Gene 26669 (Tetrahymena)

26669

Species: Tetrahymena
Alias: 26669, 3702.m00089, PreTt26669, 11.m00366, 496, TTHERM_00143620
External Links: Tetrahymena Genome Database (TGD)
Annotation:

Classification

Group: CAMK
Family: CAMKL
Subfamily: MARK

Sequence

Name Sequence Type Origin Length Description Download
26669.AA Protein None 902 None Fasta, JSON
26669.kin_dom Protein Kinase Domain None 219 None Fasta, JSON
26669.NA RNA None 2709 None Fasta, JSON

Protein domain

Protein domains of 26669.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Kinase 26669.AA MARK 714-859 55 7.6e-96 313.76 In-house 113-262 (262) Show / Hide 
Range on Protein: 714-859
Range on HMM: 113-262/262
Sequence Identity: 55% (83 aa)

IISGIQYMHNKNVCHRDIKLENILIDDDL--NLKIIDFGFAVVSPIERKLDSFCGTPSYMSPEIVLKKEYIGQYVDIWTCGIVLYILICGKFPFKGAD--
|.|...|.|.||..|||||.||||||..   | |||||||..  | ..||..|||||.||.|||.|||.| |. ||||..|.|||...||.|||.|..  
IVSAVNYCHSKNIVHRDIKPENILIDENGNHNIKIIDFGFSICIPPGQKLNTFCGTPPYMAPEIFLKKPYDGPKVDIWSLGVVLYFMVCGYFPFDGDTQD

EKELYRKISKHQYEIPSFVERGARSLIQRLLSFNPEDRPSCLEILKDKWL
.||||.|| ...|.||..| ...|.|||||| .|||.||.. ||.|..|.
YKELYKKILRGKYDIPCHVSKECRNLIQRLLTVNPEERPTIEEIMKHPWM
Kinase 26669.AA CAMKL 714-859 40 1.6e-80 256.65 In-house 136-297 (297) Show / Hide 
Range on Protein: 714-859
Range on HMM: 136-297/297
Sequence Identity: 40% (66 aa)

IISGIQYMHNKNVCHRDIKLENILIDDDL--NLKIIDFGFA-----VVSPIERKLDSFCGTPSYMSPEIVLK--KEYIGQYVDIWTCGIVLYILICGKFP
|.|...|.|.....|||||.||||.|..   |.|||||||.     .. . ..||. |||.|.||.|||...  |.|.|. |||| ||..|| ..||..|
IVSAVNYCHSHGIVHRDIKPENILLDENGNNNIKIIDFGFSNMYRPCIFGPGQKLKTFCGSPPYMAPEIFQGNNKPYDGPKVDIWSCGVILYAMVCGYLP

FKGA--------DEKELYRKISKHQYEIP--SFVERGARSLIQRLLSFNPEDRPSCLEILKDKWL
|...        .  .||.|| .. |..|  ..|   .|.||...|  |||.||.. .|....|.
FDDDTYNKQGKDNI-YLYWKIMCG-YYPPIWYHVS-DCRDLIRKMLQVNPEKRPTIHQIMNHPWM
Kinase 26669.AA CAMK 714-859 26 4.1e-75 241.31 In-house 188-425 (425) Show / Hide 
Range on Protein: 714-859
Range on HMM: 188-425/425
Sequence Identity: 26% (64 aa)

IISGIQYMHNKNVCHRDIKLENILIDDD-----------------LNLKIIDFGFAVVSPI------------------------ERKLDSFCGTPSYMS
|.|...|.|..|..|||.|.||||.||.                  |.|||||||| . .                           |.  |||||.||.
ICSAVHYCHSHNIVHRDLKPENILLDDNNDDSDPVEHDEIFDWNNNNIKIIDFGFANKFDPGENNFMCSDYKGGEMHNQWTTPTEGQKMKTFCGTPEYMA

