Gene 7386 (Tetrahymena)
7386
Sequence
Protein domains of 7386.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.
Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.
| Domain | Protein name | Domain Name | Range | Identity (%) | Significance | Score | Profile Source | Profile Range (length) | Alignment |
|---|---|---|---|---|---|---|---|---|---|
| Kinase | 7386.AA | CDPK | 38-295 | 52 | 2.7e-195 | 604.15 | In-house | 1-271 (271) | Show / Hide |
Range on Protein: 38-295 Range on HMM: 1-271/271 Sequence Identity: 52% (141 aa) YTFSSVLGKGGFGTVKLAALKNGVSDKKVAVKIIEKNRLKNKQ--YILLRELEILRSLDHPNIIKFYEVYQDEMFFYICME--YCAGGELLDRITKARNF |....|||||.||.|... .|.. ....||.|||.|.|.|.|. .....|.|||..||||||||.||.||||...||.|| ||.||||.|.|. ..| YKIKKVLGKGHFGQVRKVKHKQKTNQERVAMKIIPKSRVKDKEQQQQFFNEIEILKQLDHPNIIKIYEFYQDEKNYYIVMETEYCTGGELFDYIIEKGHF REQDAALIMDKVFSAINHMHSRGIVHRDIKPENILFVSKSPDS----EIKIIDFGLSVKCDG-----MKDLSTMVGTPLYVSPNVLRGRYDSSSDNWSAG |..||.||....||.|..||..|||||.||||||| ||..|| .||.||.|.| |.|. .|..|...|||.|..|.||...|. ..|.||.| TEKEAAYIMRQILSAVNYCHSNNIVHRDLKPENILFDSKKDDSWVIYNIKVIDWGTSKKFDQNQKIEDKKMSQRCGTPYYIAPEVLQKKYNEKCDIWSCG VILYVLLVGYPPFYGKSRGEVFRKIEKGVYNMEGKEWDTVSSEAKDLVRKLLVVDSNKRMTAAQALKHKWI ||||.||.||||||||.. |.. |..||.|..||.||| .|.|||||.||.|..|..|||.|.|||.|.|. VILYILLCGYPPFYGKNDQEIMEKVKKGKYSFEGPEWDHISDEAKDLIRKMLCYDPKKRMSAQQALQHPWF |
|||||||||
| Kinase | 7386.AA | CAMK1 | 38-295 | 44 | 1.7e-161 | 473.24 | In-house | 1-276 (276) | Show / Hide |
Range on Protein: 38-295 Range on HMM: 1-276/276 Sequence Identity: 44% (124 aa) YTFSSVLGKGGFGTVKLAALKNGV-SDKKVAVKIIE-KNRLKNKQ----YILLRELEILRS---LDHPNIIKFYEVYQDEMFFYICMEYCAGGELLDRIT | | ...|.| |..|.|. |. .|..|.|.|. | .|.| . |..|.||... .||||||||||.|.....||..||.. ||||.||| YEFGKEIGRGAFSEVYLCTHKETQTNGKQYAIKCIDKKKFMKKKDMQKQEALENEIEIMKKVSKIDHPNIIKFYEWYESDNHFYLVMELVTGGELFDRIV KARNFREQDAALIMDKVFSAINHMHSRGIVHRDIKPENILFVSKSPDSEIK--IIDFGLSVKCDGMKD-LSTMVGTPLYVSPNVLRG----RYDSSSDNW . |. |.||..|| ...||...|||.||||||.||||.|...|..||.|| |.||||| ..|. . ..|..||| || |.|| . || . | | EKGNYTEKDARHIMKQILSAVEYMHSKGIVHRDLKPENLLYYDKDEDSKIKRSIADFGLSKIFDHDENLMKTACGTPGYVAPEVLECKKDKPYDKACDMW SAGVILYVLLVGYPPFYGKS-RGEVFRKIEKGVYNMEGKEWDTVSSE-AKDLVRKLLVVDSNKRMTAAQALKHKWI |.|||.|.||.||||||... | |.|| |. |.. ..|| .|.. |||.....|.|| .|| |..|.|.|.|| SIGVITYILLCGYPPFYDENVDNELFEKIKKCEYEFPSPWWDNISDQEAKDFIKHMLEVDPKKRYTCEQCLNHPWI |
