Gene 3331 (Tetrahymena)

3331

Species: Tetrahymena
Alias: 3740.m00054, 311, PreTt03331, 3331, TTHERM_00765390, 126.m00129
External Links: Tetrahymena Genome Database (TGD)
Annotation:

Classification

Group: Other
Family: Ciliate-D1

Sequence

Name Sequence Type Origin Length Description Download
3331.AA Protein None 1695 None Fasta, JSON
3331.kin_dom Protein Kinase Domain None 168 None Fasta, JSON
3331.NA RNA None 5088 None Fasta, JSON

Protein domain

Protein domains of 3331.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Kinase 3331.AA Ciliate-A5 230-301 25 9.5e-09 26.54 In-house 195-275 (275) Show / Hide 
Range on Protein: 230-301
Range on HMM: 195-275/275
Sequence Identity: 25% (21 aa)

NYYKMDVFSLGIVFLQLAQLE-I-YEGV----FNFKQS--KDFAIQKVGEIYGRNIKEFISLMLAPREE-RKDFIALEEIM
| || |||.|| . |... .. . ..      |    .   ...||.. . |. .  .||..||   |. |.||. .....
NWYKSDVFCLGMICLEMCTMRDCTQFYYDYETFQIQNNQLIKQLIQMKEKKYSEQFINFIKQMLQFEENKRPDFHQIYQYL
Kinase 3331.AA Ciliate-E1 63-237 20 0.000125 11.52 In-house 21-202 (202) Show / Hide 
Range on Protein: 63-237
Range on HMM: 21-202/202
Sequence Identity: 20% (38 aa)

KISEQRINNEIYMNQ-QAQGVNQNIIKVKGVVKQQS----IDDLTKQKQE-KFIILLSYVSQNLREVIE-------FKKIAKENQYFTPQELKAQMKSLI
.. .. || .. .|| . | ......|..  .|..     | |  |..|   .||.. .....| . ..       .... .....|| |.. . .. ||
QVAQKIINCCFNYNQNHFQDEIKEYYKIMK-FKKECYIIQIIDYIKIDQNYICIIIFECCCCSLKDYLQNHNRLEYWQQCQQNQNQFTFQQKMQIIFQLI

KTFADLQRNNIAHRRIELESIYFLNQNSSFQLGDFYYSKNLIGQEDSEIRQIDQTELFQMKFPDEKSLECLSNGMPELKSNY-YKMDVF
. ...|. .|| || |  . | . || . ... ||. ||.|. ......    | . .. ..  .  . |     .. . .. || |..
DGLIELHQYNIIHRDIKPQNILINNQ-GNYVYCDFGISKFLKNNQNQQC----QYKGYTHYYYPPEQYNCPEQ-EHNKNQKINYKSDIY
Kinase 3331.AA Ciliate-B2 232-240 33 0.004267 3.01 In-house 189-197 (197) Show / Hide 
Range on Protein: 232-240
Range on HMM: 189-197/197
Sequence Identity: 33% (3 aa)

YKMDVFSLG
.. |..|.|
FQSDIYSMG
Kinase 3331.AA Ciliate-E3 235-247 53 0.0162 4.01 In-house 190-202 (202) Show / Hide 
Range on Protein: 235-247
Range on HMM: 190-202/202
Sequence Identity: 53% (7 aa)

DVFSLGIVFLQLA
|  |.| ||.|| 
DYYSVGAVFCQLC
Kinase 3331.AA Ciliate-C8 233-243 45 0.042561 3.73 In-house 228-238 (238) Show / Hide 
Range on Protein: 233-243
Range on HMM: 228-238/238
Sequence Identity: 45% (5 aa)

KMDVFSLGIVF
| |..|.|.|.
KSDSYSVGLVL
Kinase 3331.AA C8 226-243 33 0.074411 2.36 In-house 209-226 (226) Show / Hide 
Range on Protein: 226-243
Range on HMM: 209-226/226
Sequence Identity: 33% (6 aa)

ELKSNYYKMDVFSLGIVF
..| .  . |.||.|.| 
QYKQYRIQSDLFSVGLVL
Kinase 3331.AA Ciliate-A1 231-247 35 0.094455 1.66 In-house 206-222 (301) Show / Hide 
Range on Protein: 231-247
Range on HMM: 206-222/301
Sequence Identity: 35% (6 aa)

YYKMDVFSLGIVFLQLA
| . |..|||.... |.
YKQSDMYSLGCIICFLC
Kinase 3331.AA Ciliate-E2 639-802 19 3.4e-18 59.03 In-house 140-365 (365) Show / Hide 
Range on Protein: 639-802
Range on HMM: 140-365/365
Sequence Identity: 19% (47 aa)

