Gene 5812 (Tetrahymena)
5812
Sequence
Protein domains of 5812.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.
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Domain | Protein name | Domain Name | Range | Identity (%) | Significance | Score | Profile Source | Profile Range (length) | Alignment |
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Kinase | 5812.AA | CDPK | 272-528 | 61 | 1.7e-210 | 651.51 | In-house | 1-271 (271) | Show / Hide |
Range on Protein: 272-528 Range on HMM: 1-271/271 Sequence Identity: 61% (168 aa) YKIGEVLGEGAFGQVSKVVHK-STGMIR-AMKTIKKSSIIKEEE-DRLFSEMNILKNLDHPNILRLIELFQDNKNYYLVTE--YCSGGELFDKIKSMTHF |||..|||.|.|||| ||.|| .|...| |||.|.||.....|. ...| |..|||.||||||... | .||.||||.|.| ||.||||||.|... || YKIKKVLGKGHFGQVRKVKHKQKTNQERVAMKIIPKSRVKDKEQQQQFFNEIEILKQLDHPNIIKIYEFYQDEKNYYIVMETEYCTGGELFDYIIEKGHF TEKMAADYMKQILSAVVYCHQNNIVHRDLKPENLLFDSDKKNA----NLKVIDFGTSRKYDKA-----KKMSKRLGTPYYIAPEVLDQNYDEKCDVWSCG |||.||..|.||||||.|||.||||||||||||.||||.|... |.||||.|||.|.|.. ||||.|.|||||||||||...|.||||.|||| TEKEAAYIMRQILSAVNYCHSNNIVHRDLKPENILFDSKKDDSWVIYNIKVIDWGTSKKFDQNQKIEDKKMSQRCGTPYYIAPEVLQKKYNEKCDIWSCG VILYILLCGYPPFGGRSEDEILKKVRLGKFKFEPEDWDRISEEAKNLIKKMLTYDPKKRISAEQALNDAWI |||||||||||||.|... ||..||. ||..|| ..|| ||.|||.||.|||.||||||.||.|||.. |. VILYILLCGYPPFYGKNDQEIMEKVKKGKYSFEGPEWDHISDEAKDLIRKMLCYDPKKRMSAQQALQHPWF |
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Kinase | 5812.AA | CAMK1 | 272-528 | 44 | 8.99999999999e-155 | 453.38 | In-house | 1-276 (276) | Show / Hide |
Range on Protein: 272-528 Range on HMM: 1-276/276 Sequence Identity: 44% (122 aa) YKIGEVLGEGAFGQVSKVVHKST---GMIRAMKTIK-KSSIIKEEE---DRLFSEMNILKN---LDHPNILRLIELFQDNKNYYLVTEYCSGGELFDKIK |..|...|.|||..| ...||.| | |.| |. |... |... ..| | .|.|. .||||| ..| ..... .|||.|...||||||.| YEFGKEIGRGAFSEVYLCTHKETQTNGKQYAIKCIDKKKFMKKKDMQKQEALENEIEIMKKVSKIDHPNIIKFYEWYESDNHFYLVMELVTGGELFDRIV SMTHFTEKMAADYMKQILSAVVYCHQNNIVHRDLKPENLLFDSDKKNANLK--VIDFGTSRKYDKAK-KMSKRLGTPYYIAPEVLDQ----NYDEKCDVW ...||| |.. |||||||| |.|...||||||||||||. . . .. .| ..||| |...| .|... |||.|.||||| . || .||.| EKGNYTEKDARHIMKQILSAVEYMHSKGIVHRDLKPENLLYYDKDEDSKIKRSIADFGLSKIFDHDENLMKTACGTPGYVAPEVLECKKDKPYDKACDMW SCGVILYILLCGYPPFGGRS-EDEILKKVRLGKFKFEPEDWDRISEE-AKNLIKKMLTYDPKKRISAEQALNDAWI |.|||.|||||||||| . . ..|...|. ... | || ||.. ||..||.||. |||||...||.||. || SIGVITYILLCGYPPFYDENVDNELFEKIKKCEYEFPSPWWDNISDQEAKDFIKHMLEVDPKKRYTCEQCLNHPWI |
