Gene 15771 (Tetrahymena)

15771

Species: Tetrahymena
Alias: 192, 190.m00081, TTHERM_01001520, 3820.m00302, 15771, PreTt15771
External Links: Tetrahymena Genome Database (TGD)
Annotation:

Classification

Group: Atypical
Family: Alpha
Subfamily: VWL

Sequence

Name Sequence Type Origin Length Description Download
15771.AA Protein None 1543 None Fasta, JSON
15771.kin_dom Protein Kinase Domain None 206 None Fasta, JSON
15771.NA RNA None 4632 None Fasta, JSON

Protein domain

Protein domains of 15771.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
HEAT 15771.AA HEAT 168-198 19 0.007832 13.67 Pfam 1-31 (31) Show / Hide 
Range on Protein: 168-198
Range on HMM: 1-31/31
Sequence Identity: 19% (6 aa)

LTRPLIDQMQDNDSKIRFACLEGLYHITFAL
.  .|.  ..|.|...| |... | ..   .
ILPHLLKCLNDPDWEVREAACWCLGQLCEHC
HEAT 15771.AA HEAT 209-228 40 20.14287 1.86 Pfam 1-20 (31) Show / Hide 
Range on Protein: 209-228
Range on HMM: 1-20/31
Sequence Identity: 40% (8 aa)

IFETLVTKVTDMDNSVRSAA
|...|..  .| | .||.||
ILPHLLKCLNDPDWEVREAA
HEAT 15771.AA HEAT 295-325 29 0.033155 11.5 Pfam 1-31 (31) Show / Hide 
Range on Protein: 295-325
Range on HMM: 1-31/31
Sequence Identity: 29% (9 aa)

FLEQLFLNMSDSNREIRQSAELCLRGFLEEI
.|. |.  ..|.. |.|..|  ||  ..| .
ILPHLLKCLNDPDWEVREAACWCLGQLCEHC
HEAT 15771.AA HEAT 468-498 19 10.091658 2.9 Pfam 1-31 (31) Show / Hide 
Range on Protein: 468-498
Range on HMM: 1-31/31
Sequence Identity: 19% (6 aa)

AMPMLQQMLDEKRESTAQSALVWMRQLIKYY
 .|.| ..|. . ..  ..|.  . ||....
ILPHLLKCLNDPDWEVREAACWCLGQLCEHC
DUF3434 15771.AA DUF3434 554-861 24 8.7e-81 279.49 Pfam 1-227 (243) Show / Hide 
Range on Protein: 554-861
Range on HMM: 1-227/243
Sequence Identity: 24% (85 aa)

QNQKIL-NKSDIIIKQLCNILNP----ELVFKTMASELRKYDDINFVSPFVRSLDLILLTDSV--------------------QIFSCLKNILSYNPVSA
...|.| .....||.|||. |||    | ...|... | |..|..|.| .|..| .|||| .                     ..|||| .  ..|||||
TDRKLLETRGNFIIRQLCVCLNPDEQCERIYRTLCEILEKEEDLEFASMMVQTLNWILLTSPELFDLRNKLRRNLDNKDSQDWMLFSCLYRCWCHNPVSA

ITLCFLTQAYELAYNIIMSFCEIELNKSNLTQICELIYLLEKPIFVQ-------HEKYPYLLKSLHGLMMLLP-QGETYNLLASRIKLVGQGSTDQQTMV
|.||.|.|.||.||||..||.|.|.| . |.||. |..||| |.| .       .||||||.|.|.||.|.|| |....|.| .|...|           
ISLCLLCQNYEHAYNICQSFAELEMNVNFLVQIDKLVQLLESPVFTYLRLQLLEPEKYPYLYKCLYGLLMILPQQSSAFNTLRNRLQCVP----------

SQPWDKLNKIQQNFYQPPYLFKIITTMDQKKKTNKLHCHFFHLTGNCKKADKCPFLHGKKLNGCPNGDKCPIQILHISLEENKFITPNKQKSLQRDQNSL
                                                                      ...|||. .... .....            
----------------------------------------------------------------------NLWILHR-SNPR-PYSFD------------

