Gene 11510 (Tetrahymena)

11510

Species: Tetrahymena
Alias: 1.m00558, PreTt11510, TTHERM_00000020, 11510, 947
External Links: Tetrahymena Genome Database (TGD)
Annotation:

Classification

Group: Other
Family: Ciliate-E2
Subfamily: Ciliate-E2a

Sequence

Name Sequence Type Origin Length Description Download
11510.AA Protein None 494 None Fasta, JSON
11510.kin_dom Protein Kinase Domain None 261 None Fasta, JSON
11510.NA RNA None 1485 None Fasta, JSON

Protein domain

Protein domains of 11510.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Kinase 11510.AA Ciliate-E2a 121-381 43 5.9e-158 468.5 In-house 1-275 (275) Show / Hide 
Range on Protein: 121-381
Range on HMM: 1-275/275
Sequence Identity: 43% (119 aa)

YDIIDLIGNGTYSQVSLARHKVTGKKFAVKNISKNRVNSSLQNKRELMNEINLLRRLEHKNILKGVEYFETDNAYKIVLEYYSGKTLECRLQQIKSIKLA
|..|..||.|.. .| ||.|| |||.||.|...| . . . ..|...|||||..|.| |.||.|  |..|..| |..|.||..|..|.....| |...  
YKFIKKIGKGNFGSVYLAQHKQTGKQFAMKKFIK-KMYQQKKGKEYFMNEINIMRQLDHPNIIKLYEVYEDENNYYLVMEYCEGGELYDKIKQCKRFFEE

--DACFIMQQIL-QGLQYIHSLNIMHRDLKPENILLK--DPNS---FEIVIADIGFAQDL--YQD-FVLPKCGSPGYIAPEVLNSRD---GKDCGVKTDM
  ..| ||||.| |||.|.|..|||||||||||||.|  ..||   ..|.|.| |.|..   ..  .. .|||.|||.||||||...   .|....| ||
IQEICDIMQQLLWQGLHYMHQRNIMHRDLKPENILFKNCSKNSIQNSDIKIIDFGLATFIDKDEKKYMFQKCGTPGYVAPEVLNNKEVLKHKQYDTKCDM

FSCGLLFYRLVAGKPLFSGKTVEQTLIENKKFKIDLSSSQ-IAQYPLQIQKIIKGMLQINPVKRISAEQALLSGFY
.|||. ||.|. |||.| |||....|..||| |||.....   ..... . ..|.||. .| |||.|.||| . ..
WSCGVIFYILLCGKPPFKGKTYNEILQQNKKCKIDFNCPECWEKCSKECKDLMKKMLEKDPKKRITAQQALNHPWF
Kinase 11510.AA Ciliate-E2 121-381 25 8.7e-85 287.98 In-house 1-365 (365) Show / Hide 
Range on Protein: 121-381
Range on HMM: 1-365/365
Sequence Identity: 25% (96 aa)

YDIIDLIGNGTYSQVSLARH-----------------------KVTGKKFAVKNISKNRVNSSLQNKRELM---------NEINLLRRLEHKNILKGVEY
|..| .||.|....| ....                       ||..|..|.|...|| ... .| .....         || |.|..| |.||.| .|.
YKFIKKIGQGNFGSVYKCKVWKVQKQFAIKIIDQKQQRQQMQEKVKIKIYAMKIMKKNQIEQIKQEIHIMREINCFYKKINEKNILEQLNHPNIIKMYEC

FE--TDNAYKIVLEYYSGKTLECRLQQI-----------KSIKLADACFIMQQILQ---------------GLQYIHSLN-IMHRDLKPENILLKDPNSF
|.  .|| . .|.||..|..|. ....            |....  ...||.||||               .|.|.|| | |.|||.||||||.      
FQEKDDNNIYLVMEYCQGGDLFDYIKNNKKKRNHEIEKDKYFTEKEIKYIMKQILQGFKTKAEFYIACIILALEYLHSKNNIIHRDIKPENILF------

