Gene 19915 (Tetrahymena)
19915
Sequence
Protein domains of 19915.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.
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| Domain | Protein name | Domain Name | Range | Identity (%) | Significance | Score | Profile Source | Profile Range (length) | Alignment |
|---|---|---|---|---|---|---|---|---|---|
| Kinase | 19915.AA | CDPK | 145-402 | 57 | 1.1e-202 | 627.15 | In-house | 1-271 (271) | Show / Hide |
Range on Protein: 145-402 Range on HMM: 1-271/271 Sequence Identity: 57% (157 aa) YTIGKVIGEGGFGTVCLVRHK-TTQIDR-AMKMIPKKKLNKSDE-DKLFEELAILRQIDHPCIVKVFEHFQDEKYHYLISE--YCTGGELFERIKDVSPF |.|.||.|.|.||.|..| || |.. | |||.|||........ ...|.|..||.|.|||.|.|..|..||||..|.. | ||||||||..|.. ..| YKIKKVLGKGHFGQVRKVKHKQKTNQERVAMKIIPKSRVKDKEQQQQFFNEIEILKQLDHPNIIKIYEFYQDEKNYYIVMETEYCTGGELFDYIIEKGHF TEKVAAGYMKQILSAISYCHINNIVHRDLKPENILFDSKATNS----NLKVIDFGASTKFDHN-----EKLTKRIGTPFYVAPEILTKKPYDEKCDVWSL ||| ||..|.|||||..||| |||||||||||||||||| ..| |.||||.| |.|||.| .|...|.|||.|.|||.| || |.||||.||. TEKEAAYIMRQILSAVNYCHSNNIVHRDLKPENILFDSKKDDSWVIYNIKVIDWGTSKKFDQNQKIEDKKMSQRCGTPYYIAPEVLQKK-YNEKCDIWSC GVIMYILLCGYPPFWGQTDQEIYEKVKKGKFEFYDEDWADRSSDAKDLISKMLQYDPKDRISATEAYAHPWI |||.||||||||||.|..||||.|||||||..|....|.. |..|||||.|||.||||.|.|| .|..|||. GVILYILLCGYPPFYGKNDQEIMEKVKKGKYSFEGPEWDHISDEAKDLIRKMLCYDPKKRMSAQQALQHPWF |
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| Kinase | 19915.AA | CAMK1 | 145-402 | 46 | 4.1e-146 | 427.77 | In-house | 1-276 (276) | Show / Hide |
Range on Protein: 145-402 Range on HMM: 1-276/276 Sequence Identity: 46% (129 aa) YTIGKVIGEGGFGTVCLVRHKTT---QIDRAMKMIP-KKKLNKSDE---DKLFEELAILR---QIDHPCIVKVFEHFQDEKYHYLISEYCTGGELFERIK | .||.||.| |..| |. || | . . |.|.| || . |.|. ..| |..|.. .|||| |.| .|....... ||. |..||||||.|| YEFGKEIGRGAFSEVYLCTHKETQTNGKQYAIKCIDKKKFMKKKDMQKQEALENEIEIMKKVSKIDHPNIIKFYEWYESDNHFYLVMELVTGGELFDRIV DVSPFTEKVAAGYMKQILSAISYCHINNIVHRDLKPENILFDSKATNSNLK--VIDFGASTKFDHNE-KLTKRIGTPFYVAPEILTK---KPYDEKCDVW . .||| |. |||||||. |.| ..||||||||||.|. .| .| .| ..||| |..|||.| ..... ||| |||||.|. |||| .||.| EKGNYTEKDARHIMKQILSAVEYMHSKGIVHRDLKPENLLYYDKDEDSKIKRSIADFGLSKIFDHDENLMKTACGTPGYVAPEVLECKKDKPYDKACDMW SLGVIMYILLCGYPPFWGQT-DQEIYEKVKKGKFEFYDEDWADRSSD-AKDLISKMLQYDPKDRISATEAYAHPWI | ||| ||||||||||.. . |.|..||.||...|| | . |. |||.|..|| ||| |...... .|||| SIGVITYILLCGYPPFYDENVDNELFEKIKKCEYEFPSPWWDNISDQEAKDFIKHMLEVDPKKRYTCEQCLNHPWI |
