Gene 17861 (Tetrahymena)

17861

Species: Tetrahymena
Alias: TTHERM_01082870, PreTt17861, 17861, 806, 224.m00031
External Links: Tetrahymena Genome Database (TGD)
Annotation:

Classification

Group: Other
Family: Ciliate-D1

Sequence

Name Sequence Type Origin Length Description Download
17861.AA Protein None 603 None Fasta, JSON
17861.kin_dom Protein Kinase Domain None 272 None Fasta, JSON
17861.NA RNA None 1812 None Fasta, JSON

Protein domain

Protein domains of 17861.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Kinase 17861.AA TKL 306-566 18 2.6e-41 143.57 In-house 1-364 (364) Show / Hide 
Range on Protein: 306-566
Range on HMM: 1-364/364
Sequence Identity: 18% (69 aa)

LGFGVQASVHKATYKG----------RPVAVKVYSLEK-------------------------EKSQKIKCFLRELRALILSRHPNVVHLYGVGQYKHL-
.| |  . |.|....|          ..||||... .                          | |.  ... .|.. ..  ||||.|...|. ..    
IGSGGFGEVYKGKWRGWGGKCPSDTGKDVAVKKFKSHNDDEFTKNSQENNDNNNYSDMQLNDPEASWFRFFEEEEIMMMSRLRHPNIVQFMGYCCCPPCG

------------FYLVLELTSNQNVLDFICRNRKNWDQKPFNNEFIRALSELSLG---LHQMSV-----SGILHRDIQTKNILISHSDQ--NFDYQNLTQ
            ...| |. .. . |...             . ..|   . ..|   ||.|        .|.|||. .||||.    .  . .|     
CVCMHPVGPWGQLCIVMEYCPGGSLLHYLH-----------WHQRCRWALDIARGMNYLHSMNPKWCTKPPIIHRDLKSKNILVDENWTNVS-NYM--YN

LDKNCTLKICDFGLSA-IEEDKD---------------------SIVRGSTRHYSPESMEDK---------------RNYYPQSDVYMLGNSIWEMVYTK
  .....||||||||  ......                     . ..|..|. .|| ....               . | ...|||  |  .||..  .
PNADWCCKICDFGLSRFMSQSGNMNDTMTTMMESAEHQNNRKTTMTQCGTPRWMAPEVLRGQMNYTEKVGIDEFCKGFEYSEKCDVYSFGIVLWEILTRC

IIFT-HSNVGEV---------HKTVISGEREEFD------------DKCPPEIQSVIEKCWKHNYLERPSFLEISNDL
. .  . .  ..          . .  |.| . .            . |||.. . ...||.|.  .||||.||   |
RPYYDYPYMPMIFQDPFEEMFMMVCDKGLRPPIPPIWQNHHKMCPCPDCPPSMKKLMQDCWDHDPEKRPSFQEILKRL
Kinase 17861.AA TKL-Unique 302-566 24 2.9e-30 104.02 In-house 1-290 (290) Show / Hide 
Range on Protein: 302-566
Range on HMM: 1-290/290
Sequence Identity: 24% (74 aa)

FTQQLGFGVQASVHKATYKGRPVAVKVYS-LEKEKSQKIKCFLRELRALILSR-HPNVVHLYGVGQ----YKHLFYLVLELTSNQNVLDFICR----NRK
|   .| |....| |....| |||.|. . .|.  ..... | .|.. .   . |||.||..|.      |   ...|.|  .  .  | . .    |  
FWNKIGEGGYGQVYKGKWRGYPVAIKQFHPNEDSSNEMMQEFENEVNWMKKLHYHPNIVHYMGYCMDHQVYPPNMCIVMEYCPGGSLYDVLHQNNNNNNN

NWDQKPFNNE-FIRALSELSLGLHQMSVSG--ILHRDIQTKNILISHSDQNFDYQNLTQLDKNCTLKICDFGLSAIEE-DKDSIVR-----------GST
| . ...|.. ...     ..|..  . ..  |.|||. ..|.|..        .|..    |   |||||||| .   . .....           ||.
NNNNCKLNMQQRVKMAIDIAQGMYYLHHCEPPIIHRDLKSSNFLVD--------NNSNIAEWN--IKICDFGLSKFNSKINKMTNNEHKGTRNQTRCGSF

