Gene 10222 (Tetrahymena)

10222

Species: Tetrahymena
Alias: 964, 5.m00573, 3828.m01486, PreTt10222, TTHERM_00079770, 10222
External Links: Tetrahymena Genome Database (TGD)
Annotation:

Classification

Group: CK1
Family: CK1
Subfamily: CK1-Unclassified

Sequence

Name Sequence Type Origin Length Description Download
10222.AA Protein None 383 None Fasta, JSON
10222.kin_dom Protein Kinase Domain None 244 None Fasta, JSON
10222.NA RNA None 1152 None Fasta, JSON

Protein domain

Protein domains of 10222.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Kinase 10222.AA CK1-Unclassified 14-250 64 1.1e-201 600.95 In-house 1-244 (244) Show / Hide 
Range on Protein: 14-250
Range on HMM: 1-244/244
Sequence Identity: 64% (159 aa)

FKLTKKVSQGAFGEVFHGINLNTNMEVAVKLEPAKTKHPQLFFEVKLYQYLQRDANVAD---KGIPNVYYAATE--REYNIMVMDLLGPSLEDLFNMCNR
.....|. ||.|||....||..||.|||.||| ...|||||..|.|..||||...|. |   ||||..|. ..|  ..||||||||||||||||||||||
YRVIEKIGQGSFGEIYKCINMQTNEEVAIKLEKKNSKHPQLCYEAKIMQYLQNGHNC-DNFIKGIPKMYWCGQEEQGDYNIMVMDLLGPSLEDLFNMCNR

KFTVKTTLMLADQLIQRVSYVHSKHFLHRDIKPDNFLIG-TGKNAYKVFIIDFGLAKRYL--KKDGKHIEYKEGKSLTGTARYASLNTHLGIEQGRRDDL
||..||.||.|||.|||. |.|.|.|.||||||||||.| .|||...|.||||||.|||.  .|.||||.|.|.|.|||||||||.|.||||||.|||||
KFSLKTVLMIADQMIQRIEYLHNKNFIHRDIKPDNFLMGKLGKNHHQVYIIDFGLSKRYIDMDKTGKHIPYRENKNLTGTARYASINAHLGIEQSRRDDL

ESLGYMFMYFLRGSLPWQNLKATNKKDKYEKIMEKKLQTQVEELC
||||| ..|||.|||||||.|| |||.|||||||.|..| ||.||
ESLGYVLIYFLKGSLPWQNIKANNKKEKYEKIMEMKMSTPVEQLC
Kinase 10222.AA CK1 14-276 63 2.3e-197 661.96 In-house 1-271 (271) Show / Hide 
Range on Protein: 14-276
Range on HMM: 1-271/271
Sequence Identity: 63% (175 aa)

FKLTKKVSQGAFGEVFHGINLNTNME---VAVKLEPAKTKHPQLFFEVKLYQYLQRDANVAD---KGIPNVYYAATE--REYNIMVMDLLGPSLEDLFNM
.....|. ||.||....|||. ||.|   ||.|||..|.||||| .|.|.|..||.. |. |   .|||..|. ..|  ..||||||||||||||||||.
YRVGRKIGQGSFGDIYLGINM-TNGEENHVAIKLEKNKSKHPQLHYEAKIYKILQGH-NC-DNQCHGIPHMYWCGQEEQGDYNIMVMDLLGPSLEDLFNF

CNRKFTVKTTLMLADQLIQRVSYVHSKHFLHRDIKPDNFLIGT-GKNAYKVFIIDFGLAKRYLK-KDGKHIEYKEGKSLTGTARYASLNTHLGIEQGRRD
|||||..||.||.|||.|||. |||.|.|.||||||||||.|. ||.. .|.||||||||||.. |...||.|.|.|.|||||||||.||||||||.|||
CNRKFSLKTVLMIADQMIQRIEYVHNKNFIHRDIKPDNFLMGRYGKHCHQVYIIDFGLAKRYRDDKTHQHIPYRENKNLTGTARYASINTHLGIEQSRRD

DLESLGYMFMYFLRGSLPWQNLKATNKKDKYEKIMEKKLQTQVEELCKG-FPSEFATYLAYTKNLRFDEKPDYE
|.|||||..|||||||||||.||| .||.|||||||||..| ||.|||| ||.|||.|| |...|.|.|||||.
DMESLGYVLMYFLRGSLPWQGLKANTKKQKYEKIMEKKMSTPVEQLCKGNFPNEFAMYLNYCRQLHFEEKPDYM
Kinase 10222.AA CK1-D 14-278 60 3.6e-151 508.49 In-house 1-261 (261) Show / Hide 
Range on Protein: 14-278
Range on HMM: 1-261/261
Sequence Identity: 60% (161 aa)

