Gene 14487 (Tetrahymena)
14487
Sequence
Protein domains of 14487.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.
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| Domain | Protein name | Domain Name | Range | Identity (%) | Significance | Score | Profile Source | Profile Range (length) | Alignment |
|---|---|---|---|---|---|---|---|---|---|
| Kinase | 14487.AA | MARK | 912-1166 | 52 | 2.1e-169 | 557.69 | In-house | 1-262 (262) | Show / Hide |
Range on Protein: 912-1166 Range on HMM: 1-262/262 Sequence Identity: 52% (137 aa) YLVGKQVGQGAYATVRVALNKIFNKKVAIKIYEKQRIKEPQRKKSVRREIKLLQMLNHQNVIKVYDTIE--TNNH-VNIIMEYIPGTSLHGYLKAQPNRR | ..|. |.|.||.|..|..| ..|||||||||... .|| .|.|.|||.....|.| |.|| ...|| |..| ...||||..|..|..|.||.||.| YKMLKTIGHGSYAKVKLACHKHTGRKVAIKIYEKFKLNDPQWMKNVMREIEIMKKLDHPNIIKLFHVIEQDTEQHQIYLIMEYASGGELYDYIKAHPNGR LTENDAKRIFKQLVSSIEYIHSKQICHRDIKLENILLDENN--NPKLIDFGFSTCIPNDQKYKMFCGTPSYMAPEIVNKREYTGPPADIWALGVLLYALL |.|..|.|||.|.|| ..| ||| |.|||||.||||.|||. | |.||||||.|||..|| ..|||||.||||||..|..|.||..|||.|||.||... LHEEEARRIFRQIVSAVNYCHSKNIVHRDIKPENILIDENGNHNIKIIDFGFSICIPPGQKLNTFCGTPPYMAPEIFLKKPYDGPKVDIWSLGVVLYFMV CGTFPFKGQT--DKELYKKITKGDFLSPDFLSKEARDFIKWVLNTDCDLRPTATEVLSHPWL ||.|||.|.| .|||||||..|.. |...|||.|..|...|..... |||..|...|||. CGYFPFDGDTQDYKELYKKILRGKYDIPCHVSKECRNLIQRLLTVNPEERPTIEEIMKHPWM |
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| Kinase | 14487.AA | CAMKL | 912-1166 | 40 | 2.2e-147 | 473.52 | In-house | 1-297 (297) | Show / Hide |
Range on Protein: 912-1166 Range on HMM: 1-297/297 Sequence Identity: 40% (121 aa) YLVGKQVGQGAYATVRVALN-KIFNKKVAIKIYEKQRIK-EPQRKKS-----------VRREIKLLQMLN---HQNVIKVYDTIETNNH------VNIIM | .||. |.|....|. |.. .. ..||||||..|..|. .|. || .||||....||| |.|.|| |..||| .| ....| YRIGKTLGKGSFGKVKLATHIRTTGEKVAIKIIDKKKIWNDPWMKKNKCGQKHESDMRIRREIQIMKMLNIGKHPNIIKLYEVIETPEHDIETKKIYLVM EYIPGTS--LHGYLKAQPNRR--LTENDAKRIFKQLVSSIEYIHSKQICHRDIKLENILLDENN--NPKLIDFGFST----C-IPNDQKYKMFCGTPSYM ||..| . |. |......|| ..|..|.|.|.|.|| ..|.||. |.|||||.||||||||. | |.||||||. | ....|| |.|||.|.|| EYCSGGEMDLFDYIVKHGHRRGRMPEHEARRYFRQIVSAVNYCHSHGIVHRDIKPENILLDENGNNNIKIIDFGFSNMYRPCIFGPGQKLKTFCGSPPYM APEIVNK--REYTGPPADIWALGVLLYALLCGTFPFKGQTDK-------ELYKKITKGDFLSP--DFLSKEARDFIKWVLNTDCDLRPTATEVLSHPWL ||||... ..| ||..|||..||.|||..||..||...|.. .||.|| .| . | ..| ..||.|.. |... . |||. ....|||. APEIFQGNNKPYDGPKVDIWSCGVILYAMVCGYLPFDDDTYNKQGKDNIYLYWKIMCG-YYPPIWYHVS-DCRDLIRKMLQVNPEKRPTIHQIMNHPWM |
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| Kinase | 14487.AA | CAMK | 917-1166 | 26 | 1.3e-129 | 420.09 | In-house | 1-425 (425) | Show / Hide |
Range on Protein: 917-1166
Range on HMM: 1-425/425
Sequence Identity: 26% (113 aa)
QVGQGAYATVRVALNKIFN------------KKVAIKIYEKQRIKE-------------------------PQRKKSVRREIKLLQM-------LNHQNV
. |.|....|. . .| . .||||||..|...|. |. .|.|||||..... |.| |.