RHYSPESMEDK-RNYYPQSDVYMLGNSIWEMVYTKI---------IFTHSNVGEVHKTVISGEREEFDDKCPPEIQSVIEKCWKHNYLERPSFLEISNDL
|  .|| ...    |  .||||  |   ||.. .||          ...  . |. ...  . |..  . ||.|..  |..||.|.  .|||| || . |
RWMAPEVLRMNFCQYSEKSDVYSFGIVLWEIATRKITKTYKKPYQGMDQEQWCEMVHYMEENYRPPIPNHCPKEYRDLIQQCWHHDPSQRPSFDEIIHRL
Kinase 17861.AA TK 300-566 14 3.9e-29 94.2 In-house 1-486 (486) Show / Hide 
Range on Protein: 300-566
Range on HMM: 1-486/486
Sequence Identity: 14% (73 aa)

LDFTQQLGFGVQA---SVHKATYKGR---------------------------PVAVKVYSLEKEKSQK-IKC-----------FLRELRALILSR----
. . ..|| |       |.|....||                           |||||.  .. . ||.  .            ||.|.... . .    
ITLGKKLGEGQFGSFGEVYKGEWRGRNPWNGKRFPCHMTVTLKCKNGKEGGKTPVAVKMLKEGDAMSQEEFFDEEMHDRDGGEDFLEEAEEMKMMCHSLG

-HPNVVHLYGVGQYK------------HLFYLVLELTSNQN----VLDFICRNRKNWDQKPFNNE-----------------------------------
 |||.|.||||   .            . ...|.|. .. .     .|.  ..|..  . . ...                                   
HHPNIVRLYGVCTQGEPKPCFEVVVHQEPWMIVMEYMPHGDMDGSLRDYLRKCRPKFQHEQDCPDNQHNKYPPSKLHHCMKGDITYSHESNSPCPEEQDY

------------------------------FIRALSELSLG---------LHQMSVS---GILHRDIQTKNILISHSDQN---FDYQNLTQLDKNCTLKI
                              ..     |            ||.. ..   .. |||. . |.|.......   |        .  .. ||
DDDLIKDHPPPLTTKDLLQMAWQWCLTCKHQLTMHQLL-MCWQIACGMEYLHSKNCEFIQNFVHRDLAARNCLVGENNVCKWHF-------DGCGPVCKI

CDFGLS---------AIEEDKDSIVRGSTRH----------------------------YSPESMED--------KRNYYPQSDVYMLGNSIWEMVY--T
.|||||         .|..|.|  ...| ..                            ..||...|        .. . ..|||...|  .||..    
ADFGLSRQGSGVLARDIYSDDDYYRKSSYGTGRPMWPFEDDPWQDYYRQQSGGKLPIRWMAPECLNDRVFSEAEKYGKFTTKSDVWSFGVLMWEIFTYGQ

KIIFT-HSN--------VGEVHKTVISGERE--------------EFDDKCP--------------PEIQSVIEKCWKHNYLERPSFLEISNDL
.     .||        . || . . .| |.              .  . ||              .|.. .. .||...  .||.| .. . |
EPYYGGMSNQDVWKDGDNQEVMEYLRRGGRLCRSGLNEVGYRMRMPQPPHCPDWMRYRMHPPHCPPEEYYDLMQQCWHYDPEDRPTFSQLHEQL
Pkinase 17861.AA Pkinase 300-566 21 7.6e-29 103.08 Pfam 1-293 (293) Show / Hide 
Range on Protein: 300-566
Range on HMM: 1-293/293
Sequence Identity: 21% (68 aa)

