Gene 3376 (Tetrahymena)

3376

Species: Tetrahymena
Alias: 404.m00007, 3376, 1121, PreTt03376, TTHERM_01466240
External Links: Tetrahymena Genome Database (TGD)
Annotation:

Classification

Group: Other
Family: Ciliate-A2

Sequence

Name Sequence Type Origin Length Description Download
3376.AA Protein None 571 None Fasta, JSON
3376.kin_dom Protein Kinase Domain None 261 None Fasta, JSON
3376.NA RNA None 1716 None Fasta, JSON

Protein domain

Protein domains of 3376.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Kinase 3376.AA Ciliate-A2 23-281 52 2.5e-154 518.99 In-house 1-272 (272) Show / Hide 
Range on Protein: 23-281
Range on HMM: 1-272/272
Sequence Identity: 52% (144 aa)

GQGSFGTVVFAEHI--ENKTQFAIKIIKIDGVLDQ-VSEQLLQEAKAEADFLKKQTHPNIVKYEDSFQIGLHYFIVMEKC-EKNLQQVIDEFEKSQSFIS
|||.||.|.|.||.  .|....||||..|... || .|.|.|||.|.||.|||...|||||||.|.||||..|||.|||| |..||..||.|...|.||.
GQGCFGCVIFVEHMDNHNNEKYAIKIQSIIDGIDQKISQQKLQECKHEAQFLKNCNHPNIVKYHDEFQIGFYYFIQMEKCPECSLQDWIDKFQNQQKFIP

KEQFVNYACQTLSAIKCLHEQNYLLRDLSLKNILIDSFNQ-IKLCDFGLVKKIQDEKNSKAYQQSQPKGAFYYYPPELLFQ-VHE---QEDNKKIIQDFN
..|||..|||.|.||..||..|| ||||||.|||||..|| ||||||||.||.|.|.||.....|.|||.|.|||||..|| ...   |.....|.|.|.
DHQFVHFACQILDAIEYLHNKNYVLRDLSLRNILIDQDNQIIKLCDFGLAKKYQPEINSQMFYTSCPKGVFFYYPPECHFQCFEMNGEQNKKQQIKQTFM

GDIWAFGICFFKLSGGN-INLPKLY---NKQEFLEKDKQQLDENLNQILLQILNYDINLRPKSIQEILLQFE
|||||||||...|.|.. ....||.   .|......|...|||..|||..||||.|...||.|||.|. ...
GDIWAFGICLYQLGGADQQHCYKLTQCNQKKWWQYQDYPNLDEKCNQIIQQILNCDPKKRPSSIQQIRHHWH
Kinase 3376.AA Ciliate-E6 68-220 37 1.6e-46 145.99 In-house 1-154 (154) Show / Hide 
Range on Protein: 68-220
Range on HMM: 1-154/154
Sequence Identity: 37% (58 aa)

ADFLKKQTHPNIVKYEDSFQIGLHYFIVMEKCEKNLQQVIDEFEKSQSFISKEQFVNYACQTLSAIKCLHEQNYLLRDLSLKNILIDSFNQIKLCDFGLV
...||   ||||.|| |||||   ||||||.||.|||..| . . ........||.. .||...|.  || .||.|  ..|||| .|    ||.||||. 
IQNLKNCNHPNILKYMDSFQIENYYFIVMERCEMNLQDWIHQHKNKKQINQNDQFFKFCCQLFHAVEYLHSKNYVLQNITLKNIFLDKNMNIKICDFGFQ

KKIQDEKNSKAYQQSQPKGAFYYYPPELLF-QVHEQEDNKKIIQDFNGDIWAFG
. |     .|... ...   . | |||..      |. ..|. .   ||||  .
QCIIPNQQTKEFMAQKNQNKYHYCPPEQFDYSKDQQSKHYKVNWTQEGDIWSVC
S_TKc 3376.AA S_TKc 16-281 22 1.9e-38 134.98 SMART 1-231 (231) Show / Hide 
Range on Protein: 16-281
Range on HMM: 1-231/231
Sequence Identity: 22% (64 aa)