FKLTKKVSQGAFGEVFHGINLNTNMEVAVKLEPAKTKHPQLFFEVKLYQYLQRDANVADKGIPNVYYAATEREYNIMVMDLLGPSLEDLFNMCNRKFTVK
... .|.  |.||...|| |..|| |||.|||..||||||| .| |.|...|        |||.. .   | .||.||||||||||||||| |.||| .|
YRIGRKIGSGSFGDIYHGTNIQTNEEVAIKLECIKTKHPQLHIESKFYKMMQGGI-----GIPEIRWCGQEGDYNVMVMDLLGPSLEDLFNYCHRKFSLK

TTLMLADQLIQRVSYVHSKHFLHRDIKPDNFLIGTGKNAYKVFIIDFGLAKRYLKKD-GKHIEYKEGKSLTGTARYASLNTHLGIEQGRRDDLESLGYMF
| ||||||.|.|. |.|.. |.||||||||||.| ||    |.||||||||||      .|| |.| |.|||||||||.|||.|||| ||||||||||..
TVLMLADQMICRIEYIHCRNFIHRDIKPDNFLMGLGKRGNMVYIIDFGLAKRYRDARTHQHIPYRENKNLTGTARYASINTHQGIEQSRRDDLESLGYVL

MYFLRGSLPWQNLKATNKKDKYEKIMEKKLQTQVEELCKGFPSEFATYLAYTKNLRFDEKPDYEYL
||| ||||||| |||..|..|||.|.|||..|....||||.||||..|..|..||.||.|||| ||
MYFNRGSLPWQGLKAATKRQKYERICEKKMSTKIDTLCKGYPSEFQQYMNYCRNLKFDDKPDYCYL
Kinase 10222.AA CK1-G 14-278 55 7.70000000001e-142 477.51 In-house 1-266 (266) Show / Hide 
Range on Protein: 14-278
Range on HMM: 1-266/266
Sequence Identity: 55% (151 aa)

FKLTKKVSQGAFGEVFHGINLNTNMEVAVKLEPAKTKHPQLFFEVKLYQYLQRDANVADKGIPNVYYAATEREYNIMVMDLLGPSLEDLFNMCNRKFTVK
..  ||.  | |||.| | |. .|  ||.|.|| |.. |||  | . |. |   .     |||.|||   .  |||||||||||||||||..|.|||.||
YRVGKKIGCGNFGELFEGKNMYNNEHVAIKFEPMKSRAPQLHDEYRFYKILNGCP----EGIPQVYYFGQCGKYNIMVMDLLGPSLEDLFDWCDRKFSVK

TTLMLADQLIQRVSYVHSKHFLHRDIKPDNFLIG--TGKNAYKVFIIDFGLAKRYLKKD-GKHIEYKEGKSLTGTARYASLNTHLGIEQGRRDDLESLGY
|..|.| |.|.|. ||||.| . ||.||||||||    |.. ...|||||.|| |   . ..|| | | ||||||||| | ||||| || ||||.|.|| 
TVCMVAIQMIHRMEYVHSHHLIYRDVKPDNFLIGRPSNKDQHVIHIIDFGMAKQYIDPETKQHIPYREHKSLTGTARYMSINTHLGREQSRRDDMEALGH

MFMYFLRGSLPWQNLKATNKKDKYEKIMEKKLQTQVEELCKG--FPSEFATYLAYTKNLRFDEKPDYEYL
||||||||||||| ||| | | .|.|| ..| .| .| ||..  || .||||| |  .| |.|.|||.||
MFMYFLRGSLPWQGLKADNNKERYQKIGDTKRKTNIEDLCQNNAFPEQFATYLRYVRRLDFFECPDYDYL
Kinase 10222.AA CK1-A 14-278 59 3.5e-140 472.0 In-house 1-261 (261) Show / Hide 
Range on Protein: 14-278
Range on HMM: 1-261/261
Sequence Identity: 59% (157 aa)