LDFTQQLGFGVQASVHKATYKGRP--VAVKVYSLEKEKSQKIKCFLR--ELRALILSRHPNVVHLYGVGQYKHLFYLVLELTSNQ----NVLDFICRNRK
. . ...| |  ..| |.. || .  ||||. ....|||.| .  .|  |.. .   .|||.| ||.. ..|   |.|.|.  .        |.| .   
YHIGRKIGSGSFGCVYKCHHKGTGKIVAVKIIKKRHEKSWKDQTHRRLSEIQIMKRLNHPNIVRLYDWFEDKDHIYMVMEYCEGGLYVMDLFDYIST---

NWDQKPF---NNEFIRALSELSLG---LHQMSVSGILHRDIQTKNILISHSDQNFDYQNLTQLDKNCTLKICDFGLSA---IEEDKDSIVRGSTRHY-SP
 |....|    .| .. . ..  |   .|.|   ||.|||.   ||||.. ... .           ..|||||||..   .  .    ..  |..| .|
-WRHGCFYFSEWECKFYMYQILRGLEYCHSM---GIIHRDLKPENILIDNNGHIDA-----------CVKICDFGLAKQFDY-NNS-MTTFCGTPWYMAP

ESMEDKRNYYPQSDVYMLGNSIWEMVYTKIIFTHS------NVGEVHKTVISGEREEFDD-KCP-------------------PEIQSVIEKCWKHNYLE
|   . . | | .|.. .|  ..||.  . .| ..      .  .... . ... ..  . .|.                   .| ...|..|.. .  .
EVIRGGQYYGPKVDMWSCGCILYEMLCGRPPFPGHCWHDNHDQMQMICRIMGPPLHFDWPWWCSISYFFFRHWHFHWTFHNWSEECKDFIKWCLCKDPKK

RPSFLEISND--L
||.. .| ..  .
RPTAEQILQHPWF
Kinase 17861.AA S_TKc 300-571 21 4.4e-25 90.58 SMART 1-231 (231) Show / Hide 
Range on Protein: 300-571
Range on HMM: 1-231/231
Sequence Identity: 21% (62 aa)

LDFTQQLGFGVQASVHKATYKG--RPVAVKVYSLEKEKSQKIKCFLRELRALILSRHPNVVHLYGVGQYKHLFYLVLELTSN--QNVLDFICRNRKNWDQ
 .. ...| |  ..|.|.. |.  | ||.|. .         . ..||.. |   .|||.|.||.| |  . .|.|.|. ..   ...|.|......  .
YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK---------EHIRREIQILKK-HHPNIVKLYDVFQD-DHLYMVMEYCDGDLGDLFDYIKKRGRHGLR

KPFNNEFIRA-LSELSLGLHQMSVSGILHRDIQTKNILISHSDQNFDYQNLTQLDKNCTLKICDFGLSAIEEDKDSIVRGSTRHYSPESMEDKRNYYP-Q
.||.   .|  . .. ..|  .   ||.|||.   |||...                 ..|||||||...     . . |.    .|| .     | .  
FPFPE-HARFYMYQICCALEYCHSHGIIHRDLKPENILLDE-----------------HIKICDFGLARQL----TTFCGTPWYMAPEVL----GYGKCK

SDVYMLGNSIWEMVYTKIIFTHSNVGEVHKTVISGEREEFDDKCPPEIQSVIEKCWKHNYLERPSFLEISN----DLKQIYM
.|.. .|  ..||.. .  |   .. .. | .            .||  . |.||.. .  .||.  |. .      .  ..
CDWWSCGCILYEMLCGYPPFP--QMQMMFKKIG-----------SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF
Kinase 17861.AA TyrKc 300-566 22 5.8e-24 86.84 SMART 1-280 (280) Show / Hide 
Range on Protein: 300-566
Range on HMM: 1-280/280
Sequence Identity: 22% (69 aa)

LDFTQQLGFGVQASVHKATYKGRPVAVKVYSLEKEKSQKIKCFLRELRALILS--RHPNVVHLYGVGQYK-------HLFYLVLELTSNQNVLDFICRNR
. . ..|| |    |.|.|.| ..||||.   ..     .. |.||.| .     .|||.| ||||   .       .  ..|.|. .. . .|.. ..|
ITLGKKLGEGAFGEVYKGTWK-IQVAVKMLKEDA-----REDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPHGDLKDYLRKHR

