Gene 22136 (Tetrahymena)

22136

Species: Tetrahymena
Alias: 630, PreTt22136, 3685.m00097, TTHERM_00600730, 83.m00205, 22136
External Links: Tetrahymena Genome Database (TGD)
Annotation:

Classification

Group: Atypical
Family: HisK

Sequence

Name Sequence Type Origin Length Description Download
22136.AA Protein None 1601 None Fasta, JSON
22136.kin_dom Protein Kinase Domain None 103 None Fasta, JSON
22136.NA RNA None 4806 None Fasta, JSON

Protein domain

Protein domains of 22136.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
HisKA 22136.AA HisKA 909-978 29 1.2e-10 40.04 Pfam 1-69 (69) Show / Hide 
Range on Protein: 909-978
Range on HMM: 1-69/69
Sequence Identity: 29% (21 aa)

RKMQLFGSLCHELRTPLNCSISFLDLYKQLKDGSEDEAD-VNEFIEPSLRSNQLMLNMVNDILDFVQMTEN
.| |.. .. |||||||.  . ...| .   ..  |. . . |..|  .|. | |....||.||| .. ..
AKRQFLANMSHELRTPLTAIRGYAELLQD--YTDLDPEQMRREYLETIQREAQRMQRLINDLLDFSRIEAG
HisKA 22136.AA HisKA 909-978 21 4.2e-09 37.48 SMART 1-89 (89) Show / Hide 
Range on Protein: 909-978
Range on HMM: 1-89/89
Sequence Identity: 21% (19 aa)

RKMQLFGSLCHELRTPLNCSISFLDLYKQ-------LKDGSEDEADV------------NEFIEPSLRSNQLMLNMVNDILDFVQMTEN
.| |.. .. |||||||.  . ...| .        ....  |. ..             |..|  .|. . |....||.||. .. ..
AKRQFLANMSHELRTPLTAIRGYAELLQDWYYKQRYHHWTDLDPEQRLPMLRREFNCEYREYLETIQREADRMQRLINDLLDLSRIEAG
Kinase 22136.AA HisK 1025-1167 32 3.3e-48 166.49 In-house 1-164 (164) Show / Hide 
Range on Protein: 1025-1167
Range on HMM: 1-164/164
Sequence Identity: 32% (58 aa)

SDPNRIRQIILNFLSNSLKFTKNFG-----TISLEAQGLEQANP---------QSQQ------IKQSSIVKVTVSDTGIGISKSNIKKIFEIFN------
||||||.||..|..||.||||.. |     .|.....  .. |.         ..|.      ..|. .....|.|||.|......||||..|.      
SDPNRIKQILINLISNALKFTQKGGIPFQGYIKIKVEQINTQNNIKYNSIFIQKIQENMVQEQLQQKNLIQISVQDTGCGMPEEQQKKIFKMFGNIDDQH

-----KTDHKDTSINPNGCGIGLPLSNSLAKLVGPL--QPIIIKENNGNQIQVQSGIQVDSVEGKGSSFSFLIQDL
     ...|.. . |..|||.||  .|.|||..||   |         |    . |||| | .||||.|||.|.. 
QMIKKTFNHQNKKNNQHGCGLGLTICNNLAKGLGPEHNQ---------N---GNRGIQVQSEVGKGSTFSFYIYNN
Kinase 22136.AA HATPase_c 1025-1168 19 5.8e-19 70.25 SMART 1-130 (130) Show / Hide 
Range on Protein: 1025-1168
Range on HMM: 1-130/130
Sequence Identity: 19% (34 aa)

SDPNRIRQIILNFLSNSLKFTKN-------------FGTISLEAQGLEQANPQSQQIKQSSIVKVTVSDTGIGISK------SNIKKIFEIFNKTDH---
 ||.|.||...| |.|..|.|.               |.|....                    .||.|.|.||..        |..||| | .||    
GDPDRLRQVLWNLLDNAIKHTPEGHADPDLHDGKPGGGRITVRVH------------------RITVEDNGPGIPPEMHKSIEDIPRIFEPFYRTDDSPS

