20819

Species: Tetrahymena
Alias: TTHERM_00151610, 3700.m00213, 20819, PreTt20819, 522, 12.m00493
External Links: Tetrahymena Genome Database (TGD)
Annotation:

Classification

Group: CAMK
Family: CAMKL
Subfamily: MARK

Sequence

Name Sequence Type Origin Length Description Download
20819.AA Protein None 447 None Fasta, JSON
20819.kin_dom Protein Kinase Domain None 255 None Fasta, JSON
20819.NA RNA None 1344 None Fasta, JSON

Protein domain

Protein domains of 20819.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Kinase 20819.AA MARK 173-427 53 5.1e-168 553.12 In-house 1-262 (262) Show / Hide
Range on Protein: 173-427
Range on HMM: 1-262/262
Sequence Identity: 53% (139 aa)

YTLGPVIGTGSYATVKLGVDKVNNIKVAVKLYEKFKLFDPQKKKNVQREIQILQKLDHSHCIKLFKTID--TPKH-INLVMEYVGSSSLHSYLKLHTGRK
| .. .||.||||.|||...|  ..|||.| ||||||.|||..|||.|||.|..|||| ..||||..|.  |..| |.|.|||... .|..|.| |....
YKMLKTIGHGSYAKVKLACHKHTGRKVAIKIYEKFKLNDPQWMKNVMREIEIMKKLDHPNIIKLFHVIEQDTEQHQIYLIMEYASGGELYDYIKAHPNGR

LPENEAKRIFKQLILGLEYLHSKNVVHRDIKLENILLDKQN--NVKIIDFGFSIIIPPEKKLSIFCGTPSYMAPEIVAKKEYYGQPVDIWAAGILLYVML
|.|.||.|||.|.. ...|.||||.||||||.||||.|...  |.|||||||||.|||..||..|||||.||||||. ||.|.|..||||. |..||.|.
LHEEEARRIFRQIVSAVNYCHSKNIVHRDIKPENILIDENGNHNIKIIDFGFSICIPPGQKLNTFCGTPPYMAPEIFLKKPYDGPKVDIWSLGVVLYFMV

CGTFPFR--GIDDKTLFKEIQRGEAKFPPHVSTGAKYLIQKILNTNNNERINATSILKDTWL
||.|||.  ..|.|.|.|.|.||. ..|.|||.... |||..|..| .||. .. |.|. |.
CGYFPFDGDTQDYKELYKKILRGKYDIPCHVSKECRNLIQRLLTVNPEERPTIEEIMKHPWM

Kinase 20819.AA CAMKL 173-427 39 1.1e-146 471.28 In-house 1-297 (297) Show / Hide
Range on Protein: 173-427
Range on HMM: 1-297/297
Sequence Identity: 39% (117 aa)

YTLGPVIGTGSYATVKLGVD-KVNNIKVAVKLYEKFKLF-DPQKKKN-----------VQREIQILQKLD---HSHCIKLFKTIDTPKH------INLVM
|..|...|.||...|||... . ...|||.| ..|.|.  ||..|||           ..|||||...|.   | . |||. .|.||.|      |.|||
YRIGKTLGKGSFGKVKLATHIRTTGEKVAIKIIDKKKIWNDPWMKKNKCGQKHESDMRIRREIQIMKMLNIGKHPNIIKLYEVIETPEHDIETKKIYLVM

EYVGSSS--LHSYLKLHTGRK--LPENEAKRIFKQLILGLEYLHSKNVVHRDIKLENILLDKQN--NVKIIDFGFSII-----IPPEKKLSIFCGTPSYM
||... .  |. |.. | .|.  .||.||.|.|.|.. ...|.||...||||||.||||||...  |.||||||||..     ..|..||..|||.|.||
EYCSGGEMDLFDYIVKHGHRRGRMPEHEARRYFRQIVSAVNYCHSHGIVHRDIKPENILLDENGNNNIKIIDFGFSNMYRPCIFGPGQKLKTFCGSPPYM

