Gene 10195 (Tetrahymena)
10195
Sequence
Protein domains of 10195.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.
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| Domain | Protein name | Domain Name | Range | Identity (%) | Significance | Score | Profile Source | Profile Range (length) | Alignment |
|---|---|---|---|---|---|---|---|---|---|
| Kinase | 10195.AA | CDPK | 51-305 | 48 | 5.2e-186 | 575.22 | In-house | 1-271 (271) | Show / Hide |
Range on Protein: 51-305 Range on HMM: 1-271/271 Sequence Identity: 48% (132 aa) YKFLKELGSGAFGVVFLATHR-ITGDER-AVKAVAKDRLSDKQ---QFQDEINILKELDHPNIIKLYEVYESESTIYLVTE--YCEGGELFQYVVQNKRL ||. |.||.|.||.|....|. .|..|| |.| ..|.|..||. ||. ||.|||.||||||||.||.|. | .|.|.| ||.|||||.|....... YKIKKVLGKGHFGQVRKVKHKQKTNQERVAMKIIPKSRVKDKEQQQQFFNEIEILKQLDHPNIIKIYEFYQDEKNYYIVMETEYCTGGELFDYIIEKGHF QEKDAALIMRQLFSAVSYIHDNGVIHRDLKPENFLLKKKSDPT----TIKMIDFGISKKFKK-----GEVLRQQSGTPYYIAPEVIEGQYSEQVDNWALG .||.||.||||..|||.|.|.|...||||||||.|...|.|.. .||.||.|.||||.. .....|. ||||||||||....| |..|.| .| TEKEAAYIMRQILSAVNYCHSNNIVHRDLKPENILFDSKKDDSWVIYNIKVIDWGTSKKFDQNQKIEDKKMSQRCGTPYYIAPEVLQKKYNEKCDIWSCG VILYILLSGTPPFYGKNAQEIFYSIRKCNYNLNLKAFLECSNEVRDLISRLLVKNPKKRLCDIDCYNHPWV |||||||.|.||||||| |||.....|..|... . . ..|.| .|||...|...||||... ....|||. VILYILLCGYPPFYGKNDQEIMEKVKKGKYSFEGPEWDHISDEAKDLIRKMLCYDPKKRMSAQQALQHPWF |
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| Kinase | 10195.AA | Ciliate-E2a | 51-305 | 43 | 2.5e-163 | 484.57 | In-house | 1-275 (275) | Show / Hide |
Range on Protein: 51-305 Range on HMM: 1-275/275 Sequence Identity: 43% (120 aa) YKFLKELGSGAFGVVFLATHRITGDERAVKAVAKDRLSDKQ----QFQDEINILKELDHPNIIKLYEVYESESTIYLVTEYCEGGELFQYVVQNKRLQEK |||.|..|.|.||.|.||.|..||...|.|.. | ..... .|..||||...||||||||||||||.|...|||.||||||||... .|.||..|. YKFIKKIGKGNFGSVYLAQHKQTGKQFAMKKFIK-KMYQQKKGKEYFMNEINIMRQLDHPNIIKLYEVYEDENNYYLVMEYCEGGELYDKIKQCKRFFEE --DAALIMRQLFS-AVSYIHDNGVIHRDLKPENFLLK---KKS-DPTTIKMIDFGISKKF--KKGEVLRQQSGTPYYIA------PEVIEGQ-YSEQVDN ... ||.||.. ...|.| ....||||||||.|.| |.| ... ||.|||| .... ...... |. |||.|.| .||.... |....| IQEICDIMQQLLWQGLHYMHQRNIMHRDLKPENILFKNCSKNSIQNSDIKIIDFGLATFIDKDEKKYMFQKCGTPGYVAPEVLNNKEVLKHKQYDTKCDM WALGVILYILLSGTPPFYGKNAQEIFYSIRKCNYNLNLKA-FLECSNEVRDLISRLLVKNPKKRLCDIDCYNHPWV | .|||.||||.|.|||.||...||.....||....| . ...||.| ||....|.|.||||.. ....||||. WSCGVIFYILLCGKPPFKGKTYNEILQQNKKCKIDFNCPECWEKCSKECKDLMKKMLEKDPKKRITAQQALNHPWF |
