Gene 4451 (Tetrahymena)

4451

Species: Tetrahymena
Alias: 128.m00129, 3676.m00054, TTHERM_00773600, PreTt04451, 4451, 683
External Links: Tetrahymena Genome Database (TGD)
Annotation:

Classification

Group: CAMK
Family: CAMKL
Subfamily: AMPK

Sequence

Name Sequence Type Origin Length Description Download
4451.AA Protein None 1468 None Fasta, JSON
4451.NA RNA None 4407 None Fasta, JSON
4451.kin_dom Protein Kinase Domain None 253 None Fasta, JSON

Protein domain

Protein domains of 4451.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Kinase 4451.AA AMPK 22-274 67 2.2e-219 657.87 In-house 1-254 (254) Show / Hide 
Range on Protein: 22-274
Range on HMM: 1-254/254
Sequence Identity: 67% (172 aa)

YIIGQNIGEGTFGKVKLGTHIETREKVAIKILEKDKITEQADVERVAREIHILKILRHPNIIQLYEII-ETQKQLYLIMEYAQGGELFDYIVKNQKINER
||||..||||||||||.|||| |.||||||||.|.||..|..|||..|||||||..|||.||||||.| ||.......|||..||||||||||.....||
YIIGKTIGEGTFGKVKMGTHILTGEKVAIKILNKQKIKDQDMVERIQREIHILKLFRHPHIIQLYEVIIETPTDIFMVMEYVSGGELFDYIVKHGRLQER

ESCKYIQQILSGVEYLHNLNIAHRDLKPENLLLDHQKNIKIVDFGLSNLYKEGELLKTACGSPCYAAPEMIQGKKYEGLCVDIWSTGIIMFALICGYLPF
|.|...|||.|||||.|...|.|||||||||||||.||||||||||||..|.||.||||||||||||||||.||.|.|..|||||.|.|..|..||||||
EACRFFQQIISGVEYCHRHMIVHRDLKPENLLLDHNKNIKIVDFGLSNMMKDGEFLKTACGSPCYAAPEMISGKLYCGPEVDIWSCGVILYAMLCGYLPF

EDQNTSVLYKKIVSGEFSIPRWVSTEAKDLLNCILNTDPVKRYKINDIRNHKWY
.|.||..|||||..||..||...|.|||||....|..||.||..|.|||||.|.
DDENTPTLYKKIKNGEYYIPKFLSPEAKDLIKHMLQVDPMKRITIHDIRNHPWF
Kinase 4451.AA CAMKL 22-274 46 3.1e-157 505.45 In-house 1-297 (297) Show / Hide 
Range on Protein: 22-274
Range on HMM: 1-297/297
Sequence Identity: 46% (141 aa)

YIIGQNIGEGTFGKVKLGTH-IETREKVAIKILEKDKITE-------------QADVERVAREIHILKILR---HPNIIQLYEIIETQKQ------LYLI
|.||. .|.|.||||||.|| . |.|||||||..|.||..             ..|. |. |||.|.| |.   |||||.|||.|||..       .||.
YRIGKTLGKGSFGKVKLATHIRTTGEKVAIKIIDKKKIWNDPWMKKNKCGQKHESDM-RIRREIQIMKMLNIGKHPNIIKLYEVIETPEHDIETKKIYLV

MEYAQGGE--LFDYIVKN----QKINERESCKYIQQILSGVEYLHNLNIAHRDLKPENLLLDHQK--NIKIVDFGLSNLYKE-----GELLKTACGSPCY
|||..|||  |||||||.    ... |.| ..| .||.|.|.|.|...|.|||.||||.|||...  ||||.|||.||.|..     |..||| ||||.|
MEYCSGGEMDLFDYIVKHGHRRGRMPEHEARRYFRQIVSAVNYCHSHGIVHRDIKPENILLDENGNNNIKIIDFGFSNMYRPCIFGPGQKLKTFCGSPPY

