Gene 26122 (Tetrahymena)
26122
Sequence
Protein domains of 26122.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.
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| Domain | Protein name | Domain Name | Range | Identity (%) | Significance | Score | Profile Source | Profile Range (length) | Alignment |
|---|---|---|---|---|---|---|---|---|---|
| Kinase | 26122.AA | Aur | 85-336 | 62 | 5.1e-238 | 636.16 | In-house | 1-257 (257) | Show / Hide |
Range on Protein: 85-336 Range on HMM: 1-257/257 Sequence Identity: 62% (160 aa) FELGKPLGRGKFGQVHLAREKRSNFIVALKCISKEQLRRSKIEHQIRREIEIQSHLNHKNVLRMFGFFWDEQKIYLILEYAPQGELYQDLQKQINKRYPE ||.|||||.||||.|.|||.| ..||.|||...|||.. ...|||.||||.||||||| |.|.|.|.|.|.|.|||||||||.||||. ||||.|||..| FEIGKPLGKGKFGNVYLARHKKTHFIFALKVMFKEQIKKYCMEHQLRREIKIQSHLNHPNILKMYGYFHDDQRIYLILEYAPGGELYKELQKQPNKRFDE QKAANYIKQMAEALIYLHSKDIIHRDIKPENLLNS--FGTIKIADFGWSIHSP-SNKRQTICGTLDYLSPEMVEGNTHNYTVDIWSLGVLCYEFCTGQPP |.||.|..|...||.|.|||.||||||||||.|.. |.|||.|||||.| | .|.|.| ||||||..||||||..|...||||.|||||||.|.|.|| QRAAKYMYQICNALDYCHSKNIIHRDIKPENILLDQCNGNIKICDFGWSVHCPNNNRRMTFCGTLDYMPPEMVEGQMHDHKVDIWCLGVLCYELCHGCPP FET-KSYDQTYDRIK-KVQFSFPDYLSIEVRDLLSKILVYEKSQRLDLNNILNHPWI || ...|.|||||| ||...||...|.|..|| ||||... .||. |. |.||||| FESNENHDETYDRIKNKVDIQFPSHISKEAKDLISKILQHDPKQRMTLDQIMNHPWI |
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| Kinase | 26122.AA | AGC | 85-336 | 23 | 2.2e-109 | 283.43 | In-house | 1-395 (395) | Show / Hide |
Range on Protein: 85-336 Range on HMM: 1-395/395 Sequence Identity: 23% (95 aa) FELGKPLGRGKFGQVHLAREK------RSNFIVALKCISKEQ---LRRSKIEHQIRRE------------IEIQSHLN----------HKNVLR-MFGFF ||. |..|.| ||.|.|.|.| .. . |.|...|. ... . .... .| .| ...| | .. . .. | FEFLKVIGKGSFGKVYLVRKKDGCHKKDTGKYYAMKVLKKKHKIVIKKKNMVEHTMTEHWKQDQGYVWEERNILEKCNHTHNHPIKSHHPFIVKILHYSF WDEQK--IYLILEYAP---------QG-ELYQDLQKQ-INKRYPEQKAANYIKQ-------MAEALIYLHS-KDIIHRD-IKPEN-LLNSFGTIKIADFG |... .|...||.| | ||.. ||.. ..| .|. | |. . .. || |||| ..||||| .|||| ||.. | ||..||| QDKDHTYLYFVMEYMPRYVNDLYCGGGCELFLHLQGRRKEGRFDEERARFYAAEMQKICGCIVLALEYLHSHMGIIHRDYLKPENILLDEDGHIKLTDFG WSIHSPS----------------------------------------------------NKRQTICG--TLDYLSPEMVEGNTHNYTVDIWS--LGVLCY . .. .. .|.|| | .|..||.. .....|.|| ||.| | LCKEGMNDGEKGQQSQSNMKFHWHNKKYQKSNMDTNKCNPNNWQRNNMSQEDDTTRKKRDRTWTFCGPCTPEYMAPEIL----YGKACDWWSFGLGCLMY EFCTGQPPFETKS----------YDQTYDRIK--------KVQFSFP--------DYLSIEVRDLLSKILVYEKSQRLD----------LNNILNHPWI |. ||.||| .. ......|. ||.| || ...| | .||..| |. . ..|| . | |||| EMLTGYPPFYGDNPQENRHPFRNPMEMFQKIMNGRYFINWKVKFPFPEDPQFPEDRWFSPEAKDLIKKLLCKDPEKRLGCGGNDFGDKGAEEIKNHPWF |
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| Kinase | 26122.AA | CAMK | 90-336 | 21 | 9.8e-98 | 315.51 | In-house | 1-425 (425) | Show / Hide |
Range on Protein: 90-336
Range on HMM: 1-425/425
Sequence Identity: 21% (93 aa)
PLGRGKFGQVHLAREKRSN------------FIVALKCISKEQLR-------------------------RSKIEHQIRREIEIQSH-------LNHKNV
|||| ||.|.|...|... || | |.|..|. | | ....|||||| .. |.|.|.