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| Kinase | 19915.AA | CAMK | 150-402 | 30 | 3e-138 | 448.42 | In-house | 1-425 (425) | Show / Hide |
Range on Protein: 150-402
Range on HMM: 1-425/425
Sequence Identity: 30% (128 aa)
VIGEGGFGTVCLVRHK-TTQIDR-----------AMKMIPKKKLNKS--------------------------DEDKLFEELAILRQ-------IDHPCI
..|.|.||.| |..|| ||. | |.|.|.|||| .. |..... |..|... .|||.|
TLGRGSFGKVKLCIHKNTTGKERVHHIYTNGQKVAIKIIDKKKLKDKQNQDYSNCYKIDKSKCKHRYCWRRPKDRKNVRREIEIMKKLQGIGNKLDHPNI
VKVFEHFQD-------------------EKYHYLIS---EYCTGGEL----FERIKDVSP---------------FTEKVAAGYMKQILSAISYCHINNI
.| .|...| .|. |.. |||.|||| |..|.. .. |||. |. |..||.||. ||| .||
IKLYEVYEDPHYFKNTNDYETSKQVFTKDKHMYMVMEIMEYCSGGELFDDLFDYIVEHGCYGEEFDQFDIVERGRFTEREARRYFRQICSAVHYCHSHNI
VHRDLKPENILFDSKATNS--------------NLKVIDFGASTKFDH------------------------NEKLTKRIGTPFYVA-PEILTK------
|||||||||||.|.. ..| |.|.|||| ..|||. ..|.. . ||| |.| ||.| .
VHRDLKPENILLDDNNDDSDPVEHDEIFDWNNNNIKIIDFGFANKFDPGENNFMCSDYKGGEMHNQWTTPTEGQKMKTFCGTPEYMAAPEVLNGKGHCNM
--------KPYDEKCDVWSLGVIMYILLCGYPPFWGQ-------------TDQEIYEKVKKGKFEFYDED------------WADRSSD--------AKD
..|..|||.||.|||.||.|||||||.| .|.|..||..|||..|... | | | . .||
QNATDEEKPYYGPKCDMWSCGVILYIMLCGYPPFYGDCDNEICEDEWIGMNDYELFEKIMKGKYDFPPPYFSPISCNYGPEWWDDISDEFHHFVSQECKD
LISKMLQYDPKDRISATEAYAHPWI
||.||||.||..|...... .|||.
LIRKMLQVDPEKRMTIEQCLNHPWM
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| Kinase | 19915.AA | Ciliate-E2a | 145-402 | 44 | 2.5e-134 | 397.78 | In-house | 1-275 (275) | Show / Hide |
Range on Protein: 145-402 Range on HMM: 1-275/275 Sequence Identity: 44% (123 aa) YTIGKVIGEGGFGTVCLVRHKTTQIDRAMKMIPKKKLNKSD--EDKLFEELAILRQIDHPCIVKVFEHFQDEKYHYLISEYCTGGELFERIKDVSPFTEK | . |.||.| || | |..|| | ..||| . | |.. .. . ... |..|.||.||| | | .| ..||.. ||. ||| ||||...|| |.|. YKFIKKIGKGNFGSVYLAQHKQTGKQFAMKKFIK-KMYQQKKGKEYFMNEINIMRQLDHPNIIKLYEVYEDENNYYLVMEYCEGGELYDKIKQCKRFFEE --VAAGYMKQILS-AISYCHINNIVHRDLKPENILFDS-KATN---SNLKVIDFGASTKF--DHNEKLTKRIGTPFYVAPEILTKKP------YDEKCDV ... .|.|.|. ...|.| .||.|||||||||||.. .... |..|.|||| .|.. | .... .. ||| |||||.| | ||.|||. IQEICDIMQQLLWQGLHYMHQRNIMHRDLKPENILFKNCSKNSIQNSDIKIIDFGLATFIDKDEKKYMFQKCGTPGYVAPEVLNNKEVLKHKQYDTKCDM WSLGVIMYILLCGYPPFWGQTDQEIYEKVKKGKFEFYDED-WADRSSDAKDLISKMLQYDPKDRISATEAYAHPWI ||.|||.||||||.||| |.| .|| ...|| |. | . . | . |...|||..|||..||| ||.|..|. ||| WSCGVIFYILLCGKPPFKGKTYNEILQQNKKCKIDFNCPECWEKCSKECKDLMKKMLEKDPKKRITAQQALNHPWF |