AAPEMIQG--KKYEGLCVDIWSTGIIMFALICGYLPFEDQ--------NTSVLYKKIVSGEFSIPRW--VSTEAKDLLNCILNTDPVKRYKINDIRNHKW
.|||..||  |.|.|  ||||| |.|..|..||||||.|.        |.  ||.|| .| . .| |  || ...||.  .|...| ||..| .|.||.|
MAPEIFQGNNKPYDGPKVDIWSCGVILYAMVCGYLPFDDDTYNKQGKDNI-YLYWKIMCG-YYPPIWYHVS-DCRDLIRKMLQVNPEKRPTIHQIMNHPW

Y
.
M
Kinase 4451.AA CAMK 27-274 29 5.69999999999e-137 444.24 In-house 1-425 (425) Show / Hide 
Range on Protein: 27-274
Range on HMM: 1-425/425
Sequence Identity: 29% (125 aa)

NIGEGTFGKVKLGTHIETR------------EKVAIKILEKDKITE-------------------------QADVERVAREIHILKI-------LRHPNI
 .|.|.||||||..|..|             .||||||..|.|...                         . | ..| |||.|.|        |.||||
TLGRGSFGKVKLCIHKNTTGKERVHHIYTNGQKVAIKIIDKKKLKDKQNQDYSNCYKIDKSKCKHRYCWRRPKDRKNVRREIEIMKKLQGIGNKLDHPNI

IQLYEIIE------------TQKQ--------LYLIM---EYAQGGEL----FDYIVKN---------------QKINERESCKYIQQILSGVEYLHNLN
|.|||..|            | ..        .|..|   ||..||||    |||||..                ...||| ..|..||.|.|.|.|..|
IKLYEVYEDPHYFKNTNDYET-SKQVFTKDKHMYMVMEIMEYCSGGELFDDLFDYIVEHGCYGEEFDQFDIVERGRFTEREARRYFRQICSAVHYCHSHN

IAHRDLKPENLLLDHQK-----------------NIKIVDFGLSNLYKE------------------------GELLKTACGSPCYAA-PEMIQG-----
|.||||||||.|||. .                 ||||.|||..| ...                        |...|| ||.|.|.| ||...|     
IVHRDLKPENILLDDNNDDSDPVEHDEIFDWNNNNIKIIDFGFANKFDPGENNFMCSDYKGGEMHNQWTTPTEGQKMKTFCGTPEYMAAPEVLNGKGHCN

--------KKYEGLCVDIWSTGIIMFALICGYLPFEDQ-------------NTSVLYKKIVSGEFS-IPRW-----------------------VSTEAK
        |.| |  .|.|| |.|.... |||.||..              | . |..|| .|... .| .                       ||.|.|
MQNATDEEKPYYGPKCDMWSCGVILYIMLCGYPPFYGDCDNEICEDEWIGMNDYELFEKIMKGKYDFPPPYFSPISCNYGPEWWDDISDEFHHFVSQECK

DLLNCILNTDPVKRYKINDIRNHKWY
||....|..|| ||..| .. ||.|.
DLIRKMLQVDPEKRMTIEQCLNHPWM
Kinase 4451.AA MARK 22-274 45 3.8e-121 397.65 In-house 1-262 (262) Show / Hide 
Range on Protein: 22-274
Range on HMM: 1-262/262
Sequence Identity: 45% (120 aa)

YIIGQNIGEGTFGKVKLGTHIETREKVAIKILEKDKITE-QADVERVAREIHILKILRHPNIIQLYEIIE--TQKQ-LYLIMEYAQGGELFDYIVKN--Q
| ... ||.|...||||..|. |..||||||.|| |... |.  . | |||.|.| | |||||.|...||  | .. .||||||| ||||.|||..    
YKMLKTIGHGSYAKVKLACHKHTGRKVAIKIYEKFKLNDPQWM-KNVMREIEIMKKLDHPNIIKLFHVIEQDTEQHQIYLIMEYASGGELYDYIKAHPNG