|||||||||
| Kinase | 7386.AA | CAMK | 43-295 | 30 | 2.2e-127 | 412.78 | In-house | 1-425 (425) | Show / Hide |
Range on Protein: 43-295
Range on HMM: 1-425/425
Sequence Identity: 30% (128 aa)
VLGKGGFGTVKLAALK-NG-VSD--------KKVAVKIIEKNRLKN---------------------------KQYILLRELEILRS-------LDHPNI
.||.|.||.|||. | .. . .|||.|||.|..||. .. ..||.||... ||||||
TLGRGSFGKVKLCIHKNTTGKERVHHIYTNGQKVAIKIIDKKKLKDKQNQDYSNCYKIDKSKCKHRYCWRRPKDRKNVRREIEIMKKLQGIGNKLDHPNI
IKFYEVYQD-------------------EMFFYICM---EYCAGGEL----LDRITKARN---------------FREQDAALIMDKVFSAINHMHSRGI
||.||||.| ....|. | ||| |||| .|.|.. .. | |..|. .. . ||....||..|
IKLYEVYEDPHYFKNTNDYETSKQVFTKDKHMYMVMEIMEYCSGGELFDDLFDYIVEHGCYGEEFDQFDIVERGRFTEREARRYFRQICSAVHYCHSHNI
VHRDIKPENILFVSKSPDSE--------------IKIIDFGLSVKCDG------------------------MKDLSTMVGTPLYVS-PNVLRGR-----
||||.||||||......||. |||||||.. |.|. . ..|..||| |.. | ||.|
VHRDLKPENILLDDNNDDSDPVEHDEIFDWNNNNIKIIDFGFANKFDPGENNFMCSDYKGGEMHNQWTTPTEGQKMKTFCGTPEYMAAPEVLNGKGHCNM
----------YDSSSDNWSAGVILYVLLVGYPPFYGK-------------SRGEVFRKIEKGVYNMEGKE------------WDTVSSE--------AKD
|. ..| ||.|||||..|.|||||||. . | |.|| || |... .. || .| | .||
QNATDEEKPYYGPKCDMWSCGVILYIMLCGYPPFYGDCDNEICEDEWIGMNDYELFEKIMKGKYDFPPPYFSPISCNYGPEWWDDISDEFHHFVSQECKD
LVRKLLVVDSNKRMTAAQALKHKWI
|.||.|.|| .||||..|.|.|.|.
LIRKMLQVDPEKRMTIEQCLNHPWM
|
|||||||||
| Kinase | 7386.AA | Ciliate-E2a | 38-295 | 42 | 3e-124 | 367.61 | In-house | 1-275 (275) | Show / Hide |
Range on Protein: 38-295 Range on HMM: 1-275/275 Sequence Identity: 42% (117 aa) YTFSSVLGKGGFGTVKLAALKNGVSDKKVAVKIIEKNRLKN-KQYILLRELEILRSLDHPNIIKFYEVYQDEMFFYICMEYCAGGELLDRITKAR-NFRE | | ..||| || |.|| .|. ......|.| |.. . .. . .|. |.|.||||||||.||||.|| .|. |||| ||||.|.| . .| | YKFIKKIGKGNFGSVYLAQHKQT-GKQFAMKKFIKKMYQQKKGKEYFMNEINIMRQLDHPNIIKLYEVYEDENNYYLVMEYCEGGELYDKIKQCKRFFEE -QDAALIMDKVFS-AINHMHSRGIVHRDIKPENILFV---SKS-PDSEIKIIDFGLSVKCDGMKD--LSTMVGTPLYVS------PNVLRGR-YDSSSDN |... || . .. ....||.|.|.|||.||||||| ..| ..|.||||||||. ..|. . . ...||| || . || .. || . | IQEICDIMQQLLWQGLHYMHQRNIMHRDLKPENILFKNCSKNSIQNSDIKIIDFGLATFIDKDEKKYMFQKCGTPGYVAPEVLNNKEVLKHKQYDTKCDM WSAGVILYVLLVGYPPFYGKSRGEVFRKIEKGVYNMEGKE-WDTVSSEAKDLVRKLLVVDSNKRMTAAQALKHKWI ||.|||.| ||.|.|||.||. |.. ...| .. ...| | .|.|.|||..|.|..| .|| ||.|||.|.| WSCGVIFYILLCGKPPFKGKTYNEILQQNKKCKIDFNCPECWEKCSKECKDLMKKMLEKDPKKRITAQQALNHPWF |