APEIVAK--KEYYGQPVDIWAAGILLYVMLCGTFPFR-------GIDDKTLFKEIQRGEAKFPP---HVSTGAKYLIQKILNTNNNERINATSILKDTWL
||||...  |.|.|..||||..|..||.|.||..||.       | |.. ........  ..||   |||  .. ||.|.|..| ..|...  |... |.
APEIFQGNNKPYDGPKVDIWSCGVILYAMVCGYLPFDDDTYNKQGKDNI-YLYWKIMCG-YYPPIWYHVS-DCRDLIRKMLQVNPEKRPTIHQIMNHPWM





Kinase 20819.AA CAMK 178-427 26 6.5e-125 404.67 In-house 1-425 (425) Show / Hide
Range on Protein: 178-427
Range on HMM: 1-425/425
Sequence Identity: 26% (114 aa)

VIGTGSYATVKLGVDKVNN------------IKVAVKLYEKFKLFD-------------------------PQKKKNVQREIQILQK-------LDHSHC
..|.||...|||...| ..             |||.| ..| || |                         |...|||.|||.|..|       ||| . 
TLGRGSFGKVKLCIHKNTTGKERVHHIYTNGQKVAIKIIDKKKLKDKQNQDYSNCYKIDKSKCKHRYCWRRPKDRKNVRREIEIMKKLQGIGNKLDHPNI

IKLFKTID------------TPKH--------INLVM---EYVGSS----SLHSYLKLHTG-------------RKLPENEAKRIFKQLILGLEYLHSKN
|||. ...            | ..        . .||   ||.        | .|.. |..             ....| ||.|.|.|.. ...|.||.|
IKLYEVYEDPHYFKNTNDYET-SKQVFTKDKHMYMVMEIMEYCSGGELFDDLFDYIVEHGCYGEEFDQFDIVERGRFTEREARRYFRQICSAVHYCHSHN

VVHRDIKLENILLDKQ-----------------NNVKIIDFGFSIIIPP------------------------EKKLSIFCGTPSYMA-PEIVAK-----
.||||.|.||||||.                  ||.|||||||.....|                         .|.. |||||.||| ||.. .     
IVHRDLKPENILLDDNNDDSDPVEHDEIFDWNNNNIKIIDFGFANKFDPGENNFMCSDYKGGEMHNQWTTPTEGQKMKTFCGTPEYMAAPEVLNGKGHCN

--------KEYYGQPVDIWAAGILLYVMLCGTFPFRGI-------------DDKTLFKEIQRGEAKFPPH------------------------VSTGAK
        |.|||...|.|..|..||.||||..||.|              .|. ||. |..|.  |||.                        ||. .|
MQNATDEEKPYYGPKCDMWSCGVILYIMLCGYPPFYGDCDNEICEDEWIGMNDYELFEKIMKGKYDFPPPYFSPISCNYGPEWWDDISDEFHHFVSQECK

YLIQKILNTNNNERINATSILKDTWL
 ||.|.|... ..|.... .|.. |.
DLIRKMLQVDPEKRMTIEQCLNHPWM

Kinase 20819.AA AMPK 173-427 41 2.5e-101 301.57 In-house 1-254 (254) Show / Hide
Range on Protein: 173-427
Range on HMM: 1-254/254
Sequence Identity: 41% (107 aa)

YTLGPVIGTGSYATVKLGVDKVNNIKVAVKLYEKFKLFDPQKKKNVQREIQILQKLDHSHCIKLFKTI-DTPKHINLVMEYVGSSSLHSYLKLHTGRKLP
| .|  ||.|..  ||.|. .  . |||.|  .| |. | . .. .||||.||... | | |.|.  | .||. | .|||||    | .|   |  ..|.
YIIGKTIGEGTFGKVKMGTHILTGEKVAIKILNKQKIKDQDMVERIQREIHILKLFRHPHIIQLYEVIIETPTDIFMVMEYVSGGELFDYIVKH--GRLQ

