15301

Species: Tetrahymena
Alias: 215.m00044, 3809.m00215, TTHERM_01055470, 15301, PreTt15301, 251
External Links: Tetrahymena Genome Database (TGD)
Annotation:

Classification

Group: Atypical
Family: HisK

Sequence

Name Sequence Type Origin Length Description Download
15301.AA Protein None 1414 None Fasta, JSON
15301.kin_dom Protein Kinase Domain None 116 None Fasta, JSON
15301.NA RNA None 4245 None Fasta, JSON

Protein domain

Protein domains of 15301.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
PAS 15301.AA PAS 458-501 22 0.000837 15.14 Pfam 1-45 (120) Show / Hide
Range on Protein: 458-501
Range on HMM: 1-45/120
Sequence Identity: 22% (10 aa)

DFYNNMLNL-LPQGIVVVDSNKEMIYHNSSITKLLKCKPEQIMDQ
 .| ....  || .|.|.| . .. | |.......  ..|..| .
EHYRRIIENNLPDPIFVWDEDGWILYWNRAAERMFGWSREEVMGK

HisKA 15301.AA HisKA 759-824 34 1.2e-14 54.07 Pfam 1-69 (69) Show / Hide
Range on Protein: 759-824
Range on HMM: 1-69/69
Sequence Identity: 34% (24 aa)

CKMRMLASISHELRTPLNCSMTLLEVLKN-LVSNPLA--QEYIDPALNSQHLLLNIINDILDFAQIDVG
 | ..||..||||||||.  ....|.|..    .|    .||.. .... . ....|||.|||..|. |
AKRQFLANMSHELRTPLTAIRGYAELLQDYTDLDPEQMRREYLETIQREAQRMQRLINDLLDFSRIEAG

HisKA 15301.AA HisKA 759-824 25 6.4e-14 53.49 SMART 1-89 (89) Show / Hide
Range on Protein: 759-824
Range on HMM: 1-89/89
Sequence Identity: 25% (23 aa)

CKMRMLASISHELRTPLNCSMTLLEVLKN----------LVSNPLA-------------QEYIDPALNSQHLLLNIINDILDFAQIDVG
 | ..||..||||||||.  . ..|.|..             .|               .||.. .... . ....|||.||...|. |
AKRQFLANMSHELRTPLTAIRGYAELLQDWYYKQRYHHWTDLDPEQRLPMLRREFNCEYREYLETIQREADRMQRLINDLLDLSRIEAG

Kinase 15301.AA HisK 871-986 39 1.3e-59 204.37 In-house 1-164 (164) Show / Hide
Range on Protein: 871-986
Range on HMM: 1-164/164
Sequence Identity: 39% (65 aa)

SDPTRIRQIILNLLSNALKFTQKG------YIMIRVEKFN--------------------------ESLTKITVEDTGIGIASEDIQKIFEIFGK-----
||| ||.||..||.||||||||||      || | ||..|                          . | .|.|.|||.|.  |...|||..||.     
SDPNRIKQILINLISNALKFTQKGGIPFQGYIKIKVEQINTQNNIKYNSIFIQKIQENMVQEQLQQKNLIQISVQDTGCGMPEEQQKKIFKMFGNIDDQH

-----VDLKNNKLLNTQGAGLGLSIASQLARGLG------QNKKIEVLSELGKGSSFSFFLENK
      . ..||..|..|.||||.|. .||.|||      .|..|.| || ||||.|||...|.
QMIKKTFNHQNKKNNQHGCGLGLTICNNLAKGLGPEHNQNGNRGIQVQSEVGKGSTFSFYIYNN

Kinase 15301.AA HATPase_c 871-986 36 2.2e-26 94.07 Pfam 1-120 (120) Show / Hide
Range on Protein: 871-986
Range on HMM: 1-120/120
Sequence Identity: 36% (46 aa)