|||||||||
| Kinase | 7386.AA | S_TKc | 38-295 | 37 | 3.8e-99 | 336.62 | SMART | 1-231 (231) | Show / Hide |
Range on Protein: 38-295 Range on HMM: 1-231/231 Sequence Identity: 37% (104 aa) YTFSSVLGKGGFGTVKLAALKNGVSDKKVAVKIIEKNRLKNKQYILLRELEILRSLDHPNIIKFYEVYQDEMFFYICMEYCAG--GELLDRITKARN--- |.. ..|||.||.|... |. ....||.||| ..||..||.. .||||.|.|.|.|| ..|..|||| | |.|.|.| | . YEILRKIGKGAFGKVYKCRHKK--TGRIVAIKIIK--------EHIRREIQILKK-HHPNIVKLYDVFQD-DHLYMVMEYCDGDLGDLFDYIKKRGRHGL ---FREQDAALIMDKVFSAINHMHSRGIVHRDIKPENILFVSKSPDSEIKIIDFGLSVKCDGMKDLSTMVGTPLYVSPNVLRGRYDS-SSDNWSAGVILY | | .|. .| ...|....||.||.|||.||||||. . .|||.||||. . .|..||| |..| || |. ..| || |.||| RFPFPE-HARFYMYQICCALEYCHSHGIIHRDLKPENILLDE-----HIKICDFGLARQL------TTFCGTPWYMAPEVL--GYGKCKCDWWSCGCILY VLLVGYPPFYGKSRGEVFRKIEKGVYNMEGKEWDTVSSEAKDLVRKLLVVDSNKRMTAAQALK-------HKWI .|.|||||. ..|.|| |.||||..||.|..| .||.|| .||. | |. EMLCGYPPFP--QMQMMFKKIG--------------SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF |
|||||||||
| Kinase | 7386.AA | CAMK-Unique | 38-295 | 29 | 6.7e-98 | 323.79 | In-house | 1-363 (363) | Show / Hide |
Range on Protein: 38-295
Range on HMM: 1-363/363
Sequence Identity: 29% (109 aa)
YTFSSVLGKGGFGTVKLAALKNGVSDKKVAVKIIEKNRLK-NKQYI------------------LLRELEILRSLDHPNIIKFYEV----YQDEM-----
|.. ..|.|.|| |. . .. . || |.|...| . . .||.. | ||..|....|||||||.|.. ..|.
YKMHRIIGHGNFGHVYEC--MDRETGKKWACKMVKKQTHGNKKQKQQRNFDLRYKITEKRRDMKLKREHQIWKMVDHPNIIKLYDWNNPIFCDRKYPLCD
----------FFYICMEYCAGGELLDRITK--------------------ARNFRE--QDAALIMDKVFSAINHMHSRGIVHRDIKPENILFVSKSP---
.|| |||| ||.|.| | | . | | |...|| .. ||...||| .|||||.|.|||.. . .
LIIKTPRALPYMYIVMEYCQGGDLFDWIQKWDEFYFNFIIKFDFNILKRCQGHFSERCWDTCFIMQCLLSAVAYMHSQDIVHRDLKLENIMVCYSFKDNN
----------DSEIKIIDFGLSVKCDGMKDLS---TMVGTPLYVSP--------------NVLR-GRYDSSS----DNWSAGVILYVLLVGYPPFYGKSR
.. ||..||||... .. | . ||.|||.|..| |. .||. . | || |||.| .|.|.|||.. .