ENEAKRIFKQLILGLEYLHSKNVVHRDIKLENILLDKQNNVKIIDFGFSIIIPPEKKLSIFCGTPSYMAPEIVAKKEYYGQPVDIWAAGILLYVMLCGTF
| ||.| |.| | |.||.|  ..|||| |.||.|||...|.|| ||| | .    ..|.  || | | |||... | | |  ||||  |. ||.||||. 
EREACRFFQQIISGVEYCHRHMIVHRDLKPENLLLDHNKNIKIVDFGLSNMMKDGEFLKTACGSPCYAAPEMISGKLYCGPEVDIWSCGVILYAMLCGYL

PFRGIDDKTLFKEIQRGEAKFPPHVSTGAKYLIQKILNTNNNERINATSILKDTWL
||   .  ||.| |  || . | ..|. ||.||...|... ..||.   | .. |.
PFDDENTPTLYKKIKNGEYYIPKFLSPEAKDLIKHMLQVDPMKRITIHDIRNHPWF

Kinase 20819.AA S_TKc 173-427 32 5.3e-95 322.85 SMART 1-231 (231) Show / Hide
Range on Protein: 173-427
Range on HMM: 1-231/231
Sequence Identity: 32% (87 aa)

YTLGPVIGTGSYATVKLGVDKVNNIKVAVKLYEKFKLFDPQKKKNVQREIQILQKLDHSHCIKLFKTIDTPKHINLVMEYVGS--SSLHSYLKLHTGRK-
|... .|| |....|.....|  . .||.|             ....||||||.| .| . .||. .... .|. .||||..    .|..|.| . ... 
YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK----------EHIRREIQILKK-HHPNIVKLYDVFQD-DHLYMVMEYCDGDLGDLFDYIKKRGRHGL

---LPENEAKRIFKQLILGLEYLHSKNVVHRDIKLENILLDKQNNVKIIDFGFSIIIPPEKKLSIFCGTPSYMAPEIVAKKEYYGQ-PVDIWAAGILLYV
   .|| .|.....|....|||.||....|||.| ||||||.  ..||.|||.. ..      . ||||| |||||..     ||  ..|.|. |..|| 
RFPFPE-HARFYMYQICCALEYCHSHGIIHRDLKPENILLDE--HIKICDFGLARQL------TTFCGTPWYMAPEVL----GYGKCKCDWWSCGCILYE

MLCGTFPFRGIDDKTLFKEIQRGEAKFPPHVSTGAKYLIQKILNTNNNERINATSILK-------DTWL
||||  ||.  .....|| |           |  || .|.|.|. . ..|. |  .|.       . |.
MLCGYPPFP--QMQMMFKKIG----------SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF

Kinase 20819.AA Pkinase 173-427 30 1.4e-93 322.02 Pfam 1-293 (293) Show / Hide
Range on Protein: 173-427
Range on HMM: 1-293/293
Sequence Identity: 30% (89 aa)

YTLGPVIGTGSYATVKLGVDKVNNIKVAVKLYEKFKLFDPQKKKNVQ-REIQILQKLDHSHCIKLFKTIDTPKHINLVMEYVGSS----SLHSYLKLHTG
|..| .|| ||...|.....| ....||||  .| .  . ... ..  .||||...|.| . ..|. .  ...|| .||||..      .|..|.. . .
YHIGRKIGSGSFGCVYKCHHKGTGKIVAVKIIKKRHEKSWKDQTHRRLSEIQIMKRLNHPNIVRLYDWFEDKDHIYMVMEYCEGGLYVMDLFDYISTWRH

RKL--PENEAKRIFKQLILGLEYLHSKNVVHRDIKLENILLDKQNNV----KIIDFGFSII--IPPEKKLSIFCGTPSYMAPEIVAKKEYYGQPVDIWAA
...  .|.|.|....|.. ||||.||....|||.|.||||.|.....    ||.|||..    . .   .. ||||| |||||.. . .|||..||.|..
GCFYFSEWECKFYMYQILRGLEYCHSMGIIHRDLKPENILIDNNGHIDACVKICDFGLAKQFDY-NNS-MTTFCGTPWYMAPEVIRGGQYYGPKVDMWSC

