13481

Species: Tetrahymena
Alias: 13481, TTHERM_00369590, 1137, 38.m00316, PreTt13481
External Links: Tetrahymena Genome Database (TGD)
Annotation:

Classification

Group: Other
Family: Ciliate-E1

Sequence

Name Sequence Type Origin Length Description Download
13481.AA Protein None 821 None Fasta, JSON
13481.kin_dom Protein Kinase Domain None 86 None Fasta, JSON
13481.NA RNA None 2466 None Fasta, JSON

Protein domain

Protein domains of 13481.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Kinase 13481.AA Ciliate-A8 33-117 46 1.4e-28 96.03 In-house 1-85 (151) Show / Hide
Range on Protein: 33-117
Range on HMM: 1-85/151
Sequence Identity: 46% (40 aa)

YVYEKQISRSSSSLVVQAKSLNHNNSNVAIKILNY-KYNSKINSQKLSKQVDFLDNLKGEKYVLQFIERIQDLNQGITAIVTEYCE
|.|.| .     |.||||.|.||.. .|||||..| .   ||| ... |..  . ..|.|||.||.|| |||..|| .|||||.|.
YKYQKVLEKGDFSYVVQAYSINHQC-QVAIKIIKYMNQQNKINDKEFEKCIQAMQKIKNEKYILQIIECIQDKEQGFIAIVTEFCD

Kinase 13481.AA Ciliate-E1 39-120 31 1.5e-22 70.45 In-house 1-84 (202) Show / Hide
Range on Protein: 39-120
Range on HMM: 1-84/202
Sequence Identity: 31% (27 aa)

ISRSSSSLVVQAKSLNHNNSNVAIKILNYKYN-SKINSQKLSKQVD-FLDNLKGEKYVLQFIERIQ-DLNQGITAIVTEYCERLL
|...|.|.|..||. |.|...||.|| |...| .... |...|. . ... .|.|.|..|.|. |. |.|.....|....|..|.
IGNGSFSIVFKAKQQNNNYNQVAQKIINCCFNYNQNHFQDEIKEYYKIMK-FKKECYIIQIIDYIKIDQNYICIIIFECCCCSLK

Kinase 13481.AA Ciliate-E2-Unclassified 132-198 21 8.1e-10 30.25 In-house 170-262 (352) Show / Hide
Range on Protein: 132-198
Range on HMM: 170-262/352
Sequence Identity: 21% (20 aa)

IEPEKILYSAQNN--QFLLSYLSFSR-----------------LIQFEGNEKQQGNLNYQ----SPEVINKKKPYK---ITADIFSIGVILLE
| || ||.. ...  .  .. ...|.                  ....    . |..||.    .|||. ......   . .||.| |||| |
IKPENILFDNNGKNYYIKIIDFGISKKYQQNNNCDTNQQQKMQIWKQQMMWTFCGTPNYMPQYTAPEVLQGQNYDHSKAYKCDIWSLGVILYE

Kinase 13481.AA S_TKc 33-234 14 1.6e-08 -51.9 SMART 1-231 (231) Show / Hide
Range on Protein: 33-234
Range on HMM: 1-231/231
Sequence Identity: 14% (37 aa)

YVYEKQISRSSSSLVVQAKSLNHNNSNVAIKILNYKYNSKINSQKLSKQVDFLDNLKGEKYVLQFIERIQDLNQGITAIVTEYCER-----LLLIQEKQK
|   ..| . . . | ...  .  .  |||||..         ... . .. | .  . ... .... .||   .   .|.|||.      . .|.....
YEILRKIGKGAFGKVYKCRHKK-TGRIVAIKIIK---------EHIRREIQILKK--HHPNIVKLYDVFQD---DHLYMVMEYCDGDLGDLFDYIKKRGR

VLR---YIEPEKILYSAQ--------------------------NNQFLLSYLSFSRLIQFEGNEKQQGNLNYQSPEVINKKKPYKI-TADIFSIGVILL
  .   . | .   | .|                          . .  ..   ..|..       . | ..| .|||.    .|    .|. |.|.|| 
HGLRFPFPE-HARFYMYQICCALEYCHSHGIIHRDLKPENILLDE-HIKICDFGLARQL-----TTFCGTPWYMAPEVL----GYGKCKCDWWSCGCILY

EALL-----QRKLKGMEYLKLKSQSLISVLPDLLNEQ----------N-------HQFI
| |      .  .. |  . . |..... .  .|.            .       |...
EMLCGYPPFP-QMQMMFKKIG-SPEAKDFIRKCLQKDPEKRPTAEALQDEWDIKCHPWF

Kinase 13481.AA C8 122-196 25 1.9e-08 25.58 In-house 139-226 (226) Show / Hide
Range on Protein: 122-196
Range on HMM: 139-226/226
Sequence Identity: 25% (22 aa)

IQEKQKVLRYIEPEKILYSAQNNQF---LLSYLSFSRLIQFEGN--EKQQ----GNLNYQSPEVINK----KKPYKITADIFSIGVIL
|. |. . | | |. .|  ...|.     |. . |.  .. . .  . ..    |.. |  ||...|     | |.|  |.||.|..|
IHCKNIMHRDIKPHNFLVCLDQNYGFEIKLCDFGFASQVSKNKSHIQSKKMNTCGTWAYFAPEIEKKQDNQYKQYRIQSDLFSVGLVL

Kinase 13481.AA Ciliate-E2 157-196 35 4e-07 20.5 In-house 239-286 (365) Show / Hide
Range on Protein: 157-196
Range on HMM: 239-286/365
Sequence Identity: 35% (17 aa)