KITNQVLGQGSFGTVVFAEHIENKTQFAIKIIKIDGVLDQVSEQLLQEAKAEADFLKKQTHPNIVKYEDSFQIGLHYFIVMEKCEK---NLQQVIDEFEK
    ...|.|.||.|  . |.. . ..||||||             . .. | . |||  ||||||. |.||   |...||| |.    .| ..|..  .
YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK-------------EHIRREIQILKK-HHPNIVKLYDVFQD-DHLYMVMEYCDGDLGDLFDYIKKRGR

--SQSFISKEQFVNYACQTLSAIKCLHEQNYLLRDLSLKNILIDSFNQIKLCDFGLVKKIQDEKNSKAYQQSQPKGAFYYYPPELLFQVHEQEDNKKIIQ
   .. ..  .   |..|...|.. .|... . |||   |||.|.  .||.||||| ...           .   |  .| .||.|              
HGLRFPFPE-HARFYMYQICCALEYCHSHGIIHRDLKPENILLDE--HIKICDFGLARQL-----------TTFCGTPWYMAPEVL--------------

DFNG---DIWAFGICFFKLSGGNI---NLPKLYNKQEFLEKDKQQLDENLNQILLQILNYDINLRPKSIQEIL-------LQFE
 ...   |.|..|.... .  |     .. ....|           .. . ... ..|..| . ||   .           .. 
GYGKCKCDWWSCGCILYEMLCGYPPFPQMQMMFKKIG---------SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF
Kinase 3376.AA Ciliate-E2 16-277 19 3.6e-34 114.7 In-house 1-360 (365) Show / Hide 
Range on Protein: 16-277
Range on HMM: 1-360/365
Sequence Identity: 19% (72 aa)

KITNQVLGQGSFGTVVFAEHIENKTQFAIKIIKIDG---------------VLDQVSEQLLQEAKAEADFLKKQT----------------HPNIVKYED
 . ....|||.||.|  ....... |||||||. .                 . ..... ... | | . ...                  ||||.|. .
YKFIKKIGQGNFGSVYKCKVWKVQKQFAIKIID-QKQQRQQMQEKVKIKIYAMKIMKKNQIEQIKQEIHIMREINCFYKKINEKNILEQLNHPNIIKMYE

SFQ--IGLHYFIVMEKCEK-NLQQVIDEF---------------EKSQSFISKEQFV-------NYACQTLSAIKCLHEQN-YLLRDLSLKNILIDSFNQ
.||     ....||| |.  .|.. | ..               ||  ..|.|...        .|... ..|.. ||..|  . ||. . |||.     
CFQEKDDNNIYLVMEYCQGGDLFDYIKNNKKKRNHEIEKDKYFTEKEIKYIMKQILQGFKTKAEFYIACIILALEYLHSKNNIIHRDIKPENILF-----

IKLCDFGLVKKIQDEKNSKAYQQSQPK----------------------------GAFYYYPPELLFQVHEQEDNKKIIQDFNGDIWAFGICFFKLSGGN
||..|||| ||..|. . . .  .| |                            |  .| .|| |    .. ..|.   |.  |||..|.... .  | 
IKIIDFGLSKKYDDDNQNRTH-KQQCKWYMFKNDTSRTPGYMDQIIQQNMFNTICGTPGYMAPEILNGKKYDNQQKQKGYDYKCDIWSLGVILYEMLFG-

INLPKLYNKQEFLEK----------------------DKQQLDENLNQILLQ----ILNYDINLRPKSIQEIL
 ..|     |.  ..                      ........  ... .    .|..| . |. ....||
-KPPF----QQQIKQCKIDFPCPEWQKDTQCIQCKWKSWKKWSQECKDLIKKFGKRMLQKDPEKRITGWEQIL
Kinase 3376.AA CAMK 21-196 18 3.2e-32 100.57 In-house 1-292 (425) Show / Hide 
Range on Protein: 21-196
Range on HMM: 1-292/425
Sequence Identity: 18% (55 aa)

VLGQGSFGTVVFAEHIENK------------TQFAIKIIKIDGVLDQV----------------------SEQLLQEAKAEADFLKKQT-------HPNI
.||.||||.|  ..|....            ...|||||. . . |..                      ... ... . | . .||         ||||
TLGRGSFGKVKLCIHKNTTGKERVHHIYTNGQKVAIKIIDKKKLKDKQNQDYSNCYKIDKSKCKHRYCWRRPKDRKNVRREIEIMKKLQGIGNKLDHPNI