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| Kinase | 10195.AA | CAMK1 | 51-305 | 43 | 8.3e-135 | 394.33 | In-house | 1-276 (276) | Show / Hide |
Range on Protein: 51-305 Range on HMM: 1-276/276 Sequence Identity: 43% (120 aa) YKFLKELGSGAFGVVFLATHRIT---GDERAVKAVA-KDRLSDK-----QQFQDEINILK---ELDHPNIIKLYEVYESESTIYLVTEYCEGGELFQYVV |.| ||.|.|||..|.|.||. | |.. |.|. |. .. | .... ||.|.| ..|||||||.||.|||.. .|||.|.. ||||| .| YEFGKEIGRGAFSEVYLCTHKETQTNGKQYAIKCIDKKKFMKKKDMQKQEALENEIEIMKKVSKIDHPNIIKFYEWYESDNHFYLVMELVTGGELFDRIV QNKRLQEKDAALIMRQLFSAVSYIHDNGVIHRDLKPENFLLKKKSDPTTIK--MIDFGISKKFKKGE-VLRQQSGTPYYIAPEVIEG----QYSEQVDNW ... ||||..||.|..||| |.|..|. |||||||| |.. |.. .|| .|||.||.|. .| .. .. |||.|.||||.|. |. .| | EKGNYTEKDARHIMKQILSAVEYMHSKGIVHRDLKPENLLYYDKDEDSKIKRSIADFGLSKIFDHDENLMKTACGTPGYVAPEVLECKKDKPYDKACDMW ALGVILYILLSGTPPFYGKN-AQEIFYSIRKCNYNLNLKAFLECSNE-VRDLISRLLVKNPKKRLCDIDCYNHPWV |||.|||| | ||||..| .|.| | || |. . . . |.. . |.|. .|...||||.. .| ||||. SIGVITYILLCGYPPFYDENVDNELFEKIKKCEYEFPSPWWDNISDQEAKDFIKHMLEVDPKKRYTCEQCLNHPWI |
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| Kinase | 10195.AA | CAMK | 56-305 | 28 | 2.8e-126 | 409.17 | In-house | 1-425 (425) | Show / Hide |
Range on Protein: 56-305
Range on HMM: 1-425/425
Sequence Identity: 28% (121 aa)
ELGSGAFGVVFLATHRITG------------DERAVKAVAKDRLS----------------------------DKQQFQDEINILKE-------LDHPNI
.||.|.||.|.|..|. |. . |.| . |..|. |..... ||.|.| ||||||
TLGRGSFGKVKLCIHKNTTGKERVHHIYTNGQKVAIKIIDKKKLKDKQNQDYSNCYKIDKSKCKHRYCWRRPKDRKNVRREIEIMKKLQGIGNKLDHPNI
IKLYEVYE------------SEST--------IYLVT---EYCEGGEL----FQYVVQN---------------KRLQEKDAALIMRQLFSAVSYIHDNG
|||||||| . |. .|.|. |||.|||| |.|.|.. .|..|..|. ..||. ||| |.|...
IKLYEVYEDPHYFKNTNDYET-SKQVFTKDKHMYMVMEIMEYCSGGELFDDLFDYIVEHGCYGEEFDQFDIVERGRFTEREARRYFRQICSAVHYCHSHN
VIHRDLKPENFLLKKKSDPT--------------TIKMIDFGISKKFKK------------------------GEVLRQQSGTPYYIA-PEVIEGQ----
..|||||||| || ...| . .|| |||| ..||.. |. .. . |||.|.| |||..|.