EIVIADIGFAQDLYQD------FVLPK---------------------------CGSPGYIAPEVLNSRD------GKDCGVKTDMFSCGLLFYRLVAGK
 | |.| |..... .|      ... |                           ||.||| |||.||. .      .|. . | |..|.| ..|... ||
-IKIIDFGLSKKYDDDNQNRTHKQQCKWYMFKNDTSRTPGYMDQIIQQNMFNTICGTPGYMAPEILNGKKYDNQQKQKGYDYKCDIWSLGVILYEMLFGK

PLFSGKTVEQTLIENKKFKIDLSSS--------------QIAQYPLQIQKIIKG----MLQINPVKRIS-AEQALLSGFY
| |        ....|. |||...                  . ... . .||     ||| .| |||. .||.|   . 
PPF--------QQQIKQCKIDFPCPEWQKDTQCIQCKWKSWKKWSQECKDLIKKFGKRMLQKDPEKRITGWEQILNHPWF
Kinase 11510.AA CAMK 126-381 21 1.2e-74 239.78 In-house 1-425 (425) Show / Hide 
Range on Protein: 126-381
Range on HMM: 1-425/425
Sequence Identity: 21% (91 aa)

LIGNGTYSQVSLARHKVTG------------KKFAVKNISKNRVNS------------------------SLQNKRELMNEINLLRR-------LEHKNI
 .| |....| |..|| |.            .|.|.| |.|... .                        . ........||.....       | |.||
TLGRGSFGKVKLCIHKNTTGKERVHHIYTNGQKVAIKIIDKKKLKDKQNQDYSNCYKIDKSKCKHRYCWRRPKDRKNVRREIEIMKKLQGIGNKLDHPNI

LKGVEYFE------------TDNA--------YKIVL---EYYSGKTLECR-LQQIKS------------------IKLADACFIMQQILQGLQYIHSLN
.|  |..|            | .         . .|.   || ||  | .. .. |..                  .. ..|.....||.....|.||.|
IKLYEVYEDPHYFKNTNDYET-SKQVFTKDKHMYMVMEIMEYCSGGELFDDLFDYIVEHGCYGEEFDQFDIVERGRFTEREARRYFRQICSAVHYCHSHN

IMHRDLKPENILLKDPNS---------------FEIVIADIGFAQDL-------------------------YQDFVLPKCGSPGYIA-PEVLNSRD---
|.||||||||||| | |.               . | |.| |||. .                         . .     ||.|.|.| |||||.     
IVHRDLKPENILLDDNNDDSDPVEHDEIFDWNNNNIKIIDFGFANKFDPGENNFMCSDYKGGEMHNQWTTPTEGQKMKTFCGTPEYMAAPEVLNGKGHCN

--------GKDCGVKTDMFSCGLLFYRLVAGKPLFSGK-------------TVEQTLIENKKFKIDLSSSQIAQ--------------------YPLQIQ
         . .| |.|| ||| . | .. |.| | |.             . ....   .| | |  ....                         . .
MQNATDEEKPYYGPKCDMWSCGVILYIMLCGYPPFYGDCDNEICEDEWIGMNDYELFEKIMKGKYDFPPPYFSPISCNYGPEWWDDISDEFHHFVSQECK

KIIKGMLQINPVKRISAEQALLSGFY
  |..||| .| ||...||.|   ..
DLIRKMLQVDPEKRMTIEQCLNHPWM
Kinase 11510.AA S_TKc 121-381 29 1.4e-72 248.4 SMART 1-231 (231) Show / Hide 
Range on Protein: 121-381
Range on HMM: 1-231/231
Sequence Identity: 29% (83 aa)

YDIIDLIGNGTYSQVSLARHKVTGKKFAVKNISKNRVNSSLQNKRELMNEINLLRRLEHKNILKGVEYFETDNAYKIVLEYYSG--KTLECRLQQIKS--
|.|...|| |....| ..||| ||...|.| |.           . ...||..|..  |.|| |  ..|.. . . .|.|| .|   .|  .... ..  
YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK-----------EHIRREIQILKK-HHPNIVKLYDVFQD-DHLYMVMEYCDGDLGDLFDYIKKRGRHG

