Gene 10181 (Tetrahymena)

10181

Species: Tetrahymena
Alias: PreTt10181, 10181, TTHERM_00079350, 3828.m01443, 5.m00532, 135
External Links: Tetrahymena Genome Database (TGD)
Annotation:

Classification

Group: CAMK
Family: CAMKL
Subfamily: CAMKL-Unclassified

Sequence

Name Sequence Type Origin Length Description Download
10181.AA Protein None 389 None Fasta, JSON
10181.NA RNA None 1170 None Fasta, JSON
10181.kin_dom Protein Kinase Domain None 241 None Fasta, JSON

Protein domain

Protein domains of 10181.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Kinase 10181.AA CAMKL-Unclassified 99-339 52 3.9e-184 618.03 In-house 1-290 (290) Show / Hide 
Range on Protein: 99-339
Range on HMM: 1-290/290
Sequence Identity: 52% (152 aa)

YEILQTIGEGGFGKVVLAEHKQTKEKFAIKFVNTSLIGNASDIDMVFREAEG--------------------MEVVFIMEYLQGGELLEYVTKKGRLSEL
|.|.|.|||||||.|.|||||||.||||||||.|...|.|.||||||||||.                    |.||.|||||||||||....|.|...|.
YNIVQVIGEGGFGQVQLAEHKQTQEKFAIKFVKTMNHGCAMDIDMVFREAEILKSLNHKNIVKIKNCYTLSDMKVVMIMEYLQGGELLDWCRKNGHFNEN

EAR-------QFFRQIVDAIQYCHKENVIHRDLKLENILLSQSSSSSIIKIIDFGIAGVGN--LNTNKLNVGSLRYMAPEVLLKQVQSLQKSIDIWSLGV
.||       |.|.|||||.|||||...|||||||||.||.|..||..|||.|||||||.|  .|....|.|||||||||....||...|.|||||..||
NARRQPWEIQQYFQQIVDAMQYCHKNCIIHRDLKLENVLLRQQDSSPVIKIFDFGIAGVANVNQNVFNINGGSLRYMAPEMKNQQVKQIQYSIDIWAMGV

ILYTLVVGNLPFNG---------------ETPSEIIKKITTGSYSFPAQVEGILTDEIKD-----LITNILIVNPEKRFALKQIRQHEWM
.||...|...||||               .....|..|||.|.|.||.|....|.||.||     ||.||..|||..||...||.||.||
MLYMCIVQFFPFNGNGNNGKNNNSDGNENDNNNNIMFKITRGPYEFPEQINKPLPDECKDQRLISLIENIFQVNPKNRFTTHQIMQHPWM
Kinase 10181.AA CAMKL 99-339 35 1.6e-105 337.75 In-house 1-297 (297) Show / Hide 
Range on Protein: 99-339
Range on HMM: 1-297/297
Sequence Identity: 35% (106 aa)

YEILQTIGEGGFGKVVLAEH-KQTKEKFAIKFVNTSLIGNASDIDM------------VFREAEG---ME-------------------------VVFIM
|.|..|.|.|.|||| ||.| . |.|| |||... . | |   ...            ..||..    .                          .. .|
YRIGKTLGKGSFGKVKLATHIRTTGEKVAIKIIDKKKIWNDPWMKKNKCGQKHESDMRIRREIQIMKMLNIGKHPNIIKLYEVIETPEHDIETKKIYLVM

EYLQGGE--LLEYVTKK----GRLSELEARQFFRQIVDAIQYCHKENVIHRDLKLENILLSQSSSSSIIKIIDFGIA-----G-VGNLNTNKLNVGSLRY
|| .|||  |..|. |.    ||..| |||..|||||.|..|||. ...|||.|.|||||... ..  ||||||| .     . .|. .. |   ||. |
EYCSGGEMDLFDYIVKHGHRRGRMPEHEARRYFRQIVSAVNYCHSHGIVHRDIKPENILLDENGNN-NIKIIDFGFSNMYRPCIFGPGQKLKTFCGSPPY