KNWDQKPFNNEFIRALSELSLGLHQMSVSGILHRDIQTKNILISHSDQNFDYQNLTQLDKNCTLKICDFGLSAIEEDK-------DSIVR----GST---
..      . ...      . |    .  .. |||. . |.|...                 | ||.|||||   .|.       | ..     |.    
PK----LCMKDLLSFCWQIACGMEYLHSKNCIHRDLAARNCLVGENH---------------TVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGKTML

--RHYSPESMEDKRNYYPQSDVYMLGNSIWEMV-YTKIIFTH-----SNVGEVHKTVISGEREEFDDK--------CPPEIQSVIEKCWKHNYLERPSFL
  | ..||.. ... . ..|||.. |  .||.  | .           .  ||.. | .|.| .  .         ||.|. .....||...  .||.| 
PIRWMAPECI-NYGKFTTKSDVWSFGVCMWEIFTYGQQPYPGMIQQMMSNQEVIEYVKQGYRMPQPPNDYPMSFVCCPDEMYQIMKQCWHEDPEDRPTFS

EISNDL
||  ..
EIHECF
Kinase 17861.AA Ciliate-E2 300-462 20 5.4e-22 72.27 In-house 1-203 (365) Show / Hide 
Range on Protein: 300-462
Range on HMM: 1-203/365
Sequence Identity: 20% (45 aa)

LDFTQQLGFGVQASVHKA-TYKGRP-------------------VAVKVYSLEKEKSQKIKCFLRELRALI----------------LSRHPNVVHLYGV
 .| ...|.| ..|| |.  .| .                    |..| | ..  | ..|. ...|.. .                 .  |||.. .| .
YKFIKKIGQGNFGSVYKCKVWKVQKQFAIKIIDQKQQRQQMQEKVKIKIYAMKIMKKNQIEQIKQEIHIMREINCFYKKINEKNILEQLNHPNIIKMYEC

GQ--YKHLFYLVLELTSNQNVLDFICRNRKNWDQK-----PFNNEFIRALSELSL----------------GLHQMSVSG-ILHRDIQTKNILISHSDQN
 |   .. .|||.|. . .. .|.|  |.|. ...     .|. . |. ...  |                .|. .   . |.||||   |||.      
FQEKDDNNIYLVMEYCQGGDLFDYIKNNKKKRNHEIEKDKYFTEKEIKYIMKQILQGFKTKAEFYIACIILALEYLHSKNNIIHRDIKPENILF------

FDYQNLTQLDKNCTLKICDFGLS
              .||.|||||
--------------IKIIDFGLS
Kinase 17861.AA TK-Unique 300-507 18 1.2e-20 68.0 In-house 1-233 (294) Show / Hide 
Range on Protein: 300-507
Range on HMM: 1-233/294
Sequence Identity: 18% (46 aa)

LDFTQQLGFGVQASVHKATYKG--------RPVAVKVYSLEKEKSQKIKCFLRELRALILSRHPNVVHLYGVGQYKH-LFYLVLELTSNQNVLDFICRNR
| . ...| |    |......|        . ||||    .  . .| . . .      | .|||.|...|. . .   .....|  ...| .... ..|
LEVGDVIGEGAFGQVWRGEVWGIWKHWDKQKCVAVKMLKDNATDTDKQDFLKEIQMMKELGDHPNIVQCLGCCTKSDEPWMIIMEYCPCGNLQHYLRTCR

KN-----------------WDQKP----FNNEFIRALSELSLGLHQMSV--SGILHRDIQTKNILISHSDQNFDYQNLTQLDKNCTLKICDFGLS-----
..                  |...        ... . ..  |.  ..    .| |||. ..|.|...               ....||||||..     
PAMRQHQTYGNLKFDFHHMPDKPRTEPISPKDLYHFAWQIACGMEYLASQRKKIVHRDLCARNVLLTE---------------DKVCKICDFGMARDVYT