TLGRGSFGKVKLCIHKNTTGKERVHHIYTNGQKVAIKIIDKKKLKDKQNQDYSNCYKIDKSKCKHRYCWRRPKDRKNVRREIEIMKKLQGIGNKLDHPNI
IKVYDTIE------------TNNH--------VNIIM---EYIPGT----SLHGYLKAQPN-------------RRLTENDAKRIFKQLVSSIEYIHSKQ
|| |...| | .. . ..| ||..| | |...... .|.|| .|.|.|.|..| ..|.||.
IKLYEVYEDPHYFKNTNDYET-SKQVFTKDKHMYMVMEIMEYCSGGELFDDLFDYIVEHGCYGEEFDQFDIVERGRFTEREARRYFRQICSAVHYCHSHN
ICHRDIKLENILLDEN-----------------NNPKLIDFGFSTCIPN------------------------DQKYKMFCGTPSYMA-PEIVNK-----
|.|||.|.||||||.| || |.|||||.. .. .||.| |||||.||| ||..|.
IVHRDLKPENILLDDNNDDSDPVEHDEIFDWNNNNIKIIDFGFANKFDPGENNFMCSDYKGGEMHNQWTTPTEGQKMKTFCGTPEYMAAPEVLNGKGHCN
--------REYTGPPADIWALGVLLYALLCGTFPFKGQ-------------TDKELYKKITKGDFL-SPDF-----------------------LSKEAR
..| ||..|.|..||.||..|||..|| | .|.||..||.||.. |.. .|.|..
MQNATDEEKPYYGPKCDMWSCGVILYIMLCGYPPFYGDCDNEICEDEWIGMNDYELFEKIMKGKYDFPPPYFSPISCNYGPEWWDDISDEFHHFVSQECK
DFIKWVLNTDCDLRPTATEVLSHPWL
|.|.. |..| . |.|....|.|||.