KINERESCKYIQQILSGVEYLHNLNIAHRDLKPENLLLDHQK--NIKIVDFGLSNLYKEGELLKTACGSPCYAAPEMIQGKKYEGLCVDIWSTGIIMFAL
.. |.|  .. .||.|.|.|.|. ||.|||.||||.|.|...  |||| |||.|.  ..|..|.| ||.| |.|||....|.|.|  ||||| |......
RLHEEEARRIFRQIVSAVNYCHSKNIVHRDIKPENILIDENGNHNIKIIDFGFSICIPPGQKLNTFCGTPPYMAPEIFLKKPYDGPKVDIWSLGVVLYFM

ICGYLPFEDQN--TSVLYKKIVSGEFSIPRWVSTEAKDLLNCILNTDPVKRYKINDIRNHKWY
.|||.||....     |||||..|...||  ||.|...|.. .|...| .| .| .| .|.| 
VCGYFPFDGDTQDYKELYKKILRGKYDIPCHVSKECRNLIQRLLTVNPEERPTIEEIMKHPWM
Kinase 4451.AA QIK 22-274 43 2e-119 403.06 In-house 1-272 (272) Show / Hide 
Range on Protein: 22-274
Range on HMM: 1-272/272
Sequence Identity: 43% (118 aa)

YIIGQNIGEGTFGKVKLGTHIETREKVAIKILEKDKITEQADVERVAREIHILKILRHPNIIQLYEIIETQKQLYLIMEYAQGGELFDYIVKNQK-----
| |.. || | |. |||..|. | .||||||. | ...|. . ... ||. |.| |.||.|| ||...||.. .|...||...||.|||..|. .     
YDIERTIGKGNFAVVKLARHRITKTKVAIKIIDKSQLDEE-NLQKCYREVQIMKMLYHPHIIKLYQVMETDDMMYIVTEYCSNGEMFDYLCKHGRKGVKM

---------------INERESCKYIQQILSGVEYLHNLNIAHRDLKPENLLLDHQKNIKIVDFGLSNLYKEGELLKTACGSPCYAAPEMIQGKKYEGLCV
               ..|.|  .  .||.|.|.|.|..||.||||| ||.||| . ||||.|||.||..|.|.||.| |||| |||||| .||.|.|  |
VNSPDIGDQVLMGVPMAENEARRWFWQICSAVHYCHKRNIVHRDLKAENILLDNNMNIKIADFGFSNWFKQGQLLMTWCGSPPYAAPEMFEGKEYDGPKV

DIWSTGIIMFALICGYLPFEDQNTSVLYKKIVSGEFSIPRWVSTEAKDLLNCILNTDPVKRYKINDIRNHKWY
|||| |.....|.|| |||  ..   | ....|| | || ..|..  .|    |  || .|| |. |..|.| 
DIWSMGVVLYVLVCGALPFDGKTLQNLRQRVLSGKFRIPFFMSQDCEHLIRHMLVVDPEHRYTIMQICQHRWM
Kinase 4451.AA NuaK 22-274 43 1.1e-116 308.34 In-house 1-252 (252) Show / Hide 
Range on Protein: 22-274
Range on HMM: 1-252/252
Sequence Identity: 43% (109 aa)

YIIGQNIGEGTFGKVKLGTHIETREKVAIKILEKDKITEQADVERVAREIHILKILRHPNIIQLYEIIETQKQLYLIMEYAQGGELFDYIVKNQKINERE
| . .  |.||.|||||.| ..|  .||||   |.|| ...|  .. ||| |.  | ||.||. ||. | .  . ..|||| ||||.||| . ... |||
YEFQKTLGKGTYGKVKLATEHSTGREVAIKSIKKCKIEDEQDMVHIRREIEIMSSLNHPHIIHIYEVFENKDKIVIVMEYASGGELYDYISECKSLPERE

