Gene 19862 (Tetrahymena)

19862

Species: Tetrahymena
Alias: 3830.m00514, 68.m00151, TTHERM_00532040, 122, 19862, PreTt19862
External Links: Tetrahymena Genome Database (TGD)
Annotation:

Classification

Group: Atypical
Family: HisK

Sequence

Name Sequence Type Origin Length Description Download
19862.AA Protein None 1201 None Fasta, JSON
19862.kin_dom Protein Kinase Domain None 124 None Fasta, JSON
19862.NA RNA None 3606 None Fasta, JSON

Protein domain

Protein domains of 19862.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
HisKA 19862.AA HisKA 521-586 23 2.2e-13 51.7 SMART 1-89 (89) Show / Hide 
Range on Protein: 521-586
Range on HMM: 1-89/89
Sequence Identity: 23% (21 aa)

NKSQMLSQVAHEIRTPLNCVISMIEITKD----------LAEQSVC-------------ENFLAPALTSARLLNNLIQDLLDMAQVKAG
 |.|.|. ..||.||||. .. ..|. .|           . ..               . .|  .. .|. ...||.||||...  ||
AKRQFLANMSHELRTPLTAIRGYAELLQDWYYKQRYHHWTDLDPEQRLPMLRREFNCEYREYLETIQREADRMQRLINDLLDLSRIEAG
HisKA 19862.AA HisKA 521-586 30 2.3e-12 46.06 Pfam 1-69 (69) Show / Hide 
Range on Protein: 521-586
Range on HMM: 1-69/69
Sequence Identity: 30% (21 aa)

NKSQMLSQVAHEIRTPLNCVISMIEITKDLAEQSVCE---NFLAPALTSARLLNNLIQDLLDMAQVKAG
 |.|.|. ..||.||||. .. ..|. .| ....  .    .|  .. .|. ...||.||||...  ||
AKRQFLANMSHELRTPLTAIRGYAELLQDYTDLDPEQMRREYLETIQREAQRMQRLINDLLDFSRIEAG
Kinase 19862.AA HisK 633-756 37 7.4e-64 218.47 In-house 1-164 (164) Show / Hide 
Range on Protein: 633-756
Range on HMM: 1-164/164
Sequence Identity: 37% (61 aa)

SDPFRIRQILINLIGNALKFTQKG------FITVVAERYTYQNI----------------------DTIVRISVKDTGIGIKPKQKQKLFQAFGK-----
||| ||.|||||||.|||||||||      .|.. .| . .||.                      . ...|||.|||.|....|..|.|..||.     
SDPNRIKQILINLISNALKFTQKGGIPFQGYIKIKVEQINTQNNIKYNSIFIQKIQENMVQEQLQQKNLIQISVQDTGCGMPEEQQKKIFKMFGNIDDQH

-----LDDDNQEYLNPKGVGLGLMISNELAKKLSNPIF--TNQGLEVESVYGQGSQFSFFIIDN
      .. ... .|..|.||||.|.| |||.|.. ..   |.|..|.| .|.|| |||.| .|
QMIKKTFNHQNKKNNQHGCGLGLTICNNLAKGLGPEHNQNGNRGIQVQSEVGKGSTFSFYIYNN
Kinase 19862.AA HATPase_c 633-756 30 1.1e-23 84.69 Pfam 1-120 (120) Show / Hide 
Range on Protein: 633-756
Range on HMM: 1-120/120
Sequence Identity: 30% (41 aa)

SDPFRIRQILINLIGNALKFTQK-GFITVVAERYTYQNIDTIVRISVKDTGIGIKP------KQKQKLFQAFGKLDDDNQEYLNPKG--VGLGLMISNEL
 || |..|.. ||..||.|.|.. | ||| ..|         |||.|.|.|.|| |      .. ...|..|.. |.|     . .|   |||| |....
GDPDRLHQVVWNLVDNAIKHTPEGGHITVRVHRDD-----DHVRITVEDNGPGIPPEMHSIAEDIPRIFEPFYRTDPD-SR-RKYGGGLTGLGLYICRRI

AKKLSNPIFTNQGLEVESVYGQGSQFSFFIIDN
....         ..|||  |.|. |.| .   
VEQHGGT------IWVESEPGGGTTFTFTLPLE
Kinase 19862.AA HATPase_c 633-757 24 1.3e-21 79.07 SMART 1-130 (130) Show / Hide 
Range on Protein: 633-757
Range on HMM: 1-130/130
Sequence Identity: 24% (37 aa)

SDPFRIRQILINLIGNALKFTQK--------------GFITVVAERYTYQNIDTIVRISVKDTGIGIKP------KQKQKLFQAFGKLDD------DNQE
 || |.||.|.||..||.|.|..              | ||| ..           ||.|.|.|.|| |      .. ...|..|.. ||      ... 
GDPDRLRQVLWNLLDNAIKHTPEGHADPDLHDGKPGGGRITVRVH-----------RITVEDNGPGIPPEMHKSIEDIPRIFEPFYRTDDSPSRMCPDSR

YLNPKG--VGLGLMISNELAKKLSNPIFTNQGLEVESVYGQGSQFSFFIIDNV
  . .|   |||| |........   |  .            . |.| .   .
SRKYGGGLTGLGLSICKRIVEQHGGTIWVE------------TTFTFTLPLER
REC 19862.AA REC 1075-1197 23 1.3e-24 89.01 SMART 1-150 (150) Show / Hide 
Range on Protein: 1075-1197
Range on HMM: 1-150/150
Sequence Identity: 23% (38 aa)

KKILIVDDN----TFNVYALQ-----QLIKTLKQVE--------CDTSLSGE-------LAIELIKQKLTKNCCQS------YKIIFMDIDMP-------
..||||||.      .  .|.     |.. .    |        .|.  .||        |.||.... .|.  ..      . .|.||| ||       
MRILIVDDDPAMAPVIREMLRNYTVIQRLLEKEGYENKMWMVEVVDEA-DGETLMNEIWEALELLQEHRDKKEDATTDQSEPPDLIIMDIMMPGDPFEDG

QQSGLETTRIIRQNFLSSKETMIIGCSGYSNSQEYQNCIEAGMNDYLSKPIDKNLLKDML
  .|.|..| ||          || ...... .  . ..|||..||..||.| . | . .
GMDGIELCRRIR---------PIIMLTAHDDEEDRVRALEAGADDYITKPFDPEELLARI
Response_reg 19862.AA Response_reg 1077-1198 30 2.7e-23 86.01 Pfam 1-115 (115) Show / Hide 
Range on Protein: 1077-1198
Range on HMM: 1-115/115
Sequence Identity: 30% (37 aa)

ILIVDDNTFNVYALQQLIKTLKQV-ECDTSLSGELAIELIKQKLTKNCCQSYKIIFMDIDMPQQSGLETTRIIRQNFLSSKETMIIGCSGYSNSQEYQNC
.|||||.  .  .|.|....  .  ....  .|| |.|.. |...      . .|.|||.||  .|||..| ||..   . .| || |..... .  . .
VLIVDDHPLMREGLRQILEQKEGYEVVAEADDGEEALEWW-QEHH------PDLIIMDINMPGMDGLELCRRIRRQHP-HPQTPIIMCTAHGDEDDAVEA

IEAGMNDYLSKPIDKNLLKDMLE
..||.|||..||.|.. |.....
LQAGANDYITKPFDPDELHAAIR