-PEIVLK-------------KEYIGQYVDIWTCGIVLYILICGKFPFKGA-------------DEKELYRKISKHQYE-IPSFVER--------------
 ||....             |.|.|. .|.| ||..|||. ||..|| |              ...||..|| | .|. .|...                
APEVLNGKGHCNMQNATDEEKPYYGPKCDMWSCGVILYIMLCGYPPFYGDCDNEICEDEWIGMNDYELFEKIMKGKYDFPPPYFSPISCNYGPEWWDDIS

---------GARSLIQRLLSFNPEDRPSCLEILKDKWL
          ...||...|  .||.|... ..|...|.
DEFHHFVSQECKDLIRKMLQVDPEKRMTIEQCLNHPWM
S_TKc 26669.AA S_TKc 641-859 28 9.4e-66 225.67 SMART 1-231 (231) Show / Hide 
Range on Protein: 641-859
Range on HMM: 1-231/231
Sequence Identity: 28% (75 aa)

FQILDTLGKGSYAQVKLAIDKRTNQKIAIKIYEKFKLTDPNKFKNVRREINILSKMTHENIIRLYHVID----------------TVSS-----------
..||...|||....|.....|.|... ||||            ...||||.||.|  |.||..|| |..                .. .           
YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK----------EHIRREIQILKK-HHPNIVKLYDVFQDDHLYMVMEYCDGDLGDLFDYIKKRGRHGLR

-------------IISGIQYMHNKNVCHRDIKLENILIDDDLNLKIIDFGFAVVSPIERKLDSFCGTPSYMSPEIVLKKEYIGQ-YVDIWTCGIVLYILI
             |.....|.|.....|||.| ||||.|.  ..||.|||.| .       ..||||| ||.||..      |   .|.| ||..||...
FPFPEHARFYMYQICCALEYCHSHGIIHRDLKPENILLDE--HIKICDFGLARQL------TTFCGTPWYMAPEVL----GYGKCKCDWWSCGCILYEML

CGKFPFKGADEKELYRKISKHQYEIPSFVERGARSLIQRLLSFNPEDRPSCLEILK-------DKWL
||. ||   .......||            . |...|...| ..||.||.. |.|.       . |.
CGYPPFP--QMQMMFKKIG----------SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF
Kinase 26669.AA AGC 714-859 21 2e-65 167.14 In-house 162-395 (395) Show / Hide 
Range on Protein: 714-859
Range on HMM: 162-395/395
Sequence Identity: 21% (52 aa)

IISGIQYMHN-KNVCHRD-IKLENILIDDDLNLKIIDFGFAVVSPIER---------------------------------------------------K
|.....|.|. ... ||| .|.||||.|.| ..|. |||.. . . ..                                                   .
IVLALEYLHSHMGIIHRDYLKPENILLDEDGHIKLTDFGLCKEGMNDGEKGQQSQSNMKFHWHNKKYQKSNMDTNKCNPNNWQRNNMSQEDDTTRKKRDR

LDSFCG--TPSYMSPEIVLKKEYIGQYVDIWT--CGIVLYILICGKFPFKGA----------DEKELYRKIS------KHQYEIP----------SFVER
  .|||  || ||.|||.      |. .|.|.   |...| ...|. || |           ...|.. ||       ... ..|          ...  
TWTFCGPCTPEYMAPEIL-----YGKACDWWSFGLGCLMYEMLTGYPPFYGDNPQENRHPFRNPMEMFQKIMNGRYFINWKVKFPFPEDPQFPEDRWFSP

GARSLIQRLLSFNPEDRPSCL----------EILKDKWL
 |..||..||  .||.|. |.          || . .| 
EAKDLIKKLLCKDPEKRLGCGGNDFGDKGAEEIKNHPWF
Kinase 26669.AA AMPK 714-859 39 4e-61 180.22 In-house 109-254 (254) Show / Hide 
Range on Protein: 714-859
Range on HMM: 109-254/254
Sequence Identity: 39% (58 aa)

