Gene 11522 (Tetrahymena)

11522

Species: Tetrahymena
Alias: PreTt11522, 1.m00570, 945, 11522, TTHERM_00001150
External Links: Tetrahymena Genome Database (TGD)
Annotation:

Classification

Group: Other
Family: Ciliate-A7

Sequence

Name Sequence Type Origin Length Description Download
11522.AA Protein None 423 None Fasta, JSON
11522.kin_dom Protein Kinase Domain None 203 None Fasta, JSON
11522.NA RNA None 1272 None Fasta, JSON

Protein domain

Protein domains of 11522.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Kinase 11522.AA Ciliate-A7 260-411 30 4.8e-72 245.67 In-house 167-360 (360) Show / Hide 
Range on Protein: 260-411
Range on HMM: 167-360/360
Sequence Identity: 30% (59 aa)

KVTRDDDGVQYYLGDFAYSKECGFTSQKE----------AKRFFQQKVQSYFSPEIFALIEG--------------GQIDLQNFEKQ--YDVFAFGISLF
............|.||...|...|.|..|          ...........||.|||......              .||| |.....  .||||||.|.|
CNNNQQNQYCFKLADFGFAKKYQFQSHFESTLRQQIIEDQYKNWKYRCKQYFAPEIINCLNKCCDKNSAKNKKFISQQIDNQCEFDEKKCDVFAFGVSFF

QILFQMNPFQSNGCHLSDTS-FNLLHTNPEK---FWSQLWQPLSVYG------------QMTNIDLMKDLLTKMLERDPSKRPNISQILQHPWL
|||||.|||....||..|.. ..........   .|.|.........            |...||.|||||.|||...||.|..|.|||||||.
QILFQQNPFCCEACHQNDPYKYKHYFQKTYSKFWQWMQIQWMWNHFQKEIQDMIKNTDQQQQDIDQMKDLLNKMLCPNPSQRYCIKQILQHPWF
Kinase 11522.AA Ciliate-E2 219-411 21 3.3e-22 73.04 In-house 172-365 (365) Show / Hide 
Range on Protein: 219-411
Range on HMM: 172-365/365
Sequence Identity: 21% (52 aa)

ALKYLHEELNIAHNDIKPDNFFAHFGQHPLIESSQVYDYTNKVTRDDDGVQYYLGDFAYSKECGFTSQKEAKRFFQQK----------------------
||.|||.. || | ||||.| .                               . || .||..   .|.. . . |.|                      
ALEYLHSKNNIIHRDIKPENILF----------------------------IKIIDFGLSKKYDDDNQNRTH-KQQCKWYMFKNDTSRTPGYMDQIIQQN

-------VQSYFSPEIFALIE-GGQIDLQNFEKQYDVFAFGISLFQILFQMNPFQSNGCHLSDTSFNLLHTNPEKFWSQLWQ--PLSVYGQMTNI-----
          | .|||.   . ..|.. .   .. |....|. |.. ||   ||           ..  . .. .| .. ||   .    | ...     
MFNTICGTPGYMAPEILNGKKYDNQQKQKGYDYKCDIWSLGVILYEMLFGKPPF-----------QQQIKQCKIDFPCPEWQKDTQ-CI-Q-CKWKSWKK

--DLMKDLLTK----MLERDPSKRPN-ISQILQHPWL
  . .|||. |    ||..||.||.. ..|||.|||.
WSQECKDLIKKFGKRMLQKDPEKRITGWEQILNHPWF
Kinase 11522.AA CAMK1 385-411 51 1.1e-16 45.02 In-house 250-276 (276) Show / Hide 
Range on Protein: 385-411
Range on HMM: 250-276/276
Sequence Identity: 51% (14 aa)

KDLLTKMLERDPSKRPNISQILQHPWL
||....||| ||.||....|.|.|||.
KDFIKHMLEVDPKKRYTCEQCLNHPWI
Kinase 11522.AA CAMK 385-411 59 5.5e-15 44.04 In-house 399-425 (425) Show / Hide 
Range on Protein: 385-411
Range on HMM: 399-425/425
Sequence Identity: 59% (16 aa)

KDLLTKMLERDPSKRPNISQILQHPWL
|||. |||..||.||..|.|.|.|||.
KDLIRKMLQVDPEKRMTIEQCLNHPWM
Kinase 11522.AA Ciliate-E2-Unclassified 317-411 25 4e-14 45.42 In-house 241-352 (352) Show / Hide 
Range on Protein: 317-411
Range on HMM: 241-352/352
Sequence Identity: 25% (30 aa)

