13287

Species: Tetrahymena
Alias: 4.m00686, 440, 3707.m00321, PreTt13287, TTHERM_00070970, 13287
External Links: Tetrahymena Genome Database (TGD)
Annotation:

Classification

Group: Other
Family: Aur

Sequence

Name Sequence Type Origin Length Description Download
13287.AA Protein None 496 None Fasta, JSON
13287.kin_dom Protein Kinase Domain None 253 None Fasta, JSON
13287.NA RNA None 1491 None Fasta, JSON

Protein domain

Protein domains of 13287.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Kinase 13287.AA Aur 97-349 48 1.5e-210 562.22 In-house 1-257 (257) Show / Hide
Range on Protein: 97-349
Range on HMM: 1-257/257
Sequence Identity: 48% (125 aa)

WANPGQLGAGSYGVVRLAYDKYTKERFAIKIMQKSQIFKFCTIDNLKREIKIQKRMVHPNICKLFHYFEDKQNVYLVLEYAQRGNLFSVLKKA--NKMDE
. . ..|| |..| |.||..|.|. .||.|.|.|.||.|.|....|.||||||... ||||.|...||.|.|..||.||||..|.|...|.|.  ...||
FEIGKPLGKGKFGNVYLARHKKTHFIFALKVMFKEQIKKYCMEHQLRREIKIQSHLNHPNILKMYGYFHDDQRIYLILEYAPGGELYKELQKQPNKRFDE

SVAFWYFYQTCLAIDHLHHNQIIHRDLKPENLLVDQ-GNNIKVCDFGWSAENSNNQIRTTFCGTVDYMAPEMVKRSTYDHRIDIWSLGVLLFELVHGYAP
  |..|.||.|.|.|..|...|||||.||||.|.||  .|||.||||||... ||..|.|||||.|||.||||.. ..||..|||.||||..||.||..|
QRAAKYMYQICNALDYCHSKNIIHRDIKPENILLDQCNGNIKICDFGWSVHCPNNNRRMTFCGTLDYMPPEMVEGQMHDHKVDIWCLGVLCYELCHGCPP

FQG-NNQNQKLDNISKNKPIQFRPNLEFDLVDLIKNILQPNPEYRLTMAQIFDHPWM
|.. .|.....|.|...  ||| ... ....|||..||| .|..|.|..||. |||.
FESNENHDETYDRIKNKVDIQFPSHISKEAKDLISKILQHDPKQRMTLDQIMNHPWI

Kinase 13287.AA AGC 103-349 24 7.69999999999e-106 274.07 In-house 7-395 (395) Show / Hide
Range on Protein: 103-349
Range on HMM: 7-395/395
Sequence Identity: 24% (98 aa)

LGAGSYGVVRLAYDK------YTKERFAIKIMQKSQ-IFKFC--TIDNLKRE------------IKIQKRMV----------HPNICK-LFHYFEDKQN-
.| ||.| |.|. .|       |.. .|.|...|.  | .    .... ..|             .| ...           ||.|.| |.. |.||.. 
IGKGSFGKVYLVRKKDGCHKKDTGKYYAMKVLKKKHKIVIKKKNMVEHTMTEHWKQDQGYVWEERNILEKCNHTHNHPIKSHHPFIVKILHYSFQDKDHT

-VYLVLEYAQ---------RG-NLFSVLK---KANKMDESVAFWYFYQ-------TCLAIDHLHH-NQIIHRD-LKPENLLVDQGNNIKVCDFGWSAENS
 .|.|.||..          |  ||. |.   |  ..||..|  |. .       ..||...||  . ||||| |||||.| |.  .|| .||| . |. 
YLYFVMEYMPRYVNDLYCGGGCELFLHLQGRRKEGRFDEERARFYAAEMQKICGCIVLALEYLHSHMGIIHRDYLKPENILLDEDGHIKLTDFGLCKEGM

NN---------------------------------------------------QIRTTFCG--TVDYMAPEMVKRSTYDHRIDIWS--LGVLLFELVHGY
|.                                                   .  .||||  | .|||||..    |..  |.||  ||.|..|.. ||
NDGEKGQQSQSNMKFHWHNKKYQKSNMDTNKCNPNNWQRNNMSQEDDTTRKKRDRTWTFCGPCTPEYMAPEIL----YGKACDWWSFGLGCLMYEMLTGY