----IKLADACFIMQQILQGLQYIHSLNIMHRDLKPENILLKDPNSFEIVIADIGFAQDLYQDFVLPKCGSPGYIAPEVLNSRDGKDCGV-KTDMFSCGL
    .   .|.|.|.||...|.|.||..|.||||||||||| .    .| |.| |.|  |        ||.| |.|||||        |  | |. ||| 
LRFPFPE-HARFYMYQICCALEYCHSHGIIHRDLKPENILLDE----HIKICDFGLARQL-----TTFCGTPWYMAPEVL------GYGKCKCDWWSCGC

LFYRLVAGKPLFSGKTVEQTLIENKKFKIDLSSSQIAQYPLQIQKIIKGMLQINPVKRISAEQALL-------SGFY
..| ...|.|.|.    .|..... .             . .   .|...|| .| ||..| .||          . 
ILYEMLCGYPPFP---QMQMMFKKIG-------------SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF
Kinase 11510.AA Pkinase 121-381 29 1.6e-64 225.46 Pfam 1-293 (293) Show / Hide 
Range on Protein: 121-381
Range on HMM: 1-293/293
Sequence Identity: 29% (89 aa)

YDIIDLIGNGTYSQVSLARHKVTGKKFAVKNISKNRVNSSLQNKRELMNEINLLRRLEHKNILKGVEYFETDNAYKIVLEYYSGK----TLECRLQ--QI
| |.  || |....| ...|| |||..||| |.| . .|. .  . . .|| ...|| |.||..  ..||... . .|.||  |      |  ...  . 
YHIGRKIGSGSFGCVYKCHHKGTGKIVAVKIIKKRHEKSWKDQTHRRLSEIQIMKRLNHPNIVRLYDWFEDKDHIYMVMEYCEGGLYVMDLFDYISTWRH

KSI--KLADACFIMQQILQGLQYIHSLNIMHRDLKPENILLKDPNSFE---IVIADIGFAQ---DLYQDFVLPKCGSPGYIAPEVLNSRDGKDCGVKTDM
...     ...|.| |||.||.|.|| .|.||||||||||..  |      . |.| |.|       .      ||.|.|.||||..  .|.. | | ||
GCFYFSEWECKFYMYQILRGLEYCHSMGIIHRDLKPENILID-NNGHIDACVKICDFGLAKQFDY-NNS-MTTFCGTPWYMAPEVIR--GGQYYGPKVDM

FSCGLLFYRLVAGKPLFSGK------TVEQTLIENKKFKIDLSSSQIAQYP-----------------LQIQKIIKGMLQINPVKRISAEQALLSGFY
.|||...| .. |.|.|.|.      .  | . .... ... ....    .                    ...||..|. .| ||..|||.| . . 
WSCGCILYEMLCGRPPFPGHCWHDNHDQMQMICRIMGPPLHFDWPWWCSISYFFFRHWHFHWTFHNWSEECKDFIKWCLCKDPKKRPTAEQILQHPWF
Kinase 11510.AA CAMKL 121-381 28 3.1e-60 190.85 In-house 1-297 (297) Show / Hide 
Range on Protein: 121-381
Range on HMM: 1-297/297
Sequence Identity: 28% (87 aa)

YDIIDLIGNGTYSQVSLARH-KVTGKKFAVKNISKNRVNSSLQNKRE-----------LMNEINLLRRLE---HKNILKGVEYFETDNA------YKIVL
|.|.. .| |....| ||.| . ||.| |.| | |.. .   ..|.            .  ||.....|    |.|| |  | .||..       . .|.
YRIGKTLGKGSFGKVKLATHIRTTGEKVAIKIIDKKKIWNDPWMKKNKCGQKHESDMRIRREIQIMKMLNIGKHPNIIKLYEVIETPEHDIETKKIYLVM

EYYSGKT--LECRLQQI----KSIKLADACFIMQQILQGLQYIHSLNIMHRDLKPENILLKDPNSFEIVIADIGFA----------QDLYQDFVLPKCGS
|| ||    |  ....     ....  .|... .||. ...|.||..| |||.||||||| . ..  | |.| ||.           ..   |    |||
EYCSGGEMDLFDYIVKHGHRRGRMPEHEARRYFRQIVSAVNYCHSHGIVHRDIKPENILLDENGNNNIKIIDFGFSNMYRPCIFGPGQKLKTF----CGS