-AIEEDKDSIVRGSTRHYSPESME-DKRNY-YPQSDVYMLGNSIWEMV
    . ..|  | . |. .|||.  ....| ...|||...|  .||..
NGVYSMMCSQGRIPIRWMAPESLKCYHGMYHTTKSDVWSFGVLMWEIF
Kinase 17861.AA CAMK 305-464 16 5.8e-19 57.07 In-house 1-245 (425) Show / Hide 
Range on Protein: 305-464
Range on HMM: 1-245/425
Sequence Identity: 16% (43 aa)

QLGFGVQASVHKATYK-G-------------RPVAVKVYSLEKEK--------------------------SQKIKCFLRELRALILSR-------HPNV
.|| |  . |.... |               . ||.|... .| |                           .. | ..||.. . . .       |||.
TLGRGSFGKVKLCIHKNTTGKERVHHIYTNGQKVAIKIIDKKKLKDKQNQDYSNCYKIDKSKCKHRYCWRRPKDRKNVRREIEIMKKLQGIGNKLDHPNI

VHLYG---------------VGQY-----KHLFYLVL---ELTSNQ----NVLDFICRNRK----------NWDQKPF-NNEFIRALSELSLGLHQMSVS
..||                  ..     .  .|.|.   |. |.      ..|.|.....            . . |   |  |    .  ..| .   
IKLYEVYEDPHYFKNTNDYET-SKQVFTKDKHMYMVMEIMEYCSGGELFDDLFDYIVEHGCYGEEFDQFDIV-ERGRFTEREARRYFRQICSAVHYCHSH

GILHRDIQTKNILISHSD--QN-------FDYQNLTQLDKNCTLKICDFGLSAI
.| |||.   |||.....  ..       ||        .|...||.|||....
NIVHRDLKPENILLDDNNDDSDPVEHDEIFD-------WNNNNIKIIDFGFANK
Kinase 17861.AA Pkinase_Tyr 300-507 24 1e-18 64.03 Pfam 1-208 (270) Show / Hide 
Range on Protein: 300-507
Range on HMM: 1-208/270
Sequence Identity: 24% (55 aa)

LDFTQQLGFGVQASVHKATYK------GRPVAVKVYSLEKEKSQK--IKCFLRELRALILS-RHPNVVHLYGVGQ-YKHL--FYLVLELTSNQNVLDFIC
. | ..|| |   .|.|.|.|      . |||||.   |.  ..   .. |.||.. .    .|||.| ||||    .     |.|.|.  . . ||.  
ITFGKKLGEGAFGEVYKGTWKGDPDNTKIPVAVKML-KEGAMHEQNCREDFMREAKIMKQLGHHPNIVRLYGVCTDQGEPNQIYIVMEYMPHGDLLDYLR

RNRKNWDQKPFNNEFIRALSELSLGLHQMSVSGILHRDIQTKNILISHSDQNFDYQNLTQLDKNCTLKICDFGLSAIEEDKDSI-VRGS-----TRHYSP
..| ...|..   . .    . . |.   .  .. |||. ..|.|...               | . |||||||.   ...|   . ..      . ..|
KHR-EDKQPLTMKDLLQMCWQIAKGMEYLESKNCIHRDLAARNCLVTE---------------NNVVKICDFGLARDIYNDDYYYRKRGGGKLPIKWMAP

ESMEDKRNYYPQSDVYMLGNSIWEMV
|.. ... .  .|||.. |  .||..
ECINYGK-FTTKSDVWSFGVLMWEIF
Kinase 17861.AA Dicty4 421-568 30 8.9e-12 35.73 In-house 135-277 (277) Show / Hide 
Range on Protein: 421-568
Range on HMM: 135-277/277
Sequence Identity: 30% (48 aa)

