20428

Species: Tetrahymena
Alias: 141.m00085, 651, PreTt20428, 3682.m00019, TTHERM_00823550, 20428
External Links: Tetrahymena Genome Database (TGD)
Annotation:

Classification

Group: CAMK
Family: CAMKL
Subfamily: AMPK

Sequence

Name Sequence Type Origin Length Description Download
20428.AA Protein None 692 None Fasta, JSON
20428.kin_dom Protein Kinase Domain None 294 None Fasta, JSON
20428.NA RNA None 2079 None Fasta, JSON

Protein domain

Protein domains of 20428.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Kinase 20428.AA AMPK 15-308 49 4e-190 569.55 In-house 1-254 (254) Show / Hide
Range on Protein: 15-308
Range on HMM: 1-254/254
Sequence Identity: 49% (150 aa)

YLVGKTLGCGASGKVKREQFRLFKLTFFRGVQFTLLINQSSLSSENAKIFSKKSEFKNIFCFIIVAKHDITGKEVAIKIINKKKMTVKKMSNKIKREIRL
|..|||.|.|..||||                                                ...|..||..|||||.||.|.. ..|...|.|||..
YIIGKTIGEGTFGKVK------------------------------------------------MGTHILTGEKVAIKILNKQKIKDQDMVERIQREIHI

LRFFNHQNIIRLYEVL-DTNTDIFVVTEYISGGDLYDVIASKGKLPEQEAKRYFKQIVAGVDYCHRNLVAHRDLKLENILIDDNNNIKIADFGLSNIMND
|..|.|..||.||||. .|.||||.|.||.|||.|.|.|...|.|.|.||.|.|.||..||.||||. ..|||||.||.|.|.|.||||.||||||.|.|
LKLFRHPHIIQLYEVIIETPTDIFMVMEYVSGGELFDYIVKHGRLQEREACRFFQQIISGVEYCHRHMIVHRDLKPENLLLDHNKNIKIVDFGLSNMMKD

GKYLSTSCGSPNYAAPEVISGKLYCGTEVDTWSCGVILFALLGGYLPFDEEVIPALYKKIK-------AFFSPEAHDIIKRMLRPNPIERIKFHELRLHP
|..|.|.||||.|||||.||||||||.|||.|||||||.|.|.||||||.|..|.||||||       .|.||||.|.||.||...|..||..|..| ||
GEFLKTACGSPCYAAPEMISGKLYCGPEVDIWSCGVILYAMLCGYLPFDDENTPTLYKKIKNGEYYIPKFLSPEAKDLIKHMLQVDPMKRITIHDIRNHP

WL
|.
WF

Kinase 20428.AA CAMKL 15-308 37 1.2e-138 445.13 In-house 1-297 (297) Show / Hide
Range on Protein: 15-308
Range on HMM: 1-297/297
Sequence Identity: 37% (130 aa)

YLVGKTLGCGASGKVKREQFRLFKLTFFRGVQFTLLINQSSLSSENAKIFSKKSEFKNIFCFIIVAKH-DITGKEVAIKIINKKKMTV------------
| .|||||.|. ||||                                                 |.|  .||..||||||.|||..             
YRIGKTLGKGSFGKVK------------------------------------------------LATHIRTTGEKVAIKIIDKKKIWNDPWMKKNKCGQK

-KKMSNKIKREIRLLRFFN---HQNIIRLYEVL-------DTNTDIFVVTEYISGGD--LYDVIASK----GKLPEQEAKRYFKQIVAGVDYCHRNLVAH
 ...  .|.|||.... .|   |.|||.||||.       .| ..|. |.||.|||.  |.| | ..    |..|| ||.|||.|||..|.|||.. ..|
HESDM-RIRREIQIMKMLNIGKHPNIIKLYEVIETPEHDIET-KKIYLVMEYCSGGEMDLFDYIVKHGHRRGRMPEHEARRYFRQIVSAVNYCHSHGIVH

RDLKLENILIDDNN--NIKIADFGLSNIMND-----GKYLSTSCGSPNYAAPEVISG--KLYCGTEVDTWSCGVILFALLGGYLPFDEE--------VIP
||.|.||||.|.|.  ||||.|||.||.. .     |. |.|.||||.|.|||...|  | |.| .|| |||||||.|.. ||||||..         | 
RDIKPENILLDENGNNNIKIIDFGFSNMYRPCIFGPGQKLKTFCGSPPYMAPEIFQGNNKPYDGPKVDIWSCGVILYAMVCGYLPFDDDTYNKQGKDNI-