PGYIAPEVLNSRDGKDCGVKTDMFSCGLLFYRLVAGKPLFSGKTV---EQTLIENKKFKIDLSSSQI-AQYPL-QIQKIIKGMLQINPVKRISAEQALLS
| | |||....   . .| |.|. ||| . | .| |.  | . |.    .. | ... ||     ..   | . . . .|..||| || ||....| .  
PPYMAPEIFQGNNKPYDGPKVDIWSCGVILYAMVCGYLPFDDDTYNKQGKDNI-YLYWKIMCG-YYPPIWYHVSDCRDLIRKMLQVNPEKRPTIHQIMNH

GFY
 ..
PWM
Kinase 11510.AA Ciliate-E2-Unclassified 121-381 24 3.5e-59 202.92 In-house 1-352 (352) Show / Hide 
Range on Protein: 121-381
Range on HMM: 1-352/352
Sequence Identity: 24% (87 aa)

YDIIDLIGNGTYSQVSLARHKVTGKKFAVKNISKNRVNSSLQ--------NKRELMNEIN-------------LLRRLEHKNILKGVEYFETDNAYKIVL
| ||  ||.| ...| ...|| .....| | ..|.......|        |. . ||...             .|. . | .|.| ...|....   ||.
YKIIKQIGQGGFGKVYKCQHKKQKQYYAMKYMKKIQIYKQKQIMNKDEIMNEMKEMNNKKKYHQRKYNKIMQQILLNHPHPFIVKMFYCFQDKQNIYIVM

EYYSGKTLECRLQQIKS-----------------IKLADAC-----FIMQQILQGLQYIHSLN-IMHRDLKPENILLKDPNS-FEIVIADIGFAQDLY--
||  |..|.  ... |.                 .    |.     |.. ||||||.|.|. | | |||.||||||... .. ..| |.| |..  .   
EYCEGGDLWQYIKKRKKQKQKGNDLFHNMKQRKIFTEQQAKYKKAKFYFAQILQGLEYLHHKNNIIHRDIKPENILFDNNGKNYYIKIIDFGISKKYQQN

---------------QDFVLPKCGSPGYI----APEVLNS--RDGKDCGVKTDMFSCGLLFYRLVAGKPLFSGKTVEQ---------------TLIENK-
               |.    .||.|.|.    ||||| .   |..    | |..|.| ..| .. |.. |.... ||                |..|. 
NNCDTNQQQKMQIWKQQMMWTFCGTPNYMPQYTAPEVLQGQNYDHSKA-YKCDIWSLGVILYEMLFGYYPFYDNNCEQHQQLITQWINNAYRKQLYQNIK

KFKIDLSSSQI----AQYPLQIQKIIK----GMLQINPVKRISAEQALLSGFY
. .|. ...       . . . . .|.     ||. || |||..||.|   . 
QKNIQFPKFPWQQIPKHWSPEAKDFINDLLQKMLKKNPNKRITFEQILNHPWF
Kinase 11510.AA ULK 121-371 25 2.8e-56 193.27 In-house 1-314 (324) Show / Hide 
Range on Protein: 121-371
Range on HMM: 1-314/324
Sequence Identity: 25% (79 aa)

YDIIDLIGNGTYS-QVSLARHKVT---GKKFAVKNISKNRVNSSLQN------KRELMNEINLLRRLE---HKN--ILKGVEYFETD--NAYKIVLEYYS
| ... .| |..  .|  .|.| |   ....|.| |.|.  | . ..      .  |.|||.... |    |.|  | |  ..|||.  | . |..||  
YCLNHCLGKGSFGVKVYKGRNKKTNTQNQYVACKMIDKKKMNKKKNEQEGQYMWQLLKNEIQIMKKLKELKHPNHHIVKLYDWFETSNHNNIYIIMEYCN

GKTLECRLQQIKS---------IKLADACFIMQQILQGLQYIHSLNIMHRDLKPENILLKDPN----------SFEIVIADIGFAQDLYQD-FVLPKC--
| .||  ... |          .    |  ...||..|....|. ||.|||.||.|||.....          .  . ||| |||. .  . .   .|  
GGDLEQYIKKNKKLPETEEKKRLSEQEAIQFFKQICNGFKELHKHNIIHRDIKPQNILIHNGQPKTDSKKVHPNGVLKIADFGFAKHVDNNNMEQQMCQT