GILLYVMLCGTFPFRGI------DDKTLFKEIQRGEAKFPPHVS---------------------TGAKYLIQKILNTNNNERINATSILKDTWL
|..|| |||| .||.|       |.. ....| ... .|.   .                       .| .| ..|. . ..|..|. ||.. |.
GCILYEMLCGRPPFPGHCWHDNHDQMQMICRIMGPPLHFDWPWWCSISYFFFRHWHFHWTFHNWSEECKDFIKWCLCKDPKKRPTAEQILQHPWF

Kinase 20819.AA TSSK 173-427 31 2e-79 260.34 In-house 1-289 (289) Show / Hide
Range on Protein: 173-427
Range on HMM: 1-289/289
Sequence Identity: 31% (92 aa)

YTLGPVIGTGSYATVKLGVDKVNNIK----------------VAVKLYEKFKLFDPQKKKNVQREIQILQK-LDHSHCIKLFKTIDTPK-HINLVMEYVG
|..| .||.||||.|.....| ...|                ||.|   . |  .  ..|   |||||. | |.|.. |... ...|   .| .||||  
YNVGKKIGHGSYAKVYCAYSKKHKCKHNPRLRDDLRIKRHTHVAIKIIDRKKAPTDYLNKFLPREIQIMRKTLKHPNIIQFYEMFETCQGKIYMVMEYAE

SSSLHSYLKLH---TGRK-LPENEAKRIFKQLILGLEYLHSKNVVHRDIKLENILLDKQNNVKIIDFGFSIIIPPEK------KLSIFCGTPSYMAPEIV
.  | .| . .   .. . |.| .|.. |.|.. ...|.||.||||||.|.|||||||..|.|..||||. . |. .      ... |||  .| ||||.
HGDLLEYIQRRTQERCCGALHEEQARKWFRQMVSAVKYCHSHNVVHRDLKCENILLDKHWNIKLTDFGFARYWPRDDPGRCCHLSKTFCGSYAYAAPEIL

AKKEYYGQPVDIWAAGILLYVMLCGTFPFRG--IDDKTLFKEIQRGEAKFP----PHVSTGAKYLIQKILNTNNNERINATSILKDTWL
  ..| .  .|.|. |. ||.|.||. ||     . ... ...|  ...||    ...|. .| || ..|  . ..|.... |... |.
RGIPYDPKWYDVWSMGVILYIMVCGCMPFDDDKSNIHKMLWQQQEHKVCFPKPHSCWISQECKDLIRHMLQPHPCNRPHINEICHHCWM

Kinase 20819.AA Ciliate-E2 173-427 25 3.9e-79 269.22 In-house 1-365 (365) Show / Hide
Range on Protein: 173-427
Range on HMM: 1-365/365
Sequence Identity: 25% (97 aa)

YTLGPVIGTGSYATVKLGVD-----------------------KVNNIKVAVKLYEKFKLFDPQKKKNVQREIQ----------ILQKLDHSHCIKLFKT
| .  .||.|....|... .                       ||.. ..|.| ..| ...   ..... |||.          ||..|.| . ||.. .
YKFIKKIGQGNFGSVYKCKVWKVQKQFAIKIIDQKQQRQQMQEKVKIKIYAMKIMKKNQIEQIKQEIHIMREINCFYKKINEKNILEQLNHPNIIKMYEC

ID--TPKHINLVMEYVGSSSLHSYLKLH----------TGRKLPENEAKRIFKQLIL---------------GLEYLHSKN-VVHRDIKLENILLDKQNN
    . ..| |||||.   .| .|.| .             .. |.|.|.|.||..                .|||||||| ..|||||.||||.     
FQEKDDNNIYLVMEYCQGGDLFDYIKNNKKKRNHEIEKD-KYFTEKEIKYIMKQILQGFKTKAEFYIACIILALEYLHSKNNIIHRDIKPENILF-----

VKIIDFGFSIIIPPE------KKLSI--------------------------FCGTPSYMAPEIVAKKEY--------YGQPVDIWAAGILLYVMLCGTF
.||||||.| .. ..      |...                           .|||| ||||||. .|.|        |.  .|||..|..|| ||.| .
IKIIDFGLSKKYDDDNQNRTHKQQCKWYMFKNDTSRTPGYMDQIIQQNMFNTICGTPGYMAPEILNGKKYDNQQKQKGYDYKCDIWSLGVILYEMLFGKP