NNSSSDTKSLSPEQSSSDKKQCKQITVPKELEDEEVKHNFQ
                    ||.. |.||. . |. ....|
--------------------QCNTDTNPKHDQEEQSRIDWQ
ZnF_C3H1 15771.AA ZnF_C3H1 753-779 29 1.1e-05 26.09 SMART 1-31 (31) Show / Hide 
Range on Protein: 753-779
Range on HMM: 1-31/31
Sequence Identity: 29% (9 aa)

TNK-LHCHFFHLTG---NCKKADKCPFLHGK
..|   | .|...|   .|.. |.|.|.|..
RYKTPPCKYFMRRGPPWYCPYGDRCKFAHPP
Zf-CCCH 15771.AA zf-CCCH 758-779 40 2.5e-05 21.73 Pfam 6-27 (27) Show / Hide 
Range on Protein: 758-779
Range on HMM: 6-27/27
Sequence Identity: 40% (9 aa)

CHFFHLTGNCKKADKCPFLHGK
|..|. || |.  |.|.| |..
CRYFMRTGYCPYGDRCKFAHPQ
VWA 15771.AA VWA 921-1107 12 2e-06 28.77 SMART 1-193 (193) Show / Hide 
Range on Protein: 921-1107
Range on HMM: 1-193/193
Sequence Identity: 12% (27 aa)

ELDLMFIMDCTGSM-SGWIQAVKDEILSIIAAIKDINKGNTSIRISFIGYRDYGSIQRFSIFDFSSEIDSFQNFLNQIQA----EGGNDSEEDVAGGFKH
.||..|..|..|||  ...|.||. | ... ..        ..|.. ... |  . .. . .. ..  |.... ....|     .       . . . ..
WLDIVFVIDGSGSMGPNNFQQVKQFI-KFVEQLD-------GDRVGIVQFSD--DVRVEFPLN-YQDKDDVLKAIDNLQYKGKHDYFMGGGTNTG-ALQY

ANLQ------QWKSQA----------KYAVFIADCPAHGREYSDGHDDRYPDGDPDGVDLKQEFKNLIKKGVQLYTIQITD-QTKKMFELFKQFNN----
|  .        . .|          |  ....|  ..                 |  |... ...| ..||....| . .  . .. ..  .  .    
AMQNLFHERQG-RRGAGRPTKFWNVPKVIIVFTDGYSNDG-------------PHDPEDIRKAARELRRSGVKIFVIGVGNDDM-ELRQIASCP-GEHHF

--------EVCGQDLQILDLG
         ..  ...| .| 
FDVYDYDDLPDIFQHIIDWLC
VWA 15771.AA VWA 923-988 25 0.000131 15.86 Pfam 1-65 (190) Show / Hide 
Range on Protein: 923-988
Range on HMM: 1-65/190
Sequence Identity: 25% (18 aa)

DLMFIMDCTGSMSG---WIQAVKDEILSIIA-AIKDINKGNTSIRISFIGYRDYGSIQRFSIFDFSSEID
|..|..|. |||..   . . ||| | ...  .      |. ..|.. . | |.   . |.. |..|. |
DIVFVIDGSGSMGEQNRFEK-VKDFIKNFVEKNLD---IGPDGTRVGLVQYSDDVR-TEFPLNDYQSKDD
Kinase 15771.AA VWL 1234-1436 67 2.2e-187 563.41 In-house 1-206 (206) Show / Hide 
Range on Protein: 1234-1436
Range on HMM: 1-206/206
Sequence Identity: 67% (140 aa)