ILHRDIQTKNILISHSDQNFDYQNLTQLDKNCTLKICDFGLSA----IEEDKD--SIVRGSTRHYSPESMEDKRNYYPQSDVYMLGNSIWEMVYTKIIFT
|.|||. . |.|.               ||| . |.||||||.    .|. ||  . . |..   .|| |  .. |   .|||  |   ||..  .. . 
IIHRDLKSHNLLV---------------DKNWRVKVCDFGLSQYMKKHEDHKDNQMTACGTPCWMAPEVMMHQP-YNEKADVYSFGIVLWEILTRQEPYQ

--HSNVGEVHKTVIS-GEREEFDDKCPPEIQSVIEKCWKHNYLERPSFLEISND--LKQ
  |..  ..   | . ..| .  | ||| . . |..|| |.   |||| ||..   |  
KHHMPYMQFVRAVCNKKLRPPIPDWCPPSWKHLIQWCWDHDPQHRPSFEEIIQRRILEH
Kinase 17861.AA STE 420-561 18 3.3e-11 35.96 In-house 172-350 (359) Show / Hide 
Range on Protein: 420-561
Range on HMM: 172-350/359
Sequence Identity: 18% (36 aa)

GILHRDIQTKNILISHSDQNFDYQNLTQLDKNCTLKICDFGLSAIEED-------------------KDSIVRGSTRHYSPESMED-----KRNYYPQSD
.| ||||   |||.                     |.||||.... .|                   |   . |.  . .|| ..      .  |  ..|
HIIHRDIKPANILL--------------------VKLCDFGVCGQLTDSMANIQSNNIIDCIETMQQKRNTFVGTP-WMAPEVIQQNGQGRDKGYDTKCD

VYMLGNSIWEMVYTKIIFTH-SNVGEVHKTVIS--------------GEREEFDD-------------------KCPPEIQSVIEKCWKHNYLERPSFLE
.. ||  |.||.  |  .   ..      . ..              |.   . |                   |. || .  |.|| . .. .||.  .
IWSLGCTIIEMATGKPPWHDMHPMRAMFMIPFNYHMQQQFEQLCIVNGPPPPLPDHLSQNEMISYGGSGTTYPHKWSPEFKDFINKCLQKDPNKRPTASQ
Kinase 17861.AA STE 300-376 16 5.4e-11 35.18 In-house 1-118 (359) Show / Hide 
Range on Protein: 300-376
Range on HMM: 1-118/359
Sequence Identity: 16% (19 aa)

LDFTQQLGFGVQASVHKATYK-----------------GRPVAVKVYSLEKEKS---------------QKIKCFLRELRALILSR--HPNVVHLYGVGQ
... ...| |   .|.|| ..                 |. .|.|. .||....               .... .|.|.. .  ..  |||.|. ||   
WEGIEKIGKGAFGTVYKAMNHKNCNIHKTGEVENNGETGEIMAIKQMNLENCNNKDENQENQELENKNHEEMQQILKEIKIMKKCNHMHPNIVKYYGCYF

YK-------HLFYLVLEL
..       .  ....|.
KEGHNHKNDDELWICMEY
Kinase 17861.AA Dicty4 300-362 27 7.6e-11 32.59 In-house 1-65 (277) Show / Hide 
Range on Protein: 300-362
Range on HMM: 1-65/277
Sequence Identity: 27% (18 aa)

LDFTQQLGFGVQASVHKATYKGRPVAVKVYSLEKEK--SQKIKCFLRELRALILSRHPNVVHLYG
....| .| |  ..|.|.| .|  ||||.  . ...  .  .. |..|   .   ||||.. ..|
INIEQRIGKGSFGEVYKGTWRGKEVAVKKLNNHNQNFDENMLNEFRKEVHIMCKIRHPNICLFMG
Kinase 17861.AA ARK 300-364 33 2.5e-10 34.01 In-house 1-65 (280) Show / Hide 
Range on Protein: 300-364
Range on HMM: 1-65/280
Sequence Identity: 33% (22 aa)