APFQGNN----------QNQKLDNISK-----NKPIQFR----------PNLEFDLVDLIKNILQPNPEYRLT----------MAQIFDHPWM
 ||.|.|          .... ..| .     |....|           ...  ...||||  |...|| ||.            .| .||| 
PPFYGDNPQENRHPFRNPMEMFQKIMNGRYFINWKVKFPFPEDPQFPEDRWFSPEAKDLIKKLLCKDPEKRLGCGGNDFGDKGAEEIKNHPWF

Kinase 13287.AA MARK 97-349 39 1.6e-102 335.92 In-house 1-262 (262) Show / Hide
Range on Protein: 97-349
Range on HMM: 1-262/262
Sequence Identity: 39% (103 aa)

WANPGQLGAGSYGVVRLAYDKYTKERFAIKIMQKSQIFKFCTIDNLKREIKIQKRMVHPNICKLFHYFE--DKQN-VYLVLEYAQRGNLFSVLKKA--NK
     ..| |||..|.|| .| |....||||..| ........ |..|||.| |.. |||| ||||..|  ..|. .||..||| .|.|.. .|..   .
YKMLKTIGHGSYAKVKLACHKHTGRKVAIKIYEKFKLNDPQWMKNVMREIEIMKKLDHPNIIKLFHVIEQDTEQHQIYLIMEYASGGELYDYIKAHPNGR

MDESVAFWYFYQTCLAIDHLHHNQIIHRDLKPENLLVDQGN--NIKVCDFGWSAENSNNQIRTTFCGTVDYMAPEMVKRSTYD-HRIDIWSLGVLLFELV
. |. |  .| | . |.  .| . |.|||.||||.|.|. .  ||| .|||.|..  ..|  .|||||  |||||....  ||   .|||||||.|. .|
LHEEEARRIFRQIVSAVNYCHSKNIVHRDIKPENILIDENGNHNIKIIDFGFSICIPPGQKLNTFCGTPPYMAPEIFLKKPYDGPKVDIWSLGVVLYFMV

HGYAPFQGNN--QNQKLDNISKNKPIQFRPNLEFDLVDLIKNILQPNPEYRLTMAQIFDHPWM
.|| || | .  ...   .| . |.  . ...  .. .||. .|..|||.| |. .|  ||||
CGYFPFDGDTQDYKELYKKILRGKYD-IPCHVSKECRNLIQRLLTVNPEERPTIEEIMKHPWM

Kinase 13287.AA CAMKL 95-349 36 2.3e-102 327.52 In-house 1-297 (297) Show / Hide
Range on Protein: 95-349
Range on HMM: 1-297/297
Sequence Identity: 36% (109 aa)

YEWANPGQLGAGSYGVVRLAYD-KYTKERFAIKIMQKSQIF-KFCTIDN-----------LKREIKIQKRMV---HPNICKLFHYFEDKQN------VYL
|.     .|| ||.|.|.|| . ..|.|. ||||. |. |  . .. .|           ..|||.|.|..    ||||.||.. .|....      .||
YRIGK--TLGKGSFGKVKLATHIRTTGEKVAIKIIDKKKIWNDPWMKKNKCGQKHESDMRIRREIQIMKMLNIGKHPNIIKLYEVIETPEHDIETKKIYL

VLEYAQRGN--LFSVLKKA----NKMDESVAFWYFYQTCLAIDHLHHNQIIHRDLKPENLLVD-QGN-NIKVCDFGWSAE-----NSNNQIRTTFCGTVD
|.||.. |.  ||  ..|      .|.|. |  || | . |....| . |.|||.||||.|.| .|| |||..||| |..     . ..|  .||||.  
VMEYCSGGEMDLFDYIVKHGHRRGRMPEHEARRYFRQIVSAVNYCHSHGIVHRDIKPENILLDENGNNNIKIIDFGFSNMYRPCIFGPGQKLKTFCGSPP

