Gene 28996 (Tetrahymena)

28996

Species: Tetrahymena
Alias: PreTt28996, TTHERM_00577090, 3812.m02685, 28996, 224, 77.m00208
External Links: Tetrahymena Genome Database (TGD)
Annotation:

Classification

Group: CAMK
Family: CAMKL
Subfamily: MARK

Sequence

Name Sequence Type Origin Length Description Download
28996.AA Protein None 917 None Fasta, JSON
28996.kin_dom Protein Kinase Domain None 255 None Fasta, JSON
28996.NA RNA None 2754 None Fasta, JSON

Protein domain

Protein domains of 28996.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Kinase 28996.AA MARK 639-893 52 1.6e-168 554.82 In-house 1-262 (262) Show / Hide 
Range on Protein: 639-893
Range on HMM: 1-262/262
Sequence Identity: 52% (138 aa)

FEMGAKIGTGSYAVVNLAIDKRTNQKVAIKVYEKEKLQDPHKMKNVKREVQILSHISHFNIIKLYYVID--APTT-LNLVMEYIGTSSLYSYLKAKPNRR
..|.  ||.||||.| ||..|.|..|||||.|||.||.||..||||.||..|.....| |||||..||.   ... ..|.|||..  .||.|.||.||.|
YKMLKTIGHGSYAKVKLACHKHTGRKVAIKIYEKFKLNDPQWMKNVMREIEIMKKLDHPNIIKLFHVIEQDTEQHQIYLIMEYASGGELYDYIKAHPNGR

LPENDARKIFRQVVEGIKYLHSRNIIHRDIKLENLLIDDYK--NVKIIDFGFAVCAPKDKKLTSFCGTPSYMAPEIVSKKDYYGAPVDVWTCGVLLFVLF
|.|..||.||||.|....|.||.||.|||||.||.|||. .  |.|||||||..| | ..||..|||||.||||||..||.|.| .||.|..||.|... 
LHEEEARRIFRQIVSAVNYCHSKNIVHRDIKPENILIDENGNHNIKIIDFGFSICIPPGQKLNTFCGTPPYMAPEIFLKKPYDGPKVDIWSLGVVLYFMV

CGAFPFR--GNDEKDLYKKIQKCQLEVPPHVPPGAKLLIQRILKPVPKERPDVEEILKDPWV
|| |||.  ..|.|.|||||.... ..|.||..... ||||.|.. |.|||..|||.|.||.
CGYFPFDGDTQDYKELYKKILRGKYDIPCHVSKECRNLIQRLLTVNPEERPTIEEIMKHPWM
Kinase 28996.AA CAMKL 639-893 38 1.2e-144 464.6 In-house 1-297 (297) Show / Hide 
Range on Protein: 639-893
Range on HMM: 1-297/297
Sequence Identity: 38% (114 aa)

FEMGAKIGTGSYAVVNLAID-KRTNQKVAIKVYEKEKLQ-DPHKMKN-----------VKREVQILSHIS---HFNIIKLYYVIDAPTT------LNLVM
...|  .|.||...| ||.. . |..|||||...|.|.. ||...||           ..||.||.....   | |||||| ||. |..      ..|||
YRIGKTLGKGSFGKVKLATHIRTTGEKVAIKIIDKKKIWNDPWMKKNKCGQKHESDMRIRREIQIMKMLNIGKHPNIIKLYEVIETPEHDIETKKIYLVM

EYIGTSS--LYSYLKAKPNRR--LPENDARKIFRQVVEGIKYLHSRNIIHRDIKLENLLIDDYK--NVKIIDFGFA---V-C-APKDKKLTSFCGTPSYM
||..  .  |. |......||  .||..||..|||.|....|.||..|.|||||.||.|.|. .  |.|||||||.     |  ....||. |||.|.||
EYCSGGEMDLFDYIVKHGHRRGRMPEHEARRYFRQIVSAVNYCHSHGIVHRDIKPENILLDENGNNNIKIIDFGFSNMYRPCIFGPGQKLKTFCGSPPYM