IISGIQYMHNKNVCHRDIKLENILIDDDLNLKIIDFGFAVVSPIERKLDSFCGTPSYMSPEIVLKKEYIGQYVDIWTCGIVLYILICGKFPFKGADEKEL
||||. |.|. .. ||| |.||.|.|.. |.|| |||   .     .|   || | | .||..  | | | .|||| ||..|| ..||. ||   .  .|
IISGVEYCHRHMIVHRDLKPENLLLDHNKNIKIVDFGLSNMMKDGEFLKTACGSPCYAAPEMISGKLYCGPEVDIWSCGVILYAMLCGYLPFDDENTPTL

YRKISKHQYEIPSFVERGARSLIQRLLSFNPEDRPSCLEILKDKWL
|.|| . .|.||.|... |..||...|  .|. | .  .| ...|.
YKKIKNGEYYIPKFLSPEAKDLIKHMLQVDPMKRITIHDIRNHPWF
Kinase 26669.AA Pkinase 711-859 29 9.3e-58 202.99 Pfam 114-293 (293) Show / Hide 
Range on Protein: 711-859
Range on HMM: 114-293/293
Sequence Identity: 29% (53 aa)

VSSIISGIQYMHNKNVCHRDIKLENILIDDDLNL----KIIDFGFAVV--SPIERKLDSFCGTPSYMSPEIVLKKEYIGQYVDIWTCGIVLYILICGKFP
.  |..|..|.|.....|||.|.||||||.. ..    ||.|||.| .      . ...||||| ||.||.... .|.|. ||.| ||..||...||..|
MYQILRGLEYCHSMGIIHRDLKPENILIDNNGHIDACVKICDFGLAKQFDY-NNS-MTTFCGTPWYMAPEVIRGGQYYGPKVDMWSCGCILYEMLCGRPP

FKGA------DEKELYRKISKHQYEIPSFVE---------------------RGARSLIQRLLSFNPEDRPSCLEILKDKWL
|.|.      |.......| . ... ... .                     . ....| ..| ..|..||.. .||...|.
FPGHCWHDNHDQMQMICRIMGPPLHFDWPWWCSISYFFFRHWHFHWTFHNWSEECKDFIKWCLCKDPKKRPTAEQILQHPWF
Kinase 26669.AA Aur 714-859 37 9.4e-55 142.58 In-house 110-257 (257) Show / Hide 
Range on Protein: 714-859
Range on HMM: 110-257/257
Sequence Identity: 37% (56 aa)

IISGIQYMHNKNVCHRDIKLENILIDD-DLNLKIIDFGFAVVSPIERKLDSFCGTPSYMSPEIVLKKEYIGQYVDIWTCGIVLYILICGKFPFKG-ADEK
|.... |.| ||. ||||| ||||.|. . |.|| ||| .|. | . .   ||||  ||.||.|  ... .. ||||  |. .| |. |. ||..  . .
ICNALDYCHSKNIIHRDIKPENILLDQCNGNIKICDFGWSVHCPNNNRRMTFCGTLDYMPPEMVEGQMH-DHKVDIWCLGVLCYELCHGCPPFESNENHD

ELYRKIS-KHQYEIPSFVERGARSLIQRLLSFNPEDRPSCLEILKDKWL
| |..|. | ....||..  .|. ||...|  .|. | .  .|.. .| 
ETYDRIKNKVDIQFPSHISKEAKDLISKILQHDPKQRMTLDQIMNHPWI
Kinase 26669.AA NuaK 714-859 41 4.3e-53 137.63 In-house 108-252 (252) Show / Hide 
Range on Protein: 714-859
Range on HMM: 108-252/252
Sequence Identity: 41% (60 aa)