DLIRKMLQVDPEKRMTIEQCLNHPWM
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| Kinase | 14487.AA | Pkinase | 912-1166 | 31 | 1.7e-107 | 368.24 | Pfam | 1-293 (293) | Show / Hide |
Range on Protein: 912-1166 Range on HMM: 1-293/293 Sequence Identity: 31% (94 aa) YLVGKQVGQGAYATVRVALNKIFNKKVAIKIYEKQRIKEPQRKKSVR-REIKLLQMLNHQNVIKVYDTIETNNHVNIIMEYIPGT----SLHGYLKAQPN | .|...|.|....|. . .| .|.||.|| .|...|. ... .| .||.....||| |... ||. |...|. ..||| .|. .|. |.... . YHIGRKIGSGSFGCVYKCHHKGTGKIVAVKIIKKRHEKSWKDQTHRRLSEIQIMKRLNHPNIVRLYDWFEDKDHIYMVMEYCEGGLYVMDLFDYISTWRH RRL--TENDAKRIFKQLVSSIEYIHSKQICHRDIKLENILLDENNNP----KLIDFGFSTC--IPNDQKYKMFCGTPSYMAPEIVNKREYTGPPADIWAL ... .|...|....|... .||.||. |.|||.|.||||.|.|... |..|||.. . . |.. .. ||||| |||||......| ||..|.|.. GCFYFSEWECKFYMYQILRGLEYCHSMGIIHRDLKPENILIDNNGHIDACVKICDFGLAKQFDY-NNS-MTTFCGTPWYMAPEVIRGGQYYGPKVDMWSC GVLLYALLCGTFPFKGQ------TDKELYKKITKGDFLSPDFLS---------------------KEARDFIKWVLNTDCDLRPTATEVLSHPWL |..|| .||| .||.|. ........| .... .. . . .|..||||| |. |. ||||...| |||. GCILYEMLCGRPPFPGHCWHDNHDQMQMICRIMGPPLHFDWPWWCSISYFFFRHWHFHWTFHNWSEECKDFIKWCLCKDPKKRPTAEQILQHPWF |
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| Kinase | 14487.AA | AMPK | 912-1166 | 41 | 8e-104 | 309.1 | In-house | 1-254 (254) | Show / Hide |
Range on Protein: 912-1166 Range on HMM: 1-254/254 Sequence Identity: 41% (106 aa) YLVGKQVGQGAYATVRVALNKIFNKKVAIKIYEKQRIKEPQRKKSVRREIKLLQMLNHQNVIKVYDTI-ETNNHVNIIMEYIPGTSLHGYLKAQPNRRLT |..|| | |.. | .. .. ..|||||| .||.||. . .....|||..|....|...|. |. | ||. ..|||..| | | .||. YIIGKTIGEGTFGKVKMGTHILTGEKVAIKILNKQKIKDQDMVERIQREIHILKLFRHPHIIQLYEVIIETPTDIFMVMEYVSGGELFDYIVKH--GRLQ ENDAKRIFKQLVSSIEYIHSKQICHRDIKLENILLDENNNPKLIDFGFSTCIPNDQKYKMFCGTPSYMAPEIVNKREYTGPPADIWALGVLLYALLCGTF | .|.| |.| .| .||.| | ||| |.||.|||.|.| |. ||| | .. | || | | |||.. . | || ||| || |||.|||. EREACRFFQQIISGVEYCHRHMIVHRDLKPENLLLDHNKNIKIVDFGLSNMMKDGEFLKTACGSPCYAAPEMISGKLYCGPEVDIWSCGVILYAMLCGYL PFKGQTDKELYKKITKGDFLSPDFLSKEARDFIKWVLNTDCDLRPTATEVLSHPWL || . .|||||..|.. |.|||.||.| || |..| | | .. |||. PFDDENTPTLYKKIKNGEYYIPKFLSPEAKDLIKHMLQVDPMKRITIHDIRNHPWF |
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| Kinase | 14487.AA | NuaK | 912-1166 | 39 | 2.3e-102 | 269.95 | In-house | 1-252 (252) | Show / Hide |
Range on Protein: 912-1166 Range on HMM: 1-252/252 Sequence Identity: 39% (101 aa) YLVGKQVGQGAYATVRVALNKIFNKKVAIKIYEKQRIKEPQRKKSVRREIKLLQMLNHQNVIKVYDTIETNNHVNIIMEYIPGTSLHGYLKAQPNRRLTE | . |. |.| | |. | .. . ..|||| |..|...| .||||... ||| ..|..| | . . |.||| | | |. ..|.| YEFQKTLGKGTYGKVKLATEHSTGREVAIKSIKKCKIEDEQDMVHIRREIEIMSSLNHPHIIHIYEVFENKDKIVIVMEYASGGELYDYISEC--KSLPE NDAKRIFKQLVSSIEYIHSKQICHRDIKLENILLDENNNPKLIDFGFSTCIPNDQKYKMFCGTPSYMAPEIVNKREYTGPPADIWALGVLLYALLCGTFP ..|...| | || . | | .||||| ||||||||.|.| | ||| | ... . ||| | | ||||| . |.|| | |.||||||.. || | REARHFFRQIVSAVHYCHKHRICHRDLKLENILLDQNCNAKIADFGLSNYYHDQKFLHTFCGSPLYASPEIVNGQPYHGPEVDCWSLGVLLYTMVYGTMP FKGQTDKELYKKITKGDFLSPDFLSKEARDFIKWVLNTDCDLRPTATEVLSHPWL | |. |.| | |..|.. | | .|. | | | . . | | .. .|.|. FDGHDFKHLVKQISQGAYYEPCKPS-DACMLIRWMLMVNPRRRATIYDICHHWWV |