IVHRDLKPENILLDDNNDDSDPVEHDEIFDWNNNNIKIIDFGFANKFDPGENNFMCSDYKGGEMHNQWTTPTEGQKMKTFCGTPEYMAAPEVLNGKGHCN
-----------YSEQVDNWALGVILYILLSGTPPFYGK-------------NAQEIFYSIRKCNYNLNLKAFLE--------------------CSNEVR
|....| |..||||||.|.|.|||||. | .|.| |.|..|. . | . .| |..
MQNATDEEKPYYGPKCDMWSCGVILYIMLCGYPPFYGDCDNEICEDEWIGMNDYELFEKIMKGKYDFPPPYFSPISCNYGPEWWDDISDEFHHFVSQECK
DLISRLLVKNPKKRLCDIDCYNHPWV
|||...|...|.||. .| ||||.
DLIRKMLQVDPEKRMTIEQCLNHPWM
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| Kinase | 10195.AA | S_TKc | 51-305 | 35 | 2.6e-107 | 363.71 | SMART | 1-231 (231) | Show / Hide |
Range on Protein: 51-305 Range on HMM: 1-231/231 Sequence Identity: 35% (96 aa) YKFLKELGSGAFGVVFLATHRITGDERAVKAVAKDRLSDKQQFQDEINILKELDHPNIIKLYEVYESESTIYLVTEYCEG--GELFQYVVQNKR------ |..|...|.||||.|....|. || . |.| . .... ||.|||. .||||.|||.|... . .|.|.|||.| |.||.| ....| YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK-------EHIRREIQILKK-HHPNIVKLYDVFQD-DHLYMVMEYCDGDLGDLFDYIKKRGRHGLRFP LQEKDAALIMRQLFSAVSYIHDNGVIHRDLKPENFLLKKKSDPTTIKMIDFGISKKFKKGEVLRQQSGTPYYIAPEVIEGQYSE-QVDNWALGVILYILL . | .|. .|.|...|. |.|..|.||||||||| || . .|| .|||..... . . |||.|.||||. .|. .| |..|.|||..| FPE-HARFYMYQICCALEYCHSHGIIHRDLKPENILLDE-----HIKICDFGLARQL------TTFCGTPWYMAPEVL--GYGKCKCDWWSCGCILYEML SGTPPFYGKNAQEIFYSIRKCNYNLNLKAFLECSNEVRDLISRLLVKNPKKRLCDIDCYN-------HPWV .| |||. . |..| |. | |..|.|...|.|.|.||. .. . |||. CGYPPFP--QMQMMFKKIG--------------SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF |
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| Kinase | 10195.AA | CAMKL | 51-305 | 36 | 2.9e-107 | 343.4 | In-house | 1-297 (297) | Show / Hide |
Range on Protein: 51-305 Range on HMM: 1-297/297 Sequence Identity: 36% (111 aa) YKFLKELGSGAFGVVFLATH-RITGDERAVKAVAKDRLS-DKQQFQD--------------EINILKELD---HPNIIKLYEVYESEST------IYLVT |...|.|| |.||.| |||| |.|| . |.| . |.... | . . ||.|.| |. ||||||||||.| ... ||||. YRIGKTLGKGSFGKVKLATHIRTTGEKVAIKIIDKKKIWNDPWMKKNKCGQKHESDMRIRREIQIMKMLNIGKHPNIIKLYEVIETPEHDIETKKIYLVM EYCEGGE--LFQYVVQN----KRLQEKDAALIMRQLFSAVSYIHDNGVIHRDLKPENFLLKKKSDPTTIKMIDFGISKKFKK-----GEVLRQQSGTPYY |||.||| ||.|.|.. .|..|..| . ||. |||.|.|..|..|||.|||| || .. . .|| |||| | .... |. |. . |.