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Kinase | 5812.AA | Ciliate-E2a | 272-528 | 46 | 8.99999999999e-149 | 441.02 | In-house | 1-275 (275) | Show / Hide |
Range on Protein: 272-528 Range on HMM: 1-275/275 Sequence Identity: 46% (129 aa) YKIGEVLGEGAFGQVSKVVHKSTGMI-RAMKTIKKSSIIKEEEDRLFSEMNILKNLDHPNILRLIELFQDNKNYYLVTEYCSGGELFDKIKSMTHFTEK- ||. ..|.|.||.| .. || || ...| ||| ...|... .. | ||...||||||..|.| ..|..|||||.|||.||||.|||| |.|. YKFIKKIGKGNFGSVYLAQHKQTGKQFAMKKFIKKMYQQKKGKEYFMNEINIMRQLDHPNIIKLYEVYEDENNYYLVMEYCEGGELYDKIKQCKRFFEEI -MAADYMKQILS-AVVYCHQNNIVHRDLKPENLLFDS-DKKN---ANLKVIDFGTSRKY--DKAKKMSKRLGTPYYIA------PEVLDQN-YDEKCDVW ..|.|.|.|. .. |.||.||.||||||||.||.. .|.. ...|.||||..... |. |.| .. |||.|.| .||| .. ||.|||.| QEICDIMQQLLWQGLHYMHQRNIMHRDLKPENILFKNCSKNSIQNSDIKIIDFGLATFIDKDEKKYMFQKCGTPGYVAPEVLNNKEVLKHKQYDTKCDMW SCGVILYILLCGYPPFGGRSEDEILKKVRLGKFKFEPED-WDRISEEAKNLIKKMLTYDPKKRISAEQALNDAWI |||||.||||||.||| |....|||.... |. |. . | .| |.|.|.|||| .||||||.|.||||. | SCGVIFYILLCGKPPFKGKTYNEILQQNKKCKIDFNCPECWEKCSKECKDLMKKMLEKDPKKRITAQQALNHPWF |
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Kinase | 5812.AA | CAMK | 277-528 | 31 | 2.5e-138 | 448.67 | In-house | 1-425 (425) | Show / Hide |
Range on Protein: 277-528 Range on HMM: 1-425/425 Sequence Identity: 31% (133 aa) VLGEGAFGQVSKVVHK-STGMIR-----------AMKTIKKSSII--------------------------KEEEDRLFSEMNILKN-------LDHPNI .||.|.||.| ...|| .||..| |.| |.|. . . ......|..|.|. |||||| TLGRGSFGKVKLCIHKNTTGKERVHHIYTNGQKVAIKIIDKKKLKDKQNQDYSNCYKIDKSKCKHRYCWRRPKDRKNVRREIEIMKKLQGIGNKLDHPNI LRLIELFQD-------------------NKNYYLVT---EYCSGGEL----FDKIKSMTH---------------FTEKMAADYMKQILSAVVYCHQNNI ..|.| ..| .|..|.|. |||||||| ||.|.. .. |||. |. |..||.||| |||..|| IKLYEVYEDPHYFKNTNDYETSKQVFTKDKHMYMVMEIMEYCSGGELFDDLFDYIVEHGCYGEEFDQFDIVERGRFTEREARRYFRQICSAVHYCHSHNI VHRDLKPENLLFDSDKKN--------------ANLKVIDFGTSRKYDKAK------------------------KMSKRLGTPYYIA-PEVLDQN----- |||||||||.|.|..... .|.|.|||| ..|.|. . ||. . |||.|.| |||| .. VHRDLKPENILLDDNNDDSDPVEHDEIFDWNNNNIKIIDFGFANKFDPGENNFMCSDYKGGEMHNQWTTPTEGQKMKTFCGTPEYMAAPEVLNGKGHCNM ----------YDEKCDVWSCGVILYILLCGYPPFGGR-------------SEDEILKKVRLGKFKFEPED------------WDRISEE--------AKN |..|||.|||||||||.||||||| | .. |...|.. ||. |.|. ||.||.| .|. QNATDEEKPYYGPKCDMWSCGVILYIMLCGYPPFYGDCDNEICEDEWIGMNDYELFEKIMKGKYDFPPPYFSPISCNYGPEWWDDISDEFHHFVSQECKD LIKKMLTYDPKKRISAEQALNDAWI ||.|||..||.||...||.||. |. LIRKMLQVDPEKRMTIEQCLNHPWM |