----KDTSINPNG--CGIGLPLSNSLAKLVGPLQPIIIKENNGNQIQVQSGIQVDSVEGKGSSFSFLIQDLN
    . .| .  |   |.||......... |    | .                       . |.| .    
RMCPDSRSRKYGGGLTGLGLSICKRIVEQHGGT--IWVE----------------------TTFTFTLPLER
Kinase 22136.AA HATPase_c 1025-1127 26 3.7e-18 65.42 Pfam 1-98 (120) Show / Hide 
Range on Protein: 1025-1127
Range on HMM: 1-98/120
Sequence Identity: 26% (29 aa)

SDPNRIRQIILNFLSNSLKFTKNFGTISLEAQGLEQANPQSQQIKQSSIVKVTVSDTGIGISK------SNIKKIFEIFNKTDHKDTSINPNG--CGIGL
 ||.|..|...|...|..|.|.  |.|....   .              | .||.|.|.||..       .| .||| | .||   .  .  |   |.||
GDPDRLHQVVWNLVDNAIKHTPEGGHITVRVHRDD------------DHVRITVEDNGPGIPPEMHSIAEDIPRIFEPFYRTDPDSR-RKYGGGLTGLGL

PLSNSLAKLVG
 ... .....|
YICRRIVEQHG
Kinase 22136.AA HATPase_c 1148-1167 35 9.990658 1.29 Pfam 101-120 (120) Show / Hide 
Range on Protein: 1148-1167
Range on HMM: 101-120/120
Sequence Identity: 35% (7 aa)

IQVDSVEGKGSSFSFLIQDL
|.|.| .|.|. |.| .   
IWVESEPGGGTTFTFTLPLE
REC 22136.AA REC 1464-1590 18 5.1e-21 77.07 SMART 1-150 (150) Show / Hide 
Range on Protein: 1464-1590
Range on HMM: 1-150/150
Sequence Identity: 18% (30 aa)

TKILIADDS----GFNIMVLK------KIIQLFHIQ-------NIHICHDGQ-------EAVTKVRDILNNPKERL------YDMIFMDLDMP-------
 .|||.||.      . ..|.      .. .   ..       ..... ||.       ||. ...    .  . .      .| |.||. ||       
MRILIVDDDPAMAPVIREMLRNYTVIQRLLEKEGYENKMWMVEVVDEA-DGETLMNEIWEALELLQEHRDKKEDATTDQSEPPDLIIMDIMMPGDPFEDG

IMNGYEACKQIKQLIQNYEVSDQLYIIACSAYGVQVKEEHAFHISQLDDAIAKPVKKDQIQYVL
 |.|.|.|..|.             ||...|..     ..|.  .  || | ||.. .... ..
GMDGIELCRRIR------------PIIMLTAHDDEEDRVRAL-EAGADDYITKPFDPEELLARI
Response_reg 22136.AA Response_reg 1466-1591 25 1.2e-15 58.67 Pfam 1-115 (115) Show / Hide 
Range on Protein: 1466-1591
Range on HMM: 1-115/115
Sequence Identity: 25% (33 aa)

ILIADDSGFNIMVLKKIIQ-LFHIQNIHICHDGQEAVTKVRDILNNPKERLYDMIFMDLDMPIMNGYEACKQI-KQLIQNYEVSDQLYIIACSAYGVQVK
.||.||.  . ..|..|..    ....  . ||.||. ..      .... .|.|.||..|| |.|.|.|..| .|.   ..    . ||.|.|.|    
VLIVDDHPLMREGLRQILEQKEGYEVVAEADDGEEALEWW------QEHH-PDLIIMDINMPGMDGLELCRRIRRQHP-HPQ----TPIIMCTAHGDEDD

EEHAFHISQLDDAIAKPVKKDQIQYVLQ
 ..|.     .| |.||...|..   ..
AVEALQAG-ANDYITKPFDPDELHAAIR