Gene 1365 (Tetrahymena)

1365

Species: Tetrahymena
Alias: 133.m00090, 1122, 1365, PreTt01365, TTHERM_00790750
External Links: Tetrahymena Genome Database (TGD)
Annotation:

Classification

Group: Other
Family: Ciliate-E1

Sequence

Name Sequence Type Origin Length Description Download
1365.AA Protein None 2411 None Fasta, JSON
1365.kin_dom Protein Kinase Domain None 189 None Fasta, JSON
1365.NA RNA None 7236 None Fasta, JSON

Protein domain

Protein domains of 1365.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Kinase 1365.AA Ciliate-B2 375-563 41 1e-99 235.2 In-house 1-197 (197) Show / Hide 
Range on Protein: 375-563
Range on HMM: 1-197/197
Sequence Identity: 41% (83 aa)

YIITKYLRQGGEGILFLGKGLNAKNEYEDLVFKFIFE---YDTEELNEEIKIMRTFQKYINTIELHDYFFIEEFNVAILVLENCKYSLFDQLTKIHNKEN
|...||. .||.|. . |  ..   ||.||.||  |.    | ||...|||||  |...|| ... |.. |.| .. .|..| |..|| . | || .|. 
YYLCKYINKGGCGFICEGYKKHSIREYQDLAFKIYFNKQDCDKEEIQHEIKIMKMFEYNINVVKYIDHIQINE-TIDVLIMEKCECSLKQELQKI-QKQQ

IDLTFLNCIQLVLDLIDGLIQLRLYKVLHLDIKPANILVSQQDNYILADFGISQFKT--NQIKVKGFTQGYAPEELLNDE-----SLKVDYKSDIYSLG
.. .  . .|.. .|||||||.|.| .|||||||.|||..|..||.. |||||  |    |||.||||. ||. | ...      ....|..|||||.|
KCFNNQKLYQMIFQLIDGLIQFRMYNILHLDIKPQNILFMQNGNYVYCDFGISSIKKDNQQIKIKGFTKKYASPEQMECDHNQTFVTNIDFQSDIYSMG
Kinase 1365.AA Ciliate-E1 381-560 33 4.7e-59 190.56 In-house 1-202 (202) Show / Hide 
Range on Protein: 381-560
Range on HMM: 1-202/202
Sequence Identity: 33% (68 aa)

LRQGGEGILFLGKGLNAK-NEYEDLVFKFIFEYD----TEELNEEIKIMRTFQKYINTIELHDYFFIEEFNVAILVLENCKYSLFDQLT--------KIH
. .|...| | .|  | . |........ .| |.    ..|..|..|||  |.|....|.. ||..|.. .. |...|.|..||.|.|.        ...
IGNGSFSIVFKAKQQNNNYNQVAQKIINCCFNYNQNHFQDEIKEYYKIMK-FKKECYIIQIIDYIKIDQNYICIIIFECCCCSLKDYLQNHNRLEYWQQC

NKENIDLTFLNCIQLVLDLIDGLIQLRLYKVLHLDIKPANILVSQQDNYILADFGISQ----FKTNQIKVKGFTQGYAPEELLN------DESLKVDYKS
.......||....|.. .||||||.|. |...|.||||.|||...|.||...|||||.     ...|...||.|. |.|.| .|      ... |..|||
QQNQNQFTFQQKMQIIFQLIDGLIELHQYNIIHRDIKPQNILINNQGNYVYCDFGISKFLKNNQNQQCQYKGYTHYYYPPEQYNCPEQEHNKNQKINYKS

DIY
|||
DIY
Kinase 1365.AA TKL-Unique 468-563 25 8.9e-14 45.12 In-house 101-215 (290) Show / Hide 
Range on Protein: 468-563
Range on HMM: 101-215/290
Sequence Identity: 25% (30 aa)

NKENIDLTFLNCIQLVLDLIDGLIQLRLYK--VLHLDIKPANILVSQQ-----DNYILADFGISQFKT--NQIKVK-----------GFTQGYAPEELLN
|..|..|.... .....|  .|.. |  ..  ..|.|.|. |.||..       |  ..|||.| |..  |. ...           | ..  |||.| .
NNNNCKLNMQQRVKMAIDIAQGMYYLHHCEPPIIHRDLKSSNFLVDNNSNIAEWNIKICDFGLSKFNSKINKMTNNEHKGTRNQTRCGSFRWMAPEVLRM

DESLKVDYKSDIYSLG
 .  . . |||.|| |
NF-CQYSEKSDVYSFG
Kinase 1365.AA S_TKc 375-612 18 4.2e-12 0.61 SMART 1-231 (231) Show / Hide 
Range on Protein: 375-612
Range on HMM: 1-231/231
Sequence Identity: 18% (47 aa)

YIITKYLRQGGEGILFLGKGLNAKNEYEDLVFKFIFEYDTEELNEEIKIMRTFQKYINTIELHDYFFIEEFNVAILVLENCKY---SLFDQLTKIHN-KE
| | . . .|. |  ....  .     .    | |     | .  ||.|..   .  | . |.|.|     .   .|.| |     .||| . |    . 
YEILRKIGKGAFGKVYKCRHKK---TGRIVAIKIIK----EHIRREIQILKK--HHPNIVKLYDVFQD---DHLYMVMEYCDGDLGDLFDYIKKRGRHGL

NIDLTFLNCIQLVLDLIDGLIQLRLYKVLHLDIKPANILVSQQDNYILADFGISQFKTNQIKVKGFTQGYAPEELLNDESLKVDY-KSDIYSLG------
.  ..   .  ..  ....|  .   ...| |.||.|||...  .  ..|||.. .     .    |  | . |.|     . .. |.|..|.|      
RFPFPE-HARFYMYQICCALEYCHSHGIIHRDLKPENILLDE--HIKICDFGLARQL----TTFCGTPWYMAPEVL-----GYGKCKCDWWSCGCILYEM