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| Kinase | 14487.AA | S_TKc | 912-1166 | 34 | 1.1e-101 | 345.06 | SMART | 1-231 (231) | Show / Hide |
Range on Protein: 912-1166 Range on HMM: 1-231/231 Sequence Identity: 34% (93 aa) YLVGKQVGQGAYATVRVALNKIFNKKVAIKIYEKQRIKEPQRKKSVRREIKLLQMLNHQNVIKVYDTIETNNHVNIIMEYIPG--TSLHGYLKAQPNRR- | .....|.||...|. . .| ...||||| ...||||..|.. .| |..| ||.... .|. ..|||..| .|. |.| .. .. YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK----------EHIRREIQILKK-HHPNIVKLYDVFQD-DHLYMVMEYCDGDLGDLFDYIKKRGRHGL ---LTENDAKRIFKQLVSSIEYIHSKQICHRDIKLENILLDENNNPKLIDFGFSTCIPNDQKYKMFCGTPSYMAPEIVNKREYTGPPADIWALGVLLYAL ..| .|.....|... .||.||..|.|||.| ||||||| . |..|||... . . ||||| |||||.. |.....|.|..|..|| . RFPFPE-HARFYMYQICCALEYCHSHGIIHRDLKPENILLDE--HIKICDFGLARQL------TTFCGTPWYMAPEVL---GYGKCKCDWWSCGCILYEM LCGTFPFKGQTDKELYKKITKGDFLSPDFLSKEARDFIKWVLNTDCDLRPTATEVLS-------HPWL ||| || ......||| |.||.|||. |. | . |||| |.| |||. LCGYPPFP--QMQMMFKKIG----------SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF |
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| Kinase | 14487.AA | Aur | 912-1166 | 39 | 4.2e-97 | 256.64 | In-house | 1-257 (257) | Show / Hide |
Range on Protein: 912-1166 Range on HMM: 1-257/257 Sequence Identity: 39% (102 aa) YLVGKQVGQGAYATVRVALNKIFNKKVAIKIYEKQRIKEPQRKKSVRREIKLLQMLNHQNVIKVYDTIETNNHVNIIMEYIPGTSLHGYLKAQPNRRLTE .||. |.|.. |. | .| ....|.|. .|. ||. . .. .|||||. ||| |..| |. . .... .|.|| || .| .|. |||.|..| FEIGKPLGKGKFGNVYLARHKKTHFIFALKVMFKEQIKKYCMEHQLRREIKIQSHLNHPNILKMYGYFHDDQRIYLILEYAPGGELYKELQKQPNKRFDE NDAKRIFKQLVSSIEYIHSKQICHRDIKLENILLD-ENNNPKLIDFGFSTCIPNDQKYKMFCGTPSYMAPEIVNKREYTGPPADIWALGVLLYALLCGTF . | ....|. . ..| |||.| ||||| |||||| .|.| |. ||| |. || .. . |||| ||.||.|. ... . |||.||||.| |. | QRAAKYMYQICNALDYCHSKNIIHRDIKPENILLDQCNGNIKICDFGWSVHCPNNNRRMTFCGTLDYMPPEMVEGQMH-DHKVDIWCLGVLCYELCHGCP PFKG-QTDKELYKKIT-KGDFLSPDFLSKEARDFIKWVLNTDCDLRPTATEVLSHPWL ||.. ....| |..| |.|. |...||||.|.|. .| | | | ....||| PFESNENHDETYDRIKNKVDIQFPSHISKEAKDLISKILQHDPKQRMTLDQIMNHPWI |
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| Kinase | 14487.AA | QIK | 912-1166 | 35 | 1.2e-86 | 294.18 | In-house | 1-272 (272) | Show / Hide |
Range on Protein: 912-1166
Range on HMM: 1-272/272
Sequence Identity: 35% (98 aa)
YLVGKQVGQGAYATVRVALNKIFNKKVAIKIYEKQRIKEPQRKKSVRREIKLLQMLNHQNVIKVYDTIETNNHVNIIMEYIPGTSLHGYLKAQPN-----
| ... .| | .|.|..| ..| .|||||| | .. | .| . ||.... ||.| ..|| |. .|| . |..|| .. . || ..
