8815

Species: Tetrahymena
Alias: 555, PreTt08815, TTHERM_00191650, 15.m00526, 8815, 3697.m00237
External Links: Tetrahymena Genome Database (TGD)
Annotation:

Classification

Group: Other
Family: Ciliate-B3

Sequence

Name Sequence Type Origin Length Description Download
8815.AA Protein None 464 None Fasta, JSON
8815.kin_dom Protein Kinase Domain None 38 None Fasta, JSON
8815.NA RNA None 1395 None Fasta, JSON

Protein domain

Protein domains of 8815.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Kinase 8815.AA Ciliate-B3 105-172 72 4.6e-37 128.49 In-house 1-69 (69) Show / Hide
Range on Protein: 105-172
Range on HMM: 1-69/69
Sequence Identity: 72% (51 aa)

LALKLFHLVVEKIKILHSKNICHCDIKVHNILLVNVQDKENYKVIIIDFGQYQ--ELNRKSTMNCGTTEF
.|||.||.|||||||||.||||||||||.||| ||.||||||||||||||..|  . | ||.| |||  .
FALKHFHQVVEKIKILHEKNICHCDIKVDNIL-VNQQDKENYKVIIIDFGHCQRKCQNCKSEMICGTLTY

Kinase 8815.AA MLCK 120-175 30 6.3e-13 29.88 In-house 113-168 (257) Show / Hide
Range on Protein: 120-175
Range on HMM: 113-168/257
Sequence Identity: 30% (18 aa)

LHSKNICHCDIKVHNILLVNVQDKENYKVIIIDFGQYQELNRK---STMNCGTTEFNPP
.|..||.| |.| .||....   ..  .. |||||. ......    . ..|| ||..|
MHWQNIVHLDLKPENIMCQT---RTSHQIKIIDFGLARKYDPDEKKVKVMFGTPEFVAP

Kinase 8815.AA Ciliate-E2 117-213 24 7.4e-13 40.46 In-house 173-291 (365) Show / Hide
Range on Protein: 117-213
Range on HMM: 173-291/365
Sequence Identity: 24% (32 aa)

IKILHSKN-ICHCDIKVHNILLVNVQDKENYKVIIIDFG---QYQELNRKSTM-------------------------------NCGTTEFNPPKLIEDA
.. ||||| |.| |||  |||.          . |||||   .|.. | . |.                                ||| .. .|  ..  
LEYLHSKNNIIHRDIKPENILF----------IKIIDFGLSKKYDDDNQNRTHKQQCKWYMFKNDTSRTPGYMDQIIQQNMFNTICGTPGYMAPEILNGK

DRLKKFGKQIEEYSPQELDVYQLGMLLFRMLT
.  .    | ...   . |.. ||..|..||.
KYDNQ---QKQKGYDYKCDIWSLGVILYEMLF

Kinase 8815.AA CAMK 120-175 24 2.8e-12 35.13 In-house 195-289 (425) Show / Hide
Range on Protein: 120-175
Range on HMM: 195-289/425
Sequence Identity: 24% (23 aa)

LHSKNICHCDIKVHNILLVNVQDKEN------------YKVIIIDFGQYQELNR--------------------------KSTMNCGTTEFNP-P
.||.||.|.|.|  ||||..  | ..            ... |||||  .....                          | .  ||| |. . |
CHSHNIVHRDLKPENILLDDNNDDSDPVEHDEIFDWNNNNIKIIDFGFANKFDPGENNFMCSDYKGGEMHNQWTTPTEGQKMKTFCGTPEYMAAP

Kinase 8815.AA MSK 117-213 27 4.3e-10 30.29 In-house 114-205 (277) Show / Hide
Range on Protein: 117-213
Range on HMM: 114-205/277
Sequence Identity: 27% (28 aa)

IKILHSKNICHCDIKVHNILLVNVQDKENYKVIIIDFGQYQELNRK---STMN-CGTTEFNPPKLIEDADRLKKFGKQIEEYSPQELDVYQLGMLLFRML
.. .|.| | | |.|  |||. . .|  | .| .||||   ....     .   |.| .. .| ......      .| ..|...  |.. || .|. ||
VDHMHQKGIIHRDLKPENILFDDEED--NGHVKLIDFGFARLFPQDEEWRMKSPCFTLHYMAPEMLRRGY------AQDGGYDEA-CDWWSLGVILYTML

T
|
T

S_TKc 8815.AA S_TKc 9-370 10 1.6e-09 -37.47 SMART 1-231 (231) Show / Hide
Range on Protein: 9-370
Range on HMM: 1-231/231
Sequence Identity: 10% (42 aa)

YQLNDVKFEGGQSTGLIYTDQKTKQVYFKKIFDEEIDYVREKAFYKEILIKIDPKDRSSFLELLHFNDNNKE--LIFPFINS---KLVDKCTKQKGI---
|.. ..  .|. ..    .. ||....  || .        . ...|| |     .      |. . .. ..  ... ...     | |   |...    
YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK--------EHIRREIQILKK--HHPNIVKLYDVFQD-DHLYMVMEYCDGDLGDLFDYIKKRGRHGLR