MAPEVLLK-QVQSLQKSIDIWSLGVILYTLVVGNLPFNGETPS-------EIIKKITTGSYSFPAQVEGILTDEIKDLITNILIVNPEKRFALKQIRQHE
||||.... . .   . .||||.|||||..|.|.|||...| .       .  .|| .| | .|  ..  .  . .|||  .| ||||||. ..||..|.
MAPEIFQGNNKPYDGPKVDIWSCGVILYAMVCGYLPFDDDTYNKQGKDNIYLYWKIMCG-YYPPIWYH--VS-DCRDLIRKMLQVNPEKRPTIHQIMNHP

WM
||
WM
Kinase 10181.AA CAMK 104-339 25 8.9e-100 322.21 In-house 1-425 (425) Show / Hide 
Range on Protein: 104-339
Range on HMM: 1-425/425
Sequence Identity: 25% (107 aa)

TIGEGGFGKVVLAEHKQTK------------EKFAIKFVNTSLIGN-------------------------ASDIDMVFREAEGME--------------
|.|.|.|||| |..||.|.            .|.|||..... . .                         ..| ..|.|| | |               
TLGRGSFGKVKLCIHKNTTGKERVHHIYTNGQKVAIKIIDKKKLKDKQNQDYSNCYKIDKSKCKHRYCWRRPKDRKNVRREIEIMKKLQGIGNKLDHPNI

-------------------------------VVFIM---EYLQGGEL----LEYVTKK---------------GRLSELEARQFFRQIVDAIQYCHKENV
                               ....|   || .||||    ..|....               ||..| |||..||||..|..|||. |.
IKLYEVYEDPHYFKNTNDYETSKQVFTKDKHMYMVMEIMEYCSGGELFDDLFDYIVEHGCYGEEFDQFDIVERGRFTEREARRYFRQICSAVHYCHSHNI

IHRDLKLENILLSQSSSSS--------------IIKIIDFGIAGVGNLNTNKL-------------------------NVGSLRYMA-PEVLLKQ-----
.|||||.|||||......|               ||||||| | . . . | .                          .|.. ||| ||||...     
VHRDLKPENILLDDNNDDSDPVEHDEIFDWNNNNIKIIDFGFANKFDPGENNFMCSDYKGGEMHNQWTTPTEGQKMKTFCGTPEYMAAPEVLNGKGHCNM

-------VQSLQKSIDIWSLGVILYTLVVGNLPFNGE-------------TPSEIIKKITTGSYSFPAQV------------EGILTDE--------IKD
        .   ...|.||.|||||....| .||.|.             ...|. .||..| |.||                .  .||         ||
QNATDEEKPYYGPKCDMWSCGVILYIMLCGYPPFYGDCDNEICEDEWIGMNDYELFEKIMKGKYDFPPPYFSPISCNYGPEWWDDISDEFHHFVSQECKD

LITNILIVNPEKRFALKQIRQHEWM
|| ..| |.||||. ..|. .|.||
LIRKMLQVDPEKRMTIEQCLNHPWM
Kinase 10181.AA S_TKc 99-339 32 1.3e-79 271.7 SMART 1-231 (231) Show / Hide 
Range on Protein: 99-339
Range on HMM: 1-231/231
Sequence Identity: 32% (90 aa)

YEILQTIGEGGFGKVVLAEHKQTKEKFAIKFVNTSLIGNASDIDMVFREAEGME-----------------VVFIMEYLQG--GELLEYVTKKGR-----
||||..||.|.|||| .. || |....||| ..          ... || . ..                 . ..|||. |  |.|..|  |.||     
YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK----------EHIRREIQILKKHHPNIVKLYDVFQDDHLYMVMEYCDGDLGDLFDYIKKRGRHGLRF

-LSELEARQFFRQIVDAIQYCHKENVIHRDLKLENILLSQSSSSSIIKIIDFGIAGVGNLNTNKLNVGSLRYMAPEVLLKQVQSLQK-SIDIWSLGVILY
 ..| .|| ...||..|..|||. ..|||||| |||||..      |||.|||.| .      .  .|.. |||||||     .  | ..|.||.|.|||
PFPE-HARFYMYQICCALEYCHSHGIIHRDLKPENILLDE-----HIKICDFGLARQL-----TTFCGTPWYMAPEVL-----GYGKCKCDWWSCGCILY

