Gene 6574 (Tetrahymena)

6574

Species: Tetrahymena
Alias: 89.m00168, 1050, 6574, TTHERM_00630610, PreTt06574, 3831.m01469
External Links: Tetrahymena Genome Database (TGD)
Annotation:

Classification

Group: Atypical
Family: HisK

Sequence

Name Sequence Type Origin Length Description Download
6574.AA Protein None 1459 None Fasta, JSON
6574.kin_dom Protein Kinase Domain None 59 None Fasta, JSON
6574.NA RNA None 4380 None Fasta, JSON

Protein domain

Protein domains of 6574.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
HisKA 6574.AA HisKA 696-766 31 2e-11 42.78 Pfam 1-69 (69) Show / Hide 
Range on Protein: 696-766
Range on HMM: 1-69/69
Sequence Identity: 31% (23 aa)

EKMKIFATLSHELRTPLNCSISMLEVLKD--ELSQEEQNKFCIEEYIVPALFSNKLLLNQINDILDYVQMDCG
.| . .|..||||||||.  . ..|.|.|  .|. |..    ..||.  .. . . ....|||.||. ... |
AKRQFLANMSHELRTPLTAIRGYAELLQDYTDLDPEQM----RREYLETIQREAQRMQRLINDLLDFSRIEAG
HisKA 6574.AA HisKA 696-766 25 2.4e-10 41.61 SMART 1-89 (89) Show / Hide 
Range on Protein: 696-766
Range on HMM: 1-89/89
Sequence Identity: 25% (23 aa)

EKMKIFATLSHELRTPLNCSISMLEVLKD-----------ELSQEEQNKFC-------IEEYIVPALFSNKLLLNQINDILDYVQMDCG
.| . .|..||||||||.  . ..|.|.|           .|. |.. .         ..||.  .. . . ....|||.||. ... |
AKRQFLANMSHELRTPLTAIRGYAELLQDWYYKQRYHHWTDLDPEQRLPMLRREFNCEYREYLETIQREADRMQRLINDLLDLSRIEAG
Kinase 6574.AA HisK 813-934 35 9.7e-56 191.49 In-house 1-164 (164) Show / Hide 
Range on Protein: 813-934
Range on HMM: 1-164/164
Sequence Identity: 35% (59 aa)

SDQNRIRQILLNFLSNSLKFTKSG------YIELGFNQIC--------------------------QNIYQLYVKDSGIGISKENQKKIFDFCNKIQ---
||.|||.|||.|..||.||||. |      ||.. ..||                           .|..| .|.|.|.|...|.|||||.....|.   
SDPNRIKQILINLISNALKFTQKGGIPFQGYIKIKVEQINTQNNIKYNSIFIQKIQENMVQEQLQQKNLIQISVQDTGCGMPEEQQKKIFKMFGNIDDQH

-----YENKEEEQLNNQGCGLGLLISNSLAKGLVTDKT--RNGGISVESEYGIGSKFSILVEDL
     . |......| .|||||| |.|.|||||  ..    |.||.|.||.|.||.||..... 
QMIKKTFNHQNKKNNQHGCGLGLTICNNLAKGLGPEHNQNGNRGIQVQSEVGKGSTFSFYIYNN
Kinase 6574.AA HATPase_c 813-934 22 1.3e-15 56.53 Pfam 1-120 (120) Show / Hide 
Range on Protein: 813-934
Range on HMM: 1-120/120
Sequence Identity: 22% (31 aa)

SDQNRIRQILLNFLSNSLKFTKS-GYIELGFNQICQNIYQLYVKDSGIGISK------ENQKKIFD-------FCNKIQYENKEEEQLNNQG--CGLGLL
 |..|..|...|...|..|.|.. | |..   .   .  .. |.|.|.||..      |.. .||.                      . .|   |||| 
GDPDRLHQVVWNLVDNAIKHTPEGGHITVRVHRDD-DHVRITVEDNGPGIPPEMHSIAEDIPRIFEPFYRTDPD----------SR-RKYGGGLTGLGLY

ISNSLAKGLVTDKTRNGGISVESEYGIGSKFSILVEDL
|.. ... .  .      |.|||| | |..|.. .   
ICRRIVEQHGGT------IWVESEPGGGTTFTFTLPLE
Kinase 6574.AA HATPase_c 813-935 20 1.2e-12 49.27 SMART 1-130 (130) Show / Hide 
Range on Protein: 813-935
Range on HMM: 1-130/130
Sequence Identity: 20% (30 aa)

SDQNRIRQILLNFLSNSLKFTKS--------------GYIELGFNQICQNIYQLYVKDSGIGISK------ENQKKIFDFCNKIQY-----ENKEEEQLN
 |..|.||.|.| |.|..|.|..              | |..  .       .. |.|.|.||..      | ...||.   .        .... ..  
GDPDRLRQVLWNLLDNAIKHTPEGHADPDLHDGKPGGGRITVRVH-------RITVEDNGPGIPPEMHKSIEDIPRIFEPFYRTDDSPSRMCPDSRSRKY

NQG-CGLGLLISNSLAKGLVTDKTRNGGISVESEYGIGSKFSILVEDLN
 .|  |||| |...... .  .      |.||      ..|.. .    
GGGLTGLGLSICKRIVEQHGGT------IWVE------TTFTFTLPLER
REC 6574.AA REC 1320-1444 19 2.3e-23 84.89 SMART 1-150 (150) Show / Hide 
Range on Protein: 1320-1444
Range on HMM: 1-150/150
Sequence Identity: 19% (32 aa)

PQIMLVDDN----QFNLYALQ------KIIQQFQFD--------LITFSDGD-------QAIEYIKSQF-FSECCC-----SPQMILMDIEMP-------
. |..|||.    . .. .|.      .. ..  ..         ... ||.       .|.|.....  . |         |. |.|||.||       
MRILIVDDDPAMAPVIREMLRNYTVIQRLLEKEGYENKMWMVEVVDEA-DGETLMNEIWEALELLQEHRDKKEDATTDQSEPPDLIIMDIMMPGDPFEDG

IKNGYETVKEIIQFYKSLQYSNIPVIVACTAYVGQEDFQKSIESGMSDFINKPILKAAFQNLI
  .|.|....|              |...||. . || .. .|.|. |.| ||.    ..  |
GMDGIELCRRIR------------PIIMLTAHDDEEDRVRALEAGADDYITKPFDPEELLARI
Response_reg 6574.AA Response_reg 1322-1445 25 6.8e-19 70.24 Pfam 1-115 (115) Show / Hide 
Range on Protein: 1322-1445
Range on HMM: 1-115/115
Sequence Identity: 25% (32 aa)

IMLVDDNQFNLYALQKIIQ-QFQF-DLITFSDGDQAIEYIKSQFFSECCCSPQMILMDIEMPIKNGYETVKEI-IQFYKSLQYSNIPVIVACTAYVGQED
...|||.. .. .|..|.. . .. .  ...|| .|.|... .        | .|.|||.||  .|.|. ..|  | . . |    . |..|||.   .|
VLIVDDHPLMREGLRQILEQKEGYEVVAEADDGEEALEWWQEHH-------PDLIIMDINMPGMDGLELCRRIRRQHP-HPQ----TPIIMCTAHGDEDD

FQKSIESGMSDFINKPILKAAFQNLIL
 .. .. |. |.| ||. ...  . | 
AVEALQAGANDYITKPFDPDELHAAIR