APEIVSK--KDYYGAPVDVWTCGVLLFVLFCGAFPFR-------GNDEKDLYKKIQKCQLEVPP---HVPPGAKLLIQRILKPVPKERPDVEEILKDPWV
||||...  |.|.| .||.| |||.|... ||..||.       |.| . .......|. . ||   ||.  .. ||...|.. |..|| ...|...||.
APEIFQGNNKPYDGPKVDIWSCGVILYAMVCGYLPFDDDTYNKQGKDNI-YLYWKIMCG-YYPPIWYHVS-DCRDLIRKMLQVNPEKRPTIHQIMNHPWM
Kinase 28996.AA CAMK 644-893 26 6.5e-126 407.95 In-house 1-425 (425) Show / Hide 
Range on Protein: 644-893
Range on HMM: 1-425/425
Sequence Identity: 26% (112 aa)

KIGTGSYAVVNLAIDKRTN------------QKVAIKVYEKEKLQD-------------------------PHKMKNVKREVQILSH-------ISHFNI
..|.||...| |.|.|.|.            ||||||...|.||.|                         |...|||.||..|...       ..| ||
TLGRGSFGKVKLCIHKNTTGKERVHHIYTNGQKVAIKIIDKKKLKDKQNQDYSNCYKIDKSKCKHRYCWRRPKDRKNVRREIEIMKKLQGIGNKLDHPNI

IKLYYVID------------APTT--------LNLVM---EYIGTS----SLYSYLKAKPN-------------RRLPENDARKIFRQVVEGIKYLHSRN
|||| |..              ..        . .||   ||.        |..|......             .|..| .||..|||......|.||.|
IKLYEVYEDPHYFKNTNDYET-SKQVFTKDKHMYMVMEIMEYCSGGELFDDLFDYIVEHGCYGEEFDQFDIVERGRFTEREARRYFRQICSAVHYCHSHN

IIHRDIKLENLLIDDYK-----------------NVKIIDFGFAVCAPK------------------------DKKLTSFCGTPSYMA-PEIVSK-----
|.|||.|.||.|.|| .                 |.||||||||   ..                        ..|.. |||||.||| ||....     
IVHRDLKPENILLDDNNDDSDPVEHDEIFDWNNNNIKIIDFGFANKFDPGENNFMCSDYKGGEMHNQWTTPTEGQKMKTFCGTPEYMAAPEVLNGKGHCN

--------KDYYGAPVDVWTCGVLLFVLFCGAFPFRGN-------------DEKDLYKKIQKCQLE-VPPHVPP-----------------------GAK
        |.||| ..|.| |||.|... || .||.|              ....|..||.|.. .  ||...|                        .|
MQNATDEEKPYYGPKCDMWSCGVILYIMLCGYPPFYGDCDNEICEDEWIGMNDYELFEKIMKGKYDFPPPYFSPISCNYGPEWWDDISDEFHHFVSQECK

LLIQRILKPVPKERPDVEEILKDPWV
 ||...|.. |..|. .|..|..||.
DLIRKMLQVDPEKRMTIEQCLNHPWM
Kinase 28996.AA S_TKc 639-893 34 5.2e-103 349.45 SMART 1-231 (231) Show / Hide 
Range on Protein: 639-893
Range on HMM: 1-231/231
Sequence Identity: 34% (93 aa)

FEMGAKIGTGSYAVVNLAIDKRTNQKVAIKVYEKEKLQDPHKMKNVKREVQILSHISHFNIIKLYYVIDAPTTLNLVMEYIGT--SSLYSYLKAKPNRR-
.|.. ||| |....| ....|.|...||||.            ....||.|||..  | ||.|||.|..  . | .||||...   .|..|.| .. .. 
YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK----------EHIRREIQILKK-HHPNIVKLYDVFQD-DHLYMVMEYCDGDLGDLFDYIKKRGRHGL

---LPENDARKIFRQVVEGIKYLHSRNIIHRDIKLENLLIDDYKNVKIIDFGFAVCAPKDKKLTSFCGTPSYMAPEIVSKKDYYGA-PVDVWTCGVLLFV
   .|| .||....|......|.||..|||||.| ||.|.|.  ..||.|||.|         |.||||| |||||..     ||  ..|.| ||..|. 
RFPFPE-HARFYMYQICCALEYCHSHGIIHRDLKPENILLDE--HIKICDFGLARQL------TTFCGTPWYMAPEVL----GYGKCKCDWWSCGCILYE