ALYKKIKA-FFSP------EAHDIIKRMLRPNPIERIKFHELRLHPWL
 ||.||.  .. |      ...|.|..|| .|| .|.. |... |||.
YLYWKIMCGYYPPIWYHVSDCRDLIRKMLQVNPEKRPTIHQIMNHPWM

Kinase 20428.AA CAMK 20-308 24 1.2e-116 377.5 In-house 1-425 (425) Show / Hide
Range on Protein: 20-308
Range on HMM: 1-425/425
Sequence Identity: 24% (117 aa)

TLGCGASGKVKREQFRLFKLTFFRGVQFTLLINQSSLSSENAKIFSKKSEFKNIFCFIIVAKHDITG------------KEVAIKIINKKKMTV------
||| |. ||||                                                 ..|  |.            ..||||||.|||..       
TLGRGSFGKVK------------------------------------------------LCIHKNTTGKERVHHIYTNGQKVAIKIIDKKKLKDKQNQDY

-------------------KKMSNKIKREIRLLRF-------FNHQNIIRLYEVLD------------TNTD--------IFVVT---EYISGG----DL
                    |.  ...|||....         .| |||.|||| .            | ..        .. |.   ||.|||    ||
SNCYKIDKSKCKHRYCWRRPKDRKNVRREIEIMKKLQGIGNKLDHPNIIKLYEVYEDPHYFKNTNDYET-SKQVFTKDKHMYMVMEIMEYCSGGELFDDL

YDVIASK---------------GKLPEQEAKRYFKQIVAGVDYCHRNLVAHRDLKLENILIDDN-----------------NNIKIADFGLSNIMND---
.| | ..               |...|.||.|||.||. .|.||| . ..|||||.||||.|||                 |||||.|||..|....   
FDYIVEHGCYGEEFDQFDIVERGRFTEREARRYFRQICSAVHYCHSHNIVHRDLKPENILLDDNNDDSDPVEHDEIFDWNNNNIKIIDFGFANKFDPGEN

---------------------GKYLSTSCGSPNYAA-PEVISG-------------KLYCGTEVDTWSCGVILFALLGGYLPFDEE-------------V
                     |. ..|.||.| |.| |||..|             | |.| ..| |||||||...| ||.||...              
NFMCSDYKGGEMHNQWTTPTEGQKMKTFCGTPEYMAAPEVLNGKGHCNMQNATDEEKPYYGPKCDMWSCGVILYIMLCGYPPFYGDCDNEICEDEWIGMN

IPALYKKIK----AFFSPE---------------------------AHDIIKRMLRPNPIERIKFHELRLHPWL
.. |..||.     | .|.                           . | |..||...| .|.. ..   |||.
DYELFEKIMKGKYDFPPPYFSPISCNYGPEWWDDISDEFHHFVSQECKDLIRKMLQVDPEKRMTIEQCLNHPWM

Kinase 20428.AA MARK 79-308 44 1.8e-110 362.26 In-house 17-262 (262) Show / Hide
Range on Protein: 79-308
Range on HMM: 17-262/262
Sequence Identity: 44% (109 aa)

VAKHDITGKEVAIKIINKKKMTV-KKMSNKIKREIRLLRFFNHQNIIRLYEVLD--TNTD-IFVVTEYISGGDLYDVIASK--GKLPEQEAKRYFKQIVA
.| |  ||..|||||..|.|..  ..|.| ..|||....  .| |||.|..| .  |..  |... ||.|||.||| | ..  |.|.| ||.|.|.||| 
LACHKHTGRKVAIKIYEKFKLNDPQWMKN-VMREIEIMKKLDHPNIIKLFHVIEQDTEQHQIYLIMEYASGGELYDYIKAHPNGRLHEEEARRIFRQIVS