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| Kinase | 19915.AA | S_TKc | 145-402 | 39 | 3.4e-115 | 389.92 | SMART | 1-231 (231) | Show / Hide |
Range on Protein: 145-402 Range on HMM: 1-231/231 Sequence Identity: 39% (107 aa) YTIGKVIGEGGFGTVCLVRHKTTQIDRAMKMIPKKKLNKSDEDKLFEELAILRQIDHPCIVKVFEHFQDEKYHYLISEYCTG--GELFERIKDVSP---- |.|...||.|.||.|...||| |. |.|.|. ... |..||.. .|| ||| ...||| .. |.. ||| | |.||..||. . YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK---------EHIRREIQILKK-HHPNIVKLYDVFQD-DHLYMVMEYCDGDLGDLFDYIKKRGRHGLR --FTEKVAAGYMKQILSAISYCHINNIVHRDLKPENILFDSKATNSNLKVIDFGASTKFDHNEKLTKRIGTPFYVAPEILTKKPYDE-KCDVWSLGVIMY |.| .|. ||.||..|. ||| ..|.||||||||||.|. ..|..||| .... | .|||.|.|||.| .|. |||.||.|.|.| FPFPE-HARFYMYQICCALEYCHSHGIIHRDLKPENILLDE-----HIKICDFGLARQL------TTFCGTPWYMAPEVL---GYGKCKCDWWSCGCILY ILLCGYPPFWGQTDQEIYEKVKKGKFEFYDEDWADRSSDAKDLISKMLQYDPKDRISATEAYA-------HPWI ..|||||||. ..|....|.. |..|||.|.|.||.||..|..| || . |||. EMLCGYPPFP--QMQMMFKKIG--------------SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF |
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| Kinase | 19915.AA | CAMKL | 145-402 | 37 | 7e-111 | 355.12 | In-house | 1-297 (297) | Show / Hide |
Range on Protein: 145-402 Range on HMM: 1-297/297 Sequence Identity: 37% (114 aa) YTIGKVIGEGGFGTVCLVRH-KTTQIDRAMKMIPKKKLN--------------KSDEDKLFEELAILRQID---HPCIVKVFEHFQDEKY------HYLI |.|||..|.|.||.| | .| .||.. |.|.| |||.. .||. ... | .|..... || |.| .|....... ||. YRIGKTLGKGSFGKVKLATHIRTTGEKVAIKIIDKKKIWNDPWMKKNKCGQKHESDM-RIRREIQIMKMLNIGKHPNIIKLYEVIETPEHDIETKKIYLV SEYCTGGE--LFERIKDV----SPFTEKVAAGYMKQILSAISYCHINNIVHRDLKPENILFDSKATNSNLKVIDFGASTKFD-H----NEKLTKRIGTPF ||| ||| ||..|. ...|. | | .||.||..||| ..|||||.||||||.|.. | |.|.|||| |.... . ..||. . |.| MEYCSGGEMDLFDYIVKHGHRRGRMPEHEARRYFRQIVSAVNYCHSHGIVHRDIKPENILLDENGNN-NIKIIDFGFSNMYRPCIFGPGQKLKTFCGSPP YVAPEILTK--KPYD-EKCDVWSLGVIMYILLCGYPPFWGQTD------QEIYEKVKKGKFEFYDEDWADRSSDAKDLISKMLQYDPKDRISATEAYAHP | ||||. . |||| | |.||.|||.| ..||| || ..|. |.. |. . .|. | . | |..|||.|||| .|..|... . || YMAPEIFQGNNKPYDGPKVDIWSCGVILYAMVCGYLPFDDDTYNKQGKDNI-YLYWKIMCG-YYPPIWYHVS-DCRDLIRKMLQVNPEKRPTIHQIMNHP WI | WM |