YMAPEMVKR--STYD-HRIDIWSLGVLLFELVHGYAPFQ-------GNNQNQKLDNISKNKPIQFR--PNLEFDLVDLIKNILQPNPEYRLTMAQIFDHP
|||||....    ||   .||||.||.|. .| || ||        |.. . .| .. .    ...  . .  |. |||. .||.|||.| |. ||  ||
YMAPEIFQGNNKPYDGPKVDIWSCGVILYAMVCGYLPFDDDTYNKQGKDNI-YLYWKIMCG-YYPPIWYHVS-DCRDLIRKMLQVNPEKRPTIHQIMNHP

WM
||
WM

Kinase 13287.AA CAMK 102-349 24 1.9e-97 314.53 In-house 1-425 (425) Show / Hide
Range on Protein: 102-349
Range on HMM: 1-425/425
Sequence Identity: 24% (103 aa)

QLGAGSYGVVRLAYDKYTK------------ERFAIKIMQKSQIFKFC-------------------------TIDNLKREIKIQKRMV-------HPNI
.|| ||.|.|.|...| |.            ...||||. |... . .                         . .|..|||.| |..        ||||
TLGRGSFGKVKLCIHKNTTGKERVHHIYTNGQKVAIKIIDKKKLKDKQNQDYSNCYKIDKSKCKHRYCWRRPKDRKNVRREIEIMKKLQGIGNKLDHPNI

CKLFHYFED-------------------KQNVYLVL---EYAQRG----NLFSVLKKANK---------------MDESVAFWYFYQTCLAIDHLHHNQI
.||....||                   ....|.|.   ||.. |     ||. ...  .               ..|. |  || | | |....| . |
IKLYEVYEDPHYFKNTNDYETSKQVFTKDKHMYMVMEIMEYCSGGELFDDLFDYIVEHGCYGEEFDQFDIVERGRFTEREARRYFRQICSAVHYCHSHNI

IHRDLKPENLLVDQG-----------------NNIKVCDFGWS--AENSN----------------------NQIRTTFCGTVDYMA-PEMVKRST----
.||||||||.|.|.                  ||||..||| .   . ..                      .|  .|||||  ||| ||......    
VHRDLKPENILLDDNNDDSDPVEHDEIFDWNNNNIKIIDFGFANKFDPGENNFMCSDYKGGEMHNQWTTPTEGQKMKTFCGTPEYMAAPEVLNGKGHCNM

----------YDHRIDIWSLGVLLFELVHGYAPFQGNNQNQKLD------NIS----KNKPIQFR-PNLEFD-------------------------LVD
          |.  .|.||.||.|. .. || ||.| ..|. ..      |..    | .  ... |  .|.                           |
QNATDEEKPYYGPKCDMWSCGVILYIMLCGYPPFYGDCDNEICEDEWIGMNDYELFEKIMKGKYDFPPPYFSPISCNYGPEWWDDISDEFHHFVSQECKD

LIKNILQPNPEYRLTMAQIFDHPWM
||...||..|| |.| .|. .||||
LIRKMLQVDPEKRMTIEQCLNHPWM

Kinase 13287.AA S_TKc 97-349 34 4.4e-97 329.74 SMART 1-231 (231) Show / Hide
Range on Protein: 97-349
Range on HMM: 1-231/231
Sequence Identity: 34% (92 aa)

WANPGQLGAGSYGVVRLAYDKYTKERFAIKIMQKSQIFKFCTIDNLKREIKIQKRMVHPNICKLFHYFEDKQNVYLVLEYAQR--GNLFSVLKKANK---
.    ..| |..|.|.....| |....||||.           ....|||.| |.  ||||.||. .|.| ...|.|.||.    |.||...|| ..   
YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK----------EHIRREIQILKK-HHPNIVKLYDVFQD-DHLYMVMEYCDGDLGDLFDYIKKRGRHGL

---MDESVAFWYFYQTCLAIDHLHHNQIIHRDLKPENLLVDQGNNIKVCDFGWSAENSNNQIRTTFCGTVDYMAPEMVKRSTYDH-RIDIWSLGVLLFEL
   ..| .|  |.||.|.|....| ..||||||||||.|.|.  .||.|||| ...       |||||| .|||||..    |.. ..|.||.|..|.|.
RFPFPE-HARFYMYQICCALEYCHSHGIIHRDLKPENILLDE--HIKICDFGLARQL------TTFCGTPWYMAPEVL---GYGKCKCDWWSCGCILYEM