GVDYCHRNLVAHRDLKLENILIDDNN--NIKIADFGLSNIMNDGKYLSTSCGSPNYAAPEVISGKLYCGTEVDTWSCGVILFALLGGYLPFDEEV--IPA
.| |||.. ..|||.|.||||||.|.  ||||.|||.|.. . |. |.| ||.| |.|||....| |.|..||.||.||.|.... ||.|||.    .  
AVNYCHSKNIVHRDIKPENILIDENGNHNIKIIDFGFSICIPPGQKLNTFCGTPPYMAPEIFLKKPYDGPKVDIWSLGVVLYFMVCGYFPFDGDTQDYKE

LYKKIKA--FF-----SPEAHDIIKRMLRPNPIERIKFHELRLHPWL
||||| .  .      |.|....|.|.| .|| ||.. .|.  |||.
LYKKILRGKYDIPCHVSKECRNLIQRLLTVNPEERPTIEEIMKHPWM

Kinase 20428.AA NuaK 85-308 46 6.2e-108 284.89 In-house 23-252 (252) Show / Hide
Range on Protein: 85-308
Range on HMM: 23-252/252
Sequence Identity: 46% (108 aa)

TGKEVAIKIINKKKMTVKKMSNKIKREIRLLRFFNHQNIIRLYEVLDTNTDIFVVTEYISGGDLYDVIASKGKLPEQEAKRYFKQIVAGVDYCHRNLVAH
||.||||| | |.|   ..   .| |||...   || .||  |||      | .| || |||.||| | ....|||.||.. | |||  | |||.. ..|
TGREVAIKSIKKCKIEDEQDMVHIRREIEIMSSLNHPHIIHIYEVFENKDKIVIVMEYASGGELYDYISECKSLPEREARHFFRQIVSAVHYCHKHRICH

RDLKLENILIDDNNNIKIADFGLSNIMNDGKYLSTSCGSPNYAAPEVISGKLYCGTEVDTWSCGVILFALLGGYLPFDEEVIPALYKKIK--AFFSPE--
||||||||| |.|.|.|||||||||. .|.| | | |||| || ||.. |. | | ||| || ||.|...  | .||| .    | | |.  |.. |.  
RDLKLENILLDQNCNAKIADFGLSNYYHDQKFLHTFCGSPLYASPEIVNGQPYHGPEVDCWSLGVLLYTMVYGTMPFDGHDFKHLVKQISQGAYYEPCKP

--AHDIIKRMLRPNPIERIKFHELRLHPWL
  |   |  ||. ||  |    .   |.|.
SDACMLIRWMLMVNPRRRATIYDICHHWWV

Kinase 20428.AA S_TKc 15-308 32 2.9e-94 320.38 SMART 1-231 (231) Show / Hide
Range on Protein: 15-308
Range on HMM: 1-231/231
Sequence Identity: 32% (100 aa)

YLVGKTLGCGASGKVKREQFRLFKLTFFRGVQFTLLINQSSLSSENAKIFSKKSEFKNIFCFIIVAKHDITGKEVAIKIINKKKMTVKKMSNKIKREIRL
| .....| || |||.. . .                                                 ||..||||||.          ..|.|||..
YEILRKIGKGAFGKVYKCRHKK------------------------------------------------TGRIVAIKIIK----------EHIRREIQI

LRFFNHQNIIRLYEVLDTNTDIFVVTEYISG--GDLYDVIASKGK------LPEQEAKRYFKQIVAGVDYCHRNLVAHRDLKLENILIDDNNNIKIADFG
|.  .| ||..||.| .. .....|.||..|  |||.|.| ..|.      .|| .|..|..||. ...|||.. . ||||| ||||.|.  .|||.|||
LKK-HHPNIVKLYDVFQD-DHLYMVMEYCDGDLGDLFDYIKKRGRHGLRFPFPE-HARFYMYQICCALEYCHSHGIIHRDLKPENILLDE--HIKICDFG

LSNIMNDGKYLSTSCGSPNYAAPEVISGKLYCGT-EVDTWSCGVILFALLGGYLPFDEEVIPALYKKIKAFFSPEAHDIIKRMLRPNPIERIKFHELRL-
|. ..      .| ||.|.| ||||.      |. ..| ||||.||. .| || ||.   . ...|||.   |||| |.|...|. .| .|.   |.   
LARQL------TTFCGTPWYMAPEVL----GYGKCKCDWWSCGCILYEMLCGYPPFP--QMQMMFKKIG---SPEAKDFIRKCLQKDPEKRPTA-EALQD

