Gene 20983 (Tetrahymena)

20983

Species: Tetrahymena
Alias: 31.m00285, 624, TTHERM_00316830, 3687.m00087, PreTt20983, 20983
External Links: Tetrahymena Genome Database (TGD)
Annotation:

Classification

Group: Other
Family: Ciliate-A9

Sequence

Name Sequence Type Origin Length Description Download
20983.AA Protein None 932 None Fasta, JSON
20983.kin_dom Protein Kinase Domain None 252 None Fasta, JSON
20983.NA RNA None 2799 None Fasta, JSON

Protein domain

Protein domains of 20983.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Kinase 20983.AA Ciliate-A9 92-343 38 1.8e-237 575.49 In-house 1-392 (392) Show / Hide 
Range on Protein: 92-343
Range on HMM: 1-392/392
Sequence Identity: 38% (152 aa)

FLPIKILGSGAFGKVVQAREIK--TKKEYAVKIIAKNNVSNGEIDRLRKEAKILSQLDHKNIVKFE---------------------RVFESETRIFIVM
|.||||.|.||||.|.|.|.|.  .|.|||||.|.||......|.....|||||.|.||.|||||.                     ...||...|.|||
FEPIKIIGEGAFGCVIQCRDIQQEDKQEYAVKVIQKNKMKMDCIEFQDQEAKILQQHDHPNIVKFKNIKNINTQKETKQLNYIFQISKFCESDQNIHIVM

ELLLGGTLRQLMSERKKSKQWFTEQEAAQIMNNIINGVAYFHGKSIVHRDLKPD----------------------------------------------
|....|||.|||.||||..|||.|||..|||..|...|.|.|.|.|.|||||||                                              
EYMKCGTLQQLMKERKKNNQWFNEQEISQIMKCIMSAVMYMHQKNICHRDLKPDRQINKCIQLFISSFIHLFINHHNYCKQQNKQTNKQTNEKINQVKIF

----NILIGDKNDLDTVKIADFGLSA---------AFEAKKSISFTQQCGTLIYMAPEFFIQKTYSK---------------------------------
    ||||||||||..|||||||||.         .|......|..|||||||||||||||.|.||.                                 
ILTENILIGDKNDLTQVKIADFGLSKSFVKSQRVQYFTQWTYHSMYQQCGTLIYMAPEFFINKQYSQPVDHAVSMKSRKRLIYLFLQLIILFLNSLKSQN

-----------------------LLCHGTHPLYDP--LVDDNKSFKNKIQKNPQIQFPSCFSDITKNLIQKMTLIDPSARYTANQVIYHPWI
                       |||.|.||...|  ..||...||.|||.|||..|....|...||.|||||.|.||.||.|.|...||||
QFILYRQFKQQVDMWSCGIIMYMLLCMGKHPFWCPYEKNDDEDYFKMKIQCNPQWEFWDNCSNNAKNFIQKMTNINPSNRYNAFQCLKHPWI
Kinase 20983.AA S_TKc 92-343 30 6.5e-71 242.82 SMART 1-231 (231) Show / Hide 
Range on Protein: 92-343
Range on HMM: 1-231/231
Sequence Identity: 30% (84 aa)

FLPIKILGSGAFGKVVQAREIKTKKEYAVKIIAKNNVSNGEIDRLRKEAKILSQLDHKNIVKFERVFESETRIFIVMELLLG--GTLRQLMSERKKSK--
.  ....|.|||||| ..|..||....|.|||          ...|.| .||.. .|.||||.  ||.. .....|||.. |  |.|.... .|.. .  
YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK---------EHIRREIQILKK-HHPNIVKLYDVFQD-DHLYMVMEYCDGDLGDLFDYIKKRGRHGLR

QWFTEQEAAQIMNNIINGVAYFHGKSIVHRDLKPDNILIGDKNDLDTVKIADFGLSAAFEAKKSISFTQQCGTLIYMAPEFFIQKTYSK-----------
..|.| .|. .|  |.....| | . |.||||||.|||. .     ..||.||||.. .        | .|||. ||||| .    |.|           
FPFPE-HARFYMYQICCALEYCHSHGIIHRDLKPENILLDE-----HIKICDFGLARQL--------TTFCGTPWYMAPEVL---GYGKCKCDWWSCGCI