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Kinase | 5812.AA | S_TKc | 272-528 | 41 | 2.9e-119 | 403.44 | SMART | 1-231 (231) | Show / Hide |
Range on Protein: 272-528 Range on HMM: 1-231/231 Sequence Identity: 41% (113 aa) YKIGEVLGEGAFGQVSKVVHKSTGMIRAMKTIKKSSIIKEEEDRLFSEMNILKNLDHPNILRLIELFQDNKNYYLVTEYCSG--GELFDKIKSMTH---- |.|....|.||||.| |..||.|| | |.| || ... .|..|||. .|||| .|.. ||| ...|.|.|||.| |.||| ||.. . YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK---------EHIRREIQILKK-HHPNIVKLYDVFQD-DHLYMVMEYCDGDLGDLFDYIKKRGRHGLR --FTEKMAADYMKQILSAVVYCHQNNIVHRDLKPENLLFDSDKKNANLKVIDFGTSRKYDKAKKMSKRLGTPYYIAPEVLDQNYDE-KCDVWSCGVILYI |.| .|. ||.||..|. |||...|.||||||||.|.|. ..|..||| .|.. . |||.|.||||| |. |||.||||.|||. FPFPE-HARFYMYQICCALEYCHSHGIIHRDLKPENILLDE-----HIKICDFGLARQL------TTFCGTPWYMAPEVL--GYGKCKCDWWSCGCILYE LLCGYPPFGGRSEDEILKKVRLGKFKFEPEDWDRISEEAKNLIKKMLTYDPKKRISAEQALN-------DAWI .||||||| .....||.. |.|||..|.|.|..||.||..| .||. . |. MLCGYPPFP--QMQMMFKKIG--------------SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF |
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Kinase | 5812.AA | CAMKL | 272-528 | 37 | 2.2e-113 | 363.22 | In-house | 1-297 (297) | Show / Hide |
Range on Protein: 272-528 Range on HMM: 1-297/297 Sequence Identity: 37% (112 aa) YKIGEVLGEGAFGQVSKVVH-KSTGMIRAMKTIKKSSII--------------KEEEDRLFSEMNILKNLD---HPNILRLIELFQDNKN------YYLV |.||..||.|.||.| .| . || |.| |.|. | . . |.. |..|.| |. |||| .| | ... .. .||| YRIGKTLGKGSFGKVKLATHIRTTGEKVAIKIIDKKKIWNDPWMKKNKCGQKHESDM-RIRREIQIMKMLNIGKHPNIIKLYEVIETPEHDIETKKIYLV TEYCSGGE--LFDKIKSMTH----FTEKMAADYMKQILSAVVYCHQNNIVHRDLKPENLLFDSDKKNANLKVIDFGTSRKYDK-----AKKMSKRLGTPY .||||||| |||.|.. | ..|. | | .||.||| |||...|||||.||||.|.|....| |.|.|||| | .|.. .|.. . |.| MEYCSGGEMDLFDYIVKHGHRRGRMPEHEARRYFRQIVSAVNYCHSHGIVHRDIKPENILLDENGNN-NIKIIDFGFSNMYRPCIFGPGQKLKTFCGSPP YIAPEVLDQ--N-YD-EKCDVWSCGVILYILLCGYPPFGGRSE------DEILKKVRLGKFKFEPEDWDRISEEAKNLIKKMLTYDPKKRISAEQALNDA | |||.. || | |.|||||||| ..||| || . . . ... . . ..| | ..| ....||.|||. .|.||....| .|. YMAPEIFQGNNKPYDGPKVDIWSCGVILYAMVCGYLPFDDDTYNKQGKDNI-YLYWKIMCG-YYPPIWYHVS-DCRDLIRKMLQVNPEKRPTIHQIMNHP WI | WM |