VHGYAPFQGNNQNQKLDNISKNKPIQFRPNLEFDLVDLIKNILQPNPEYRLTMAQIFD-------HPWM
. || ||.  .... ...|              .. |.|...|| .|| |.|  ...        |||.
LCGYPPFP--QMQMMFKKIG-----------SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF

Kinase 13287.AA Pkinase 97-349 32 2.4e-93 321.19 Pfam 1-293 (293) Show / Hide
Range on Protein: 97-349
Range on HMM: 1-293/293
Sequence Identity: 32% (96 aa)

WANPGQLGAGSYGVVRLAYDKYTKERFAIKIMQKSQIFKFCTIDNLK-REIKIQKRMVHPNICKLFHYFEDKQNVYLVLEYAQRG----NLFSVLK--KA
.   ...|.||.|.|.....| | ...|.||. |. . . . . ... .||.| ||. ||||..|...||||...|.|.||.. |     ||....  . 
YHIGRKIGSGSFGCVYKCHHKGTGKIVAVKIIKKRHEKSWKDQTHRRLSEIQIMKRLNHPNIVRLYDWFEDKDHIYMVMEYCEGGLYVMDLFDYISTWRH

NKM--DESVAFWYFYQTCLAIDHLHHNQIIHRDLKPENLLVDQGNNI----KVCDFGWSAE--NSNNQIRTTFCGTVDYMAPEMVK-RSTYDHRIDIWSL
...  .| ..  |.||.. .....| . ||||||||||.|.|. ..|    |.|||| ..   . ||.  |||||| .||||| .. .. |....|.||.
GCFYFSEWECKFYMYQILRGLEYCHSMGIIHRDLKPENILIDNNGHIDACVKICDFGLAKQFDY-NNS-MTTFCGTPWYMAPEVIRGGQYYGPKVDMWSC

GVLLFELVHGYAPFQGN------NQNQKLDNISKNKPIQFRP--------------------NLEFDLVDLIKNILQPNPEYRLTMAQIFDHPWM
|..|.|.. |. ||.|       .|.|....| . ..   .|                    |.. .. |.||..|...|. |.| .||. |||.
GCILYEMLCGRPPFPGHCWHDNHDQMQMICRIMGPPLHFDWPWWCSISYFFFRHWHFHWTFHNWSEECKDFIKWCLCKDPKKRPTAEQILQHPWF

Kinase 13287.AA Ciliate-E2-Unclassified 102-349 31 4.5e-81 275.66 In-house 6-352 (352) Show / Hide
Range on Protein: 102-349
Range on HMM: 6-352/352
Sequence Identity: 31% (111 aa)

QLGAGSYGVVRLAYDKYTKERFAIKIMQKSQIFKFCTI---DNLKREIKIQKRMV-------------------HPNICKLFHYFEDKQNVYLVLEYAQR
|.| |..|.|.....| .|. .|.|.| |.||.| . |   |....|.|. ...                    ||.| |.|..|.||||.|.|.||.. 
QIGQGGFGKVYKCQHKKQKQYYAMKYMKKIQIYKQKQIMNKDEIMNEMKEMNNKKKYHQRKYNKIMQQILLNHPHPFIVKMFYCFQDKQNIYIVMEYCEG

GNLFSVLKKANK-----------------MDESVAF-----WYFYQTCLAIDHLHHNQ-IIHRDLKPENLLVDQGN---NIKVCDFGWSAENSNN-----
|.|.  .|| .|                  .|  |       ||.| ......|||.. |||||.||||.|.|...   .||..||| | .. .|     
GDLWQYIKKRKKQKQKGNDLFHNMKQRKIFTEQQAKYKKAKFYFAQILQGLEYLHHKNNIIHRDIKPENILFDNNGKNYYIKIIDFGISKKYQQNNNCDT

-----------QIRTTFCGTVDYM----APEMVKRSTYDHR----IDIWSLGVLLFELVHGYAPFQGNNQNQ---------------KLDNISKNKPIQF
           |. .|||||  ||    |||. ..  |||.    .|||||||.|.|.. || ||..||..|                | .. |.|.|||
NQQQKMQIWKQQMMWTFCGTPNYMPQYTAPEVLQGQNYDHSKAYKCDIWSLGVILYEMLFGYYPFYDNNCEQHQQLITQWINNAYRKQLYQNIKQKNIQF

