Gene 3362 (Tetrahymena)
3362
Group:
Other
Family:
Ciliate-E1
Sequence
Protein domains of 3362.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.
Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.
| Domain | Protein name | Domain Name | Range | Identity (%) | Significance | Score | Profile Source | Profile Range (length) | Alignment |
|---|---|---|---|---|---|---|---|---|---|
| LRR_RI | 3362.AA | LRR_RI | 21-48 | 39 | 0.000456 | 20.76 | SMART | 1-28 (28) | Show / Hide |
Range on Protein: 21-48 Range on HMM: 1-28/28 Sequence Identity: 39% (11 aa) NIQVLTLWLYNNSIGPEGVSILSKSLAN | ..||| || .|.||. |...|. NCSLRELWLSNNKLGDEGCRQLCEGLKH |
|||||||||
| LRR_RI | 3362.AA | LRR_RI | 81-108 | 50 | 0.000228 | 21.76 | SMART | 1-28 (28) | Show / Hide |
Range on Protein: 81-108 Range on HMM: 1-28/28 Sequence Identity: 50% (14 aa) NMSKLILYLSSNKIGDMGAQNLCSALKK |.| . |.||.||.|| |.. ||..|| NCSLRELWLSNNKLGDEGCRQLCEGLKH |
|||||||||
| Kinase | 3362.AA | Ciliate-E1 | 628-801 | 18 | 2.4e-22 | 69.79 | In-house | 1-202 (202) | Show / Hide |
Range on Protein: 628-801 Range on HMM: 1-202/202 Sequence Identity: 18% (38 aa) INSGGEADIFTHAYDESI---AYRVIKLDEDE-DLNEQLLELYSIKELQEQNILDLNTSHLVEDKD-NDTKYIIHVMQKCQMSLQDEIS----------- | .|.....| ..... . .| . .. . |... |.. ...... . .. ... .. . . .| ....|..||.|... IGNGSFSIVFKAKQQNNNYNQVAQKIINCCFNYNQNHFQDEIKEYYKIMK-FKKECYIIQIIDYIKIDQNYICIIIFECCCCSLKDYLQNHNRLEYWQQC --SKKVFSLREILRFISTAFHLLIVLRQKYIYHSDIKPGNILKIDDNNYKLSDFGASQ-----LVNFIDPFCDFKMYTPGFIPQ------NQSLDLPFYH .. |. .... | ... || |.|. |.|.|||| |||. ...||...||| |. . .. .. ..| | . |.. . QQNQNQFTFQQKMQIIFQLIDGLIELHQYNIIHRDIKPQNILINNQGNYVYCDFGISKFLKNNQNQQCQYKGYTHYYYPPEQYNCPEQEHNKNQKINYKS DIY ||| DIY |
|||||||||
| Kinase | 3362.AA | Ciliate-B2 | 622-804 | 25 | 7e-20 | 43.35 | In-house | 1-197 (197) | Show / Hide |
Range on Protein: 622-804 Range on HMM: 1-197/197 Sequence Identity: 25% (51 aa) FQLGDHINSGGEADIFTHAYDES-IAYR--VIKLDED-EDLNEQLLEL-YSIKELQEQNILDLNTSHLVEDKDNDTKYIIHVMQKCQMSLQDEIS----S . |.. ||.||. |. .| |. ..| .. .| ... .. ..| . |.|| | ... . . . .|.||. ||..|. YYLCKYINKGGCGFICEGYKKHSIREYQDLAFKIYFNKQDCDKEEIQHEIKIMKMFEYNI---NVVKYIDHIQINETIDVLIMEKCECSLKQELQKIQKQ KKVFSLREILRFISTAFHLLIVLRQKYIYHSDIKPGNILKIDDNNYKLSDFGASQLVNFIDPFCDFKMYTPGFIPQNQSLDL---------PFYHDIYSF .| | ... | . || .| . | | |||| |||. .||...||| | . . . | | . . | . | |||| QKCFNNQKLYQMIFQLIDGLIQFRMYNILHLDIKPQNILFMQNGNYVYCDFGISSIKK-DNQQIKIKGFTKKYASPEQMECDHNQTFVTNIDFQSDIYSM G | G |