TLVVGNLPFNGETPSEIIKKITTGSYSFPAQVEGILTDEIKDLITNILIVNPEKRFALKQIRQ-------HEWM
 ...|  ||   .. ...|||               ..| ||.| ..| ..||||    .. |       |.|.
EMLCGYPPFP--QMQMMFKKIG--------------SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF
Kinase 10181.AA Ciliate-E2-Unclassified 99-339 24 6.1e-73 248.64 In-house 1-352 (352) Show / Hide 
Range on Protein: 99-339
Range on HMM: 1-352/352
Sequence Identity: 24% (87 aa)

YEILQTIGEGGFGKVVLAEHKQTKEKF------AIKFVNTSLIGNASD------------------------------------IDMVFREAEGMEVVFI
|.|...||.|||||| ...||..| ..        . .. ... . .|                                    . |.. .     . ..
YKIIKQIGQGGFGKVYKCQHKKQK-QYYAMKYMKKIQIYKQKQIMNKDEIMNEMKEMNNKKKYHQRKYNKIMQQILLNHPHPFIVKMFYCFQDKQNIYIV

MEYLQGGELLEYVTKK-----------------GRLSELEAR-----QFFRQIVDAIQYCHKEN-VIHRDLKLENILLSQSSSSSIIKIIDFGIA-GVGN
|||..||.|..| .|.                  ...| .|.     ..|.||.....|.|..| .||||.|.||||.... .   ||||||||.   ..
MEYCEGGDLWQYIKKRKKQKQKGNDLFHNMKQRKIFTEQQAKYKKAKFYFAQILQGLEYLHHKNNIIHRDIKPENILFDNNGKNYYIKIIDFGISKKYQQ

LNTNKLN-----------------VGSLRYM----APEVLLKQVQSLQ--KSIDIWSLGVILYTLVVGNLPFNGETPSE----------------IIKKI
 | .. .                 .|...||    ||||| .| .. .  ...|||||||||| .. |..||....  .                ....|
NNNCD-TNQQQKMQIWKQQMMWTFCGTPNYMPQYTAPEVLQGQNYDHSKAYKCDIWSLGVILYEMLFGYYPFYDNNCEQHQQLITQWINNAYRKQLYQNI

TTGSYSFPAQVE----GILTDEIKDLIT----NILIVNPEKRFALKQIRQHEWM
  . ..|| . .     .. .| ||.|.     .| .||.||  ..|| .| |.
KQKNIQFPKFPWQQIPKHWSPEAKDFINDLLQKMLKKNPNKRITFEQILNHPWF
Kinase 10181.AA AGC 155-339 25 1.5e-71 183.36 In-house 110-395 (395) Show / Hide 
Range on Protein: 155-339
Range on HMM: 110-395/395
Sequence Identity: 25% (74 aa)

FIMEYLQ---------GG-ELLEYVT---KKGRLSELEARQFFRQ-------IVDAIQYCHK-ENVIHRD-LKLENILLSQSSSSSIIKIIDFGIAGVGN
|.|||..         || ||. .     |.||..| .|| .. .       || |..| |.  ..|||| ||.||||| .      ||. ||| . .|.
FVMEYMPRYVNDLYCGGGCELFLHLQGRRKEGRFDEERARFYAAEMQKICGCIVLALEYLHSHMGIIHRDYLKPENILLDED---GHIKLTDFGLCKEGM

L----------------------------------------------------NTNKLNVG--SLRYMAPEVLLKQVQSLQKSIDIWS--LGVILYTLVV
                                                     ....  .|  .  |||||.|        |. |.||  ||...| ...
NDGEKGQQSQSNMKFHWHNKKYQKSNMDTNKCNPNNWQRNNMSQEDDTTRKKRDRTWTFCGPCTPEYMAPEIL------YGKACDWWSFGLGCLMYEMLT