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| Kinase | 19915.AA | Ciliate-E2 | 145-402 | 30 | 3.4e-106 | 359.1 | In-house | 1-365 (365) | Show / Hide |
Range on Protein: 145-402 Range on HMM: 1-365/365 Sequence Identity: 30% (115 aa) YTIGKVIGEGGFGTVCLVRHKTTQIDR------------------AMKMIPKKKLNKSDEDKLFEELAILR----------------QIDHPCIVKVFEH | . |.||.|.||.|...... .| . ..|.. .| ..|.. .. |. |.| |..|| |.| .|. YKFIKKIGQGNFGSVYKCKVWKVQKQFAIKIIDQKQQRQQMQEKVKIKIYAMKIMKKNQIEQIKQEIHIMREINCFYKKINEKNILEQLNHPNIIKMYEC FQ--DEKYHYLISEYCTGGELFERIK------------DVSPFTEKVAAGYMKQILS---------------AISYCHINN-IVHRDLKPENILFDSKAT || |... ||. ||| ||.||..|| | .|||| .. .|||||. |. |.| .| |.|||.||||||| FQEKDDNNIYLVMEYCQGGDLFDYIKNNKKKRNHEIEKD-KYFTEKEIKYIMKQILQGFKTKAEFYIACIILALEYLHSKNNIIHRDIKPENILF----- NSNLKVIDFGASTKFD-----------HNEKLTKR----------------------IGTPFYVAPEILTKKP---------YDEKCDVWSLGVIMYILL .|.|||| |.|.| ..... . .||| |.||||| .|. ||.|||.||||||.|..| ---IKIIDFGLSKKYDDDNQNRTHKQQCKWYMF-KNDTSRTPGYMDQIIQQNMFNTICGTPGYMAPEILNGKKYDNQQKQKGYDYKCDIWSLGVILYEML CGYPPFWGQTDQEIYEKVKKGKFEFYDE--------------DWADRSSDAKDLISK----MLQYDPKDRIS-ATEAYAHPWI .|.||| ... |..|..| . .| . | ..||||.| |||.||. ||. . .. |||. FGKPPF--------QQQIKQCKIDFPCPEWQKDTQCIQCKWKSWKKWSQECKDLIKKFGKRMLQKDPEKRITGWEQILNHPWF |
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| Kinase | 19915.AA | Pkinase | 145-402 | 33 | 1.4e-104 | 358.52 | Pfam | 1-293 (293) | Show / Hide |
Range on Protein: 145-402 Range on HMM: 1-293/293 Sequence Identity: 33% (98 aa) YTIGKVIGEGGFGTVCLVRHKTTQIDRAMKMIPKKKLNKSDEDKLFE--ELAILRQIDHPCIVKVFEHFQDEKYHYLISEYCTGG----ELFERIK--DV |.||..||.|.||.|.. .|| |.. |.| |.|.. ... . .. |..|.. ..||.||. .. |.|... |.. ||| || .||..|. . YHIGRKIGSGSFGCVYKCHHKGTGKIVAVKIIKKRHEKSWKDQTHRRLSEIQIMKRLNHPNIVRLYDWFEDKDHIYMVMEYCEGGLYVMDLFDYISTWRH SPF--TEKVAAGYMKQILSAISYCHINNIVHRDLKPENILFD-SKATNSNLKVIDFGASTK--FDHNEKLTKRIGTPFYVAPEILT-KKPYDEKCDVWSL .| .|... ||.|||... ||| ..|.||||||||||.| ... .|..||| . . .|. .| . |||.|.|||.. ..|. |.|.||. GCFYFSEWECKFYMYQILRGLEYCHSMGIIHRDLKPENILIDNNGHIDACVKICDFGLAKQFDY-NNS-MTTFCGTPWYMAPEVIRGGQYYGPKVDMWSC GVIMYILLCGYPPFWGQ------TDQEIYEKVKKGKFEFYDEDWADRS-----------------SDAKDLISKMLQYDPKDRISATEAYAHPWI |.|.|..|||.|||.|. ...............| . | ..| ...||.|...|..|||.|..|... |||. GCILYEMLCGRPPFPGHCWHDNHDQMQMICRIMGPPLHFDWPWWCSISYFFFRHWHFHWTFHNWSEECKDFIKWCLCKDPKKRPTAEQILQHPWF |