QNFE----KQYDVFAFGISLFQILFQMNPFQSNGCHLSDT-------------SFNLLHTNPEKFWSQLW----QPLSVYGQMTNIDLMKDLLTKMLERD
|| .    .. |....|. |...||.  ||..| |  ...              ..  . .. .| .. |    . .|  ..    |. .||| |||. .
QNYDHSKAYKCDIWSLGVILYEMLFGYYPFYDNNCEQHQQLITQWINNAYRKQLYQNIKQKNIQFPKFPWQQIPKHWSPEAK----DFINDLLQKMLKKN

PSKRPNISQILQHPWL
|.||....|||.|||.
PNKRITFEQILNHPWF
Kinase 11522.AA CAMKL 385-411 55 5e-14 41.02 In-house 271-297 (297) Show / Hide 
Range on Protein: 385-411
Range on HMM: 271-297/297
Sequence Identity: 55% (15 aa)

KDLLTKMLERDPSKRPNISQILQHPWL
.||. |||...|.|||.| ||..|||.
RDLIRKMLQVNPEKRPTIHQIMNHPWM
Kinase 11522.AA LKB 384-411 39 4e-13 35.36 In-house 238-265 (265) Show / Hide 
Range on Protein: 384-411
Range on HMM: 238-265/265
Sequence Identity: 39% (11 aa)

MKDLLTKMLERDPSKRPNISQILQHPWL
. .|...||. |..||... || .|||.
LQNLIKGMLQYDHNKRFSCHQIMHHPWF
Kinase 11522.AA Pkinase 324-411 23 6.5e-13 46.74 Pfam 194-293 (293) Show / Hide 
Range on Protein: 324-411
Range on HMM: 194-293/293
Sequence Identity: 23% (24 aa)

DVFAFGISLFQILFQMNPFQSNGCHLSDTSFNLLHTNPEKFW----SQLWQPLSVYGQMTNI-----------DLMKDLLTKMLERDPSKRPNISQILQH
|....|. |.. |.   ||. . |  .|.  . ..   .. .    .. ... |..  ....           . .||.....|..||.|||.. |||||
DMWSCGCILYEMLCGRPPFP-GHC-WHDN-HDQMQMICRIMGPPLHFDWPWWCSISYFFFRHWHFHWTFHNWSEECKDFIKWCLCKDPKKRPTAEQILQH

PWL
||.
PWF
Kinase 11522.AA Ciliate-E9 385-411 40 1.4e-11 32.89 In-house 272-298 (298) Show / Hide 
Range on Protein: 385-411
Range on HMM: 272-298/298
Sequence Identity: 40% (11 aa)

KDLLTKMLERDPSKRPNISQILQHPWL
.|..  ||..|| .|. | .|  |||.
IDMMNWMLQQDPQNRISIQEIRMHPWM
Kinase 11522.AA Ciliate-A7 215-240 69 2.2e-11 37.59 In-house 139-164 (360) Show / Hide 
Range on Protein: 215-240
Range on HMM: 139-164/360
Sequence Identity: 69% (18 aa)

EIGTALKYLHEELNIAHNDIKPDNFF
.|. ||.|||.|.|||||||||.| |
QIAQALHYLHNEKNIAHNDIKPENIF
Kinase 11522.AA RAD53 385-411 51 3e-11 29.24 In-house 279-305 (305) Show / Hide 
Range on Protein: 385-411
Range on HMM: 279-305/305
Sequence Identity: 51% (14 aa)

KDLLTKMLERDPSKRPNISQILQHPWL
|||  .||  || ||..| ..|.|||.
KDLIKWMLCVDPEKRYTIDEALNHPWM
S_TKc 11522.AA S_TKc 130-411 14 9.3e-11 -19.12 SMART 1-231 (231) Show / Hide 
Range on Protein: 130-411
Range on HMM: 1-231/231
Sequence Identity: 14% (47 aa)

FVITQNI---------SCKNAN-----IAKPIDFKATPARCMLFSPYMSEKDAFTHLIQKNAGIFQKINYFS-------LENRSN---EQDELLHRVRG-
. | . |          |.. .       | |.              ..| .   .   .   | . . .|        .|  ..   .  ..... .. 
YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK-----------EHIRREIQILKK---HHPNIVKLYDVFQDDHLYMVMEYCDGDLGDLFDYIKKRGRH

------ILFGAMKLAFEIGTALKYLHEELNIAHNDIKPDNFFAHFGQHPLIESSQVYDYTNKVTRDDDGVQYYLGDFAYSKECGFTSQKEAKRFFQQKVQ
          | ... .|  ||.|.|.  .| | |.||.| .                            .  ..||  ...                . 
GLRFPFPE-HARFYMYQICCALEYCHSH-GIIHRDLKPENILLDE-------------------------HIKICDFGLARQL------------TTFCG