---LLCHGTHPLYDPLVDDNKSFKNKIQKNPQIQFPSCFSDITKNLIQKMTLIDPSARYTANQVIY-------HPWI
   .|| |  | .    .... ||.              |.  |..|.|.   ||. |.|| ..         |||.
LYEMLC-GYPPFP----QMQMMFKKIG------------SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF
Kinase 20983.AA CAMK1 92-276 36 4.9e-65 187.97 In-house 1-195 (276) Show / Hide 
Range on Protein: 92-276
Range on HMM: 1-195/276
Sequence Identity: 36% (73 aa)

FLPIKILGSGAFGKVVQAREIKT---KKEYAVKIIA-KNNVSNGEI---DRLRKEAKILS---QLDHKNIVKFERVFESETRIFIVMELLLGGTLRQLMS
.  .|..|.|||..|... ...|   .|.||.|.|  | .... .    ..|..|  |.    ..|| ||.||. ..||.. . .||||. || |     
YEFGKEIGRGAFSEVYLCTHKETQTNGKQYAIKCIDKKKFMKKKDMQKQEALENEIEIMKKVSKIDHPNIIKFYEWYESDNHFYLVMELVTGGELFDRIV

ERKKSKQWFTEQEAAQIMNNIINGVAYFHGKSIVHRDLKPDNILIGDKNDLDTVK--IADFGLSAAFEAKK-SISFTQQCGTLIYMAPEFFIQ---KTYS
|..     .||..|. || .|.  | | | | |||||||| |.|  || .  ..|  |||||||  |. .    .  ..|||. |.||| . .   | |.
EKG----NYTEKDARHIMKQILSAVEYMHSKGIVHRDLKPENLLYYDKDEDSKIKRSIADFGLSKIFDHDENLMK--TACGTPGYVAPEVLECKKDKPYD

K
|
K
Kinase 20983.AA Ciliate-E2 92-343 23 1.4e-64 220.65 In-house 1-365 (365) Show / Hide 
Range on Protein: 92-343
Range on HMM: 1-365/365
Sequence Identity: 23% (90 aa)

FLPIKILGSGAFGKVVQAREIKTKKEY------------------AVKIIAKNNVSNGEIDRLRKEAKIL----------------SQLDHKNIVKFERV
.  ||..|.|.||.| ... .|..|..                  ..||.|...... .|  . .| .|.                .||.|.||.|.  .
YKFIKKIGQGNFGSVYKCKVWKVQKQFAIKIIDQKQQRQQMQEKVKIKIYAMKIMKKNQIEQIKQEIHIMREINCFYKKINEKNILEQLNHPNIIKMYEC

FE--SETRIFIVMELLLGGTLRQLMSER-KKSKQW------FTEQEAAQIMNNIIN---------------GVAYFHGKS-IVHRDLKPDNILIGDKNDL
|.  ... |..|||.. ||.|.... .. ||...       |||.|...||  |..               .. | | |  |.|||.||.|||.      
FQEKDDNNIYLVMEYCQGGDLFDYIKNNKKKRNHEIEKDKYFTEKEIKYIMKQILQGFKTKAEFYIACIILALEYLHSKNNIIHRDIKPENILF------

DTVKIADFGLS-----------------AAFEAKKSISFTQQ--------------CGTLIYMAPEFFIQKT---------YS------------KLLCH
  .||.|||||                    . |  .| |.               |||. ||||| .  |          |.              .. 
--IKIIDFGLSKKYDDDNQNRTHKQQCKWYMF-KNDTSRTPGYMDQIIQQNMFNTICGTPGYMAPEILNGKKYDNQQKQKGYDYKCDIWSLGVILYEMLF