VKYEDSFQ------------IGLH--------YFIVM---EKCEKN-----LQQVIDEFEKSQ-----------SFISKEQFVNYACQTLSAIKCLHEQN
.|  . ..               .        ...||   | |.       | . | | ..               .. ..   |  | .||.. .|..|
IKLYEVYEDPHYFKNTNDYET-SKQVFTKDKHMYMVMEIMEYCSGGELFDDLFDYIVEHGCYGEEFDQFDIVERGRFTEREARRYFRQICSAVHYCHSHN

YLLRDLSLKNILIDSF-----------------NQIKLCDFGLVKKIQDEKNSK-------------------AYQQSQPKGAFYYYP-PELL
   ||| . |||.|.                  |.||..|||. .|... .|..                       . . |  .| . ||.|
IVHRDLKPENILLDDNNDDSDPVEHDEIFDWNNNNIKIIDFGFANKFDPGENNFMCSDYKGGEMHNQWTTPTEGQKMKTFCGTPEYMAAPEVL
Kinase 3376.AA AGC 16-224 19 1e-30 75.32 In-house 1-296 (395) Show / Hide 
Range on Protein: 16-224
Range on HMM: 1-296/395
Sequence Identity: 19% (60 aa)

KITNQVLGQGSFGTVVFAEHI------ENKTQFAIKIIKIDG--VLDQ--VSEQLLQE--------AKAEADFLKKQT----------HPNIVK-YEDSF
     |.|.||||.|  ...        .. ..|.|..| .   |...    |. . |         ..| . |.|            ||.|||    ||
FEFLKVIGKGSFGKVYLVRKKDGCHKKDTGKYYAMKVLKKKHKIVIKKKNMVEHTMTEHWKQDQGYVWEERNILEKCNHTHNHPIKSHHPFIVKILHYSF

QIGLH--YFIVMEKCEKNLQQVI------D-EFEKSQS------FISKEQFVNYACQ-------TLSAIKCLHE-QNYLLRD-LSLKNILIDSFNQIKLC
|   |   ..||| ...    |       . |.  ..         . |.   ||..       ...|.  ||. ...  || | . |||.|.   |||.
QDKDHTYLYFVMEYMPR---YVNDLYCGGGCELFLHLQGRRKEGRFDEERARFYAAEMQKICGCIVLALEYLHSHMGIIHRDYLKPENILLDEDGHIKLT

DFGLVKKIQDEKNS----------------------------------------------KAYQQSQPKG--AFYYYPPELLFQVHEQEDNKKIIQDFNG
|||| |.. ....                                               |  . .   |     | .|| |              ..  
DFGLCKEGMNDGEKGQQSQSNMKFHWHNKKYQKSNMDTNKCNPNNWQRNNMSQEDDTTRKKRDRTWTFCGPCTPEYMAPEIL-------------YGKAC

DIWA--FGICFF
|.|.  .|....
DWWSFGLGCLMY
Kinase 3376.AA Pkinase 16-280 22 4.8e-30 107.33 Pfam 1-293 (293) Show / Hide 
Range on Protein: 16-280
Range on HMM: 1-293/293
Sequence Identity: 22% (71 aa)

KITNQVLGQGSFGTVVFAEHIENKTQFAIKIIKIDGVLDQVSEQL--LQEAKAEADFLKKQTHPNIVKYEDSFQIGLHYFIVMEKCEKNLQQVIDEF---
  . ...|.||||.|  . |. .  ..|.|||| ..  ... ...  |    .|.  .|.  |||||.. |.|. . |. .||| ||. |  |.| |   
YHIGRKIGSGSFGCVYKCHHKGTGKIVAVKIIKKRHEKSWKDQTHRRL----SEIQIMKRLNHPNIVRLYDWFEDKDHIYMVMEYCEGGLY-VMDLFDYI

--EKSQSF-ISKEQFVNYACQTLSAIKCLHEQNYLLRDLSLKNILIDSFNQI----KLCDFGLVKKIQDEKNSKAYQQSQPKGAFYYYPPELLFQVHEQE
  ... .|  | ..  .|. |.|.... .|... . ||| . |||||. ..|    |.||||| |...   . .    . . |  .| .||..       
STWRHGCFYFSEWECKFYMYQILRGLEYCHSMGIIHRDLKPENILIDNNGHIDACVKICDFGLAKQFD---Y-NNS-MTTFCGTPWYMAPEVIR------

