Gene 23204 (Tetrahymena)

23204

Species: Tetrahymena
Alias: 23204, TTHERM_00690080, 952, 3737.m00083, PreTt23204, 105.m00171
External Links: Tetrahymena Genome Database (TGD)
Annotation:

Classification

Group: Other
Family: Ciliate-E2
Subfamily: Ciliate-E2a

Sequence

Name Sequence Type Origin Length Description Download
23204.AA Protein None 932 None Fasta, JSON
23204.kin_dom Protein Kinase Domain None 236 None Fasta, JSON
23204.NA RNA None 2799 None Fasta, JSON

Protein domain

Protein domains of 23204.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
RNase_P_p30 23204.AA RNase_P_p30 45-196 30 2.9e-39 137.4 Pfam 1-156 (156) Show / Hide 
Range on Protein: 45-196
Range on HMM: 1-156/156
Sequence Identity: 30% (48 aa)

LKRITLEINDGKYLPQ--LKSNTALAT-YDIIAIKTRNEKVFHSLCIDYDDYDILCFDMSERLPFIPKRGWIQEAVRKGISFEICYSEAI--EDPAKKRT
..|.|....| |   .  ...  ...  |||.|..  .||.|.  | . |  ||...|...||||. |.  .. ||..|. |||||| .|   |. ..| 
YRRVTIVCSDPK-SQHCWRQRVSKFRQKYDIVAVRPGDEKAFRYACENMD-VDIISHDWTQRLPFYFKHKMAKMAVERGVAFEICYSPLITRRDGYARRN

VLANCINIVKMTKG--KNIIFSSSCSSDFDHRSPFDIIMLGTLIGLTRDQTHDALKKFP
.. |. .... ...  ..||.||...| .. |.|.|.| ||.|.|.. ..  .|.  ..
FISNARQLIRWCRKYDRPIIISSGARSPWELRNPYDVINLGHLWGMEEEEAKEAMS-TN
Kinase 23204.AA Ciliate-E2a 442-677 41 4.3e-140 415.03 In-house 1-275 (275) Show / Hide 
Range on Protein: 442-677
Range on HMM: 1-275/275
Sequence Identity: 41% (113 aa)

YEFIKQIGQGQFGSVFLAKRRKQPFDEVAIKIINLNQIKKIPLQYIKREVQISKSLDHPNIIKFQETYIDKKNIYIVMEYCTGGNLS-----QK-QFSE-
|.|||.||.|.||||.||............|.|. ....|.. .|...|..|...||||||||. |.|.|..|.|.||||| || |      .| .|.| 
YKFIKKIGKGNFGSVYLAQHKQTGKQFAMKKFIKKMYQQKKGKEYFMNEINIMRQLDHPNIIKLYEVYEDENNYYLVMEYCEGGELYDKIKQCKRFFEEI

QEVLNIMKKLL---------------DLKLENILYE---RDS-PDSEIKIIDFGLSKQVPKEQKARRHSIVGSETYMAPEVLSSKN------YDKSCDVW
||.  ||..||               |||.||||..    .| ..|.||||||||.....| .| ......|.  |.||||| .|       ||..||.|
QEICDIMQQLLWQGLHYMHQRNIMHRDLKPENILFKNCSKNSIQNSDIKIIDFGLATFIDKDEKKYMFQKCGTPGYVAPEVLNNKEVLKHKQYDTKCDMW

SLGVIMYRLLSGELPFKQ------RQQILDGLLIFKSPI-WSSVSRDAFDLLKKMVNVYPQYRITIDQALKHSWF
|.|||.|.||.|..|||.       ||. .  . | .|. |. .| ...||.|||....|..|||. |||.| ||
SCGVIFYILLCGKPPFKGKTYNEILQQNKKCKIDFNCPECWEKCSKECKDLMKKMLEKDPKKRITAQQALNHPWF
Kinase 23204.AA Ciliate-E2 442-677 30 1.8e-95 323.51 In-house 1-365 (365) Show / Hide 
Range on Protein: 442-677
Range on HMM: 1-365/365
Sequence Identity: 30% (114 aa)