| | EYCSGGEMDLFDYIVKHGHRRGRMPEHEARRYFRQIVSAVNYCHSHGIVHRDIKPENILLDENGNN-NIKIIDFGFSNMYRPCIFGPGQKLKTFCGSPPY IAPEVIEG--Q-YS-EQVDNWALGVILYILLSGTPPFYGKN----AQEIFYSIRKCNYNLNLK--AFLECSNEVRDLISRLLVKNPKKRLCDIDCYNHPW |||...| . | .|| |..||||| .. |. || . . .. . .. . . . ... | ..||||...|..||.|| . |||| MAPEIFQGNNKPYDGPKVDIWSCGVILYAMVCGYLPFDDDTYNKQGKDNI-YLYWKIMCG-YYPPIWYHVS-DCRDLIRKMLQVNPEKRPTIHQIMNHPW V . M |
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| Kinase | 10195.AA | Pkinase | 51-305 | 32 | 7.2e-97 | 332.91 | Pfam | 1-293 (293) | Show / Hide |
Range on Protein: 51-305 Range on HMM: 1-293/293 Sequence Identity: 32% (96 aa) YKFLKELGSGAFGVVFLATHRITGDERAVKAVAKDRLSDKQQFQD----EINILKELDHPNIIKLYEVYESESTIYLVTEYCEGG----ELFQYVV--QN |.... .|||.||.|....|. ||.. ||| . |.. ..... .. || |.|.|.||||..||...|... ||.|.|||||| .|| |. .. YHIGRKIGSGSFGCVYKCHHKGTGKIVAVKIIKKRHEKSWKDQTHRRLSEIQIMKRLNHPNIVRLYDWFEDKDHIYMVMEYCEGGLYVMDLFDYISTWRH KRL--QEKDAALIMRQLFSAVSYIHDNGVIHRDLKPENFLLKKKSDP-TTIKMIDFGISKK--FKKGEVLRQQSGTPYYIAPEVIE--GQYSEQVDNWAL ... .|... .|.|..... |.|..|.|||||||||.|.... .. ...| .|||..|. ... . |||.|.||||| |. || |.. GCFYFSEWECKFYMYQILRGLEYCHSMGIIHRDLKPENILIDNNGHIDACVKICDFGLAKQFDY-NNS-MTTFCGTPWYMAPEVIRGGQYYGPKVDMWSC GVILYILLSGTPPFYGK------NAQEIFYSIRKCNYNLNLKAFLECS-----------------NEVRDLISRLLVKNPKKRLCDIDCYNHPWV |.|||..|.| |||.|. . ..... |... . . . | | .|.|...| |.||||. .. .|||. GCILYEMLCGRPPFPGHCWHDNHDQMQMICRIMGPPLHFDWPWWCSISYFFFRHWHFHWTFHNWSEECKDFIKWCLCKDPKKRPTAEQILQHPWF |
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| Kinase | 10195.AA | Ciliate-E2 | 51-305 | 26 | 1.6e-94 | 320.37 | In-house | 1-365 (365) | Show / Hide |
Range on Protein: 51-305 Range on HMM: 1-365/365 Sequence Identity: 26% (102 aa) YKFLKELGSGAFGVVFLATHRITGDER------------------AVKAVAKDRL--SDKQQFQDEINILK----------------ELDHPNIIKLYEV |||.| .|.|.||.|...... .. . ..| .|. .. ....|. ||.|.. .|.||||||.||. YKFIKKIGQGNFGSVYKCKVWKVQKQFAIKIIDQKQQRQQMQEKVKIKIYAMKIMKKNQIEQIKQEIHIMREINCFYKKINEKNILEQLNHPNIIKMYEC YE--SESTIYLVTEYCEGGELFQYVVQN-----------KRLQEKDAALIMRQLFS---------------AVSYIHDNG-VIHRDLKPENFLLKKKSDP .. ....||||.|||.||.||.| .| |.. || .. ||.|... |. |.| .. .||||.