HNLTFLERLSIVKKLIL---------------TITDIHNLN-IAHGEIKPQNILLDLQKNPFLTDFVVCDK---------MIGPSQLIKSRGF-------
...|  |.. | |...                 .  .|. | | |  |||.|||.     ....||  . |         . .. . ..   .       
KYFTEKEIKYIMKQILQGFKTKAEFYIACIILALEYLHSKNNIIHRDIKPENILF-----IKIIDFGLSKKYDDDNQNRTH-KQQCKWYMF-KNDTSRTP

-----------------ETGYSAPEQYNDMQ---------FCKNSDIWSLGVIISEFLTGLKVDSYIVEKFGLYDPTRQGSLDLQQYGY-----------
                   || ||| .|  .           . .||||||||. |.|.|             ..   |. .|.... .           
GYMDQIIQQNMFNTICGTPGYMAPEILNGKKYDNQQKQKGYDYKCDIWSLGVILYEMLFGKPPF---------QQQIKQCKIDFPCPEWQKDTQCIQCKW

--FDNYNIS--MLIKQ----MTQYNPDNRLP-LNQVLEHINF
  ...   .   |||.    | |..|..|.   .|.|.|  |
KSWKKWSQECKDLIKKFGKRMLQKDPEKRITGWEQILNHPWF
Kinase 3331.AA Ciliate-E1 640-728 31 3.3e-17 52.89 In-house 105-202 (202) Show / Hide 
Range on Protein: 640-728
Range on HMM: 105-202/202
Sequence Identity: 31% (31 aa)

NLTFLERLSIVKKLILTITDIHNLNIAHGEIKPQNILLDLQKNPFLTDFVVCDKMI-GPSQLIKSRGFETGYSAPEQYN--------DMQFCKNSDIW
..||.. ..|.. ||  . ..|..|| |. ||||||| . |.|  ..|| .... .    | .. .|. . |. |||||        . .  ..||| 
QFTFQQKMQIIFQLIDGLIELHQYNIIHRDIKPQNILINNQGNYVYCDFGISKFLKNNQNQQCQYKGYTHYYYPPEQYNCPEQEHNKNQKINYKSDIY
Kinase 3331.AA Ciliate-E2-Unclassified 542-740 18 1.8e-16 53.64 In-house 16-281 (352) Show / Hide 
Range on Protein: 542-740
Range on HMM: 16-281/352
Sequence Identity: 18% (50 aa)

IKIQNSIGRGQRSEVRGCETKERN-------CCIAKMYY-KTKNTDVWEMLESLNKFYQC----------------VQNKNILVIQIEGY---YINPVKE
 ||.  ||.|. ..|. |. |. .        . ...|  | ...   |.. ...   .                 .........  . .   . |.   
YKIIKQIGQGGFGKVYKCQHKKQKQYYAMKYMKKIQIYKQKQIMNKD-EIMNEMKEMNNKKKYHQRKYNKIMQQILLNHPHPFIVKMFYCFQDKQNIYIV

NEYESELWLIQKQKKYNL---------ITIQLRHNLTFLERL-----SIVKKLILTITDIHNLN-IAHGEIKPQNILLDLQK---NPFLTDFVVCDKMIG
 ||   . |.|  ||..           ... |. .|  . .      . . ... .  .|  | | |  |||.|||.| ..   .. ..||  . | . 
MEYCEGGDLWQYIKKRKKQKQKGNDLFHNMKQRKIFTEQQAKYKKAKFYFAQILQGLEYLHHKNNIIHRDIKPENILFDNNGKNYYIKIIDFGISKKYQQ

P---------------SQLIKSRGFETGYS----APEQYNDMQFC----KNSDIWSLGVIISEFLTG
.               .|.....    .|     ||| .   .      . .||||||||. |.|.|
NNNCDTNQQQKMQIWKQQMMWTFCGTPNYMPQYTAPEVLQGQNYDHSKAYKCDIWSLGVILYEMLFG
Kinase 3331.AA Ciliate-B2 647-731 32 1.3e-15 33.12 In-house 107-197 (197) Show / Hide 
Range on Protein: 647-731
Range on HMM: 107-197/197
Sequence Identity: 32% (30 aa)

LSIVKKLILTITDIHNLNIAHGEIKPQNILLDLQKNPFLTDF-VVCDKMIGPSQLIKSRGFETGYSAPEQYNDM-------QFCKNSDIWSLG
. ..  ||   . ..  || | .|||||||.  . |  ..|| . . |     | || .||.  |  ||| ..        .    |||.|.|
YQMIFQLIDGLIQFRMYNILHLDIKPQNILFMQNGNYVYCDFGISSIKK--DNQQIKIKGFTKKYASPEQMECDHNQTFVTNIDFQSDIYSMG
Kinase 3331.AA S_TKc 542-802 16 1.1e-11 -5.49 SMART 1-231 (231) Show / Hide 
Range on Protein: 542-802
Range on HMM: 1-231/231
Sequence Identity: 16% (48 aa)