YEFIKQIGQGQFGSVFLAKRRKQPFDE-----------------VAIKIINLNQIKKIPLQYIKREVQISK----------------SLDHPNIIKFQET
|.|||.||||.||||...|..|.. ..                 |.|||......||  ...||.| .| .                .|.||||||. |.
YKFIKKIGQGNFGSVYKCKVWKVQKQFAIKIIDQKQQRQQMQEKVKIKIYAMKIMKKNQIEQIKQEIHIMREINCFYKKINEKNILEQLNHPNIIKMYEC

YI--DKKNIYIVMEYCTGGNLSQ----------------KQFSEQEVLNIMKKLL------------------------------DLKLENILYERDSPD
..  |..|||.||||| ||.| .                |.|.|.|...|||..|                              |.|.||||.      
FQEKDDNNIYLVMEYCQGGDLFDYIKNNKKKRNHEIEKDKYFTEKEIKYIMKQILQGFKTKAEFYIACIILALEYLHSKNNIIHRDIKPENILF------

SEIKIIDFGLSKQVPKEQKARR------------------------------HSIVGSETYMAPEVLSSKN---------YDKSCDVWSLGVIMYRLLSG
  ||||||||||.. .... |.                              ..|.|.  |||||.|..|.         ||..||.||||||.|..|.|
--IKIIDFGLSKKYDDDNQNRTHKQQCKWYMFKNDTSRTPGYMDQIIQQNMFNTICGTPGYMAPEILNGKKYDNQQKQKGYDYKCDIWSLGVILYEMLFG

ELPFKQRQQILDGLLIFKSP--------------IWSSVSRDAFDLLKK----MVNVYPQYRIT-IDQALKHSWF
..||   |||... . | .|              .| ..| .. ||.||    | .. |. ||| ..|.|.| ||
KPPF--QQQIKQCKIDFPCPEWQKDTQCIQCKWKSWKKWSQECKDLIKKFGKRMLQKDPEKRITGWEQILNHPWF
Kinase 23204.AA CAMK 447-677 22 3.7e-81 261.12 In-house 1-425 (425) Show / Hide 
Range on Protein: 447-677
Range on HMM: 1-425/425
Sequence Identity: 22% (97 aa)

QIGQGQFGSVFLAKRRKQPF-----------DEVAIKIINLNQIKKI--------------------------PLQYIKREVQISKS-------LDHPNI
..|.|.|| |.|..... .             .||||||. ...|.                            .. ..||..| |.       ||||||
TLGRGSFGKVKLCIHKNTTGKERVHHIYTNGQKVAIKIIDKKKLKDKQNQDYSNCYKIDKSKCKHRYCWRRPKDRKNVRREIEIMKKLQGIGNKLDHPNI

IKFQETYID-------------------KKNIYIVM---EYCTGGNL--S-------QKQ---------------FSEQEVLNIMKKLLD----------
||. |.| |                   .|..|.||   |||.|| |          ...               |.|.|.  ... ...          
IKLYEVYEDPHYFKNTNDYETSKQVFTKDKHMYMVMEIMEYCSGGELFDDLFDYIVEHGCYGEEFDQFDIVERGRFTEREARRYFRQICSAVHYCHSHNI

----LKLENILYERDSPDSE--------------IKIIDFGLSKQVPKEQKAR----------------------RHSIVGSETYMA-PEVLSSKN----
    ||.||||.  ...||.              |||||||....... .. .                       .  .|.  ||| ||||..|     
VHRDLKPENILLDDNNDDSDPVEHDEIFDWNNNNIKIIDFGFANKFDPGENNFMCSDYKGGEMHNQWTTPTEGQKMKTFCGTPEYMAAPEVLNGKGHCNM

----------YDKSCDVWSLGVIMYRLLSGELPFKQR-------------------QQILDGLLIFKSPI------------WSSVSRD--------AFD
          |...||.||.|||.| .|.|..||                      ..|. |   | .|             |...| .        . |
QNATDEEKPYYGPKCDMWSCGVILYIMLCGYPPFYGDCDNEICEDEWIGMNDYELFEKIMKGKYDFPPPYFSPISCNYGPEWWDDISDEFHHFVSQECKD

LLKKMVNVYPQYRITIDQALKHSWF
|..|| .| |. |.||.|.|.| |.
LIRKMLQVDPEKRMTIEQCLNHPWM
Kinase 23204.AA S_TKc 442-677 33 5.3e-75 256.39 SMART 1-231 (231) Show / Hide 
Range on Protein: 442-677
Range on HMM: 1-231/231
Sequence Identity: 33% (90 aa)