YDIERTIGKGNFAVVKLARHRITKTKVAIKIIDKSQLDEENLQK-CYREVQIMKMLYHPHIIKLYQVMETDDMMYIVTEYCSNGEMFDYLCKHGRKGVKM
-------------RRLTENDAKRIFKQLVSSIEYIHSKQICHRDIKLENILLDENNNPKLIDFGFSTCIPNDQKYKMFCGTPSYMAPEIVNKREYTGPPA
..||.|.|.|.|..| ..| |...| |||.| ||||||.| | |..||||| ..| . .||.| | |||. .||.|| .
VNSPDIGDQVLMGVPMAENEARRWFWQICSAVHYCHKRNIVHRDLKAENILLDNNMNIKIADFGFSNWFKQGQLLMTWCGSPPYAAPEMFEGKEYDGPKV
DIWALGVLLYALLCGTFPFKGQTDKELYKKITKGDFLSPDFLSKEARDFIKWVLNTDCDLRPTATEVLSHPWL
||| .||.||.| || .|| |.|...| ... | | | |.|.. ..|. | | . | | .. |.|.
DIWSMGVVLYVLVCGALPFDGKTLQNLRQRVLSGKFRIPFFMSQDCEHLIRHMLVVDPEHRYTIMQICQHRWM
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| Kinase | 14487.AA | Ciliate-E2 | 912-1166 | 26 | 2.8e-86 | 292.94 | In-house | 1-365 (365) | Show / Hide |
Range on Protein: 912-1166 Range on HMM: 1-365/365 Sequence Identity: 26% (99 aa) YLVGKQVGQGAYATVRVA---LNKIFN--------------------KKVAIKIYEKQRIKEPQRKKSVRREIK----------LLQMLNHQNVIKVYDT | . |. |||....|. . ... |..|.||..|. |.. ..... |||. .|. ||| |.|| |.. YKFIKKIGQGNFGSVYKCKVWKVQKQFAIKIIDQKQQRQQMQEKVKIKIYAMKIMKKNQIEQIKQEIHIMREINCFYKKINEKNILEQLNHPNIIKMYEC IE--TNNHVNIIMEYIPGTSLHGYLKAQPNRR---------LTENDAKRIFKQLVS---------------SIEYIHSKQ-ICHRDIKLENILLDENNNP . ..|.. ..|||. | .| |.| .. | .||. .|.|.||... .||.||| |.|||||.||||. . FQEKDDNNIYLVMEYCQGGDLFDYIKNNKKKRNHEIEKDKYFTEKEIKYIMKQILQGFKTKAEFYIACIILALEYLHSKNNIIHRDIKPENILF-----I KLIDFGFSTCIPND--------------------------------QKYKMFCGTPSYMAPEIVNKREYTG--------PPADIWALGVLLYALLCGTFP |.||||.|. . .| . .. .|||| ||||||.|. .|.. .|||.|||.|| .|.| .| KIIDFGLSKKYDDDNQNRTHKQQCKWYMFKNDTSRTPGYMDQIIQQNMFNTICGTPGYMAPEILNGKKYDNQQKQKGYDYKCDIWSLGVILYEMLFGKPP FKGQTDKELYKKITKGDFLSPDF------------------LSKEARDFIKW----VLNTDCDLRPT-ATEVLSHPWL | ...| .... | . .|.|. |.|| |. | . |.| . ..| |||. F--------QQQIKQCKIDFPCPEWQKDTQCIQCKWKSWKKWSQECKDLIKKFGKRMLQKDPEKRITGWEQILNHPWF |