RP--------NLEFDLVDLIK----NILQPNPEYRLTMAQIFDHPWM
..        .. .   |.|.     .|. ||..|.|. ||. |||.
PKFPWQQIPKHWSPEAKDFINDLLQKMLKKNPNKRITFEQILNHPWF

Kinase 13287.AA Ciliate-E2 102-349 25 1.4e-78 267.35 In-house 6-365 (365) Show / Hide
Range on Protein: 102-349
Range on HMM: 6-365/365
Sequence Identity: 25% (96 aa)

QLGAGSYGVVRLAYDKYTKERFA-----------------------IKIMQKSQIFKFCTIDNLKREIK----------IQKRMVHPNICKLFHYFE--D
..| |..|.|... .. ....||                       .|||.|.||. .  .... |||.          |.... ||||.|.. .|.  |
KIGQGNFGSVYKCKVWKVQKQFAIKIIDQKQQRQQMQEKVKIKIYAMKIMKKNQIEQIKQEIHIMREINCFYKKINEKNILEQLNHPNIIKMYECFQEKD

KQNVYLVLEYAQRGNLFSVLK------------KANKMDESVAFWYFYQTCL---------------AIDHLHHNQ-IIHRDLKPENLLVDQGNNIKVCD
..|.|||.||.| |.||. .|            . ....|  .  ...| .                |. .|| .  |||||.||||.|.     ||..|
DNNIYLVMEYCQGGDLFDYIKNNKKKRNHEIEKD-KYFTEKEIKYIMKQILQGFKTKAEFYIACIILALEYLHSKNNIIHRDIKPENILF-----IKIID

FGWSAENSNNQIRTT--------------------------------FCGTVDYMAPEMVKRST---------YDHRIDIWSLGVLLFELVHGYAPFQGN
|| | .........|                                .|||  |||||....           ||. .|||||||.|.|.. |. ||   
FGLSKKYDDDNQNRTHKQQCKWYMFKNDTSRTPGYMDQIIQQNMFNTICGTPGYMAPEILNGKKYDNQQKQKGYDYKCDIWSLGVILYEMLFGKPPF---

NQNQKLDNISKNKPIQFRPNL-------------EF-----DLVDLIKN----ILQPNPEYRLT-MAQIFDHPWM
       .. |...|.|...              ..     .  ||||.    .|| .|| |.| . ||..|||.
------QQQIKQCKIDFPCPEWQKDTQCIQCKWKSWKKWSQECKDLIKKFGKRMLQKDPEKRITGWEQILNHPWF

Kinase 13287.AA RSK 97-349 34 2.9e-77 262.98 In-house 1-278 (278) Show / Hide
Range on Protein: 97-349
Range on HMM: 1-278/278
Sequence Identity: 34% (96 aa)

WANPGQLGAGSYGVVRLAYDKYTKERFAIKIMQKSQIFKFCT-IDNLKREIKIQKRMV-HPNICKLFHYFEDKQNVYLVLEYAQRGNLFSVLKKANK---
    ||.| |.. ..|   .. |.  .| |. .|. | .  . .   ..|..| .|   ||.|..|.. |.... .||..||   | ||  |.|      
LKVLGQGGYGKVFLCRKCTHHDTGQIYAMKVLKKAKIVQRQKDTRHTMTERNILERCQQHPFIVTLHYAFQTEGKLYLIMEYCRGGELFTHLQKEKHFGC

MDESVAFWYFYQTCLAIDHLHHNQIIHRDLKPENLLVDQ---GNNIKVCDFGWSAE--NSNNQIRTTFCGTVDYMAPEMVK----RSTYDHRIDIWSLGV
..|. |  |...  ||..|||  .|||||||||| | |.      ||..||| . .  ...||   |||.|..||||||.|    ....|.  |.|||||
FSEDEACFYMAEIVLAVEHLHQQGIIHRDLKPENILYDDESNEGHIKLTDFGFCKQFRCDHNQWTMTFCYTIEYMAPEMLKRANQQGGHDKACDWWSLGV