YEFIKQIGQGQFGSVFLAKRRKQPFDEVAIKIINLNQIKKIPLQYIKREVQISKSLDHPNIIKFQETYIDKKNIYIVMEYCTG--GNLSQ--KQ------
||....||.| ||.|.... .|    .||||||.         . |.||.|| |. .||||.|. ... | ...|.||||| |  |.| .  |.      
YEILRKIGKGAFGKVYKCRHKK-TGRIVAIKIIK---------EHIRREIQILKK-HHPNIVKLYDVFQD-DHLYMVMEYCDGDLGDLFDYIKKRGRHGL

---FSEQEVLNIMKKLL--------------DLKLENILYERDSPDSEIKIIDFGLSKQVPKEQKARRHSIVGSETYMAPEVLSSKNYDK-SCDVWSLGV
   |.| ..  .|. ..              ||| ||||  .     .|||.||||..|.        ....|.  |||||||    |.| .||.||.|.
RFPFPE-HARFYMYQICCALEYCHSHGIIHRDLKPENILLDE-----HIKICDFGLARQL--------TTFCGTPWYMAPEVL---GYGKCKCDWWSCGC

IMYRLLSGELPFKQRQQILDGLLIFKSPIWSSVSRDAFDLLKKMVNVYPQYRITIDQALK-------HSWF
|.| .|.|. ||       .  ..||       |..| |...|. .. |. |.|. .||.       | ||
ILYEMLCGYPPFP------QMQMMFKKIG----SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF
Kinase 23204.AA ULK 442-677 27 9.1e-66 224.8 In-house 1-324 (324) Show / Hide 
Range on Protein: 442-677
Range on HMM: 1-324/324
Sequence Identity: 27% (89 aa)

YEFIKQIGQGQFG-SVFLAKRRKQP--FDEVAIKIINLNQIKKIPLQ--------YIKREVQISKSLD---HPN--IIKFQETYIDK--KNIYIVMEYCT
|. ....|.|.||  |. ..  |.      ||.|.|......|....         .|.|.|| | |.   |||  |.|. . . ..  .||||.|||| 
YCLNHCLGKGSFGVKVYKGRNKKTNTQNQYVACKMIDKKKMNKKKNEQEGQYMWQLLKNEIQIMKKLKELKHPNHHIVKLYDWFETSNHNNIYIIMEYCN

GGNLS---QKQ-----------FSEQEVLNIMKKLL--------------DLKLENILYERDSP--DSE-------IKIIDFGLSKQVPK--EQKARRHS
||.|.   .|.           .||||.....| ..              |.|..|||   . |  ||.       .|| |||..|.| .  ...  ...
GGDLEQYIKKNKKLPETEEKKRLSEQEAIQFFKQICNGFKELHKHNIIHRDIKPQNILIHNGQPKTDSKKVHPNGVLKIADFGFAKHVDNNNMEQQMCQT

IV------GSETYMAPEVLS----SKNYD-KSCDVWSLGVIMYRLLSGELPF---KQRQQ----------------ILDGLLIFKSPI-WSSVSRDAFDL
.|      |.  ||||..|.     |.|. . ||.||||.|.| .| |. ||   .. |.                | .  . |..|.    .| .  ||
CVNEKRIKGTPLYMAPQILQGQGEQKPYYDYKCDIWSLGCIFYEMLYGKYPFFSWFNDQYLYIQKLINNGKEQQIYIKNQPIQFPKPPKDPKISPECKDL

LKKMVNVYPQYRITIDQALKHSWF
...|  . .  ||.... ..| ||
IRRMLQYDEKDRISWEEIFNHPWF
Kinase 23204.AA ULK 442-677 27 1e-65 224.65 In-house 1-329 (329) Show / Hide 
Range on Protein: 442-677
Range on HMM: 1-329/329
Sequence Identity: 27% (89 aa)

YEFIKQIGQGQFGSVFLAKRRKQP---FDEVAIKIINLNQIKKIP--------LQYIKREVQISKSLD--------HPNIIKFQETYIDK--KNIYIVME
|. ....|.|.|| |. ..  |.       ||.|.| ........        .| .|.|..| | |.        ||||.|. . . ..  .||||.||
YCLNHCLGKGSFGKVYKGRNKKTKDYVNEKVACKMIDKQKMNQKNNEQEGQYMWQLLKNEIKIMKKLKSPNRHKNHHPNIVKLYDWFETSNHNNIYIIME