------HPWL
      |||.
EWDIKCHPWF

Kinase 20428.AA QIK 80-308 39 6.9e-91 308.26 In-house 18-272 (272) Show / Hide
Range on Protein: 80-308
Range on HMM: 18-272/272
Sequence Identity: 39% (101 aa)

AKHDITGKEVAIKIINKKKMTVKKMSNKIKREIRLLRFFNHQNIIRLYEVLDTNTDIFVVTEYISGGDLYDVIASKGK--------------------LP
|.| || ..|||||| | ... . . .|..||. ..   .| .||.||.|. |   ...|||| |.|...| ....|.                    ..
ARHRITKTKVAIKIIDKSQLDEENL-QKCYREVQIMKMLYHPHIIKLYQVMETDDMMYIVTEYCSNGEMFDYLCKHGRKGVKMVNSPDIGDQVLMGVPMA

EQEAKRYFKQIVAGVDYCHRNLVAHRDLKLENILIDDNNNIKIADFGLSNIMNDGKYLSTSCGSPNYAAPEVISGKLYCGTEVDTWSCGVILFALLGGYL
|.||.| |.||...|.|||.  ..||||| ||||.| | ||||||||.||    |. |.| |||| |||||.  || | | .|| || ||.|..|  | |
ENEARRWFWQICSAVHYCHKRNIVHRDLKAENILLDNNMNIKIADFGFSNWFKQGQLLMTWCGSPPYAAPEMFEGKEYDGPKVDIWSMGVVLYVLVCGAL

PFDEEVIPALYK-------KIKAFFSPEAHDIIKRMLRPNPIERIKFHELRLHPWL
||| . .. | .       .|  | | .  ..|..||  .|  |.     . |.|.
PFDGKTLQNLRQRVLSGKFRIPFFMSQDCEHLIRHMLVVDPEHRYTIMQICQHRWM

Kinase 20428.AA BRSK 82-308 43 2.9e-83 282.93 In-house 20-254 (254) Show / Hide
Range on Protein: 82-308
Range on HMM: 20-254/254
Sequence Identity: 43% (102 aa)

HDITGKEVAIKIINKKKMT-VKKMSNKIKREIRLLRFFNHQNIIRLYEVLDTNTDIFVVTEYISGGDLYDVIASKGKLPEQEAKRYFKQIVAGVDYCHRN
| .||| |||||||| |.     |  |. ||| ...  .| .....|.|  .    . . |..||| |.|    ||.|  .||...|.||. ..|.||  
HCVTGKKVAIKIINKEKLSNKESMLMKVEREIAIMKLIDHPHVMKMYDVYENKKYLYLILEHVSGGELFDYLVKKGRLTPKEARKFFRQIISALDFCHSH

LVAHRDLKLENILIDDNNNIKIADFGLSNIMNDGKYLSTSCGSPNYAAPEVISGKLYCGTEVDTWSCGVILFALLGGYLPFDEEVIPALYKKIK------
 . ||||| || | |. |||||||||.  .  ..  | |||||| || ||||.|  | |   | |||||||.||| | |||| . .  |  |.|      
NICHRDLKPENLLLDEKNNIKIADFGMASLQVKDMMLHTSCGSPHYACPEVIRGEKYDGRKADVWSCGVILYALLVGALPFDDDNLRQLLEKVKRGVFHM

-AFFSPEAHDIIKRMLRPNPIERIKFHELRLHPWL
  |  | . |  . |.  .|  ||  .| . ||| 
PHFIHPDCQDLLRGMIEVDPDKRISLKEIQKHPWY

Kinase 20428.AA Pkinase 80-308 34 1.9e-82 284.99 Pfam 18-293 (293) Show / Hide
Range on Protein: 80-308
Range on HMM: 18-293/293
Sequence Identity: 34% (96 aa)

AKHDITGKEVAIKIINKKKMTVKKMSNKIK-REIRLLRFFNHQNIIRLYEVLDTNTDIFVVTEYISGG----DLYDVIA--SKGKL--PEQEAKRYFKQI
..|  |||.||.|||.|..   .|  .... .||.... .|| ||.|||..  ....| .|.||  ||    ||.|.|   ..|..  .|.|.|.|..||
CHHKGTGKIVAVKIIKKRHEKSWKDQTHRRLSEIQIMKRLNHPNIVRLYDWFEDKDHIYMVMEYCEGGLYVMDLFDYISTWRHGCFYFSEWECKFYMYQI