|||| |. FQEKDDNNIYLVMEYCQGGDLFDYIKNNKKKRNHEIEKDKYFTEKEIKYIMKQILQGFKTKAEFYIACIILALEYLHSKNNIIHRDIKPENILF------ TTIKMIDFGISKKFKKG--------------------------------EVLRQQSGTPYYIAPEVIEGQ----------YSEQVDNWALGVILYILLSG || ||||.|||... .. ... |||.| |||...|. |....| |.||||||..|.| --IKIIDFGLSKKYDDDNQNRTHKQQCKWYMFKNDTSRTPGYMDQIIQQNMFNTICGTPGYMAPEILNGKKYDNQQKQKGYDYKCDIWSLGVILYEMLFG TPPFYGKNAQEIFYSIRKCNYNLNLK--------------AFLECSNEVRDLISR----LLVKNPKKRLC-DIDCYNHPWV ||| . | .|..... . ....|.|. |||.. .|.|.|.||. .. |||| KPPF--------QQQIKQCKIDFPCPEWQKDTQCIQCKWKSWKKWSQECKDLIKKFGKRMLQKDPEKRITGWEQILNHPWF |
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| Kinase | 10195.AA | AMPK | 51-305 | 41 | 2.1e-93 | 277.67 | In-house | 1-254 (254) | Show / Hide |
Range on Protein: 51-305 Range on HMM: 1-254/254 Sequence Identity: 41% (108 aa) YKFLKELGSGAFGVVFLATHRITGDERAVKAVAKDRL---SDKQQFQDEINILKELDHPNIIKLYEVY-ESESTIYLVTEYCEGGELFQYVVQNKRLQEK | | .| |.|| | ..|| .|| . |.| |... .... | || ||| . ||.||.|||| |... |..|.|| ||||| |.|...||||. YIIGKTIGEGTFGKVKMGTHILTGEKVAIKILNKQKIKDQDMVERIQREIHILKLFRHPHIIQLYEVIIETPTDIFMVMEYVSGGELFDYIVKHGRLQER DAALIMRQLFSAVSYIHDNGVIHRDLKPENFLLKKKSDPTTIKMIDFGISKKFKKGEVLRQQSGTPYYIAPEVIEGQ--YSEQVDNWALGVILYILLSGT .|. . | |.|.|.|.... |||||||| || .. || ||| |. |.|| |. | | | |||.|.|. . .|| | ||||| .| |. EACRFFQQIISGVEYCHRHMIVHRDLKPENLLLDHN---KNIKIVDFGLSNMMKDGEFLKTACGSPCYAAPEMISGKLYCGPEVDIWSCGVILYAMLCGY PPFYGKNAQEIFYSIRKCNYNLNLKAFLECSNEVRDLISRLLVKNPKKRLCDIDCYNHPWV || | . . |... | . .||. |..|||...| ..| ||. | |||| LPFDDENTPTLYKKIKNGEYYIP--KFLSP--EAKDLIKHMLQVDPMKRITIHDIRNHPWF |
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| Kinase | 10195.AA | CAMK-Unique | 51-305 | 26 | 2.4e-93 | 308.51 | In-house | 1-363 (363) | Show / Hide |
Range on Protein: 51-305
Range on HMM: 1-363/363
Sequence Identity: 26% (98 aa)
YKFLKELGSGAFGVVFLATHRITGDERAVKAVAK---DRLSDKQQ-----------------FQDEINILKELDHPNIIKLYEV----YESES-------
||... .|.|.||.|. .. | ||...|.| | | . . ||| . |..|.| .|||||||||.. .. .
YKMHRIIGHGNFGHVYECMDRETGKKWACKMVKKQTHGNKKQKQQRNFDLRYKITEKRRDMKLKREHQIWKMVDHPNIIKLYDWNNPIFCDRKYPLCDLI
--------TIYLVTEYCEGGELFQYVVQ--------------------NKRLQE--KDAALIMRQLFSAVSYIHDNGVIHRDLKPENFLLKKKSD-----
.|.|.|||.||.||..... . .. | |...||..| |||.| |.....|||||.|| .... .