PFRGIDDKTLFKEIQRGEAKFP------------------PHVSTGAKYLIQK----ILNTNNNERIN-ATSILKDTWL
||        ...|. .. .||                   ..|  .| ||.|    .|. . ..||. .  ||.  |.
PF--------QQQIKQCKIDFPCPEWQKDTQCIQCKWKSWKKWSQECKDLIKKFGKRMLQKDPEKRITGWEQILNHPWF

Kinase 20819.AA Ciliate-E2-Unclassified 173-427 26 2.2e-78 266.73 In-house 1-352 (352) Show / Hide
Range on Protein: 173-427
Range on HMM: 1-352/352
Sequence Identity: 26% (94 aa)

YTLGPVIGTGSYATVKLGVDKVNNIKVAVKLYEKFKLFDPQKKKNV--------QREIQ--------------ILQKLDHSHCIKLFKTIDTPKHINLVM
|... .||.|....|.. ..| .. . | |   |.. .. ....|.        . ...              ||. ..| . .|.| .  . ..| .||
YKIIKQIGQGGFGKVYKCQHKKQKQYYAMKYMKKIQIYKQKQIMNKDEIMNEMKEMNNKKKYHQRKYNKIMQQILLNHPHPFIVKMFYCFQDKQNIYIVM

EYVGSSSLHSYLKL---------------HTGRKLPENEAK-----RIFKQLILGLEYLHSKN-VVHRDIKLENILLDKQN---NVKIIDFGFSII----
||.   .|. |.|                .......|..||     ..|.|...||||||.|| ..|||||.||||.|...   ..||||||.|.     
EYCEGGDLWQYIKKRKKQKQKGNDLFHNMKQRKIFTEQQAKYKKAKFYFAQILQGLEYLHHKNNIIHRDIKPENILFDNNGKNYYIKIIDFGISKKYQQN

------------IPPEKKLSIFCGTPSYM----APEIVAKKEYYG---QPVDIWAAGILLYVMLCGTFPFRGIDDKT----------------LFKEIQR
            |....... |||||.||    |||.  ...|..     .|||. |..|| || |..|| . ...                 |...|. 
NNCDTNQQQKMQIWKQQMMWTFCGTPNYMPQYTAPEVLQGQNYDHSKAYKCDIWSLGVILYEMLFGYYPFYDNNCEQHQQLITQWINNAYRKQLYQNIKQ

GEAKFPP--------HVSTGAKYLIQ----KILNTNNNERINATSILKDTWL
.. .||.        |.|  || .|.    |.|. | |.||..  ||.  |.
KNIQFPKFPWQQIPKHWSPEAKDFINDLLQKMLKKNPNKRITFEQILNHPWF

Kinase 20819.AA QIK 173-427 35 1.8e-77 263.66 In-house 1-272 (272) Show / Hide
Range on Protein: 173-427
Range on HMM: 1-272/272
Sequence Identity: 35% (98 aa)

YTLGPVIGTGSYATVKLGVDKVNNIKVAVKLYEKFKLFDPQKKKNVQREIQILQKLDHSHCIKLFKTIDTPKHINLVMEYVGSSSLHSYLKLHTGR----
|...  || | .|.|||.  ..   |||.|   | .| | .  . . ||.||.  |.| | |||.  . | . . .|.||  .  .  ||  | ||    
YDIERTIGKGNFAVVKLARHRITKTKVAIKIIDKSQL-DEENLQKCYREVQIMKMLYHPHIIKLYQVMETDDMMYIVTEYCSNGEMFDYLCKH-GRKGVK