LLFELVHGYAPFQG---NNQNQKLDNISKNK-PIQFR--PNLEFDLVDLIKNILQPNPEYRLT-----MAQIFDHPWM
|..|.  |. ||||   ||... ...| |.|    .   ..|  .  |||.  |. .|. ||.     ...| .|||.
LMYEMLTGCPPFQGPNDNNRKEIMKRIQKGKFSLTMPNWQYLSQEAKDLIRKMLHRDPHKRLGCGPQDAEEIKQHPWF

Kinase 13287.AA ULK 97-349 28 1.7e-74 253.79 In-house 1-329 (329) Show / Hide
Range on Protein: 97-349
Range on HMM: 1-329/329
Sequence Identity: 28% (93 aa)

WANPGQLGAGSYGVVRLAYDKYTK----ERFAIKIMQ---KSQIFKFCT----IDNLKREIKIQKRMV--------HPNICKLFHYFEDK--QNVYLVLE
.    .|| ||.|.|  ...| ||    | .|.|...   ..|. .  .    .. ||.||||.|..         ||||.||...||..   |.|...|
YCLNHCLGKGSFGKVYKGRNKKTKDYVNEKVACKMIDKQKMNQKNNEQEGQYMWQLLKNEIKIMKKLKSPNRHKNHHPNIVKLYDWFETSNHNNIYIIME

YAQRGNLFSVLKKANKMDESV----------AFWYFYQTCLAIDHLHHNQIIHRDLKPENLLVDQGNN------------IKVCDFGWSAENSNN----Q
| . |.|.. .|| .|. |..          |  .|.| . .  .|| ..|||||.||.| |.. |.             .|..||| .   .|.    |
YCNGGDLEQYIKKNKKLPEDTEEKKRLSEQEAIQFFKQILNGFKELHKHNIIHRDIKPQNILIHNGQPKTDSKKVHPNGVLKIADFGFAKHVDNDNMEQQ

IRTTFC------GTVDYMAPEMVK----RSTYD-HRIDIWSLGVLLFELVHGYAPFQGNNQNQKL-----DNISK---------NKPIQFR-----PNLE
. .|.       ||  ||||. ..    .  |. .  ||||||....|.. |. ||...  |.       ..| .         ..|.||.     |.. 
MMMTCVNEKRLCGTPLYMAPQILQGQGEQKPYYDYKCDIWSLGCIFYEMLYGKPPFYAW-FNDQYLQIIQKLINNPPPWPQQIKKQPLQFPKDGNDPQIS

FDLVDLIKNILQPNPEYRLTMAQIFDHPWM
 .. |||.  || ... | .  ..|.|||.
PECKDLIRRMLQYDEKDRISWEELFNHPWF

Kinase 13287.AA ULK 97-349 29 6.5e-74 251.87 In-house 1-324 (324) Show / Hide
Range on Protein: 97-349
Range on HMM: 1-324/324
Sequence Identity: 29% (96 aa)

WANPGQLGAGSYG-VVRLAYDKYT---KERFAIKIMQKSQIFKFCT-------IDNLKREIKIQKRMV---HPN--ICKLFHYFEDK--QNVYLVLEYAQ
.    .|| ||.| .|  ...| |   .. .|.|...|... |.         ...||.||.|.| .    |||  |.||...||..   |.|...|| .
YCLNHCLGKGSFGVKVYKGRNKKTNTQNQYVACKMIDKKKMNKKKNEQEGQYMWQLLKNEIQIMKKLKELKHPNHHIVKLYDWFETSNHNNIYIIMEYCN

RGNLFSVLKKANK---------MDESVAFWYFYQTCLAIDHLHHNQIIHRDLKPENLLVDQGNN------------IKVCDFGWSAE-NSNN---QIRTT
 |.|.. .|| .|           |. |  .|.| | .  .|| ..|||||.||.|.|.  |.             .|..||| .   ..||   |...|
GGDLEQYIKKNKKLPETEEKKRLSEQEAIQFFKQICNGFKELHKHNIIHRDIKPQNILIHNGQPKTDSKKVHPNGVLKIADFGFAKHVDNNNMEQQMCQT

