Gene 24053 (Tetrahymena)

24053

Species: Tetrahymena
Alias: PreTt24053, 3831.m01507, TTHERM_01090230, 228.m00045, 24053, 110
External Links: Tetrahymena Genome Database (TGD)
Annotation:

Classification

Group: Atypical
Family: Alpha
Subfamily: VWL

Sequence

Name Sequence Type Origin Length Description Download
24053.AA Protein None 842 None Fasta, JSON
24053.kin_dom Protein Kinase Domain None 124 None Fasta, JSON
24053.NA RNA None 2529 None Fasta, JSON

Protein domain

Protein domains of 24053.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
VWA 24053.AA VWA 69-245 14 0.000374 14.38 SMART 1-193 (193) Show / Hide 
Range on Protein: 69-245
Range on HMM: 1-193/193
Sequence Identity: 14% (30 aa)

SCDLAFVLDCTGSM-GSWIQRCKTQIINILNTLKQQFVNSTFRAGFVAYRDHCDTNRIEKFSFISSQYEALENFIGKLVA----TGGGDGPEDLAGGLYT
  |. ||.|..||| ....|. |. | .....|       . | | |.. |  |. ..  .   .. ...... | .|      .  . |. ... .| .
WLDIVFVIDGSGSMGPNNFQQVKQFI-KFVEQLD------GDRVGIVQFSD--DVRVEFPLN--YQDKDDVLKAIDNLQYKGKHDYFMGGGTNTG-ALQY

AIHE-LSWISKTKN--------------LFIIADAPCHGK-----KYHTTADDYPEGC--PKGVNIEGLIETLAKRNIELSVLEIN-----SSTNLMFSI
|. .  .. .. ..              . ...|   .        . ..|..  .    . .... .   .   | |     .       ........|
AMQNLFHERQG-RRGAGRPTKFWNVPKVIIVFTDGYSNDGPHDPEDIRKAARELRRSGVKIFVIGVGND-DM-ELRQIASCP-GEHHFFDVYDYDDLPDI

FQDIYKKTC
||.| .  |
FQHIIDWLC
Kinase 24053.AA ChaK 81-97 47 0.103213 2.86 In-house 1-17 (219) Show / Hide 
Range on Protein: 81-97
Range on HMM: 1-17/219
Sequence Identity: 47% (8 aa)

SMGSWIQRCKTQIINIL
|| || || ..  |..|
SMSSWSQRGRCAMIQFL
Kinase 24053.AA VWL 461-667 53 1.2e-141 424.88 In-house 1-206 (206) Show / Hide 
Range on Protein: 461-667
Range on HMM: 1-206/206
Sequence Identity: 53% (114 aa)

LTSKIQIYKKYFSEGAMRFAFYAYDTLLNQKLVAKLHKNWSDNS---NFEVMKRDSMSLIACHYFADEFNSRM--LLKTTDHDEVPILINFVDSSIYEVL
.  |..| .  |.|||||.|..| ||.||||.|||. |    .    | | |..|  | . | .   .||.|.    .||     . ..|||...||||.
IKTKVRISNIPFAEGAMRYAYHAKDTYLNQKMVAKQYKKQHKQNPKINKEDMIKDIESQFVCQHIVNCFNDRVSEHVQTT-----ANILNFVHCYIYEVT

RHYNKDIKYYFVENYIEGDYQKYNNNAGWTSSQESSQFNQISQAFSHFTWQYSQGQLLVVDIQGADLGVLTDPQIHTKNRSRFYGQGDLGYEGMLKFFHT
.|||..|||||||||||||||||||||||...... ..||.||||||||||||||....||.||...|.|||||||....|...|||.|||||||.||.|
HHYNHNIKYYFVENYIEGDYQKYNNNAGWCNQTDM-EYNQLSQAFSHFTWQYSQGYCMIVDLQGNEDGMLTDPQIHCLDQSHKFGQGNLGYEGMLRFFMT

HYCNEYCQRLNL
|.||.|||.|.|
HQCNKYCQKLQL
Kinase 24053.AA Alpha 461-662 44 6.9e-112 319.68 In-house 1-215 (215) Show / Hide 
Range on Protein: 461-662
Range on HMM: 1-215/215
Sequence Identity: 44% (96 aa)

LTSKIQIYKKYFSEGAMRFAFYAYDTLLNQKLVAKLHK--NWSDNSNFEVMKRDSMSLIACHYFADEFNSRMLLKTTDHDE----VPILINFVDSSIYEV
.  |||.  . |.||||| |..| |..|.||.|.|.||  . |.. . . ...|  . . ||.   |||.|                 ...||...|||.
QCTKIQMSSYPFMEGAMRYAMHAWDCWLHQKMVKKQHKKQWKSFKYVWHHWIKDVERQMVCHHCVREFNQRLWEQEYTTHFNQMKPQPIKQFVHCYIYEL

LRHYNKDIKYYFVENYIEGDYQKYNNNAGWTS-SQESSQFNQISQAFSHFTWQYSQGQLLVVDIQ-GADLGVLTDPQIHT---KNRSRFYGQGDLGYEGM
....|..||||.||||.||.||||||||||.. ......|||..|||||.|||||.|||.|||.| | ... |||||||.   ..... .|.|..|||||
IHCHNHNIKYYSVENYMEGEYQKYNNNAGWVDFLTDDNEFNQLMQAFSHWTWQYSNGQLMVVDLQWGVGEWKLTDPQIHCPAKLDQGMKFGDGNCGYEGM