IISGIQYMHNKNVCHRDIKLENILIDDDLNLKIIDFGFAVVSPIERKLDSFCGTPSYMSPEIVLKKEYIGQYVDIWTCGIVLYILICGKFPFKGADEKEL
|.| . | |  ..|||| |||||| |.. | || |||   .   .. |  ||| | | |||||  . | |  || |  |..||... |  || | | |.|
IVSAVHYCHKHRICHRDLKLENILLDQNCNAKIADFGLSNYYHDQKFLHTFCGSPLYASPEIVNGQPYHGPEVDCWSLGVLLYTMVYGTMPFDGHDFKHL

YRKISKHQYEIPSFVERGARSLIQRLLSFNPEDRPSCLEILKDKWL
 . ||. .|  |    . |. ||  .|. ||. | .  .| .  |.
VKQISQGAYYEPCKPSD-ACMLIRWMLMVNPRRRATIYDICHHWWV
Kinase 26669.AA CAMK1 709-859 33 2.5e-51 147.42 In-house 112-276 (276) Show / Hide 
Range on Protein: 709-859
Range on HMM: 112-276/276
Sequence Identity: 33% (56 aa)

DTVSSIISGIQYMHNKNVCHRDIKLENIL---IDDDLNLK--IIDFGFAVVSPIER-KLDSFCGTPSYMSPEIVLK---KEYIGQYVDIWTCGIVLYILI
...  |.| ..||| |...|||.| ||.|   .|.|  .|  |.||| .     .  ..   ||||.|. ||..     | | .. .|.| .|...||| 
HIMKQILSAVEYMHSKGIVHRDLKPENLLYYDKDEDSKIKRSIADFGLSKIFDHDENLMKTACGTPGYVAPEVLECKKDKPY-DKACDMWSIGVITYILL

CGKFPFKGAD-EKELYRKISKHQYEIPSF-----VERGARSLIQRLLSFNPEDRPSCLEILKDKWL
||  || . . ..||..||.| .|| ||.     .. .|  .|  .|  .|. |..| ..|...|.
CGYPPFYDENVDNELFEKIKKCEYEFPSPWWDNISDQEAKDFIKHMLEVDPKKRYTCEQCLNHPWI
Kinase 26669.AA Ciliate-E2 711-859 24 1.9e-49 167.87 In-house 166-365 (365) Show / Hide 
Range on Protein: 711-859
Range on HMM: 166-365/365
Sequence Identity: 24% (53 aa)

VSSIISGIQYMHNKN-VCHRDIKLENILIDDDLNLKIIDFGFAVVSPIE--------------------------------RKLDSFCGTPSYMSPEIVL
. .||....|.|.|| ..|||||.||||.     .||||||..    ..                                   ...|||| ||.|||. 
IACIILALEYLHSKNNIIHRDIKPENILF-----IKIIDFGLSKKYDDDNQNRTHKQQCKWYMFKNDTSRTPGYMDQIIQQNMFNTICGTPGYMAPEILN

KKEY--------IGQYVDIWTCGIVLYILICGKFPFKGADEKELYRKISKHQYEIPSF------------------VERGARSLIQR----LLSFNPEDR
.|.|         .  .||| .|..||....||.||        ...| . ....|..                  ..  .  ||..    .|  .|| |
GKKYDNQQKQKGYDYKCDIWSLGVILYEMLFGKPPF--------QQQIKQCKIDFPCPEWQKDTQCIQCKWKSWKKWSQECKDLIKKFGKRMLQKDPEKR

PS-CLEILKDKWL
..   .||. .|.
ITGWEQILNHPWF
Kinase 26669.AA QIK 714-859 39 1.6e-48 167.48 In-house 127-272 (272) Show / Hide 
Range on Protein: 714-859
Range on HMM: 127-272/272
Sequence Identity: 39% (58 aa)

IISGIQYMHNKNVCHRDIKLENILIDDDLNLKIIDFGFAVVSPIERKLDSFCGTPSYMSPEIVLKKEYIGQYVDIWTCGIVLYILICGKFPFKGADEKEL
|.|...| |..|. |||.| ||||.| ..| ||.||||   .  .  | ..||.| |  ||. . ||| |  ||||  |.|||.|.||..|| |   ..|
ICSAVHYCHKRNIVHRDLKAENILLDNNMNIKIADFGFSNWFKQGQLLMTWCGSPPYAAPEMFEGKEYDGPKVDIWSMGVVLYVLVCGALPFDGKTLQNL