IKTPRALPYMYIVMEYCQGGDLFDWIQKWDEFYFNFIIKFDFNILKRCQGHFSERCWDTCFIMQCLLSAVAYMHSQDIVHRDLKLENIMVCYSFKDNNHH
--------PTTIKMIDFGISKKFKKGEVLR---QQSGTPYYIAP--------------EVIE-GQYSEQV----DNWALGVILYILLSGTPPFYGKNAQ-
. || .|||..... .. |||.|.|| |||. |..|. | |.||||.|..|.| |||.. .
RDFPYDWSNWHIKLCDFGLCCHYNHNKMCHMMQTMCGTPCYMAPEIVFCKNYQEMTRDEVINMQCYDQQCSPASDIWSLGVIMYYMLCGCPPFDCECEDR
-------EIFYSIRKCNY-NLNLKAFLE---CSNEVRDLISRLLVKNPKKRLCDIDCYNHPWV
||| .|.|..| |. |.. |.| |.. .... |..|. . |.|.
DYENHDKEIFECICKGDYCNFDWKMWHGPDYISQEAKDFVKCCMTVDPDHRWSAKELLEHQWI
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| Kinase | 10195.AA | MARK | 51-305 | 40 | 3.3e-93 | 305.03 | In-house | 1-262 (262) | Show / Hide |
Range on Protein: 51-305 Range on HMM: 1-262/262 Sequence Identity: 40% (109 aa) YKFLKELGSGAFGVVFLATHRITGDERAVKAVAKDRLSD---KQQFQDEINILKELDHPNIIKLYEVYE--SEST-IYLVTEYCEGGELFQYVVQN--KR ||.||..| |....| ||.|. || . |.| . | .|.| .. .. ||.|.| |||||||||..| | |.. |||. ||..||||..|... | YKMLKTIGHGSYAKVKLACHKHTGRKVAIKIYEKFKLNDPQWMKNVMREIEIMKKLDHPNIIKLFHVIEQDTEQHQIYLIMEYASGGELYDYIKAHPNGR LQEKDAALIMRQLFSAVSYIHDNGVIHRDLKPENFLLKKKSDPT--TIKMIDFGISKKFKKGEVLRQQSGTPYYIAPEVIEGQ-YS-EQVDNWALGVILY |.|..| | ||. |||.| |.....|||.|||| |. .. . || |||| | ... |. | ||| | |||..... | || |.|||.|| LHEEEARRIFRQIVSAVNYCHSKNIVHRDIKPENILIDEN---GNHNIKIIDFGFSICIPPGQKLNTFCGTPPYMAPEIFLKKPYDGPKVDIWSLGVVLY ILLSGTPPFYGKN--AQEIFYSIRKCNYNLNLKAFLECSNEVRDLISRLLVKNPKKRLCDIDCYNHPWV ....|. || |.. |.. |....| . | | |.||.|||. ||..| .. .|||. FMVCGYFPFDGDTQDYKELYKKILRGKYDIPCH----VSKECRNLIQRLLTVNPEERPTIEEIMKHPWM |
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| Kinase | 10195.AA | RSK | 54-305 | 35 | 2.7e-83 | 283.03 | In-house | 1-278 (278) | Show / Hide |
Range on Protein: 54-305 Range on HMM: 1-278/278 Sequence Identity: 35% (98 aa) LKELGSGAFGVVFL---ATHRITGDERAVKAVAKDRLSDKQQ----FQDEINILKELD-HPNIIKLYEVYESESTIYLVTEYCEGGELFQYVVQNKR--- ||.|| |..| ||| ||. || . |.| . | . .| |.|||.. ||.|..|..... |. .||..|||.||||| . |. LKVLGQGGYGKVFLCRKCTHHDTGQIYAMKVLKKAKIVQRQKDTRHTMTERNILERCQQHPFIVTLHYAFQTEGKLYLIMEYCRGGELFTHLQKEKHFGC LQEKDAALIMRQLFSAVSYIHDNGVIHRDLKPENFLLKKKSDPTTIKMIDFGISKKF--KKGEVLRQQSGTPYYIAPEVIE----GQ-YSEQVDNWALGV . |..|. .|... .||...|. |.||||||||| |. .|.. .|| .||| .|.| .... . .| |.|||.. . .....| | ||| FSEDEACFYMAEIVLAVEHLHQQGIIHRDLKPENILYDDESNEGHIKLTDFGFCKQFRCDHNQWTMTFCYTIEYMAPEMLKRANQQGGHDKACDWWSLGV ILYILLSGTPPFYG---KNAQEIFYSIRKCNYNLNLKAFLECSNEVRDLISRLLVKNPKKRLC-----DIDCYNHPWV ..| .|.| |||.| .|..||. |.|....|.... . |.| .|||...| ..|.||| . .||| LMYEMLTGCPPFQGPNDNNRKEIMKRIQKGKFSLTMPNWQYLSQEAKDLIRKMLHRDPHKRLGCGPQDAEEIKQHPWF |