GTHPLYDPLVDDNKSFKNKIQKNPQIQFPSC------------------FSDITKNLIQK----MTLIDPSARYT-ANQVIYHPWI
| .|              ...|. .|.||.                    |. .|.||.|    |   ||. |.| ..|.. |||.
GKPPF------------QQQIKQCKIDFPCPEWQKDTQCIQCKWKSWKKWSQECKDLIKKFGKRMLQKDPEKRITGWEQILNHPWF
Kinase 20983.AA Ciliate-E2a 92-267 36 2.8e-64 188.12 In-house 1-180 (275) Show / Hide 
Range on Protein: 92-267
Range on HMM: 1-180/275
Sequence Identity: 36% (68 aa)

FLPIKILGSGAFGKVVQAREIKTKKEYAVKIIAKNNVSNGEIDR--LRKEAKILSQLDHKNIVKFERVFESETRIFIVMELLLGGTLRQLMSERKKSKQW
.  ||..|.|.||.|. |. ..|.|..|.|.. |   .. ....  . .| .|..||||.|| |.  |.|.|. ...|||.. ||.| . .   |..|. 
YKFIKKIGKGNFGSVYLAQHKQTGKQFAMKKFIK-KMYQQKKGKEYFMNEINIMRQLDHPNIIKLYEVYEDENNYYLVMEYCEGGELYDKI---KQCKRF

FTE-QEAAQIMNNII-NGVAYFHGKSIVHRDLKPDNILIG--DKND--LDTVKIADFGLSAAFEAKKSISFTQQCGTLIYMAPE
|.| ||...|| ...  |..|.| . |.||||||.|||.   .||.  .  .||.||||.  .  ..     |.|||  |.|||
FEEIQEICDIMQQLLWQGLHYMHQRNIMHRDLKPENILFKNCSKNSIQNSDIKIIDFGLATFIDKDEKKYMFQKCGTPGYVAPE
Kinase 20983.AA CAMK 97-274 22 1.8e-60 193.24 In-house 1-310 (425) Show / Hide 
Range on Protein: 97-274
Range on HMM: 1-310/425
Sequence Identity: 22% (70 aa)

ILGSGAFGKVVQAREIKTK------------KEYAVKIIAKNNVSNGE--------------------------IDRLRKEAKILSQ-------LDHKNI
.||.|.||||  .....|.            ...|.||| |. ... .                           ...|.| .|...       |||.||
TLGRGSFGKVKLCIHKNTTGKERVHHIYTNGQKVAIKIIDKKKLKDKQNQDYSNCYKIDKSKCKHRYCWRRPKDRKNVRREIEIMKKLQGIGNKLDHPNI

VKFERVFES-------------------ETRIFIVM---ELLLGG----TLRQLMSERKK----------SKQW--FTEQEAAQIMNNIINGVAYFHGKS
.|.  |.|.                   ......||   |.  ||     | .   |...            ..  |||.||....  |. .|.| | . 
IKLYEVYEDPHYFKNTNDYETSKQVFTKDKHMYMVMEIMEYCSGGELFDDLFDYIVEHGCYGEEFDQFDIV-ERGRFTEREARRYFRQICSAVHYCHSHN

IVHRDLKPDNILIGDKNDLD--------------TVKIADFGLSAAFEAKK----------------------SISFTQQCGTLIYMA-PEFFIQ-----
||||||||.|||. |.|| .              ..||.|||... |. ..                         .. .|||. ||| || . .     
IVHRDLKPENILLDDNNDDSDPVEHDEIFDWNNNNIKIIDFGFANKFDPGENNFMCSDYKGGEMHNQWTTPTEGQKMKTFCGTPEYMAAPEVLNGKGHCN

--------KTY
        |.|
MQNATDEEKPY
Kinase 20983.AA CAMKL 92-274 30 4.3e-57 180.68 In-house 1-212 (297) Show / Hide 
Range on Protein: 92-274
Range on HMM: 1-212/297
Sequence Identity: 30% (66 aa)

FLPIKILGSGAFGKVVQAREIKT-KKEYAVKIIAKNNVS-NGEIDR------------LRKEAKILSQLD---HKNIVKFERVFESETR------IFIVM
.  .| || |.||||  |. |.| ....|.||| |.  . .  ...            .|.|..|...|.   |.||.|.  |.| ..       |..||
YRIGKTLGKGSFGKVKLATHIRTTGEKVAIKIIDKKKIWNDPWMKKNKCGQKHESDMRIRREIQIMKMLNIGKHPNIIKLYEVIETPEHDIETKKIYLVM

