7822

Species: Tetrahymena
Alias: 7822, PreTt07822, TTHERM_00989320, 185.m00043, 851
External Links: Tetrahymena Genome Database (TGD)
Annotation:

Classification

Group: Other
Family: Ciliate-D1

Sequence

Name Sequence Type Origin Length Description Download
7822.AA Protein None 694 None Fasta, JSON
7822.kin_dom Protein Kinase Domain None 244 None Fasta, JSON
7822.NA RNA None 2085 None Fasta, JSON

Protein domain

Protein domains of 7822.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Kinase 7822.AA Ciliate-E2 84-244 17 1.8e-16 53.0 In-house 11-253 (365) Show / Hide
Range on Protein: 84-244
Range on HMM: 11-253/365
Sequence Identity: 17% (44 aa)

NFSQVYICKLDKQEQQS----------------SNDAQQFQDKSYVLKRVELTGDYQSEL----------LEPSFQFILKHENIASIIDYQV--INNQLE
||..|| || .|. .|.                 ......  |..  . .| .   ....           | . ...|.| ||  ....     .| . 
NFGSVYKCKVWKVQKQFAIKIIDQKQQRQQMQEKVKIKIYAMKIMKKNQIEQIKQEIHIMREINCFYKKINEKNILEQLNHPNIIKMYECFQEKDDNNIY

ILMDYYPEGSIVNYLQKNQEWP-----------WLERLKIFVNITN---------------CVQFIHYNE-LIHKDLKLLNILIDSKGKPSITDFGISE-
. |.|.  |.   |...|. .            . |...|.  |..               .....| .   || |.|. |||.     . |.|||.|  
LVMEYCQGGDLFDYIKNNKKKRNHEIEKDKYFTEKEIKYIMKQILQGFKTKAEFYIACIILALEYLHSKNNIIHRDIKPENILF-----IKIIDFGLSKK

----------LQACKQIQQNK----------------------YGTAKY
          .| || ... |                      .||. |
YDDDNQNRTHKQQCKWYMF-KNDTSRTPGYMDQIIQQNMFNTICGTPGY

Kinase 7822.AA NuaK 156-228 34 3.6e-16 38.48 In-house 76-148 (252) Show / Hide
Range on Protein: 156-228
Range on HMM: 76-148/252
Sequence Identity: 34% (25 aa)

ILMDYYPEGSIVNYLQKNQEWPWLERLKIFVNITNCVQFIHYNELIHKDLKLLNILIDSKGKPSITDFGISEL
| | |   |   .|. . .. |  |  ..|  |.  | . | .. .| |||| ||| | ..   | ||| | .
IVMEYASGGELYDYISECKSLPEREARHFFRQIVSAVHYCHKHRICHRDLKLENILLDQNCNAKIADFGLSNY

Kinase 7822.AA TKL 136-273 19 4.6e-14 47.05 In-house 82-282 (364) Show / Hide
Range on Protein: 136-273
Range on HMM: 82-282/364
Sequence Identity: 19% (41 aa)

LKHENIASIIDYQVINNQ-------------LEILMDYYPEGSIVNYLQKNQEWPWLERLKIFVNITNCVQFIHYNE--------LIHKDLKLLNILIDS
|.|.|| ... |   ...             | | |.|.| ||  .||.      |  |...   |   ... | ..        .|| |||  |||.|.
LRHPNIVQFMGYCCCPPCGCVCMHPVGPWGQLCIVMEYCPGGSLLHYLH------WHQRCRWALDIARGMNYLHSMNPKWCTKPPIIHRDLKSKNILVDE

KGK--------------PSITDFGISELQACKQ--------------------IQQNKYGTAKYSGKEF---QLDSN-----------MNLDDRSDIYSI
...              . |.|||.|     ..                       .. ||  .   |    |.. .              . ..|.|| 
NWTNVSNYMYNPNADWCCKICDFGLSRFMSQSGNMNDTMTTMMESAEHQNNRKTTMTQCGTPRWMAPEVLRGQMNYTEKVGIDEFCKGFEYSEKCDVYSF