IKIQNSIGRGQRSEVRGCETKE--RNCCIAKMYYKTKNTDVWEMLESLNKFYQCVQNKNILVIQIEGYYINPVKENEYESELWLIQKQKKY---NLIT-I
 .| . ||.|  ..|. |  |.  | . | ..          |....  .  .    .   .... ... .        ..|...         .| . |
YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK---------EHIRREIQILKK---HHPNIVKLYDVFQD--------DHLYMVMEYCDGDLGDLFDYI

QLRHN------LTFLERLSIVKKLILTITDIHNLNIAHGEIKPQNILLDLQKNPFLTDFVVCDKMIGPSQLIKSRGFETGYSAPEQYNDMQFCK-NSDIW
. |        ..  .  .... ... .  .|...| |  .||.|||||   .  ..|| .. ..       ..      | |||     .. |  .|.|
KKRGRHGLRFPFPE-HARFYMYQICCALEYCHSHGIIHRDLKPENILLDE--HIKICDFGLARQL-------TTFCGTPWYMAPEVL---GYGKCKCDWW

SLGVIISEFLTGLK---VDSYIVEKFGLYDPTRQGSLDLQQYGYFDNYNISMLIKQMTQYNPDNRLPLNQVLE-------HINF
|.|.|. |.|.|      .  . .| |                         .|... |..|..|.   ..|.       |  |
SCGCILYEMLCGYPPFPQMQMMFKKIG-------------------SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF
Kinase 3331.AA C8 660-734 29 5.8e-11 34.4 In-house 139-226 (226) Show / Hide 
Range on Protein: 660-734
Range on HMM: 139-226/226
Sequence Identity: 29% (26 aa)

IHNLNIAHGEIKPQNILLDLQKNPF----LTDFVVCDKMIGPSQLIKSRGF----ETGYSAPEQYND-----MQFCKNSDIWSLGVII
||  || | .|||.|.|. |..|      | || . ..     . | |. .      .|.|||. ..      |. . ||..|.|.. 
IHCKNIMHRDIKPHNFLVCLDQNYGFEIKLCDFGFASQVSKNKSHIQSKKMNTCGTWAYFAPEIEKKQDNQYKQYRIQSDLFSVGLVL
Kinase 3331.AA Ciliate-C8 660-734 22 5.8e-09 28.59 In-house 135-238 (238) Show / Hide 
Range on Protein: 660-734
Range on HMM: 135-238/238
Sequence Identity: 22% (23 aa)

IHNLNIAHGEIKPQNILLDLQ-KNPF---LTD------FVVCDKMIGPSQ-LIKSR---GFET---------GYSAPEQYND------MQFCKNSDIWSL
.|  || |  |||.|.|. .. .. .   | |      |   ...      .. .      ..         ||.|||....       .|.|.||..|.
LHCFNIMHRDIKPHNFLVCFDQQYQPTIKLCDFKKQCDFGFASQLPKNKSHYHSKKFKGTDQYIEMYFCGNWGYFAPEVEKKQSRIQSDIFSKKSDSYSV

GVII
|.. 
GLVL
Kinase 3331.AA CAMK 660-733 21 2.1e-08 22.43 In-house 195-323 (425) Show / Hide 
Range on Protein: 660-733
Range on HMM: 195-323/425
Sequence Identity: 21% (28 aa)

IHNLNIAHGEIKPQNILLDLQK-----------------NPFLTDFVVCDKMIG-----------------------PSQLIKSRGFETGYSA-PEQYND
.|..||.|  .|| |||||  .                 |  ..||    |...                       . |. | .    .| | ||  | 
CHSHNIVHRDLKPENILLDDNNDDSDPVEHDEIFDWNNNNIKIIDFGFANKFDPGENNFMCSDYKGGEMHNQWTTPTEGQKMKTFCGTPEYMAAPEVLNG

MQ--------------FCKNSDIWSLGVI
 .                . .|.||.|||
KGHCNMQNATDEEKPYYGPKCDMWSCGVI
Kinase 3331.AA Ciliate-E3 710-738 37 2e-06 16.59 In-house 174-202 (202) Show / Hide 
Range on Protein: 710-738
Range on HMM: 174-202/202
Sequence Identity: 37% (11 aa)