--------GSPGYIAPEVLNSR-DGKDCG-VKTDMFSCGLLFYRLVAGKPLFSGKTVEQTL----------------IENKKFKIDLSSSQIAQYPLQIQ
        |.| | ||..|...  .|. .  |.|..| | .|| .. ||. |..   ...                 |.|....... . .. .   ...
CVNEKRIKGTPLYMAPQILQGQGEQKPYYDYKCDIWSLGCIFYEMLYGKYPFFSW-FNDQYLYIQKLINNGKEQQIYIKNQPIQFPKPP-KDPKISPECK

KIIKGMLQINPVKRIS
 .|..|||... .|||
DLIRRMLQYDEKDRIS
Kinase 11510.AA ULK 121-371 26 6.2e-53 182.18 In-house 1-319 (329) Show / Hide 
Range on Protein: 121-371
Range on HMM: 1-319/329
Sequence Identity: 26% (86 aa)

YDIIDLIGNGTYSQVSLARHKVT----GKKFAVKNISKNRVNSSLQN------KRELMNEINLLRRLE----HKN----ILKGVEYFETD--NAYKIVLE
| ... .| |.. .|  .|.| |    ..|.|.| |.|.  | ....      .  |.||| ....|     |||    | |  ..|||.  | . |..|
YCLNHCLGKGSFGKVYKGRNKKTKDYVNEKVACKMIDKQKMNQKNNEQEGQYMWQLLKNEIKIMKKLKSPNRHKNHHPNIVKLYDWFETSNHNNIYIIME

YYSGKTLECRLQQIKSIKLAD----------ACFIMQQILQGLQYIHSLNIMHRDLKPENILLKDPN----------SFEIVIADIGFAQDLYQD-----
|  | .||  ... |   .            |  ...|||.|....|. ||.|||.||.|||.....          .  . ||| |||. .  |     
YCNGGDLEQYIKKNKKLPEDTEEKKRLSEQEAIQFFKQILNGFKELHKHNIIHRDIKPQNILIHNGQPKTDSKKVHPNGVLKIADFGFAKHVDNDNMEQQ

-FVLPK-----CGSPGYIAPEVLNSR-DGKDCG-VKTDMFSCGLLFYRLVAGKPLFSGKTVEQTL---IENKKFK-------IDLSSSQ------IAQYP
 ..  .     ||.| | ||..|...  .|. .  |.|..| | .|| .. ||| |..   ...    |.. . .       |.    |      . |  
MMMTCVNEKRLCGTPLYMAPQILQGQGEQKPYYDYKCDIWSLGCIFYEMLYGKPPFYAW-FNDQYLQIIQKLINNPPPWPQQIKKQPLQFPKDGNDPQIS

LQIQKIIKGMLQINPVKRIS
 ... .|..|||... .|||
PECKDLIRRMLQYDEKDRIS
Kinase 11510.AA CAMK-Unique 121-381 20 7.8e-47 152.52 In-house 1-363 (363) Show / Hide 
Range on Protein: 121-381
Range on HMM: 1-363/363
Sequence Identity: 20% (74 aa)

YDIIDLIGNGTYSQVSLARHKVTGKKFAVKNISKNRVNSSLQNK----------------RELMNEINLLRRLEHKNILKGVEY----FETDN-------
|. . .||.|... |  .  ..||||.|.| . | .. .. |                   .|..|....... | ||.| ...    |....       
YKMHRIIGHGNFGHVYECMDRETGKKWACKMVKKQTHGNKKQKQQRNFDLRYKITEKRRDMKLKREHQIWKMVDHPNIIKLYDWNNPIFCDRKYPLCDLI

--------AYKIVLEYYSGKTLECRLQQI-------------------KSIKLA---DACFIMQQILQGLQYIHSLNIMHRDLKPENILLKDP-------
        .. ||.||  |..|   .|.                    . .  .   |.|||||..|. . | ||..| |||||.|||... .       
IKTPRALPYMYIVMEYCQGGDLFDWIQKWDEFYFNFIIKFDFNILKRCQGHFSERCWDTCFIMQCLLSAVAYMHSQDIVHRDLKLENIMVCYSFKDNNHH

