Gene 29013 (Tetrahymena)

29013

Species: Tetrahymena
Alias: PreTt29013, 29013, 77.m00225, 223, 3812.m02701, TTHERM_00577260
External Links: Tetrahymena Genome Database (TGD)
Annotation:

Classification

Group: Other
Family: Ciliate-D1

Sequence

Name Sequence Type Origin Length Description Download
29013.AA Protein None 1508 None Fasta, JSON
29013.kin_dom Protein Kinase Domain None 226 None Fasta, JSON
29013.NA RNA None 4527 None Fasta, JSON

Protein domain

Protein domains of 29013.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Kinase 29013.AA Ciliate-E2-Unclassified 1152-1292 19 7.9e-10 30.3 In-house 148-265 (352) Show / Hide 
Range on Protein: 1152-1292
Range on HMM: 148-265/352
Sequence Identity: 19% (30 aa)

IASYICDSLQNLHASS-IFHLNLKPSNILFDSKK---HPYLSGWEIRKKEKIQQAEENID---------DDEQDDKY-QVSYG--YTPPEVVNSINTQKP
.. .|.. |. || .  | | ..||.|||||...   .. .... | || . .. ..  .         .......    .|   ||.|||  . |  ..
YFAQILQGLEYLHHKNNIIHRDIKPENILFDNNGKNYYIKIIDFGISKKYQQNNNCD-TNQQQKMQIWKQQMMWTFCGTPNYMPQYTAPEVLQGQNYDHS

QVAMANNFSTPQKSQLASYATNSNPSFGPLNTVQALSQFGPNSDVWSLGMIFHYLFF
                                          .|.||||.|.... |
KA--------------------------------------YKCDIWSLGVILYEMLF
S_TKc 29013.AA S_TKc 1016-1359 12 3e-09 -41.32 SMART 1-231 (231) Show / Hide 
Range on Protein: 1016-1359
Range on HMM: 1-231/231
Sequence Identity: 12% (46 aa)

MISADKLSK------FRSYKKHMNISPEDQLILDGEPVVVKQFLISNPREVDEMFYFIESQEKKLMNQSSSINNQSTNVNSLAYQQHLAQVFLGQSLIYI
    .|. |      .. ..|.           .|. | .|.                                           .   |.       .|
YEILRKIGKGAFGKVYKCRHKK-----------TGRIVAIKIIK--------------------------------------EHIRREIQILKK-HHPNI

KGFSYQPVSNDAISLYLFYPAQSY---NLYGAMRKNL-------FSLLDKLLIASYICDSLQNLHASSIFHLNLKPSNILFDSKKHPYLSGWEIRKKEKI
  . .  ..    .||..    .    .|.  ..|.        |.  .   ..  ||. |. .|   | |  |||.|||.|.  |  ..   . ..   
VKLYDVFQD---DHLYMVMEYCDGDLGDLFDYIKKRGRHGLRFPFPE-HARFYMYQICCALEYCHSHGIIHRDLKPENILLDE--HIKICDFGLARQL--

QQAEENIDDDEQDDKYQVSYGYTPPEVVNSINTQKPQVAMANNFSTPQKSQLASYATNSNPSFGPLNTVQALSQFGP-NSDVWSLG-----MIFHYLFFR
             . . ..  | .|||.                                             ..|.  .|.||.|     |.  |  |.
-------------TTFCGTPWYMAPEVL---------------------------------------------GYGKCKCDWWSCGCILYEMLCGYPPFP

IDSGEGNFCRDKRVYAGFNLIITEYAIGSNYFLDKIKELIEDMVKSNPDQRATLSHVKD----LLQKLYI
             ... |..|            .  |..|. . . .|..| |   .        .  ..
------------QMQMMFKKIG----------SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF
Kinase 29013.AA TKL 1156-1354 11 1.9e-07 22.91 In-house 141-364 (364) Show / Hide 
Range on Protein: 1156-1354
Range on HMM: 141-364/364
Sequence Identity: 11% (29 aa)