YCTGGNLS---QKQ------------FSEQEVLNIMKKLL--------------DLKLENILYERDSP--DSE-------IKIIDFGLSKQVPKE--QKA
|| ||.|.   .|.            .||||.....| .|              |.|..|||   . |  ||.       .|| |||..|.| ..  ...
YCNGGDLEQYIKKNKKLPEDTEEKKRLSEQEAIQFFKQILNGFKELHKHNIIHRDIKPQNILIHNGQPKTDSKKVHPNGVLKIADFGFAKHVDNDNMEQQ

RRHSIV------GSETYMAPEVLS----SKNYD-KSCDVWSLGVIMYRLLSGELPFKQRQQILD-----GL---------LIFKSPIWSS-------VSR
  .. |      |.  ||||..|.     |.|. . ||.||||.|.| .| |. ||.   . ..      |         .| | |.          .| 
MMMTCVNEKRLCGTPLYMAPQILQGQGEQKPYYDYKCDIWSLGCIFYEMLYGKPPFYAWFNDQYLQIIQKLINNPPPWPQQIKKQPLQFPKDGNDPQISP

DAFDLLKKMVNVYPQYRITIDQALKHSWF
.  ||...|  . .  ||.... ..| ||
ECKDLIRRMLQYDEKDRISWEELFNHPWF
Kinase 23204.AA RSK 546-677 34 1.5e-50 174.29 In-house 129-278 (278) Show / Hide 
Range on Protein: 546-677
Range on HMM: 129-278/278
Sequence Identity: 34% (52 aa)

DLKLENILYERDSPD-SEIKIIDFGLSKQVPKEQKARRHSIVGSETYMAPEVLS---SKN-YDKSCDVWSLGVIMYRLLSGELPFKQ---------RQQI
|||.|||||. .| .  .||..|||..|| . ... . .. ...  |||||.|     .. .||.||.|||||.|| .|.| .||..          ..|
DLKPENILYDDES-NEGHIKLTDFGFCKQFRCDHNQWTMTFCYTIEYMAPEMLKRANQQGGHDKACDWWSLGVLMYEMLTGCPPFQGPNDNNRKEIMKRI

LDGLLIFKSPIWSSVSRDAFDLLKKMVNVYPQYRIT-----IDQALKHSWF
. | . ...|.|...|..| ||..||  . |. |..     ... ..|.||
QKGKFSLTMPNWQYLSQEAKDLIRKMLHRDPHKRLGCGPQDAEEIKQHPWF
Kinase 23204.AA CDPK 546-677 38 4.4e-47 142.56 In-house 128-271 (271) Show / Hide 
Range on Protein: 546-677
Range on HMM: 128-271/271
Sequence Identity: 38% (56 aa)

DLKLENILYERDSPDS----EIKIIDFGLSKQVPKE---QKARRHSIVGSETYMAPEVLSSKNYDKSCDVWSLGVIMYRLLSGELPFKQR------QQIL
||| ||||.. ...||    .||.||.|.||. ...   ..     ..|  .|.|||||  | |...||.||.|||.| ||.|. ||  .      ... 
DLKPENILFDSKKDDSWVIYNIKVIDWGTSKKFDQNQKIEDKKMSQRCGTPYYIAPEVLQKK-YNEKCDIWSCGVILYILLCGYPPFYGKNDQEIMEKVK

DGLLIFKSPIWSSVSRDAFDLLKKMVNVYPQYRITIDQALKHSWF
.|   |. | |...| .| || .|| .. |. |.. .|||.| ||
KGKYSFEGPEWDHISDEAKDLIRKMLCYDPKKRMSAQQALQHPWF
Kinase 23204.AA CAMK-Unique 546-677 27 1.6e-45 148.15 In-house 182-363 (363) Show / Hide 
Range on Protein: 546-677
Range on HMM: 182-363/363
Sequence Identity: 27% (50 aa)

