26487

Species: Tetrahymena
Alias: PreTt26487, 3831.m01588, TTHERM_00433440, 48.m00250, 106, 26487
External Links: Tetrahymena Genome Database (TGD)
Annotation:

Classification

Group: Atypical
Family: HisK

Sequence

Name Sequence Type Origin Length Description Download
26487.AA Protein None 781 None Fasta, JSON
26487.kin_dom Protein Kinase Domain None 114 None Fasta, JSON
26487.NA RNA None 2346 None Fasta, JSON

Protein domain

Protein domains of 26487.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
HisKA 26487.AA HisKA 337-403 28 1.3e-10 39.94 Pfam 1-69 (69) Show / Hide
Range on Protein: 337-403
Range on HMM: 1-69/69
Sequence Identity: 28% (20 aa)

YKDKLLARISHDLKTPLNCILSISQNFKNHLSNISSFQ---NDMDIISKNSQLLMHMINDILDYSQIKMQ
 | ..|| .||.|.|||. |.  ..  ..  .. .. |      ..| . .| . ..|||.||.|.|  .
AKRQFLANMSHELRTPLTAIRGYAELLQD-YTDLDPEQMRREYLETIQREAQRMQRLINDLLDFSRIEAG

HisKA 26487.AA HisKA 337-403 21 3.1e-10 41.27 SMART 1-89 (89) Show / Hide
Range on Protein: 337-403
Range on HMM: 1-89/89
Sequence Identity: 21% (19 aa)

YKDKLLARISHDLKTPLNCILSISQNFKN-----------HLSNISS-----------FQNDMDIISKNSQLLMHMINDILDYSQIKMQ
 |...|| .||.|.|||. |.  ..  ..            |.               ..   ..| . .. . ..|||.||.|.|  .
AKRQFLANMSHELRTPLTAIRGYAELLQDWYYKQRYHHWTDLDPEQRLPMLRREFNCEYREYLETIQREADRMQRLINDLLDLSRIEAG

Kinase 26487.AA HisK 448-561 28 8e-46 158.56 In-house 1-164 (164) Show / Hide
Range on Protein: 448-561
Range on HMM: 1-164/164
Sequence Identity: 28% (47 aa)

NDENRFKQVILNFIQNSIQYT------PSGFIKVKCQRIDLT-------------------------NELQVSIIDTGKGMDQETIDRLFCKIG------
.|.||.||...|.|.|.. .|      ..|.||.| . |. .                         | .|.|..||| ||..|..  .| . |      
SDPNRIKQILINLISNALKFTQKGGIPFQGYIKIKVEQINTQNNIKYNSIFIQKIQENMVQEQLQQKNLIQISVQDTGCGMPEEQQKKIFKMFGNIDDQH

-----TFNKTHL--NVDGVGLGLIMSKKLIGFIGHK------SSIQVESKLLQGSTFTFSIRQN
     |||. .   |  |.||||.....|....|..       .|||.|.  .||||.| |..|
QMIKKTFNHQNKKNNQHGCGLGLTICNNLAKGLGPEHNQNGNRGIQVQSEVGKGSTFSFYIYNN

Kinase 26487.AA HATPase_c 448-561 28 3.4e-23 82.98 Pfam 1-120 (120) Show / Hide
Range on Protein: 448-561
Range on HMM: 1-120/120
Sequence Identity: 28% (36 aa)

NDENRFKQVILNFIQNSIQYTPS-GFIKVKCQRIDLTNELQVSIIDTGKGMDQ------ETIDRLFCKIGTFNK--THLNVDG--VGLGLIMSKKLIGFI
.|..|..||..|.. |.|..||. | |.|.. | |  ........|.|.|..       | |.|.| . ... .  .  .. |   |||| ......   
GDPDRLHQVVWNLVDNAIKHTPEGGHITVRVHRDD--DHVRITVEDNGPGIPPEMHSIAEDIPRIFEPFYRTDPDSR-RKYGGGLTGLGLYICRRIVEQH

GHKSSIQVESKLLQGSTFTFSIRQN
| .  |.|||.  .|.|||| .   
GGT--IWVESEPGGGTTFTFTLPLE

Kinase 26487.AA HATPase_c 448-562 24 3.5e-21 77.63 SMART 1-130 (130) Show / Hide
Range on Protein: 448-562
Range on HMM: 1-130/130
Sequence Identity: 24% (34 aa)

NDENRFKQVILNFIQNSIQYTPSGF-------IKVKCQRIDLTNELQVSIIDTGKGMDQ------ETIDRLFCKIGTFNK---------THLNVDG--VG
.|..|..||..| ..|.|..||.|.        |  . ||... . .....|.|.|...      | |.|.| . ... .         .  .. |   |
GDPDRLRQVLWNLLDNAIKHTPEGHADPDLHDGKPGGGRITVRVH-RITVEDNGPGIPPEMHKSIEDIPRIFEPFYRTDDSPSRMCPDSRSRKYGGGLTG

LGLIMSKKLIGFIGHKSSIQVESKLLQGSTFTFSIRQNL
|||  .|...   | .  |.||      .||||...  .
LGLSICKRIVEQHGGT--IWVE------TTFTFTLPLER

REC 26487.AA REC 658-774 17 3e-13 51.28 SMART 1-150 (150) Show / Hide
Range on Protein: 658-774
Range on HMM: 1-150/150
Sequence Identity: 17% (28 aa)

LKVMIVDDI----YYNIIALK------AYLKNFTNL-------EISEFIFAE-------DAFLEIQKN-------------QYDIIFSDIQMP-------
....||||       .  .|.      ..|.            .. |.  .|       .|.  .|..             ..|.|. ||.||       
MRILIVDDDPAMAPVIREMLRNYTVIQRLLEKEGYENKMWMVEVVDEA-DGETLMNEIWEALELLQEHRDKKEDATTDQSEPPDLIIMDIMMPGDPFEDG

IMDGIEFITKVRLLKDKIKQPIVFMISADNQQAHEERLRDLEIQSFIQKPILNQQSFNNLV
 |||||.. ..|          . |..| .. .. .| ...    .| ||.  .  .   .
GMDGIELCRRIR---------PIIMLTAHDDEEDRVRALEAGADDYITKPFDPE-ELLARI

Response_reg 26487.AA Response_reg 660-764 26 1.3e-10 40.56 Pfam 1-105 (115) Show / Hide
Range on Protein: 660-764
Range on HMM: 1-105/115
Sequence Identity: 26% (28 aa)

VMIVDDIYYNIIALKAYLKNFTNL-EISEFIFAEDAFLEIQKNQYDIIFSDIQMPIMDGIEFITKVRLLKDKIKQPIVFMISADNQQAHEERLRDLEIQS
|.||||   .  .|. .|..   . .. |.  .|.|   .|....|.|. ||.|| |||.|.... |  ..   |. . |..| .. .  ..  .. .  
VLIVDDHPLMREGLRQILEQKEGYEVVAEADDGEEALEWWQEHHPDLIIMDINMPGMDGLELCRRIRRQHP-HPQTPIIMCTAHGDEDDAVEALQAGAND

FIQKPI
.| ||.
YITKPF