|||||||||
| Kinase | 3362.AA | Ciliate-C6 | 713-767 | 43 | 1.2e-11 | 37.54 | In-house | 129-185 (306) | Show / Hide |
Range on Protein: 713-767 Range on HMM: 129-185/306 Sequence Identity: 43% (25 aa) KKVFSLREILRFISTAFHLLIVLRQ-KYIYHSDIKPGNILKIDD-NNYKLSDFGASQ .. |. ||. | . .| .. | | |||| ||| .|| |||.|||||..| YEHFDENEIVQFCKQIGKTLADIYNECNIAHRDIKPSNILIMDDENNYYLSDFGCAQ |
|||||||||
| Kinase | 3362.AA | Ciliate-E3 | 732-766 | 51 | 2.5e-08 | 22.38 | In-house | 116-153 (202) | Show / Hide |
Range on Protein: 732-766 Range on HMM: 116-153/202 Sequence Identity: 51% (20 aa) LIVLRQKYIYHSDIKPGNILKIDDNN----YKLSDFGAS .| . .| | |||||| ||| .| || | .|||.| MIAIHEKNIIHSDIKPDNIL-VDKNNNQLIIKICDFGES |
|||||||||
| Kinase | 3362.AA | S_TKc | 622-872 | 14 | 3.5e-07 | -71.52 | SMART | 1-231 (231) | Show / Hide |
Range on Protein: 622-872
Range on HMM: 1-231/231
Sequence Identity: 14% (40 aa)
FQLGDHINSGGEADIFT---HAYDESIAYRVIKLDEDEDLNEQLLELYSIKELQEQNILDLNTSHLVEDKDNDTKYIIHVMQKCQM---SLQDEISSKKV
......| .|. . . . .. | .|| . . |. |. . || | . ... || | .| | | ...
YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK-------EHIRREIQILKK-HHPNIVKLYDVFQD-------DHLYMVMEYCDGDLGDLFDYIKKRGR
------FSLREILRFISTAFHLLIVLRQKYIYHSDIKPGNILKIDDNNYKLSDFGASQLVNFIDPFCDFKMYTPGFIPQNQSLDLPFYH---DIYSFGKT
|. .. ... . | . .. | | |.|| ||| .|. . |..||| . .. . || ... .. . |..|.| .
HGLRFPFPE-HARFYMYQICCALEYCHSHGIIHRDLKPENIL-LDE-HIKICDFGLARQL-------TTFCGTPWYMAPEVL---GYGKCKCDWWSCGCI
IQKLLM-----QLENQSEISDCLNKFIDEEICKDDKNSINLDCFELPRKFINILMNFVNYEVI-----EAFL-------EEYL
. .| . .. ..| .. ....... ... ||. ...
LYEMLCGYPPFP-----QMQMMFKKIG-------------------SPEAKDFIRKCLQKDPEKRPTAEALQDEWDIKCHPWF
|
|||||||||
| Kinase | 3362.AA | Ciliate-A1 | 645-777 | 20 | 5.4e-07 | 19.77 | In-house | 28-159 (301) | Show / Hide |
Range on Protein: 645-777 Range on HMM: 28-159/301 Sequence Identity: 20% (28 aa) IAYRVIKLDEDEDLNEQLLELYSIKELQEQNILDLNTSHLVEDKDN--DTKYIIHVMQKCQMSLQDEISSKKV-FSLREILRFISTAFHLLIVLRQKYIY .. .|. . | . . . |. .| . | . . ......| .|| | .|| .. . . . || . . . .. . . | LCCKIIICTNFEQYKNNIQEYRKCKQINHNNVIKNY--QQLYYNTNNKECMFII--MEYCQYGNLFNYCYQNDYMKKEEIYEICYQIIEGYADIHDHNIL HSDIKPGNILKIDDNNYKLSDFGASQLVNFIDPFCD |.|.||.||| .|. .|. |.| |. . || HRDLKPQNILIHFDDKWKICDLGMSKQLEQNQDCCD |
|||||||||
| Kinase | 3362.AA | LKB | 740-764 | 56 | 2e-06 | 15.1 | In-house | 125-149 (265) | Show / Hide |
