Gene 7183 (Tetrahymena)

7183

Species: Tetrahymena
Alias: 672, TTHERM_00420580, 7183, PreTt07183, 46.m00238, 3679.m00088
External Links: Tetrahymena Genome Database (TGD)
Annotation:

Classification

Group: Atypical
Family: HisK

Sequence

Name Sequence Type Origin Length Description Download
7183.AA Protein None 1070 None Fasta, JSON
7183.kin_dom Protein Kinase Domain None 112 None Fasta, JSON
7183.NA RNA None 3213 None Fasta, JSON

Protein domain

Protein domains of 7183.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
HisKA 7183.AA HisKA 385-450 23 4.8e-10 37.98 Pfam 1-69 (69) Show / Hide 
Range on Protein: 385-450
Range on HMM: 1-69/69
Sequence Identity: 23% (16 aa)

YKDDLINTVTHDLKTPLNGIISILESAISLTSFNEMQ---KCIQIARKNGVLLTAIINDIQDFQNMKKG
 | ... .. |.|.|||..|.  .| .   |  .. |   . ...... .  . ..|||. ||  .  |
AKRQFLANMSHELRTPLTAIRGYAELLQDYTDLDPEQMRREYLETIQREAQRMQRLINDLLDFSRIEAG
HisKA 7183.AA HisKA 385-450 16 6.6e-10 40.15 SMART 1-89 (89) Show / Hide 
Range on Protein: 385-450
Range on HMM: 1-89/89
Sequence Identity: 16% (15 aa)

YKDDLINTVTHDLKTPLNGIISILESAIS---------LTSFNEMQ--------------KCIQIARKNGVLLTAIINDIQDFQNMKKG
 |.... .. |.|.|||..|.  .| .            |  .. |              . ...... .  . ..|||. |.  .  |
AKRQFLANMSHELRTPLTAIRGYAELLQDWYYKQRYHHWTDLDPEQRLPMLRREFNCEYREYLETIQREADRMQRLINDLLDLSRIEAG
Kinase 7183.AA HisK 496-607 31 1.1e-52 181.38 In-house 1-164 (164) Show / Hide 
Range on Protein: 496-607
Range on HMM: 1-164/164
Sequence Identity: 31% (52 aa)

NDFNRIKQIVLNLIGNALKFTFKG------YVFFEITQLN--------------------------NQYLKFAIADTGIGISTQLQKKIFQPYG------
.| ||||||..|||.||||||.||      |. ....| |                          ...... . |||.|.. ..|||||...|      
SDPNRIKQILINLISNALKFTQKGGIPFQGYIKIKVEQINTQNNIKYNSIFIQKIQENMVQEQLQQKNLIQISVQDTGCGMPEEQQKKIFKMFGNIDDQH

-----TYQQKKN--YQHGCGIGLAICQKLVQKVG-------NGNIELISKEGQGSTFIFLVHRF
     |.....   .|||||.||.||..|....|       |..|...|..|.||||.|..  .
QMIKKTFNHQNKKNNQHGCGLGLTICNNLAKGLGPEHNQNGNRGIQVQSEVGKGSTFSFYIYNN
Kinase 7183.AA HATPase_c 496-607 27 1e-27 98.66 Pfam 1-120 (120) Show / Hide 
Range on Protein: 496-607
Range on HMM: 1-120/120
Sequence Identity: 27% (34 aa)

NDFNRIKQIVLNLIGNALKFTFK-GYVFFEITQLNNQYLKFAIADTGIGIST------QLQKKIFQPYGTYQQ--KKNYQHG--CGIGLAICQKLVQKVG
.| .|..|.|.||..||.|.| . | .  .... .  .. . . |.|.||.       ... .||.|.... .        |   |.||.||...|...|
GDPDRLHQVVWNLVDNAIKHTPEGGHITVRVHRDD-DHVRITVEDNGPGIPPEMHSIAEDIPRIFEPFYRTDPDSR-RKYGGGLTGLGLYICRRIVEQHG

NGNIELISKEGQGSTFIFLVHRF
 | |.. |..|.|.||.| . . 
-GTIWVESEPGGGTTFTFTLPLE
Kinase 7183.AA HATPase_c 496-608 20 5.3e-24 86.97 SMART 1-130 (130) Show / Hide 
Range on Protein: 496-608
Range on HMM: 1-130/130
Sequence Identity: 20% (29 aa)

NDFNRIKQIVLNLIGNALKFTFK--------------GYVFFEITQLNNQYLKFAIADTGIGIST------QLQKKIFQPYGTYQQ---------KKNYQ
.| .|..|...||..||.|.| .              | .  ..         . ..|.|.||.       .....||.|...  .         .    
GDPDRLRQVLWNLLDNAIKHTPEGHADPDLHDGKPGGGRITVRVH-------RITVEDNGPGIPPEMHKSIEDIPRIFEPFYRTDDSPSRMCPDSRSRKY

HG--CGIGLAICQKLVQKVGNGNIELISKEGQGSTFIFLVHRFL
 |   |.||.||...|.. |   |..       .||.| . . .
GGGLTGLGLSICKRIVEQHGGT-IWVE------TTFTFTLPLER
REC 7183.AA REC 943-1062 26 1.9e-23 85.13 SMART 1-150 (150) Show / Hide 
Range on Protein: 943-1062
Range on HMM: 1-150/150
Sequence Identity: 26% (43 aa)

K-----DDT----GFNILALK------LLLKQQIST-----QTEVFEAFNGR-------QALEIVKEKFRSQQY--------VNLILMDVNMP-------
.     ||       .  .|.      .||...  .       .| || .|.       .|||...|. ...          . ||.||..||       
MRILIVDDDPAMAPVIREMLRNYTVIQRLLEKEGYENKMWMVEVVDEA-DGETLMNEIWEALELLQEHRDKKEDATTDQSEPPDLIIMDIMMPGDPFEDG

IMDGIEATRIIKNLVKEGKMNPLKIVMITAFGSLKDRENAKLAGADAYMEKPVTVNSLIAAI
 |||||..| |.           .|.|.||...  ||. |  ||||.|. ||.. . |.|.|
GMDGIELCRRIR-----------PIIMLTAHDDEEDRVRALEAGADDYITKPFDPEELLARI
Response_reg 7183.AA Response_reg 952-1063 35 7.5e-19 70.09 Pfam 13-115 (115) Show / Hide 
Range on Protein: 952-1063
Range on HMM: 13-115/115
Sequence Identity: 35% (41 aa)

ALKLLLKQQISTQTEVFEAFNGRQALEIVKEKFRSQQYVNLILMDVNMPIMDGIEATRII-KNLV-KEGKMNPLKIVMITAFGSLKDRENAKLAGADAYM
.|. .|.|. .  ..| || .|..|||...|.      . ||.||.||| |||.|..| | ...   .     ..|.|.||.|.. |.. |  |||. | 
GLRQILEQK-EGYEVVAEADDGEEALEWWQEHH-----PDLIIMDINMPGMDGLELCRRIRRQHPHPQ-----TPIIMCTAHGDEDDAVEALQAGANDYI

EKPVTVNSLIAAIE
 ||.  . |.|||.
TKPFDPDELHAAIR