YRKISKHQYEIPSFVERGARSLIQRLLSFNPEDRPSCLEILKDKWL
 ...   .. || |.  .  .|| . |  .|| | .   |.. .|.
RQRVLSGKFRIPFFMSQDCEHLIRHMLVVDPEHRYTIMQICQHRWM
Kinase 26669.AA MARK 641-712 58 4.3e-43 138.82 In-house 1-74 (262) Show / Hide 
Range on Protein: 641-712
Range on HMM: 1-74/262
Sequence Identity: 58% (43 aa)

FQILDTLGKGSYAQVKLAIDKRTNQKIAIKIYEKFKLTDPNKFKNVRREINILSKMTHENIIRLYHVID--TVS
. .| |.|.||||.||||..|.|..| ||||||||||.||...|||.|||.|..|. |.|||.|.|||.  | .
YKMLKTIGHGSYAKVKLACHKHTGRKVAIKIYEKFKLNDPQWMKNVMREIEIMKKLDHPNIIKLFHVIEQDTEQ
Kinase 26669.AA CAMKL 641-710 43 3.3e-38 119.45 In-house 1-86 (297) Show / Hide 
Range on Protein: 641-710
Range on HMM: 1-86/297
Sequence Identity: 43% (37 aa)

FQILDTLGKGSYAQVKLAID-KRTNQKIAIKIYEKFKLT-DPNKFKN-----------VRREINILSKMT---HENIIRLYHVIDT
..|..||||||...||||.. . |..| ||||..|.|.. ||.. ||           .||||.|....    |.|||.||.||.|
YRIGKTLGKGSFGKVKLATHIRTTGEKVAIKIIDKKKIWNDPWMKKNKCGQKHESDMRIRREIQIMKMLNIGKHPNIIKLYEVIET
Kinase 26669.AA CAMK 646-712 32 2.7e-29 90.95 In-house 1-122 (425) Show / Hide 
Range on Protein: 646-712
Range on HMM: 1-122/425
Sequence Identity: 32% (40 aa)

TLGKGSYAQVKLAIDKRTN------------QKIAIKIYEKFKLTD-------------------------PNKFKNVRREINILSK-------MTHENI
|||.||...|||.|.|.|.            || ||||..| ||.|                         |.. |||||||.|..|       . |.||
TLGRGSFGKVKLCIHKNTTGKERVHHIYTNGQKVAIKIIDKKKLKDKQNQDYSNCYKIDKSKCKHRYCWRRPKDRKNVRREIEIMKKLQGIGNKLDHPNI

IRLYHVID------------TVS
|.||.|..            | |
IKLYEVYEDPHYFKNTNDYET-S
Kinase 26669.AA AMPK 641-710 39 2.3e-27 78.32 In-house 1-71 (254) Show / Hide 
Range on Protein: 641-710
Range on HMM: 1-71/254
Sequence Identity: 39% (28 aa)

FQILDTLGKGSYAQVKLAIDKRTNQKIAIKIYEKFKLTDPNKFKNVRREINILSKMTHENIIRLYHVI-DT
..| .|.|.|..  ||... ..|..| |||| .| |..|    . ..||| || ...| .||.|| || .|
YIIGKTIGEGTFGKVKMGTHILTGEKVAIKILNKQKIKDQDMVERIQREIHILKLFRHPHIIQLYEVIIET
Kinase 26669.AA NuaK 641-707 41 5.5e-26 64.85 In-house 1-67 (252) Show / Hide 
Range on Protein: 641-707
Range on HMM: 1-67/252
Sequence Identity: 41% (28 aa)