----RTFEKIIQLLKNFNKYEKQIQIIDKLVKFMVLNSIGKRFDCLSLHE--------QFI
      |.   |. . |.|     . .| ... .      ||  .  . .        ...
LCGYPPFP---QMQMMFKKIG-SPEAKD-FIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF
Kinase 1365.AA TKL 497-563 17 7.4e-12 38.99 In-house 160-276 (364) Show / Hide 
Range on Protein: 497-563
Range on HMM: 160-276/364
Sequence Identity: 17% (20 aa)

KVLHLDIKPANILVSQQDN--------------YILADFGISQFKTNQI----------------------KVKGFTQGYAPEELLNDE-----------
...| |.|..|||| .  .                ..|||.|.|...                          .. | .. . |.|...           
PIIHRDLKSKNILVDENWTNVSNYMYNPNADWCCKICDFGLSRFMSQSGNMNDTMTTMMESAEHQNNRKTTMTQCGTPRWMAPEVLRGQMNYTEKVGIDE

---SLKVDYKSDIYSLG
   ... . |.|.|| |
FCKGFEYSEKCDVYSFG
Kinase 1365.AA Ciliate-E2 375-563 19 3.5e-11 34.63 In-house 1-283 (365) Show / Hide 
Range on Protein: 375-563
Range on HMM: 1-283/365
Sequence Identity: 19% (55 aa)

YIITKYLRQGGEGILFLGKGLNAKNEY--------------------EDLVFKFIFEYDTEELNEEIKIMRTFQ---------------KYINTIELHDY
|.. | . ||. |. ...|  . ....                         | . ... |... ||.|||. .               .  | |.....
YKFIKKIGQGNFGSVYKCKVWKVQKQFAIKIIDQKQQRQQMQEKVKIKIYAMKIMKKNQIEQIKQEIHIMREINCFYKKINEKNILEQLNHPNIIKMYEC

FFIEEFNVAILVLENCKY-SLFD--QLTKIHNKENID----LTFLNCIQLVLDLID---------------GLIQLRLYK-VLHLDIKPANILVSQQDNY
|  .  |   ||.| |.. .|||  .  |.  ...|.    .|   ....   ...               .|  |   . ..| |||| |||.      
FQEKDDNNIYLVMEYCQGGDLFDYIKNNKKKRNHEIEKDKYFTEKEIKYIMKQILQGFKTKAEFYIACIILALEYLHSKNNIIHRDIKPENILF-----I

ILADFGISQFKTNQ-----------IKVKGF------------------------TQGYAPEELLNDESLK-------VDYKSDIYSLG
 ..|||.|.. ...           ..   .                        | || . | || ..          |||.||.|||
KIIDFGLSKKYDDDNQNRTHKQQCKWYMF-KNDTSRTPGYMDQIIQQNMFNTICGTPGYMAPEILNGKKYDNQQKQKGYDYKCDIWSLG
Kinase 1365.AA Ciliate-E2-Unclassified 375-563 18 5.6e-11 34.35 In-house 1-257 (352) Show / Hide 
Range on Protein: 375-563
Range on HMM: 1-257/352
Sequence Identity: 18% (48 aa)

YIITKYLRQGGEGILFLGKGLNAKNEY--------EDLVFKFIFEY-DTEELNEEIKIMRTFQKYINT----------------IELHDYFFIEEFNVAI
|.| | . ||| |. .. .  . | .|           . . . .. | |..||.. ...    |..                 . .....  .  .  .
YKIIKQIGQGGFGKVYKCQHKKQK-QYYAMKYMKKIQIYKQKQIMNKD-EIMNEMKEMNNKKK-YHQRKYNKIMQQILLNHPHPFIVKMFYCFQDKQNIY

LVLENCKYSLFDQLTKI-------------HNKENIDLTFLNCI-----QLVLDLIDGLIQLRLYK-VLHLDIKPANILVSQQD---NYILADFGISQFK
.|.| |..    |  |.             ..|..  .|  ...     ..   ...|| .|   . ..| |||| |||....    .  ..||||| . 
IVMEYCEGGDLWQYIKKRKKQKQKGNDLFHNMKQRKIFTEQQAKYKKAKFYFAQILQGLEYLHHKNNIIHRDIKPENILFDNNGKNYYIKIIDFGISKKY

TNQIKVK------------------GFTQGYA----PEELLNDESLKVD--YKSDIYSLG
 .... .                    | .|     . |.|  .       ||.||.|||
QQNNNCDTNQQQKMQIWKQQMMWTFCGTPNYMPQYTAPEVLQGQNYDHSKAYKCDIWSLG
Kinase 1365.AA Ciliate-E5 407-527 28 2.1e-10 29.83 In-house 33-154 (271) Show / Hide 
Range on Protein: 407-527
Range on HMM: 33-154/271
Sequence Identity: 28% (36 aa)

KFIFEYDTEELNEEIKIMRTFQ-KYINTIELHDYFFIE--EFNVAILVLENCKYSLFDQLTKIHNKENIDLTFLNCIQLVLDLIDGLIQLRLYKVLHLDI
|..   . | .  | .|.  |. ..|  |.  ...  .  . |  ... | ||. |  .| ||  .    .  ..  |. |.|. || ..    ..||||
KCKNQKQCEDNQREFNILKQFNSPHI--IKVYQIYQYQYENMNYQFIIMERCKCDLHTYLNKIIYQMK-WQKHQDIYQICLQLVKGLQDIHQKNIIHLDI

KPANILVSQQDNYILADFGIS-QFK
|||||| .       .|.||| .||
KPANILLGYDNKWKYIDMGISRKFK
Kinase 1365.AA Ciliate-E3 480-570 30 2.5e-10 28.71 In-house 106-202 (202) Show / Hide 
Range on Protein: 480-570
Range on HMM: 106-202/202
Sequence Identity: 30% (30 aa)

IQLVLDLIDGLIQLRLYKVLHLDIKPANILVSQQDN---YILADFGIS-QFKTNQ--IKVK--GFTQGYAPEELLNDESLKVDYKSDIYSLGRTFEKII
....  .| |.| .   .. | |||| ||||..  |      .||| | | . |   .  .  |.|  ||. |..   . .    ||.||.|  |  ..
YDICIQIIQGMIAIHEKNIIHSDIKPDNILVDKNNNQLIIKICDFGESKQLRKNKGHTHTQYQGWTPFYAAPEQNDQQQISKE--SDYYSVGAVFCQLC
Kinase 1365.AA WEE 499-566 24 1.2e-09 28.59 In-house 134-226 (297) Show / Hide 
Range on Protein: 499-566
Range on HMM: 134-226/297
Sequence Identity: 24% (23 aa)