GNLPFNGETPS----------EIIKKITTGSYSFPAQVEGI------------LTDEIKDLITNILIVNPEKRFA----------LKQIRQHEWM
|  ||.|..|           |. .||  | | .. .|.              ...| ||||.  | ..||||             ..|..|.| 
GYPPFYGDNPQENRHPFRNPMEMFQKIMNGRYFINWKVKFPFPEDPQFPEDRWFSPEAKDLIKKLLCKDPEKRLGCGGNDFGDKGAEEIKNHPWF
Kinase 10181.AA Ciliate-E2a 155-339 34 1.6e-65 191.83 In-house 76-275 (275) Show / Hide 
Range on Protein: 155-339
Range on HMM: 76-275/275
Sequence Identity: 34% (69 aa)

FIMEYLQGGELLEYVTKKG-RLSE-LEARQFFRQIV-DAIQYCHKENVIHRDLKLENILLS-QSSSS---SIIKIIDFGIAGVG--NLN-TNKLNVGSLR
..|||..||||...  ...   .|  |.... .|.  ....|.|. |..|||||.||||.   |..|   | ||||||| |     . .   .  .|.  
LVMEYCEGGELYDKIKQCKRFFEEIQEICDIMQQLLWQGLHYMHQRNIMHRDLKPENILFKNCSKNSIQNSDIKIIDFGLATFIDKDEKKYMFQKCGTPG

YMAPEVLL-KQV---QSLQKSIDIWSLGVILYTLVVGNLPFNGETPSEIIKKITTGSYSFPAQV-EGILTDEIKDLITNILIVNPEKRFALKQIRQHEWM
|.|||||  |.|   ..  .. |.||.|||.|.|..| .||.|.| .||....    ..|  ..    ...| |||.   | ..|.||.  .|. .| |.
YVAPEVLNNKEVLKHKQYDTKCDMWSCGVIFYILLCGKPPFKGKTYNEILQQNKKCKIDFNCPECWEKCSKECKDLMKKMLEKDPKKRITAQQALNHPWF
Kinase 10181.AA CDPK 155-339 41 7.3e-65 197.95 In-house 78-271 (271) Show / Hide 
Range on Protein: 155-339
Range on HMM: 78-271/271
Sequence Identity: 41% (81 aa)

FIME--YLQGGELLEYVTKKGRLSELEARQFFRQIVDAIQYCHKENVIHRDLKLENILLSQSSSSS----IIKIIDFGIAGVGNLN----TNKLN--VGS
..||  |. ||||..|.. ||...| ||.. .|||. |..|||. |..||||| ||||. . ...|    .||.||.|..   . |     .|..  .| 
IVMETEYCTGGELFDYIIEKGHFTEKEAAYIMRQILSAVNYCHSNNIVHRDLKPENILFDSKKDDSWVIYNIKVIDWGTSKKFDQNQKIEDKKMSQRCGT

LRYMAPEVLLKQVQSLQKSIDIWSLGVILYTLVVGNLPFNGETPSEIIKKITTGSYSFPAQVEGILTDEIKDLITNILIVNPEKRFALKQIRQHEWM
  |.||||| |.     .. ||||.|||||.| .|  ||.|.. .||..|.  | |||  .   . .|| |||| . | ..|.||.   |. || |.
PYYIAPEVLQKK---YNEKCDIWSCGVILYILLCGYPPFYGKNDQEIMEKVKKGKYSFEGPEWDHISDEAKDLIRKMLCYDPKKRMSAQQALQHPWF
Kinase 10181.AA AMPK 156-339 42 6.7e-64 188.62 In-house 78-254 (254) Show / Hide 
Range on Protein: 156-339
Range on HMM: 78-254/254
Sequence Identity: 42% (79 aa)

IMEYLQGGELLEYVTKKGRLSELEARQFFRQIVDAIQYCHKENVIHRDLKLENILLSQSSSSSIIKIIDFGIAGVGNLNTNKLNV--GSLRYMAPEVLL-
.||| .|||| .|..|.|||.| ||. || ||. .. |||. .. |||||.||.||        ||| |||   . . . ..|    ||  | |||.   
VMEYVSGGELFDYIVKHGRLQEREACRFFQQIISGVEYCHRHMIVHRDLKPENLLLD---HNKNIKIVDFGLSNMMKDG-EFLKTACGSPCYAAPEMISG