TLGRGSFGKVKLCIHKNTTGKERVHHIYTNGQKVAIKIIDKKKLKDKQNQDYSNCYKIDKSKCKHRYCWRRPKDRKNVRREIEIMKKLQGIGNKLDHPNI
LRMFGFFWD-------------------EQKIYLIL---EYAPQGELYQDLQKQINKR-----------------YPEQKAANYIKQMAEALIYLHSKDI
.... .. | ....|... ||.. |||..|| | .. ..|. |. |..|...|. |.||..|
IKLYEVYEDPHYFKNTNDYETSKQVFTKDKHMYMVMEIMEYCSGGELFDDLFDYIVEHGCYGEEFDQFDIVERGRFTEREARRYFRQICSAVHYCHSHNI
IHRDIKPENLLNS--F----------------GTIKIADFGWSIHSPSNK-------------------------RQTICGTLDYLS-PEMVEGNT----
.|||.||||.| . . ..|||.||| ... .... .| |||. | . ||...|..
VHRDLKPENILLDDNNDDSDPVEHDEIFDWNNNNIKIIDFGFANKFDPGENNFMCSDYKGGEMHNQWTTPTEGQKMKTFCGTPEYMAAPEVLNGKGHCNM
----------HNYTVDIWSLGVLCYEFCTGQPPFETK-------------SYDQTYDRIKKVQFS-FPDYLSI-----------------------EVRD
... .|.||.||..| .| |||. . .. ... .|.| ... |.|.|. |..|
QNATDEEKPYYGPKCDMWSCGVILYIMLCGYPPFYGDCDNEICEDEWIGMNDYELFEKIMKGKYDFPPPYFSPISCNYGPEWWDDISDEFHHFVSQECKD
LLSKILVYEKSQRLDLNNILNHPWI
|..|.|... ..|. . .|||||.
LIRKMLQVDPEKRMTIEQCLNHPWM
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| Kinase | 26122.AA | S_TKc | 85-336 | 31 | 2.5e-95 | 323.9 | SMART | 1-231 (231) | Show / Hide |
Range on Protein: 85-336 Range on HMM: 1-231/231 Sequence Identity: 31% (83 aa) FELGKPLGRGKFGQVHLAREKRSNFIVALKCISKEQLRRSKIEHQIRREIEIQSHLNHKNVLRMFGFFWDEQKIYLILEYAPQ--GELYQDLQKQINKR- .|.....|.| ||.|...|.|... |||.|.|. .|||||.| .. .|.|. .....| | ...|...||... |.|.. ..|. .. YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK----------EHIRREIQILKK-HHPNIVKLYDVFQD-DHLYMVMEYCDGDLGDLFDYIKKRGRHGL ---YPEQKAANYIKQMAEALIYLHSKDIIHRDIKPENLLNSFGTIKIADFGWSIHSPSNKRQTICGTLDYLSPEMVEGNTHNY-TVDIWSLGVLCYEFCT .|| |. |..|...|| |.||. |||||.||||.| . .|||.||| . . |.|||..|..||.. ... .|.||.|.. ||... RFPFPE-HARFYMYQICCALEYCHSHGIIHRDLKPENILLDE-HIKICDFGLARQL-----TTFCGTPWYMAPEVL---GYGKCKCDWWSCGCILYEMLC GQPPFETKSYDQTYDRIKKVQFSFPDYLSIEVRDLLSKILVYEKSQRLDLNNILN-------HPWI |.|||. .......|. | |..|...|.|... ..|. .|. |||. GYPPFP--QMQMMFKKIG----------SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF |
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| Kinase | 26122.AA | Ciliate-E2 | 85-336 | 27 | 2.5e-85 | 289.81 | In-house | 1-365 (365) | Show / Hide |
Range on Protein: 85-336
Range on HMM: 1-365/365
Sequence Identity: 27% (103 aa)
FELGKPLGRGKFGQVHLARE-----------------------KRSNFIVALKCISKEQLRRSKIEHQIRREIE----------IQSHLNHKNVLRMFGF
... | .|.| ||.| ... | ..|.|.|...| |.. | | .| |||. |...|||.|...|. .