LFCGAFPFRGNDEKDLYKKIQKCQLEVPPHVPPGAKLLIQRILKPVPKERPDVEEILK-------DPWV
..||  ||.  ... ..|||           .| || .|...|.  |..|| . |.|.       .||.
MLCGYPPFP--QMQMMFKKIG----------SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF
Kinase 28996.AA AMPK 639-893 38 1.5e-102 305.24 In-house 1-254 (254) Show / Hide 
Range on Protein: 639-893
Range on HMM: 1-254/254
Sequence Identity: 38% (99 aa)

FEMGAKIGTGSYAVVNLAIDKRTNQKVAIKVYEKEKLQDPHKMKNVKREVQILSHISHFNIIKLYYVI-DAPTTLNLVMEYIGTSSLYSYLKAKPNRRLP
. .| .||.|..  | ... ..|..|||||. .|.|..|   .. ..||..||  . | .||.|| || . || . .||||.    |..|   .  .||.
YIIGKTIGEGTFGKVKMGTHILTGEKVAIKILNKQKIKDQDMVERIQREIHILKLFRHPHIIQLYEVIIETPTDIFMVMEYVSGGELFDYIVKH--GRLQ

ENDARKIFRQVVEGIKYLHSRNIIHRDIKLENLLIDDYKNVKIIDFGFAVCAPKDKKLTSFCGTPSYMAPEIVSKKDYYGAPVDVWTCGVLLFVLFCGAF
| .|.. | |.. |. |.|  .| ||| |.||||.|. ||.|| |||      . ..|   || | | |||..| | | |  ||.| ||| |... ||  
EREACRFFQQIISGVEYCHRHMIVHRDLKPENLLLDHNKNIKIVDFGLSNMMKDGEFLKTACGSPCYAAPEMISGKLYCGPEVDIWSCGVILYAMLCGYL

PFRGNDEKDLYKKIQKCQLEVPPHVPPGAKLLIQRILKPVPKERPDVEEILKDPWV
||   .  .||||| ... ..| .. | || ||...|.. | .| ....| ..|| 
PFDDENTPTLYKKIKNGEYYIPKFLSPEAKDLIKHMLQVDPMKRITIHDIRNHPWF
Kinase 28996.AA Aur 639-893 38 5.8e-102 269.73 In-house 1-257 (257) Show / Hide 
Range on Protein: 639-893
Range on HMM: 1-257/257
Sequence Identity: 38% (99 aa)

FEMGAKIGTGSYAVVNLAIDKRTNQKVAIKVYEKEKLQDPHKMKNVKREVQILSHISHFNIIKLY-YVIDAPTTLNLVMEYIGTSSLYSYLKAKPNRRLP
||.|.. | |..  | ||..| |....|.|| .|| ..     ....||. | || .| ||.|.| | .|. .   |..||    .||..|. .||.|..
FEIGKPLGKGKFGNVYLARHKKTHFIFALKVMFKEQIKKYCMEHQLRREIKIQSHLNHPNILKMYGYFHDD-QRIYLILEYAPGGELYKELQKQPNKRFD

ENDARKIFRQVVEGIKYLHSRNIIHRDIKLENLLIDD-YKNVKIIDFGFAVCAPKDKKLTSFCGTPSYMAPEIVSKKDYYGAPVDVWTCGVLLFVLFCGA
|. | |...|. ....|.||.|||||||| ||.|.|. . |.|| ||| .| .|. .. . ||||  ||.||.|. .. ..  ||.|  |||.. |  |.
EQRAAKYMYQICNALDYCHSKNIIHRDIKPENILLDQCNGNIKICDFGWSVHCPNNNRRMTFCGTLDYMPPEMVEGQM-HDHKVDIWCLGVLCYELCHGC

FPFRG-NDEKDLYKKIQ-KCQLEVPPHVPPGAKLLIQRILKPVPKERPDVEEILKDPWV
 || . .. .  |..|. |.... |.|....|| ||..||.  ||.|   ..|.. ||.
PPFESNENHDETYDRIKNKVDIQFPSHISKEAKDLISKILQHDPKQRMTLDQIMNHPWI
Kinase 28996.AA AGC 639-893 22 8e-100 258.15 In-house 1-395 (395) Show / Hide 
Range on Protein: 639-893
Range on HMM: 1-395/395
Sequence Identity: 22% (91 aa)

FEMGAKIGTGSYAVVNLAIDK------RTNQKVAIKVYEKEK---LQDPHKMKNVKRE------------VQILSHIS----------HFNIIK-LYYVI
||.   ||.||.  | |. .|       |..  |.|| .|..   . . ........|             .||....          | .|.| |.|  
FEFLKVIGKGSFGKVYLVRKKDGCHKKDTGKYYAMKVLKKKHKIVIKKKNMVEHTMTEHWKQDQGYVWEERNILEKCNHTHNHPIKSHHPFIVKILHYSF