-------NSFEIVIADIGFAQDLYQDFVLP----KCGSPGYIAP--------------EVLN-SRDGKDCGVKTDMFSCGLLFYRLVAGKPLFSGKTVEQ
       .   |...| | . .. .  . .     ||.| |.||              ||.| .. .  |.   |  |.| . | .  |.| | . . . 
RDFPYDWSNWHIKLCDFGLCCHYNHNKMCHMMQTMCGTPCYMAPEIVFCKNYQEMTRDEVINMQCYDQQCSPASDIWSLGVIMYYMLCGCPPFDCECEDR

-------TLIEN-KKFKI-DLSSSQIAQ---YPLQIQKIIKGMLQINPVKRISAEQALLSGFY
        ..|. .| .. ......         .   ..|. ... |..|.||...| . . 
DYENHDKEIFECICKGDYCNFDWKMWHGPDYISQEAKDFVKCCMTVDPDHRWSAKELLEHQWI
Kinase 11510.AA STE 121-381 19 1.2e-43 151.37 In-house 1-359 (359) Show / Hide 
Range on Protein: 121-381
Range on HMM: 1-359/359
Sequence Identity: 19% (70 aa)

YDIIDLIGNGTYSQVSLARHKV---------------TGKKFAVKNISKNRVN-------------SSLQNKRELMNEINLLRRLE--HKNILKGVEYFE
...|. ||.|.. .| .|...                ||. .|.| ..... |             .  ... ....||......   |.|| |   ...
WEGIEKIGKGAFGTVYKAMNHKNCNIHKTGEVENNGETGEIMAIKQMNLENCNNKDENQENQELENKNHEEMQQILKEIKIMKKCNHMHPNIVKYYGCYF

TD-------NAYKIVLEYYSGKTLECRLQQIKSIK--------------LADACFIMQQILQG-LQYIHSLNIMHRDLKPENILLKDPNSFEIVIADIGF
 .       .   |..|| .| .|.  ... ....                  ..| .|||.| |.|.||..|.|||.|| ||||       . ..| |.
KEGHNHKNDDELWICMEYMDGGSLDDIIKHKYGCGKPLNHNRQHQHRFPESQIAYICRQILKGLLYYLHSHHIIHRDIKPANILL-------VKLCDFGV

AQDLYQD------------------FVLPKCGSPGYIAPEVLNSRD---GKDCGVKTDMFSCGLLFYRLVAGKPLF---SGKTVEQTLIENK--------
.  | ..                       .|.| . ||||.. ..    |....| |. | |..   .. ||| .   .   .    . |.        
CGQLTDSMANIQSNNIIDCIETMQQKRNTFVGTP-WMAPEVIQQNGQGRDKGYDTKCDIWSLGCTIIEMATGKPPWHDMHPMRAMFMIPFNYHMQQQFEQ

-----KFKIDLSSSQI---------------AQYPLQIQKIIKGMLQINPVKRISAEQALL--SGFY
     .    | .                   ..    .  |.  ||..| || .|.| |     | 
LCIVNGPPPPLPDHLSQNEMISYGGSGTTYPHKWSPEFKDFINKCLQKDPNKRPTASQLLKSEHPFI
Kinase 11510.AA CAMK1 221-334 42 8.5e-36 101.5 In-house 109-227 (276) Show / Hide 
Range on Protein: 221-334
Range on HMM: 109-227/276
Sequence Identity: 42% (50 aa)

DACFIMQQILQGLQYIHSLNIMHRDLKPENILLKDP-NSFEIV--IADIGFAQDLYQDF-VLPK-CGSPGYIAPEVLNSRDGKDCGVKTDMFSCGLLFYR
||. ||.|||. ..|.||..|.||||||||.|..|. . ..|.  ||| | .. . .|  .. . ||.|||.|||||.    |  . . ||.|.|  .| 
DARHIMKQILSAVEYMHSKGIVHRDLKPENLLYYDKDEDSKIKRSIADFGLSKIFDHDENLMKTACGTPGYVAPEVLECKKDKPYDKACDMWSIGVITYI