DNKKIIQDFNGDIWAFGICFFKLSGGNINLPKL-----YNKQEFLEKDKQ-------QLD---------------------ENLNQILLQILNYDINLRP
  .    .   |.|..|. .. .  |.   |       ..... ......       . .                     |.. ...  .|..| . ||
--GGQYYGPKVDMWSCGCILYEMLCGRPPFPGHCWHDNHDQMQMICRIMGPPLHFDWPWWCSISYFFFRHWHFHWTFHNWSEECKDFIKWCLCKDPKKRP

KSIQEILLQ--F
 ....||    |
-TAEQILQHPWF
Kinase 3376.AA Ciliate-E2-Unclassified 17-277 20 3.7e-27 91.28 In-house 2-347 (352) Show / Hide 
Range on Protein: 17-277
Range on HMM: 2-347/352
Sequence Identity: 20% (72 aa)

ITNQVLGQGSFGTVVFAEHIENKTQF-----AIKIIKID-GVLDQVSEQLLQEAKAEAD---------------FLKKQTHPNIVKYEDSFQIGLHYFIV
. ....|||.||.|  ..|...| |.     ..||....     ..  ....|.|..                  |.   ||.|||... ||   . .||
KIIKQIGQGGFGKVYKCQHKKQK-QYYAMKYMKKIQIYKQKQIMNKD-EIMNEMKEMNNKKKYHQRKYNKIMQQILLNHPHPFIVKMFYCFQDKQNIYIV

MEKCE-KNLQQVIDEFEK-------------SQSFISKEQFV-----NYACQTLSAIKCLHEQN-YLLRDLSLKNILIDSFN---QIKLCDFGLVKKIQD
||.|| ..|.| | ...|             ..  .. .| .     .|. | |.... ||..|  . ||. . |||.|. .   .||..|||. ||.|.
MEYCEGGDLWQYIKKRKKQKQKGNDLFHNMKQRKIFTEQQAKYKKAKFYFAQILQGLEYLHHKNNIIHRDIKPENILFDNNGKNYYIKIIDFGISKKYQQ

EKNSKAYQ------------QSQPKGAFYYY----PPELLFQ-VHEQEDNKKIIQDFNGDIWAFGICFFKLSGGNINLPKLYNK----------------
  |.. ..            ...  |  .|     .||.| .  ....        .  |||..|.... .  |.  .|  .|.                
NNNCD-TNQQQKMQIWKQQMMWTFCGTPNYMPQYTAPEVLQGQNYDHSKA------YKCDIWSLGVILYEMLFGY--YPFYDNNCEQHQQLITQWINNAY

-QEFLEKDKQQ---------------LDENLNQILL----QILNYDINLRPKSIQEIL
 ...... ||.               ....   ..     ..|....| |. ....||
RKQLYQNIKQKNIQFPKFPWQQIPKHWSPEAKDFINDLLQKMLKKNPNKRI-TFEQIL
Kinase 3376.AA STE 17-173 21 9.4e-25 84.41 In-house 1-200 (359) Show / Hide 
Range on Protein: 17-173
Range on HMM: 1-200/359
Sequence Identity: 21% (45 aa)

ITN-QVLGQGSFGTVVFAEHI------ENKTQ---------FAIKIIKIDGV-----------LDQVSEQLLQEAKAEADFLKKQT--HPNIVKYEDSFQ
 .. ...|.|.||||. | ..      ... .         .|||.....             |... .. .|. . | ...||    ||||||| ... 
WEGIEKIGKGAFGTVYKAMNHKNCNIHKTGEVENNGETGEIMAIKQMNLENCNNKDENQENQELENKNHEEMQQILKEIKIMKKCNHMHPNIVKYYGCYF

IGL-------HYFIVMEKCE-KNLQQVID---EFEKSQS-------FISKEQFVNYACQTLSA-IKCLHEQNYLLRDLSLKNILIDSFNQIKLCDFGLVK
 .        . .|.|| ..   | ..|.   .  |...       ... .|   ...|.| .  . ||....  ||.   |||.     .||||||. .
KEGHNHKNDDELWICMEYMDGGSLDDIIKHKYGCGKPLNHNRQHQHRFPESQIAYICRQILKGLLYYLHSHHIIHRDIKPANILL-----VKLCDFGVCG