IQFEGNEKQQGNLNYQSPEVINKKKP--------YKITADIFSIGVIL
||..    . |...|..||..|.||         |   .||.|.||||
IQQNMFNTICGTPGYMAPEILNGKKYDNQQKQKGYDYKCDIWSLGVIL

Kinase 13481.AA CAMK1 171-196 50 8.7e-07 15.69 In-house 179-206 (276) Show / Hide
Range on Protein: 171-196
Range on HMM: 179-206/276
Sequence Identity: 50% (14 aa)

YQSPEVINKK--KPYKITADIFSIGVIL
|. |||.. |  |||  . |..|||||.
YVAPEVLECKKDKPYDKACDMWSIGVIT

Kinase 13481.AA Ciliate-E1 132-190 20 2e-06 17.38 In-house 135-202 (202) Show / Hide
Range on Protein: 132-190
Range on HMM: 135-202/202
Sequence Identity: 20% (14 aa)

IEPEKILYSAQNNQFLLSYLSFSRLIQFEGNEKQ---QGNLNYQSPEVIN-------KKKPYKITADIF
| |..||.. | ...... .. |.... . |. .   .   .|..||..|       |......  ||.
IKPQNILINNQ-GNYVYCDFGISKFLKNNQNQQCQYKGYTHYYYPPEQYNCPEQEHNKNQKINYKSDIY

Kinase 13481.AA TKL 153-198 17 2e-06 18.94 In-house 200-281 (364) Show / Hide
Range on Protein: 153-198
Range on HMM: 200-281/364
Sequence Identity: 17% (14 aa)

FSRLIQFEG---------------------NEKQQGNLNYQSPEVINKK---------------KPYKITADIFSIGVILLE
.|| .. .|                     . .| |.... .|||....               ..|   .|..| |..| |
LSRFMSQSGNMNDTMTTMMESAEHQNNRKTTMTQCGTPRWMAPEVLRGQMNYTEKVGIDEFCKGFEYSEKCDVYSFGIVLWE

Kinase 13481.AA ULK 153-196 22 2e-06 18.68 In-house 184-242 (324) Show / Hide
Range on Protein: 153-196
Range on HMM: 184-242/324
Sequence Identity: 22% (13 aa)

FSRLIQFEGNEKQQ-----------GNLNYQSPEVIN----KKKPYKITADIFSIGVIL
|.. .. .. |.|.           |   | .|....    .|..| . .||.|.|.|.
FAKHVDNNNMEQQMCQTCVNEKRIKGTPLYMAPQILQGQGEQKPYYDYKCDIWSLGCIF

Kinase 13481.AA MLK 164-196 31 2e-06 18.31 In-house 192-226 (291) Show / Hide
Range on Protein: 164-196
Range on HMM: 192-226/291
Sequence Identity: 31% (11 aa)

KQQGNLNYQSPEVI--NKKKPYKITADIFSIGVIL
...|.. . .||||   .  .| . .|..|.||.|
SNAGTYAWMAPEVIQQFRCEKYSEKCDVWSWGVVL

Kinase 13481.AA HH498 164-198 40 2e-06 15.85 In-house 184-218 (284) Show / Hide
Range on Protein: 164-198
Range on HMM: 184-218/284
Sequence Identity: 40% (14 aa)

KQQGNLNYQSPEVINKKKPYKITADIFSIGVILLE
|| ||| . .|||      | | .|.|| . .. |
KQPGNLRWMAPEVFSQCQKYSIKVDVFSYAMCIWE

Kinase 13481.AA Ciliate-A8 119-147 48 1.3e-05 16.21 In-house 123-151 (151) Show / Hide
Range on Protein: 119-147
Range on HMM: 123-151/151
Sequence Identity: 48% (14 aa)

LLLIQEKQKVLRYIEPEKILYSAQNNQFL
||. |||  ..  | |. |||| ..|||.
LLVFQEKGIIHCDIKPQNILYSWSKNQFI

Kinase 13481.AA Pkinase 169-203 40 0.000948 14.34 Pfam 175-209 (293) Show / Hide
Range on Protein: 169-203
Range on HMM: 175-209/293
Sequence Identity: 40% (14 aa)

LNYQSPEVINKKKPYKITADIFSIGVILLEALLQR
..| .||||.. ..|   .|..|.|.|| | |. |
PWYMAPEVIRGGQYYGPKVDMWSCGCILYEMLCGR

Kinase 13481.AA TKL 39-118 11 0.04078 3.43 In-house 1-122 (364) Show / Hide
Range on Protein: 39-118
Range on HMM: 1-122/364
Sequence Identity: 11% (14 aa)

ISRSSSSLVVQAKSLNHN-------NSNVAIKILNYKYNSKINS---------------------QKLSKQVDFLDNLKGE---KYVLQFIERIQDLNQG
| . ... | ..|  ...       .  ||.|... ..... ..                     ... ..  .  ...       ..||.   .. ..|
IGSGGFGEVYKGKWRGWGGKCPSDTGKDVAVKKFKSHNDDEFTKNSQENNDNNNYSDMQLNDPEASWFRFFEEEEIMMMSRLRHPNIVQFMGYCCCPPCG

I-----------TAIVTEYCER
             .||.|||..
CVCMHPVGPWGQLCIVMEYCPG

Kinase 13481.AA C8 37-74 18 0.296088 0.25 In-house 5-41 (226) Show / Hide
Range on Protein: 37-74
Range on HMM: 5-41/226
Sequence Identity: 18% (7 aa)

KQISRSSSSLVVQAKSLNHNNSNVAIKILNYKYNSKIN
. .|  . ..|..|| .. .| ....|.. .. ...|.
QYLSFGAYGMVLKAKNVK-DNREIVLKFQKCQNKQDIQ