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| Kinase | 14487.AA | Ciliate-E2-Unclassified | 912-1166 | 26 | 4.3e-80 | 272.38 | In-house | 1-352 (352) | Show / Hide |
Range on Protein: 912-1166
Range on HMM: 1-352/352
Sequence Identity: 26% (95 aa)
YLVGKQVGQGAYATVRVALNKIFNKKVAIKIYEKQRIKEPQRKKSV---------RREIK-------------LLQMLNHQNVIKVYDTIETNNHVNIIM
| ..|| |||....|. . .| ... |.|. |..|. . .... ..| .|....| ...| ... .. ... |.|
YKIIKQIGQGGFGKVYKCQHKKQKQYYAMKYMKKIQIYKQKQIMNKDEIMNEMKEMNNKKKYHQRKYNKIMQQILLNHPHPFIVKMFYCFQDKQNIYIVM
EYIPGTSLHGYLKAQPN---------------RRLTENDAK-----RIFKQLVSSIEYIHSKQ-ICHRDIKLENILLDENN---NPKLIDFGFST-----
||..| .|. |.| ... ...||. || ..|.|... .||.|.|. |.|||||.||||.|.|. ..|.||||.|
EYCEGGDLWQYIKKRKKQKQKGNDLFHNMKQRKIFTEQQAKYKKAKFYFAQILQGLEYLHHKNNIIHRDIKPENILFDNNGKNYYIKIIDFGISKKYQQN
-----------CIPNDQKYKMFCGTPSYM----APEIVNKREYTGP---PADIWALGVLLYALLCGTFPFKGQTDKE----------------LYKKITK
|. .|... |||||.|| |||. . .| .. .|||.|||.||..| |..||....... ||..| .
NNCDTNQQQKMQIWKQQMMWTFCGTPNYMPQYTAPEVLQGQNYDHSKAYKCDIWSLGVILYEMLFGYYPFYDNNCEQHQQLITQWINNAYRKQLYQNIKQ
GDFLSPDFL--------SKEARDFIK----WVLNTDCDLRPTATEVLSHPWL
... | | |.|| |||. |. ... |.|. ..| |||.
KNIQFPKFPWQQIPKHWSPEAKDFINDLLQKMLKKNPNKRITFEQILNHPWF
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| Kinase | 14487.AA | CAMK-Unique | 912-1166 | 25 | 9.3e-80 | 262.93 | In-house | 1-363 (363) | Show / Hide |
Range on Protein: 912-1166
Range on HMM: 1-363/363
Sequence Identity: 25% (92 aa)
YLVGKQVGQGAYATVRVALNKIFNKKVAIKIYEKQRIKEPQRKK-----------------SVRREIKLLQMLNHQNVIKVYDT----IETNN-------
| .. .|.|.. |. .... || |.|. .||. .. .| . .||. ...|..|.| ||.||. .. .
YKMHRIIGHGNFGHVYECMDRETGKKWACKMVKKQTHGNKKQKQQRNFDLRYKITEKRRDMKLKREHQIWKMVDHPNIIKLYDWNNPIFCDRKYPLCDLI
--------HVNIIMEYIPGTSLHGYLKA------------------QPNRRLTE--NDAKRIFKQLVSSIEYIHSKQICHRDIKLENILLDEN-------
. |.|||..| | .. . . .....| .|. .|. .|.| ..| ||..| |||.|||||.. ..