LHLDIKPANILVSQQD--------------------NYILADFGISQFKT-NQIKVKGF---TQGYAPEELLND-ESLKVDYKSDIYSLGRTF
.|.||||.||..| ..                    .. ..||| .   . |  ...      . | . |.|..  .   .||.||.||| |.
VHMDIKPENIFISKKMNCNQIVNNDQQNNNDWWFNMMCKIGDFGHVTDMNSNNNNPHQEQEGDSRYMAPEILQGYYHYTHLYKADIFSLGITI
Kinase 1365.AA C8 379-566 20 1.9e-09 29.05 In-house 5-226 (226) Show / Hide 
Range on Protein: 379-566
Range on HMM: 5-226/226
Sequence Identity: 20% (46 aa)

KYLRQGGEGILFLGKGLNAKNEYEDLVFKFIFEYDTEELNEEIKIMRTFQKYINTIELHDYFFIE----EFNVAILVLENCK-----------YSLFD--
.|| .|. |.   .|  |.| .  . | ||    .... .....||. . .    ... | . .|    .       .|.|.           ... .  
QYLSFGAYGMVLKAK--NVK-DNREIVLKFQKCQNKQDIQNIESIMKEY-EMPQVFQQYDFYVNEYDCFYEMYEVFEEEKCSNEKIVQTEEKSCFVMEME

-------QLTKIHNKENIDLTFLNCIQLVLDLIDGLIQLRLYKVLHLDIKPANILVSQQDNYI----LADFGIS-QFKTNQ--IKVKGF----TQGYAPE
       || .   ...  ..  .  .. . .|||.  . . ...| |||| |.||  . ||.    |.|||.. | . |.  |  | .    |..|   
LCEQNLKQLYDERRNKQQQFSKEMKEIIAIQMIDGVNYIHCKNIMHRDIKPHNFLVCLDQNYGFEIKLCDFGFASQVSKNKSHIQSKKMNTCGTWAYFAP

ELLND---ESLKVDYKSDIYSLGRTF
| ...   .  .   .||..|.|   
EIEKKQDNQYKQYRIQSDLFSVGLVL
Kinase 1365.AA Pkinase 497-563 26 2.3e-07 27.12 Pfam 128-199 (293) Show / Hide 
Range on Protein: 497-563
Range on HMM: 128-199/293
Sequence Identity: 26% (20 aa)

KVLHLDIKPANILVSQQDNYI-----LADFGISQF--KTNQIKVKGF--TQGYAPEELLNDESLKVDYKSDIYSLG
...| |.||.|||.. ....|     ..|||.. .    |.   ..|  | .|.. |... .. . ..|.|..|.|
GIIHRDLKPENILID-NNGHIDACVKICDFGLAKQFDY-NNS-MTTFCGTPWYMAPEVIR-GGQYYGPKVDMWSCG
Kinase 1365.AA TyrKc 375-611 17 3.2e-05 -138.13 SMART 1-280 (280) Show / Hide 
Range on Protein: 375-611
Range on HMM: 1-280/280
Sequence Identity: 17% (50 aa)

YIITKYLRQGGEGILFLGKGLNAKNEYEDLVFKFIFEYDTEELNEEIKIMRTF-QKYINTIELHDYFFIE-----EFNVAILVLENCKY-SLFDQLTKIH
    | |  |  |. ..|.        ..   | . |.  |.. .|..||. .  .  | . |. .   .     .     .|.| ... .| | | | .
ITLGKKLGEGAFGEVYKGTWK------IQVAVKMLKEDAREDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPHGDLKDYLRKHR

NKENIDLTFLNCIQLVLDLIDGLIQLRLYKVLHLDIKPANILVSQQDNYILADFGISQFKTNQ--------IKVKGF---TQG------YAPEELLNDES
.|    |.    ..  ..  .|   |   .. | |.   |.||. .     .||| | . ..          ..|     . .      .||| .     
PK----LCMKDLLSFCWQIACGMEYLHSKNCIHRDLAARNCLVGENHTVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGKTMLPIRWMAPECI---NY

LKVDYKSDIYS----------------LG-----RTFEKIIQLLKNFNKYEKQIQ--------IIDKLVKFMVL---NSIGKRFDCLSLHEQF
 |   |||..|                 |      . . .|...|. .  ..             |.. . |         .|     .||.|
GKFTTKSDVWSFGVCMWEIFTYGQQPYPGMIQQMMSNQEVIEYVKQGYRMPQPPNDYPMSFVCCPDEMYQIMKQCWHEDPEDRPTFSEIHECF
TPR_2 1365.AA TPR_2 675-708 26 0.00648 14.4 Pfam 1-34 (34) Show / Hide 
Range on Protein: 675-708
Range on HMM: 1-34/34
Sequence Identity: 26% (9 aa)

AYFIYQQGLQKLNQGVYQQALQNFQESLAIFKQN
|.  |..|.  ..|| |..|.. ....|... .|
AEAWYNLGQCYYKQGDYDEAIEYYEKALKLDPNN
TPR 1365.AA TPR 675-708 26 0.011678 16.08 SMART 1-34 (34) Show / Hide 
Range on Protein: 675-708
Range on HMM: 1-34/34
Sequence Identity: 26% (9 aa)

AYFIYQQGLQKLNQGVYQQALQNFQESLAIFKQN
|   |..|.  ...| |..|.. .|..|..  .|
AEAWYNLGNCYYKMGDYDEAIECYQKALELDPNN
TPR_1 1365.AA TPR_1 675-708 26 0.107085 9.91 Pfam 1-34 (34) Show / Hide 
Range on Protein: 675-708
Range on HMM: 1-34/34
Sequence Identity: 26% (9 aa)