HHRDFPYDWSNWHIKLCDFGLCCHYNHNKMCHMMQTMCGTPCYMAPEIVFCKNYQEMTRDEVINMQCYDQQCSPASDIWSLGVIMYYMLCGCPPFDCECE
G--------EVFRKIEKGVY-NMEGKEWDT---VSSEAKDLVRKLLVVDSNKRMTAAQALKHKWI
| |..| || | | . | |. .| ||||.| ....|| ..| .|...|.| ||
DRDYENHDKEIFECICKGDYCNFDWKMWHGPDYISQEAKDFVKCCMTVDPDHRWSAKELLEHQWI
|
|||||||||
| Kinase | 7386.AA | RSK | 41-295 | 34 | 8.3e-95 | 321.27 | In-house | 1-278 (278) | Show / Hide |
Range on Protein: 41-295 Range on HMM: 1-278/278 Sequence Identity: 34% (95 aa) SSVLGKGGFGTVKLAALKNGVSDKKV-AVKIIEKNRLKNKQY---ILLRELEILRSLD-HPNIIKFYEVYQDEMFFYICMEYCAGGELLDRITKARN--- .|||.||.| | | ... ... |.|...|. ....| ..| .|| ||.|.. ....|.| .|..|||| ||||.... | . LKVLGQGGYGKVFLCRKCTHHDTGQIYAMKVLKKAKIVQRQKDTRHTMTERNILERCQQHPFIVTLHYAFQTEGKLYLIMEYCRGGELFTHLQKEKHFGC FREQDAALIMDKVFSAINHMHSRGIVHRDIKPENILFVSKSPD-SEIKIIDFGLSVK--CDGMKDLSTMVGTPLYVSPNVLR----GR-YDSSSDNWSAG | | .|. .| .. .|. |.|..||.|||.||||||. ..| . .||..|||.. . || . . | ..| |. | .|. .. .| . | || | FSEDEACFYMAEIVLAVEHLHQQGIIHRDLKPENILYDDES-NEGHIKLTDFGFCKQFRCDHNQWTMTFCYTIEYMAPEMLKRANQQGGHDKACDWWSLG VILYVLLVGYPPFYG---KSRGEVFRKIEKGVYNMEGKEWDTVSSEAKDLVRKLLVVDSNKRMT-----AAQALKHKWI |..| .|.|.|||.| ..| |....|.|| .......|...| |||||.||.| .| .|| . |.. ..|.|. VLMYEMLTGCPPFQGPNDNNRKEIMKRIQKGKFSLTMPNWQYLSQEAKDLIRKMLHRDPHKRLGCGPQDAEEIKQHPWF |
|||||||||
| Kinase | 7386.AA | CAMKL | 38-295 | 37 | 3.3e-94 | 301.05 | In-house | 1-297 (297) | Show / Hide |
Range on Protein: 38-295 Range on HMM: 1-297/297 Sequence Identity: 37% (114 aa) YTFSSVLGKGGFGTVKLAAL-KNGVSDKKVAVKIIEKNRLKNKQYIL--------------LRELEILRSLD---HPNIIKFYEVYQDEMF------FYI |.. .||||.||.|||| .. .|||.|||.|....|..... || .|...|. ||||||.|||.... . .|. YRIGKTLGKGSFGKVKLATHIRTT--GEKVAIKIIDKKKIWNDPWMKKNKCGQKHESDMRIRREIQIMKMLNIGKHPNIIKLYEVIETPEHDIETKKIYL CMEYCAGGE--LLDRITKARN----FREQDAALIMDKVFSAINHMHSRGIVHRDIKPENILFVSKSPDSEIKIIDFGLSVK---C-DGMKD-LSTMVGTP |||| ||| |.|.| | .. . | .| . . ||.|..||.|||||||||||||. .. |||||||.| . | .| . |.| |.| VMEYCSGGEMDLFDYIVKHGHRRGRMPEHEARRYFRQIVSAVNYCHSHGIVHRDIKPENILLDENGNN-NIKIIDFGFSNMYRPCIFGPGQKLKTFCGSP LYVSPNVLRG--R-YD-SSSDNWSAGVILYVLLVGYPPFYGK--------SRGEVFRKIEKGVYNMEGKEWDTVSSEAKDLVRKLLVVDSNKRMTAAQAL | .| .. | . || | ||.|||||....|| || . . ..|| .| |.. | || ...|| ||.|.|. .||.|. | . PYMAPEIFQGNNKPYDGPKVDIWSCGVILYAMVCGYLPFDDDTYNKQGKDNI-YLYWKIMCG-YYP--PIWYHVS-DCRDLIRKMLQVNPEKRPTIHQIM KHKWI .|.| NHPWM |
|||||||||
