Gene 27105 (Tetrahymena)

27105

Species: Tetrahymena
Alias: 8.m00365, 27105, 3812.m02402, TTHERM_00112910, 1096, PreTt27105
External Links: Tetrahymena Genome Database (TGD)
Annotation:

Classification

Group: Atypical
Family: RIO
Subfamily: RIO2

Sequence

Name Sequence Type Origin Length Description Download
27105.AA Protein None 548 None Fasta, JSON
27105.kin_dom Protein Kinase Domain None 183 None Fasta, JSON
27105.NA RNA None 1647 None Fasta, JSON

Protein domain

Protein domains of 27105.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Kinase 27105.AA RIO2 71-288 55 1.7e-162 546.14 In-house 1-260 (260) Show / Hide 
Range on Protein: 71-288
Range on HMM: 1-260/260
Sequence Identity: 55% (145 aa)

YKLTYLGYDYLALQVFIRRGAIKEVLGKVGCGKESDIYKCVNENGDFVILKFTRLGRTSFRTIKKNRDYIQHRTSYSWLYLSRLSAIKEYTFMDLLHKNN
|.||  |||||||.    |  .  |  ..| |||||||||.||||...|.||.|||||||..||.||||..||..|||.|||||||.|||.|||.|.|.|
YRLTNAGYDYLALKTLSSRQVVYSVGNQMGVGKESDIYKCSNENGNQFIMKFHRLGRTSFHNIKNNRDYHKHRHQYSWMYLSRLSAMKEYQFMDMLYKRN

FPTPIPIEQNRHGIVMSLINGVPMQNISEIDNPKYVFDQCFYLIKRLAENGLIHSDFNEFNLMVEDNGK------VIMIDFPQMVSTKHKNAQFYFDRDV
||.|.||..|||..||.||||.||..|...|||.||.|||...|.|||..||||.||||||||..||..      .|||||||||||.|.|||.||||||
FPVPKPIDYNRHIVVMELINGYPMCQIHHHDNPPYVYDQCMCFIVRLANHGLIHCDFNEFNLMIDDNDHDENDCGFIMIDFPQMVSTQHQNAQWYFDRDV

ECIHVFFERRFNY-----------------------------QITDTLD-------FNKI
.|||.||..||||                             |.|||||       |||.
DCIHRFFMKRFNYEPKPFPSMLDTEGFGDGYKYAYPDFFRDIQRTDTLDEEVQASGFNKK
Kinase 27105.AA RIO 71-288 35 1.1e-129 437.2 In-house 1-276 (276) Show / Hide 
Range on Protein: 71-288
Range on HMM: 1-276/276
Sequence Identity: 35% (99 aa)

YKLTYLGYDYLALQVFIRRGAIKEVLGKVGCGKESDIYKCVNENGD-----------FVILKFTRLGRTSFRTIKKNRD---YIQHRTS-YSWLYLSRLS
|..|  .|.....   . || . .| . .| |||||||.|.||||.           ....|..|.|||||...||.||   |..||.. ..|.|..||.
YEQTNDPYTRMIMYKMVNRGMVESVGNCIGVGKESDIYHCSNENGEDEKEDSKVIPTECAIKIHRTGRTSFKDRKKYRDGEFYFKHRHCKHNWRYMHRLW

AIKEYTFMDLLHKNNFPTPIPIEQNRHGIVMSLING-------VPMQNISEIDNPKYVFDQCFYLIKRLAENG-LIHSDFNEFNLMVEDNGK------VI
|.||...|..|....||.|.||...||..||..||.       .||..|.|..|.|.|..||.....||.... |.|.||||||.|..|...      ..
AEKEMRNMKRLYQSGFPCPEPIDYKRHVLVMEFINHDQMPAPKYPMCQIHEHENMKHVYHQCMCYMRRLYQHCRLVHCDFNEFNMMWHDGKHDENDCGFY

MIDFPQMVSTKHKNAQFYFDRDVECIHVFFERRFNYQ-----------------------------ITDTLDFNKI
||||||||...|..|..||.||..|...||..||.|.                             .|||||....
MIDFPQMVEHDHPHALWYFRRDCKCVNMFFMKRFVYEPFPEREMFDFVGFGDGYKYAYPDFKRDVKRTDTLDHENM
Kinase 27105.AA RIO1 106-288 28 3.2e-60 188.27 Pfam 1-200 (200) Show / Hide 
Range on Protein: 106-288
Range on HMM: 1-200/200
Sequence Identity: 28% (58 aa)

DIYKCVN-ENGD-FVILKFTRLGRTSFRTIKKNRDYIQH----RTSYSWLYLSRLSAIKEYTFMDLLHKNNFPTPIPIEQNRHGIVMSLIN---GVPMQN
..|...  |.|. ....|. |.|.|.|. .|. ||| ..    .  ..|.|..|..| ||. ..  ...  .| | ||. ||| .||..|    |.|. .
NVYHAYSMEDGKDECAVKIYRTGTTCFKKMKRYRDYDFRFRHRYHHHNWRYMVRMWAEKEFRNLKRMYEAGVPCPKPIDWNRHVLVMEFIGDKDGWPAPR