IKTPRALPYMYIVMEYCQGGDLFDWIQKWDEFYFNFIIKFDFNILKRCQGHFSERCWDTCFIMQCLLSAVAYMHSQDIVHRDLKLENIMVCYSFKDNNHH
---------NNPKLIDFGFSTCIPNDQKYK---MFCGTPSYMAP--------------EIVNKREYTGPPA---DIWALGVLLYALLCGTFPFKGQTDK-
.. ||.||| .. . . ... .||||.|||| |..| . | .. |||.|||..| .||| || .....
RDFPYDWSNWHIKLCDFGLCCHYNHNKMCHMMQTMCGTPCYMAPEIVFCKNYQEMTRDEVINMQCYDQQCSPASDIWSLGVIMYYMLCGCPPFDCECEDR
-------ELYKKITKGDF--------LSPDFLSKEARDFIKWVLNTDCDLRPTATEVLSHPWL
|....|.|||. .||. |.|| ||.| ...| | | .| | |.|.|.
DYENHDKEIFECICKGDYCNFDWKMWHGPDYISQEAKDFVKCCMTVDPDHRWSAKELLEHQWI
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| Kinase | 14487.AA | TyrKc | 912-1166 | 24 | 2.2e-17 | 58.3 | SMART | 1-280 (280) | Show / Hide |
Range on Protein: 912-1166 Range on HMM: 1-280/280 Sequence Identity: 24% (71 aa) YLVGKQVGQGAYATVRVALNKIFNKKVAIKIYEKQRIKEPQRKKSVRREIKLLQML--NHQNVIKVYDTIETN-------NHVNIIMEYIPGTSLHGYLK ||. | ||. .|. . | .||.| . .. .||.... .| .|.|... | . . . |.||| |. .|. ||. ITLGKKLGEGAFGEVYKGTWK---IQVAVKMLKEDA------REDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPHGDLKDYLR AQPNRRLTENDAKRIFKQLVSSIEYIHSKQICHRDIKLENILLDENNNPKLIDFGFSTCIPND------QKYKMFC---GTPS-----YMAPEIVNKREY . .. |. | . | . ||.|||.. |||. |.|..||. | ||| | | .| ..|.. |. . |||| |.... KHRPK-LCMKDLLSFCWQIACGMEYLHSKNCIHRDLAARNCLVGENHTVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGKTMLPIRWMAPECINYGKF TGPPADIWALGVLLYALL-CGTFPFKG-----QTDKELYKKITKGDFLSPDFL---------SKEARDFIKWVLNTDCDLRPTATEVLSHPWL | . |.|. ||... .. | | | ...|..... .|. . . ..| . .|. . | . ||| .|. | . T-TKSDVWSFGVCMWEIFTYGQQPYPGMIQQMMSNQEVIEYVKQGYRMPQPPNDYPMSFVCCPDEMYQIMKQCWHEDPEDRPTFSEI--HECF |
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| Kinase | 14487.AA | Pkinase_Tyr | 912-1127 | 29 | 6.3e-13 | 44.4 | Pfam | 1-232 (270) | Show / Hide |
Range on Protein: 912-1127 Range on HMM: 1-232/270 Sequence Identity: 29% (70 aa) YLVGKQVGQGAYATVRVALNK----IFNKKVAIKIYEKQRIKEPQ-RKKSVRREIKLLQML-NHQNVIKVYDTIE-TNNH--VNIIMEYIPGTSLHGYLK ||. |.||. .|. . | . .||.|. |. ..| ... ||.|.. | .|.|... | . . . |.||| |. .|. ||. ITFGKKLGEGAFGEVYKGTWKGDPDNTKIPVAVKML-KEGAMHEQNCREDFMREAKIMKQLGHHPNIVRLYGVCTDQGEPNQIYIVMEYMPHGDLLDYLR AQ--PNRRLTENDAKRIFKQLVSSIEYIHSKQICHRDIKLENILLDENNNPKLIDFGFSTCIPNDQKY-KMFCGTPS---YMAPEIVNKREYTGPPADIW .. ....|| | . | . || .||.. |||. |.|..||| | ||| . | || | .. |.. |||| | ...| |.| KHREDKQPLTMKDLLQMCWQIAKGMEYLESKNCIHRDLAARNCLVTENNVVKICDFGLARDIYNDDYYYRKRGGGKLPIKWMAPECINYGKFT-TKSDVW ALGVLLYALLC-GTFP-FKGQTDKELYKKI-TKG . |||.. .. | | ..| .. |.|..| .| SFGVLMWEIFTYGEQPTYPGMSNEEVYEYIYEDG |