ICDSLQNLHASS--------IFHLNLKPSNILFDSKKH--------------PYLSGWEIRKKEKIQQAEENIDDDEQ----------DDKYQV-SYGYT
|.  .. ||..         | | .||..||| |.. .              . ..   . .  .  .  . .  ...              |. .... 
IARGMNYLHSMNPKWCTKPPIIHRDLKSKNILVDENWTNVSNYMYNPNADWCCKICDFGLSRFMSQSGNMNDTMTTMMESAEHQNNRKTTMTQCGTPRWM

PPEVVNSINTQKPQVAMANNFSTPQKSQLASYATNSNPSFGPLNTVQALSQFGPNSDVWSLGMIFHYLFFRIDSGEGNFCR------------DKRVYAG
.||| .  .  .  | .                            ..  ... . .||.| |...  .. |    ... ..             .... |
APEVLRGQMNYTEKVGI-------------------------DE-FCKGFEYSEKCDVYSFGIVLWEILTRCRPYYDYPYMPMIFQDPFEEMFMMVCDKG

FNLIITEYAIG------SNYFLDKIKELIEDMVKSNPDQRATLSHVKDLL
  . | .           ..... .|.|..|  ...|..| . . ... |
LRPPIPPIWQNHHKMCPCPDCPPSMKKLMQDCWDHDPEKRPSFQEILKRL
Kinase 29013.AA Ciliate-C1 1158-1182 44 2.3e-07 14.57 In-house 140-164 (328) Show / Hide 
Range on Protein: 1158-1182
Range on HMM: 140-164/328
Sequence Identity: 44% (11 aa)

DSLQNLHASSIFHLNLKPSNILFDS
...| .| ..|.|. ||| |||.|.
NVIQYIHQNNICHRDLKPENILLDE
Kinase 29013.AA Ciliate-E1 1141-1243 22 1e-06 18.39 In-house 103-202 (202) Show / Hide 
Range on Protein: 1141-1243
Range on HMM: 103-202/202
Sequence Identity: 22% (24 aa)

KNLFSLLDKLLIASYICDSLQNLHASSIFHLNLKPSNILFDSKKHPYLSGWEIRKKEKIQQAE--ENIDDDEQDDKYQVSYGYTPPEVVN----SINTQK
.| |. . |. |.  . | |. ||.  | |...||.|||.....   ..        .....    | ...... |.. .| | |||..|    . | ..
QNQFTFQQKMQIIFQLIDGLIELHQYNIIHRDIKPQNILINNQGNYVYC--------DFGISKFLKNNQNQQCQYKGYTHY-YYPPEQYNCPEQEHNKNQ

PQVAMANNF
.   . . .
KINYKSDIY
Kinase 29013.AA Ciliate-B2 1158-1180 47 2e-06 11.17 In-house 115-137 (197) Show / Hide 
Range on Protein: 1158-1180
Range on HMM: 115-137/197
Sequence Identity: 47% (11 aa)

DSLQNLHASSIFHLNLKPSNILF
| |  ..   | || .||.||||
DGLIQFRMYNILHLDIKPQNILF
Kinase 29013.AA MLCK 1156-1184 37 3e-06 11.98 In-house 106-134 (257) Show / Hide 
Range on Protein: 1156-1184
Range on HMM: 106-134/257
Sequence Identity: 37% (11 aa)

ICDSLQNLHASSIFHLNLKPSNILFDSKK
||. .. .|   | ||.||| ||.. ...
ICEGVHHMHWQNIVHLDLKPENIMCQTRT
Kinase 29013.AA TKL-Sp1 1163-1182 40 5e-06 14.4 In-house 114-133 (263) Show / Hide 
Range on Protein: 1163-1182
Range on HMM: 114-133/263
Sequence Identity: 40% (8 aa)