KIQDE
...|.
QLTDS
Kinase 3376.AA ULK 16-226 24 3.7e-24 82.65 In-house 1-245 (324) Show / Hide 
Range on Protein: 16-226
Range on HMM: 1-245/324
Sequence Identity: 24% (62 aa)

KITNQVLGQGSFG-TVVFAEHIEN---KTQFAIKIIKIDGVLDQVS----EQLLQEAKAEADFLKKQT---HPN--IVKYEDSFQIGLH--YFIVMEKCE
 . |..||.|||| .|  ......   . ..|.|.| ...  .. .    ....|  | |   .||     |||  |||. | |.   |  ..|.|| |.
YCLNHCLGKGSFGVKVYKGRNKKTNTQNQYVACKMIDKKKMNKKKNEQEGQYMWQLLKNEIQIMKKLKELKHPNHHIVKLYDWFETSNHNNIYIIMEYCN

K-NLQQVIDEFEK-----SQSFISKEQFVNYACQTLSAIKCLHEQNYLLRDLSLKNILIDSFN------------QIKLCDFGLVKKIQDEKNSKAYQQS
  .|.| | .  |      . ..| .. ...  | ... |.||..|.  ||. . ||||   .            ..|..|||. |.....  ..   |.
GGDLEQYIKKNKKLPETEEKKRLSEQEAIQFFKQICNGFKELHKHNIIHRDIKPQNILIHNGQPKTDSKKVHPNGVLKIADFGFAKHVDNNNMEQQMCQT

QP-----KGAFYYYPPELLFQV--HEQEDNKKIIQDFNGDIWAFGICFFKL
.      ||  .|  |..| .   ... ...|       ||| .|. |. .
CVNEKRIKGTPLYMAPQILQGQGEQKPYYDYK------CDIWSLGCIFYEM
Kinase 3376.AA TKL 22-224 17 3.3e-23 80.42 In-house 1-280 (364) Show / Hide 
Range on Protein: 22-224
Range on HMM: 1-280/364
Sequence Identity: 17% (50 aa)

LGQGSFGTVVFAEHIENK--------TQFAIKIIKIDGVL---------------------DQVSEQLLQEAKAEADFLKKQTHPNIVKYED-SFQIGL-
.|.|.||.|  ...  .         .  |.|..|.. .                      |. .... .. . |.  ...  |||||..   .....  
IGSGGFGEVYKGKWRGWGGKCPSDTGKDVAVKKFKSHNDDEFTKNSQENNDNNNYSDMQLNDPEASWFRFFEEEEIMMMSRLRHPNIVQFMGYCCCPPCG

-----------HYFIVMEKCEK-N-LQQVIDEFEKSQSFISKEQFVNYACQTLSAIKCLHEQN--------YLLRDLSLKNILIDSFNQ-----------
           ...|||| |.. . | ...            .|... | .. ...  || .|         . |||  ||||.|. ..           
CVCMHPVGPWGQLCIVMEYCPGGSLLHYLH-----------WHQRCRWALDIARGMNYLHSMNPKWCTKPPIIHRDLKSKNILVDENWTNVSNYMYNPNA

---IKLCDFGLVKKIQDEKNSKAY---------------QQSQPKGAFYYYPPELLFQVHEQEDN-------KKIIQDFNGDIWAFGICFF
   .|.||||| . .. ..|...                . . . | ... .||.| .  . ..        |.   .   |...|||...
DWCCKICDFGLSRFMSQSGNMNDTMTTMMESAEHQNNRKTTMTQCGTPRWMAPEVLRGQMNYTEKVGIDEFCKGFEYSEKCDVYSFGIVLW
Kinase 3376.AA NEK 16-179 27 7.3e-22 74.07 In-house 1-181 (286) Show / Hide 
Range on Protein: 16-179
Range on HMM: 1-181/286
Sequence Identity: 27% (50 aa)

KITNQVLGQGSFGTVVFAEHIENKTQ-----FAIKIIKIDGVLDQVSEQLLQEAKAEADFLKKQTHPNIVKYEDSFQIGL--HYFIVMEKCEK--NLQQV
    ...||||||.|  ....... .     ...| |....  ..  .....    |.  ||.  ||||||| |||.     . .|||| ||   .|.| 
YEIIKKIGQGSFGKVYKVRRKSDGKHLVEKLYVWKKINMGNMSEKEKQNAQN---NEVRILKQLKHPNIVKYYDSFIEEQNNCLCIVMEYCEGGGDLYQK