SCKYIQQILSGVEYLHNLNIAHRDLKPENLLLDHQKNIKIVDFGLSNLYKEGELLKTACGSPCYAAPEMIQGKKYEGLCVDIWSTGIIMFALICGYLPFE
  .   || | | | |  .|.||||| || ||| . |.|| ||||||.|.....|.| |||| || || . |. |.|  || || |....... | .||.
ARHFFRQIVSAVHYCHKHRICHRDLKLENILLDQNCNAKIADFGLSNYYHDQKFLHTFCGSPLYASPEIVNGQPYHGPEVDCWSLGVLLYTMVYGTMPFD

DQNTSVLYKKIVSGEFSIPRWVSTEAKDLLNCILNTDPVKRYKINDIRNHKWY
 ..   | | | .|..  |.  |. |  |   .|  .| .|  | || .| | 
GHDFKHLVKQISQGAYYEPCKPSD-ACMLIRWMLMVNPRRRATIYDICHHWWV
Kinase 4451.AA CAMK1 22-274 41 1.1e-112 328.85 In-house 1-276 (276) Show / Hide 
Range on Protein: 22-274
Range on HMM: 1-276/276
Sequence Identity: 41% (116 aa)

YIIGQNIGEGTFGKVKLGTHIET---REKVAIKILEKDKITEQADV---ERVAREIHILK---ILRHPNIIQLYEIIETQKQLYLIMEYAQGGELFDYIV
|..|  ||.|.|..|.|.||.||    ...|||...| | ... |.   |.. .|| |.|    . |||||..||. |. . .||.||. .|||||| ||
YEFGKEIGRGAFSEVYLCTHKETQTNGKQYAIKCIDKKKFMKKKDMQKQEALENEIEIMKKVSKIDHPNIIKFYEWYESDNHFYLVMELVTGGELFDRIV

KNQKINERESCKYIQQILSGVEYLHNLNIAHRDLKPENLLLDHQ-KN--IK--IVDFGLSNLYKEGE-LLKTACGSPCYAAPEMIQG---KKYEGLCVDI
.. . .|.. .. ..|||| |||.| ..|.||||||||||.  .  .  ||  | |||||  ....| |.|||||.| | |||.. .   | | .  .|.
EKGNYTEKDARHIMKQILSAVEYMHSKGIVHRDLKPENLLYYDKDEDSKIKRSIADFGLSKIFDHDENLMKTACGTPGYVAPEVLECKKDKPY-DKACDM

WSTGIIMFALICGYLPFEDQN-TSVLYKKIVSGEFSIPRW----VSTE-AKDLLNCILNTDPVKRYKINDIRNHKWY
|| |.| . | ||| || | |  . |..|| ..|.  |      .| . |||.... |. || ||| . .. ||.| 
WSIGVITYILLCGYPPFYDENVDNELFEKIKKCEYEFPSPWWDNISDQEAKDFIKHMLEVDPKKRYTCEQCLNHPWI
Kinase 4451.AA S_TKc 22-274 38 1.4e-106 361.35 SMART 1-231 (231) Show / Hide 
Range on Protein: 22-274
Range on HMM: 1-231/231
Sequence Identity: 38% (102 aa)

YIIGQNIGEGTFGKVKLGTHIETREKVAIKILEKDKITEQADVERVAREIHILKILRHPNIIQLYEIIETQKQLYLIMEYAQG--GELFDYIVKNQK---
| |.. ||.|.||||....|..| ..|||||.           |.. ||| |||  .||||..||..... . ||..|||. |  |.|||||.|...   
YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK----------EHIRREIQILKK-HHPNIVKLYDVFQD-DHLYMVMEYCDGDLGDLFDYIKKRGRHGL

---INERESCKYIQQILSGVEYLHNLNIAHRDLKPENLLLDHQKNIKIVDFGLSNLYKEGELLKTACGSPCYAAPEMIQGKKYEGLCVDIWSTGIIMFAL
   ..| . ..|..||....||.|...| ||||||||.|||.  .||| ||||. ..      .| ||.| | |||..   .| .  .|.|| |.|.. .
RFPFPE-HARFYMYQICCALEYCHSHGIIHRDLKPENILLDE--HIKICDFGLARQL------TTFCGTPWYMAPEVL---GYGKCKCDWWSCGCILYEM

