Gene 6859 (Tetrahymena)

6859

Species: Tetrahymena
Alias: 1044, TTHERM_00495940, 6859, 3715.m00005, 62.m00143, PreTt06859
External Links: Tetrahymena Genome Database (TGD)
Annotation:

Classification

Group: Atypical
Family: HisK

Sequence

Name Sequence Type Origin Length Description Download
6859.AA Protein None 1882 None Fasta, JSON
6859.kin_dom Protein Kinase Domain None 76 None Fasta, JSON
6859.NA RNA None 5649 None Fasta, JSON

Protein domain

Protein domains of 6859.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
HisKA 6859.AA HisKA 901-966 19 0.000651 11.63 SMART 1-89 (89) Show / Hide 
Range on Protein: 901-966
Range on HMM: 1-89/89
Sequence Identity: 19% (17 aa)

LFIDSFQSVSHEFGTALNCINNLSEVALG-----------QMNQESG------------EQLIKPIRYNSAVIQYLINDILDHHMILQN
   . . ..|||. | |. |  ..|...             .. |              ..... |.  .  .| ||||.||   | ..
AKRQFLANMSHELRTPLTAIRGYAELLQDWYYKQRYHHWTDLDPEQRLPMLRREFNCEYREYLETIQREADRMQRLINDLLDLSRIEAG
Kinase 6859.AA HisK 1013-1158 26 9.6e-20 67.84 In-house 1-164 (164) Show / Hide 
Range on Protein: 1013-1158
Range on HMM: 1-164/164
Sequence Identity: 26% (47 aa)

QDKHRIQSILMTMIRNAIKYTQHG------KITVELKIQAVYSNNPTTPKTEKSHNLYESNYVQKIF------------LLGIKVKDTGVGLDESESKKL
.|. ||. ||. .| ||.|.||.|      .|.......  ..|        |  |   |...|||             |. | |.|||.| .|.. ||.
SDPNRIKQILINLISNALKFTQKGGIPFQGYIKIKVEQINTQNN--I-----KY-N---SIFIQKIQENMVQEQLQQKNLIQISVQDTGCGMPEEQQKKI

IHLLNYG----------FCNESISKNSLGNGVGGLCVSNLIAIKLSGR----ENLGIQFERNNESASGTIFRFFVECQ
  .....          | ..... |. | |  || ..| .| .|. .     | |||..   |   |..| |.....
FKMFGNIDDQHQMIKKTFNHQNKKNNQHGCGL-GLTICNNLAKGLGPEHNQNGNRGIQVQ--SEVGKGSTFSFYIYNN
Kinase 6859.AA HATPase_c 1013-1159 18 3.5e-08 34.43 SMART 1-130 (130) Show / Hide 
Range on Protein: 1013-1159
Range on HMM: 1-130/130
Sequence Identity: 18% (32 aa)

QDKHRIQSILMTMIRNAIKYTQH--------------GKITVELKIQAVYSNNPTTPKTEKSHNLYESNYVQKIFLLGIKVKDTGVGLDE----SESKKL
 |  |.. .|   . ||||.|..              |.|||...                                 | |.|.|.|...    |. ...
GDPDRLRQVLWNLLDNAIKHTPEGHADPDLHDGKPGGGRITVRVH--------------------------------RITVEDNGPGIPPEMHKSI-EDI

IHLLNYGF---------CNESISKNSLG--NGVGGLCVSNLIAIKLSGRENLGIQFERNNESASGTIFRFFVECQA
 ...  ..         |. | | .. |   |. || ... |. .. |.    |..|        | |.| .  ..
PRIFEPFYRTDDSPSRMCPDSRSRKYGGGLTGL-GLSICKRIVEQHGGT----IWVE--------TTFTFTLPLER
Kinase 6859.AA HATPase_c 1013-1158 16 6e-06 22.83 Pfam 1-120 (120) Show / Hide 
Range on Protein: 1013-1158
Range on HMM: 1-120/120
Sequence Identity: 16% (28 aa)

QDKHRIQSILMTMIRNAIKYTQH-GKITVELKIQAVYSNNPTTPKTEKSHNLYESNYVQKIFLLGIKVKDTGVGLDE---------------------SE
 |  |.. ..   . ||||.|.  |.|||... .                             . | |.|.|.|...                     . 
GDPDRLHQVVWNLVDNAIKHTPEGGHITVRVHRDD--------------------------DHVRITVEDNGPGIPPEMHSIAEDIPRIFEPFYRTDPD-

SKKLIHLLNYGFCNESISKNSLG--NGVGGLCVSNLIAIKLSGRENLGIQFERNNESASGTIFRFFVECQ
               |   .. |  .|.| | ... |. .. |.       ....|   || |.| .  .
---------------SR-RKYGGGLTGLG-LYICRRIVEQHGGT------IWVESEPGGGTTFTFTLPLE
REC 6859.AA REC 1751-1876 19 1.1e-22 82.64 SMART 1-150 (150) Show / Hide 
Range on Protein: 1751-1876
Range on HMM: 1-150/150
Sequence Identity: 19% (32 aa)

VKVLCVDDE----PFNHFVMK------QILKAKQIN--------CDTALNGE-------EGVEKFKQKK-----KCLSCGQNSYSLILMDLNMP------
 ..|.|||.    | .  ...      ..|.   .         .|.| .||       |..|......        .   . . ||.||..||      
MRILIVDDDPAMAPVIREMLRNYTVIQRLLEKEGYENKMWMVEVVDEA-DGETLMNEIWEALELLQEHRDKKEDATTD-QSEPPDLIIMDIMMPGDPFED

-IKNGFEATYEIKQYSKQHQMSKVIVITCSAFIDIASKIKAQQSGSDFFISKPISQSVLFNLL
   .|.|.. .|.         ..|..|  |. | . ...| ..| | .|.||...  |   .
GGMDGIELCRRIR---------PIIMLT--AHDDEEDRVRALEAGADDYITKPFDPEELLARI
Response_reg 6859.AA Response_reg 1753-1877 28 3.9e-20 74.69 Pfam 1-115 (115) Show / Hide 
Range on Protein: 1753-1877
Range on HMM: 1-115/115
Sequence Identity: 28% (37 aa)

VLCVDDEPFNHFVMKQILK-AKQI-NCDTALNGEEGVEKFKQKKKCLSCGQNSYSLILMDLNMPIKNGFEATYEI-KQYSKQHQMSKVIVITCSAFIDIA
||.|||.| .  ...|||.   .. ....| .|||..|......         . ||.||.|||  .|.|.. .| .| . ..|   . .| |.|. |..
VLIVDDHPLMREGLRQILEQKEGYEVVAEADDGEEALEWWQEHH---------PDLIIMDINMPGMDGLELCRRIRRQHP-HPQ---TPIIMCTAHGDED

SKIKAQQSGSDFFISKPISQSVLFNLLQ
 ...| | | . .|.||...  | . ..
DAVEALQAGANDYITKPFDPDELHAAIR