ELLLGGT--LRQLMSERKKSKQWFTEQEAAQIMNNIINGVAYFHGKSIVHRDLKPDNILIGDKNDLDTVKIADFGLSAAFE---AKKSISFTQQCGTLIY
|.  ||   | .   .... .. ..| || ..   |. .|.| | . |||||.||.|||. ....  ..||.|||.|. ..    ..   .. .||.. |
EYCSGGEMDLFDYIVKHGHRRGRMPEHEARRYFRQIVSAVNYCHSHGIVHRDIKPENILLDENGNN-NIKIIDFGFSNMYRPCIFGPGQKLKTFCGSPPY

MAPEFFIQ--KTY
|||| |    | |
MAPEIFQGNNKPY
Kinase 20983.AA Pkinase 92-291 35 1.1e-56 199.42 Pfam 1-194 (293) Show / Hide 
Range on Protein: 92-291
Range on HMM: 1-194/293
Sequence Identity: 35% (74 aa)

FLPIKILGSGAFGKVVQAREIKTKKEYAVKIIAKNNVSNGEIDRLRK--EAKILSQLDHKNIVKFERVFESETRIFIVMELLLGG----TLRQLMSERKK
.  ....|||.||.| ......| |..||||| | . . ..  ..|.  |..|.  |.|.|||.. ..||....| .|||.. ||     |  ..|   .
YHIGRKIGSGSFGCVYKCHHKGTGKIVAVKIIKKRHEKSWKDQTHRRLSEIQIMKRLNHPNIVRLYDWFEDKDHIYMVMEYCEGGLYVMDLFDYIST--W

SKQWF--TEQEAAQIMNNIINGVAYFHGKSIVHRDLKPDNILIGDKNDL-DTVKIADFGLSAAF-EAKKSISFTQQCGTLIYMAPEFFIQKTYSKLLCHG
.. .|  .|.|.  .|  |. |..| | ..|.||||||.|||| ..... ..|||.||||.. | . ..|  .|  |||. |||||  |.          
RHGCFYFSEWECKFYMYQILRGLEYCHSMGIIHRDLKPENILIDNNGHIDACVKICDFGLAKQFDY-NNS--MTTFCGTPWYMAPEV-IR----------

THPLYDPLVD
... |.| ||
GGQYYGPKVD
Kinase 20983.AA Ciliate-E2-Unclassified 92-343 25 1.4e-56 194.31 In-house 1-352 (352) Show / Hide 
Range on Protein: 92-343
Range on HMM: 1-352/352
Sequence Identity: 25% (91 aa)

FLPIKILGSGAFGKVVQAREIKTKKEY-------AVKIIAKNNVSNG--------EIDRLR--------KEAK-ILSQLDHKNIVKFERVFESETRIFIV
.  ||..|.|.|||| .....|.| .|        ..|...... |         |. ..         |... ||....| .|||.. .|...  |.||
YKIIKQIGQGGFGKVYKCQHKKQK-QYYAMKYMKKIQIYKQKQIMNKDEIMNEMKEMNNKKKYHQRKYNKIMQQILLNHPHPFIVKMFYCFQDKQNIYIV

MELLLGGTLRQLMSERKK-------------SKQWFTEQEAA-----QIMNNIINGVAYFHGKS-IVHRDLKPDNILIGDKNDLDTVKIADFGLSAAFEA
||.. ||.|.| ...|||             ... ||||.|.     ...  |..|  | | |  |.|||.||.|||. ...    .||.|||.|   . 
MEYCEGGDLWQYIKKRKKQKQKGNDLFHNMKQRKIFTEQQAKYKKAKFYFAQILQGLEYLHHKNNIIHRDIKPENILFDNNGKNYYIKIIDFGISKKYQQ