FKLTKKVSQGAFGEVFHGINLNTNMEVAVKLEPAKTKHPQLFFEVKLYQYLQRDANVADKGIPNVYYAATEREYNIMVMDLLGPSLEDLFNMCNRKFTVK
..| .|.  |.||... |||..   |||.|.| .| .|||| .| |.|. ||.       |||.. .  .|..||.|||||||||||||||.|.|.||.|
YRLVRKIGSGSFGDIYLGINITNGEEVAIKMESNKARHPQLIYEAKVYRILQGCV-----GIPHMRWYGCEKDYNVMVMDLLGPSLEDLFNFCKRRFTMK

TTLMLADQLIQRVSYVHSKHFLHRDIKPDNFLIGTGKNAYKVFIIDFGLAKRYLKKDGK-HIEYKEGKSLTGTARYASLNTHLGIEQGRRDDLESLGYMF
| ||||||.| |. ||| | |.||||||||||.|.|.   |.|.|||||||.|  .  . ||.|.| | |||||||||.| |||||| ||||.||.||..
TVLMLADQMIMRIEYVHEKNFIHRDIKPDNFLMGIGRHCNKLFLIDFGLAKKYRDSRTRQHIPYREDKNLTGTARYASINAHLGIEQSRRDDMESMGYVM

MYFLRGSLPWQNLKATNKKDKYEKIMEKKLQTQVEELCKGFPSEFATYLAYTKNLRFDEKPDYEYL
||| ||.|||| .|| .|| ||||| |||. | .|.||||||.||. |..|..||||.|.||| ||
MYFNRGKLPWQGMKAMTKKQKYEKISEKKMSTPIEQLCKGFPAEFCMYMNYCRNLRFEEQPDYMYL
Kinase 10222.AA CK1 14-278 37 1.2e-133 450.29 In-house 1-339 (339) Show / Hide 
Range on Protein: 14-278
Range on HMM: 1-339/339
Sequence Identity: 37% (127 aa)

FKLTKKVSQGAFG-EVFHG-----INLNTN-----MEVAVKLEPAKTK--HPQLFFEVKLYQYLQRDANVAD---------------KGIPNVYYAATER
.|..||  .|.|| .....     .....|      |.|.|.||.|..  ||||  |...|..||. ..                  ...| .|. ..|.
WKVVKKIGEGGFGYQIYKVQKEDHKDMKNNKPYKGEEYAMKVEPKKSMGQHPQLMEEYQMYKKLQGGKKW-KASILKHKHFCKKHCGCPHPCMYWYHGEE

E--YNIMVMDLLGPSLEDLFN---MCNRKFTVKTTLMLADQLIQRVSYVHSKHFLHRDIKPDNFLIGT------GKNAY--------KVFIIDFGLAK-R
.  ||.|||.||||.||||..   ||||||..||.||.|.|..... |.|...|.|||||||||..|       ||.          .|..||||.|. .
DDYYNYMVMTLLGPNLEDLRKQNRMCNRKFSMKTWLMIAIQMLEALEYMHDCGFIHRDIKPDNFCMGRNESFKYGKH-HHEWNNEHRQVYMIDFGMARRK

YLKKDG------------KHIEYKE---GKSLTG-TARYASLNTHLGIEQGRRDDLESLGYMFMYFLRGS--LPWQNLKATNK-------KDKYEKIMEK
|..|||            .|....|    |...| ||||.|.|.|||.||||||||.|..||....|.|.  |||||.|. .|       | |||.|.||
YRDKDGHNRWNGPRDKTWQHRPPREHKKKKGFRGCTARYCSINCHLGKEQGRRDDLWSWFYMLIEWLKGTPGLPWQNMKDEMKPKDHQVEKMKYEFIDEK

KLQTQVEELCKG-----FPSEFATYLAYTKNLRFDEKPDYEYL
|..|... ||..     .|.|| ... | ..|.....||||..
KMSTPFF-LCCPKKDHDCPQEF-KIMKYIRSLKYYDRPDYEMI
Kinase 10222.AA TTBKL 14-282 28 5.2e-63 211.57 In-house 1-288 (288) Show / Hide 
Range on Protein: 14-282
Range on HMM: 1-288/288
Sequence Identity: 28% (86 aa)