AYFIYQQGLQKLNQGVYQQALQNFQESLAIFKQN
|   |. |.  ...| |..|.. .|. |..  .|
AEAWYNLGNCYYKMGNYDEAIECYQKALELNPNN
TPR 1365.AA TPR 717-750 26 0.054934 11.66 SMART 1-34 (34) Show / Hide 
Range on Protein: 717-750
Range on HMM: 1-34/34
Sequence Identity: 26% (9 aa)

AECLDKIGICYYNLVQYQIAYSYHNEAIRMLKKI
||..  .| |||.. .|. |  . ..|...  . 
AEAWYNLGNCYYKMGDYDEAIECYQKALELDPNN
TPR_2 1365.AA TPR_2 717-750 29 0.33217 8.35 Pfam 1-34 (34) Show / Hide 
Range on Protein: 717-750
Range on HMM: 1-34/34
Sequence Identity: 29% (10 aa)

AECLDKIGICYYNLVQYQIAYSYHNEAIRMLKKI
||..  .| |||.. .|. |  | ..|..   . 
AEAWYNLGQCYYKQGDYDEAIEYYEKALKLDPNN
TPR_1 1365.AA TPR_1 717-750 26 1.938174 5.52 Pfam 1-34 (34) Show / Hide 
Range on Protein: 717-750
Range on HMM: 1-34/34
Sequence Identity: 26% (9 aa)

AECLDKIGICYYNLVQYQIAYSYHNEAIRMLKKI
|| .  .| |||.. .|. |  . ..|...  . 
AEAWYNLGNCYYKMGNYDEAIECYQKALELNPNN
TPR 1365.AA TPR 839-872 26 0.00148 19.06 SMART 1-34 (34) Show / Hide 
Range on Protein: 839-872
Range on HMM: 1-34/34
Sequence Identity: 26% (9 aa)

AEFQQSLALCYLKQSDYKTSLKYFTESHKILDNI
||    |..||.|. ||.  ....... ..  | 
AEAWYNLGNCYYKMGDYDEAIECYQKALELDPNN
TPR_2 1365.AA TPR_2 839-872 35 0.002333 15.97 Pfam 1-34 (34) Show / Hide 
Range on Protein: 839-872
Range on HMM: 1-34/34
Sequence Identity: 35% (12 aa)

AEFQQSLALCYLKQSDYKTSLKYFTESHKILDNI
||    |..||.|| ||.  ..|. .. |.  | 
AEAWYNLGQCYYKQGDYDEAIEYYEKALKLDPNN
TPR_1 1365.AA TPR_1 839-872 23 0.004226 14.81 Pfam 1-34 (34) Show / Hide 
Range on Protein: 839-872
Range on HMM: 1-34/34
Sequence Identity: 23% (8 aa)

AEFQQSLALCYLKQSDYKTSLKYFTESHKILDNI
||    |..||.|. .|.  .... .  ..  | 
AEAWYNLGNCYYKMGNYDEAIECYQKALELNPNN
TPR 1365.AA TPR 882-915 20 0.001772 18.8 SMART 1-34 (34) Show / Hide 
Range on Protein: 882-915
Range on HMM: 1-34/34
Sequence Identity: 20% (7 aa)

GQSHNNIGVVYFYQANYEESLLQISKSLQIFKSL
 . ..|.|..|. . .|.| .   .|.|..  . 
AEAWYNLGNCYYKMGDYDEAIECYQKALELDPNN
TPR_1 1365.AA TPR_1 882-915 23 0.007069 14.03 Pfam 1-34 (34) Show / Hide 
Range on Protein: 882-915
Range on HMM: 1-34/34
Sequence Identity: 23% (8 aa)

GQSHNNIGVVYFYQANYEESLLQISKSLQIFKSL
 . ..|.|..|. . ||.| .    | |..  . 
AEAWYNLGNCYYKMGNYDEAIECYQKALELNPNN
TPR_2 1365.AA TPR_2 882-915 23 0.012261 13.42 Pfam 1-34 (34) Show / Hide 
Range on Protein: 882-915
Range on HMM: 1-34/34
Sequence Identity: 23% (8 aa)

GQSHNNIGVVYFYQANYEESLLQISKSLQIFKSL
   ..|.|..|..| .|.| .    |.|...   
AEAWYNLGQCYYKQGDYDEAIEYYEKALKLDPNN
TPR 1365.AA TPR 924-957 17 0.000452 20.77 SMART 1-34 (34) Show / Hide 
Range on Protein: 924-957
Range on HMM: 1-34/34
Sequence Identity: 17% (6 aa)

AYSFNNLAMIYAQKGKYQDSKDNFLESIQILNKQ
|  ..||...| ..|.|..  . . .....  . 
AEAWYNLGNCYYKMGDYDEAIECYQKALELDPNN
TPR_2 1365.AA TPR_2 924-957 17 0.000647 17.94 Pfam 1-34 (34) Show / Hide 
Range on Protein: 924-957
Range on HMM: 1-34/34
Sequence Identity: 17% (6 aa)

AYSFNNLAMIYAQKGKYQDSKDNFLESIQILNKQ
|.  .||...|...|.|.. .. . .....  . 
AEAWYNLGQCYYKQGDYDEAIEYYEKALKLDPNN
TPR_1 1365.AA TPR_1 924-957 17 0.000717 17.5 Pfam 1-34 (34) Show / Hide 
Range on Protein: 924-957
Range on HMM: 1-34/34
Sequence Identity: 17% (6 aa)

AYSFNNLAMIYAQKGKYQDSKDNFLESIQILNKQ
|  ..||...| ..|.|..  . . . ...  . 
AEAWYNLGNCYYKMGNYDEAIECYQKALELNPNN
TPR_2 1365.AA TPR_2 963-996 11 25.966307 1.65 Pfam 1-34 (34) Show / Hide 
Range on Protein: 963-996
Range on HMM: 1-34/34
Sequence Identity: 11% (4 aa)

VQNLQNVGYHFLNLRNPEKSFYFFLKSLEILSKT
.  . | |   ........   .. |.|..  . 
AEAWYNLGQCYYKQGDYDEAIEYYEKALKLDPNN
TPR_1 1365.AA TPR_1 1619-1652 23 0.000111 20.33 Pfam 1-34 (34) Show / Hide 
Range on Protein: 1619-1652
Range on HMM: 1-34/34
Sequence Identity: 23% (8 aa)