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Kinase | 5812.AA | Pkinase | 272-528 | 39 | 7.89999999999e-112 | 382.62 | Pfam | 1-293 (293) | Show / Hide |
Range on Protein: 272-528 Range on HMM: 1-293/293 Sequence Identity: 39% (116 aa) YKIGEVLGEGAFGQVSKVVHKSTGMIRAMKTIKKSSIIKEEEDRLFS--EMNILKNLDHPNILRLIELFQDNKNYYLVTEYCSGG----ELFDKIK--SM |.||...|.|.||.| | .||.|| | |.|.|||... .... ... | |.|.|.||||.||.. |.|....|.|.||| || .||| |. . YHIGRKIGSGSFGCVYKCHHKGTGKIVAVKIIKKRHEKSWKDQTHRRLSEIQIMKRLNHPNIVRLYDWFEDKDHIYMVMEYCEGGLYVMDLFDYISTWRH THF--TEKMAADYMKQILSAVVYCHQNNIVHRDLKPENLLFDSDKKN-ANLKVIDFGTSRK--YDKAKKMSKRLGTPYYIAPEVLD--QNYDEKCDVWSC . | .|. . .||.|||... |||...|.||||||||.|.|.. . | .|..||| ... | . |. . |||.|.||||. | |. |.|.||| GCFYFSEWECKFYMYQILRGLEYCHSMGIIHRDLKPENILIDNNGHIDACVKICDFGLAKQFDY-NNS-MTTFCGTPWYMAPEVIRGGQYYGPKVDMWSC GVILYILLCGYPPFGGR------SEDEILKKVRLGKFKFEPEDWDRIS-----------------EEAKNLIKKMLTYDPKKRISAEQALNDAWI |.|||..|||.||| |. .......... ....|. . |..|| ||.| .||..|..|||||..|||.|.. |. GCILYEMLCGRPPFPGHCWHDNHDQMQMICRIMGPPLHFDWPWWCSISYFFFRHWHFHWTFHNWSEECKDFIKWCLCKDPKKRPTAEQILQHPWF |
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Kinase | 5812.AA | Ciliate-E2 | 272-528 | 31 | 6e-110 | 371.58 | In-house | 1-365 (365) | Show / Hide |
Range on Protein: 272-528 Range on HMM: 1-365/365 Sequence Identity: 31% (122 aa) YKIGEVLGEGAFGQVSKVVHKSTG-----------------------MIRAMKTIKKS-SIIKEEEDRLF----------SEMNILKNLDHPNILRLIEL ||. ...|.|.||.| |. ..... .| |||..||. .... |.... |.|||..|.||||....| YKFIKKIGQGNFGSVYKCKVWKVQKQFAIKIIDQKQQRQQMQEKVKIKIYAMKIMKKNQIEQIKQEIHIMREINCFYKKINEKNILEQLNHPNIIKMYEC FQ--DNKNYYLVTEYCSGGELFDKIKSMTH-----------FTEKMAADYMKQILS---------------AVVYCHQNN-IVHRDLKPENLLFDSDKKN || |..|.|||.|||.||.||| ||.. . |||| ....|||||. |. |.|..| |.|||.||||.|| FQEKDDNNIYLVMEYCQGGDLFDYIKNNKKKRNHEIEKDKYFTEKEIKYIMKQILQGFKTKAEFYIACIILALEYLHSKNNIIHRDIKPENILF------ ANLKVIDFGTSRKYDKA-----------KKMSKR----------------------LGTPYYIAPEVLD-QN---------YDEKCDVWSCGVILYILLC .|.||||.|.|||. ..| . .|||.| |||.| .. ||.|||.||.|||||..|. --IKIIDFGLSKKYDDDNQNRTHKQQCKWYMF-KNDTSRTPGYMDQIIQQNMFNTICGTPGYMAPEILNGKKYDNQQKQKGYDYKCDIWSLGVILYEMLF GYPPFGGRSEDEILKKVRLGKFKFEPE--------------DWDRISEEAKNLIKK----MLTYDPKKRIS-AEQALNDAWI |.||| ... .|..| .. .|. .|.|.|.|||| || .||.|||. .||.|| |. GKPPF--------QQQIKQCKIDFPCPEWQKDTQCIQCKWKSWKKWSQECKDLIKKFGKRMLQKDPEKRITGWEQILNHPWF |