---IDEFEKSQSFISKEQFVNYACQTLSAIKCLHEQ-----NYLLRDLSLKNILIDSFNQ----IKLCDFGLVKKIQDEKNSKAY
   | .  ..  ... || ... .| ..|.|..|..     . | ||.  .|| ... |     .|. |||.  |... ....||
IKSIKKQKQKGKYFEEEQIWDWFIQMCLALKYMHDRKGPQRKILHRDIKPQNIFLTKNNNDYHNVKIGDFGIS-KVLNHTTDMAY
Kinase 3376.AA TyrKc 16-280 19 2.5e-12 -23.4 SMART 1-280 (280) Show / Hide 
Range on Protein: 16-280
Range on HMM: 1-280/280
Sequence Identity: 19% (59 aa)

KITNQVLGQGSFGTVVFAEHIENKTQFAIKIIKIDGVLDQVSEQLLQEAKAEADFLKKQ--THPNIVKYEDSFQIG-------LHYFIVMEKCEK-NLQQ
   ...|| | ||.|. .. .   .| |.| .| |          ...   ||  ..|    |||||.       .         ..|||| ... .|..
ITLGKKLGEGAFGEVYKGTWK---IQVAVKMLKEDA---------REDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPHGDLKD

VIDEFEKSQSFISKEQFVNYACQTLSAIKCLHEQNYLLRDLSLKNILIDSFNQIKLCDFGLVKKIQDE----KNSKAYQQS---QPK--GAFYYYPPELL
 . . ..    .. ....... |  .    ||..|.  |||   |.|... ...| .|||| ..| |.     ... | ..   . |       ..|| .
YLRKHRPK---LCMKDLLSFCWQIACGMEYLHSKNCIHRDLAARNCLVGENHTVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGKTMLPIRWMAPECI

FQVHEQEDNKKIIQDFNGDIWAFGICFF------KLSGGN-----INLPKLYNKQEFLEKDKQQLD----------ENLNQILLQILNYDINLRPKSIQE
         .. .  .  |.|.||.| .      .    .     ..   .... .  .  .|  .          . . || .|  ..| . || . .|
---------NYGKFTTKSDVWSFGVCMWEIFTYGQQPYPGMIQQMMSNQEVIEYVKQGYRMPQPPNDYPMSFVCCPDEMYQIMKQCWHEDPEDRP-TFSE

ILLQF
|  .|
IHECF
Kinase 3376.AA Pkinase_Tyr 136-173 39 1e-06 23.09 Pfam 127-164 (270) Show / Hide 
Range on Protein: 136-173
Range on HMM: 127-164/270
Sequence Identity: 39% (15 aa)

LHEQNYLLRDLSLKNILIDSFNQIKLCDFGLVKKIQDE
|...|.  |||  .|.|... |..| ||||| . |...
LESKNCIHRDLAARNCLVTENNVVKICDFGLARDIYND
Pkinase_Tyr 3376.AA Pkinase_Tyr 15-82 24 4.1e-05 17.94 Pfam 1-69 (270) Show / Hide 
Range on Protein: 15-82
Range on HMM: 1-69/270
Sequence Identity: 24% (18 aa)

LKITNQVLGQGSFGTVVFAEHI----ENKTQFAIKIIKIDGVLDQVSEQL--LQEAKAEADFLKKQ-THPNIVKY
...  ..||.|.||.|. ..      ..|.. |.|..|     .. ...   ...  .||  .|.   |||||..
ITFG-KKLGEGAFGEVYKGTWKGDPDNTKIPVAVKMLK-----EGAMHEQNCREDFMREAKIMKQLGHHPNIVRL
Kinase 3376.AA STE 215-283 13 0.06601 2.67 In-house 250-359 (359) Show / Hide 
Range on Protein: 215-283
Range on HMM: 250-359/359
Sequence Identity: 13% (15 aa)