ASLYNNIGITYFHLENYKISLKYHQQSVEMKKQI
|  ..|.| .|....||.  ... |. .|.  . 
AEAWYNLGNCYYKMGNYDEAIECYQKALELNPNN
TPR 1365.AA TPR 1619-1652 20 0.000135 22.52 SMART 1-34 (34) Show / Hide 
Range on Protein: 1619-1652
Range on HMM: 1-34/34
Sequence Identity: 20% (7 aa)

ASLYNNIGITYFHLENYKISLKYHQQSVEMKKQI
|  ..|.|  |.....|.  ... |...|.  . 
AEAWYNLGNCYYKMGDYDEAIECYQKALELDPNN
TPR_2 1365.AA TPR_2 1619-1652 17 0.005652 14.61 Pfam 1-34 (34) Show / Hide 
Range on Protein: 1619-1652
Range on HMM: 1-34/34
Sequence Identity: 17% (6 aa)

ASLYNNIGITYFHLENYKISLKYHQQSVEMKKQI
| ...|.|  |.....|.  ..| .....   . 
AEAWYNLGQCYYKQGDYDEAIEYYEKALKLDPNN
TPR 1365.AA TPR 1661-1694 23 0.01323 15.9 SMART 1-34 (34) Show / Hide 
Range on Protein: 1661-1694
Range on HMM: 1-34/34
Sequence Identity: 23% (8 aa)

ALSLSHIACCYQRLYDYPNSLKCHQESIEMNTRI
|  .. .. || .. ||   ..| |...|..   
AEAWYNLGNCYYKMGDYDEAIECYQKALELDPNN
TPR_2 1365.AA TPR_2 1661-1694 14 0.221892 8.97 Pfam 1-34 (34) Show / Hide 
Range on Protein: 1661-1694
Range on HMM: 1-34/34
Sequence Identity: 14% (5 aa)

ALSLSHIACCYQRLYDYPNSLKCHQESIEMNTRI
|  .  ...|| .. ||   ... ..... . . 
AEAWYNLGQCYYKQGDYDEAIEYYEKALKLDPNN
TPR_1 1365.AA TPR_1 1661-1691 25 0.454085 7.72 Pfam 1-31 (34) Show / Hide 
Range on Protein: 1661-1691
Range on HMM: 1-31/34
Sequence Identity: 25% (8 aa)

ALSLSHIACCYQRLYDYPNSLKCHQESIEMN
|  .. .. || .. .|   ..| |. .|.|
AEAWYNLGNCYYKMGNYDEAIECYQKALELN
TPR_1 1365.AA TPR_1 1703-1726 33 0.018278 12.59 Pfam 1-24 (34) Show / Hide 
Range on Protein: 1703-1726
Range on HMM: 1-24/34
Sequence Identity: 33% (8 aa)

AYSHNNLGSFYRQIGDFESSIKSY
|  ..|||  |.. |...  |. |
AEAWYNLGNCYYKMGNYDEAIECY
TPR 1365.AA TPR 1703-1736 26 0.186272 7.0 SMART 1-34 (34) Show / Hide 
Range on Protein: 1703-1736
Range on HMM: 1-34/34
Sequence Identity: 26% (9 aa)

AYSHNNLGSFYRQIGDFESSIKSYSSCQNEIFKI
|  ..|||  |.. ||..  |. |. .     . 
AEAWYNLGNCYYKMGDYDEAIECYQKALELDPNN
TPR_2 1365.AA TPR_2 1703-1726 37 0.223341 8.96 Pfam 1-24 (34) Show / Hide 
Range on Protein: 1703-1726
Range on HMM: 1-24/34
Sequence Identity: 37% (9 aa)

AYSHNNLGSFYRQIGDFESSIKSY
|. ..|||  |.. ||..  |. |
AEAWYNLGQCYYKQGDYDEAIEYY
TPR 1365.AA TPR 1746-1779 23 0.004304 17.52 SMART 1-34 (34) Show / Hide 
Range on Protein: 1746-1779
Range on HMM: 1-34/34
Sequence Identity: 23% (8 aa)

PNCLNNLAICFFSMGNLKRAFKIFQDSIAMQLNQ
. ...||. |...||... | . .| ..... | 
AEAWYNLGNCYYKMGDYDEAIECYQKALELDPNN
TPR_1 1365.AA TPR_1 1746-1779 26 0.006885 14.07 Pfam 1-34 (34) Show / Hide 
Range on Protein: 1746-1779
Range on HMM: 1-34/34
Sequence Identity: 26% (9 aa)

PNCLNNLAICFFSMGNLKRAFKIFQDSIAMQLNQ
.. ..||. |...|||.. | . .|  .... | 
AEAWYNLGNCYYKMGNYDEAIECYQKALELNPNN
TPR_2 1365.AA TPR_2 1746-1779 17 0.051989 11.2 Pfam 1-34 (34) Show / Hide 
Range on Protein: 1746-1779
Range on HMM: 1-34/34
Sequence Identity: 17% (6 aa)

PNCLNNLAICFFSMGNLKRAFKIFQDSIAMQLNQ
. ...||. | . .|....| . .. ...   | 
AEAWYNLGQCYYKQGDYDEAIEYYEKALKLDPNN
TPR_2 1365.AA TPR_2 1788-1821 23 0.003424 15.38 Pfam 1-34 (34) Show / Hide 
Range on Protein: 1788-1821
Range on HMM: 1-34/34
Sequence Identity: 23% (8 aa)

AFTINQIGLLYLKSRSYKKALSYLLESLNIAKKC
|   ...|..|.| . |..|. |. ..| .. ..
AEAWYNLGQCYYKQGDYDEAIEYYEKALKLDPNN
TPR 1365.AA TPR 1788-1821 20 0.00519 17.25 SMART 1-34 (34) Show / Hide 
Range on Protein: 1788-1821
Range on HMM: 1-34/34
Sequence Identity: 20% (7 aa)

AFTINQIGLLYLKSRSYKKALSYLLESLNIAKKC
| . ...|..|.|   |..|. .. ..| .. ..
AEAWYNLGNCYYKMGDYDEAIECYQKALELDPNN
TPR_1 1365.AA TPR_1 1788-1821 20 0.024758 12.13 Pfam 1-34 (34) Show / Hide 
Range on Protein: 1788-1821
Range on HMM: 1-34/34
Sequence Identity: 20% (7 aa)