DAPTT--LNLVMEY---------IGTS-SLYSYLKAK-PNRRLPENDARKIFRQ-------VVEGIKYLHS-RNIIHRD-IKLENLLIDDYKNVKIIDFG
  ..   | .||||         .|    |...|. .  ..|..|. || .. .       .| .. |||| ..||||| .|.||.|.|.  ..|. |||
QDKDHTYLYFVMEYMPRYVNDLYCGGGCELFLHLQGRRKEGRFDEERARFYAAEMQKICGCIVLALEYLHSHMGIIHRDYLKPENILLDEDGHIKLTDFG

FAVCAPKD---------------------------------------------------KKLTSFCG--TPSYMAPEIVSKKDYYGAPVDVWT--CGVLL
..   ..|                                                   .. ..|||  || ||||||.     || ..| |.   |.|.
LCKEGMNDGEKGQQSQSNMKFHWHNKKYQKSNMDTNKCNPNNWQRNNMSQEDDTTRKKRDRTWTFCGPCTPEYMAPEIL-----YGKACDWWSFGLGCLM

FVLFCGAFPFRGN----------DEKDLYKKIQ------KCQLEVP----------PHVPPGAKLLIQRILKPVPKERPD----------VEEILKDPWV
. . .|  ||.|.          .......||.      ..... |          ... | || ||.. |.. |..|.           .||| . || 
YEMLTGYPPFYGDNPQENRHPFRNPMEMFQKIMNGRYFINWKVKFPFPEDPQFPEDRWFSPEAKDLIKKLLCKDPEKRLGCGGNDFGDKGAEEIKNHPWF
Kinase 28996.AA Pkinase 639-893 30 3.3e-96 330.74 Pfam 1-293 (293) Show / Hide 
Range on Protein: 639-893
Range on HMM: 1-293/293
Sequence Identity: 30% (90 aa)

FEMGAKIGTGSYAVVNLAIDKRTNQKVAIKVYEKEKLQDPHKMKNVK-REVQILSHISHFNIIKLYYVIDAPTTLNLVMEYIGTS----SLYSYLKAKPN
.. | ||| ||...| ....| |...||.|. .|..  .  .. ... .|.||. ...| ||..||..   .. . .|||| .      .|..|.... .
YHIGRKIGSGSFGCVYKCHHKGTGKIVAVKIIKKRHEKSWKDQTHRRLSEIQIMKRLNHPNIVRLYDWFEDKDHIYMVMEYCEGGLYVMDLFDYISTWRH

RRL--PENDARKIFRQVVEGIKYLHSRNIIHRDIKLENLLIDDYKNV----KIIDFGFAVC--APKDKKLTSFCGTPSYMAPEIVSKKDYYGAPVDVWTC
...  .|........|...|..|.||..|||||.|.||.|||.  ..    ||.|||.| .    ..  .|.||||| |||||.. .  ||| .||.| |
GCFYFSEWECKFYMYQILRGLEYCHSMGIIHRDLKPENILIDNNGHIDACVKICDFGLAKQFDY-NNS-MTTFCGTPWYMAPEVIRGGQYYGPKVDMWSC

GVLLFVLFCGAFPFRGN------DEKDLYKKIQKCQLEVPPHVP---------------------PGAKLLIQRILKPVPKERPDVEEILKDPWV
|..|. ..|| .||.|       |.. ....| ...|. .   .                     . .| .| ..|.. ||.||  |.||..||.
GCILYEMLCGRPPFPGHCWHDNHDQMQMICRIMGPPLHFDWPWWCSISYFFFRHWHFHWTFHNWSEECKDFIKWCLCKDPKKRPTAEQILQHPWF
Kinase 28996.AA NuaK 639-893 38 7.5e-92 241.7 In-house 1-252 (252) Show / Hide 
Range on Protein: 639-893
Range on HMM: 1-252/252
Sequence Identity: 38% (99 aa)