YKFIKKIGQGNFGSVYKCKVWKVQKQFAIKIIDQKQQRQQMQEKVKIKIYAMKIMKKNQIEQIKQEIHIMREINCFYKKINEKNILEQLNHPNIIKMYEC
FW--DEQKIYLILEYAPQGELYQDLQKQINKR---------YPEQKAANYIKQMAE---------------ALIYLHSKD-IIHRDIKPENLLNSFGTIK
| |...|||..||. .|.|.. .... || . |.......|| .. || ||||| ||||||||||.| ||
FQEKDDNNIYLVMEYCQGGDLFDYIKNNKKKRNHEIEKDKYFTEKEIKYIMKQILQGFKTKAEFYIACIILALEYLHSKNNIIHRDIKPENILF----IK
IADFGWSIHSPSNKR---------------------------------QTICGTLDYLSPEMVEGNT---------HNYTVDIWSLGVLCYEFCTGQPPF
|.||| | . .|||||. |..||...| ..| .|||||||. ||...|.|||
IIDFGLSKKYDDDNQNRTHKQQCKWYMFKNDTSRTPGYMDQIIQQNMFNTICGTPGYMAPEILNGKKYDNQQKQKGYDYKCDIWSLGVILYEMLFGKPPF
ETKSYDQTYDRIKKVQFSFP------------------DYLSIEVRDLLSK----ILVYEKSQRLD-LNNILNHPWI
.. ||. ...|| ...| |. ||..| .|... ..|.. . ||||||.
--------QQQIKQCKIDFPCPEWQKDTQCIQCKWKSWKKWSQECKDLIKKFGKRMLQKDPEKRITGWEQILNHPWF
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| Kinase | 26122.AA | CAMKL | 85-336 | 32 | 1.1e-84 | 270.15 | In-house | 1-297 (297) | Show / Hide |
Range on Protein: 85-336 Range on HMM: 1-297/297 Sequence Identity: 32% (98 aa) FELGKPLGRGKFGQVHLARE-KRSNFIVALKCISKEQLR-RSKIEHQ-----------IRREIEIQSHLN---HKNVLRMFGFFWDEQK------IYLIL ...|| ||.| ||.| ||. . . || | | |. .. . ... |||||.|...|| |.|. ... . .... |||.. YRIGKTLGKGSFGKVKLATHIRTTGEKVAIKIIDKKKIWNDPWMKKNKCGQKHESDMRIRREIQIMKMLNIGKHPNIIKLYEVIETPEHDIETKKIYLVM EYAPQGE--LYQDLQKQINKR--YPEQKAANYIKQMAEALIYLHSKDIIHRDIKPENLLNS-FG--TIKIADFGWSIH-SP-----SNKRQTICGTLDYL ||.. || |.. ..|. ..| || | | .|. .|. |.||..|.||||||||.| . | .|||.||| |.. | .| | ||.. | EYCSGGEMDLFDYIVKHGHRRGRMPEHEARRYFRQIVSAVNYCHSHGIVHRDIKPENILLDENGNNNIKIIDFGFSNMYRPCIFGPGQKLKTFCGSPPYM SPEMVEG--NTHN-YTVDIWSLGVLCYEFCTGQPPFETKSYD-------QTYDRIKKVQFSFP--DYLSIEVRDLLSKILVYEKSQRLDLNNILNHPWI .||...| .. . |||||.||. | .|. ||. .| | .|.. . .| ..| ..|||..|.|. ..| . .|.|||| APEIFQGNNKPYDGPKVDIWSCGVILYAMVCGYLPFDDDTYNKQGKDNIYLYWKIMCG-YYPPIWYHVS-DCRDLIRKMLQVNPEKRPTIHQIMNHPWM |
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| Kinase | 26122.AA | MARK | 85-336 | 37 | 2.3e-81 | 265.75 | In-house | 1-262 (262) | Show / Hide |
