Gene 4145 (Tetrahymena)

4145

Species: Tetrahymena
Alias: 4145, PreTt04145, 1115, 80.m00191, TTHERM_00585390, 3675.m00089
External Links: Tetrahymena Genome Database (TGD)
Annotation:

Classification

Group: Atypical
Family: HisK

Sequence

Name Sequence Type Origin Length Description Download
4145.AA Protein None 920 None Fasta, JSON
4145.kin_dom Protein Kinase Domain None 106 None Fasta, JSON
4145.NA RNA None 2763 None Fasta, JSON

Protein domain

Protein domains of 4145.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
HisKA 4145.AA HisKA 179-246 31 2.3e-08 32.11 Pfam 1-69 (69) Show / Hide 
Range on Protein: 179-246
Range on HMM: 1-69/69
Sequence Identity: 31% (22 aa)

FKKKILSSVSHELQTPLNCSIQLLEILQNSDILQETQ-KKMFVTPTLNSNQLLMYMINDIIDFAQIADG
 |.. |...|||| |||.  . ..|.||... | . |  . ..   ... | .  .|||. ||..|  |
AKRQFLANMSHELRTPLTAIRGYAELLQDYTDLDPEQMRREYLETIQREAQRMQRLINDLLDFSRIEAG
HisKA 4145.AA HisKA 179-246 22 1.2e-07 32.64 SMART 1-89 (89) Show / Hide 
Range on Protein: 179-246
Range on HMM: 1-89/89
Sequence Identity: 22% (20 aa)

FKKKILSSVSHELQTPLNCSIQLLEILQN---------SDILQETQK------------KMFVTPTLNSNQLLMYMINDIIDFAQIADG
 | . |...|||| |||.  . ..|.||.         .. |.. |             . ..   ... . .  .|||. |...|  |
AKRQFLANMSHELRTPLTAIRGYAELLQDWYYKQRYHHWTDLDPEQRLPMLRREFNCEYREYLETIQREADRMQRLINDLLDLSRIEAG
Kinase 4145.AA HisK 293-398 32 6e-45 155.65 In-house 1-164 (164) Show / Hide 
Range on Protein: 293-398
Range on HMM: 1-164/164
Sequence Identity: 32% (54 aa)

SDPMRLKQVVINLIR---------------FISVNLD--------------------------LEDENLIKISIQDTGCGIPSQLGSNIFKGVED-----
|||.|.||..||||                .|.....                          |...|||.||.||||||.| ..  .|||  .      
SDPNRIKQILINLISNALKFTQKGGIPFQGYIKIKVEQINTQNNIKYNSIFIQKIQENMVQEQLQQKNLIQISVQDTGCGMPEEQQKKIFKMFGNIDDQH

-----YKNIQQKFN-TKGAGLGLTIANNIAMGLG------DNRKIEYTSQVDVGSVFTFFVLNR
     ..| |.|.| ..|.||||||.||.|.|||      .||.|.  |.|..|| |.|...|.
QMIKKTFNHQNKKNNQHGCGLGLTICNNLAKGLGPEHNQNGNRGIQVQSEVGKGSTFSFYIYNN
Kinase 4145.AA HATPase_c 309-398 23 1e-09 36.02 Pfam 27-120 (120) Show / Hide 
Range on Protein: 309-398
Range on HMM: 27-120/120
Sequence Identity: 23% (25 aa)

ISVNLDLEDENLIKISIQDTGCGIPS------QLGSNIFK-------GVEDYKNIQQKFNTKG--AGLGLTIANNIAMGLGDNRKIEYTSQVDVGSVFTF
|.| .. .| . . |...|.|.|||       .. ..||                    ...|   ||||.|.. |.  .|    |...|... |..|||
ITVRVHRDD-DHVRITVEDNGPGIPPEMHSIAEDIPRIFEPFYRTDPD-------SR-RKYGGGLTGLGLYICRRIVEQHGGT--IWVESEPGGGTTFTF

FVLNR
 .  .
TLPLE
Kinase 4145.AA HATPase_c 293-399 20 1e-06 29.56 SMART 1-130 (130) Show / Hide 
Range on Protein: 293-399
Range on HMM: 1-130/130
Sequence Identity: 20% (29 aa)

SDPMRLKQVVINL----IRFISV---------------NLDLEDENLIKISIQDTGCGIPS------QLGSNIFKGVEDYKN-------IQQKFNTKG--
 ||.||.||..||    |..                   .... .    |...|.|.|||       .. ..||      ..        ..  ...|  
GDPDRLRQVLWNLLDNAIKHTPEGHADPDLHDGKPGGGRITVRVH---RITVEDNGPGIPPEMHKSIEDIPRIFEPFYRTDDSPSRMCPDSRSRKYGGGL

AGLGLTIANNIAMGLGDNRKIEYTSQVDVGSVFTFFVLNRS
 ||||.|...|.  .|    |...      ..||| .  . 
TGLGLSICKRIVEQHGGT--IWVE------TTFTFTLPLER
Kinase 4145.AA HATPase_c 293-306 64 0.814058 5.08 Pfam 1-14 (120) Show / Hide 
Range on Protein: 293-306
Range on HMM: 1-14/120
Sequence Identity: 64% (9 aa)

SDPMRLKQVVINLI
 || ||.||| ||.
GDPDRLHQVVWNLV
REC 4145.AA REC 790-915 26 1.4e-26 95.56 SMART 1-150 (150) Show / Hide 
Range on Protein: 790-915
Range on HMM: 1-150/150
Sequence Identity: 26% (43 aa)

PKILIVDDN----PFNLFALE------LRLKEYSYE--------VDKANSGM-------EAIEKVKNRYNNQKSCC----KQYKLIFMDIDMP-------
..||||||.    | .. .|.      . |..  ||        || | .|        ||.|....   .. .      ... ||.||| ||       
MRILIVDDDPAMAPVIREMLRNYTVIQRLLEKEGYENKMWMVEVVDEA-DGETLMNEIWEALELLQEHRDKKEDATTDQSEPPDLIIMDIMMPGDPFEDG

QKNGYETTLEIFDFFNSINEKCCPISACTAYVQEEEKKKAFNTGMSYYLTKPVLSEKLLKIL
  .|.|.. .|            || ..||. .|| . .|.  |.  |.|||.  | ||. .
GMDGIELCRRIR-----------PIIMLTAHDDEEDRVRALEAGADDYITKPFDPEELLARI
Response_reg 4145.AA Response_reg 792-916 29 7.1e-20 73.76 Pfam 1-115 (115) Show / Hide 
Range on Protein: 792-916
Range on HMM: 1-115/115
Sequence Identity: 29% (38 aa)

ILIVDDNPFNLFALELRLK-EYSY-EVDKANSGMEAIEKVKNRYNNQKSCCKQYKLIFMDIDMPQKNGYETTLEI-FDFFNSINEKCCPISACTAYVQEE
.|||||.| .. .|   |. .. | .|. | .| ||.|.....          . ||.|||.||  .|.|.. .|      . .   .|| .|||. .|.
VLIVDDHPLMREGLRQILEQKEGYEVVAEADDGEEALEWWQEHH---------PDLIIMDINMPGMDGLELCRRIRRQHP-HPQ---TPIIMCTAHGDED

EKKKAFNTGMSYYLTKPVLSEKLLKILI
 . .|.  |. .|.|||.  ..|.... 
DAVEALQAGANDYITKPFDPDELHAAIR