FEMGAKIGTGSYAVVNLAIDKRTNQKVAIKVYEKEKLQDPHKMKNVKREVQILSHISHFNIIKLYYVIDAPTTLNLVMEYIGTSSLYSYLKAKPNRRLPE
.|.  . | | |  | ||... | ..||||   |.| .|.. |  . ||..|.| . | .||. | |      . .||||     || |.  .  ..|||
YEFQKTLGKGTYGKVKLATEHSTGREVAIKSIKKCKIEDEQDMVHIRREIEIMSSLNHPHIIHIYEVFENKDKIVIVMEYASGGELYDYISEC--KSLPE

NDARKIFRQVVEGIKYLHSRNIIHRDIKLENLLIDDYKNVKIIDFGFAVCAPKDKKLTSFCGTPSYMAPEIVSKKDYYGAPVDVWTCGVLLFVLFCGAFP
..||..|||.|  . | |  .|.||| |||| | |.  |.|| |||      ..| |. ||| | |  ||||  . | |  || |  ||||...  |  |
REARHFFRQIVSAVHYCHKHRICHRDLKLENILLDQNCNAKIADFGLSNYYHDQKFLHTFCGSPLYASPEIVNGQPYHGPEVDCWSLGVLLYTMVYGTMP

FRGNDEKDLYKKIQKCQLEVPPHVPPGAKLLIQRILKPVPKERPDVEEILKDPWV
| |.| | | | |.. .    |. |  |  ||  .|.  |. |  ...| . .||
FDGHDFKHLVKQISQGAY-YEPCKPSDACMLIRWMLMVNPRRRATIYDICHHWWV
Kinase 28996.AA Ciliate-E2-Unclassified 639-893 25 8.8e-81 274.68 In-house 1-352 (352) Show / Hide 
Range on Protein: 639-893
Range on HMM: 1-352/352
Sequence Identity: 25% (90 aa)

FEMGAKIGTGSYAVVNLAIDKRTNQKV-----AIKVYEKEKLQDPHK---------MKNVK--------REVQ-ILSHISHFNIIKLYYVIDAPTTLNLV
.... .||.|....| ....| .. ..     ..|. .. ..|  .|         |.| |        .. | ||... | .|.|..|.     .. .|
YKIIKQIGQGGFGKVYKCQHKKQK-QYYAMKYMKKIQIYKQKQIMNKDEIMNEMKEMNNKKKYHQRKYNKIMQQILLNHPHPFIVKMFYCFQDKQNIYIV

MEYIGTSSLYSYLKAKPN---------------RRLPENDAR-----KIFRQVVEGIKYLHSRN-IIHRDIKLENLLIDDYK---NVKIIDFGFA----V
|||.   .|  |.| ...               ....|. |.     ..|.|...|..|||. | |||||||.||.|.|. .   ..||||||..     
MEYCEGGDLWQYIKKRKKQKQKGNDLFHNMKQRKIFTEQQAKYKKAKFYFAQILQGLEYLHHKNNIIHRDIKPENILFDNNGKNYYIKIIDFGISKKYQQ

C------------APKDKKLTSFCGTPSYM----APEIVSKKDYYG---APVDVWTCGVLLFVLFCGAFPFRGNDEKD----------------LYKKIQ
.             .|......|||||.||    |||.  .. |..     .|.|..||.|. .  | .|| .|....                ||..|.
NNNCDTNQQQKMQIWKQQMMWTFCGTPNYMPQYTAPEVLQGQNYDHSKAYKCDIWSLGVILYEMLFGYYPFYDNNCEQHQQLITQWINNAYRKQLYQNIK

KCQLEVPP--------HVPPGAKLLIQ----RILKPVPKERPDVEEILKDPWV
......|.        |..| || .|.    ..||  |..|.. |.||. || 
QKNIQFPKFPWQQIPKHWSPEAKDFINDLLQKMLKKNPNKRITFEQILNHPWF
Kinase 28996.AA Ciliate-E2 639-893 23 2.4e-76 259.92 In-house 1-365 (365) Show / Hide 
Range on Protein: 639-893
Range on HMM: 1-365/365
Sequence Identity: 23% (88 aa)

FEMGAKIGTGSYAVVNLAIDKRTNQ------------------KVAIKVYEKEKL--QDPHKMKNVKREVQ-------------ILSHISHFNIIKLYYV
..   |||.|....| .. ......                  ||.|| |... .  ..   .|..... .             ||....| ||||.|..
YKFIKKIGQGNFGSVYKCKVWKVQKQFAIKIIDQKQQRQQMQEKVKIKIYAMKIMKKNQIEQIKQEIHIMREINCFYKKINEKNILEQLNHPNIIKMYEC