Range on Protein: 85-336 Range on HMM: 1-262/262 Sequence Identity: 37% (99 aa) FELGKPLGRGKFGQVHLAREKRSNFIVALKCISKEQLRRSKIEHQIRREIEIQSHLNHKNVLRMFGFFW--DEQK-IYLILEYAPQGELYQDLQKQINKR ....| .| | ...| ||. |... ||.| . |..| . . ..||||| ..|.|.|. ..| . .||. ||||.|||. ||||. .... | | YKMLKTIGHGSYAKVKLACHKHTGRKVAIKIYEKFKLNDPQWMKNVMREIEIMKKLDHPNIIKLFHVIEQDTEQHQIYLIMEYASGGELYDYIKAHPNGR YPEQKAANYIKQMAEALIYLHSKDIIHRDIKPEN-LLNSFG--TIKIADFGWSIHS-PSNKRQTICGTLDYLSPEMVEGNTHN-YTVDIWSLGVLCYEFC .| | . .|. .|. |.|||.|.|||||||| |. . | |||.|||.||. | .| | |||. | .||.... . . ||||||||. | LHEEEARRIFRQIVSAVNYCHSKNIVHRDIKPENILIDENGNHNIKIIDFGFSICIPPGQKLNTFCGTPPYMAPEIFLKKPYDGPKVDIWSLGVVLYFMV TGQPPFE--TKSYDQTYDRIKKVQFSFPDYLSIEVRDLLSKILVYEKSQRLDLNNILNHPWI .|. ||. |..| . | .| . ....|...| | |.|....|. ..| .. .|..|||. CGYFPFDGDTQDYKELYKKILRGKYDIPCHVSKECRNLIQRLLTVNPEERPTIEEIMKHPWM |
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| Kinase | 26122.AA | Pkinase | 85-336 | 29 | 7.4e-81 | 279.73 | Pfam | 1-293 (293) | Show / Hide |
Range on Protein: 85-336 Range on HMM: 1-293/293 Sequence Identity: 29% (87 aa) FELGKPLGRGKFGQVHLAREKRSNFIVALKCISKEQLRRSKIEHQIR-REIEIQSHLNHKNVLRMFGFFWDEQKIYLILEYAPQG----ELYQDLQKQIN ...|...|.| ||.| ....| .. |||.|.|.|. . .| .. .| .||.| .|||.|..|....| |...||...||.. | .|. .. . . YHIGRKIGSGSFGCVYKCHHKGTGKIVAVKIIKKRHEKSWKDQTHRRLSEIQIMKRLNHPNIVRLYDWFEDKDHIYMVMEYCEGGLYVMDLFDYISTWRH KRY--PEQKAANYIKQMAEALIYLHSKDIIHRDIKPENLLNS-FGTI----KIADFGWSI---HSPSNKRQTICGTLDYLSPEMVE-GNTHNYTVDIWSL ... .|. . .|..|....| |.||. |||||.||||.| . |.| ||.||| . . .. .|.|||..|..|| . |. . . ||.||. GCFYFSEWECKFYMYQILRGLEYCHSMGIIHRDLKPENILIDNNGHIDACVKICDFGLAKQFDY-NNS-MTTFCGTPWYMAPEVIRGGQYYGPKVDMWSC GVLCYEFCTGQPPFETK------SYDQTYDRIKKVQFSFPDYLS---------------------IEVRDLLSKILVYEKSQRLDLNNILNHPWI |...||...|.||| . . .| ..||.. ...|. . . | .|.....| . ..|. ||.|||. GCILYEMLCGRPPFPGHCWHDNHDQMQMICRIMGPPLHFDWPWWCSISYFFFRHWHFHWTFHNWSEECKDFIKWCLCKDPKKRPTAEQILQHPWF |
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| Kinase | 26122.AA | ULK | 85-336 | 30 | 5.2e-76 | 258.83 | In-house | 1-324 (324) | Show / Hide |
Range on Protein: 85-336
Range on HMM: 1-324/324
Sequence Identity: 30% (98 aa)
FELGKPLGRGKFG-QVHLAREKRS---NFIVALKCISKEQLRRSKIE-------HQIRREIEIQSHLN---HKN--VLRMFGFFWDE--QKIYLILEYAP
..| . || | || .|. .| |.. | .|| |.|.| ... .| | ....||.|. |. |.| . ... .|.. ||.|.|| .