AFTINQIGLLYLKSRSYKKALSYLLESLNIAKKC
| . ...|..|.|   |..|. .. . | .  ..
AEAWYNLGNCYYKMGNYDEAIECYQKALELNPNN
TPR_1 1365.AA TPR_1 1830-1863 32 1.5e-07 30.3 Pfam 1-34 (34) Show / Hide 
Range on Protein: 1830-1863
Range on HMM: 1-34/34
Sequence Identity: 32% (11 aa)

ANYFNNIGLCYLKLSNYEKALKYINQSHELRKQI
|. ..|.|.||.|. ||..|... ..  ||. . 
AEAWYNLGNCYYKMGNYDEAIECYQKALELNPNN
TPR 1365.AA TPR 1830-1863 29 4.7e-07 30.69 SMART 1-34 (34) Show / Hide 
Range on Protein: 1830-1863
Range on HMM: 1-34/34
Sequence Identity: 29% (10 aa)

ANYFNNIGLCYLKLSNYEKALKYINQSHELRKQI
| ...|.|.||.|. .|..|... ... ||  . 
AEAWYNLGNCYYKMGDYDEAIECYQKALELDPNN
TPR_2 1365.AA TPR_2 1830-1863 29 1.8e-05 23.43 Pfam 1-34 (34) Show / Hide 
Range on Protein: 1830-1863
Range on HMM: 1-34/34
Sequence Identity: 29% (10 aa)

ANYFNNIGLCYLKLSNYEKALKYINQSHELRKQI
| . .|.|.||.|. .|..|..| ... .|  . 
AEAWYNLGQCYYKQGDYDEAIEYYEKALKLDPNN
TPR 1365.AA TPR 1872-1905 11 0.023813 14.85 SMART 1-34 (34) Show / Hide 
Range on Protein: 1872-1905
Range on HMM: 1-34/34
Sequence Identity: 11% (4 aa)

LDSLNSLGLFYSDLNEKNLALKYFDQLIQNREKL
 . .. ||. |  ... . |...... ..  .. 
AEAWYNLGNCYYKMGDYDEAIECYQKALELDPNN
TPR_1 1365.AA TPR_1 1872-1905 11 0.03466 11.62 Pfam 1-34 (34) Show / Hide 
Range on Protein: 1872-1905
Range on HMM: 1-34/34
Sequence Identity: 11% (4 aa)

LDSLNSLGLFYSDLNEKNLALKYFDQLIQNREKL
 . .. ||. |  ... . |...... .. ... 
AEAWYNLGNCYYKMGNYDEAIECYQKALELNPNN
TPR_2 1365.AA TPR_2 1872-1905 14 0.264513 8.7 Pfam 1-34 (34) Show / Hide 
Range on Protein: 1872-1905
Range on HMM: 1-34/34
Sequence Identity: 14% (5 aa)

LDSLNSLGLFYSDLNEKNLALKYFDQLIQNREKL
 . .. ||. |  ...   |..|......  .. 
AEAWYNLGQCYYKQGDYDEAIEYYEKALKLDPNN
TPR_1 1365.AA TPR_1 1914-1939 42 0.001341 16.55 Pfam 1-26 (34) Show / Hide 
Range on Protein: 1914-1939
Range on HMM: 1-26/34
Sequence Identity: 42% (11 aa)

ANLLNNIGCYLLKCGNTKQAIEYLQK
|. ..|.|  ..| || ..|||..||
AEAWYNLGNCYYKMGNYDEAIECYQK
TPR_2 1365.AA TPR_2 1914-1942 34 0.00419 15.07 Pfam 1-29 (34) Show / Hide 
Range on Protein: 1914-1942
Range on HMM: 1-29/34
Sequence Identity: 34% (10 aa)

ANLLNNIGCYLLKCGNTKQAIEYLQKSYQ
| ...|.|. ..| |. ..||||..|. .
AEAWYNLGQCYYKQGDYDEAIEYYEKALK
TPR 1365.AA TPR 1914-1947 29 0.00455 17.44 SMART 1-34 (34) Show / Hide 
Range on Protein: 1914-1947
Range on HMM: 1-34/34
Sequence Identity: 29% (10 aa)

ANLLNNIGCYLLKCGNTKQAIEYLQKSYQKRKFV
|  ..|.|  ..| |. ..|||..||. .     
AEAWYNLGNCYYKMGDYDEAIECYQKALELDPNN
TPR_1 1365.AA TPR_1 1956-1989 20 6.7e-05 21.1 Pfam 1-34 (34) Show / Hide 
Range on Protein: 1956-1989
Range on HMM: 1-34/34
Sequence Identity: 20% (7 aa)

AESANNIGVCYQYLNDKEKSIQYLNQSHSIFQKY
||  .|.|.||  ... .. |.....  ..  ..
AEAWYNLGNCYYKMGNYDEAIECYQKALELNPNN
TPR 1365.AA TPR 1956-1989 23 0.000298 21.37 SMART 1-34 (34) Show / Hide 
Range on Protein: 1956-1989
Range on HMM: 1-34/34
Sequence Identity: 23% (8 aa)

AESANNIGVCYQYLNDKEKSIQYLNQSHSIFQKY
||  .|.|.||  ..| .. |...... ..  ..
AEAWYNLGNCYYKMGDYDEAIECYQKALELDPNN
TPR_2 1365.AA TPR_2 1956-1989 26 0.000829 17.56 Pfam 1-34 (34) Show / Hide 
Range on Protein: 1956-1989
Range on HMM: 1-34/34
Sequence Identity: 26% (9 aa)

AESANNIGVCYQYLNDKEKSIQYLNQSHSIFQKY
||  .|.|.|| ...| .. |.|.... ... ..
AEAWYNLGQCYYKQGDYDEAIEYYEKALKLDPNN
TPR_1 1365.AA TPR_1 1998-2031 32 0.000476 18.12 Pfam 1-34 (34) Show / Hide 
Range on Protein: 1998-2031
Range on HMM: 1-34/34
Sequence Identity: 32% (11 aa)