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| Kinase | 19915.AA | RAD53 | 145-402 | 36 | 4.1e-102 | 304.98 | In-house | 1-305 (305) | Show / Hide |
Range on Protein: 145-402 Range on HMM: 1-305/305 Sequence Identity: 36% (113 aa) YTIGKVIGEGGFGTVCLVRHKTTQIDRAMKMIPKKKLN---KSD---EDKLFEELAILRQIDHPCIVKVFEHFQD-EKYHYLISEYCTGGELFERIKDVS | ..|..| |.|||| |. |.| |.| | |||.. .. .| . .|. ||. . ||||.. .. |.. .|| |.. |. ||||||..|.. YYMSKELGSGNFGTVKLAYEKKTCQKVAIKIIDKKKFFIRCMHTIKKMDQVMNEVEILKKLNHPCIIRIYDIFDTPQKYYYMVLELMTGGELFNKIVSNK P----FTEKVAAGYMKQILSAISYCHINNIVHRDLKPENILFDSKATNS---------------NLKVIDFGASTKFDHNEKLTKRI-GTPFYVAPEILT . |.| . | .|.. |..| | |.|.||||||||||..... . .|. ||| | || .. ..| ||| |||||..| RCQMGFDEDTCKYYFYQMCDAVKYLHDNGICHRDLKPENILCNHQDEECPQVQLGPWDEDEISFLIKITDFGLS-KFVGEGSFMKTMCGTPQYVAPEVIT KK---------------PYDEKCDVWSLGVIMYILLCGYPPFW-GQTD----QEIYEKVKK-GKFEFYDEDWADRSSDAKDLISKMLQYDPKDRISATEA .| | |.|.||.|.| ||.||||||| . |. ..|..|. ||..|. ..|.. |. |||||..||. ||. |... || SKGHNCYHENEERQVQVGYTKKVDCWSMGCILYICLCGYPPFSDDYTQEMHCMQLFEQIKNQGKYHFPHPYWDRISEEAKDLIKWMLCVDPEKRYTIDEA YAHPWI |||. LNHPWM |
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| Kinase | 19915.AA | CAMK-Unique | 145-402 | 28 | 7.79999999999e-102 | 336.97 | In-house | 1-363 (363) | Show / Hide |
Range on Protein: 145-402
Range on HMM: 1-363/363
Sequence Identity: 28% (103 aa)
YTIGKVIGEGGFGTVCLVRHKTTQIDRAMKMIPKKKLNKSDEDK------------------LFEELAILRQIDHPCIVKVFEH----FQDEK-------
|. ...||.|.|| | . ..| .|.||. |.. . . | .|..|.. |||.|.|... |.|.|
YKMHRIIGHGNFGHVYECMDRETGKKWACKMVKKQTHGNKKQKQQRNFDLRYKITEKRRDMKLKREHQIWKMVDHPNIIKLYDWNNPIFCDRKYPLCDLI
--------YHYLISEYCTGGELFERIKD--------------------VSPFTE--KVAAGYMKQILSAISYCHINNIVHRDLKPENILFDSKAT-----
| |.. |||.||.||. | . .|.| .. .| ..|||..| | ..|||||||.|||.. .
IKTPRALPYMYIVMEYCQGGDLFDWIQKWDEFYFNFIIKFDFNILKRCQGHFSERCWDTCFIMQCLLSAVAYMHSQDIVHRDLKLENIMVCYSFKDNNHH
--------NSNLKVIDFGASTKFDHNEKLT---KRIGTPFYVAP--------------EILTKKPYDEKC----DVWSLGVIMYILLCGYPPFWGQTDQ-
|...|..||| .....||.. . ...||| |.|| |.. .||..| | ||||||||..|||.||| ....