FKLTKKVSQGAFGEVFHGINLNTNMEVAVKLEPAKT-KHPQ--LFFEVKLYQYLQ-RDANVADKGIPNVYYAATEREYNIMVMDLLGPSLEDLFNMCNRK
.. .|.. .|.||.|.|......  ..|.. |. ..  .    . .||..   || ... .    .|.....  .  || ||| |.||.| || .| ..|
WMIVKMIGEGGFGQVYHVWDMKDKKDCAAMKEEKNRLEGGDSRMKMEVHVLMKLQPNGSPH----FPKCHCSGKRKDYNFMVMTLCGPNLQDLRKMMPNK

--FTVKTTLMLADQLIQRVSYVHSKHFLHRDIKPDNFLIGTGKN----AYKVFIIDFGLAKRYLKKDG-----------KHIEYKE---GKSLTGTARYA
  |.. |.. .. |..  . ..|.. |.|||.|| |. .|  ..    .  |..||||.|..|..|||           .. . ..     .. || ||.
KRFSDGTWSRIGIQCLYALKQMHDCGFIHRDVKPCNCCWGYHDHSCERCRHVYLIDFGMARQYAWKDGEWNGPIHENKWMMRRPRNFRHKAPFRGTTRYC

SLNTHLGIEQGRRDDLESLGYMFMYFLRGSLPWQNLKATNKKDKYEKIMEKKLQTQVEELCKG------FPSEFATYLAYTKNLRFDEKPDYEYLRKLF
|.| |.. |||| ||| |. ||..... | |||.|.. .      ..|...|...  | |.|.      .||||.    . ..||. . ||||.....|
SPNMHDRKEQGRHDDLWSWMYMIIELHCG-LPWTNMEDK------MEIEHMKKNMKDEDLFKDMPRDHDCPSEFCKFMKHLRSLRYYDRPDYEMIYECF
Kinase 10222.AA Worm6 14-278 26 5.3e-59 202.32 In-house 1-279 (279) Show / Hide 
Range on Protein: 14-278
Range on HMM: 1-279/279
Sequence Identity: 26% (76 aa)

FKLTKKVSQGAFGEVFHGINLNTNM--EVAVKLEP--AKTKHPQLFFEVKLYQYLQRDA-----NVADKGIPNVYYAATERE-YNIMVMDLLGPSLEDLF
.|.|||. .|.|| |.   .  ..   ..|.|.|   .. |...| .|.   . . .       .. |.|        .... .| .|| |.|..|.|| 
WKVTKKIGEGGFGAVYKVEDKSDKKKKQFAMKCEKQMENMKRQMLKMECMVLKAVKHHKCRHFCKIEDRGK-------VDNRGFNYIVMTLVGKNLWDLR

NMC-NRKFTVKTTLMLADQLIQRVSYVHSKHFLHRDIKPDNFLIGT-----GKNAYKVFIIDFGLAK--RYLKKDGKHIEYK-EGKSLTGTARYASLNTH
  . .|||.. |.| .| | ....  .|. .|.|||.|| || ||       ..  .....|||...  .|. |... .  . .     || |||.|. |
KNRPDRKFSMGTGLKIAIQCLEAIEDLHNCGFIHRDVKPGNFCIGRYQMKEDNEHHTIYMLDFGMCRRKKYCNKGNELRTPRWTACGFRGTVRYAPLACH

LGIEQGRRDDLESLGYMFMYFLRGSLPWQNLKATNKKD-KYEKIMEKKLQTQVEELCKGFPS-EFATYLAYTKNLRFDEKPDYEYL
 |.||.|.||.||  ||   ...| |||...|... ..  ..... ..  .  ... ...|  ||   . |  .... ..|||...
KGQEQCRKDDCESWFYMMVEMIVGCLPWRHMKDHDHVEKHKKWCRRRTRAPMMRMFFGPCPKEEFNDIMDYIDQYSYWDRPDYKFI
Kinase 10222.AA TTBK 14-278 35 2.8e-55 189.95 In-house 1-257 (257) Show / Hide 
Range on Protein: 14-278
Range on HMM: 1-257/257
Sequence Identity: 35% (95 aa)

FKLTKKVSQGAFGEVFHGINLNTN-MEVAVKLEPAKTKHPQLFFEVKLYQYLQRDANVADKGIPNVYYAATEREYNIMVMDLLGPSLEDLFNMCNR-KFT
 | .||. .|.|||.. . .. ..  .||.|.| |...   |  ||   . ||    |        .    . ..| |||.|.| .| ||     | .|.
WKVVKKIGGGGFGEIYEAKDMINHHEQVAIKVESAQQPKQVLKMEVAVLKKLQGCDHVC-----RFIGCGRNDKFNYMVMQLQGKNLADLRRKQPRGCFS

