13283

Species: Tetrahymena
Alias: TTHERM_00070930, 3707.m00317, 442, PreTt13283, 13283, 4.m00682
External Links: Tetrahymena Genome Database (TGD)
Annotation:

Classification

Group: Atypical
Family: HisK

Sequence

Name Sequence Type Origin Length Description Download
13283.AA Protein None 892 None Fasta, JSON
13283.kin_dom Protein Kinase Domain None 115 None Fasta, JSON
13283.NA RNA None 2679 None Fasta, JSON

Protein domain

Protein domains of 13283.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
HisKA 13283.AA HisKA 374-509 14 1.6e-10 42.16 SMART 1-89 (89) Show / Hide
Range on Protein: 374-509
Range on HMM: 1-89/89
Sequence Identity: 14% (22 aa)

YKDKLLATVSHDLKTPLNSIISITDYLQNDLTQSTCSTISEEQNSPKNFAQNQFNFSSVQDSSLGNQFNHFKSQSQTNQLYPLKKKNLKQFKNEDQQYSN
 |...||..||.|.|||..|.  .. ||... .                                                              | |  
AKRQFLANMSHELRTPLTAIRGYAELLQDWYYK--------------------------------------------------------------QRYHH

KINVSH---------------SKLLKIIYTNSMMLLQMINDILDYSQLNKS
. . ..                ..|..|.  .  ....|||.||.|..   
WTDLDPEQRLPMLRREFNCEYREYLETIQREADRMQRLINDLLDLSRIEAG

HisKA 13283.AA HisKA 374-405 41 1e-06 25.84 Pfam 1-34 (69) Show / Hide
Range on Protein: 374-405
Range on HMM: 1-34/69
Sequence Identity: 41% (14 aa)

YKDKLLATVSHDLKTPLNSIISITDYLQN--DLT
 | ..||..||.|.|||..|.  .. ||.  ||.
AKRQFLANMSHELRTPLTAIRGYAELLQDYTDLD

HisKA 13283.AA HisKA 481-509 27 0.003191 14.22 Pfam 41-69 (69) Show / Hide
Range on Protein: 481-509
Range on HMM: 41-69/69
Sequence Identity: 27% (8 aa)

KLLKIIYTNSMMLLQMINDILDYSQLNKS
..|..|.  .  ....|||.||.|..   
EYLETIQREAQRMQRLINDLLDFSRIEAG

Kinase 13283.AA HisK 559-673 35 9.2e-52 178.29 In-house 1-164 (164) Show / Hide
Range on Protein: 559-673
Range on HMM: 1-164/164
Sequence Identity: 35% (59 aa)

TDRNRLKQILMNFISNSLKFTLEG------FIKINIEQFE------------------------ESQNKIGISVEDSGVGMNTTIQKNLFKEFG------
.| ||.||||.|.|||.|||| .|      .|||..||..                        ...| | |||.|.|.||.  .||..|| ||      
SDPNRIKQILINLISNALKFTQKGGIPFQGYIKIKVEQINTQNNIKYNSIFIQKIQENMVQEQLQQKNLIQISVQDTGCGMPEEQQKKIFKMFGNIDDQH

-----TFNQYNL--NSNGIGLGLIICKKFIEIMSNY------SQIQVKSEEGKGTTFYFELNKY
     |||. |   |..|.||||.||..........       .|||.||.|||.||.|.... 
QMIKKTFNHQNKKNNQHGCGLGLTICNNLAKGLGPEHNQNGNRGIQVQSEVGKGSTFSFYIYNN

Kinase 13283.AA HATPase_c 559-673 30 4.5e-26 92.98 Pfam 1-120 (120) Show / Hide
Range on Protein: 559-673
Range on HMM: 1-120/120
Sequence Identity: 30% (38 aa)

TDRNRLKQILMNFISNSLKFTLE-GFIKINIEQFEESQNKIGISVEDSGVGMNT------TIQKNLFKEFGTFNQ--YNLNSNG--IGLGLIICKKFIEI
.|..||.|.. |...|..|.| | | |.. ... .   . . |.|||.|.|.          . ..|  |... .     .. |   |||| ||....| 
GDPDRLHQVVWNLVDNAIKHTPEGGHITVRVHRDD---DHVRITVEDNGPGIPPEMHSIAEDIPRIFEPFYRTDPDSR-RKYGGGLTGLGLYICRRIVEQ

MSNYSQIQVKSEEGKGTTFYFELNKY
.     |.| ||.|.|||| |.| . 
HGGT--IWVESEPGGGTTFTFTLPLE

Kinase 13283.AA HATPase_c 559-674 23 3.5e-23 84.24 SMART 1-130 (130) Show / Hide
Range on Protein: 559-674
Range on HMM: 1-130/130
Sequence Identity: 23% (34 aa)

TDRNRLKQILMNFISNSLKFTLE--------------GFIKINIEQFEESQNKIGISVEDSGVGMNT------TIQKNLFKEFGTFNQ---------YNL
.|..||.|.| | ..|..|.| |              | |.. ..          |.|||.|.|.         .....|  |... .          . 
GDPDRLRQVLWNLLDNAIKHTPEGHADPDLHDGKPGGGRITVRVH---------RITVEDNGPGIPPEMHKSIEDIPRIFEPFYRTDDSPSRMCPDSRSR

NSNG--IGLGLIICKKFIEIMSNYSQIQVKSEEGKGTTFYFELNKYI
.. |   |||| |||...| .    ...        |||.|.| . .
KYGGGLTGLGLSICKRIVEQHGGTIWVE--------TTFTFTLPLER

Kinase 13283.AA HisK 727-750 23 0.199063 1.79 In-house 82-119 (164) Show / Hide
Range on Protein: 727-750
Range on HMM: 82-119/164
Sequence Identity: 23% (9 aa)

SQENLNKLFKLSK--------------HTSDQNNQEGI
..|...|.||.                | . .|||.|.
PEEQQKKIFKMFGNIDDQHQMIKKTFNHQNKKNNQHGC

Response_reg 13283.AA Response_reg 807-870 24 1.1e-05 22.88 Pfam 1-64 (115) Show / Hide
Range on Protein: 807-870
Range on HMM: 1-64/115
Sequence Identity: 24% (16 aa)

MILIDDSQFNILSLKVNLREFSNEI-EIDEFVDPTKALNAIKNDSYDAILTDIQMPIISGIQLVQ
 ...||.. .   |.  |.. .  . ...|. |.  ||. ...  .| |..||.|| ..|..| .
VLIVDDHPLMREGLRQILEQ-KEGYEVVAEADDGEEALEWWQEHHPDLIIMDINMPGMDGLELCR