Range on Protein: 740-764 Range on HMM: 125-149/265 Sequence Identity: 56% (14 aa) IYHSDIKPGNILKIDDNNYKLSDFG . | ||||||.| || |..||| VVHKDIKPGNLLLTHDNTLKICDFG |
|||||||||
| Kinase | 3362.AA | RAN | 740-764 | 62 | 4e-06 | 16.5 | In-house | 170-195 (324) | Show / Hide |
Range on Protein: 740-764 Range on HMM: 170-195/324 Sequence Identity: 62% (17 aa) IYHSDIKPGNILKID--DNNYKLSDFG ||| |||| ||| || | | .| |.| IYHCDIKPENIL-IDGIDWNIYLCDWG |
|||||||||
| Kinase | 3362.AA | Ciliate-E8 | 740-766 | 48 | 5e-06 | 14.91 | In-house | 110-138 (138) | Show / Hide |
Range on Protein: 740-766 Range on HMM: 110-138/138 Sequence Identity: 48% (14 aa) IYHSDIKPGNIL-KI-DDNNYKLSDFGAS | |.|.| ||| . || . |. ||| | IIHCDFKLNNILVQRNDDTKIKIIDFGFS |
|||||||||
| Kinase | 3362.AA | KHS | 622-766 | 28 | 6e-06 | 15.86 | In-house | 1-143 (258) | Show / Hide |
Range on Protein: 622-766 Range on HMM: 1-143/258 Sequence Identity: 28% (43 aa) FQLGDHINSGGEADIF---THAYDESIAYRVIKLDEDEDLNEQLLELYSIKELQEQNILDLNTSHLVEDKDNDTKYIIHVMQKCQM-SLQDEISSKKVFS ..| .. || |.. . || | .|||.. ..|. |. .|. . ||. | | .|| . .| | |||| | YELLQRVGSGTYGDVYKARDIQSDELAAVKVIKMEPGDDFAVIQQEIMMMKDCRHPNIVAYFGSYLRRDK------LWICMEYCGGGSLQDIYHVTGPLS LREILRFISTAFHLLIVLRQKYIYHSDIKPGNILKIDDNNYKLSDFGAS . | . . | | .. | ||| ||| |. . || ||| | ELQIAYVCRETLQGLHYLHSMGKMHRDIKGANILLTDQGDVKLADFGVS |
|||||||||
| Kinase | 3362.AA | Ciliate-A5 | 731-764 | 38 | 9e-06 | 16.09 | In-house | 111-144 (275) | Show / Hide |
Range on Protein: 731-764 Range on HMM: 111-144/275 Sequence Identity: 38% (13 aa) LLIVLRQKYIYHSDIKPGNILKIDDNNYKLSDFG .. .|.|. |.| ||.| ||. .|. .|| |.. VCMYLQQNNICHGDIRPQNICLTQDGQVKLMDMN |
|||||||||
| LRR_RI | 3362.AA | LRR_RI | 1439-1468 | 26 | 0.044769 | 8.06 | SMART | 1-28 (28) | Show / Hide |
Range on Protein: 1439-1468 Range on HMM: 1-28/28 Sequence Identity: 26% (8 aa) SQDLVKLSLNLSKNQVKIEGVMSIANALEN .. | . |.|| | . .||.. ....|. NCSLRE--LWLSNNKLGDEGCRQLCEGLKH |
|||||||||
| LRR_RI | 3362.AA | LRR_RI | 1472-1498 | 32 | 0.059269 | 7.2 | SMART | 1-28 (28) | Show / Hide |
Range on Protein: 1472-1498 Range on HMM: 1-28/28 Sequence Identity: 32% (9 aa) LTSLELL-LKCNLISDEGIYSIASALNM ..||. | | .| . |||. ....| NCSLRELWLSNNKLGDEGCRQLCEGLKH |
|||||||||
| LRR_RI | 3362.AA | LRR_RI | 1501-1528 | 28 | 0.145363 | 4.45 | SMART | 1-28 (28) | Show / Hide |
Range on Protein: 1501-1528 Range on HMM: 1-28/28 Sequence Identity: 28% (8 aa) NIAKLSLNLSLNNIEIEGAMILASAFEN | . |.|| |.. .||.. |... . NCSLRELWLSNNKLGDEGCRQLCEGLKH |
|||||||||