K--------------KSISFTQQCGTLIYM----APEFFIQKTYSKL----------------LCHGTHPLYDPLVDDNK--------------SFKNKI
               |.  ....|||..||    ||| . .. |..                 .. |..| ||.  ....               ..|..
NNNCDTNQQQKMQIWKQQMMWTFCGTPNYMPQYTAPEVLQGQNYDHSKAYKCDIWSLGVILYEMLFGYYPFYDNNCEQHQQLITQWINNAYRKQLYQNIK

QKNPQIQ------FPSCFSDITKNLIQ----KMTLIDPSARYTANQVIYHPWI
|||.|..      .|   |.  |..|.    ||   .|. |.|..|.. |||.
QKNIQFPKFPWQQIPKHWSPEAKDFINDLLQKMLKKNPNKRITFEQILNHPWF
Kinase 20983.AA ULK 92-343 27 2e-55 190.46 In-house 1-324 (324) Show / Hide 
Range on Protein: 92-343
Range on HMM: 1-324/324
Sequence Identity: 27% (90 aa)

FLPIKILGSGAFG-KVVQAREIKT---KKEYAVKIIAKNNVSNGEID--------RLRKEAKILSQLD---HKN--IVKFERVFESETR--IFIVMELLL
.  ...||.|.|| || ..| .||   .. .|.|.| |.. .. . .         |..| .|. .|.   |.|  |||.  .||. .   |.|.||.  
YCLNHCLGKGSFGVKVYKGRNKKTNTQNQYVACKMIDKKKMNKKKNEQEGQYMWQLLKNEIQIMKKLKELKHPNHHIVKLYDWFETSNHNNIYIIMEYCN

GGTLRQLMSERKK-----SKQWFTEQEAAQIMNNIINGVAYFHGKSIVHRDLKPDNILIGDKNDLD---------TVKIADFGLSAAFEA--KKSISFTQ
||.|.|.. ..||      |. ..|||| |..  |.||  . | . |.|||.||.|||| ...            ..||||||..  ..   .    ...
GGDLEQYIKKNKKLPETEEKKRLSEQEAIQFFKQICNGFKELHKHNIIHRDIKPQNILIHNGQPKTDSKKVHPNGVLKIADFGFAKHVDNNNMEQQMCQT

QC------GTLIYMAPEFFI----QKTYS-K------------LLCHGTHP----LYDPLVDDNKSFKNK------IQKNPQIQFP-----SCFSDITKN
..      || .||||. .     || |. .             .  |  |     .|     ... .|.      . || .||||       .|. .|.
CVNEKRIKGTPLYMAPQILQGQGEQKPYYDYKCDIWSLGCIFYEMLYGKYPFFSWFNDQYLY-IQKLINNGKEQQIYIKNQPIQFPKPPKDPKISPECKD

LIQKMTLIDPSARYTANQVIYHPWI
||..|  .|.. | .  ... |||.
LIRRMLQYDEKDRISWEEIFNHPWF
Kinase 20983.AA CDPK 92-267 39 3e-55 167.99 In-house 1-184 (271) Show / Hide 
Range on Protein: 92-267
Range on HMM: 1-184/271
Sequence Identity: 39% (74 aa)

FLPIKILGSGAFGKVVQAREI-KTKKEY-AVKIIAKNNVSNGE-IDRLRKEAKILSQLDHKNIVKFERVFESETRIFIVME--LLLGGTLRQLMSERKKS
.   |.||.|.|| |  . .  ||. |  |.|||.|..|.. | .... .| .||.|||| ||.|.  ... |  ..||||  .. || | .   |... 
YKIKKVLGKGHFGQVRKVKHKQKTNQERVAMKIIPKSRVKDKEQQQQFFNEIEILKQLDHPNIIKIYEFYQDEKNYYIVMETEYCTGGELFDYIIEKGH-