ICGYLPFEDQNTSVLYKKIVSGEFSIPRWVSTEAKDLLNCILNTDPVKRYKINDIRN-------HKWY
.||| ||.  .  ...|||.          | ||||... .|. || ||. . .. .       | | 
LCGYPPFP--QMQMMFKKIG----------SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF
Kinase 4451.AA BRSK 22-274 45 6.30000000001e-106 358.22 In-house 1-254 (254) Show / Hide 
Range on Protein: 22-274
Range on HMM: 1-254/254
Sequence Identity: 45% (115 aa)

YIIGQNIGEGTFGKVKLGTHIETREKVAIKILEKDKIT-EQADVERVAREIHILKILRHPNIIQLYEIIETQKQLYLIMEYAQGGELFDYIVKNQKINER
|...   | |. |.||||.|  | .||||||  | |         .| ||| |.|   ||.....|.. |..| ||||.|. .||||||| ||  .   .
YRLEKTLGKGQTGLVKLGVHCVTGKKVAIKIINKEKLSNKESMLMKVEREIAIMKLIDHPHVMKMYDVYENKKYLYLILEHVSGGELFDYLVKKGRLTPK

ESCKYIQQILSGVEYLHNLNIAHRDLKPENLLLDHQKNIKIVDFGLSNLYKEGELLKTACGSPCYAAPEMIQGKKYEGLCVDIWSTGIIMFALICGYLPF
|  |. .|| |.... |  || |||||||||||| ..|||| |||.  |  .. .| | |||| || || |.| || |   |.|| |.|..||  | |||
EARKFFRQIISALDFCHSHNICHRDLKPENLLLDEKNNIKIADFGMASLQVKDMMLHTSCGSPHYACPEVIRGEKYDGRKADVWSCGVILYALLVGALPF

EDQNTSVLYKKIVSGEFSIPRWVSTEAKDLLNCILNTDPVKRYKINDIRNHKWY
 | |   |  |.  | |..| ..   . |||   .  || ||. ...|. | ||
DDDNLRQLLEKVKRGVFHMPHFIHPDCQDLLRGMIEVDPDKRISLKEIQKHPWY
Kinase 4451.AA RAD53 22-274 38 2.3e-103 308.76 In-house 1-305 (305) Show / Hide 
Range on Protein: 22-274
Range on HMM: 1-305/305
Sequence Identity: 38% (116 aa)

YIIGQNIGEGTFGKVKLGTHIETREKVAIKILEKDK-----ITEQADVERVAREIHILKILRHPNIIQLYEIIET-QKQLYLIMEYAQGGELFDYIVKNQ
|...  .| | ||.|||.   .|..||||||..| |      ..... ..| .|. ||| | ||.||..|.|..| ||..|...|.. |||||. || | 
YYMSKELGSGNFGTVKLAYEKKTCQKVAIKIIDKKKFFIRCMHTIKKMDQVMNEVEILKKLNHPCIIRIYDIFDTPQKYYYMVLELMTGGELFNKIVSNK

K----INERESCKYIQQILSGVEYLHNLNIAHRDLKPENLLLDHQK------------------NIKIVDFGLSNLYKEGELLKTACGSPCYAAPEMIQG
.     .| ..  |  |.. .| |||...|.|||||||| |..||.                   ||| |||||    ||...|| ||.| | ||| | .
RCQMGFDEDTCKYYFYQMCDAVKYLHDNGICHRDLKPENILCNHQDEECPQVQLGPWDEDEISFLIKITDFGLSKFVGEGSFMKTMCGTPQYVAPEVITS