YCLNHCLGKGSFGVKVYKGRNKKTNTQNQYVACKMIDKKKMNKKKNEQEGQYMWQLLKNEIQIMKKLKELKHPNHHIVKLYDWFETSNHNNIYIIMEYCN
QGELYQDLQKQIN-------KRYPEQKAANYIKQMAEALIYLHSKDIIHRDIKPENLL--NSF-----------GTIKIADFGWSIHSPSN-KRQTIC--
.| | | ..|. . || .||.| ...|| .... .||.. ||||||||.|.| | . |..|||||| . | .| . |..|
GGDLEQYIKKNKKLPETEEKKRLSEQEAIQFFKQICNGFKELHKHNIIHRDIKPQNILIHNGQPKTDSKKVHPNGVLKIADFGFAKHVDNNNMEQQMCQT
--------GTLDYLSPEMVEGN----THN-YTVDIWSLGVLCYEFCTGQPPFETKSYDQTYDR--------------IKKVQFSFPDY-----LSIEVRD
|| | .|. ..|. .. | .||||||.. || .|..||.. . ..|.. ||. .. ||.. .| |..|
CVNEKRIKGTPLYMAPQILQGQGEQKPYYDYKCDIWSLGCIFYEMLYGKYPFFSW-FNDQYLYIQKLINNGKEQQIYIKNQPIQFPKPPKDPKISPECKD
LLSKILVYEKSQRLDLNNILNHPWI
|... |.|. ..| . |.||||.
LIRRMLQYDEKDRISWEEIFNHPWF
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| Kinase | 26122.AA | ULK | 85-336 | 29 | 1.1e-75 | 257.75 | In-house | 1-329 (329) | Show / Hide |
Range on Protein: 85-336 Range on HMM: 1-329/329 Sequence Identity: 29% (97 aa) FELGKPLGRGKFGQVHLAREKRS----NFIVALKCISKEQLRRSKIEHQ-------IRREIEIQSHLN----HKN----VLRMFGFFWDE--QKIYLILE ..| . || | ||.|. .| |.. | .|| | |.|....... | . ...||.|. |. ||| . ... .|.. ||.|.| YCLNHCLGKGSFGKVYKGRNKKTKDYVNEKVACKMIDKQKMNQKNNEQEGQYMWQLLKNEIKIMKKLKSPNRHKNHHPNIVKLYDWFETSNHNNIYIIME YAPQGELYQDLQKQIN--------KRYPEQKAANYIKQMAEALIYLHSKDIIHRDIKPENLL--NSF-----------GTIKIADFGWSIHSPSN----- | ..| | | ..|. . || .||.| ...|| .... .||.. ||||||||.| | | . |..|||||| . | .. YCNGGDLEQYIKKNKKLPEDTEEKKRLSEQEAIQFFKQILNGFKELHKHNIIHRDIKPQNILIHNGQPKTDSKKVHPNGVLKIADFGFAKHVDNDNMEQQ KRQTIC------GTLDYLSPEMVEGN----THN-YTVDIWSLGVLCYEFCTGQPPFETKSYDQTY-----DR----------IKKVQFSFPDY-----LS .| || | .|. ..|. .. |..||||||.. || .|.|||.. . ..| . ||| .. ||.. .| MMMTCVNEKRLCGTPLYMAPQILQGQGEQKPYYDYKCDIWSLGCIFYEMLYGKPPFYAW-FNDQYLQIIQKLINNPPPWPQQIKKQPLQFPKDGNDPQIS IEVRDLLSKILVYEKSQRLDLNNILNHPWI |..||... |.|. ..| . ..||||. PECKDLIRRMLQYDEKDRISWEELFNHPWF |