DIWAFGICFFKLSGGNINLPKLYNKQ----------------------EFLEKDKQQLD-------------------ENLNQILLQILNYDINLRPKSI
||| .|..   .  |.  . .... .                      .   . .. |.                   ..... . . |..| | ||.. 
DIWSLGCTIIEMATGKPPWHDMHPMRAMFMIPFNYHMQQQFEQLCIVNGPPPPLPDHLSQNEMISYGGSGTTYPHKWSPEFKDFINKCLQKDPNKRPTAS

QEILLQ--FENI
|  ||.   . |
Q--LLKSEHPFI
TPR_1 3376.AA TPR_1 361-394 44 1e-07 30.95 Pfam 1-34 (34) Show / Hide 
Range on Protein: 361-394
Range on HMM: 1-34/34
Sequence Identity: 44% (15 aa)

HICYYNIGNAYLEIGLFDEAIKSYQEWLKFNPKI
   .||.||.|.. | .||||. ||. |. ||. 
AEAWYNLGNCYYKMGNYDEAIECYQKALELNPNN
TPR 3376.AA TPR 361-394 41 3.6e-07 31.07 SMART 1-34 (34) Show / Hide 
Range on Protein: 361-394
Range on HMM: 1-34/34
Sequence Identity: 41% (14 aa)

HICYYNIGNAYLEIGLFDEAIKSYQEWLKFNPKI
  ..||.||.|.  | .||||. ||. |. .|. 
AEAWYNLGNCYYKMGDYDEAIECYQKALELDPNN
TPR_2 3376.AA TPR_2 361-394 38 3.2e-05 22.56 Pfam 1-34 (34) Show / Hide 
Range on Protein: 361-394
Range on HMM: 1-34/34
Sequence Identity: 38% (13 aa)

HICYYNIGNAYLEIGLFDEAIKSYQEWLKFNPKI
  ..||.|..|.. | .||||. |.. || .|. 
AEAWYNLGQCYYKQGDYDEAIEYYEKALKLDPNN
TPR_1 3376.AA TPR_1 327-360 26 5.2e-05 21.49 Pfam 1-34 (34) Show / Hide 
Range on Protein: 327-360
Range on HMM: 1-34/34
Sequence Identity: 26% (9 aa)

DIFLFQQGYIQSQLKMFHAAIKSYQNCLKVNPNQ
   ... |... ... . .||. || .|..||| 
AEAWYNLGNCYYKMGNYDEAIECYQKALELNPNN
TPR 3376.AA TPR 327-360 23 0.000397 20.96 SMART 1-34 (34) Show / Hide 
Range on Protein: 327-360
Range on HMM: 1-34/34
Sequence Identity: 23% (8 aa)

DIFLFQQGYIQSQLKMFHAAIKSYQNCLKVNPNQ
   ....| .  ... .  ||. || .|...|| 
AEAWYNLGNCYYKMGDYDEAIECYQKALELDPNN
TPR_2 3376.AA TPR_2 327-360 23 0.005954 14.53 Pfam 1-34 (34) Show / Hide 
Range on Protein: 327-360
Range on HMM: 1-34/34
Sequence Identity: 23% (8 aa)

DIFLFQQGYIQSQLKMFHAAIKSYQNCLKVNPNQ
   ....| .  ... .  ||. |. .|| .|| 
AEAWYNLGQCYYKQGDYDEAIEYYEKALKLDPNN
TPR_2 3376.AA TPR_2 396-429 32 1e-06 27.74 Pfam 1-34 (34) Show / Hide 
Range on Protein: 396-429
Range on HMM: 1-34/34
Sequence Identity: 32% (11 aa)

FFGKYYLGIAYQNNKMFNEAIKMFLECLQLDPQH
. . |.|| .| ... . |||. . ..|.|||..
AEAWYNLGQCYYKQGDYDEAIEYYEKALKLDPNN
TPR 3376.AA TPR 396-429 32 4e-06 27.78 SMART 1-34 (34) Show / Hide 
Range on Protein: 396-429
Range on HMM: 1-34/34
Sequence Identity: 32% (11 aa)

FFGKYYLGIAYQNNKMFNEAIKMFLECLQLDPQH
    | || .| ... ..|||. . ..|.|||..
AEAWYNLGNCYYKMGDYDEAIECYQKALELDPNN
TPR_1 3376.AA TPR_1 400-429 33 5e-06 25.09 Pfam 5-34 (34) Show / Hide 
Range on Protein: 400-429
Range on HMM: 5-34/34
Sequence Identity: 33% (10 aa)