RDFPYDWSNWHIKLCDFGLCCHYNHNKMCHMMQTMCGTPCYMAPEIVFCKNYQEMTRDEVINMQCYDQQCSPASDIWSLGVIMYYMLCGCPPFDCECEDR
-------EIYEKVKKGKF-EFYDEDWAD---RSSDAKDLISKMLQYDPKDRISATEAYAHPWI
||.|. .||.. .| . | . | |||.. . ...||. |.|| |.. |.||
DYENHDKEIFECICKGDYCNFDWKMWHGPDYISQEAKDFVKCCMTVDPDHRWSAKELLEHQWI
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| Kinase | 19915.AA | Ciliate-E2-Unclassified | 145-402 | 31 | 4.4e-98 | 332.14 | In-house | 1-352 (352) | Show / Hide |
Range on Protein: 145-402 Range on HMM: 1-352/352 Sequence Identity: 31% (111 aa) YTIGKVIGEGGFGTVCLVRHKTTQIDRAMKMIP------KKKLNKSDEDKLFEELAILRQ------------------IDHPCIVKVFEHFQDEKYHYLI |.|.|.||.||||.|....|| .. |||.. .|. ...| ....|.... .. ..||.||| |..|||... |.. YKIIKQIGQGGFGKVYKCQHKKQKQYYAMKYMKKIQIYKQKQIMNKD-EIMNEMKEMNNKKKYHQRKYNKIMQQILLNHPHPFIVKMFYCFQDKQNIYIV SEYCTGGELFERIKDVSP-----------------FTEKVAA-----GYMKQILSAISYCHINN-IVHRDLKPENILFDSKATNSNLKVIDFGASTKFDH ||| ||.|.. ||. . |||. |. |..|||....|.| .| |.|||.||||||||.. | ..|.|||| | | . MEYCEGGDLWQYIKKRKKQKQKGNDLFHNMKQRKIFTEQQAKYKKAKFYFAQILQGLEYLHHKNNIIHRDIKPENILFDNNGKNYYIKIIDFGISKKYQQ N----------------EKLTKRIGTPFYV----APEILTKKPYD----EKCDVWSLGVIMYILLCGYPPFWGQTDQE----------------IYEKVK | .... ..||| | |||.| .. || .|||.||||||.| .| ||.|| .... . .|.. | NNNCDTNQQQKMQIWKQQMMWTFCGTPNYMPQYTAPEVLQGQNYDHSKAYKCDIWSLGVILYEMLFGYYPFYDNNCEQHQQLITQWINNAYRKQLYQNIK KGKFEFYDEDW----ADRSSDAKDLIS----KMLQYDPKDRISATEAYAHPWI .....| ..| . | |||.|. |||...|. ||.. .. |||. QKNIQFPKFPWQQIPKHWSPEAKDFINDLLQKMLKKNPNKRITFEQILNHPWF |
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| Kinase | 19915.AA | MARK | 145-402 | 41 | 2.3e-96 | 315.5 | In-house | 1-262 (262) | Show / Hide |
Range on Protein: 145-402 Range on HMM: 1-262/262 Sequence Identity: 41% (111 aa) YTIGKVIGEGGFGTVCLVRHKTTQIDRAMKMIPKKKLNK-SDEDKLFEELAILRQIDHPCIVKVFEHFQ--DEKY-HYLISEYCTGGELFERIKDV--SP | ..|.||.|....| |..|| |.. | |...|.|||. ... |..|....||| |.| |. .. .|. ||| ||. ||||...|| . . YKMLKTIGHGSYAKVKLACHKHTGRKVAIKIYEKFKLNDPQWMKNVMREIEIMKKLDHPNIIKLFHVIEQDTEQHQIYLIMEYASGGELYDYIKAHPNGR FTEKVAAGYMKQILSAISYCHINNIVHRDLKPENILFDSKATNSNLKVIDFGASTKFDHNEKLTKRIGTPFYVAPEILTKKPYD-EKCDVWSLGVIMYIL .|. | . .||.||..||| .||||||.|||||| |.. | | | |||| |... ..||. ||| | ||||. ||||| | |.|||||..|.. LHEEEARRIFRQIVSAVNYCHSKNIVHRDIKPENILIDENG-NHNIKIIDFGFSICIPPGQKLNTFCGTPPYMAPEIFLKKPYDGPKVDIWSLGVVLYFM LCGYPPFWGQT--DQEIYEKVKKGKFEFYDEDWADRSSDAKDLISKMLQYDPKDRISATEAYAHPWI .||| || |.| . |.|.|. .||..... | ....||...|. .|..|....| |||. VCGYFPFDGDTQDYKELYKKILRGKYDIPCH----VSKECRNLIQRLLTVNPEERPTIEEIMKHPWM |