LHASSIFHLNLKPSNILFDS
.||. | ||  ||.|.. ..
MHACNILHLDIKPANVMVER
Kinase 29013.AA CAMK 1156-1183 42 5.7e-05 11.18 In-house 188-215 (425) Show / Hide 
Range on Protein: 1156-1183
Range on HMM: 188-215/425
Sequence Identity: 42% (12 aa)

ICDSLQNLHASSIFHLNLKPSNILFDSK
||. .. .|   | |. ||| |||.|..
ICSAVHYCHSHNIVHRDLKPENILLDDN
Kinase 29013.AA Pkinase 1215-1359 11 0.000472 15.41 Pfam 171-293 (293) Show / Hide 
Range on Protein: 1215-1359
Range on HMM: 171-293/293
Sequence Identity: 11% (19 aa)

YQVSYGYTPPEVVNSINTQKPQVAMANNFSTPQKSQLASYATNSNPSFGPLNTVQALSQFGPNSDVWSLGMIFHYLFFRIDSGEGNFCRDK------RVY
. ....| .|||..                                           .  || .|.||.| |.......        ....      . .
FCGTPWYMAPEVIR-----------------------------------------GGQYYGPKVDMWSCGCILYEMLCGR-----PPFPGHCWHDNHDQM

AGFNLIITEYAIGSNYFL---------------------DKIKELIEDMVKSNPDQRATLSHVKDLLQKLYI
. ...|       . . .                     .  |..|... . .| .| |    ...||  ..
QMICRIMGPPLHFDWPWWCSISYFFFRHWHFHWTFHNWSEECKDFIKWCLCKDPKKRPT---AEQILQHPWF
Kinase 29013.AA ULK 1156-1179 41 0.001734 8.14 In-house 139-162 (329) Show / Hide 
Range on Protein: 1156-1179
Range on HMM: 139-162/329
Sequence Identity: 41% (10 aa)

ICDSLQNLHASSIFHLNLKPSNIL
|.  .. ||   | |  .||.|||
ILNGFKELHKHNIIHRDIKPQNIL
Kinase 29013.AA ULK 1156-1179 45 0.001757 8.29 In-house 135-158 (324) Show / Hide 
Range on Protein: 1156-1179
Range on HMM: 135-158/324
Sequence Identity: 45% (11 aa)

ICDSLQNLHASSIFHLNLKPSNIL
||  .. ||   | |  .||.|||
ICNGFKELHKHNIIHRDIKPQNIL
Kinase 29013.AA ULK 1278-1292 46 0.003302 7.15 In-house 237-251 (329) Show / Hide 
Range on Protein: 1278-1292
Range on HMM: 237-251/329
Sequence Identity: 46% (7 aa)

SDVWSLGMIFHYLFF
.|.||||.||... .
CDIWSLGCIFYEMLY
Kinase 29013.AA ULK 1278-1292 46 0.003577 7.18 In-house 233-247 (324) Show / Hide 
Range on Protein: 1278-1292
Range on HMM: 233-247/324
Sequence Identity: 46% (7 aa)

SDVWSLGMIFHYLFF
.|.||||.||... .
CDIWSLGCIFYEMLY
Kinase 29013.AA Ciliate-B2 1278-1284 57 0.023709 1.22 In-house 191-197 (197) Show / Hide 
Range on Protein: 1278-1284
Range on HMM: 191-197/197
Sequence Identity: 57% (4 aa)

SDVWSLG
||..|.|
SDIYSMG
Pkinase 29013.AA Pkinase 1138-1189 27 0.446042 4.89 Pfam 97-154 (293) Show / Hide 
Range on Protein: 1138-1189
Range on HMM: 97-154/293
Sequence Identity: 27% (16 aa)

AMRKNLF--SLLDKLLIASYICDSLQNLHASSIFHLNLKPSNILFDSKKHP----YLS
..|.. |  |  .   ..  |.  |. .|. .| |  |||.|||.|.. |.     ..
TWRHGCFYFSEWECKFYMYQILRGLEYCHSMGIIHRDLKPENILIDNNGHIDACVKIC