Gene 3360 (Tetrahymena)
3360
Group:
Other
Family:
Ciliate-E1
Sequence
Protein domains of 3360.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.
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| Domain | Protein name | Domain Name | Range | Identity (%) | Significance | Score | Profile Source | Profile Range (length) | Alignment |
|---|---|---|---|---|---|---|---|---|---|
| Kinase | 3360.AA | Ciliate-B2 | 350-418 | 36 | 3.1e-21 | 46.62 | In-house | 79-151 (197) | Show / Hide |
Range on Protein: 350-418 Range on HMM: 79-151/197 Sequence Identity: 36% (27 aa) VMCKCQMSLTDEIL----SKKEFSLREILRFISTAFHLLIVLRQKYIYHSDIKPGNILKIDDNNYKLSDFGAS .| ||. || .|. .|.| ... | . || .| . | | |||| |||. .||...||| | IMEKCECSLKQELQKIQKQQKCFNNQKLYQMIFQLIDGLIQFRMYNILHLDIKPQNILFMQNGNYVYCDFGIS |
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| Kinase | 3360.AA | Ciliate-E1 | 280-425 | 21 | 1.5e-19 | 60.56 | In-house | 1-163 (202) | Show / Hide |
Range on Protein: 280-425 Range on HMM: 1-163/202 Sequence Identity: 21% (35 aa) INSGGEADIFT---NKYD-DKIAYRLIQLNEEEDLNRQLNELQRFKELQEQNILNVNSSHLISNKV-KNTMYIIQVMCKCQMSLTDEIL----------- | .|.....| ... ..| .|... .. | ...|.. ..... . . .. .| . .. .|.....|..||.|.. IGNGSFSIVFKAKQQNNNYNQVAQKIINCCFNYNQNHFQDEIKEYYKIMK-FKKECYIIQIIDYIKIDQNYICIIIFECCCCSLKDYLQNHNRLEYWQQC --SKKEFSLREILRFISTAFHLLIVLRQKYIYHSDIKPGNILKIDDNNYKLSDFGASQQVNFND ...|. .... | ... || |.|. |.|.|||| |||. ...||...||| |.. . |. QQNQNQFTFQQKMQIIFQLIDGLIELHQYNIIHRDIKPQNILINNQGNYVYCDFGISKFLKNNQ |
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| Kinase | 3360.AA | Ciliate-C6 | 365-422 | 43 | 7.9e-13 | 41.8 | In-house | 129-188 (306) | Show / Hide |
Range on Protein: 365-422 Range on HMM: 129-188/306 Sequence Identity: 43% (26 aa) KKEFSLREILRFISTAFHLLIVLRQ-KYIYHSDIKPGNILKIDD-NNYKLSDFGASQQVN .. |. ||. | . .| .. | | |||| ||| .|| |||.|||||..|| . YEHFDENEIVQFCKQIGKTLADIYNECNIAHRDIKPSNILIMDDENNYYLSDFGCAQQLF |
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| Kinase | 3360.AA | Ciliate-A1 | 296-428 | 22 | 3.5e-09 | 27.34 | In-house | 27-158 (301) | Show / Hide |
Range on Protein: 296-428 Range on HMM: 27-158/301 Sequence Identity: 22% (30 aa) KIAYRLIQLNEEEDLNRQLNELQRFKELQEQNILNVNSSHLISNKVKNTMYIIQVMCKCQMSLTDEILSKKE-FSLREILRFISTAFHLLIVLRQKYIYH ... .| . | . ..|.. | . | . .. | |.|| | .|| . . .. . || . . . .. . . | | YLCCKIIICTNFEQYKNNIQEYRKCKQINHNNVIKNYQQLYYNTNNKECMFII--MEYCQYGNLFNYCYQNDYMKKEEIYEICYQIIEGYADIHDHNILH SDIKPGNILKIDDNNYKLSDFGASQQVNFNDPFC .|.||.||| .|. .|. |.| |.| .| | RDLKPQNILIHFDDKWKICDLGMSKQLEQNQDCC |
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| S_TKc | 3360.AA | S_TKc | 274-523 | 14 | 1.6e-07 | -66.72 | SMART | 1-231 (231) | Show / Hide |
Range on Protein: 274-523
Range on HMM: 1-231/231
Sequence Identity: 14% (39 aa)
FKLGDHINSGGEADIFTNKYDD---KIAYRLIQLNEEEDLNRQLNELQRFKELQEQNILNVNSSHLISNKVKNTMYIIQVMCKCQ-MSLTDEILSKKE--
......| .|. . . . . . | | .. ..|.| |. . || . . . .|.. .| .| | | ...
YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK-------EHIRREIQILKK-HHPNIVKLYDVFQD-----DHLYMVMEYCDGDLGDLFDYIKKRGRHG
----FSLREILRFISTAFHLLIVLRQKYIYHSDIKPGNILKIDDNNYKLSDFGASQQVNFNDPFCPYIMFTRGFTPQDREKNLPFYH---DIYSFGKTIQ
|. .. ... . | . .. | | |.|| ||| .|. . |..||| . |. . |. . . .. . |..|.| ..
LRFPFPE-HARFYMYQICCALEYCHSHGIIHRDLKPENIL-LDE-HIKICDFGLARQL-------TTFCGTPWYMAPEVL---GYGKCKCDWWSCGCILY
WLFT----LLKNRSEIFDRLEKFIKEIYKDDDNSINVDCFELPIKFINILMEF------TNDEVIE----AFLEEYL
... . ..|... . . ||. .... | |. . . . ...
EMLCGYPPFP-QMQMMFKKIG------------------SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF
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| Kinase | 3360.AA | MOK | 392-431 | 45 | 3.2e-07 | 18.15 | In-house | 121-159 (283) | Show / Hide |
Range on Protein: 392-431 Range on HMM: 121-159/283 Sequence Identity: 45% (18 aa) IYHSDIKPGNILKIDDNNYKLSDFGASQQVNFNDPFCPYI |.| |.|| ||| | . ||.|||. | |. || IFHRDVKPENIL-IKQDHLKLADFGSCRSVYSKQPYTEYI |
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| Kinase | 3360.AA | Ciliate-E3 | 308-424 | 27 | 2e-06 | 16.51 | In-house | 44-159 (202) | Show / Hide |
Range on Protein: 308-424 Range on HMM: 44-159/202 Sequence Identity: 27% (33 aa) EDLNRQLNELQRFKELQEQNILNVNSSHLISNKVKNTMYIIQVMCKCQMSLTDEILSKKEFSLREILRFISTAFHLLIVLRQKYIYHSDIKPGNILKIDD |... .| | .. . ||.. . . . .. . |.| .| .|. | . . .. .|. . . .| . .| | |||||| ||| .| EQFQKTQQEFQNCQQINSQNVVKCHDQ--YYDQQNKMIFIVQEYCS-NGDLYHYIK-QQNKTQNIIYDICIQIIQGMIAIHEKNIIHSDIKPDNIL-VDK NN----YKLSDFGASQQVNFN || | .|||.| | .| NNNQLIIKICDFGESKQLRKN |
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| Kinase | 3360.AA | LKB | 392-416 | 56 | 2e-06 | 15.1 | In-house | 125-149 (265) | Show / Hide |
Range on Protein: 392-416 Range on HMM: 125-149/265 Sequence Identity: 56% (14 aa) IYHSDIKPGNILKIDDNNYKLSDFG . | ||||||.| || |..||| VVHKDIKPGNLLLTHDNTLKICDFG |
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| Kinase | 3360.AA | RAN | 392-416 | 62 | 4e-06 | 16.5 | In-house | 170-195 (324) | Show / Hide |
Range on Protein: 392-416 Range on HMM: 170-195/324 Sequence Identity: 62% (17 aa) IYHSDIKPGNILKID--DNNYKLSDFG ||| |||| ||| || | | .| |.| IYHCDIKPENIL-IDGIDWNIYLCDWG |
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| Kinase | 3360.AA | Ciliate-E8 | 392-418 | 48 | 5e-06 | 14.91 | In-house | 110-138 (138) | Show / Hide |
Range on Protein: 392-418 Range on HMM: 110-138/138 Sequence Identity: 48% (14 aa) IYHSDIKPGNIL-KI-DDNNYKLSDFGAS | |.|.| ||| . || . |. ||| | IIHCDFKLNNILVQRNDDTKIKIIDFGFS |
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| Kinase | 3360.AA | Ciliate-A5 | 383-416 | 38 | 9e-06 | 16.09 | In-house | 111-144 (275) | Show / Hide |
Range on Protein: 383-416 Range on HMM: 111-144/275 Sequence Identity: 38% (13 aa) LLIVLRQKYIYHSDIKPGNILKIDDNNYKLSDFG .. .|.|. |.| ||.| ||. .|. .|| |.. VCMYLQQNNICHGDIRPQNICLTQDGQVKLMDMN |
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| Kinase | 3360.AA | Ciliate-A5 | 282-331 | 17 | 0.007266 | 5.88 | In-house | 1-51 (275) | Show / Hide |
Range on Protein: 282-331 Range on HMM: 1-51/275 Sequence Identity: 17% (9 aa) SGGEADIFTN-KYDDKIAYRLIQLNEEEDLNRQLNELQRFKELQEQNILNV .|. |. | . . .. ..|.. | . ... ..|| .||... FYGCMKIWKNQHQQEYYICKQKQIQDEDRQKHFQQYFEQRMQLQHPNIVKL |
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