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Kinase | 5812.AA | CAMK-Unique | 272-528 | 30 | 7.50000000001e-108 | 357.16 | In-house | 1-363 (363) | Show / Hide |
Range on Protein: 272-528 Range on HMM: 1-363/363 Sequence Identity: 30% (111 aa) YKIGEVLGEGAFGQVSKVVHKSTGMIRAMKTIKK---SSIIKEE---------------EDRLFSEMNILKNLDHPNILRLIEL----FQDNK------- || ....|.|.|| | .. ..|| ..|.| .|| ..... . . | | .|.| .|||||..| . |.| | YKMHRIIGHGNFGHVYECMDRETGKKWACKMVKKQTHGNKKQKQQRNFDLRYKITEKRRDMKLKREHQIWKMVDHPNIIKLYDWNNPIFCDRKYPLCDLI --------NYYLVTEYCSGGELFDKIKS--------------------MTHFTE--KMAADYMKQILSAVVYCHQNNIVHRDLKPENLLFDSDKK----- ..|.|.||| ||.|||.| . .||.| .. .| ..|||| | |...|||||||.||... . | IKTPRALPYMYIVMEYCQGGDLFDWIQKWDEFYFNFIIKFDFNILKRCQGHFSERCWDTCFIMQCLLSAVAYMHSQDIVHRDLKLENIMVCYSFKDNNHH --------NANLKVIDFGTSRKYDKAKKMS---KRLGTPYYIAP--------------EVLD-QNYDEKC----DVWSCGVILYILLCGYPPFGGRSED- | ..|..||| ...|. |. . .. |||.|.|| ||.. | ||..| | ||.|||.|..|||.||| . .|| RDFPYDWSNWHIKLCDFGLCCHYNHNKMCHMMQTMCGTPCYMAPEIVFCKNYQEMTRDEVINMQCYDQQCSPASDIWSLGVIMYYMLCGCPPFDCECEDR -------EILKKVRLGKF-KFEPEDWDR---ISEEAKNLIKKMLTYDPKKRISAEQALNDAWI ||... . |.. .|. . |.. ||.|||...|. .|.||..|.||...| || DYENHDKEIFECICKGDYCNFDWKMWHGPDYISQEAKDFVKCCMTVDPDHRWSAKELLEHQWI |
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Kinase | 5812.AA | RAD53 | 272-528 | 36 | 7.6e-108 | 322.38 | In-house | 1-305 (305) | Show / Hide |
Range on Protein: 272-528 Range on HMM: 1-305/305 Sequence Identity: 36% (111 aa) YKIGEVLGEGAFGQVSKVVHKSTGMIRAMKTIKK---S---SIIKEEEDRLFSEMNILKNLDHPNILRLIELFQD-NKNYYLVTEYCSGGELFDKIK-SM | ....|| |.||.| ... |.|. |.| |.| . . .|.. .| .|||.| ||.| |... |.. |.||.| |. .|||||.||. . YYMSKELGSGNFGTVKLAYEKKTCQKVAIKIIDKKKFFIRCMHTIKKMDQVMNEVEILKKLNHPCIIRIYDIFDTPQKYYYMVLELMTGGELFNKIVSNK TH---FTEKMAADYMKQILSAVVYCHQNNIVHRDLKPENLLFDSDKKNA---------------NLKVIDFGTSRKYDKAKKMSKRLGTPYYIAPEVLD- . |.| . .| .|.. || | | |.|.|||||||| |....... .|. ||| |. .. | ||| | ||||. RCQMGFDEDTCKYYFYQMCDAVKYLHDNGICHRDLKPENILCNHQDEECPQVQLGPWDEDEISFLIKITDFGLSKFVGEGSFMKTMCGTPQYVAPEVITS ---------------QNYDEKCDVWSCGVILYILLCGYPPFG-GRSE----DEILKKVRL-GKFKFEPEDWDRISEEAKNLIKKMLTYDPKKRISAEQAL | |.|.|| |.||||.|||||||. .. . . . .... ||. |....|||||||||.|||.||. ||.||.....|| KGHNCYHENEERQVQVGYTKKVDCWSMGCILYICLCGYPPFSDDYTQEMHCMQLFEQIKNQGKYHFPHPYWDRISEEAKDLIKWMLCVDPEKRYTIDEAL NDAWI | |. NHPWM |