VAGVDYCHRNLVAHRDLKLENILIDDNNNI----KIADFGLSNI--MNDGKYLSTSCGSPNYAAPEVISGKLYCGTEVDTWSCGVILFALLGGYLPFDEE
. |..|||.. . |||||.||||||.|..|    ||.||||.       .  ..| ||.|.|.||||| |  | |..|| ||||.||. .| |..||...
LRGLEYCHSMGIIHRDLKPENILIDNNGHIDACVKICDFGLAKQFDY-NNS-MTTFCGTPWYMAPEVIRGGQYYGPKVDMWSCGCILYEMLCGRPPFPGH

------VIPALYKKIKA-------FFS---------------------PEAHDIIKRMLRPNPIERIKFHELRLHPWL
         .....|.        . .                     .|. |.||..|...| .|. ....  |||.
CWHDNHDQMQMICRIMGPPLHFDWPWWCSISYFFFRHWHFHWTFHNWSEECKDFIKWCLCKDPKKRPTAEQILQHPWF

Kinase 20428.AA GIN4 108-308 47 6.3e-81 258.16 In-house 81-293 (293) Show / Hide
Range on Protein: 108-308
Range on HMM: 81-293/293
Sequence Identity: 47% (101 aa)

IKREIRLLRFFNHQNIIRLYEVLDTNTDIFVVTEYISGGDLYDVIASKGKLPEQEAKRYFKQIVAGVDYCHRNLVAHRDLKLENILIDDNNN-IKIADFG
| ||| ...  .| |..|||.| .||.|...| ||. .|.|.... ..|.|||.|| .||.||. || |||   . ||||| ||.|.|  .| |||||||
IEREIVIMKLISHPNVMRLYDVWETNNDLYLVLEYAEKGELFNYLVDHGPLPEREAIHYFRQIIIGVSYCHAFNICHRDLKPENLLLDHKYNRIKIADFG

LSNIMNDGKYLSTSCGSPNYAAPEVISGKLYCGTEVDTWSCGVILFALLGGYLPFDEE--VIPALYKKIK---------AFFSPEAHDIIKRMLRPNPIE
.  .  |.| | |||||| |||||...|  | |   | ||||||||||| | ||||||   |  |  |..            | ||.|.|...|   |  
MAALETDNKLLETSCGSPHYAAPEIVMGIPYHGFASDVWSCGVILFALLTGHLPFDEEDGNIRKLLLKVQKGKYEMPSDDEISREAQDLIRKILVVDPEK

RIKFHELRLHPWL
||| ...  || .
RIKTRDILKHPLI

Kinase 20428.AA MELK 74-308 39 2.1e-72 246.7 In-house 12-254 (254) Show / Hide
Range on Protein: 74-308
Range on HMM: 12-254/254
Sequence Identity: 39% (96 aa)

FCFIIVAKHDITGKEVAIKIINKKKMTVKKMSNKIKREIRLLRFFNHQNIIRLYEVLDTNTDIFVVTEYISGGDLYDVIASKGKLPEQEAKRYFKQIVAG
|  . .| | .|.. |||||..|...       ..| |.  |. . ||.| .|| ...|.  ||.| || .||...| | .. .| |.|.. .|.|||. 
FAKVKLACHILTNQMVAIKIMDKNQLGHDLP--RVKTEMDALKNLRHQHICQLYHYIETEDKIFMVMEYCPGGEMFDYIIRQDRLEEEETRHFFRQIVSA

VDYCHRNLVAHRDLKLENILIDDNNNIKIADFGLSNIM--NDGKY-LSTSCGSPNYAAPEVISGKLYCGTEVDTWSCGVILFALLGGYLPFDEEVIPALY
. | |    |||||| ||.|.|.. ..|. ||||      .  .. | | |||| |||||.|.|| | | | | || |..|..|. |.||||.. . ..|
IAYVHSQGYAHRDLKPENLLFDEDHHLKLIDFGLCAKTKGRKDYHNLQTCCGSPAYAAPELIQGKQYIGSEADVWSMGILLYVLMCGFLPFDDDNMMIMY