KQWFTEQEAAQIMNNIINGVAYFHGKSIVHRDLKPDNILIGDKNDLD----TVKIADFGLSAAFEAK---KSISFTQQCGTLIYMAPE
   |||.|||.||. |.. |.| | . |||||||| |||   |.| .    ..|. |.|.|  |. .    .  ..|.|||  |.|||
---FTEKEAAYIMRQILSAVNYCHSNNIVHRDLKPENILFDSKKDDSWVIYNIKVIDWGTSKKFDQNQKIEDKKMSQRCGTPYYIAPE
Kinase 20983.AA CAMK-Unique 95-267 25 1.9e-53 174.68 In-house 4-245 (363) Show / Hide 
Range on Protein: 95-267
Range on HMM: 4-245/363
Sequence Identity: 25% (61 aa)

IKILGSGAFGKVVQAREIKTKKEYAVKIIAKNNVSNGEIDR------------------LRKEAKILSQLDHKNIVKFERV----FESET----------
..|.|.|.||.|  .  ..|.|..|.|.. |  ..|   .                   |..|. |.  .|| ||.|.. .    |. ..          
HRIIGHGNFGHVYECMDRETGKKWACKMVKKQTHGNKKQKQQRNFDLRYKITEKRRDMKLKREHQIWKMVDHPNIIKLYDWNNPIFCDRKYPLCDLIIKT

-----RIFIVMELLLGGTLRQLMSER----------------KKSKQWFTE--QEAAQIMNNIINGVAYFHGKSIVHRDLKPDNILIGDK-ND-------
     ...||||.. ||.| ... ..                |.... |.|   ....||  .   ||| | ..|||||||..||..    .|       
PRALPYMYIVMEYCQGGDLFDWIQKWDEFYFNFIIKFDFNILKRCQGHFSERCWDTCFIMQCLLSAVAYMHSQDIVHRDLKLENIMVCYSFKDNNHHRDF

-----LDTVKIADFGLSAAFEAKKSIS-FTQQCGTLIYMAPE
        .|..||||.. .. .|. .     |||..|||||
PYDWSNWHIKLCDFGLCCHYNHNKMCHMMQTMCGTPCYMAPE
Kinase 20983.AA Pkinase_Tyr 92-243 33 4.3e-25 85.6 Pfam 1-158 (270) Show / Hide 
Range on Protein: 92-243
Range on HMM: 1-158/270
Sequence Identity: 33% (54 aa)

FLPIKILGSGAFGKVVQAREI----KTKKEYAVKIIAKNNVSNGE--IDRLRKEAKILSQL-DHKNIVKFERVFE--SET-RIFIVMELLLGGTLRQLMS
   .| ||.||||.|....      .|| . |||.. |.. .  .  .. . .||||..|| .|.|||..  |    .|  .|.||||.  .| |.    
ITFGKKLGEGAFGEVYKGTWKGDPDNTKIPVAVKML-KEGAMHEQNCREDFMREAKIMKQLGHHPNIVRLYGVCTDQGEPNQIYIVMEYMPHGDLLDYLR

ERKKSKQWFTEQEAAQIMNNIINGVAYFHGKSIVHRDLKPDNILIGDKNDLDTVKIADFGLS
... .|| .| ..  |.   | .| .| . | ..||||   |.|...  .. .|||.||||.
KHREDKQPLTMKDLLQMCWQIAKGMEYLESKNCIHRDLAARNCLVTE--NN-VVKICDFGLA
Kinase 20983.AA TyrKc 92-347 20 3.9e-16 38.13 SMART 1-280 (280) Show / Hide 
Range on Protein: 92-347
Range on HMM: 1-280/280
Sequence Identity: 20% (62 aa)

FLPIKILGSGAFGKVVQAREIKTKKEYAVKIIAKNNVSNGEIDRLRKEAKILSQL--DHKNIVKFERVFESE-------TRIFIVMELLLGGTLRQLMSE
   .|.||.||||.|.... .    . ||| . ..      .  ...||.|...|  .|.|||..  |  ..         ..||||.  .| |..   .
ITLGKKLGEGAFGEVYKGTWK---IQVAVKMLKEDA-----REDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPHGDLKDYLRK

RKKSKQWFTEQEAAQIMNNIINGVAYFHGKSIVHRDLKPDNILIGDKNDLDTVKIADFGLSAAFEAK-------KSISFTQ-QCGT--LIY--MAPEFFI
...    .. ..  ...  | .| .| | | ..||||   |.|.|...   ||||.||||| . . .       . .. .. ..|   | .  |||| . 
HRPK---LCMKDLLSFCWQIACGMEYLHSKNCIHRDLAARNCLVGENH---TVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGKTMLPIRWMAPECIN

QKTYSKL------------LCHGTHPLYDPLV---DDNKSFKNKIQKN-PQIQFPS--------CFSDITKNLIQKMTLIDPSARYTANQVIYHPWITQK
 ....              ..    . |   .    .|.   .....     | |.        | ... . ....    ||. | | ...       ..
YGKFTTKSDVWSFGVCMWEIFTYGQQPYPGMIQQMMSNQEVIEYVKQGYRMPQPPNDYPMSFVCCPDEMYQ-IMKQCWHEDPEDRPTFSEI------HEC

L
.
F
Kinase 20983.AA CAMK1 317-343 48 8.6e-11 27.54 In-house 250-276 (276) Show / Hide 
Range on Protein: 317-343
Range on HMM: 250-276/276
Sequence Identity: 48% (13 aa)

KNLIQKMTLIDPSARYTANQVIYHPWI
|..| .|   ||. |||. |.. ||||
KDFIKHMLEVDPKKRYTCEQCLNHPWI
Kinase 20983.AA CAMK 312-343 43 3.3e-09 25.08 In-house 394-425 (425) Show / Hide 
Range on Protein: 312-343
Range on HMM: 394-425/425
Sequence Identity: 43% (14 aa)

FSDITKNLIQKMTLIDPSARYTANQVIYHPWI
.|.  |.||.||   ||. |.|. |.  |||.
VSQECKDLIRKMLQVDPEKRMTIEQCLNHPWM
Kinase 20983.AA CDPK 317-343 48 6.7e-09 23.66 In-house 245-271 (271) Show / Hide 
Range on Protein: 317-343
Range on HMM: 245-271/271
Sequence Identity: 48% (13 aa)

KNLIQKMTLIDPSARYTANQVIYHPWI
|.||.||   ||  |..|.|.  |||.
KDLIRKMLCYDPKKRMSAQQALQHPWF
Kinase 20983.AA Ciliate-E2a 310-343 41 1e-08 21.79 In-house 242-275 (275) Show / Hide 
Range on Protein: 310-343
Range on HMM: 242-275/275
Sequence Identity: 41% (14 aa)

SCFSDITKNLIQKMTLIDPSARYTANQVIYHPWI
...|. .|.|..||   ||. |.||.|   ||| 
EKCSKECKDLMKKMLEKDPKKRITAQQALNHPWF
Kinase 20983.AA CAMKL 289-343 25 2e-06 16.31 In-house 244-297 (297) Show / Hide 
Range on Protein: 289-343
Range on HMM: 244-297/297
Sequence Identity: 25% (14 aa)

LVDDNKSFKNKIQKNPQIQFPSCFSD-ITKNLIQKMTLIDPSARYTANQVIYHPWI
. .||.  . ....    ..|  ..    ..||.||   .|. |.|. |.  ||| 
QGKDNI-YLYWKIMCG-YYPPIWYHVSDCRDLIRKMLQVNPEKRPTIHQIMNHPWM
Kinase 20983.AA CAMK-Unique 313-343 29 9e-06 14.81 In-house 333-363 (363) Show / Hide 
Range on Protein: 313-343
Range on HMM: 333-363/363
Sequence Identity: 29% (9 aa)

SDITKNLIQKMTLIDPSARYTANQVIYHPWI
|.  |.....   .||. | .|.. . |.||
SQEAKDFVKCCMTVDPDHRWSAKELLEHQWI
Kinase 20983.AA Pkinase 327-343 52 0.014419 10.16 Pfam 277-293 (293) Show / Hide 
Range on Protein: 327-343
Range on HMM: 277-293/293
Sequence Identity: 52% (9 aa)

DPSARYTANQVIYHPWI
||. |.|| |.  |||.
DPKKRPTAEQILQHPWF