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| Kinase | 14487.AA | APH | 1032-1063 | 19 | 0.000451 | 14.77 | Pfam | 171-206 (248) | Show / Hide |
Range on Protein: 1032-1063 Range on HMM: 171-206/248 Sequence Identity: 19% (7 aa) QICHRDIKLENILLD--ENNNPK--LIDFGFSTCIP ..||.| .. |...| ..... .||..... . CWCHGDFHPGNVMWDPRPDGGRVTGVIDWDDACWGD |
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| RIO | 14487.AA | RIO | 881-1084 | 15 | 0.000536 | -99.05 | SMART | 1-253 (253) | Show / Hide |
Range on Protein: 881-1084 Range on HMM: 1-253/253 Sequence Identity: 15% (39 aa) EEKERKIIQEYFCEQQFQDDNIDKTQKFKEEYLVG--KQVGQGAYATVRVALN---KIFNKKVAIKIY------EKQR---IKEPQRKK----------- . ..... .| | . . . . |. ... . .. ... | | | .|.. . ...|.||| .| . |. .| | DKEDYATYEEVF--DPRTRMTLYKMVNRGYIEEINNHGCISTGKEANVYHAMGGDFDKNGNECAVKIYRTSTTEFKRMWRYIQGDFRFKHGYHHINWRKM ---SVRREIKLLQMLNHQNVIKVYDTIETNNHVNIIMEYIPGTSLHGYLKAQPNRRLTENDAK-RIFKQLVSSIEYIHSKQ-ICHRDIKLENILLD---- ....| . ||.. .... |. ..|| ..||.| . .. . .. . | | | ...|...... . . | | |.|.. VRLWAEKEFRNLQRMYEA-GVPCPKPIAWRRHV-LVMEFIGDDGWPAPRLKDVEWEEWEMDFKWEYYWQIMEYMRKMYHECHLVHADLSEYNMLYHDLED -ENNNPKLIDFGFS----------------TCIPND-QKYKMFCGT-PSYMAPEIVN ... . .||.. | ..| |. .... | . .. .|. ENDCKVWIIDWSQSVECDHPMWLEFLERDIWNIINFFRRKGVDCDDIYREIFERITG |
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| Kinase | 14487.AA | APH | 914-1030 | 13 | 2.958376 | 1.75 | Pfam | 1-112 (248) | Show / Hide |
Range on Protein: 914-1030 Range on HMM: 1-112/248 Sequence Identity: 13% (17 aa) VGKQVGQGAYA-TVRVALNKIFNKKVAIKIYEKQRIKEPQRKKSVRREIKLLQMLNHQNV---I-KVYD---TIETNNHVNIIMEYIPGTSLHGYLKAQP ..... |. |... .. ... ..|... . . ...||...|. | . . . .|.. . | . .. .||..||..|. WWRPISGGWSNRTYYRTTDDR--PRYVLRRYPPP-----WWAEELHREHRWLRHLAAHGIPVPVPRVLWGCTDDEFHGWPWYLMEWLPGEDLWRW----- NRR-LTENDAKRIFKQLVSSIEYIHS . |..... .....|. . .|. --HALHCAQRPALLEALARFLARLHQ |
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