| Kinase | 7386.AA | Ciliate-E2 | 38-295 | 28 | 1.6e-93 | 317.05 | In-house | 1-365 (365) | Show / Hide |
Range on Protein: 38-295 Range on HMM: 1-365/365 Sequence Identity: 28% (110 aa) YTFSSVLGKGGFGTVKLAALKN---------------------GVSDKKVAVKIIEKN--RLKNKQYILLRELE----------ILRSLDHPNIIKFYEV | | ..|.|.||.|... .. .| |..|.||..|| . ... ..||.. ||..|.||||||.||. YKFIKKIGQGNFGSVYKCKVWKVQKQFAIKIIDQKQQRQQMQEKVKIKIYAMKIMKKNQIEQIKQEIHIMREINCFYKKINEKNILEQLNHPNIIKMYEC YQ--DEMFFYICMEYCAGGELLDRITKARNFR-----------EQDAALIMDKVFS---------------AINHMHSRG-IVHRDIKPENILFVSKSPD .| |. .|. |||| ||.|.|.| . . .| |. .. || .... |....||.. |.||||||||||| FQEKDDNNIYLVMEYCQGGDLFDYIKNNKKKRNHEIEKDKYFTEKEIKYIMKQILQGFKTKAEFYIACIILALEYLHSKNNIIHRDIKPENILF------ SEIKIIDFGLSVKCD-------------GMKDLS--------------------TMVGTPLYVSPNVLRGR----------YDSSSDNWSAGVILYVLLV ||||||||| |.| ... . | .||| |..| .|.| || ..| ||.||||| .| --IKIIDFGLSKKYDDDNQNRTHKQQCKWYMF-KNDTSRTPGYMDQIIQQNMFNTICGTPGYMAPEILNGKKYDNQQKQKGYDYKCDIWSLGVILYEMLF GYPPFYGKSRGEVFRKIEKGVYNMEGKE--------------WDTVSSEAKDLVRK----LLVVDSNKRMT-AAQALKHKWI |.||| ...|... .. .| |. .| |.||| .| .|..| .||.| . |.|.|.|. GKPPF--------QQQIKQCKIDFPCPEWQKDTQCIQCKWKSWKKWSQECKDLIKKFGKRMLQKDPEKRITGWEQILNHPWF |
|||||||||
| Kinase | 7386.AA | Pkinase | 38-295 | 32 | 1.8e-91 | 315.0 | Pfam | 1-293 (293) | Show / Hide |
Range on Protein: 38-295 Range on HMM: 1-293/293 Sequence Identity: 32% (96 aa) YTFSSVLGKGGFGTVKLAALKNGVSDKKVAVKIIEKNRLKNKQ-YILLR--ELEILRSLDHPNIIKFYEVYQDEMFFYICMEYCAGG----ELLDRIT-- |.. ...|.|.||.|... |. .||||||.| . | .. ....| |..|...|.||||...|....|. |..|||| || .| |.|. YHIGRKIGSGSFGCVYKCHHKGTGK--IVAVKIIKKRHEKSWKDQTHRRLSEIQIMKRLNHPNIVRLYDWFEDKDHIYMVMEYCEGGLYVMDLFDYISTW KARNF--REQDAALIMDKVFSAINHMHSRGIVHRDIKPENILFV-SKSPDSEIKIIDFGLSVK--CDGMKDLSTMVGTPLYVSPNVLR--GRYDSSSDNW . ..| |... .| ........||.||.|||.||||||.. .|. .||.||||. . ..| .||| |..| |.| |....| | RHGCFYFSEWECKFYMYQILRGLEYCHSMGIIHRDLKPENILIDNNGHIDACVKICDFGLAKQFDY-NNS-MTTFCGTPWYMAPEVIRGGQYYGPKVDMW SAGVILYVLLVGYPPFYGK------SRGEVFRKIEKGVYNMEGKEWDTVS-----------------SEAKDLVRKLLVVDSNKRMTAAQALKHKWI |.|.||| .| |.|||.|. . .....| .. . . .|...| .|.||.....| .| .|| ||.|.|.|.|. SCGCILYEMLCGRPPFPGHCWHDNHDQMQMICRIMGPPLHFDWPWWCSISYFFFRHWHFHWTFHNWSEECKDFIKWCLCKDPKKRPTAEQILQHPWF |
|||||||||
| Kinase | 7386.AA | DCAMKL | 38-295 | 36 | 1.9e-91 | 284.71 | In-house | 1-279 (279) | Show / Hide |