FC------GTVDYMAPEMVK----RSTYD-HRIDIWSLGVLLFELVHGYAPFQGNNQNQKL----DNISK---------NKPIQFR-----PNLEFDLVD
..      ||  ||||. ..    .  |. .  ||||||....|.. |. ||...  |.      . | .         |.||||.     |..  .. |
CVNEKRIKGTPLYMAPQILQGQGEQKPYYDYKCDIWSLGCIFYEMLYGKYPFFSW-FNDQYLYIQKLINNGKEQQIYIKNQPIQFPKPPKDPKISPECKD

LIKNILQPNPEYRLTMAQIFDHPWM
||.  || ... | .  .||.|||.
LIRRMLQYDEKDRISWEEIFNHPWF

Kinase 13287.AA TyrKc 102-349 22 5.2e-20 73.71 SMART 6-280 (280) Show / Hide
Range on Protein: 102-349
Range on HMM: 6-280/280
Sequence Identity: 22% (63 aa)

QLGAGSYGVVRLAYDKYTKERFAIKIMQKSQIFKFCTIDNLKREIKIQKRM--VHPNICKLFHYFEDK-------QNVYLVLEYAQRGNLFSVLKKANK-
.|| | .|.|...  |   .  |.| ....       .  . ||..| ..    |||| .|. .  ..       . ...|.||.  |.| . |.|  . 
KLGEGAFGEVYKGTWK---IQVAVKMLKEDA------REDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPHGDLKDYLRKHRPK

MDESVAFWYFYQTCLAIDHLHHNQIIHRDLKPENLLVDQGNNIKVCDFGWSAENSNN--------QIRTTF--CGT----VDYMAPEMVKRSTYDHRIDI
   .    . .| .   ..||....|||||   | ||. .. .|..||| | .  .          .|..   .|     .  ||||  . ... .  |.
LCMKDLLSFCWQIACGMEYLHSKNCIHRDLAARNCLVGENHTVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGKTMLPIRWMAPECINYGKFTTKSDV

WSLGVLLFELV-HGYAPFQG-----NNQNQKLDNISKNKPIQFRPN--------LEFDLVDLIKNILQPNPEYRLTMAQIFDHPWM
|| ||...|.   |  |  |      .  . . .. . .     ||           .. ...|   . .|| | |...|  |  .
WSFGVCMWEIFTYGQQPYPGMIQQMMSNQEVIEYVKQGYRMPQPPNDYPMSFVCCPDEMYQIMKQCWHEDPEDRPTFSEI--HECF

Kinase 13287.AA Pkinase_Tyr 102-240 28 1.1e-14 50.4 Pfam 6-156 (270) Show / Hide
Range on Protein: 102-240
Range on HMM: 6-156/270
Sequence Identity: 28% (45 aa)

QLGAGSYGVVRLAYDK----YTKERFAIKIMQKSQIFKFCTIDN-----LKREIKIQKRM-VHPNICKLFHYFE-DKQN--VYLVLEYAQRGNLFSVLKK
.||.|..|.|.... |     ||   |.|.. |      .. ..     . ||.|| | .  |||| .|      ...   .|.|.||.. |.| . |.|
KLGEGAFGEVYKGTWKGDPDNTKIPVAVKML-KE----GAMHEQNCREDFMREAKIMKQLGHHPNIVRLYGVCTDQGEPNQIYIVMEYMPHGDLLDYLRK

----ANKMDESVAFWYFYQTCLAIDHLHHNQIIHRDLKPENLLVDQGNNIKVCDFG
     .. . .    . .| . . ..|. ...|||||   | ||. .| .|.||||
HREDKQPLTMKDLLQMCWQIAKGMEYLESKNCIHRDLAARNCLVTENNVVKICDFG

Kinase 13287.AA Pkinase_Tyr 261-296 36 0.001966 12.25 Pfam 181-218 (270) Show / Hide
Range on Protein: 261-296
Range on HMM: 181-218/270
Sequence Identity: 36% (14 aa)

MAPEMVKRSTYDHRIDIWSLGVLLFELVH-GYAP-FQG
||||  . . . .  |.|| |||..|..  |  | ..|
MAPECINYGKFTTKSDVWSFGVLMWEIFTYGEQPTYPG