YYLGIAYQNNKMFNEAIKMFLECLQLDPQH
| || .| . . ..|||. . ..|.|.|..
YNLGNCYYKMGNYDEAIECYQKALELNPNN
TPR 3376.AA TPR 430-463 41 6e-06 27.09 SMART 1-34 (34) Show / Hide 
Range on Protein: 430-463
Range on HMM: 1-34/34
Sequence Identity: 41% (14 aa)

FNCNLNLGSAYYKIGQMDEAKKYYCKCQKLNQND
  . .||| .||| |. ||| ..| |. .|. |.
AEAWYNLGNCYYKMGDYDEAIECYQKALELDPNN
TPR_1 3376.AA TPR_1 435-463 51 8.6e-05 20.72 Pfam 6-34 (34) Show / Hide 
Range on Protein: 435-463
Range on HMM: 6-34/34
Sequence Identity: 51% (15 aa)

NLGSAYYKIGQMDEAKKYYCKCQKLNQND
||| .||| |. ||| ..| |. .|| |.
NLGNCYYKMGNYDEAIECYQKALELNPNN
TPR_2 3376.AA TPR_2 430-463 47 0.000492 18.36 Pfam 1-34 (34) Show / Hide 
Range on Protein: 430-463
Range on HMM: 1-34/34
Sequence Identity: 47% (16 aa)

FNCNLNLGSAYYKIGQMDEAKKYYCKCQKLNQND
. .  ||| .||| |. |||..|| |. ||. |.
AEAWYNLGQCYYKQGDYDEAIEYYEKALKLDPNN
TPR_2 3376.AA TPR_2 471-504 38 0.000424 18.59 Pfam 1-34 (34) Show / Hide 
Range on Protein: 471-504
Range on HMM: 1-34/34
Sequence Identity: 38% (13 aa)

FICLYNLGNIYYRQHMYLEAIQKYNECENLYSIL
. ..||||..||.|  | |||. |...  |.   
AEAWYNLGQCYYKQGDYDEAIEYYEKALKLDPNN
TPR 3376.AA TPR 471-504 38 0.001271 19.28 SMART 1-34 (34) Show / Hide 
Range on Protein: 471-504
Range on HMM: 1-34/34
Sequence Identity: 38% (13 aa)

FICLYNLGNIYYRQHMYLEAIQKYNECENLYSIL
  ..|||||.||..  | |||. |...  |    
AEAWYNLGNCYYKMGDYDEAIECYQKALELDPNN
TPR_1 3376.AA TPR_1 471-497 44 0.002543 15.58 Pfam 1-27 (34) Show / Hide 
Range on Protein: 471-497
Range on HMM: 1-27/34
Sequence Identity: 44% (12 aa)

FICLYNLGNIYYRQHMYLEAIQKYNEC
   .|||||.||..  | |||. |...
AEAWYNLGNCYYKMGNYDEAIECYQKA
TPR_1 3376.AA TPR_1 524-554 41 6.9e-07 28.02 Pfam 4-34 (34) Show / Hide 
Range on Protein: 524-554
Range on HMM: 4-34/34
Sequence Identity: 41% (13 aa)

YYNLGSAYLKVKKHLESIKNYEKCIQLNKNH
.|||| .|.| ... | |. |.|...|| |.
WYNLGNCYYKMGNYDEAIECYQKALELNPNN
TPR_2 3376.AA TPR_2 521-554 38 2.8e-05 22.78 Pfam 1-34 (34) Show / Hide 
Range on Protein: 521-554
Range on HMM: 1-34/34
Sequence Identity: 38% (13 aa)

QSSYYNLGSAYLKVKKHLESIKNYEKCIQLNKNH
   .|||| .|.| ... | |. |||...|. |.
AEAWYNLGQCYYKQGDYDEAIEYYEKALKLDPNN
TPR 3376.AA TPR 521-554 35 2.9e-05 24.72 SMART 1-34 (34) Show / Hide 
Range on Protein: 521-554
Range on HMM: 1-34/34
Sequence Identity: 35% (12 aa)

QSSYYNLGSAYLKVKKHLESIKNYEKCIQLNKNH
   .|||| .|.| ... | |. |.|...|. |.
AEAWYNLGNCYYKMGDYDEAIECYQKALELDPNN