IKTKLQISRIPFAEGAMRYAFYAKDTLLNQKLVVKLNKKQHKSDPTLNKADMIKDLESQFICQHIVNQFNDRVSEHVNTTENLKNFVHCYIYEFTDP-SH
||||..||.|||||||||||..||||.||||.|.|..|||||..|..||.|||||.||||.||||||.|||||||||.||.|..|||||||||.|.. .|
IKTKVRISNIPFAEGAMRYAYHAKDTYLNQKMVAKQYKKQHKQNPKINKEDMIKDIESQFVCQHIVNCFNDRVSEHVQTTANILNFVHCYIYEVTHHYNH

PFKFYQAENYIPGEYVKFNNNSGWCDLKFDEPGLLSQALSHFSYQVTEGYLMIVDLQGVG-GMLTDPQIHCLDQ-NRFGLGNLGYSGFFKFFMTHQCNKF
..|.|..||||.|.|.|.|||.|||.....|...||||.|||..|...||.|||||||.. ||||||||||||| ..|| |||||.|...|||||||||.
NIKYYFVENYIEGDYQKYNNNAGWCNQTDMEYNQLSQAFSHFTWQYSQGYCMIVDLQGNEDGMLTDPQIHCLDQSHKFGQGNLGYEGMLRFFMTHQCNKY

CKQLQL
|..|||
CQKLQL
Kinase 15771.AA Alpha 1234-1431 50 2.2e-144 413.8 In-house 1-215 (215) Show / Hide 
Range on Protein: 1234-1431
Range on HMM: 1-215/215
Sequence Identity: 50% (110 aa)

IKTKLQISRIPFAEGAMRYAFYAKDTLLNQKLVVKLNKKQHKSDPTLNKADMIKDLESQFICQHIVNQFNDRVSEHVNTTEN-------LKNFVHCYIYE
..||.|.|..||.|||||||..|.|..|.||.|.|..|||.||. . .....|||.|.|..|.|.|..||.|..|...||..       .|.||||||||
QCTKIQMSSYPFMEGAMRYAMHAWDCWLHQKMVKKQHKKQWKSF-KYVWHHWIKDVERQMVCHHCVREFNQRLWEQEYTTHFNQMKPQPIKQFVHCYIYE

FTDP-SHPFKFYQAENYIPGEYVKFNNNSGWCD-LKFD-EPGLLSQALSHFSYQVTEGYLMIVDLQ-GVG-GMLTDPQIHC---LDQ-NRFGLGNLGYSG
.... .|..|.|..|||. |||.|.|||.||.| |..| |...|.||.||...|...|.||.|||| ||| ..||||||||   ||| ..|| ||.||.|
LIHCHNHNIKYYSVENYMEGEYQKYNNNAGWVDFLTDDNEFNQLMQAFSHWTWQYSNGQLMVVDLQWGVGEWKLTDPQIHCPAKLDQGMKFGDGNCGYEG

FFKFFMTH--QCNKFC
.|.||.||  |||..|
MFRFFYTHHVQCNHYC
Kinase 15771.AA Alpha_kinase 1245-1431 35 6e-81 280.03 Pfam 1-225 (225) Show / Hide 
Range on Protein: 1245-1431
Range on HMM: 1-225/225
Sequence Identity: 35% (81 aa)

FAEGAMRYAFYAKDT-----LLNQKLVVKLNKK----QHKSDPTLNKADMIKDLESQFICQHIVNQFNDRVSEHVNTTENLKNFVHCY-IYEFTDPSH--
||.||||..|...||      .||..|.|..||    . |...  .. ....| ..|.|||.....||.. .||.|   ... |..|. .||. |...  
FAQGAMRWCFRMFDTWDPNWRNNQNCVAKWYKKIKNYNQKQSIYVEEDYYFQDCKMQMICQQWMEKFNQKLQEHNNPPPPIE-FYDCCIVYELEDHNKPD

------------PFKFYQAENYIPG-EYVKFNNNSGWC---DLKFDEPGLLSQALSHFSYQVTEGYLMIVDLQGVG--G---MLTDPQIHCLDQNR---F
              |.. .|.|| | |.||.|||.||.   . . |. . ..||.|||.|. ..|..|..|.||||  .   .|||||||. |.|.   |
CYQGFFSYRTDWGGKYWYMEPYIEGCEFVKYNNNYGWVYDNMDRNDPWNQYMQAFSHFTYHRSNGQMMVCDIQGVGYNNKCYYLTDPQIHTKDGNYEMDF