S--YFSPEIFALIEGGQIDLQNFEK-QYDVFAFGISLFQILFQMNPFQSNGCHLSDTSFNLLHTNPEKFWSQLWQPLSVYGQMTNIDLMKDLLTKMLERD
.  | .||..            . |   |. ..|. |.  |    ||.    ..  .  ...                        . .||.. |.|..|
TPWYMAPEVL-----------GYGKCKCDWWSCGCILYEMLCGYPPFP----QMQMMFKKIG-----------------------SPEAKDFIRKCLQKD

PSKRPNISQILQ-------HPWL
|.||| . ..||       |||.
PEKRPTA-EALQDEWDIKCHPWF
Kinase 11522.AA MAPKAPK 385-411 51 1.9e-09 24.94 In-house 266-292 (292) Show / Hide 
Range on Protein: 385-411
Range on HMM: 266-292/292
Sequence Identity: 51% (14 aa)

KDLLTKMLERDPSKRPNISQILQHPWL
|||  |.| |||..|  | |...|||.
KDLIRKLLRRDPTQRLTIEQVMNHPWI
Kinase 11522.AA MAPKAPK 215-238 50 1e-06 16.26 In-house 111-133 (292) Show / Hide 
Range on Protein: 215-238
Range on HMM: 111-133/292
Sequence Identity: 50% (12 aa)

EIGTALKYLHEELNIAHNDIKPDN
.|..|...|| ..|||| |.|| |
DICSAVDFLH-SMNIAHRDLKPEN
Kinase 11522.AA RAD53 218-238 52 1e-05 12.45 In-house 120-139 (305) Show / Hide 
Range on Protein: 218-238
Range on HMM: 120-139/305
Sequence Identity: 52% (11 aa)

TALKYLHEELNIAHNDIKPDN
.|.|||| ...|.| |.||.|
DAVKYLH-DNGICHRDLKPEN
Kinase 11522.AA Ciliate-E2-Unclassified 219-238 60 1.5e-05 15.21 In-house 155-174 (352) Show / Hide 
Range on Protein: 219-238
Range on HMM: 155-174/352
Sequence Identity: 60% (12 aa)

ALKYLHEELNIAHNDIKPDN
.|.|||...|| | ||||.|
GLEYLHHKNNIIHRDIKPEN
Kinase 11522.AA Ciliate-E9 219-238 45 0.000266 9.22 In-house 123-142 (298) Show / Hide 
Range on Protein: 219-238
Range on HMM: 123-142/298
Sequence Identity: 45% (9 aa)

ALKYLHEELNIAHNDIKPDN
.  |.| . || | |.||.|
SIEYMHQYQNICHRDLKPEN
Pkinase 11522.AA Pkinase 211-240 33 0.000538 15.21 Pfam 112-140 (293) Show / Hide 
Range on Protein: 211-240
Range on HMM: 112-140/293
Sequence Identity: 33% (10 aa)

KLAFEIGTALKYLHEELNIAHNDIKPDNFF
. . .|  .|.|.|.  .| | |.||.|..
FYMYQILRGLEYCHS-MGIIHRDLKPENIL
Kinase 11522.AA CAMKL 219-238 50 0.003324 5.91 In-house 139-157 (297) Show / Hide 
Range on Protein: 219-238
Range on HMM: 139-157/297
Sequence Identity: 50% (10 aa)

ALKYLHEELNIAHNDIKPDN
|..|.|.   |.| ||||.|
AVNYCHSHG-IVHRDIKPEN
Kinase 11522.AA CAMK 216-238 43 0.014812 3.25 In-house 188-209 (425) Show / Hide 
Range on Protein: 216-238
Range on HMM: 188-209/425
Sequence Identity: 43% (10 aa)

IGTALKYLHEELNIAHNDIKPDN
|  |..|.|.   |.| |.||.|
ICSAVHYCHSHN-IVHRDLKPEN
Kinase 11522.AA CAMK1 219-238 45 0.014892 3.17 In-house 120-138 (276) Show / Hide 
Range on Protein: 219-238
Range on HMM: 120-138/276
Sequence Identity: 45% (9 aa)

ALKYLHEELNIAHNDIKPDN
|..|.| ...|.| |.|| |
AVEYMH-SKGIVHRDLKPEN
Kinase 11522.AA LKB 219-238 45 0.01528 3.43 In-house 116-134 (265) Show / Hide 
Range on Protein: 219-238
Range on HMM: 116-134/265
Sequence Identity: 45% (9 aa)

ALKYLHEELNIAHNDIKPDN
.. |||    . | ||||.|
GCEYLHSQ-RVVHKDIKPGN