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| Kinase | 10195.AA | TyrKc | 51-303 | 24 | 3.8e-31 | 110.73 | SMART | 1-280 (280) | Show / Hide |
Range on Protein: 51-303 Range on HMM: 1-280/280 Sequence Identity: 24% (71 aa) YKFLKELGSGAFGVVFLATHRITGDERAVKAVAKDRLSDKQQFQDEINILKEL--DHPNIIKLYEVYESE-------STIYLVTEYCEGGELFQYVVQNK ...|.||.||||.|...| . . ||| . .| .. | .|..|...| .||||..|| | .. ...|.||...| | .| .. ITLGKKLGEGAFGEVYKGTWK---IQVAVKMLKEDA---REDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPHGDLKDYLRKHR R-LQEKDAALIMRQLFSAVSYIHDNGVIHRDLKPENFLLKKKSDPTTIKMIDFGISKKFKKG-------EVLRQQS--GTP-----YYIAPEVI-EGQYS . |. || .. | . .|.|....||||| | |.... |.| ||| |.. . . .. |... |. |||.| .| .. PKLCMKDLLSFCWQIACGMEYLHSKNCIHRDLAARNCLVGENH---TVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGKTMLPIRWMAPECINYGKFT EQVDNWALGVILY-ILLSGTPPFYG-----KNAQEIFYSIRKCNYNLNLKA-----FLECSNEVRDLISRLLVKNPKKRLCDIDCYNHP .. | |. || .. |. | .| .| ...||.. ... .. . | .|. |. ..... .|..| . ... TKSDVWSFGVCMWEIFTYGQQPYPGMIQQMMSNQEVIEYVKQGYRMPQPPNDYPMSFVCCPDEMYQIMKQCWHEDPEDRPTFSEIHECF |
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| Kinase | 10195.AA | Pkinase_Tyr | 51-172 | 31 | 1.6e-27 | 93.84 | Pfam | 1-137 (270) | Show / Hide |
Range on Protein: 51-172 Range on HMM: 1-137/270 Sequence Identity: 31% (44 aa) YKFLKELGSGAFGVVFLATHRITGDER-----AVKAVAKDRLSDK----QQFQDEINILKEL-DHPNIIKLYEVYE-SEST--IYLVTEYCEGGELFQYV .|.|.||.||||.|...| . .. ||| . |. ... . | |..|.|.| .||||..|| | . ||.|.||...| | | ITFGKKLGEGAFGEVYKGTWKG-DPDNTKIPVAVKML-KEGAMHEQNCREDFMREAKIMKQLGHHPNIVRLYGVCTDQGEPNQIYIVMEYMPHGDLLDYL VQ----NKRLQEKDAALIMRQLFSAVSYIHDNGVIHRDL . ...| || . .| .. .| .... ||||| RKHREDKQPLTMKDLLQMCWQIAKGMEYLESKNCIHRDL |
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| EFh | 10195.AA | EFh | 354-382 | 34 | 4.5e-07 | 30.73 | SMART | 1-29 (29) | Show / Hide |
Range on Protein: 354-382 Range on HMM: 1-29/29 Sequence Identity: 34% (10 aa) VLKQIFVSMDKDGNGRISLDELKGGLQLF .|..| .||||.|.|...|.| ... . EFKEMFRMFDKDGDGYIDFEEFKDMMKSL |