Range on Protein: 38-295 Range on HMM: 1-279/279 Sequence Identity: 36% (103 aa) YTFSSVLGKGGFGTVKLAALKNGVSDKKVAVKI-----------------IEKNRLKNKQYILLRELEILRSLDHPNIIKFYEVYQDEMFFYICMEYCAG | . |.| | .|... . |.| | || |.|...|.| . |..|.....||.||. ||.. |. |. ||| | YQIGRIIGDGNFAVVHECRHRETG-DHKYAMKIRYQSTLQFSFPSKFFQQIDKRKCKGKEHMIDNEVSIMQKIKHPHIIQLYEHWDTETHYYLVMEYVQG GELLDRITKARNFREQDAALIMDKVFSAINHMHSRGIVHRDIKPENILFVS-KSPDSEIKIIDFGLSVKCDG-MKDLSTMVGTPLYVSPNVLRGR-YDSS | | | ||. . | | |||..| ....|....|...|||||||||| | . . ..| |||| .| . |.| ||| || | .|. | GDLFDAITENTKFTERDAAIMMTCLCKALKYLHEMNIVHRDIKPENLLVCKHEDGEKSLKLCDFGLACHVNGDFGPLYTVCGTPTYVAPEILMETGYGCK SDNWSAGVILYVLLVGYPPFYGK--SRGEVFRKIEKGVYNMEGKEWDTVSSEAKDLVRKLLVVDSNKRMTAAQALKHKWI | |.||||||.||.|.||| . . | | .| | .. .|| .|. ||||....|.|| || || | ..| |. VDIWAAGVILYILLCGFPPFRSPDNDQEELFDQIMQGKFEFPMPYWDNISDSAKDLISHMLQVDPEKRYTAEQIMQHPWV |
|||||||||
| Kinase | 7386.AA | RSK | 38-295 | 35 | 4.7e-80 | 272.27 | In-house | 1-271 (271) | Show / Hide |
Range on Protein: 38-295 Range on HMM: 1-271/271 Sequence Identity: 35% (96 aa) YTFSSVLGKGGFG---TVKLAALKNGVSDKKVAVKIIEKNRLKNK-QYILLRELEILRSLDHPNIIKFYEVYQDEMFFYICMEYCAGGELLDRITKARNF | . ...|.| |. .| | .... |.|||.|. ...| . | ||| .||.|.| ..|.||| |. |. ..||.|.||. | . | YELHECIGQGSFSKVYVCKKCQHKD--TNQHYAMKIIKKATRDVKDRVCWEEERIILRYGHHPFIVKLHYVFQDEGKVYMIMDFMRGGDLFDRLLKQKMF REQDAALIMDKVFSAINHMHSRGIVHRDIKPENILFVSK--SPDSEIKIIDFGLSVKCDGMKD-LSTMVGTPLYVSPNVLRGR-YDSSSDNWSAGVILYV |.... .| ...| .. || |||||| ||||||.... .|.. ||| |||.. . . | | .| |. | ||. . .| ..| || ||..| SEREVKFYMAEIALAMEYLHSQGIVHRDLKPENILYDDESGNPGH-IKICDFGFAKQLRDENGMLMTFCYTANYMAPEVLKRQGHDQACDWWSFGVLMYE LLVGYPPFYGKSRGEVFRKIEK---GVYNMEGKEWDTVSSEAKDLVRKLLVVDSNKRMTA-----AQALKHKWI | |..||..| | . . .| . | . | . ||..| |||||.|..| .| ..| .| .|...|.|. MLTGCTPFQNKPRDTPMNIIQRIKLGMFSMTHGNWDFISDEAKDLLRMMLHRDPHNRLGAGPNGVEQIKQHPWF |
|||||||||
| Kinase | 7386.AA | Pkinase_Tyr | 38-162 | 28 | 2.3e-17 | 59.42 | Pfam | 1-137 (270) | Show / Hide |
Range on Protein: 38-162 Range on HMM: 1-137/270 Sequence Identity: 28% (40 aa) YTFSSVLGKGGFGTVKLAALK--NGVSDKKVAVKIIEKNRLKNKQ---YILLRELEILRSL-DHPNIIKFYEVYQ-DEMF--FYICMEYCAGGELLDRIT || .||.| ||.|... .| . . .||||.. |. .| ..||..|...| .||||...| | .. || |||...| ||| ITFGKKLGEGAFGEVYKGTWKGDPDNTKIPVAVKML-KEGAMHEQNCREDFMREAKIMKQLGHHPNIVRLYGVCTDQGEPNQIYIVMEYMPHGDLLDYLR K----ARNFREQDAALIMDKVFSAINHMHSRGIVHRDI | ... .| . . .. .. .|....|||. KHREDKQPLTMKDLLQMCWQIAKGMEYLESKNCIHRDL |
|||||||||