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Kinase | 5812.AA | Ciliate-E2-Unclassified | 272-528 | 34 | 1.5e-106 | 360.31 | In-house | 1-352 (352) | Show / Hide |
Range on Protein: 272-528 Range on HMM: 1-352/352 Sequence Identity: 34% (120 aa) YKIGEVLGEGAFGQVSKVVHKSTGMIRAMKTIKKSSIIK-----------EEEDRLFS-----------EMN-ILKNLDHPNILRLIELFQDNKNYYLVT |||....|.|.||.| |..||... . |||..||. |.| |...... .|. ||.|..||.|..... ||| .| |.|. YKIIKQIGQGGFGKVYKCQHKKQKQYYAMKYMKKIQIYKQKQIMNKDEIMNEMKEMNNKKKYHQRKYNKIMQQILLNHPHPFIVKMFYCFQDKQNIYIVM EYCSGGELFDKIKSMTH-----------------FTEKMAA-----DYMKQILSAVVYCHQNN-IVHRDLKPENLLFDSDKKNANLKVIDFGTSRKYD-- ||| ||.|.. ||.. . |||. |. .|..|||.. |.|..| |.|||.||||.|||...|| ..|.|||| |.||. EYCEGGDLWQYIKKRKKQKQKGNDLFHNMKQRKIFTEQQAKYKKAKFYFAQILQGLEYLHHKNNIIHRDIKPENILFDNNGKNYYIKIIDFGISKKYQQN --------------KAKKMSKRLGTPYYI----APEVLDQ-NYD----EKCDVWSCGVILYILLCGYPPFGGRSEDE----------------ILKKVRL | ..|. . |||.|. |||||.. ||| .|||.||.||||| .| ||.||....... .... NNCDTNQQQKMQIWKQQMMWTFCGTPNYMPQYTAPEVLQGQNYDHSKAYKCDIWSLGVILYEMLFGYYPFYDNNCEQHQQLITQWINNAYRKQLYQNIKQ GKFKFEPEDW----DRISEEAKNLIK----KMLTYDPKKRISAEQALNDAWI ....| ...| ...|.|||..|. ||| ..|.|||..||.|| |. KNIQFPKFPWQQIPKHWSPEAKDFINDLLQKMLKKNPNKRITFEQILNHPWF |
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Kinase | 5812.AA | RSK | 274-528 | 37 | 2.3e-96 | 326.45 | In-house | 1-278 (278) | Show / Hide |
Range on Protein: 274-528 Range on HMM: 1-278/278 Sequence Identity: 37% (106 aa) IGEV--LGEGAFGQVSKVVHKSTGMIRAMKTIKKSSIIKEEED--RLFSEMNILKNLD-HPNILRLIELFQDNKNYYLVTEYCSGGELFDKIKSMTH--- . . .| |.. .. |..|. ||.| ||| .||. |.. . | . . | |||. ||.| .| . ||... ||..|||.|||||.... | LKVLGQGGYGKVFLCRKCTHHDTGQIYAMKVLKKAKIVQRQKDTRHTMTERNILERCQQHPFIVTLHYAFQTEGKLYLIMEYCRGGELFTHLQKEKHFGC FTEKMAADYMKQILSAVVYCHQNNIVHRDLKPENLLFDSDKKN-ANLKVIDFGTSRK--YDKAKKMSKRLGTPYYIAPEVLD----QN-YDEKCDVWSCG |.|. |..|| .| .|| . || |.|||||||| |.|... | . .|..||| ... |. ... . .| |.|||.| |. .|. ||.|| | FSEDEACFYMAEIVLAVEHLHQQGIIHRDLKPENILYDDES-NEGHIKLTDFGFCKQFRCDHNQWTMTFCYTIEYMAPEMLKRANQQGGHDKACDWWSLG VILYILLCGYPPFGG---RSEDEILKKVRLGKFKFEPEDWDRISEEAKNLIKKMLTYDPKKRIS-----AEQALNDAWI |..| .| |.||| | . .||.|... ||| .. . |. .|.|||.||.|||. ||.||.. ||. ....|. VLMYEMLTGCPPFQGPNDNNRKEIMKRIQKGKFSLTMPNWQYLSQEAKDLIRKMLHRDPHKRLGCGPQDAEEIKQHPWF |