--GLGNLGYSGFFKFFM-THQCNKFC
  |.||||. |..|||  .|.||..|
DEGMGNLGQEGIEKFFQNQHKCNHIC
Alpha_kinase 15771.AA Alpha_kinase 1231-1431 28 1.8e-49 171.59 SMART 1-255 (255) Show / Hide 
Range on Protein: 1231-1431
Range on HMM: 1-255/255
Sequence Identity: 28% (74 aa)

HSEIKTKLQISRI----PFAEGAMRYAFYAKDT-------LLNQKLVVKLNKKQHKSDPTLNKADMIK--------DLESQFICQHIVNQFNDRVSEHVN
... . .  ...|    |||.|||| .....|.       . ....|.|. ||. | .   .. . ..        | | | .|.|..| || .. .  |
DNKWTCQETCVKIKEPKPFAKGAMRWCYWGCDWSEHMHCFCHGWECVAKYFKKEYKRTW--DEERYFHETLHLCLRDVEMQMMCKHWANEFN-QEAQ-HN

TTENLKNFVHCYIYEFT-------DPSHPFKF---------------YQAENYIPGEYVKFNNNSGWCDLKFD---------EPGLLSQALSHFSYQVTE
....   |. ||. .|.       | ..|  |               .  | .. ||.||.|||.|| .  .          | . . || ||..|. ..
PCPKKIDFIPCYVFHFPRRIPAEYDRNIPYWFSYRTTDQMMVMCCCIFHMEPFMEGEFVKYNNNNGWVNDCMRWTTTSQRRTEMFEYCQAFSHWTYEWSN

GYLMIVDLQGV----GG--MLTDPQIHCLD--QNRFGLGNLGYSGFFKFFMTHQCNKFC
. ....|.|||    |    .||||||  |     || ||||  |. ||| |||||..|
HQMLVCDIQGVIHKNGDLYYYTDPQIHTEDQNGYGFGMGNLGQEGIEKFFQTHQCNQIC
Kinase 15771.AA Alpha-Unclassified 1340-1431 34 1.4e-30 96.81 In-house 111-215 (215) Show / Hide 
Range on Protein: 1340-1431
Range on HMM: 111-215/215
Sequence Identity: 34% (36 aa)

ENYIPGEYVKFNNNSG--WCDLKF-DEPGLLSQALSHFSYQVTEGYLMIVDLQG-VG------GMLTDPQIHCLDQNRFGL-GNLGYSGFFKFFMTH--Q
| |. ||.||..||.|     .|  .| . . .. .|..|| | . . ..|||| |.        .|||||| ..|  .|. .| |. . ...|  |  |
EPYLIGEFVKYSNNTGKEINFVKWEYEAYQYCCTYQHWTYQWTNHCDIVCDLQGWVDENDKKTWKMTDPQIHTIRQRYQGFKTNCGMRFIDYWFNNHHVQ

CNKFC
||..|
CNHYC
Kinase 15771.AA ChaK 1340-1431 36 3e-12 44.72 In-house 123-219 (219) Show / Hide 
Range on Protein: 1340-1431
Range on HMM: 123-219/219
Sequence Identity: 36% (35 aa)

ENYIPGEYVKFNNNSGWCDLKFDEPGLLSQALSHFSYQVTEGYLMIVDLQGVGGMLTDPQIHCLDQNR-----FGLGNLGYSGFFKFFMTHQCNKFC
|... ||. |.||| |   .       .  | ||. |  | | |...||||||  |||| .   .. .     ||  |||      |   | ||  |
EKCMTGEFRKYNNNNGDEIIPTNTLEEIMLAFSHWTYEYTRGELLVLDLQGVGENLTDPSVIKPEEKQSCDMVFGPANLGEDAIRNFRAKHHCNSCC