--KSRYLALKLFHLVVEKIKILHSKNICHCDIKVHNILLVNVQDKENYKVIIIDFGQYQELNRKSTMNCGTTEFNPPKLIEDADRLKKFGKQIEEYSPQE
   .   | .... ... .. .||..|.|.|.|  |||| .        . |.|||   .|    |  ||| .. .| ..               |.. .
FPFPE-HARFYMYQICCALEYCHSHGIIHRDLKPENILLDE-------HIKICDFGLARQL----TTFCGTPWYMAPEVL--------------GYGKCK

LDVYQLGMLLFRMLT--QLYLSISLKKVAQNKMKKDFFKEQIKKLYKSEYKTELILDDDIFDLGKIKPDEEDLQFEDMVKFKEDQNSSRSKGESIQNEIK
 |.. .| .|. ||.   ..    .... .. .                                                                   
CDWWSCGCILYEMLCGYPPFP--QMQMMFKKIG-------------------------------------------------------------------

QAHKKYCDLMRESENFDQFNEWQGAFFKLQPRKIDRKKLYGGSLLTEMSTEDLLNVLLSILAENNN-----QIFS-------QNIF
                                                 ...... .  .|  . .     ...           |
-------------------------------------------------SPEAKDFIRKCLQKDPEKRPTAEALQDEWDIKCHPWF

Kinase 8815.AA Ciliate-E2-Unclassified 117-216 25 2.6e-09 28.47 In-house 156-268 (352) Show / Hide
Range on Protein: 117-216
Range on HMM: 156-268/352
Sequence Identity: 25% (32 aa)

IKILHSKN-ICHCDIKVHNILLVNVQDKENYKVIIIDFGQYQELN------------------RKSTMNCGTTEFN----PPKLIED-ADRLKKFGKQIE
.. ||.|| |.| |||  |||. | .   ||.. |||||   ...                   ... .||| ..     .| ...      .|.     
LEYLHHKNNIIHRDIKPENILFDNNGK--NYYIKIIDFGISKKYQQNNNCDTNQQQKMQIWKQQMMWTFCGTPNYMPQYTAPEVLQGQNYDHSKA-----

EYSPQELDVYQLGMLLFRMLTQLY
     . |.. ||..|. ||.. |
----YKCDIWSLGVILYEMLFGYY

Kinase 8815.AA C8 113-208 23 2.1e-08 25.43 In-house 132-226 (226) Show / Hide
Range on Protein: 113-208
Range on HMM: 132-226/226
Sequence Identity: 23% (24 aa)

VVEKIKILHSKNICHCDIKVHNILLVNVQDKENYKVIIIDFGQYQELNRKS----TMN---CGTTEFNPPKLIED-ADRLKKFGKQIEEYSPQELDVYQL
... .  .|.||| | ||| ||.| |  . ...... . |||    .        . .   ||| ..  |  ...  ...|.. .|         |....
MIDGVNYIHCKNIMHRDIKPHNFL-VCLDQNYGFEIKLCDFGFASQVSKNKSHIQSKKMNTCGTWAYFAPEIEKKQDNQYKQYRIQ--------SDLFSV

GMLL
|..|
GLVL

Kinase 8815.AA Ciliate-E8 117-156 45 2.7e-08 22.03 In-house 102-138 (138) Show / Hide
Range on Protein: 117-156
Range on HMM: 102-138/138
Sequence Identity: 45% (18 aa)

IKILHSKNICHCDIKVHNILLVNVQDKENYKVIIIDFGQY
. .||. || |||.|  |||..   |    |. |||||  
FCYLHNNNIIHCDFKLNNILVQRNDD---TKIKIIDFGFS

Kinase 8815.AA CMGC 117-154 27 3.9e-07 18.49 In-house 195-249 (513) Show / Hide
Range on Protein: 117-154
Range on HMM: 195-249/513
Sequence Identity: 27% (15 aa)

IKILHSKN--ICHCDIKVHNILLVNVQDK---------------ENYKVIIIDFG
.| .||..  |.|.|.|  |||. .  .                .|... |.|||
LKYCHSHWGNIIHRDLKPENILINHNCELITRMMWKSEDWNPCQKNGRLKICDFG

Kinase 8815.AA DAPK 120-154 48 4.3e-07 16.4 In-house 119-152 (264) Show / Hide
Range on Protein: 120-154
Range on HMM: 119-152/264
Sequence Identity: 48% (17 aa)

LHSKNICHCDIKVHNILLVNVQDKENYKVIIIDFG
.|||.||| |.|  || | .     | .. |||||
MHSKHICHFDLKPENIMLLD-RNVPNPRIKIIDFG

Kinase 8815.AA Pkinase 120-213 28 2e-06 23.75 Pfam 124-207 (293) Show / Hide
Range on Protein: 120-213
Range on HMM: 124-207/293
Sequence Identity: 28% (28 aa)

LHSKNICHCDIKVHNILLV-NVQDKENYKVIIIDFGQ---Y-QELNRKSTMNCGTTEFNPPKLIEDADRLKKFGKQIEEYSPQELDVYQLGMLLFRMLT
.||..|.|.|.|  |||.. | . ..  .| |.|||    .    |.  |  ||| .. .| .|              .| ... |.. .| .|. ||.
CHSMGIIHRDLKPENILIDNNGHIDA--CVKICDFGLAKQFDY-NNS-MTTFCGTPWYMAPEVIR-----------GGQYYGPKVDMWSCGCILYEMLC