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| Efhand | 10195.AA | efhand | 354-382 | 34 | 6.6e-07 | 29.7 | Pfam | 1-29 (29) | Show / Hide |
Range on Protein: 354-382 Range on HMM: 1-29/29 Sequence Identity: 34% (10 aa) VLKQIFVSMDKDGNGRISLDELKGGLQLF ||..| .||||.|.|...|.. ... . ELKEMFKEFDKDGDGYIDFEEFCEMMKKL |
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| Efhand | 10195.AA | efhand | 394-422 | 34 | 2e-06 | 28.16 | Pfam | 1-29 (29) | Show / Hide |
Range on Protein: 394-422 Range on HMM: 1-29/29 Sequence Identity: 34% (10 aa) EVKQIFQAMDFDNSGQIDYSEFIATFLAN |.|..|. .| |..|.||. ||.. . . ELKEMFKEFDKDGDGYIDFEEFCEMMKKL |
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| EFh | 10195.AA | EFh | 394-422 | 34 | 1.7e-05 | 25.53 | SMART | 1-29 (29) | Show / Hide |
Range on Protein: 394-422 Range on HMM: 1-29/29 Sequence Identity: 34% (10 aa) EVKQIFQAMDFDNSGQIDYSEFIATFLAN |.|..|. .| |..|.||. ||.. . . EFKEMFRMFDKDGDGYIDFEEFKDMMKSL |
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| EFh | 10195.AA | EFh | 430-458 | 27 | 4e-06 | 27.66 | SMART | 1-29 (29) | Show / Hide |
Range on Protein: 430-458 Range on HMM: 1-29/29 Sequence Identity: 27% (8 aa) AITQAFLKIDKNNDGKITRQELQDILGTD . ..| ..||..||.|. .|..|.. . EFKEMFRMFDKDGDGYIDFEEFKDMMKSL |
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| Efhand | 10195.AA | efhand | 430-458 | 24 | 4e-06 | 26.89 | Pfam | 1-29 (29) | Show / Hide |
Range on Protein: 430-458 Range on HMM: 1-29/29 Sequence Identity: 24% (7 aa) AITQAFLKIDKNNDGKITRQELQDILGTD . ..| ..||..||.|...|..... . ELKEMFKEFDKDGDGYIDFEEFCEMMKKL |
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| EFh | 10195.AA | EFh | 466-494 | 37 | 1.7e-09 | 38.75 | SMART | 1-29 (29) | Show / Hide |
Range on Protein: 466-494 Range on HMM: 1-29/29 Sequence Identity: 37% (11 aa) DIDELIKEADTNGDGEIDFTEFLTMLREK ...|.....|..|||.||| ||..|.... EFKEMFRMFDKDGDGYIDFEEFKDMMKSL |
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| Efhand | 10195.AA | efhand | 466-494 | 44 | 1.1e-08 | 36.16 | Pfam | 1-29 (29) | Show / Hide |
Range on Protein: 466-494 Range on HMM: 1-29/29 Sequence Identity: 44% (13 aa) DIDELIKEADTNGDGEIDFTEFLTMLREK ...|..||.|..|||.||| ||..|.... ELKEMFKEFDKDGDGYIDFEEFCEMMKKL |
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