LDFTQQLGFGVQASVHKATYKGRPVAVKVYSLEKEKSQKIKCFLRELRALILSRHPNVVHLYGVG
| .|  .| |  . | |..|.|..||.|| .     |..|  |. |.  . . | |.||..||..
LEYTCKIGSGSSCKVYKGKYRGKEVAIKVLKSIMTDSMQIEEFKKEFQIMSSIRSPHVVYFYGAC
Kinase 17861.AA Pkinase_Tyr 520-566 33 8.7e-10 33.77 Pfam 223-270 (270) Show / Hide 
Range on Protein: 520-566
Range on HMM: 223-270/270
Sequence Identity: 33% (16 aa)

EVHKTV-ISGEREEFDDKCPPEIQSVIEKCWKHNYLERPSFLEISNDL
|| . .  .|.| .  ..||.|| ... .||...  .||.| || ..|
EVYEYIYEDGYRMPCPENCPDEIYDLMKQCWHYDPEDRPTFSEIHEQL
Kinase 17861.AA LRRK 537-568 37 1.9e-08 25.96 In-house 315-351 (351) Show / Hide 
Range on Protein: 537-568
Range on HMM: 315-351/351
Sequence Identity: 37% (14 aa)

CPP-----EIQSVIEKCWKHNYLERPSFLEISNDLKQ
|||     . |. |..||.|. ..||.| .|   |.|
CPPCQPWHMYQDLIQHCWQHDPKKRPHFSQIVKRLSQ
Kinase 17861.AA TK-Unique 535-566 33 7.6e-08 23.26 In-house 262-294 (294) Show / Hide 
Range on Protein: 535-566
Range on HMM: 262-294/294
Sequence Identity: 33% (11 aa)

DKC-PPEIQSVIEKCWKHNYLERPSFLEISNDL
..| ..|. .... ||...  ||||| .| . |
EHCCSHEMYNLMKSCWQWEPEERPSFRQIKHRL
Kinase 17861.AA LRRK 300-364 14 1.1e-07 23.28 In-house 1-126 (351) Show / Hide 
Range on Protein: 300-364
Range on HMM: 1-126/351
Sequence Identity: 14% (18 aa)

LDFTQQLGFGVQA-SVHKATYKG----------------------------RPVAVKVYSL--------------------------------EKEKSQK
| . .|.| |. . .|..|...|                             .||.|.. .                                . ... .
LKIEEQIGRGGFGTFVYRAKWRGQPVHVCRMHQKMLQPYMYQGARNSYDMCQWVAIKKWNRDPMTIDNDCNNSNNNNNLNNNNSEQVEDMDQNHEDCCRA

IKCFLRELRALILSRHPNVVHLYGVG
   | .|.  .   .|||.| |.|..
FREFRHEVWIMSHLNHPNIVSLKGFC
Kinase 17861.AA ARK 413-462 34 0.000112 13.25 In-house 117-150 (280) Show / Hide 
Range on Protein: 413-462
Range on HMM: 117-150/280
Sequence Identity: 34% (17 aa)

LHQMSVSGILHRDIQTKNILISHSDQNFDYQNLTQLDKNCTLKICDFGLS
||..    |.|||. . |.|...               | |.|.||||||
LHNWTP-QIVHRDLKSLNLLVNE---------------NWTCKVCDFGLS
Kinase 17861.AA ARK 537-565 34 0.000228 12.12 In-house 252-280 (280) Show / Hide 
Range on Protein: 537-565
Range on HMM: 252-280/280
Sequence Identity: 34% (10 aa)

CPPEIQSVIEKCWKHNYLERPSFLEISND
||.   . | .|| ..  .|||  ||   
CPEQLKNLIQCCWDQDPDNRPSCEEIMEE
Kinase 17861.AA LRRK 421-462 36 0.00066 9.69 In-house 187-225 (351) Show / Hide 
Range on Protein: 421-462
Range on HMM: 187-225/351
Sequence Identity: 36% (16 aa)

ILHRDIQTKNILISHSDQNF--DYQNLTQLDKNCTLKICDFGLS
|.|||  . |||.  |.||.  .     ..  . . ||.|||.|
IIHRDLKSPNILLWSSPQNHSPN-----YPNAHVCAKIADFGIS