ..||.||   . ..  . .|||.|...   .  ||.   | . . ... .|.||.||
SQRRTEMFEYCQAFSHWTYEWSNHQMLVCDIQGVIHKNGD-LYYYTDPQIHTEDQNGYGFGMGNLGQEGIEKFFQTHQCNQIC
Kinase 10338.AA VWL 141-240 37 6.7e-20 56.08 In-house 106-206 (206) Show / Hide 
Range on Protein: 141-240
Range on HMM: 106-206/206
Sequence Identity: 37% (40 aa)

SLESYLEGEYRKFNSNSGW----SDESYPLMQAFSHFTFYNSGGQEILCDLQGIDEIDSKTIQLTDPAILSIRS--RFGDSDIGYKKLQYWIKNHKCNHI
. | |.||.| |.| |.||     .|  .| |||||||.  | |.    |||| ..      .|||| |       .||. . ||  .      |.|| .
FVENYIEGDYQKYNNNAGWCNQTDMEYNQLSQAFSHFTWQYSQGYCMIVDLQGNED-----GMLTDPQIHCLDQSHKFGQGNLGYEGMLRFFMTHQCNKY

CHALKL
|  | |
CQKLQL
Kinase 10338.AA ChaK 140-235 32 3.5e-09 32.56 In-house 120-219 (219) Show / Hide 
Range on Protein: 140-235
Range on HMM: 120-219/219
Sequence Identity: 32% (35 aa)

ISLESYLEGEYRKFNSNSGWSDESYP------LMQAFSHFTFYNSGGQEILCDLQGIDEIDSKTIQLTDPAILSI---RSR---FGDSDIGYKKLQYWIK
...| .. ||.||.| | |  ||  |      .| ||||.|.    |  .  ||||. |       ||||...     .|.   ||   .|   .. .. 
FTIEKCMTGEFRKYNNNNG--DEIIPTNTLEEIMLAFSHWTYEYTRGELLVLDLQGVGE------NLTDPSVIKPEEKQSCDMVFGPANLGEDAIRNFRA

NHKCNHIC
 | ||  |
KHHCNSCC