Gene 26270 (Tetrahymena)

26270

Species: Tetrahymena
Alias: PreTt26270, TTHERM_00751030, 969, 26270, 122.m00072
External Links: Tetrahymena Genome Database (TGD) ,
Annotation:

Classification

Group: Other
Family: Ciliate-C8
Subfamily: C8

Sequence

Name Sequence Type Origin Length Description Download
26270.AA Protein None 1137 None Fasta, JSON
26270.kin_dom Protein Kinase Domain None 70 None Fasta, JSON
26270.NA RNA None 3414 None Fasta, JSON

Protein domain

Protein domains of 26270.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Kinase 26270.AA Ciliate-B2 149-233 51 5.1e-53 123.0 In-house 108-197 (197) Show / Hide 
Range on Protein: 149-233
Range on HMM: 108-197/197
Sequence Identity: 51% (46 aa)

NMIFDLIHGLIDLQHNKILHLDIKPKNILVDYRGNYIYTDFGISEIYQEGSSMQIRGFTNKYSSQEQRNQD-----VNKISYKSDVYSLG
.|||.|| ||| .  . ||||||||.|||. . |||.|.||||| | .. .  .|.||| || | || ..|     | .| ..||.||.|
QMIFQLIDGLIQFRMYNILHLDIKPQNILFMQNGNYVYCDFGISSIKKDNQQIKIKGFTKKYASPEQMECDHNQTFVTNIDFQSDIYSMG
Kinase 26270.AA Ciliate-E1 150-230 44 2e-33 106.24 In-house 114-202 (202) Show / Hide 
Range on Protein: 150-230
Range on HMM: 114-202/202
Sequence Identity: 44% (40 aa)

MIFDLIHGLIDLQHNKILHLDIKPKNILVDYRGNYIYTDFGISE--IYQEGSSMQIRGFTNKYSSQEQRN------QDVNKISYKSDVY
.||.||.|||.|. ..|.|.||||.|||..  |||.|.|||||   .... ...|..|.|..|...|| |      .. .||.||||.|
IIFQLIDGLIELHQYNIIHRDIKPQNILINNQGNYVYCDFGISKFLKNNQNQQCQYKGYTHYYYPPEQYNCPEQEHNKNQKINYKSDIY
Kinase 26270.AA Ciliate-E3 154-240 35 3.6e-14 40.87 In-house 112-202 (202) Show / Hide 
Range on Protein: 154-240
Range on HMM: 112-202/202
Sequence Identity: 35% (33 aa)

LIHGLIDLQHNKILHLDIKPKNILVDYRGN---YIYTDFGIS-EIYQEG--SSMQIRGFTNKYSSQEQRNQDVNKISYKSDVYSLGQTLLKVI
.| |.|..   .| | |||| ||||| . |       ||| |   ...   .. |  |.|  |.. ||  |  ..||  || ||.|  .. ..
IIQGMIAIHEKNIIHSDIKPDNILVDKNNNQLIIKICDFGESKQLRKNKGHTHTQYQGWTPFYAAPEQNDQ--QQISKESDYYSVGAVFCQLC
Kinase 26270.AA C8 142-236 24 8.3e-11 33.84 In-house 120-226 (226) Show / Hide 
Range on Protein: 142-236
Range on HMM: 120-226/226
Sequence Identity: 24% (26 aa)

YEDKNNKNMIFDLIHGLIDLQHNKILHLDIKPKNILVDYRGNYI----YTDFGISEIYQEGSS-MQIRGF----TNKYSSQEQRNQ---DVNKISYKSDV
.....  ..   .| |.  ..  .|.| ||||.|.||   .||.      |||..   ..  | .|.. .    | .|.  |. ..   .. . . .||.
FSKEMKEIIAIQMIDGVNYIHCKNIMHRDIKPHNFLVCLDQNYGFEIKLCDFGFASQVSKNKSHIQSKKMNTCGTWAYFAPEIEKKQDNQYKQYRIQSDL

YSLGQTL
.|.|  |
FSVGLVL
Kinase 26270.AA Ciliate-E5 153-240 24 3.9e-10 28.98 In-house 111-271 (271) Show / Hide 
Range on Protein: 153-240
Range on HMM: 111-271/271
Sequence Identity: 24% (40 aa)

DLIHGLIDLQHNKILHLDIKPKNILVDYRGNYIYTDFGIS---------EIYQEGSS-------------------------------------------
.|. || |.  . |.|||||| |||  |     |.|.|||             | .                                            
QLVKGLQDIHQKNIIHLDIKPANILLGYDNKWKYIDMGISRKFKHVVRDKQVSEQRQNSSETIEENMIKFIKIIPYFFQREYPKLHNKNRKKLRYQIPHT

MQIRGFTNKYSSQEQ----RNQD-----------------VNKISYKSDVYSLGQTLLKVI
 .  |||  ||| ||     ||.                   ||  .||.||||   |.  
CNLKGFTQCYSSPEQYQCYHNQMFYILIRNLPDIKYIQSFKKKITKQSDIYSLGIVFLELT
Kinase 26270.AA Ciliate-C5 161-237 35 1.3e-09 27.51 In-house 112-189 (260) Show / Hide 
Range on Protein: 161-237
Range on HMM: 112-189/260
Sequence Identity: 35% (28 aa)

LQHNKILHLDIKPKNILVDYRGN-YIYTDFGISEIYQEGS-SMQIRGFTNKYSSQEQRNQDVNKISYKSDVYSLGQTLL
.|.|...| |.|| ||| | .   .. .|.| |  ...||   ...||| ||   |  ..       | |.| ||  ||
IQQNNLIHSDVKPENILYDSQEKCFNLCDYGESKSFKDGSKTYDLKGFTRKYAAPEITDD-NGFFNIKYDIYGLGIILL
Kinase 26270.AA Ciliate-E2b 154-207 31 1.4e-09 25.42 In-house 111-164 (272) Show / Hide 
Range on Protein: 154-207
Range on HMM: 111-164/272
Sequence Identity: 31% (17 aa)