KKIKA-------FFSPEAHDIIKRMLRPNPIERIKFHELRLHPWL
|||         . |||. .....||  .|  ||. ..|  |||.
KKIMSGCYEEPKWLSPESKQLLRHMLQVDPKKRISMKNLLNHPWV

Kinase 20428.AA Ciliate-E2 15-308 23 2.6e-71 243.21 In-house 1-365 (365) Show / Hide
Range on Protein: 15-308
Range on HMM: 1-365/365
Sequence Identity: 23% (99 aa)

YLVGKTLGCGASG-----KVKRE------------------QFRLFKLTFFRGVQFTLLINQSSLSSENAKIFSKKSEFKNIFCFIIVAKHDITGKEVAI
| . | .| |. |     ||...                  |                                                   ..|..|.
YKFIKKIGQGNFGSVYKCKVWKVQKQFAIKIIDQKQQRQQMQ------------------------------------------------EKVKIKIYAM

KIINKKKMTVKKMSNKIKREIR----------LLRFFNHQNIIRLYEVLD--TNTDIFVVTEYISGGDLYDVIASK-----------GKLPEQEAKRYFK
||..|..   .|. ..| |||.          .|.. || |||..||.    ... |. |.||..||||.| | ..           ... |.|.|...|
KIMKKNQIEQIKQEIHIMREINCFYKKINEKNILEQLNHPNIIKMYECFQEKDDNNIYLVMEYCQGGDLFDYIKNNKKKRNHEIEKDKYFTEKEIKYIMK

QIVA---------------GVDYCHRNL-VAHRDLKLENILIDDNNNIKIADFGLSNIMND-----------GKYLSTS---------------------
||.                .. |.| .  . |||.|.||||.     |||.||||| . .|           ..|.  .                     
QILQGFKTKAEFYIACIILALEYLHSKNNIIHRDIKPENILF-----IKIIDFGLSKKYDDDNQNRTHKQQCKWYMF-KNDTSRTPGYMDQIIQQNMFNT

-CGSPNYAAPEVISGKLY--------CGTEVDTWSCGVILFALLGGYLPFDEEVIPALYKKIKA----FFSPE-------------AH--------DIIK
 ||.|.| |||...|| |         ....| ||.||||. .| |..||        ...||     |..||              .        |.||
ICGTPGYMAPEILNGKKYDNQQKQKGYDYKCDIWSLGVILYEMLFGKPPF--------QQQIKQCKIDFPCPEWQKDTQCIQCKWKSWKKWSQECKDLIK

R----MLRPNPIERIK-FHELRLHPWL
.    ||  .| .||  . ..  |||.
KFGKRMLQKDPEKRITGWEQILNHPWF

Kinase 20428.AA TyrKc 15-308 21 1e-15 31.24 SMART 1-280 (280) Show / Hide
Range on Protein: 15-308
Range on HMM: 1-280/280
Sequence Identity: 21% (72 aa)

YLVGKTLGCGASGKVKREQFRLFKLTFFRGVQFTLLINQSSLSSENAKIFSKKSEFKNIFCFIIVAKHDITGKEVAIKIINKKKMTVKKMSNKIKREIRL
   ||.||.|| |.| . . .                                                    .||.| ... .         . ||.|.
ITLGKKLGEGAFGEVYKGTWK---------------------------------------------------IQVAVKMLKEDA------REDFMREARI

LRFF--NHQNIIRLYEVLDTN-------TDIFVVTEYISGGDLYDVIASKGK-LPEQEAKRYFKQIVAGVDYCHRNLVAHRDLKLENILIDDNNNIKIAD
.. .  .|.||.||| |  .          ...|.|| ..||| | . .... |. ..   .  || .| .| |.. . ||||   |.|...|. .||.|
MCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPHGDLKDYLRKHRPKLCMKDLLSFCWQIACGMEYLHSKNCIHRDLAARNCLVGENHTVKISD