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Kinase | 5812.AA | TyrKc | 272-526 | 25 | 1.5e-22 | 82.17 | SMART | 1-280 (280) | Show / Hide |
Range on Protein: 272-526 Range on HMM: 1-280/280 Sequence Identity: 25% (73 aa) YKIGEVLGEGAFGQVSKVVHKSTGMIRAMKTIKKSSIIKEEEDRLFSEMNILKNL--DHPNILRLIELFQDN-------KNYYLVTEYCSGGELFDKIKS . |..|||||||.| | . | . | |..|... . . .|..|...| .||||.||. . . ...|.||...| | | ... ITLGKKLGEGAFGEVYKGTWK---IQVAVKMLKEDA-----REDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPHGDLKDYLRK MTH-FTEKMAADYMKQILSAVVYCHQNNIVHRDLKPENLLFDSDKKNANLKVIDFGTSRKYDKA-------KKMSKRL--GTP-----YYIAPEVLDQN- . .. | ... || . | |..|..|||| | | .... |. ||| ||. . . .|. |. |||... . HRPKLCMKDLLSFCWQIACGMEYLHSKNCIHRDLAARNCLVGENH---TVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGKTMLPIRWMAPECINYGK YDEKCDVWSCGVILY-ILLCGYPPFGG-----RSEDEILKKVRLGKFKFEPED-----WDRISEEAKNLIKKMLTYDPKKRISAEQALNDA . .| |||| || .. |. | .| | | .|....|. |. |.. . ..| ...|. .||..| . .. . FTTKSDVWSFGVCMWEIFTYGQQPYPGMIQQMMSNQEVIEYVKQGYRMPQPPNDYPMSFVCCPDEMYQIMKQCWHEDPEDRPTFSEIHECF |
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Kinase | 5812.AA | Pkinase_Tyr | 272-395 | 31 | 8.1e-21 | 71.13 | Pfam | 1-137 (270) | Show / Hide |
Range on Protein: 272-395 Range on HMM: 1-137/270 Sequence Identity: 31% (43 aa) YKIGEVLGEGAFGQVSKVVHK----STGMIRAMKTIKKSSIIKEE--EDRLFSEMNILKNL-DHPNILRLIELFQ-DNKN--YYLVTEYCSGGELFDKIK ..|..|||||||.| | . | .|.. | |.. | . .|. . ...|..|.|.| .||||.||. . . .|.|.||. .| | | . ITFGKKLGEGAFGEVYKGTWKGDPDNTKIPVAVKML-KEGAMHEQNCREDFMREAKIMKQLGHHPNIVRLYGVCTDQGEPNQIYIVMEYMPHGDLLDYLR SM----THFTEKMAADYMKQILSAVVYCHQNNIVHRDL . ..| |. .. || .. | ...|..|||| KHREDKQPLTMKDLLQMCWQIAKGMEYLESKNCIHRDL |
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Kinase | 5812.AA | Pkinase_Tyr | 439-483 | 30 | 4.503912 | 0.87 | Pfam | 182-230 (270) | Show / Hide |
Range on Protein: 439-483 Range on HMM: 182-230/270 Sequence Identity: 30% (15 aa) APEVLDQN-YDEKCDVWSCGVILYILLC-GYPP-FGGRSEDEILKKV-R |||.. . . .| |||| || .. .. | | . | | |..... . APECINYGKFTTKSDVWSFGVLMWEIFTYGEQPTYPGMSNEEVYEYIYE |
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EFh | 5812.AA | EFh | 574-602 | 37 | 5.4e-08 | 33.79 | SMART | 1-29 (29) | Show / Hide |