ID--APTTLNLVMEYIGTSSLYSYLKAKPNRR---------LPENDARKIFRQVVE---------------GIKYLHSRN-IIHRDIKLENLLIDDYKNV
      ... |||||.   .|..|.| ..  |         . |. ...|..|...               ...||||.| |||||||.||.|.     .
FQEKDDNNIYLVMEYCQGGDLFDYIKNNKKKRNHEIEKDKYFTEKEIKYIMKQILQGFKTKAEFYIACIILALEYLHSKNNIIHRDIKPENILF-----I

KIIDFGFAVCAPKD--------------------------------KKLTSFCGTPSYMAPEIVSKKDY--------YGAPVDVWTCGVLLFVLFCGAFP
||||||..  . .|                                    ..|||| ||||||...|.|        |.  .|.| .||.|. . .| .|
KIIDFGLSKKYDDDNQNRTHKQQCKWYMFKNDTSRTPGYMDQIIQQNMFNTICGTPGYMAPEILNGKKYDNQQKQKGYDYKCDIWSLGVILYEMLFGKPP

FRGNDEKDLYKKIQKCQLEVP------------------PHVPPGAKLLIQR----ILKPVPKERPD-VEEILKDPWV
|        ...|..|... |                   .... .| ||..    .|.  |..|..  |.||. || 
F--------QQQIKQCKIDFPCPEWQKDTQCIQCKWKSWKKWSQECKDLIKKFGKRMLQKDPEKRITGWEQILNHPWF
Kinase 28996.AA QIK 639-893 34 1.9e-74 253.67 In-house 1-272 (272) Show / Hide 
Range on Protein: 639-893
Range on HMM: 1-272/272
Sequence Identity: 34% (94 aa)

FEMGAKIGTGSYAVVNLAIDKRTNQKVAIKVYEKEKLQDPHKMKNVKREVQILSHISHFNIIKLYYVIDAPTTLNLVMEYIGTSSLYSYLKAKPN-----
....  || | .||| ||  . | .|||||.  |..| |   .. ..|||||.  ..| .||||| |.     . .|.||     .. || ..       
YDIERTIGKGNFAVVKLARHRITKTKVAIKIIDKSQL-DEENLQKCYREVQIMKMLYHPHIIKLYQVMETDDMMYIVTEYCSNGEMFDYLCKHGRKGVKM

-------------RRLPENDARKIFRQVVEGIKYLHSRNIIHRDIKLENLLIDDYKNVKIIDFGFAVCAPKDKKLTSFCGTPSYMAPEIVSKKDYYGAPV
               ..||.||..| |.. ...|.|.|||.|||.| ||.|.|   |.||.||||     ... | ..||.| | |||.   |.| |  |
VNSPDIGDQVLMGVPMAENEARRWFWQICSAVHYCHKRNIVHRDLKAENILLDNNMNIKIADFGFSNWFKQGQLLMTWCGSPPYAAPEMFEGKEYDGPKV

DVWTCGVLLFVLFCGAFPFRGNDEKDLYKKIQKCQLEVPPHVPPGAKLLIQRILKPVPKERPDVEEILKDPWV
|.|  ||.|.|| |||.|| |   . | ...   .  .|. .. .   || . |   |. |  .. |.. .| 
DIWSMGVVLYVLVCGALPFDGKTLQNLRQRVLSGKFRIPFFMSQDCEHLIRHMLVVDPEHRYTIMQICQHRWM
Kinase 28996.AA Pkinase_Tyr 639-784 30 4.8e-22 75.29 Pfam 1-156 (270) Show / Hide 
Range on Protein: 639-784
Range on HMM: 1-156/270
Sequence Identity: 30% (48 aa)

FEMGAKIGTGSYAVVNLAIDK----RTNQKVAIKVYEKEKLQDPH-KMKNVKREVQILSHI-SHFNIIKLYYVID--APT-TLNLVMEYIGTSSLYSYLK
 ..| |.| |.. .| ... |     |...||.|.  ||.  ... ...   ||..|.... .| ||..|| |.        . .||||    .|..||.
ITFGKKLGEGAFGEVYKGTWKGDPDNTKIPVAVKML-KEGAMHEQNCREDFMREAKIMKQLGHHPNIVRLYGVCTDQGEPNQIYIVMEYMPHGDLLDYLR