AVILVEL
...| |.
GIVLWEI

Kinase 7822.AA Ciliate-B2 137-267 26 1.8e-13 27.97 In-house 58-197 (197) Show / Hide
Range on Protein: 137-267
Range on HMM: 58-197/197
Sequence Identity: 26% (38 aa)

KHENIASIIDYQVINNQLEILMDYYPEGSIVNYLQ---KNQ-EWPWLERLKIFVNITNCVQFIHYNELIHKDLKLLNILIDSKGKPSITDFGISELQACK
...|.  .||.  ||.. ..|     | |  . ||   | | . .    .... .  .    .. .. .| |.|  |||. ..|.   .||||| .    
YNINVVKYIDHIQINETIDVLIMEKCECSLKQELQKIQKQQKCFNNQKLYQMIFQLIDGLIQFRMYNILHLDIKPQNILFMQNGNYVYCDFGISSIKKDN

QIQQNKYGTAKYSGKEFQLDSN------MNLDDRSDIYSIA
| .. |  | ||  .| |..         |.|..|||||. 
QQIKIKGFTKKYASPE-QMECDHNQTFVTNIDFQSDIYSMG

Kinase 7822.AA Ciliate-E1 132-264 25 3.7e-13 39.57 In-house 49-202 (202) Show / Hide
Range on Protein: 132-264
Range on HMM: 49-202/202
Sequence Identity: 25% (40 aa)

FQFILKHENIASIIDYQV-INNQLEILMDYYPEGSIVNYLQ-------------KNQEWPWLERLKIFVNITNCVQFIHYNELIHKDLKLLNILIDSKGK
.. . |...|  ||||.   .|...|.   . . |  .|||             .....  .. ..|....   .. .|.. .|| |.|  ||||...|.
MK-FKKECYIIQIIDYIKIDQNYICIIIFECCCCSLKDYLQNHNRLEYWQQCQQNQNQFTFQQKMQIIFQLIDGLIELHQYNIIHRDIKPQNILINNQGN

PSITDFGISELQACKQIQQN--KYGTAKYSGKEFQL------DSNMNLDDRSDIY
  ..||||| ..  .|.||   |. | .|. .|         . | . .  ||||
YVYCDFGISKFLKNNQNQQCQYKGYTHYYYPPEQYNCPEQEHNKNQKINYKSDIY

S_TKc 7822.AA S_TKc 74-327 19 1.3e-12 7.86 SMART 1-231 (231) Show / Hide
Range on Protein: 74-327
Range on HMM: 1-231/231
Sequence Identity: 19% (52 aa)

VKDQTLLMKTNFSQVYICKLDKQEQQSSNDAQQFQDKSYVLKRVELTGDYQSELLEPSFQFILKHENIASIIDYQVINNQLEILMDYYPE--GSIVNYLQ
 .   .. |  |..|| |.  |             .. . .|..      .. . | .     .|.||  ..|. .  . | . |.| .   |.   |..
YEILRKIGKGAFGKVYKCRHKK------------TGRIVAIKIIK-----EHIRREIQILKK-HHPNIVKLYDVFQD-DHLYMVMEYCDGDLGDLFDYIK

KNQE------WPWLERLKIFVNITNCVQFIHYNELIHKDLKLLNILIDSKGKPSITDFGISELQACKQIQQNKYGTAKYSGKEFQLDSNMNLDD-RSDIY
|..        |  .  ...  | . ....| .  || |||  |||.|.     |.|||.. .           ||  |   |         .  ..|..
KRGRHGLRFPFPE-HARFYMYQICCALEYCHSHGIIHRDLKPENILLDE--HIKICDFGLARQL------TTFCGTPWYMAPEVL-----GYGKCKCDWW

SIAVILVELTLQRGIYQKEVSQSVDLTKEKGLLSDDALDFLKGMIDYSSKQVRPNSQEVNS---------FF
|. .|| |.   .  ..      .... .| . |..|.||.... ..  .. ||   |.           .|
SCGCILYEMLCGYPPFP-----QMQMMFKKIG-SPEAKDFIRKCLQKDPEK-RPTA-EALQDEWDIKCHPWF