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| Kinase | 26122.AA | PLK | 85-336 | 35 | 2.4e-75 | 244.82 | In-house | 1-258 (258) | Show / Hide |
Range on Protein: 85-336 Range on HMM: 1-258/258 Sequence Identity: 35% (93 aa) FELGKPLGRGKFGQVHLAREKRSNFIVALKCISKEQLRRSKIEHQIRREIEIQSHLNHKNVLRMFGFFWDEQKIYLILEYAPQGELYQDLQKQINKRYPE .| |..||.| | . ... .. ..| | ..|. . ... ...||||.. |.|.|.... || |.. .|. |||.....| ... |.. || | YERGHFLGKGGFAKCYEMTDIHTKQVYAIKVVPKSLMQKPHQREKMKQEIEIHRQLHHPNIVKFHHFFEDHENVYIVLEYCHNRSL-MHYHKRRAKRLTE QKAANYIKQMAEALIYLHSKDIIHRDIKPENL-LNSFGTIKIADFGWS--IHSPSNKRQTICGTLDYLSPEMVEGNT--HNYTVDIWSLGVLCYEFCTGQ . |. | ...| |||.. |||||.|. || ||. .||.||| . . . .. |.||| | .|| ..|| | | ||.||||. | . .|. PEVRYYMYQIVQGLKYLHQHRIIHRDLKLGNLFLNDNMHVKIGDFGLATRLEYDGERKKTMCGTPNYIAPEVLDGNKQGHSYEVDCWSLGCIMYTLLIGK PPFETKSYDQTYDRIKKVQFSFPDY--LSIEVRDLLSKILVYEKSQRLDLNNILNHPWI ||||||. .|| |||. ..|||.. .| | .||. |.| ..|. .. ||.||. PPFETKDVKETYKRIKHNHYSFPEHCPISDEAKDLIQKMLNWNPDERPTIDQILQHPFF |
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| Kinase | 26122.AA | Ciliate-E2-Unclassified | 85-336 | 26 | 2e-74 | 253.6 | In-house | 1-352 (352) | Show / Hide |
Range on Protein: 85-336
Range on HMM: 1-352/352
Sequence Identity: 26% (95 aa)
FELGKPLGRGKFGQVHLAREKRSNFIVALKCISKEQLRRSKIEHQ----IRREIEIQSH----------------LNHKNVLRMFGFFW--DEQKIYLIL
....| .|.| ||.|.....| ... |.| ..| | . .|. . .. ..|.... |||.. ... |.. |.|.||...
YKIIKQIGQGGFGKVYKCQHKKQKQYYAMKYMKKIQIYKQKQIMNKDEIMNEMKEMNNKKKYHQRKYNKIMQQILLNHPHPFIVKMFYCFQDKQNIYIVM
EYAPQGELYQDLQKQIN---------------KRYPEQKAA-----NYIKQMAEALIYLHSKD-IIHRDIKPENLLNSFG----TIKIADFGWSIHS---
||...|.| | ..|. . |. .||.|. .|..| ..| |||.| ||||||||||.| . . |||.||| |...
EYCEGGDLWQYIKKRKKQKQKGNDLFHNMKQRKIFTEQQAKYKKAKFYFAQILQGLEYLHHKNNIIHRDIKPENILFDNNGKNYYIKIIDFGISKKYQQN
--------------PSNKRQTICGTLDYL----SPEMVEGNTHN----YTVDIWSLGVLCYEFCTGQPPFETKSYDQ----------------TYDRIKK
.... .|.|||. |. .||. .|. .. | .|||||||..||...|..||. ....| |. ||.
