3209

Species: Tetrahymena
Alias: 69.m00251, 3718.m00112, PreTt03209, 3209, 1105, TTHERM_00537230
External Links: Tetrahymena Genome Database (TGD)
Annotation:

Classification

Group: Atypical
Family: HisK

Sequence

Name Sequence Type Origin Length Description Download
3209.AA Protein None 1403 None Fasta, JSON
3209.kin_dom Protein Kinase Domain None 121 None Fasta, JSON
3209.NA RNA None 4212 None Fasta, JSON

Protein domain

Protein domains of 3209.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
HisKA 3209.AA HisKA 740-814 32 1e-06 26.15 Pfam 1-69 (69) Show / Hide
Range on Protein: 740-814
Range on HMM: 1-69/69
Sequence Identity: 32% (24 aa)

YKIKMLSSISHELKTPLNCCMGMLDDVLNLISNENFGDLEISQKIRESLEPAQQSNQLLLYMIRDLIDLGTFELV
 | ..|...||||.|||.  .|...  ..      ..||   | .|| || .|.. | .. .|.|| |.   |  
AKRQFLANMSHELRTPLTAIRGYAELLQD------YTDLDPEQMRREYLETIQREAQRMQRLINDLLDFSRIEAG

HisKA 3209.AA HisKA 740-814 25 5e-05 21.42 SMART 1-89 (89) Show / Hide
Range on Protein: 740-814
Range on HMM: 1-89/89
Sequence Identity: 25% (24 aa)

YKIKMLSSISHELKTPLNCCMGMLDDVLNLISNENF--------GDLEISQK-----------IRESLEPAQQSNQLLLYMIRDLIDLGTFELV
 | ..|...||||.|||.  .|...     .  ...        .||   |            .|| || .|.. . .. .|.|| ||   |  
AKRQFLANMSHELRTPLTAIRGYAE-----LLQDWYYKQRYHHWTDLDPEQRLPMLRREFNCEYREYLETIQREADRMQRLINDLLDLSRIEAG

Kinase 3209.AA HisK 862-982 31 4.2e-51 176.08 In-house 1-164 (164) Show / Hide
Range on Protein: 862-982
Range on HMM: 1-164/164
Sequence Identity: 31% (51 aa)

SDENRVRSIVVNFLTNSLKFTQRNG-----KITVKAELTG--------------------------NNNAKISVEDNGIGIPQKKLSEIFKFYNKSD---
||.||.. |..|...|.||||| .|     .|..|.|.                            .|. .|||.| |.|.|.... .|||.... |   
SDPNRIKQILINLISNALKFTQKGGIPFQGYIKIKVEQINTQNNIKYNSIFIQKIQENMVQEQLQQKNLIQISVQDTGCGMPEEQQKKIFKMFGNIDDQH

-----MFISKNQ--ITQGIGIGLSVSYKLAQGLTIEEY--KNQPIQVKSEEKKGSIFCFVLKNQ
     .|. .|.   ..|.|.||.....||.||  |..  .|..|||.||..|||.| |.. |.
QMIKKTFNHQNKKNNQHGCGLGLTICNNLAKGLGPEHNQNGNRGIQVQSEVGKGSTFSFYIYNN

Kinase 3209.AA HATPase_c 862-982 27 3e-25 90.12 Pfam 1-120 (120) Show / Hide
Range on Protein: 862-982
Range on HMM: 1-120/120
Sequence Identity: 27% (36 aa)

SDENRVRSIVVNFLTNSLKFTQRNGKITVKAELTGNNNAKISVEDNGIGIPQ------KKLSEIFKFYNKSDMFISKNQITQG--IGIGLSVSYKLAQGL
 |..|.. .| |...|..|.|. .|.|||... .. ..  |.|||||.|||       .... ||  . ..|   |  . ..|   |.||........ .
GDPDRLHQVVWNLVDNAIKHTPEGGHITVRVHRDD-DHVRITVEDNGPGIPPEMHSIAEDIPRIFEPFYRTDPD-SR-RKYGGGLTGLGLYICRRIVEQH

TIEEYKNQPIQVKSEEKKGSIFCFVLKNQ
  .      |.| ||...|. | | |. .
GGT------IWVESEPGGGTTFTFTLPLE

Kinase 3209.AA HATPase_c 862-983 23 5.6e-23 83.59 SMART 1-130 (130) Show / Hide
Range on Protein: 862-983
Range on HMM: 1-130/130
Sequence Identity: 23% (35 aa)

SDENRVRSIVVNFLTNSLKFTQR-------------NGKITVKAELTGNNNAKISVEDNGIGIPQ------KKLSEIFKFYNKSDMFI------SKNQIT
 |..|.| .. | |.|..|.|.              .|.|||...        |.|||||.|||.      .... ||  . . | ..      |... .
GDPDRLRQVLWNLLDNAIKHTPEGHADPDLHDGKPGGGRITVRVH-------RITVEDNGPGIPPEMHKSIEDIPRIFEPFYRTDDSPSRMCPDSRSRKY

QG--IGIGLSVSYKLAQGLTIEEYKNQPIQVKSEEKKGSIFCFVLKNQD
.|   |.|||.. .... .  .      |.|       . |.| |. . 
GGGLTGLGLSICKRIVEQHGGT------IWVE------TTFTFTLPLER

REC 3209.AA REC 1275-1397 26 3.3e-33 117.56 SMART 1-150 (150) Show / Hide
Range on Protein: 1275-1397
Range on HMM: 1-150/150
Sequence Identity: 26% (44 aa)

GQILIVDDI----QFNLLMLS------NLLKRYQMK--------VDLAHDGQ-------EAVNKVQEK--------YQKQKETYQIIFMDIQMP------
  ||||||     . .. ||.      .||..  .         || | ||.       ||....||.           |.| ...|.|||.||      
MRILIVDDDPAMAPVIREMLRNYTVIQRLLEKEGYENKMWMVEVVDEA-DGETLMNEIWEALELLQEHRDKKEDATTD-QSEPPDLIIMDIMMPGDPFED

-IMDGFQATKEIRKFLQQKNASQIPIIAVSAFGDQQFKEQSKKVGMTDYIEKPVQTIKLDKAF
  |||......||           |||...|..| . ...  ..|. ||| ||..   | .. 
GGMDGIELCRRIR-----------PIIMLTAHDDEEDRVRALEAGADDYITKPFDPEELLARI

Response_reg 3209.AA Response_reg 1277-1398 32 9.2e-29 105.59 Pfam 1-115 (115) Show / Hide
Range on Protein: 1277-1398
Range on HMM: 1-115/115
Sequence Identity: 32% (40 aa)

ILIVDDIQFNLLMLSNLLK-RYQM-KVDLAHDGQEAVNKVQEKYQKQKETYQIIFMDIQMPIMDGFQATKEIRKFLQ-QKNASQIPIIAVSAFGDQQFKE
.||||| . ..  | ..|. .... .|..| ||.||....||.       . .|.|||.|| |||......||. ..  .    .|||...|.|| . ..
VLIVDDHPLMREGLRQILEQKEGYEVVAEADDGEEALEWWQEHH------PDLIIMDINMPGMDGLELCRRIRRQHPHPQ----TPIIMCTAHGDEDDAV

QSKKVGMTDYIEKPVQTIKLDKAFL
.  ..|. ||| ||.   .| .|  
EALQAGANDYITKPFDPDELHAAIR