Kinase 7822.AA GIN4 135-248 28 3.1e-11 31.72 In-house 90-204 (293) Show / Hide
Range on Protein: 135-248
Range on HMM: 90-204/293
Sequence Identity: 28% (33 aa)

ILKHENIASIIDYQVINNQLEILMDYYPEGSIVNYLQKNQEWPWLERLKIFVNITNCVQFIHYNELIHKDLKLLNILIDSKGK-PSITDFGISELQACKQ
.. | |. .. |    ||.| ....|  .| . ||| .  . |  | ...|  |   | . |  ...|.|||  |.|.|.| .   | |||.  |.   .
LISHPNVMRLYDVWETNNDLYLVLEYAEKGELFNYLVDHGPLPEREAIHYFRQIIIGVSYCHAFNICHRDLKPENLLLDHKYNRIKIADFGMAALETDNK

IQQNKYGTAKYSGKE
. .   |   |   |
LLETSCGSPHYAAPE

Kinase 7822.AA Ciliate-E2-Unclassified 182-244 27 4.5e-11 34.67 In-house 146-228 (352) Show / Hide
Range on Protein: 182-244
Range on HMM: 146-228/352
Sequence Identity: 27% (23 aa)

LKIFVNITNCVQFIHYNE-LIHKDLKLLNILIDSKG---KPSITDFGIS-ELQAC---------------KQIQQNKYGTAKY
...|  | .. ...|..   || |.|. |||.|..|   .. |.||||| ..| .               .|... . ||  |
KFYFAQILQGLEYLHHKNNIIHRDIKPENILFDNNGKNYYIKIIDFGISKKYQQNNNCDTNQQQKMQIWKQQMMWTFCGTPNY

Kinase 7822.AA C8 171-270 22 1.8e-10 32.65 In-house 115-226 (226) Show / Hide
Range on Protein: 171-270
Range on HMM: 115-226/226
Sequence Identity: 22% (25 aa)

QKNQEWPWLERLKIFVNITNCVQFIHYNELIHKDLKLLNILIDSKGKPS----ITDFGISEL--QACKQIQQNKY---GTAKYSGKEFQLD---SNMNLD
.|.|. .  ....| . .  .| .||  . .|.|.|. |.|.  ...      . |||..    . ...||. |.   || .|.  |   .    .    
NKQQQFSKEMKEIIAIQMIDGVNYIHCKNIMHRDIKPHNFLVCLDQNYGFEIKLCDFGFASQVSKNKSHIQSKKMNTCGTWAYFAPEIEKKQDNQYKQYR

DRSDIYSIAVIL
 .||..|. ..|
IQSDLFSVGLVL

Kinase 7822.AA Ciliate-E3 156-274 26 2.3e-10 28.85 In-house 81-202 (202) Show / Hide
Range on Protein: 156-274
Range on HMM: 81-202/202
Sequence Identity: 26% (34 aa)

ILMDYYPEGSIVNYLQKNQEWPWLERLKIFVNITNCVQFIHYNELIHKDLKLLNILIDSKG---KPSITDFGISELQACKQIQQNK-----Y---GTAKY
| ..|   |.  .|..  |.    . ..|. .|.  .  ||   .|| |.|  |||.|.        | ||| |     || ..||     .    |  |
IVQEYCSNGDLYHYIK-QQNKTQNIIYDICIQIIQGMIAIHEKNIIHSDIKPDNILVDKNNNQLIIKICDFGES-----KQLRKNKGHTHTQYQGWTPFY

SGKEFQLDSNMNLDDRSDIYSIAVILVELT
. .|    ..  .   ||.||. ... .| 
AAPEQNDQQQISKE--SDYYSVGAVFCQLC

Kinase 7822.AA Kin4 156-224 33 4.9e-10 26.37 In-house 87-155 (273) Show / Hide
Range on Protein: 156-224
Range on HMM: 87-155/273
Sequence Identity: 33% (23 aa)