LIHGLIDLQHNKILHLDIKPKNILVDYRGNYIYTDFGISEIYQEGSSMQIRGFT
.. .|  |....|.. |||| ||.||. |     |.|.. . .. ...  | ||
ICLCLEYLHNQNIIYRDIKPENIMVDHKGYMKLIDMGTAKHMYKKNEQMTRTFT
Kinase 26270.AA Ciliate-A1 154-233 29 3.8e-09 27.24 In-house 110-215 (301) Show / Hide 
Range on Protein: 154-233
Range on HMM: 110-215/301
Sequence Identity: 29% (31 aa)

LIHGLIDLQHNKILHLDIKPKNILVDYRGNYIYTDFGISEIYQEGS------------------SMQI-RGFTNKYSSQEQ-----RNQDV--NKISYKS
.| |..|.    |||.|.|| |||.     .   |.|.| .                       .  . .| .  | | ||     | |    |||. .|
IIEGYADIHDHNILHRDLKPQNILIHFDDKWKICDLGMSKQLEQNQDCCDDVNGCSFSKQVNKHYHTCKKGGNLYYMSPEQYQMHYRDQMFIENKIYKQS

DVYSLG
|.||||
DMYSLG
Kinase 26270.AA Ciliate-E2-Unclassified 163-236 31 2.2e-08 25.21 In-house 161-260 (352) Show / Hide 
Range on Protein: 163-236
Range on HMM: 161-260/352
Sequence Identity: 31% (31 aa)

HNK-ILHLDIKPKNILVDYRG---NYIYTDFGISEIYQEG----------------SSMQIRGFTNKYS----SQEQRNQDVNKIS--YKSDVYSLGQTL
|.. |.| |||| |||.|  |   .   .|||||  ||.                   |. .  |. |     . |   .  .  |  ||.|..|||  |
HKNNIIHRDIKPENILFDNNGKNYYIKIIDFGISKKYQQNNNCDTNQQQKMQIWKQQMMWTFCGTPNYMPQYTAPEVLQGQNYDHSKAYKCDIWSLGVIL
Kinase 26270.AA Ciliate-E2 148-233 22 2.7e-08 24.54 In-house 163-283 (365) Show / Hide 
Range on Protein: 148-233
Range on HMM: 163-283/365
Sequence Identity: 22% (28 aa)

KNMIFDLIHGLIDLQHNK-ILHLDIKPKNILVDYRGNYIYTDFGISEIYQEG---------SSMQIRGF------------------------TNKYSSQ
...|  .|..|  |  .. |.| |||| |||.        .|||.| .|..          . . .  .                        |  | . 
EFYIACIILALEYLHSKNNIIHRDIKPENILF-----IKIIDFGLSKKYDDDNQNRTHKQQCKWYMF-KNDTSRTPGYMDQIIQQNMFNTICGTPGYMAP

EQRN-QDVNK------ISYKSDVYSLG
|  | .. ..       .||.|..|||
EILNGKKYDNQQKQKGYDYKCDIWSLG
Kinase 26270.AA Pkinase 164-233 30 1.8e-07 27.53 Pfam 127-199 (293) Show / Hide 
Range on Protein: 164-233
Range on HMM: 127-199/293
Sequence Identity: 30% (23 aa)

NKILHLDIKPKNILVDYRGNY----IYTDFGISEI--YQEGSSMQIRGFTNKYSSQEQRNQDVNKISYKSDVYSLG
..|.| |.|| |||.| .|.       .|||...   |  .| |. .  |  | . |   .. .....|.|..|.|
MGIIHRDLKPENILIDNNGHIDACVKICDFGLAKQFDY-NNS-MTTFCGTPWYMAPEV-IRGGQYYGPKVDMWSCG
S_TKc 26270.AA S_TKc 127-289 12 0.000611 -119.13 SMART 1-231 (231) Show / Hide 
Range on Protein: 127-289
Range on HMM: 1-231/231
Sequence Identity: 12% (32 aa)

YSLDCCIGQGG--------ESL---------------------------------IYEDKNNKNMIFDLIHG--------LIDLQH--------------
| .   ||.|.        .                                   ...| ..  |..... |        . . ..              
YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIKEHIRREIQILKKHHPNIVKLYDVFQD-DHLYMVMEYCDGDLGDLFDYIKKRGRHGLRFPFPEHARFY

-------------NKILHLDIKPKNILVDYRGNYIYTDFGISEIYQEGSSMQIRGFTNKYSSQEQRNQDVNKISY-KSDVYSLGQTLLKVIERFKELNSQ
             ..|.| |.|| |||.|   .   .|||.. ..           |  | . |       . .. |.|..|.| .|   .   . . . 
MYQICCALEYCHSHGIIHRDLKPENILLDE--HIKICDFGLARQL------TTFCGTPWYMAPEVL-----GYGKCKCDWWSCGCILYEMLC-GYPPFP-

SQLIEFAKFINDIEDIVN---QRMVQEEIDQRSDCYQIHS--------RFV
 |. .  | |    . .    ... | . ..|  . ..           ..
-QMQMMFKKIG--SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF
Kinase 26270.AA Ciliate-E1 133-149 35 0.015036 4.68 In-house 1-17 (202) Show / Hide 
Range on Protein: 133-149
Range on HMM: 1-17/202
Sequence Identity: 35% (6 aa)

IGQGGESLIYEDKNNKN
||.|..|.... |...|
IGNGSFSIVFKAKQQNN