KQVQSLQKSIDIWSLGVILYTLVVGNLPFNGETPSEIIKKITTGSYSFPAQVEGILTDEIKDLITNILIVNPEKRFALKQIRQHEWM
|   ...  .|||| ||||| .. | |||  |  ..  |||. | |. |. ..    .|.|||| ..| |.|.||.  ..||.|.| 
KLYCGPE--VDIWSCGVILYAMLCGYLPFDDENTPTLYKKIKNGEYYIPKFLS----PEAKDLIKHMLQVDPMKRITIHDIRNHPWF
Kinase 10181.AA Ciliate-E2 153-339 26 3.7e-63 215.66 In-house 109-365 (365) Show / Hide 
Range on Protein: 153-339
Range on HMM: 109-365/365
Sequence Identity: 26% (73 aa)

VVFIMEYLQGGELLEYVTKK-----------GRLSELEARQFFRQIVD---------------AIQYCHKEN-VIHRDLKLENILLSQSSSSSIIKIIDF
. ..|||.|||.|..|  ..           ....| |......||..               |..|.|..| .||||.|.||||.        ||||||
IYLVMEYCQGGDLFDYIKNNKKKRNHEIEKDKYFTEKEIKYIMKQILQGFKTKAEFYIACIILALEYLHSKNNIIHRDIKPENILF--------IKIIDF

GIAG-VGNLNTNKL--------------------------------NVGSLRYMAPEVLLKQV---QSLQ----KSIDIWSLGVILYTLVVGNLPFNGET
|..  . . | |..                                 .|.. |||||.| ..    |..|    ...|||||||||| .. |..||    
GLSKKYDDDNQNRTHKQQCKWYMFKNDTSRTPGYMDQIIQQNMFNTICGTPGYMAPEILNGKKYDNQQKQKGYDYKCDIWSLGVILYEMLFGKPPF----

PSEIIKKITTGSYSFPAQ--------------VEGILTDEIKDLITN----ILIVNPEKRFA-LKQIRQHEWM
    ...|  . ..|| .                  ...| |||| .    .| ..||||.   .|| .|.|.
----QQQIKQCKIDFPCPEWQKDTQCIQCKWKSWKKWSQECKDLIKKFGKRMLQKDPEKRITGWEQILNHPWF
Kinase 10181.AA Pkinase 152-339 30 1.5e-61 215.61 Pfam 74-293 (293) Show / Hide 
Range on Protein: 152-339
Range on HMM: 74-293/293
Sequence Identity: 30% (68 aa)

EVVFIMEYLQGG----ELLEYVT--KKGRL--SELEARQFFRQIVDAIQYCHKENVIHRDLKLENILLS-QSSSSSIIKIIDFGIAG---VGNLNTNKLN
.. ..|||..||    .| .|..  ..|..  || |.. ...||. ...|||....||||||.||||.. .   ....||.|||.|      |   ..  
HIYMVMEYCEGGLYVMDLFDYISTWRHGCFYFSEWECKFYMYQILRGLEYCHSMGIIHRDLKPENILIDNNGHIDACVKICDFGLAKQFDY-NNS-MTTF

VGSLRYMAPEVLL-KQVQSLQKSIDIWSLGVILYTLVVGNLPFNGE------TPSEIIKKITTGSYSFPAQVEGILT-----------------DEIKDL
.|...||||||..  |  .  ...|.||.|.||| .. |..|| |.      .. ..|..|  . ..|. . .                     .| ||.
CGTPWYMAPEVIRGGQYYG--PKVDMWSCGCILYEMLCGRPPFPGHCWHDNHDQMQMICRIMGPPLHFDWPWWCSISYFFFRHWHFHWTFHNWSEECKDF