ATSLSNLGQHYQEFGDYQKAQEYLTSSLNLRQKY
|  ..|||. | . |.|..| |..   | |. ..
AEAWYNLGNCYYKMGNYDEAIECYQKALELNPNN
TPR 1365.AA TPR 1998-2031 35 0.001076 19.52 SMART 1-34 (34) Show / Hide 
Range on Protein: 1998-2031
Range on HMM: 1-34/34
Sequence Identity: 35% (12 aa)

ATSLSNLGQHYQEFGDYQKAQEYLTSSLNLRQKY
|  ..|||. |   |||..| |... .| |  ..
AEAWYNLGNCYYKMGDYDEAIECYQKALELDPNN
TPR_2 1365.AA TPR_2 1998-2031 41 0.004414 14.99 Pfam 1-34 (34) Show / Hide 
Range on Protein: 1998-2031
Range on HMM: 1-34/34
Sequence Identity: 41% (14 aa)

ATSLSNLGQHYQEFGDYQKAQEYLTSSLNLRQKY
|  . |||| | . |||..| ||.  .| |  ..
AEAWYNLGQCYYKQGDYDEAIEYYEKALKLDPNN
TPR_2 1365.AA TPR_2 2040-2073 29 0.004082 15.11 Pfam 1-34 (34) Show / Hide 
Range on Protein: 2040-2073
Range on HMM: 1-34/34
Sequence Identity: 29% (10 aa)

SFALNRLAFCHYEFQNYKEALKSFNVVLSLQTNQ
  |...|. |.|. ..|.||.. .. .|.|  | 
AEAWYNLGQCYYKQGDYDEAIEYYEKALKLDPNN
TPR_1 1365.AA TPR_1 2040-2073 32 0.008731 13.71 Pfam 1-34 (34) Show / Hide 
Range on Protein: 2040-2073
Range on HMM: 1-34/34
Sequence Identity: 32% (11 aa)

SFALNRLAFCHYEFQNYKEALKSFNVVLSLQTNQ
. |...|. |.|. .||.||.. .. .|.|. | 
AEAWYNLGNCYYKMGNYDEAIECYQKALELNPNN
TPR 1365.AA TPR 2040-2073 29 0.011125 16.15 SMART 1-34 (34) Show / Hide 
Range on Protein: 2040-2073
Range on HMM: 1-34/34
Sequence Identity: 29% (10 aa)

SFALNRLAFCHYEFQNYKEALKSFNVVLSLQTNQ
. |...|. |.|   .|.||.. .. .|.|. | 
AEAWYNLGNCYYKMGDYDEAIECYQKALELDPNN
TPR_1 1365.AA TPR_1 2079-2112 20 0.000658 17.63 Pfam 1-34 (34) Show / Hide 
Range on Protein: 2079-2112
Range on HMM: 1-34/34
Sequence Identity: 20% (7 aa)

FNTQIHVGLCFQELGSYQEALKYFNQSLKILQRQ
 ..    |.|. ..| |.||...... |..    
AEAWYNLGNCYYKMGNYDEAIECYQKALELNPNN
TPR 1365.AA TPR 2079-2112 20 0.001194 19.37 SMART 1-34 (34) Show / Hide 
Range on Protein: 2079-2112
Range on HMM: 1-34/34
Sequence Identity: 20% (7 aa)

FNTQIHVGLCFQELGSYQEALKYFNQSLKILQRQ
  .    |.|.  .| |.||.......|..    
AEAWYNLGNCYYKMGDYDEAIECYQKALELDPNN
TPR_2 1365.AA TPR_2 2079-2112 26 0.001931 16.26 Pfam 1-34 (34) Show / Hide 
Range on Protein: 2079-2112
Range on HMM: 1-34/34
Sequence Identity: 26% (9 aa)

FNTQIHVGLCFQELGSYQEALKYFNQSLKILQRQ
.      |.|  ..| |.||..|....||.  . 
AEAWYNLGQCYYKQGDYDEAIEYYEKALKLDPNN
TPR_2 1365.AA TPR_2 2121-2143 21 12.616873 2.76 Pfam 12-34 (34) Show / Hide 
Range on Protein: 2121-2143
Range on HMM: 12-34/34
Sequence Identity: 21% (5 aa)

ADLGNQNQAIKQLNKVINILKQN
. .|.  .||. ..|.. .  .|
YKQGDYDEAIEYYEKALKLDPNN
TPR_1 1365.AA TPR_1 2123-2143 28 41.577322 0.87 Pfam 14-34 (34) Show / Hide 
Range on Protein: 2123-2143
Range on HMM: 14-34/34
Sequence Identity: 28% (6 aa)

LGNQNQAIKQLNKVINILKQN
.|| ..||. ..|.. .  .|
MGNYDEAIECYQKALELNPNN
TPR 1365.AA TPR 2152-2185 26 0.116534 8.79 SMART 1-34 (34) Show / Hide 
Range on Protein: 2152-2185
Range on HMM: 1-34/34
Sequence Identity: 26% (9 aa)

IHSLYNLGICFLKLGDTQNAYRIFKLFTDMQQQI
.  .|||| |..|.|| . |   ..   ... . 
AEAWYNLGNCYYKMGDYDEAIECYQKALELDPNN
Kinase 1365.AA Ciliate-E5 2156-2166 63 0.184145 0.28 In-house 261-271 (271) Show / Hide 
Range on Protein: 2156-2166
Range on HMM: 261-271/271
Sequence Identity: 63% (7 aa)

YNLGICFLKLG
| ||| ||.| 
YSLGIVFLELT
TPR_1 1365.AA TPR_1 2152-2171 40 0.230173 8.75 Pfam 1-20 (34) Show / Hide 
Range on Protein: 2152-2171
Range on HMM: 1-20/34
Sequence Identity: 40% (8 aa)

IHSLYNLGICFLKLGDTQNA
   .|||| |..|.|. . |
AEAWYNLGNCYYKMGNYDEA
TPR_2 1365.AA TPR_2 2152-2176 36 1.212683 6.36 Pfam 1-25 (34) Show / Hide 
Range on Protein: 2152-2176
Range on HMM: 1-25/34
Sequence Identity: 36% (9 aa)