FQILDTLGKGSYAQVKLAIDKRTNQKIAIKIYEKFKLTDPNKFKNVRREINILSKMTHENIIRLYHV
.... ||||| |  ||||... | ...|||   | |  |..    .|||| |.| . | .||  | |
YEFQKTLGKGTYGKVKLATEHSTGREVAIKSIKKCKIEDEQDMVHIRREIEIMSSLNHPHIIHIYEV
Kinase 26669.AA Aur 641-706 36 1e-25 64.35 In-house 1-66 (257) Show / Hide 
Range on Protein: 641-706
Range on HMM: 1-66/257
Sequence Identity: 36% (24 aa)

FQILDTLGKGSYAQVKLAIDKRTNQKIAIKIYEKFKLTDPNKFKNVRREINILSKMTHENIIRLYH
|.|   ||||.. .|.||..| |....|.|. .|  .   .  ...||||.| |.. |.||...|.
FEIGKPLGKGKFGNVYLARHKKTHFIFALKVMFKEQIKKYCMEHQLRREIKIQSHLNHPNILKMYG
Kinase 26669.AA AGC 641-706 22 7.8e-21 49.18 In-house 1-98 (395) Show / Hide 
Range on Protein: 641-706
Range on HMM: 1-98/395
Sequence Identity: 22% (22 aa)

FQILDTLGKGSYAQVKLAIDKR-----TNQKI-AIKIYEKFK---LTDPNKFKNVRRE------------INILSKMT----------HENIIR-LYH
|..| ..||||. .| |. .|      ...|. |.|. .| .   ... |. ... .|             |||.|.           | .|.. |..
FEFLKVIGKGSFGKVYLVRKKDGCHKKDTGKYYAMKVLKKKHKIVIKKKNMVEHTMTEHWKQDQGYVWEERNILEKCNHTHNHPIKSHHPFIVKILHY
Kinase 26669.AA CAMK1 641-705 28 1.3e-19 53.58 In-house 1-74 (276) Show / Hide 
Range on Protein: 641-705
Range on HMM: 1-74/276
Sequence Identity: 28% (21 aa)

FQILDTLGKGSYAQVKLAIDKRT---NQKIAIKIYEKFKLTDPNKF----KNVRREINILSKM---THENIIRLY
... ...|.|. ..|.|...|.|   ....|||. .| |    .|     .....||.|. |     |.||| .|
YEFGKEIGRGAFSEVYLCTHKETQTNGKQYAIKCIDK-KKFMKKKDMQKQEALENEIEIMKKVSKIDHPNIIKFY
Kinase 26669.AA Pkinase 641-707 33 3.5e-18 65.36 Pfam 1-68 (293) Show / Hide 
Range on Protein: 641-707
Range on HMM: 1-68/293
Sequence Identity: 33% (23 aa)

FQILDTLGKGSYAQVKLAIDKRTNQKIAIKIYEKFKLTDPNKFKNVRR--EINILSKMTHENIIRLYHV
..|. ..|.||...|.....| |... |.|| .|   ....| .. ||  || |. .. |.||.|||..
YHIGRKIGSGSFGCVYKCHHKGTGKIVAVKIIKKR-HEKSWKDQTHRRLSEIQIMKRLNHPNIVRLYDW
Kinase 26669.AA QIK 641-710 41 2.5e-14 52.07 In-house 1-69 (272) Show / Hide 
Range on Protein: 641-710
Range on HMM: 1-69/272
Sequence Identity: 41% (29 aa)

FQILDTLGKGSYAQVKLAIDKRTNQKIAIKIYEKFKLTDPNKFKNVRREINILSKMTHENIIRLYHVIDT
. |  |.||| .| ||||  . | .|.||||  | .|.  | .. . ||. |.  . | .||.|| |. |
YDIERTIGKGNFAVVKLARHRITKTKVAIKIIDKSQLDEEN-LQKCYREVQIMKMLYHPHIIKLYQVMET
Kinase 26669.AA Ciliate-E2 641-705 18 6e-13 40.77 In-house 1-98 (365) Show / Hide 
Range on Protein: 641-705
Range on HMM: 1-98/365
Sequence Identity: 18% (18 aa)