ITNILIVNPEKRFALKQIRQHEWM
|...| ..|.||   .|| ||.|.
IKWCLCKDPKKRPTAEQILQHPWF
Kinase 10181.AA MARK 153-226 52 5.4e-37 118.59 In-house 77-151 (262) Show / Hide 
Range on Protein: 153-226
Range on HMM: 77-151/262
Sequence Identity: 52% (41 aa)

VVFIMEYLQGGELLEYVTKK--GRLSELEARQFFRQIVDAIQYCHKENVIHRDLKLENILLSQSS--SSSIIKIIDFG
...||||  ||||..|. ..  |||.| |||..||||| |..|||. |..|||.|.||||. .        |||||||
IYLIMEYASGGELYDYIKAHPNGRLHEEEARRIFRQIVSAVNYCHSKNIVHRDIKPENILIDENGNHN---IKIIDFG
Kinase 10181.AA MARK 241-339 43 4.3e-34 108.96 In-house 167-262 (262) Show / Hide 
Range on Protein: 241-339
Range on HMM: 167-262/262
Sequence Identity: 43% (44 aa)

GSLRYMAPEVLLKQVQSLQKSIDIWSLGVILYTLVVGNLPFNGET--PSEIIKKITTGSYSFPAQVEGILTDEIKDLITNILIVNPEKRFALKQIRQHEW
|.. |||||..||.    .| .|||||||.||..|.|..|| | |    |. |||..|.|..|      . .|...||  .| ||||.|  ...| .|.|
GTPPYMAPEIFLKKPYDGPK-VDIWSLGVVLYFMVCGYFPFDGDTQDYKELYKKILRGKYDIPCH----VSKECRNLIQRLLTVNPEERPTIEEIMKHPW

M
|
M
Kinase 10181.AA AGC 99-131 35 7.5e-17 38.65 In-house 1-39 (395) Show / Hide 
Range on Protein: 99-131
Range on HMM: 1-39/395
Sequence Identity: 35% (14 aa)

YEILQTIGEGGFGKVVLAEHK------QTKEKFAIKFVN
.|.| .||.|.|||| |...|      .|.. .|.| ..
FEFLKVIGKGSFGKVYLVRKKDGCHKKDTGKYYAMKVLK
Kinase 10181.AA AMPK 99-147 44 4.8e-15 41.16 In-house 1-49 (254) Show / Hide 
Range on Protein: 99-147
Range on HMM: 1-49/254
Sequence Identity: 44% (22 aa)

YEILQTIGEGGFGKVVLAEHKQTKEKFAIKFVNTSLIGNASDIDMVFRE
| | .||||| |||| ...|..|.|| |||  |   | . ..   . ||
YIIGKTIGEGTFGKVKMGTHILTGEKVAIKILNKQKIKDQDMVERIQRE
Kinase 10181.AA TyrKc 99-339 21 7.8e-14 0.96 SMART 1-280 (280) Show / Hide 
Range on Protein: 99-339
Range on HMM: 1-280/280
Sequence Identity: 21% (65 aa)

YEILQTIGEGGFGKVVLAEHKQTKEKFAIKFVNTSLIGNASDIDMVFREAEGMEVV----------------------------FIMEYLQGGELLEYVT
 . ....||| ||.|.... |   .. |.| .. .       . .  |||. |  .                             .|||  .| |..|  
ITLGKKLGEGAFGEVYKGTWK---IQVAVKMLKEDA------REDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPHGDLKDYLR

KKGR-LSELEARQFFRQIVDAIQYCHKENVIHRDLKLENILLSQSSSSSIIKIIDFGIAGVGNLN--------TNK------LN-VGSLRYMAPEVLLKQ
|... |.  .  .|  || .  .| |. |.|||||   |.|..      ..|| ||| .  .           . .       . .  .| ||||.. . 
KHRPKLCMKDLLSFCWQIACGMEYLHSKNCIHRDLAARNCLVGENH---TVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGKTMLPIRWMAPECINYG

VQSLQKSIDIWSLGVILY-TLVVGNLPFNG-----ETPSEIIKKITTGSYSFPAQV--EGI----LTDEIKDLITNILIVNPEKRFALKQIRQHEWM
. .  || |.|| || ..  .  |  |  |      ...|.|... .| .  . .   . .     .||. ....     .||.|   ..|  || .
KFT-TKS-DVWSFGVCMWEIFTYGQQPYPGMIQQMMSNQEVIEYVKQGYRMPQPPNDYP-MSFVCCPDEMYQIMKQCWHEDPEDRPTFSEI--HECF
Kinase 10181.AA MARK 99-131 51 5e-13 39.09 In-house 1-33 (262) Show / Hide 
Range on Protein: 99-131
Range on HMM: 1-33/262
Sequence Identity: 51% (17 aa)

YEILQTIGEGGFGKVVLAEHKQTKEKFAIKFVN
|..|.|||.|...|| || || |..|.|||...
YKMLKTIGHGSYAKVKLACHKHTGRKVAIKIYE
Kinase 10181.AA Ciliate-E2a 99-131 48 1.3e-12 33.51 In-house 1-33 (275) Show / Hide 
Range on Protein: 99-131
Range on HMM: 1-33/275
Sequence Identity: 48% (16 aa)

YEILQTIGEGGFGKVVLAEHKQTKEKFAIKFVN
|...  ||.| ||.|.||.||||...||.| ..
YKFIKKIGKGNFGSVYLAQHKQTGKQFAMKKFI
Kinase 10181.AA CDPK 99-147 29 5e-12 33.39 In-house 1-51 (271) Show / Hide 
Range on Protein: 99-147
Range on HMM: 1-51/271
Sequence Identity: 29% (15 aa)

YEILQTIGEGGFGKVVLAEHK-QTKEKF-AIKFVNTSLIGNASDIDMVFRE
| |  ..|.|.|| | .. || .|...  |.| .. | . .. .....|.|
YKIKKVLGKGHFGQVRKVKHKQKTNQERVAMKIIPKSRVKDKEQQQQFFNE
Kinase 10181.AA Ciliate-E2 99-129 35 6e-11 33.81 In-house 1-31 (365) Show / Hide 
Range on Protein: 99-129
Range on HMM: 1-31/365
Sequence Identity: 35% (11 aa)

YEILQTIGEGGFGKVVLAEHKQTKEKFAIKF
|.... ||.|.||.| ..........||||.
YKFIKKIGQGNFGSVYKCKVWKVQKQFAIKI
Kinase 10181.AA Pkinase 99-133 37 3e-10 37.33 Pfam 1-35 (293) Show / Hide 
Range on Protein: 99-133
Range on HMM: 1-35/293
Sequence Identity: 37% (13 aa)

YEILQTIGEGGFGKVVLAEHKQTKEKFAIKFVNTS
|.|...||.|.||.| .. || | ...|.| .. .
YHIGRKIGSGSFGCVYKCHHKGTGKIVAVKIIKKR
Kinase 10181.AA Pkinase_Tyr 156-228 36 5e-07 24.42 Pfam 85-158 (270) Show / Hide 
Range on Protein: 156-228
Range on HMM: 85-158/270
Sequence Identity: 36% (28 aa)

IMEYLQGGELLEYVTK----KGRLSELEARQFFRQIVDAIQYCHKENVIHRDLKLENILLSQSSSSSIIKIIDFGIA
.||| ..| ||.|  |    |..|.  .  |. .|| .. .| .  | |||||   |.|..    . ..|| ||| |
VMEYMPHGDLLDYLRKHREDKQPLTMKDLLQMCWQIAKGMEYLESKNCIHRDLAARNCLVTE---NNVVKICDFGLA
Kinase 10181.AA Pkinase_Tyr 99-128 32 0.00939 9.95 Pfam 1-34 (270) Show / Hide 
Range on Protein: 99-128
Range on HMM: 1-34/270
Sequence Identity: 32% (11 aa)

YEILQTIGEGGFGKVVLAEHK----QTKEKFAIK
 ......||| ||.|.... |    .|| . |.|
ITFGKKLGEGAFGEVYKGTWKGDPDNTKIPVAVK