K------KYE--------GLCVDIWSTGIIMFALICGYLPFEDQ-----NTSVLYKKIVS-GEFSI--PRW--VSTEAKDLLNCILNTDPVKRYKINDIR
|       .|        .  ||.|| | | . . |||.|| |.      .  |...|.. | ..   | |  .| ||||| .  |. || ||| |... 
KGHNCYHENEERQVQVGYTKKVDCWSMGCILYICLCGYPPFSDDYTQEMHCMQLFEQIKNQGKYHFPHPYWDRISEEAKDLIKWMLCVDPEKRYTIDEAL

NHKWY
|| | 
NHPWM
Kinase 4451.AA Pkinase 22-274 34 1e-100 345.71 Pfam 1-293 (293) Show / Hide 
Range on Protein: 22-274
Range on HMM: 1-293/293
Sequence Identity: 34% (103 aa)

YIIGQNIGEGTFGKVKLGTHIETREKVAIKILEKDKITEQADVERVA-REIHILKILRHPNIIQLYEIIETQKQLYLIMEYAQGG----ELFDYIV--KN
| ||. ||.|.||.|....|. |...||.||..|... .. |....  .||.|.| |.||||..||.. |. . .|..|||..||    .|||||   ..
YHIGRKIGSGSFGCVYKCHHKGTGKIVAVKIIKKRHEKSWKDQTHRRLSEIQIMKRLNHPNIVRLYDWFEDKDHIYMVMEYCEGGLYVMDLFDYISTWRH

QKI--NERESCKYIQQILSGVEYLHNLNIAHRDLKPENLLLDHQKNI----KIVDFGLSNL--YKEGELLKTACGSPCYAAPEMIQGKKYEGLCVDIWST
 ..   |.| ..|. |||.|.||.|. .| ||||||||.|.|.. .|    || ||||. .  |  .. ..| ||.| |.||| |.| .| |  ||.|| 
GCFYFSEWECKFYMYQILRGLEYCHSMGIIHRDLKPENILIDNNGHIDACVKICDFGLAKQFDY-NNS-MTTFCGTPWYMAPEVIRGGQYYGPKVDMWSC

GIIMFALICGYLPFEDQ------NTSVLYKKIVSGEFSIPRWVS---------------------TEAKDLLNCILNTDPVKRYKINDIRNHKWY
|.|.. ..||..|| ..      .  .....| ..... ... .                      |.||.....|. || ||. . .| .|.| 
GCILYEMLCGRPPFPGHCWHDNHDQMQMICRIMGPPLHFDWPWWCSISYFFFRHWHFHWTFHNWSEECKDFIKWCLCKDPKKRPTAEQILQHPWF
Kinase 4451.AA MELK 22-274 46 5.1e-97 328.61 In-house 1-254 (254) Show / Hide 
Range on Protein: 22-274
Range on HMM: 1-254/254
Sequence Identity: 46% (120 aa)

YIIGQNIGEGTFGKVKLGTHIETREKVAIKILEKDKITEQADVERVAREIHILKILRHPNIIQLYEIIETQKQLYLIMEYAQGGELFDYIVKNQKINERE
| . ..|| | |.|||| .|| | ..|||||..|... .  |. ||  |.. || ||| .| ||| .|||.......|||  |||.||||.......| |
YEVHDEIGTGGFAKVKLACHILTNQMVAIKIMDKNQLGH--DLPRVKTEMDALKNLRHQHICQLYHYIETEDKIFMVMEYCPGGEMFDYIIRQDRLEEEE

SCKYIQQILSGVEYLHNLNIAHRDLKPENLLLDHQKNIKIVDFGLSNLYK---EGELLKTACGSPCYAAPEMIQGKKYEGLCVDIWSTGIIMFALICGYL
. .. .||.| . |.|    |||||||||||.| ....|..||||    |   .   |.| |||| |||||.||||.| |   |.|| ||....|.||.|
TRHFFRQIVSAIAYVHSQGYAHRDLKPENLLFDEDHHLKLIDFGLCAKTKGRKDYHNLQTCCGSPAYAAPELIQGKQYIGSEADVWSMGILLYVLMCGFL