---------------KLPENEAKRIFKQLILGLEYLHSKNVVHRDIKLENILLDKQNNVKIIDFGFSIIIPPEKKLSIFCGTPSYMAPEIVAKKEYYGQP
                ..||||.|.|.|.... .|.|..|.||||.| ||||||.. |.||.|||||    ... |. .||.| | |||.   ||| |  
MVNSPDIGDQVLMGVPMAENEARRWFWQICSAVHYCHKRNIVHRDLKAENILLDNNMNIKIADFGFSNWFKQGQLLMTWCGSPPYAAPEMFEGKEYDGPK

VDIWAAGILLYVMLCGTFPFRGIDDKTLFKEIQRGEAKFPPHVSTGAKYLIQKILNTNNNERINATSILKDTWL
||||  |..|||. || .|| |  ...| . .  |  . |. .|..   || . |  . . |..   |..  |.
VDIWSMGVVLYVLVCGALPFDGKTLQNLRQRVLSGKFRIPFFMSQDCEHLIRHMLVVDPEHRYTIMQICQHRWM

Kinase 20819.AA ULK 173-427 27 3.2e-69 236.29 In-house 1-329 (329) Show / Hide
Range on Protein: 173-427
Range on HMM: 1-329/329
Sequence Identity: 27% (91 aa)

YTLGPVIGTGSYATVKLGVDKVN----NIKVAVKLYEKFK-LFDPQK------KKNVQREIQILQKLD--------HSHCIKLFKTIDTP--KHINLVME
| |  ..| ||...|  | .| .    |.|||.|  .|.|   ...       .. ...||.|..||.        | ...||..   |.  ..| ..||
YCLNHCLGKGSFGKVYKGRNKKTKDYVNEKVACKMIDKQKMNQKNNEQEGQYMWQLLKNEIKIMKKLKSPNRHKNHHPNIVKLYDWFETSNHNNIYIIME

YVGSSSLHSYLKLH--------TGRKLPENEAKRIFKQLILGLEYLHSKNVVHRDIKLENILLDKQNN------------VKIIDFGFSIIIPPE-----
|     | .|.| .        ....|.|.||. .|||.. |. .||..|..|||||..|||... .             .|| ||||.  .  .     
YCNGGDLEQYIKKNKKLPEDTEEKKRLSEQEAIQFFKQILNGFKELHKHNIIHRDIKPQNILIHNGQPKTDSKKVHPNGVLKIADFGFAKHVDNDNMEQQ

-KKLSI----FCGTPSYMAPEIVA----KKEYYGQPVDIWAAGILLYVMLCGTFPFRGIDDKTLF-----KE----------IQRGEAKFP-----PHVS
  .       .|||| ||||.|.     .|.||   .|||  |...| || |  ||..    ...     |.          |.    .||     |..|
MMMTCVNEKRLCGTPLYMAPQILQGQGEQKPYYDYKCDIWSLGCIFYEMLYGKPPFYAW-FNDQYLQIIQKLINNPPPWPQQIKKQPLQFPKDGNDPQIS

TGAKYLIQKILNTNNNERINATSILKDTWL
   | ||.. |  . ..||. . ...  |.
PECKDLIRRMLQYDEKDRISWEELFNHPWF

Kinase 20819.AA CAMK1 272-427 35 6.2e-61 175.84 In-house 107-276 (276) Show / Hide
Range on Protein: 272-427
Range on HMM: 107-276/276
Sequence Identity: 35% (61 aa)

ENEAKRIFKQLILGLEYLHSKNVVHRDIKLENILL-DKQNN--VK--IIDFGFSIIIPPEK-KLSIFCGTPSYMAPEIVAKK--EYYGQPVDIWAAGILL
|..| .| ||..  .||.|||..||||.| ||.|. || ..  .|  |.||| | |. ..  ...  ||||.|.|||... |  . |....|.| .|. .
EKDARHIMKQILSAVEYMHSKGIVHRDLKPENLLYYDKDEDSKIKRSIADFGLSKIFDHDENLMKTACGTPGYVAPEVLECKKDKPYDKACDMWSIGVIT

YVMLCGTFPFRGID-DKTLFKEIQRGEAKFPPH----VSTG-AKYLIQKILNTNNNERINATSILKDTWL
|..|||  || . . |..||. | ..|  ||      .| . || .| . |. . ..|.... .|.. |.
YILLCGYPPFYDENVDNELFEKIKKCEYEFPSPWWDNISDQEAKDFIKHMLEVDPKKRYTCEQCLNHPWI