VKTTLMLADQLIQRVSYVHSKHFLHRDIKPDNFLIG-TGKNAYKVFIIDFGLAKRYLKKDGKHIEYKEGKSLTGTARYASLNTHLGIEQGRRDDLESLGY
. ||| |  |..| .  .||  |||||||| || .| . ..  |....||||| .|.   |      |     ||.|||| | |.  | ||.||| || |
LSTTLRLGVQILQSIESIHSVGFLHRDIKPSNFAMGRNPSTCRKCYMLDFGLARQYTNACGEVRPPREVAGFRGTVRYASINAHRNREMGRHDDLWSLFY

MFMYFLRGSLPWQNLKATNKKDKYEKIMEKKLQTQVEELCKGFPSEFATYLAYTKNLRFDEKPDYEYL
|   |. | |||  .     ||| ... | | .     | |  |.|| ....  | | . ..|||  .
MLVEFVQGQLPWRKI-----KDK-DQVGEMKEKYDHRMLLKHCPHEFHQFMDHIKSLNYEDRPDYQLI
Kinase 10222.AA Pkinase 14-242 22 1.4e-32 116.31 Pfam 1-235 (293) Show / Hide 
Range on Protein: 14-242
Range on HMM: 1-235/293
Sequence Identity: 22% (55 aa)

FKLTKKVSQGAFGEVFHGINLNTNMEVAVKLEPAKTKHP----QLFF--EVKLYQYLQRDANVADKGIPNVYYAATEREYNIMVMDLLGPSLEDLFNMC-
... .|. .|.||.|..... .|. .||||  . .....    ...   |... . | .  |     |   |.. ... .  |||....  |. ..  . 
YHIGRKIGSGSFGCVYKCHHKGTGKIVAVKIIKKRHEKSWKDQTHRRLSEIQIMKRL-NHPN-----IVRLYDWFEDKDHIYMVMEYCEGGLY-VMDLFD

------NRKF--TVKTTLMLADQLIQRVSYVHSKHFLHRDIKPDNFLIG-TGKNAYKVFIIDFGLAKRYLKKDGKHIEYKEGKSLTGTARYASLNTHL-G
      ...|  . ..  . . |... . | ||. ..|||.||.|.||  .| .. .| |.|||||| .      .  .   ....|| .|..   .. |
YISTWRHGCFYFSEWECKFYMYQILRGLEYCHSMGIIHRDLKPENILIDNNGHIDACVKICDFGLAKQFD-----Y-NNS-MTTFCGTPWYMAPEVIRGG

IEQGRRDDLESLGYMFMYFLRGSLPWQNL----KATNKKDKYEKIMEKKL
 . |.. |  |.| .. ..| | .|...     .  ... ....||...|
QYYGPKVDMWSCGCILYEMLCGRPPFPGHCWHDN-HDQMQMICRIMGPPL
Kinase 10222.AA VRK 90-226 38 1e-27 86.15 In-house 106-244 (284) Show / Hide 
Range on Protein: 90-226
Range on HMM: 106-244/284
Sequence Identity: 38% (54 aa)

MVMDLLGPSLEDLFN-MCNRKFTVKTTLMLADQLIQRVSYVHSKHFLHRDIKPDNFLIGTGKNAYKVFIIDFGLAKRYLKKDGKHIEYKEGKSLT--GTA
|||. .| .|. .    .. .|. || | || ...    | |..   | |||  | | |  ||. .|. .|.||| || . .||| .|||..     || 
MVMPRFGRDLQKIYEDQNGHRFSMKTVLQLACRMLDVLEYLHENEYVHGDIKAANILLGFEKNPDQVYLVDYGLAYRY-CPNGKHRQYKEDPRRCHNGTC

RYASLNTHLGIEQGRRDDLESLGYMFMYFLRGSLPWQNLK
 . |.  |.|    || |||.|||  |. | |.||| ...
EFTSMDAHKGCAPSRRSDLEILGYCMMMWLYGYLPWMDCL
Kinase 10222.AA S_TKc 14-300 18 4.1e-16 59.43 SMART 1-231 (231) Show / Hide 
Range on Protein: 14-300
Range on HMM: 1-231/231
Sequence Identity: 18% (57 aa)