IHSLYNLGICFLKLGDTQNAYRIFK
   .|||| | .|.|| . | . ..
AEAWYNLGQCYYKQGDYDEAIEYYE
TPR_2 1365.AA TPR_2 2194-2227 23 0.028201 12.14 Pfam 1-34 (34) Show / Hide 
Range on Protein: 2194-2227
Range on HMM: 1-34/34
Sequence Identity: 23% (8 aa)

VYFLNYFGLYYKTIGKFQVALKYLTDSLNLEEKN
.. ... |. |   |... |..|.  .| |...|
AEAWYNLGQCYYKQGDYDEAIEYYEKALKLDPNN
TPR 1365.AA TPR 2194-2227 20 0.127727 8.44 SMART 1-34 (34) Show / Hide 
Range on Protein: 2194-2227
Range on HMM: 1-34/34
Sequence Identity: 20% (7 aa)

VYFLNYFGLYYKTIGKFQVALKYLTDSLNLEEKN
.  ..  |. |   |... |..... .| |...|
AEAWYNLGNCYYKMGDYDEAIECYQKALELDPNN
TPR_1 1365.AA TPR_1 2201-2227 25 21.232759 1.89 Pfam 8-34 (34) Show / Hide 
Range on Protein: 2201-2227
Range on HMM: 8-34/34
Sequence Identity: 25% (7 aa)

GLYYKTIGKFQVALKYLTDSLNLEEKN
|. |   |... |....   | |...|
GNCYYKMGNYDEAIECYQKALELNPNN
TPR_2 1365.AA TPR_2 2236-2269 41 0.000656 17.92 Pfam 1-34 (34) Show / Hide 
Range on Protein: 2236-2269
Range on HMM: 1-34/34
Sequence Identity: 41% (14 aa)

AEINNNIGQCYHAVQDYQIAKNYYKKCYETVKNI
||. .|.|||| . .||. |..||.|. .   | 
AEAWYNLGQCYYKQGDYDEAIEYYEKALKLDPNN
TPR_1 1365.AA TPR_1 2236-2269 35 0.004397 14.75 Pfam 1-34 (34) Show / Hide 
Range on Protein: 2236-2269
Range on HMM: 1-34/34
Sequence Identity: 35% (12 aa)

AEINNNIGQCYHAVQDYQIAKNYYKKCYETVKNI
||. .|.|.||.. ..|. |  .|.|. |   | 
AEAWYNLGNCYYKMGNYDEAIECYQKALELNPNN
TPR 1365.AA TPR 2236-2269 38 0.006661 16.89 SMART 1-34 (34) Show / Hide 
Range on Protein: 2236-2269
Range on HMM: 1-34/34
Sequence Identity: 38% (13 aa)

AEINNNIGQCYHAVQDYQIAKNYYKKCYETVKNI
||. .|.|.||..  ||. | ..|.|. |   | 
AEAWYNLGNCYYKMGDYDEAIECYQKALELDPNN
TPR_1 1365.AA TPR_1 2278-2311 26 0.001865 16.05 Pfam 1-34 (34) Show / Hide 
Range on Protein: 2278-2311
Range on HMM: 1-34/34
Sequence Identity: 26% (9 aa)

ISSMNNVGICFLQEGNYVQALDHFQQNLDILKKE
    .| | |... ||| .|....|. |..  . 
AEAWYNLGNCYYKMGNYDEAIECYQKALELNPNN
TPR 1365.AA TPR 2278-2311 23 0.002613 18.24 SMART 1-34 (34) Show / Hide 
Range on Protein: 2278-2311
Range on HMM: 1-34/34
Sequence Identity: 23% (8 aa)

ISSMNNVGICFLQEGNYVQALDHFQQNLDILKKE
.   .| | |... |.| .|....|. |..  . 
AEAWYNLGNCYYKMGDYDEAIECYQKALELDPNN
TPR_2 1365.AA TPR_2 2278-2311 20 0.232233 8.9 Pfam 1-34 (34) Show / Hide 
Range on Protein: 2278-2311
Range on HMM: 1-34/34
Sequence Identity: 20% (7 aa)

ISSMNNVGICFLQEGNYVQALDHFQQNLDILKKE
    .| | | .. |.| .|...... | .  . 
AEAWYNLGQCYYKQGDYDEAIEYYEKALKLDPNN
TPR_1 1365.AA TPR_1 2320-2353 20 0.007403 13.96 Pfam 1-34 (34) Show / Hide 
Range on Protein: 2320-2353
Range on HMM: 1-34/34
Sequence Identity: 20% (7 aa)

AVCLNNLAICQLKLGQNQIALNNFLESHQIKQQI
|  ..||. |..|.|. . |.  . .  ..  . 
AEAWYNLGNCYYKMGNYDEAIECYQKALELNPNN
TPR 1365.AA TPR 2320-2353 20 0.01541 15.68 SMART 1-34 (34) Show / Hide 
Range on Protein: 2320-2353
Range on HMM: 1-34/34
Sequence Identity: 20% (7 aa)

AVCLNNLAICQLKLGQNQIALNNFLESHQIKQQI
| ...||. | .|.|. . |.. . .. ..  . 
AEAWYNLGNCYYKMGDYDEAIECYQKALELDPNN
TPR_2 1365.AA TPR_2 2320-2353 20 0.043897 11.46 Pfam 1-34 (34) Show / Hide 
Range on Protein: 2320-2353
Range on HMM: 1-34/34
Sequence Identity: 20% (7 aa)

AVCLNNLAICQLKLGQNQIALNNFLESHQIKQQI
| ...||. | .|.|. . |.. . .. ..  . 
AEAWYNLGQCYYKQGDYDEAIEYYEKALKLDPNN
TPR_1 1365.AA TPR_1 2363-2378 25 16.098061 2.31 Pfam 1-16 (34) Show / Hide 
Range on Protein: 2363-2378
Range on HMM: 1-16/34
Sequence Identity: 25% (4 aa)

EQSLKNIAQCYYNLND
 . ..|...|||....
AEAWYNLGNCYYKMGN