ISEID--------NPKYVFDQCFY--LIKRLAENGLIHSDFNEFNLMVEDNGKVIMIDFPQMVSTKHKNAQFYFDRDVECIHVFFERRFNYQITDTLDFN
. . .        ... ..|..    ......| ||.| |..|.|..| |.||. .||.||.|.. | .| ....||...|. ||.|.. .    ..||.
LKDVEMELELSEEEAEEIYDEIIREYMRRMYQECGLVHGDLSEYNILVHDDGKPWIIDWPQAVEHDHPHALEFLERDCRNIINFFRRKGVDER--VMDFR

KI
.|
EI
RIO 27105.AA RIO 64-290 21 1.3e-48 168.78 SMART 1-253 (253) Show / Hide 
Range on Protein: 64-290
Range on HMM: 1-253/253
Sequence Identity: 21% (54 aa)

ENKKFDGYKLTYLGYDYLALQVFIRRGAIKEVL--GKVGCGKESDIYKCVN----ENGDFVILKFTRLGRTSFRTIKKNRD-YIQHR---TSYSWLYLSR
.......| ... ......|  ...|| |.|.   |... |||...|. ..    .||...  |. |...|.|........ .   .      .|....|
DKEDYATYEEVFDPRTRMTLYKMVNRGYIEEINNHGCISTGKEANVYHAMGGDFDKNGNECAVKIYRTSTTEFKRMWRYIQGDFRFKHGYHHINWRKMVR

LSAIKEYTFMDLLHKNNFPTPIPIEQNRHGIVMSLING--VPMQNISEIDNPK-------YVFDQCFYLIKRLAENG-LIHSDFNEFNLMVE-----DNG
|.| ||....  ...  .| | ||. .|| .||..| .  .|.   .....          ...|    ........ |.| |..|.|...      ...
LWAEKEFRNLQRMYEAGVPCPKPIAWRRHVLVMEFIGDDGWPAPRLKDVEWEEWEMDFKWEYYWQIMEYMRKMYHECHLVHADLSEYNMLYHDLEDENDC

KVIMIDFPQMVSTKHKNAQFYFDRDVECIHVFFERRFNYQIT-DTLDFNKIAR
|| .||..| |.. |  . ... ||...|  ||.|.  .       .|..|  
KVWIIDWSQSVECDHPMWLEFLERDIWNIINFFRRKGVDCDDIYREIFERITG
Rio2_N 27105.AA Rio2_N 8-89 53 1.8e-44 152.43 Pfam 1-84 (84) Show / Hide 
Range on Protein: 8-89
Range on HMM: 1-84/84
Sequence Identity: 53% (45 aa)

LEYMTKDEFRVLTAIEIGMRNHELVPMHLIERISHLK-RVCASKVVKLLLKNKFIAH-ENKKFDGYKLTYLGYDYLALQVFIRR
. |..|..||||||.|.||||||.|| .||..||.|. ..  ..... |.|.|.|.| .|||.|||.|||.|||||||  | .|
MRYLSKEDFRVLTAVEMGMRNHEWVPTELIHQISRLRSHGGCHYRLSRLCKHKLISHVQNKKYDGYRLTYGGYDYLALHTFVKR
Kinase 27105.AA RIO3 153-273 28 3e-06 16.25 In-house 101-227 (254) Show / Hide 
Range on Protein: 153-273
Range on HMM: 101-227/254
Sequence Identity: 28% (37 aa)

RLSAIKEYTFMDLLHKNNFPTPIPIEQNRHGIVMSLI--NGVPMQNISEI----DNPKYVFDQCFYLIKRL-AENGLIHSDFNEFNLMVEDNGKVIMIDF
|. | ||   .  . .   | |  .   .| .|||.|  . ||   . |.    .. |  . | ..|...|  |  |.|.|. |.| |.   ||| .|| 
RMWAEKEMHNLARMQRAGIPCPTVVLLKKHILVMSFIGHDQVPAPKLKEVKLNSEEMKEAYYQTLHLMRQLYHECTLVHADLSEYN-MLWHAGKVWLIDV

PQMVSTKHKNAQFYFDRDVECIHVFFER
 | |   |     .. ||.  .  ||..
SQSVEPTHPHGLEFLFRDCRNVSQFFQK
Kinase 27105.AA RIO2 294-306 69 0.000532 9.46 In-house 248-260 (260) Show / Hide 
Range on Protein: 294-306
Range on HMM: 248-260/260
Sequence Identity: 69% (9 aa)

LDVQVKASGFIKK
||. | |||| ||
LDEEVQASGFNKK