LKFFHTH--YCNEYC
..||.||  .||.||
FRFFYTHHVQCNHYC
Kinase 24053.AA Alpha_kinase 472-662 34 1e-78 272.65 Pfam 1-225 (225) Show / Hide 
Range on Protein: 472-662
Range on HMM: 1-225/225
Sequence Identity: 34% (79 aa)

FSEGAMRFAFYAYDT-----LLNQKLVAKLHKN----WSD---NSNFEVMKRDSMSLIACHYFADEFNSRMLLKTTDHDEVPILINFVDSS-IYEVLRHY
|..|||| .|.. ||      .||..|||..|.    ...   . . . ...| .. . |......||..      .|.. |  |.|.|.. .||. .| 
FAQGAMRWCFRMFDTWDPNWRNNQNCVAKWYKKIKNYNQKQSIYVEEDYYFQDCKMQMICQQWMEKFNQKLQ----EHNNPPPPIEFYDCCIVYELEDHN

N-------------KDIKYYFVENYIEG-DYQKYNNNAGWT--SSQESSQFNQISQAFSHFTWQYSQGQLLVVDIQGAD-LG---VLTDPQIHTKNRSRF
.             . .||...|.|||| ...|||||.||.  . . ....||..|||||||...|.||..|.|||| .  .   .|||||||||. ...
KPDCYQGFFSYRTDWGGKYWYMEPYIEGCEFVKYNNNYGWVYDNMDRNDPWNQYMQAFSHFTYHRSNGQMMVCDIQGVGYNNKCYYLTDPQIHTKD-GNY

---Y--GQGDLGYEGMLKFFH-THYCNEYC
   .  |.|.||.||..|||. .| ||..|
EMDFDEGMGNLGQEGIEKFFQNQHKCNHIC
Alpha_kinase 24053.AA Alpha_kinase 453-662 27 2.7e-52 180.96 SMART 1-255 (255) Show / Hide 
Range on Protein: 453-662
Range on HMM: 1-255/255
Sequence Identity: 27% (73 aa)

NPSIKFQKLTSKIQIYKKYFSEGAMRFAFYAYDT-------LLNQKLVAKLHKNWSDNSN-----FE----VMKRDSMSLIACHYFADEFNSRMLLKTTD
. . . | ...|| . .| |..|||| .... |.       . ....|||..|  . ..      |.    .  ||     .| ..| |||.        
DNKWTCQETCVKI-KEPKPFAKGAMRWCYWGCDWSEHMHCFCHGWECVAKYFKKEYKRTWDEERYFHETLHLCLRDVEMQMMCKHWANEFNQ----EAQ-

HDEVPILINFVDSSIYEVL-----RHYNKDIKY----------------YFVENYIEGDYQKYNNNAGWTS-SQESS-------QFNQISQAFSHFTWQY
| . |  | |..... . .     .. ......                ...| ..||...||||| || . .. ..          .. |||||.|...
HNPCPKKIDFIPCYVFHFPRRIPAEYDRNIPYWFSYRTTDQMMVMCCCIFHMEPFMEGEFVKYNNNNGWVNDCMRWTTTSQRRTEMFEYCQAFSHWTYEW

SQGQLLVVDIQGA-----DLGVLTDPQIHTKNR-SRFYGQGDLGYEGMLKFFHTHYCNEYC
| .|.||.||||      || ..|||||||. .  ...|.| || ||. |||.||.||..|
SNHQMLVCDIQGVIHKNGDLYYYTDPQIHTEDQNGYGFGMGNLGQEGIEKFFQTHQCNQIC
Kinase 24053.AA Alpha-Unclassified 559-662 32 1.3e-29 93.61 In-house 101-215 (215) Show / Hide 
Range on Protein: 559-662
Range on HMM: 101-215/215
Sequence Identity: 32% (38 aa)

NKDIK-YYFVENYIEGDYQKYNNNAG--WTSSQESSQFNQISQAFSHFTWQYSQGQLLVVDIQG-AD-----LGVLTDPQIHTKNRSRFYG-QGDLGYEG
.| || .  || |..| . ||.|| |      . ..   |  ....|.|.| . ....|.| ||  |     .  .|||||||. |.|. |  .. |. .
DKNIKGCISVEPYLIGEFVKYSNNTGKEINFVKWEYEAYQYCCTYQHWTYQWTNHCDIVCDLQGWVDENDKKTWKMTDPQIHTI-RQRYQGFKTNCGMRF

MLKFFHTH--YCNEYC
. ..|  |   ||.||
IDYWFNNHHVQCNHYC
Kinase 24053.AA ChaK 567-662 34 1.7e-12 45.76 In-house 122-219 (219) Show / Hide 
Range on Protein: 567-662
Range on HMM: 122-219/219
Sequence Identity: 34% (34 aa)

VENYIEGDYQKYNNNAGWTSSQESSQFNQISQAFSHFTWQYSQGQLLVVDIQGADLGVLTDPQI----HTKNRSRFYGQGDLGYEGMLKFFHTHYCNEYC
.|... |.. ||||| |            |  ||||.|. |  | |||.|.||     |||| .      . .   .|   || . .  |   | ||  |
IEKCMTGEFRKYNNNNG-DEIIPTNTLEEIMLAFSHWTYEYTRGELLVLDLQGVG-ENLTDPSVIKPEEKQSCDMVFGPANLGEDAIRNFRAKHHCNSCC