Range on Protein: 574-602 Range on HMM: 1-29/29 Sequence Identity: 37% (11 aa) ELQKTFRSLDKNGDGTLSKEELIDGYTTV |... || .||.|||....||..|. ... EFKEMFRMFDKDGDGYIDFEEFKDMMKSL |
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Efhand | 5812.AA | efhand | 574-602 | 34 | 3.9e-07 | 30.55 | Pfam | 1-29 (29) | Show / Hide |
Range on Protein: 574-602 Range on HMM: 1-29/29 Sequence Identity: 34% (10 aa) ELQKTFRSLDKNGDGTLSKEELIDGYTTV ||.. |. .||.|||....||........ ELKEMFKEFDKDGDGYIDFEEFCEMMKKL |
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EFh | 5812.AA | EFh | 612-640 | 20 | 3e-06 | 27.84 | SMART | 1-29 (29) | Show / Hide |
Range on Protein: 612-640 Range on HMM: 1-29/29 Sequence Identity: 20% (6 aa) QVDRILDEVDINKSGKVDFTEFLMAASNK ..... ...| ...|..|| ||... ... EFKEMFRMFDKDGDGYIDFEEFKDMMKSL |
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Efhand | 5812.AA | efhand | 612-640 | 24 | 6e-06 | 26.13 | Pfam | 1-29 (29) | Show / Hide |
Range on Protein: 612-640 Range on HMM: 1-29/29 Sequence Identity: 24% (7 aa) QVDRILDEVDINKSGKVDFTEFLMAASNK ..... .|.| ...|..|| ||. . ... ELKEMFKEFDKDGDGYIDFEEFCEMMKKL |
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EFh | 5812.AA | EFh | 648-676 | 31 | 9e-07 | 29.74 | SMART | 1-29 (29) | Show / Hide |
Range on Protein: 648-676 Range on HMM: 1-29/29 Sequence Identity: 31% (9 aa) KVEQSFKIFDQDGNGNITKDELQYIMGDI .... |..||.||.| |...|.. .| . EFKEMFRMFDKDGDGYIDFEEFKDMMKSL |
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Efhand | 5812.AA | efhand | 648-676 | 34 | 2e-06 | 28.38 | Pfam | 1-29 (29) | Show / Hide |
Range on Protein: 648-676 Range on HMM: 1-29/29 Sequence Identity: 34% (10 aa) KVEQSFKIFDQDGNGNITKDELQYIMGDI .... ||.||.||.| |...|.. .| .. ELKEMFKEFDKDGDGYIDFEEFCEMMKKL |
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Efhand | 5812.AA | efhand | 680-708 | 27 | 9e-06 | 25.55 | Pfam | 1-29 (29) | Show / Hide |
Range on Protein: 680-708 Range on HMM: 1-29/29 Sequence Identity: 27% (8 aa) FWKQILDECDTNKDGMISQTEFLDLLINK .|.. .| |...|| |. ||.... .. ELKEMFKEFDKDGDGYIDFEEFCEMMKKL |
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EFh | 5812.AA | EFh | 680-708 | 27 | 4.1e-05 | 24.23 | SMART | 1-29 (29) | Show / Hide |
Range on Protein: 680-708 Range on HMM: 1-29/29 Sequence Identity: 27% (8 aa) FWKQILDECDTNKDGMISQTEFLDLLINK .|.. .. |...|| |. ||.|.. .. EFKEMFRMFDKDGDGYIDFEEFKDMMKSL |