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| Kinase | 19915.AA | TyrKc | 145-402 | 24 | 3.7e-17 | 54.76 | SMART | 1-280 (280) | Show / Hide |
Range on Protein: 145-402 Range on HMM: 1-280/280 Sequence Identity: 24% (72 aa) YTIGKVIGEGGFGTVCLVRHKTTQIDRAMKMIPKKKLNKSDEDKLFEELAILRQI--DHPCIVKVFEHFQDE-------KYHYLISEYCTGGELFERIKD | ||..||| ||.|.. . | |. | ||. . . . . .|. |.... .||.||. . .. . .... ||. .| | ..... ITLGKKLGEGAFGEVYKGTWK---IQVAVKMLKEDA-----REDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPHGDLKDYLRK VSP-FTEKVAAGYMKQILSAISYCHINNIVHRDLKPENILFDSKATNSNLKVIDFGASTKFDHN-----EKLTKRI----GTP-----FYVAPEILTKKP | .. | .. || . .| | .|..|||| |.| ... |. ||| | . .. .| ..| |. ||| . .. HRPKLCMKDLLSFCWQIACGMEYLHSKNCIHRDLAARNCLVGENH---TVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGKTMLPIRWMAPECINYGK YDEKCDVWSLGVIMY-ILLCGYPPFWG-----QTDQEIYEKVKKGKFEFYDEDWA------DRSSDAKDLISKMLQYDPKDRISATEAYAHPWI . .| |||| || |. |. | .| .| ..||..|.||.|. .. . . .... ..||.|| . .| | . FTTKSDVWSFGVCMWEIFTYGQQPYPGMIQQMMSNQEVIEYVKQGYRMPQPPNDYPMSFVCCPDEMYQ-IMKQCWHEDPEDRPTFSEI--HECF |
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| Kinase | 19915.AA | Pkinase_Tyr | 145-268 | 28 | 1.2e-12 | 43.51 | Pfam | 1-137 (270) | Show / Hide |
Range on Protein: 145-268 Range on HMM: 1-137/270 Sequence Identity: 28% (39 aa) YTIGKVIGEGGFGTVCLVRHK----TTQIDRAMKMIPKKKLNKSD--EDKLFEELAILRQI-DHPCIVKVFEHFQ-DEKY--HYLISEYCTGGELFERIK |.||..||| ||.|.. . | |.|. | ||. | . ... .....|..|..|. .|| ||. ... .|.. ||. .| | . . ITFGKKLGEGAFGEVYKGTWKGDPDNTKIPVAVKML-KEGAMHEQNCREDFMREAKIMKQLGHHPNIVRLYGVCTDQGEPNQIYIVMEYMPHGDLLDYLR D----VSPFTEKVAAGYMKQILSAISYCHINNIVHRDL . |.| | .. || .. .| . .|..|||| KHREDKQPLTMKDLLQMCWQIAKGMEYLESKNCIHRDL |
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| Kinase | 19915.AA | Pkinase_Tyr | 312-359 | 35 | 5e-06 | 21.17 | Pfam | 182-232 (270) | Show / Hide |
Range on Protein: 312-359 Range on HMM: 182-232/270 Sequence Identity: 35% (18 aa) APEILTKKPYDEKCDVWSLGVIMYILLC-GYPP-FWGQTDQEIYEKV-KKG ||| . . . .| |||| || |. .. | | ..| ...|.||.. ..| APECINYGKFTTKSDVWSFGVLMWEIFTYGEQPTYPGMSNEEVYEYIYEDG |
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| EFh | 19915.AA | EFh | 448-476 | 31 | 3e-06 | 27.81 | SMART | 1-29 (29) | Show / Hide |