LVAGKPLFSGKTVEQTLIE
|  | | | ...|...| |
LLCGYPPFYDENVDNELFE
Kinase 11510.AA CAMK1 121-204 33 1.6e-26 74.08 In-house 1-92 (276) Show / Hide 
Range on Protein: 121-204
Range on HMM: 1-92/276
Sequence Identity: 33% (32 aa)

YDIIDLIGNGTYSQVSLARHKVT---GKKFAVKNISKNRVNSSLQNKRE-----LMNEINLLR---RLEHKNILKGVEYFETDNAYKIVLEYYSG
| ... ||.|. |.| |. || |   ||..|.| |.|   ......|..     |.|||. ..   .. | || |  |..|.|| . .|.|. .|
YEFGKEIGRGAFSEVYLCTHKETQTNGKQYAIKCIDK---KKFMKKKDMQKQEALENEIEIMKKVSKIDHPNIIKFYEWYESDNHFYLVMELVTG
Kinase 11510.AA TyrKc 121-380 20 1.9e-13 -5.39 SMART 1-280 (280) Show / Hide 
Range on Protein: 121-380
Range on HMM: 1-280/280
Sequence Identity: 20% (60 aa)

YDIIDLIGNGTYSQVSLARHKVTGKKFAVKNISKNRVNSSLQNKRELMNEINLLRRL--EHKNILKGVEYFETD-------NAYKIVLEYYSGKTLECRL
   .. .|.| . .| ... |    . ||| . ..        ....|.|......|  .|.||.. . .  ..         . ||.|| ..  |  .|
ITLGKKLGEGAFGEVYKGTWK---IQVAVKMLKEDA-------REDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPHGDLKDYL

QQIKS-IKLADACFIMQQILQGLQYIHSLNIMHRDLKPENILLKDPNSFEIVIADIGFAQDLYQD--------FVLPKC--GSPG-----YIAPEVLNSR
.  .  ....| . .. || .| .|.|| |. ||||   |.|.....   . |.| | . |.| |           .|   |. .       |||..  .
RKHRPKLCMKDLLSFCWQIACGMEYLHSKNCIHRDLAARNCLVGENH--TVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGKTMLPIRWMAPECI--N

DGKDCGVKTD----------MFSCGLLFYRLVAGKPLFSGKTVEQTLIENKKFKIDLS----SSQIAQYPLQIQKIIKGMLQINPVKRISAEQALLSGF
.|| .  |.|          .|. |   |  .. .   | . | . . . .  ..  .    |.     |  . .|.|   . .| .| . ..   . |
YGK-FTTKSDVWSFGVCMWEIFTYGQQPYPGMIQQ-MMSNQEVIEYVKQGYRMPQPPNDYPMSF--VCCPDEMYQIMKQCWHEDPEDRPTFSEI-HECF
Kinase 11510.AA Pkinase_Tyr 121-246 22 4.6e-07 24.55 Pfam 1-137 (270) Show / Hide 
Range on Protein: 121-246
Range on HMM: 1-137/270
Sequence Identity: 22% (32 aa)

YDIIDLIGNGTYSQVSLARHK----VTGKKFAVKNISKNRVNSSLQN--KRELMNEINLLRRL-EHKNILKGVEYFE-TDNA--YKIVLEYYSGKTLECR
  ..  .| | . .| ... |     |. . ||| . |.  ... ..  ....|.|..... |  |.||.. .      .    . ||.||  .  |   
ITFGKKLGEGAFGEVYKGTWKGDPDNTKIPVAVKML-KE--GAMHEQNCREDFMREAKIMKQLGHHPNIVRLYGVCTDQGEPNQIYIVMEYMPHGDLLDY

LQQ----IKSIKLADACFIMQQILQGLQYIHSLNIMHRDL
|..     ..... | . . .|| .|..| .| |. ||||
LRKHREDKQPLTMKDLLQMCWQIAKGMEYLESKNCIHRDL
Kinase 11510.AA CAMK1 358-376 52 9.9e-05 9.61 In-house 253-271 (276) Show / Hide 
Range on Protein: 358-376
Range on HMM: 253-271/276
Sequence Identity: 52% (10 aa)

IKGMLQINPVKRISAEQAL
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IKHMLEVDPKKRYTCEQCL