YSAPEQYNDMQFCKNSDIWSLGVIISEFL
|.||||    |. | ||. |.|... .  
YAAPEQNDQQQISKESDYYSVGAVFCQLC
Kinase 3331.AA Ciliate-E3 649-678 46 1.3e-05 13.82 In-house 108-137 (202) Show / Hide 
Range on Protein: 649-678
Range on HMM: 108-137/202
Sequence Identity: 46% (14 aa)

IVKKLILTITDIHNLNIAHGEIKPQNILLD
|....|  . .||  || |. |||.|||.|
ICIQIIQGMIAIHEKNIIHSDIKPDNILVD
Kinase 3331.AA Ciliate-A1 775-803 34 8.8e-05 12.13 In-house 273-301 (301) Show / Hide 
Range on Protein: 775-803
Range on HMM: 273-301/301
Sequence Identity: 34% (10 aa)

ISMLIKQMTQYNPDNRLPLNQVLEHINFL
.  ||..| ||.| ||. | |...    .
LQNLIFKMMQYEPNNRCSLQQCIDCLYIF
Kinase 3331.AA Pkinase 660-740 26 0.000106 17.71 Pfam 124-208 (293) Show / Hide 
Range on Protein: 660-740
Range on HMM: 124-208/293
Sequence Identity: 26% (23 aa)

IHNLNIAHGEIKPQNILLDLQKNP----FLTDFVVCDKM-IGPSQLIKSRGFETGYSAPEQYN-DMQFCKNSDIWSLGVIISEFLTG
.|. .| |  .||.|||.| . ..     ..|| .. .. . ...  ...    .| |||  . .    . .|.||.|.|. |.|.|
CHSMGIIHRDLKPENILIDNNGHIDACVKICDFGLAKQFDY-NNS-MTTFCGTPWYMAPEVIRGGQYYGPKVDMWSCGCILYEMLCG
Kinase 3331.AA Ciliate-E2-Unclassified 778-802 36 0.000871 9.04 In-house 328-352 (352) Show / Hide 
Range on Protein: 778-802
Range on HMM: 328-352/352
Sequence Identity: 36% (9 aa)

LIKQMTQYNPDNRLPLNQVLEHINF
|...| ..||..|. ..|.|.|  |
LLQKMLKKNPNKRITFEQILNHPWF
Kinase 3331.AA Ciliate-A1 649-677 48 0.001392 7.99 In-house 106-134 (301) Show / Hide 
Range on Protein: 649-677
Range on HMM: 106-134/301
Sequence Identity: 48% (14 aa)

IVKKLILTITDIHNLNIAHGEIKPQNILL
|  ..|  . |||  || |  .||||||.
ICYQIIEGYADIHDHNILHRDLKPQNILI
Kinase 3331.AA Ciliate-A1 710-736 36 0.001678 7.71 In-house 185-220 (301) Show / Hide 
Range on Protein: 710-736
Range on HMM: 185-220/301
Sequence Identity: 36% (13 aa)

YSAPEQ----Y-----NDMQFCKNSDIWSLGVIISE
| .|||    |      .    | ||..|||.|| .
YMSPEQYQMHYRDQMFIENKIYKQSDMYSLGCIICF
Kinase 3331.AA CAMK 778-802 36 0.002928 5.56 In-house 401-425 (425) Show / Hide 
Range on Protein: 778-802
Range on HMM: 401-425/425
Sequence Identity: 36% (9 aa)

LIKQMTQYNPDNRLPLNQVLEHINF
||..| |..|..|. . |.|.|  .
LIRKMLQVDPEKRMTIEQCLNHPWM
Kinase 3331.AA CAMK 547-579 21 0.010502 3.74 In-house 11-56 (425) Show / Hide 
Range on Protein: 547-579
Range on HMM: 11-56/425
Sequence Identity: 21% (10 aa)

SIGRGQRSEVRGCETKERNC-------------CIAKMYYKTKNTD
 .|||. ..|. |. |. ..             . .|.. |.| .|
TLGRGSFGKVKLCIHKNTTGKERVHHIYTNGQKVAIKIIDKKKLKD
Kinase 3331.AA Ciliate-A5 664-677 71 0.013544 4.93 In-house 119-132 (275) Show / Hide 
Range on Protein: 664-677
Range on HMM: 119-132/275
Sequence Identity: 71% (10 aa)

NIAHGEIKPQNILL
|| || |.||||.|
NICHGDIRPQNICL
Kinase 3331.AA Pkinase 778-800 28 4.442809 1.36 Pfam 269-293 (293) Show / Hide 
Range on Protein: 778-800
Range on HMM: 269-293/293
Sequence Identity: 28% (7 aa)

LIKQMTQYNPDNRLPLNQVLEH--I
.|| . ...|  |.   |.|.|  .
FIKWCLCKDPKKRPTAEQILQHPWF