ILMDYYPEGSIVNYLQKNQEWPWLERLKIFVNITNCVQFIHYNELIHKDLKLLNILIDSKGKPSITDFG
| ..|   |    |.|.       .  ..|  .   |...||  |.|.|||| |.|.| .    |||||
IVLEYVCGGEFYKYIQRKRRLKEMNACRLFAQLISGVHYMHYKGLVHRDLKLENLLLDKHENLVITDFG

Kinase 7822.AA Pkinase 136-228 25 5.8e-10 36.31 Pfam 57-161 (293) Show / Hide
Range on Protein: 136-228
Range on HMM: 57-161/293
Sequence Identity: 25% (27 aa)

LKHENIASIIDYQVINNQLEILMDYYPEG----SIVNYLQ--KNQEW--PWLERLKIFVNITNCVQFIHYNELIHKDLKLLNILIDSKGKP----SITDF
|.|.||  ..|.   .. . . |.| . |    .   |..  ..     .. |  ...  |   ....| .  || |||. |||||..| .     |.||
LNHPNIVRLYDWFEDKDHIYMVMEYCEGGLYVMDLFDYISTWRHGCFYFSEWECKFYMYQILRGLEYCHSMGIIHRDLKPENILIDNNGHIDACVKICDF

GISEL
|....
GLAKQ

TyrKc 7822.AA TyrKc 74-327 17 9.9e-07 -113.81 SMART 1-280 (280) Show / Hide
Range on Protein: 74-327
Range on HMM: 1-280/280
Sequence Identity: 17% (55 aa)

VKDQTLLMKTNFSQVYICKLDKQEQQSSNDAQQFQDKSYVLKRV---ELTGDYQSELLEPSFQFI--------L--KHENIASIIDYQVIN-------NQ
..    |   .| .|| ....                      |    |  |           |.        |  .|.||  .. . .          .
ITLGKKLGEGAFGEVYKGTWK--------------------IQVAVKMLKEDA-------REDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEP

LEILMDYYPEGSIVNYLQKNQE-WPWLERLKIFVNITNCVQFIHYNELIHKDLKLLNILIDSKGKPSITDFGISELQACK---QIQQNKYGTAKY--SGK
| |.| | | |.  .||.|...  .. . |.. . | .  ...| . .|| ||   |.|.....   |.||| |     .        .| ..|   .||
LMIVMEYMPHGDLKDYLRKHRPKLCMKDLLSFCWQIACGMEYLHSKNCIHRDLAARNCLVGENHTVKISDFGLSRDIYDDDQQG-ESKDYYRKKEHKGGK

----------EFQLDSNMNLDDR-----SDIYSIAVILVEL-----TLQRG-----IYQKEVSQSVD----LTKEKGL-------LSDDALDFLKGMIDY
          |        ....     ||..|  | . |.     .   |     .  .|| . |.    . . .          .|.  .  |   ..
TMLPIRWMAPE-------CINYGKFTTKSDVWSFGVCMWEIFTYGQQPYPGMIQQMMSNQEVIEYVKQGYRMPQPPNDYPMSFVCCPDEMYQIMKQCWHE

SSKQVRPNSQEVNSFF
  .. ||. .|. ..|
DPED-RPTFSEIHECF

Kinase 7822.AA Pkinase 260-327 15 1.223863 3.34 Pfam 192-293 (293) Show / Hide
Range on Protein: 260-327
Range on HMM: 192-293/293
Sequence Identity: 15% (16 aa)

RSDIYSIAVILVELTLQRGIYQKE-----VSQSVDLTKEKG----------------------------LLSDDALDFLKGMIDYSSKQVRPNSQEVNSF
..|..|. .|| |. . | ... .     ..| . . . .|                            ..|....||.|.....  |. ||. ...   
KVDMWSCGCILYEMLCGRPPFPGHCWHDNHDQMQMICRIMGPPLHFDWPWWCSISYFFFRHWHFHWTFHNWSEECKDFIKWCLCKDPKK-RPTAEQILQH

--F
  |
PWF