13760

Species: Tetrahymena
Alias: 866, 13760, 17.m00367, TTHERM_00202880, PreTt13760
External Links: Tetrahymena Genome Database (TGD)
Annotation:

Classification

Group: Atypical
Family: HisK

Sequence

Name Sequence Type Origin Length Description Download
13760.AA Protein None 770 None Fasta, JSON
13760.kin_dom Protein Kinase Domain None 113 None Fasta, JSON
13760.NA RNA None 2313 None Fasta, JSON

Protein domain

Protein domains of 13760.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
HisKA 13760.AA HisKA 305-369 24 9.6e-12 43.91 Pfam 1-69 (69) Show / Hide
Range on Protein: 305-369
Range on HMM: 1-69/69
Sequence Identity: 24% (17 aa)

YKDRLLATVSHDLKTPLNCIISLTGQIKE---MNIVS-IAQNVDIIYNNSLMLLFMIKDILDYSQIMHK
 | ..||..||.|.|||. |. ..  ...   ..    ... ...|.. .  .. .| |.||.|.| . 
AKRQFLANMSHELRTPLTAIRGYAELLQDYTDLDPEQMRREYLETIQREAQRMQRLINDLLDFSRIEAG

HisKA 13760.AA HisKA 305-369 19 4e-11 44.21 SMART 1-89 (89) Show / Hide
Range on Protein: 305-369
Range on HMM: 1-89/89
Sequence Identity: 19% (17 aa)

YKDRLLATVSHDLKTPLNCIISLTGQIKE------------MNIVSI------------AQNVDIIYNNSLMLLFMIKDILDYSQIMHK
 |...||..||.|.|||. |. ..  ...            ..   .            .. ...|.. .  .. .| |.||.|.| . 
AKRQFLANMSHELRTPLTAIRGYAELLQDWYYKQRYHHWTDLDPEQRLPMLRREFNCEYREYLETIQREADRMQRLINDLLDLSRIEAG

Kinase 13760.AA HisK 413-525 35 1.4e-61 210.92 In-house 1-164 (164) Show / Hide
Range on Protein: 413-525
Range on HMM: 1-164/164
Sequence Identity: 35% (59 aa)

NDKNRLKQIIINFVSNAIKFTKQG------FVTVKAVNQD---------------------------DCVRISVGDTGTGMSDEVVKKLFKEYE------
.|.||.|||.||..|||.|||..|      ....|. ...                           ....||| ||| ||..| .||.|| ..      
SDPNRIKQILINLISNALKFTQKGGIPFQGYIKIKVEQINTQNNIKYNSIFIQKIQENMVQEQLQQKNLIQISVQDTGCGMPEEQQKKIFKMFGNIDDQH

-----TFDNKDK-MNQQGIGLGLFICKNLVGALGPD------DCIKVESTVGLGSTFTFDIYKN
     ||....|  ||.|.|||| ||.||.. |||.      . |.|.|.|| ||||.| ||.|
QMIKKTFNHQNKKNNQHGCGLGLTICNNLAKGLGPEHNQNGNRGIQVQSEVGKGSTFSFYIYNN

Kinase 13760.AA HATPase_c 413-525 36 1.9e-29 104.74 Pfam 1-120 (120) Show / Hide
Range on Protein: 413-525
Range on HMM: 1-120/120
Sequence Identity: 36% (45 aa)

NDKNRLKQIIINFVSNAIKFTKQ-GFVTVKAVNQDDCVRISVGDTGTGMSD------EVVKKLFKEYETFDN-KDKMNQQG--IGLGLFICKNLVGALGP
.| .||.|.. |.|.||||.|.. | .||..  .|| |||.| |.| |...      |.. ..|  . ..|.  .  . .|   |||| ||. .| ..| 
GDPDRLHQVVWNLVDNAIKHTPEGGHITVRVHRDDDHVRITVEDNGPGIPPEMHSIAEDIPRIFEPFYRTDPDSR-RKYGGGLTGLGLYICRRIVEQHGG

DDCIKVESTVGLGSTFTFDIYKN
.  | |||..| |.|||| . . 
T--IWVESEPGGGTTFTFTLPLE

Kinase 13760.AA HATPase_c 413-526 27 1.2e-25 92.43 SMART 1-130 (130) Show / Hide
Range on Protein: 413-526
Range on HMM: 1-130/130
Sequence Identity: 27% (39 aa)

NDKNRLKQIIINFVSNAIKFTKQ--------------GFVTVKAVNQDDCVRISVGDTGTGMSD------EVVKKLFKEYETFDN--------KDKMNQQ
.| .||.|...| ..||||.|..              | .||..       ||.| |.| |...      |.....|  . ..|.         .  . .
GDPDRLRQVLWNLLDNAIKHTPEGHADPDLHDGKPGGGRITVRVH------RITVEDNGPGIPPEMHKSIEDIPRIFEPFYRTDDSPSRMCPDSRSRKYG

G--IGLGLFICKNLVGALGPDDCIKVESTVGLGSTFTFDIYKNE
|   |||| |||..| ..| .  |.||      .|||| . . .
GGLTGLGLSICKRIVEQHGGT--IWVE------TTFTFTLPLER

REC 13760.AA REC 647-765 19 9.4e-26 92.8 SMART 1-150 (150) Show / Hide
Range on Protein: 647-765
Range on HMM: 1-150/150
Sequence Identity: 19% (32 aa)

YNIIIVDDSK---YNLIALKI------YLNDYKNFD--------VEEFIHAE-------KALQRIKEQE-----------KKYDIVFTDLQMP-------
..| ||||..     .  .        .|    ...        |.|.  .|        ||....|..           ...|....|..||       
MRILIVDDDPAMAPVIREMLRNYTVIQRLLEKEGYENKMWMVEVVDEA-DGETLMNEIWEALELLQEHRDKKEDATTDQSEPPDLIIMDIMMPGDPFEDG

FMDGFELTKQIRQMQNRIQQPKIVIVTADSSDFLKIKSSQYAVNDYIEKPITDKDLFRSKI
 |||.||...||         .|...|| ... ....  .  ..||| ||....  .. .|
GMDGIELCRRIR---------PIIMLTAHDDEEDRVRALEAGADDYITKPFDPE-ELLARI

Response_reg 13760.AA Response_reg 649-766 32 1.8e-23 86.63 Pfam 1-115 (115) Show / Hide
Range on Protein: 649-766
Range on HMM: 1-115/115
Sequence Identity: 32% (39 aa)

IIIVDDSKYNLIALKIYLNDYKNF-DVEEFIHAEKALQRIKEQEKKYDIVFTDLQMPFMDGFELTKQI-RQMQNRIQQPKIVIVTADSSDFLKIKSSQYA
..||||.  .. .|. .|..   . .|.|.  .| ||...  ||...|....|..|| |||.||...| || . . | ..|...|| ........  |. 
VLIVDDHPLMREGLRQILEQKEGYEVVAEADDGEEALEWW--QEHHPDLIIMDINMPGMDGLELCRRIRRQHP-HPQ-TPIIMCTAHGDEDDAVEALQAG

VNDYIEKPITDKDLFRSKIM
 |||| ||. |.|  . .| 
ANDYITKPF-DPDELHAAIR