FQILDTLGKGSYAQVKLAIDKRT-----------------------NQKIAIKIYEKFKLTDPNKFKNVRREIN----------ILSKMTHENIIRLY
. ..  .|.|....|... ....                       ....|.||..| ..   .. ... ||||          ||... | |||..|
YKFIKKIGQGNFGSVYKCKVWKVQKQFAIKIIDQKQQRQQMQEKVKIKIYAMKIMKKNQIEQIKQEIHIMREINCFYKKINEKNILEQLNHPNIIKMY
Kinase 26669.AA TyrKc 641-858 18 7.9e-12 -31.4 SMART 1-280 (280) Show / Hide 
Range on Protein: 641-858
Range on HMM: 1-280/280
Sequence Identity: 18% (53 aa)

FQILDTLGKGSYAQVKLAIDKRTNQKIAIKIYEKFKLTDPNKFKNVRREINILSKM--THENIIRLYHVIDTV-------SSII----------------
 . ...|| | . .| ... |   .. |.|   . .       .  .||..|..|    |.||.||| |. .          .                 
ITLGKKLGEGAFGEVYKGTWK---IQVAVKMLKEDA------REDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPHGDLKDYLR

-------------------SGIQYMHNKNVCHRDIKLENILIDDDLNLKIIDFGFAVVSPIE-----RKLDSFC----GTPS-----YMSPEIVLKKEYI
                   .| .| | ||. |||.   |.|.....  || ||| .     .     .|         |. .      |.||   .... 
KHRPKLCMKDLLSFCWQIACGMEYLHSKNCIHRDLAARNCLVGENHTVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGKTMLPIRWMAPECINYGKF-

GQYVDIWTCGIVLY-ILICGKFPFKG-----ADEKELYRKISKHQYEIPSFV---------ERGARSLIQRLLSFNPEDRPSCLEILKDKW
    |.|  |.... |.  |. |  |      . .|..... .  .  .                 .....   ..|||||.  || ....
TTKSDVWSFGVCMWEIFTYGQQPYPGMIQQMMSNQEVIEYVKQGYRMPQPPNDYPMSFVCCPDEMYQIMKQCWHEDPEDRPTFSEI-HECF
Kinase 26669.AA Pkinase_Tyr 641-708 25 2.5e-08 28.85 Pfam 1-73 (270) Show / Hide 
Range on Protein: 641-708
Range on HMM: 1-73/270
Sequence Identity: 25% (19 aa)

FQILDTLGKGSYAQVKLAIDK----RTNQKIAIKIYEKFKLTDPN-KFKNVRREINILSKM-THENIIRLYHVI
 ... .||.|.. .|.... |     |... |.|.  | . .... . .   ||..|....  |.||.||| |.
ITFGKKLGEGAFGEVYKGTWKGDPDNTKIPVAVKML-KEGAMHEQNCREDFMREAKIMKQLGHHPNIVRLYGVC
Kinase 26669.AA APH 726-757 25 0.000356 15.12 Pfam 172-207 (248) Show / Hide 
Range on Protein: 726-757
Range on HMM: 172-207/248
Sequence Identity: 25% (9 aa)

VCHRDIKLENILID--DDLNLK--IIDFGFAVVSPI
.||.| .. |...|  .| .    .||...|.. ..
WCHGDFHPGNVMWDPRPDGGRVTGVIDWDDACWGDP
Kinase 26669.AA Pkinase_Tyr 716-750 40 0.041056 7.78 Pfam 122-156 (270) Show / Hide 
Range on Protein: 716-750
Range on HMM: 122-156/270
Sequence Identity: 40% (14 aa)

SGIQYMHNKNVCHRDIKLENILIDDDLNLKIIDFG
.| .| ..||  |||.   |.|.....  || |||
KGMEYLESKNCIHRDLAARNCLVTENNVVKICDFG