Gene 27908 (Tetrahymena)
27908
Group:
Other
Family:
Ciliate-D1
Sequence
Protein domains of 27908.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.
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| Domain | Protein name | Domain Name | Range | Identity (%) | Significance | Score | Profile Source | Profile Range (length) | Alignment |
|---|---|---|---|---|---|---|---|---|---|
| Kinase | 27908.AA | Ciliate-A5 | 99-130 | 21 | 0.01892 | 4.42 | In-house | 20-51 (275) | Show / Hide |
Range on Protein: 99-130 Range on HMM: 20-51/275 Sequence Identity: 21% (7 aa) IEKTFQDQNQLNEALKSVNLLQKIIHPNIINI . |..|| . . . .....||||... KQKQIQDEDRQKHFQQYFEQRMQLQHPNIVKL |
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| Kinase | 27908.AA | Ciliate-A5 | 155-276 | 22 | 3.3e-19 | 63.29 | In-house | 75-140 (275) | Show / Hide |
Range on Protein: 155-276 Range on HMM: 75-140/275 Sequence Identity: 22% (27 aa) YYSENLFSVLKKRKLIISQLNQKSSLSLNGDKKQEQSVPSSTSRSYSSQKKQSKQTYKKNPSSQVTPRGNQNSYVPAFTEKEIWYIIDSVVDTLNLLQQK |...||.. . .|| ...| |.|||.|... . .|||. YHDNNLEQEMQMRKQCQKD--------------------------------------------------------IFYNEQELWYIMDCLISVCMYLQQN SIIHGDLRPQTIFFTHDGHLKL |.|||.|||.|. | || .|| NICHGDIRPQNICLTQDGQVKL |
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| Kinase | 27908.AA | Ciliate-E4 | 232-278 | 40 | 2.8e-10 | 30.89 | In-house | 104-150 (150) | Show / Hide |
Range on Protein: 232-278 Range on HMM: 104-150/150 Sequence Identity: 40% (19 aa) FTEKEIWYIIDSVVDTLNLLQQKSIIHGDLRPQTIFFTHDGHLKLSI |.| ||| | . . . |||. | ||||.|. |||. |. FDESEIWQIAFCCINAMYYLQQVNITHGDLKPSNIFFDQYFMVKIAD |
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| Kinase | 27908.AA | SLK | 231-276 | 34 | 6.5e-07 | 19.22 | In-house | 93-138 (259) | Show / Hide |
Range on Protein: 231-276 Range on HMM: 93-138/259 Sequence Identity: 34% (16 aa) AFTEKEIWYIIDSVVDTLNLLQQKSIIHGDLRPQTIFFTHDGHLKL . ||. | |. ....|| | .. .|| ||. | .| ||...| PLTEDQIQYVCKHMCEALNWLHSNKVIHRDLKAGNILMTMDGDVRL |
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| Kinase | 27908.AA | Ciliate-E2b | 240-276 | 35 | 9.5e-07 | 16.71 | In-house | 107-143 (272) | Show / Hide |
Range on Protein: 240-276 Range on HMM: 107-143/272 Sequence Identity: 35% (13 aa) IIDSVVDTLNLLQQKSIIHGDLRPQTIFFTHDGHLKL .| |.. .| |....||..|. | | .|.|..|| YIASICLCLEYLHNQNIIYRDIKPENIMVDHKGYMKL |
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| Kinase | 27908.AA | Ciliate-A8 | 248-268 | 47 | 2e-06 | 18.86 | In-house | 123-143 (151) | Show / Hide |
Range on Protein: 248-268 Range on HMM: 123-143/151 Sequence Identity: 47% (10 aa) LNLLQQKSIIHGDLRPQTIFF |...|.|.|||.|. || |.. LLVFQEKGIIHCDIKPQNILY |
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| Kinase | 27908.AA | Ciliate-E2-Unclassified | 232-277 | 25 | 3e-06 | 17.52 | In-house | 135-189 (352) | Show / Hide |
Range on Protein: 232-277 Range on HMM: 135-189/352 Sequence Identity: 25% (14 aa) FTEKEIW-----YIIDSVVDTL-NLLQQKSIIHGDLRPQTIFFTHDG---HLKLS |||... ... ... | | ... ||| |. |. |.|. .| ..|.. FTEQQAKYKKAKFYFAQILQGLEYLHHKNNIIHRDIKPENILFDNNGKNYYIKII |
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| Kinase | 27908.AA | MSK | 232-277 | 38 | 6e-06 | 16.15 | In-house | 98-146 (277) | Show / Hide |
Range on Protein: 232-277 Range on HMM: 98-146/277 Sequence Identity: 38% (19 aa) FTEKEIWYIIDSVVDTLNLLQQKSIIHGDLRPQTIFFTHD---GHLKLS |.|.| .|. ..| . . || |||.|| | | |. . ||.||. FDESECRMIMRELVMAVDHMHQKGIIHRDLKPENILFDDEEDNGHVKLI |
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| Kinase | 27908.AA | Ciliate-E2 | 159-277 | 17 | 1.1e-05 | 15.53 | In-house | 120-198 (365) | Show / Hide |
Range on Protein: 159-277
Range on HMM: 120-198/365
Sequence Identity: 17% (23 aa)
NLFSVLKKRKLIISQLNQKSSLSLNGDKKQEQSVPSSTSRSYSSQKKQSKQTYKKNPSSQVTPRGNQNSYVPAFTEKEIWYIIDSVVD------------
.||. .|..|. . . . |||||| ||. ...