AK--PNRRLPENDARKIFRQVVEGIKYLHSRNIIHRDIKLENLLIDDYKNVKIIDFG
..  ....|.  |  .. .|. .|  ||.|.|.||||.   | |... . ||| |||
KHREDKQPLTMKDLLQMCWQIAKGMEYLESKNCIHRDLAARNCLVTENNVVKICDFG
Kinase 28996.AA TyrKc 639-891 24 2.1e-17 58.76 SMART 1-280 (280) Show / Hide 
Range on Protein: 639-891
Range on HMM: 1-280/280
Sequence Identity: 24% (70 aa)

FEMGAKIGTGSYAVVNLAIDKRTNQKVAIKVYEKEKLQDPHKMKNVKREVQILSHI--SHFNIIKLYYVIDAP-------TTLNLVMEYIGTSSLYSYLK
 ..| |.| | . .| ... |   ..||.|.  ...      ..   || .|....  .| ||..|| |.  .         | .||||    .| .||.
ITLGKKLGEGAFGEVYKGTWK---IQVAVKMLKEDA------REDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPHGDLKDYLR

AKPNRRLPENDARKIFRQVVEGIKYLHSRNIIHRDIKLENLLIDDYKNVKIIDFGFAVCAPKD------KKLTSFC---GTPS-----YMAPEIVSKKDY
.. .. |.  |  ..  |. .|  ||||.|.||||.   | |... . ||| ||| .     |      |.  .     |. .      ||||   ..  
KHRPK-LCMKDLLSFCWQIACGMEYLHSKNCIHRDLAARNCLVGENHTVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGKTMLPIRWMAPECI-NYGK

YGAPVDVWTCGVLLF-VLFCGAFPFRG-----NDEKDLYKKIQKC-QLEVPPH--------VPPGAKLLIQRILKPVPKERPDVEEILKDP
.    |||  ||... ..  |. |  |      . .........   .. ||.         |.    ....  .  |..||  .|| .. 
FTTKSDVWSFGVCMWEIFTYGQQPYPGMIQQMMSNQEVIEYVKQGYRMPQPPNDYPMSFVCCPDEMYQIMKQCWHEDPEDRPTFSEIHECF
RIO 28996.AA RIO 625-811 14 0.000898 -102.82 SMART 1-253 (253) Show / Hide 
Range on Protein: 625-811
Range on HMM: 1-253/253
Sequence Identity: 14% (36 aa)

SSSRLSSGSVSLDTF---------------EMG--AKIGTGSYAVVNLAID---KRTNQKVAIKVYEKEKLQDPHKMKNVK-----R------EVQILSH
 .   .. ....|                 |..   .|.||  |.|  |     . .  ..|.|.|  ...    . ....     .          ...
DKEDYATYEEVFDPRTRMTLYKMVNRGYIEEINNHGCISTGKEANVYHAMGGDFDKNGNECAVKIYRTSTTEFKRMWRYIQGDFRFKHGYHHINWRKMVR

IS----HFNIIKLY-YVIDAPTTLN-----LVMEYIGTSSLYSYLKAKPNRRLPENDAR-KIFRQVVEGIKYLHSRN-IIHRDIKLENLLID-----DYK
..    . |  ..| ... .|.  .     ||||.||. ..  .   . .. ..| | . ... |..| .. .  .  ..| |    |.|..     .  
LWAEKEFRNLQRMYEAGVPCPKPIAWRRHVLVMEFIGDDGWPAPRLKDVEWEEWEMDFKWEYYWQIMEYMRKMYHECHLVHADLSEYNMLYHDLEDENDC

NVKIIDFGFAVCAPKD--------------------KKLTSFCGTPSYMAPEIVS
 | |||.. .|  ..|                    .| ..   .. ..  .|..
KVWIIDWSQSV--ECDHPMWLEFLERDIWNIINFFRRKGVDCDDIYREIFERITG
Kinase 28996.AA APH 760-790 20 0.000903 13.74 Pfam 172-206 (248) Show / Hide 
Range on Protein: 760-790
Range on HMM: 172-206/248
Sequence Identity: 20% (7 aa)

IIHRDIKLENLLID--DYKNVK--IIDFGFAVCAP
..|.| .. |...|  . ..    .||...|. ..
WCHGDFHPGNVMWDPRPDGGRVTGVIDWDDACWGD