Kinase 20819.AA CAMK1 173-253 30 3.1e-23 64.34 In-house 1-90 (276) Show / Hide
Range on Protein: 173-253
Range on HMM: 1-90/276
Sequence Identity: 30% (28 aa)

YTLGPVIGTGSYATVKLGVDKVN---NIKVAVKLYEKFKLFDPQKK----KNVQREIQILQK---LDHSHCIKLFKTIDTPKHINLVMEYV
| .| .||.|. ..|.|...| .   . ..|.|  .| | |  .|.    .....||.|..|   .|| ..||..   ....|. ||||.|
YEFGKEIGRGAFSEVYLCTHKETQTNGKQYAIKCIDK-KKFMKKKDMQKQEALENEIEIMKKVSKIDHPNIIKFYEWYESDNHFYLVMELV

Kinase 20819.AA Pkinase_Tyr 173-318 31 1.1e-18 63.87 Pfam 1-156 (270) Show / Hide
Range on Protein: 173-318
Range on HMM: 1-156/270
Sequence Identity: 31% (50 aa)

YTLGPVIGTGSYATVKLGVDK----VNNIKVAVKLYEKFKLFDPQK--KKNVQREIQILQKL-DHSHCIKL--FKT-IDTPKHINLVMEYVGSSSLHSYL
 |.| ..| |.. .|..|. |     ..|.||||        ...   ..   ||..|. .| .| . ..|    |  . |..| .||||.   .|..||
ITFGKKLGEGAFGEVYKGTWKGDPDNTKIPVAVKMLKE--GAMHEQNCREDFMREAKIMKQLGHHPNIVRLYGVCTDQGEPNQIYIVMEYMPHGDLLDYL

KLH--TGRKLPENEAKRIFKQLILGLEYLHSKNVVHRDIKLENILLDKQNNVKIIDFG
. |   ...|.  .   .  |   |.|||.||| .|||.   |.|....| ||| |||
RKHREDKQPLTMKDLLQMCWQIAKGMEYLESKNCIHRDLAARNCLVTENNVVKICDFG

Kinase 20819.AA TyrKc 173-425 23 7.2e-17 50.07 SMART 1-280 (280) Show / Hide
Range on Protein: 173-425
Range on HMM: 1-280/280
Sequence Identity: 23% (67 aa)

YTLGPVIGTGSYATVKLGVDKVNNIKVAVKLYEKFKLFDPQKKKNVQREIQILQKL--DHSHCIKLFKTIDTP-------KHINLVMEYVGSSSLHSYLK
 ||| ..| | . .| .|. |   |.||||   . .      ..   ||..|. ||  .| . ..|.  . ..       . . .||||.   .|..||.
ITLGKKLGEGAFGEVYKGTWK---IQVAVKMLKEDA------REDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPHGDLKDYLR

LHTGRKLPENEAKRIFKQLILGLEYLHSKNVVHRDIKLENILLDKQNNVKIIDFGFSIIIPPE-----KKLSIFC----GTPS-----YMAPEIVAKKEY
 | .. |.  .   .  |   | |||||||..|||.   |.|..... ||| ||| |  |  .      |  .      |. .      ||||   ....
KHRPK-LCMKDLLSFCWQIACGMEYLHSKNCIHRDLAARNCLVGENHTVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGKTMLPIRWMAPECINYGKF

YGQPVDIWAAGILLY-VMLCGTFPFRG-----IDDKTLFKEIQRGEAKFPPHV---------STGAKYLIQKILNTNNNERINATSILKDT
  .  |.|. |.... ..  |  |  |     .... ... ...|.   .|.          ..    ....  . . ..| . . | .. 
TTK-SDVWSFGVCMWEIFTYGQQPYPGMIQQMMSNQEVIEYVKQGYRMPQPPNDYPMSFVCCPDEMYQIMKQCWHEDPEDRPTFSEIHECF