SDPTRIRQIILNLLSNALKFTQK-GYIMIRVEKFNESLTKITVEDTGIGIAS------EDIQKIFEIFGKVD-LKNNKLLNTQG--AGLGLSIASQLARG
 ||.|..|...||..||.|.|.. | | .||.. .     |||||.|.||.       |||..||| |...| .      ...|   ||||.|. .... 
GDPDRLHQVVWNLVDNAIKHTPEGGHITVRVHRDD-DHVRITVEDNGPGIPPEMHSIAEDIPRIFEPFYRTDPD--SR-RKYGGGLTGLGLYICRRIVEQ

LGQNKKIEVLSELGKGSSFSFFLENK
.|    |.| || |.|. |.| |  .
HGGT--IWVESEPGGGTTFTFTLPLE

Kinase 15301.AA HATPase_c 871-987 31 8.6e-26 92.92 SMART 1-130 (130) Show / Hide
Range on Protein: 871-987
Range on HMM: 1-130/130
Sequence Identity: 31% (45 aa)

SDPTRIRQIILNLLSNALKFTQK--------------GYIMIRVEKFNESLTKITVEDTGIGIAS------EDIQKIFEIFGKVD------LKNNKLLNT
 ||.|.||...|||.||.|.|..              | | .||.        |||||.|.||.       |||..||| |...|        ...  ..
GDPDRLRQVLWNLLDNAIKHTPEGHADPDLHDGKPGGGRITVRVH-------RITVEDNGPGIPPEMHKSIEDIPRIFEPFYRTDDSPSRMCPDSRSRKY

QG--AGLGLSIASQLARGLGQNKKIEVLSELGKGSSFSFFLENKL
.|   ||||||. .... .|    |.|       . |.| |  ..
GGGLTGLGLSICKRIVEQHGGT--IWVE------TTFTFTLPLER

REC 15301.AA REC 1255-1403 17 2e-17 65.12 SMART 1-150 (150) Show / Hide
Range on Protein: 1255-1403
Range on HMM: 1-150/150
Sequence Identity: 17% (32 aa)

PPVLVVDDN----EFNRYVLQ------KLLLTYNIQ--------HVQAQNGQ-------VAIDKVMQRYLKNVNNIDSQNNNFQINLPNLNSPVKCCCHF
. .|.|||.    . .| .|.      .||   ...         ..| .|.        |......   |.   . . . .                ..
MRILIVDDDPAMAPVIREMLRNYTVIQRLLEKEGYENKMWMVEVVDEA-DGETLMNEIWEALELLQEHRDKKEDATTD-QSE----------------PP

KIIFMDLDMP-------VKNGYEAVQEIKSFYIKNNLQKEAPIIVACTAFVGEEDKRKCEIYGMDYFLPKPISPKEIEKLL
 .|.||. ||         .|.|....|.              |...||. .|||....   |.| ...||..|.|. . .
DLIIMDIMMPGDPFEDGGMDGIELCRRIR-------------PIIMLTAHDDEEDRVRALEAGADDYITKPFDPEELLARI

Response_reg 15301.AA Response_reg 1331-1404 25 4.3e-12 45.88 Pfam 47-115 (115) Show / Hide
Range on Protein: 1331-1404
Range on HMM: 47-115/115
Sequence Identity: 25% (19 aa)

IIFMDLDMPVKNGYEAVQEI-KSFYIKNNLQKEAPIIVACTAFVGEEDKRKCEIYGMDYFLPKPISPKEIEKLLI
.|.||..||  .|.|. ..| .  . . .     . |..|||.  |.|. ..  .|......||..| |. . . 
LIIMDINMPGMDGLELCRRIRRQHP-HPQ-----TPIIMCTAHGDEDDAVEALQAGANDYITKPFDPDELHAAIR

Response_reg 15301.AA Response_reg 1257-1297 27 0.00399 13.76 Pfam 1-43 (115) Show / Hide
Range on Protein: 1257-1297
Range on HMM: 1-43/115
Sequence Identity: 27% (12 aa)

VLVVDDNEFNRYVLQKLLL-TYNIQHVQ-AQNGQVAIDKVMQR
||.|||.. .| .|...|   . .. |  |..|. |.... ..
VLIVDDHPLMREGLRQILEQKEGYEVVAEADDGEEALEWWQEH