NNCDTNQQQKMQIWKQQMMWTFCGTPNYMPQYTAPEVLQGQNYDHSKAYKCDIWSLGVILYEMLFGYYPFYDNNCEQHQQLITQWINNAYRKQLYQNIKQ
VQFSFP--------DYLSIEVRDLLS----KILVYEKSQRLDLNNILNHPWI
...|| . .| |. |... |.|.. ..|.... ||||||.
KNIQFPKFPWQQIPKHWSPEAKDFINDLLQKMLKKNPNKRITFEQILNHPWF
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| Kinase | 26122.AA | Pkinase_Tyr | 85-211 | 29 | 2.6e-23 | 79.56 | Pfam | 1-137 (270) | Show / Hide |
Range on Protein: 85-211 Range on HMM: 1-137/270 Sequence Identity: 29% (41 aa) FELGKPLGRGKFGQVHLAREK----RSNFIVALKCISKEQLRRSK-IEHQIRREIEIQSHL-NHKNVLRMFGFFW-DEQK--IYLILEYAPQGELYQDLQ ..|| ||.| ||.|.... | . || |.. ||. . . ||..| ..| .|.|..|. | ... ||...||.| | |. |. ITFGKKLGEGAFGEVYKGTWKGDPDNTKIPVAVKML-KEGAMHEQNCREDFMREAKIMKQLGHHPNIVRLYGVCTDQGEPNQIYIVMEYMPHGDLLDYLR KQ--INKRYPEQKAANYIKQMAEALIYLHSKDIIHRDI |. ... . . .. | |... ||.|| .||||. KHREDKQPLTMKDLLQMCWQIAKGMEYLESKNCIHRDL |
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| Kinase | 26122.AA | TyrKc | 85-336 | 23 | 5.1e-19 | 70.44 | SMART | 1-280 (280) | Show / Hide |
Range on Protein: 85-336 Range on HMM: 1-280/280 Sequence Identity: 23% (69 aa) FELGKPLGRGKFGQVHLAREKRSNFIVALKCISKEQLRRSKIEHQIRREIEIQSHL--NHKNVLRMFGFFWDE-------QKIYLILEYAPQGELYQDLQ .||| ||.| ||.|.... | || |.. .. . ..||..| ..| .|.|..|..| .. . .....||.| | | . |. ITLGKKLGEGAFGEVYKGTWK---IQVAVKMLKEDA------REDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPHGDLKDYLR KQINKRYPEQKAANYIKQMAEALIYLHSKDIIHRDIKPEN-LLNSFGTIKIADFGWSIHSPSN-------KRQTI----CGT----LDYLSPEMVEGNTH | .| . .. .. | |. ||||| .||||. | |... .|.||.||| | . . . .| . ..|| .. KHRPK-LCMKDLLSFCWQIACGMEYLHSKNCIHRDLAARNCLVGENHTVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGKTMLPIRWMAPECINYGKF NYTVDIWSLGVLCYEFCT-GQPPFET-----KSYDQTYDRIKKV-QFSFPDY--------LSIEVRDLLSKILVYEKSQRLDLNNILNHPWI . |.|| ||...| .| ||.| . .| .. . ..|. |.. . |. .. .. .. ..| ..| | . TTKSDVWSFGVCMWEIFTYGQQPYPGMIQQMMSNQEVIEYVKQGYRMPQPPNDYPMSFVCCPDEMYQIMKQCWHEDPEDRPTFSEI--HECF |
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| Kinase | 26122.AA | Pkinase_Tyr | 264-296 | 36 | 0.000658 | 13.86 | Pfam | 196-231 (270) | Show / Hide |
Range on Protein: 264-296 Range on HMM: 196-231/270 Sequence Identity: 36% (13 aa) DIWSLGVLCYEFCT-GQPP-FETKSYDQTYDRI-KK |.|| |||..| .| |. | .. | . |..| .. DVWSFGVLMWEIFTYGEQPTYPGMSNEEVYEYIYED |
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| Kinase | 26122.AA | Pkinase_Tyr | 216-229 | 42 | 0.97567 | 3.12 | Pfam | 143-156 (270) | Show / Hide |
Range on Protein: 216-229 Range on HMM: 143-156/270 Sequence Identity: 42% (6 aa) LLNSFGTIKIADFG |... ...||.||| LVTENNVVKICDFG |
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