DLFDYIKNNKKKRNHEIE-------------------------------------------------K-D-KYFTEKEIKYIMKQILQGFKTKAEFYIAC
---TLNLLQQKS-IIHGDLRPQTIFFTHDGHLKLS
|. | .| ||| |. |. |.| .|..
IILALEYLHSKNNIIHRDIKPENILF-----IKII
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| Kinase | 27908.AA | Ciliate-C6 | 232-277 | 29 | 0.00388 | 6.97 | In-house | 132-179 (306) | Show / Hide |
Range on Protein: 232-277 Range on HMM: 132-179/306 Sequence Identity: 29% (14 aa) FTEKEIWYIIDSVVDTLNLLQQ-KSIIHGDLRPQTIFFTHD-GHLKLS |.|.|| . . .. || ... | | |. |. | . | .|| FDENEIVQFCKQIGKTLADIYNECNIAHRDIKPSNILIMDDENNYYLS |
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| Kinase | 27908.AA | TK-Unique | 251-277 | 31 | 0.089275 | 2.05 | In-house | 147-175 (294) | Show / Hide |
Range on Protein: 251-277 Range on HMM: 147-175/294 Sequence Identity: 31% (9 aa) LQQ--KSIIHGDLRPQTIFFTHDGHLKLS |.. | |.|.|| ...|.|. .|.. LASQRKKIVHRDLCARNVLLTEDKVCKIC |
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| Kinase | 27908.AA | Ciliate-C6 | 347-366 | 50 | 0.0079 | 5.86 | In-house | 225-244 (306) | Show / Hide |
Range on Protein: 347-366 Range on HMM: 225-244/306 Sequence Identity: 50% (10 aa) SNLEFDPYKSQVFSFGMLLL || . | .|. .||.||.|| SNQQIDYFKCDIFSLGMILL |
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| Kinase | 27908.AA | Ciliate-A5 | 344-367 | 41 | 0.034354 | 3.51 | In-house | 187-210 (275) | Show / Hide |
Range on Protein: 344-367 Range on HMM: 187-210/275 Sequence Identity: 41% (10 aa) QILSNLEFDPYKSQVFSFGMLLLQ | . . | . ||| ||. ||..|. QNIQRPEHNWYKSDVFCLGMICLE |
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| Kinase | 27908.AA | Ciliate-A5 | 418-458 | 26 | 1.3e-05 | 15.51 | In-house | 234-275 (275) | Show / Hide |
Range on Protein: 418-458 Range on HMM: 234-275/275 Sequence Identity: 26% (11 aa) VFDLLSQVKQ-MFSLSLYQILSTCLEAKEQKRPNCIELYNQL . ..| |.|. . | ... ... |. | |||. ...| .| LIKQLIQMKEKKYSEQFINFIKQMLQFEENKRPDFHQIYQYL |
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| Kinase | 27908.AA | TK-Unique | 433-458 | 19 | 1.9e-05 | 14.9 | In-house | 269-294 (294) | Show / Hide |
Range on Protein: 433-458 Range on HMM: 269-294/294 Sequence Identity: 19% (5 aa) LYQILSTCLEAKEQKRPNCIELYNQL .|.....|. ....||.. .. ..| MYNLMKSCWQWEPEERPSFRQIKHRL |
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