DLKLENILYERDSP-------------DSEIKIIDFGLSKQVPKEQKAR-RHSIVGSETYMAP--------------EVLSSKNYDKSC----DVWSLGV
|||||||..    .             .. ||..||||....   ..    ....|.. ||||              ||.    ||  |    | |||||
DLKLENIMVCYSFKDNNHHRDFPYDWSNWHIKLCDFGLCCHYNHNKMCHMMQTMCGTPCYMAPEIVFCKNYQEMTRDEVINMQCYDQQCSPASDIWSLGV

IMYRLLSGELPF--------------KQRQQILDGLL-IFKSPIWSS---VSRDAFDLLKKMVNVYPQYRITIDQALKHSWF
||| .|.|..||              .... |. | .  |... |..   .|  | |..|.  .| | .|... ..|.|.|.
IMYYMLCGCPPFDCECEDRDYENHDKEIFECICKGDYCNFDWKMWHGPDYISQEAKDFVKCCMTVDPDHRWSAKELLEHQWI
Kinase 23204.AA Pkinase 546-677 31 3.8e-44 157.17 Pfam 133-293 (293) Show / Hide 
Range on Protein: 546-677
Range on HMM: 133-293/293
Sequence Identity: 31% (51 aa)

DLKLENILYE-RDSPDSEIKIIDFGLSKQV-PKEQKARRHSIVGSETYMAPEVLS-SKNYDKSCDVWSLGVIMYRLLSGELPFKQR------------QQ
|||.||||.  .. .|. .||.||||.||.    .    ....|.  ||||||.  .. |....|.||.|.|.| .|.|..||...            ..
DLKPENILIDNNGHIDACVKICDFGLAKQFDY-NNS--MTTFCGTPWYMAPEVIRGGQYYGPKVDMWSCGCILYEMLCGRPPFPGHCWHDNHDQMQMICR

ILDGLLIFKSPIWSSVS-----------------RDAFDLLKKMVNVYPQYRITIDQALKHSWF
|... | | .| |.|.|                 ... |..|.. .. |. |.|..|.|.| ||
IMGPPLHFDWPWWCSISYFFFRHWHFHWTFHNWSEECKDFIKWCLCKDPKKRPTAEQILQHPWF
Kinase 23204.AA Ciliate-E2-Unclassified 546-677 31 1.2e-41 142.29 In-house 169-352 (352) Show / Hide 
Range on Protein: 546-677
Range on HMM: 169-352/352
Sequence Identity: 31% (59 aa)

DLKLENILYERDSPDSEIKIIDFGLSK---QVPKEQKAR------------RHSIVGSETYM----APEVLSSKNYD----KSCDVWSLGVIMYRLLSGE
|.|.||||.  .    .|||||||.||   | ....  .             ....|.  ||    ||||| ..|||    ..||.||||||.| .| |.
DIKPENILFDNNGKNYYIKIIDFGISKKYQQNNNCD-TNQQQKMQIWKQQMMWTFCGTPNYMPQYTAPEVLQGQNYDHSKAYKCDIWSLGVILYEMLFGY

LPFK----------------------QRQQILDG-LLIFKSP---IWSSVSRDAFDLLK----KMVNVYPQYRITIDQALKHSWF
.||.                      ..|.|... . ..|.|   |   .|  | |...    || .. | .|||..|.|.| ||
YPFYDNNCEQHQQLITQWINNAYRKQLYQNIKQKNIQFPKFPWQQIPKHWSPEAKDFINDLLQKMLKKNPNKRITFEQILNHPWF
Kinase 23204.AA CAMKL 546-677 36 1.9e-41 129.92 In-house 152-297 (297) Show / Hide 
Range on Protein: 546-677
Range on HMM: 152-297/297
Sequence Identity: 36% (56 aa)

DLKLENILYERDSPDS-EIKIIDFGLSKQ-----VPKEQKARRHSIVGSETYMAPEVLSS--KNYD-KSCDVWSLGVIMYRLLSGELPFKQRQ-------
|.|.||||   |. ..  |||||||.| .     ....|| . .   ||  |||||....  | || .  |.||.|||.| .. |.|||..         
DIKPENILL--DENGNNNIKIIDFGFSNMYRPCIFGPGQKLKTF--CGSPPYMAPEIFQGNNKPYDGPKVDIWSCGVILYAMVCGYLPFDDDTYNKQGKD