FKLTKKVSQGAFGEVFHGINLNTNMEVAVKLEPAKTKHPQLFFEVKLYQYLQRDANVADKGIPNVYYAATEREYNIMVMDLLGPSLEDLFNMCNRK----
... .|. .||||.|. ... .|. .||.|  .      ..  |... .          . | . |..  . ..  |||.... .| ||| .  ..    
YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK-----EHIRREIQILKK-------HHPNIVKLYDVFQD-DHLYMVMEYCDGDLGDLFDYIKKRGRHG

----FTVKTTLMLADQLIQRVSYVHSKHFLHRDIKPDNFLIGTGKNAYKVFIIDFGLAKRYLKKDGKHIEYKEGKSLTGTARYASLNTHLGIEQGR-RDD
    |.  ..  .. |... . | ||....|||.||.| |. .      . |.|||||...             ... ||  | .         |. . |
LRFPFPE-HARFYMYQICCALEYCHSHGIIHRDLKPENILLDE-----HIKICDFGLARQL-------------TTFCGTPWYMAPEVL---GYGKCKCD

LESLGYMFMYFLRGSLPWQNLKATNKKDKYEKIMEKKLQTQVEELCKGFPSEFATYLAYTKNLRFDEKPDYEYLRKLFK-DLFKRQGYEQDYQ-------
  |.| ..  .| |  |..     . .  ..||.                                 ..  . .||... |  || .  .  |       
WWSCGCILYEMLCGYPPFP-----QMQMMFKKIG--------------------------------SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKC

YDWK
  | 
HPWF
Kinase 10222.AA TyrKc 14-282 19 2.6e-07 -104.47 SMART 1-280 (280) Show / Hide 
Range on Protein: 14-282
Range on HMM: 1-280/280
Sequence Identity: 19% (59 aa)

FKLTKKVSQGAFGEVFHGINLNTNMEVAVKLEPAKTKHPQLFFEVKLYQYL--QRDANVADKGIPNVYYAATER-------EYNIMVMDLLGP-SLEDLF
 .| ||   ||||||..|.     ..||||   . . .  .  | ..   |  .       . | . | ..|.        |   .|| .    .| |  
ITLGKKLGEGAFGEVYKGTWK---IQVAVKMLKEDA-REDFMREARIMCKLGGH------HPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPHGDLKDYL

NMCNRKFTVKTTLMLADQLIQRVSYVHSKHFLHRDIKPDNFLIGTGKNAYKVFIIDFGLAKRYLKKDGK---HIEYKE--GKSLT--GTARYASLNTHLG
  . .|...|. |  . |  .  .| |||.. |||.   | |.| ..    | | ||||..    .| .   .  |.   .|.       |  .      
RKHRPKLCMKDLLSFCWQIACGMEYLHSKNCIHRDLAARNCLVGENH---TVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGKTMLPIRWMA------

IEQGRRDDLESLGYM--------FMY-------FLRGSLPWQNLKA--TNKKDKYEKIMEKKLQTQVEELCKG-----FPSEFATYLAYTKNLRFDEKPD
        .|.. |         ...       | .|  |. .      . .. .|.... .   | .. .        |.|  .      .   .. | 
--------PECINYGKFTTKSDVWSFGVCMWEIFTYGQQPYPGMIQQMMSNQEVIEYVKQGYRMPQPPNDY-PMSFVCCPDEMYQIMKQCWHEDPEDRPT

YEYLRKLF
 . ....|
FSEIHECF
Kinase 10222.AA Pkinase_Tyr 14-43 44 1.6e-05 19.37 Pfam 1-34 (270) Show / Hide 
Range on Protein: 14-43
Range on HMM: 1-34/270
Sequence Identity: 44% (15 aa)

FKLTKKVSQGAFGEVFHGINL----NTNMEVAVK
 .. ||  .||||||..|.      ||...||||
ITFGKKLGEGAFGEVYKGTWKGDPDNTKIPVAVK
Kinase 10222.AA VRK 14-62 27 0.073832 2.24 In-house 1-53 (284) Show / Hide 
Range on Protein: 14-62
Range on HMM: 1-53/284
Sequence Identity: 27% (15 aa)

FKLTKKVSQGAFGEVFHG---INLNT--NMEVAVKLEPAKTKHPQLFFEVKLYQ
..| |.  || ||. .      .  .  .    ||.||   .   || |.. ||
WRLGKPIGQGGFGCIYLASPNTCKPCEKDAQYVVKIEP-PHENGPLFTEMHFYQ