PFEDQNTSVLYKKIVSGEFSIPRWVSTEAKDLLNCILNTDPVKRYKINDIRNHKWY
||.| | ...||||.|| .  |.|.| |.|.||  .|  || || .. .. || | 
PFDDDNMMIMYKKIMSGCYEEPKWLSPESKQLLRHMLQVDPKKRISMKNLLNHPWV
Kinase 4451.AA Pkinase_Tyr 22-167 35 2.4e-31 106.76 Pfam 1-158 (270) Show / Hide 
Range on Protein: 22-167
Range on HMM: 1-158/270
Sequence Identity: 35% (56 aa)

YIIGQNIGEGTFGKVKLGTHI----ETREKVAIKILEKDKITEQAD--VERVAREIHILKIL-RHPNIIQLYEIIE-TQKQ--LYLIMEYAQGGELFDYI
 ..|. .||| ||.|..||      .|. .||.|.| |.  . . .   |   ||. |.| | .||||..|| ..   ...  .|..|||...| | || 
ITFGKKLGEGAFGEVYKGTWKGDPDNTKIPVAVKML-KE-GAMHEQNCREDFMREAKIMKQLGHHPNIVRLYGVCTDQGEPNQIYIVMEYMPHGDLLDYL

VK----NQKINERESCKYIQQILSGVEYLHNLNIAHRDLKPENLLLDHQKNIKIVDFGLS
 |    .|...  . ... .|| .| |||.. |. ||||   | |..... .|| ||||.
RKHREDKQPLTMKDLLQMCWQIAKGMEYLESKNCIHRDLAARNCLVTENNVVKICDFGLA
Kinase 4451.AA TyrKc 22-275 25 1.5e-22 82.14 SMART 1-280 (280) Show / Hide 
Range on Protein: 22-275
Range on HMM: 1-280/280
Sequence Identity: 25% (75 aa)

YIIGQNIGEGTFGKVKLGTHIETREKVAIKILEKDKITEQADVERVAREIHILKIL--RHPNIIQLYEIIETQ-------KQLYLIMEYAQGGELFDYIV
   |. .||| ||.| .|| .   ..||.| | .|.      .|   ||. |.. |  .||||..|| .. .|       ..|...|||. .| | ||. 
ITLGKKLGEGAFGEVYKGTWK---IQVAVKMLKEDA------REDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPHGDLKDYLR

KNQK-INERESCKYIQQILSGVEYLHNLNIAHRDLKPENLLLDHQKNIKIVDFGLSNLYKEG-------ELLKTAC--GSP--C---YAAPEMIQGKKYE
|... .. .. ...  || .| ||||  |. ||||   | |..... .|| |||||   ...       .  ...   |.         ||| |. .|. 
KHRPKLCMKDLLSFCWQIACGMEYLHSKNCIHRDLAARNCLVGENHTVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGKTMLPIRWMAPECINYGKF-

GLCVDIWSTGIIMF-ALICGYLPFED-----QNTSVLYKKIVSGEFSIPRWV---------STEAKDLLNCILNTDPVKRYKINDIRNHKWYL
    |.|| |. |.  .  |  | ..      . . ..... .|.   .            ..|  ..  .  . || .|   ..|   . ..
TTKSDVWSFGVCMWEIFTYGQQPYPGMIQQMMSNQEVIEYVKQGYRMPQPPNDYPMSFVCCPDEMYQIMKQCWHEDPEDRPTFSEI---HECF
UBA_CAMKL 4451.AA UBA_CAMKL 288-325 36 7.9e-11 37.05 In-house 1-41 (41) Show / Hide 
Range on Protein: 288-325
Range on HMM: 1-41/41
Sequence Identity: 36% (15 aa)

NEAILQKLKDF--NIDLDVARKCIESNKH-NDITTTYYLLL
.| |.| ..    ..| .  ......||. |.||.||||||
DEEIIQEMCKMWHGFDREEIIESLRNNKYHNHITATYYLLL