FGLSNIMNDG-------KYLSTSC--GSP-----NYAAPEVISGKLY-CGTEVDTWSCGVILFALL-GGYLPFDE-----EVIPALYKKIKAF-------
||||    |.       .| ...   |.         |||.|  . . . |. | || || .. ..  |  |  .          .....|.        
FGLSRDIYDDDQQGESKDYYRKKEHKGGKTMLPIRWMAPECI--NYGKFTTKSDVWSFGVCMWEIFTYGQQPYPGMIQQMMSNQEVIEYVKQGYRMPQPP

---------FSPEAHDIIKRMLRPNPIERIKFHELRLHPWL
          ..| ..|.|.  . .| .|  | |.  |  .
NDYPMSFVCCPDEMYQIMKQCWHEDPEDRPTFSEI--HECF

Kinase 20428.AA Pkinase_Tyr 85-222 30 2e-15 52.88 Pfam 27-174 (270) Show / Hide
Range on Protein: 85-222
Range on HMM: 27-174/270
Sequence Identity: 30% (46 aa)

TGKEVAIKIINKKKMTVKK-MSNKIKREIRLLRFF-NHQNIIRLYEVLD-TNTD--IFVVTEYISGGDLYDVIAS----KGKLPEQEAKRYFKQIVAGVD
|. .||.|.. | . . .  .. .  ||..... . .|.||.||| |         |..|.||  .|||.|   .    |..|. ..   .  || .| .
TKIPVAVKML-KEGAMHEQNCREDFMREAKIMKQLGHHPNIVRLYGVCTDQGEPNQIYIVMEYMPHGDLLDYLRKHREDKQPLTMKDLLQMCWQIAKGME

YCHRNLVAHRDLKLENILIDDNNNIKIADFGLSNIM-NDGKY-LSTSCG
| ...   ||||   |.|...|| .||.||||.  . ||. |  ... |
YLESKNCIHRDLAARNCLVTENNVVKICDFGLARDIYNDDYYYRKRGGG

Kinase 20428.AA MARK 15-30 50 1.7e-05 14.09 In-house 1-16 (262) Show / Hide
Range on Protein: 15-30
Range on HMM: 1-16/262
Sequence Identity: 50% (8 aa)

YLVGKTLGCGASGKVK
| ..||.|.|. .|||
YKMLKTIGHGSYAKVK

Kinase 20428.AA BRSK 15-30 56 0.000416 9.87 In-house 1-16 (254) Show / Hide
Range on Protein: 15-30
Range on HMM: 1-16/254
Sequence Identity: 56% (9 aa)

YLVGKTLGCGASGKVK
| ..|||| |  |.||
YRLEKTLGKGQTGLVK

Kinase 20428.AA NuaK 15-31 58 0.001967 4.29 In-house 1-17 (252) Show / Hide
Range on Protein: 15-31
Range on HMM: 1-17/252
Sequence Identity: 58% (10 aa)

YLVGKTLGCGASGKVKR
| . |||| |  ||||.
YEFQKTLGKGTYGKVKL

Kinase 20428.AA GIN4 15-30 50 0.002402 6.07 In-house 1-16 (293) Show / Hide
Range on Protein: 15-30
Range on HMM: 1-16/293
Sequence Identity: 50% (8 aa)

YLVGKTLGCGASGKVK
. .|.||| |..|||.
WKLGETLGFGSTGKVQ

Kinase 20428.AA GIN4 79-106 39 0.02561 2.73 In-house 17-44 (293) Show / Hide
Range on Protein: 79-106
Range on HMM: 17-44/293
Sequence Identity: 39% (11 aa)

VAKHDITGKEVAIKIINKKKMTVKKMSN
.||.  ||.. |.|.| |||. ..   |
LAKNMETGQRAAVKVISKKKIFNHCNNN

Kinase 20428.AA Pkinase 15-31 35 1.223863 3.34 Pfam 1-17 (293) Show / Hide
Range on Protein: 15-31
Range on HMM: 1-17/293
Sequence Identity: 35% (6 aa)

YLVGKTLGCGASGKVKR
| .|...| |..|.|..
YHIGRKIGSGSFGCVYK

Kinase 20428.AA NuaK 425-438 50 0.077208 0.01 In-house 2-15 (252) Show / Hide
Range on Protein: 425-438
Range on HMM: 2-15/252
Sequence Identity: 50% (7 aa)

EEEEILGQWTYGKI
| .. ||. ||||.
EFQKTLGKGTYGKV