Range on Protein: 448-476 Range on HMM: 1-29/29 Sequence Identity: 31% (9 aa) ELVKHFESLDTNGDGMLSKEELIEGYTKL |. . |. .|..||| ...||.... ..| EFKEMFRMFDKDGDGYIDFEEFKDMMKSL |
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| Efhand | 19915.AA | efhand | 448-476 | 41 | 1.6e-05 | 24.67 | Pfam | 1-29 (29) | Show / Hide |
Range on Protein: 448-476 Range on HMM: 1-29/29 Sequence Identity: 41% (12 aa) ELVKHFESLDTNGDGMLSKEELIEGYTKL || . |. .|..||| ...||..|...|| ELKEMFKEFDKDGDGYIDFEEFCEMMKKL |
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| Efhand | 19915.AA | efhand | 486-514 | 27 | 1e-05 | 25.39 | Pfam | 1-29 (29) | Show / Hide |
Range on Protein: 486-514 Range on HMM: 1-29/29 Sequence Identity: 27% (8 aa) TVENVFNDLDLDGSGKVEFSEFLVACLQK ....|...| ||.|...| ||. .. .. ELKEMFKEFDKDGDGYIDFEEFCEMMKKL |
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| EFh | 19915.AA | EFh | 486-514 | 27 | 3.2e-05 | 24.58 | SMART | 1-29 (29) | Show / Hide |
Range on Protein: 486-514 Range on HMM: 1-29/29 Sequence Identity: 27% (8 aa) TVENVFNDLDLDGSGKVEFSEFLVACLQK .. .|...| ||.|...| ||.... . EFKEMFRMFDKDGDGYIDFEEFKDMMKSL |
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| EFh | 19915.AA | EFh | 522-550 | 34 | 7.5e-09 | 36.66 | SMART | 1-29 (29) | Show / Hide |
Range on Protein: 522-550 Range on HMM: 1-29/29 Sequence Identity: 34% (10 aa) RIEKAFKLIDTDGNGQITKKELEEMMGGL ....|...|.||.|.|...|. .|| | EFKEMFRMFDKDGDGYIDFEEFKDMMKSL |
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| Efhand | 19915.AA | efhand | 522-550 | 41 | 1.8e-08 | 35.39 | Pfam | 1-29 (29) | Show / Hide |
Range on Protein: 522-550 Range on HMM: 1-29/29 Sequence Identity: 41% (12 aa) RIEKAFKLIDTDGNGQITKKELEEMMGGL .....||..|.||.|.|...|. ||| | ELKEMFKEFDKDGDGYIDFEEFCEMMKKL |
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| Efhand | 19915.AA | efhand | 556-584 | 24 | 0.000355 | 19.7 | Pfam | 1-29 (29) | Show / Hide |
Range on Protein: 556-584 Range on HMM: 1-29/29 Sequence Identity: 24% (7 aa) VWESLLKDCDVNQDGQISLTEFLDLLLNA .. . |. |...||.|.. ||.... . ELKEMFKEFDKDGDGYIDFEEFCEMMKKL |
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| EFh | 19915.AA | EFh | 556-584 | 24 | 0.002883 | 16.98 | SMART | 1-29 (29) | Show / Hide |
Range on Protein: 556-584 Range on HMM: 1-29/29 Sequence Identity: 24% (7 aa) VWESLLKDCDVNQDGQISLTEFLDLLLNA .. . .. |.. ||.|.. ||.|.. . EFKEMFRMFDKDGDGYIDFEEFKDMMKSL |
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