| Kinase | 7386.AA | TyrKc | 38-295 | 23 | 6.9e-16 | 34.14 | SMART | 1-280 (280) | Show / Hide |
Range on Protein: 38-295 Range on HMM: 1-280/280 Sequence Identity: 23% (68 aa) YTFSSVLGKGGFGTVKLAALKNGVSDKKVAVKIIEKNRLKNKQYILLRELEILRSL--DHPNIIKFYEVYQDE-------MFFYICMEYCAGGELLDRIT |. .|| | ||.| .. .| .|||| . .. . ..||..|...| .||||...| | .. .| |||...| |.|.. ITLGKKLGEGAFGEVYKGTWK-----IQVAVKMLKEDA----REDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPHGDLKDYLR KARN-FREQDAALIMDKVFSAINHMHSRGIVHRDIKPENILFVSKSPDSEIKIIDFGLSVKCDGM-------KDLSTMV--GTP--L---YVSPNVL-RG | |. . .| .. . . .. ||....|||. |.| .. .|| ||||| . . . ... |. | .| .. | KHRPKLCMKDLLSFCWQIACGMEYLHSKNCIHRDLAARNCLVGENH---TVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGKTMLPIRWMAPECINYG RYDSSSDNWSAGVILY-VLLVGYPPFYG-----KSRGEVFRKIEKGVYNMEGKE-----WDTVSSEAKDLVRKLLVVDSNKRMTAAQALKHKWI .. . || || || .. .. | .| .| .| ||......| . . .. . ..| .. .. | ..| | .. |. . KFTTKSDVWSFGVCMWEIFTYGQQPYPGMIQQMMSNQEVIEYVKQGYRMPQPPNDYPMSFVCCPDEMYQIMKQCWHEDPEDRPTFSEI--HECF |
|||||||||
| Efhand | 7386.AA | efhand | 355-383 | 31 | 0.000741 | 18.53 | Pfam | 1-29 (29) | Show / Hide |
Range on Protein: 355-383 Range on HMM: 1-29/29 Sequence Identity: 31% (9 aa) QLKFAFKQMDTEQTGEIGIDQLKEVMEQN .|| .||..|. . |.| .. ..|.|.. ELKEMFKEFDKDGDGYIDFEEFCEMMKKL |
|||||||||
| EFh | 7386.AA | EFh | 355-383 | 24 | 0.017225 | 10.72 | SMART | 1-29 (29) | Show / Hide |
Range on Protein: 355-383 Range on HMM: 1-29/29 Sequence Identity: 24% (7 aa) QLKFAFKQMDTEQTGEIGIDQLKEVMEQN ..| .|. .|. |.| . .|..| EFKEMFRMFDKDGDGYIDFEEFKDMMKSL |
|||||||||
| Efhand | 7386.AA | efhand | 430-458 | 20 | 0.052427 | 11.76 | Pfam | 1-29 (29) | Show / Hide |
Range on Protein: 430-458 Range on HMM: 1-29/29 Sequence Identity: 20% (6 aa) KIWSLFKYFDPSNSNFITIQDLKEIFLRN .. .|| || .. .|......|.. . ELKEMFKEFDKDGDGYIDFEEFCEMMKKL |
|||||||||
| Efhand | 7386.AA | efhand | 466-494 | 51 | 2e-08 | 35.29 | Pfam | 1-29 (29) | Show / Hide |
Range on Protein: 466-494 Range on HMM: 1-29/29 Sequence Identity: 51% (15 aa) ELKQMVKEVDPNNDGKISLEEFKLLMKGE |||.| ||.| ..||.|..|||. .|| ELKEMFKEFDKDGDGYIDFEEFCEMMKKL |
|||||||||
| EFh | 7386.AA | EFh | 466-494 | 44 | 3.8e-07 | 31.0 | SMART | 1-29 (29) | Show / Hide |
Range on Protein: 466-494 Range on HMM: 1-29/29 Sequence Identity: 44% (13 aa) ELKQMVKEVDPNNDGKISLEEFKLLMKGE |.|.| ...| ..||.|..|||| .|| EFKEMFRMFDKDGDGYIDFEEFKDMMKSL |
|||||||||