----QILDGLLIFKSPIWSSVSRDAFDLLKKMVNVYPQYRITIDQALKHSWF
       .  . .. |||..|| |. ||..|| .| | .|.||.| ..| |.
NIYLYWKIMCG-YYPPIWYHVS-DCRDLIRKMLQVNPEKRPTIHQIMNHPWM
Kinase 23204.AA CDPK 442-545 43 2.9e-35 105.76 In-house 1-113 (271) Show / Hide 
Range on Protein: 442-545
Range on HMM: 1-113/271
Sequence Identity: 43% (49 aa)

YEFIKQIGQGQFGSVFLAKRR-KQPFDEVAIKIINLNQIKKIPLQYI-KREVQISKSLDHPNIIKFQETYIDKKNIYIVME--YCTGGNL-----SQKQF
| . |..|.|.||.|...| . |.    ||.|||. ...|.   |.. ..|. | |.||||||||. |.| |.||.|||||  |||||.|     ....|
YKIKKVLGKGHFGQVRKVKHKQKTNQERVAMKIIPKSRVKDKEQQQQFFNEIEILKQLDHPNIIKIYEFYQDEKNYYIVMETEYCTGGELFDYIIEKGHF

SEQEVLNIMKKLL
.|.|  .||...|
TEKEAAYIMRQIL
Kinase 23204.AA CAMKL 442-527 37 6.3e-34 105.55 In-house 1-110 (297) Show / Hide 
Range on Protein: 442-527
Range on HMM: 1-110/297
Sequence Identity: 37% (41 aa)

YEFIKQIGQGQFGSVFLAKRRKQPFDEVAIKIINLNQIKKIPLQY-------------IKREVQISKSLD---HPNIIKFQETYIDKKN------IYIVM
|...|..|.| || | ||. .. .  .||||||. . |...|                |.||.|| |.|.   ||||||. |.. ....      ||.||
YRIGKTLGKGSFGKVKLATHIRTTGEKVAIKIIDKKKIWNDPWMKKNKCGQKHESDMRIRREIQIMKMLNIGKHPNIIKLYEVIETPEHDIETKKIYLVM

EYCTGGN--L
||| ||.  |
EYCSGGEMDL
Kinase 23204.AA Pkinase 442-545 35 7.3e-31 110.21 Pfam 1-118 (293) Show / Hide 
Range on Protein: 442-545
Range on HMM: 1-118/293
Sequence Identity: 35% (42 aa)

YEFIKQIGQGQFGSVFLAKRRKQPFDEVAIKIINLNQIKKIPLQYIKR--EVQISKSLDHPNIIKFQETYIDKKNIYIVMEYCTGG----NLS-------
|.....||.| ||.|....... .  .||.|||..  .|.  .|.  |  |.|| |.|.||||... ... ||..||.||||| ||     |.       
YHIGRKIGSGSFGCVYKCHHKGTGK-IVAVKIIKKRHEKSWKDQTHRRLSEIQIMKRLNHPNIVRLYDWFEDKDHIYMVMEYCEGGLYVMDLFDYISTWR

QKQF--SEQEVLNIMKKLL
.. |  ||.|. ..|. .|
HGCFYFSEWECKFYMYQIL
Kinase 23204.AA Ciliate-E2-Unclassified 442-545 28 5.9e-26 87.03 In-house 1-153 (352) Show / Hide 
Range on Protein: 442-545
Range on HMM: 1-153/352
Sequence Identity: 28% (43 aa)

YEFIKQIGQGQFGSVFLAKRRKQPFD---EVAIKIINLNQIKKIP----------LQYIK--------REVQ-ISKSLDHPNIIKFQETYIDKKNIYIVM
|..|||||||.||.|......|| .    . ..||.. .| ..            .. .|        .. | | ....||.|.|. ..  ||.||||||
YKIIKQIGQGGFGKVYKCQHKKQKQYYAMKYMKKIQIYKQKQIMNKDEIMNEMKEMNNKKKYHQRKYNKIMQQILLNHPHPFIVKMFYCFQDKQNIYIVM

EYCTGGNLSQ----------------------KQFSEQEVL-----NIMKKLL
||| ||.|.|                      |.|.||...     .... .|
EYCEGGDLWQYIKKRKKQKQKGNDLFHNMKQRKIFTEQQAKYKKAKFYFAQIL
Kinase 23204.AA CAMK-Unique 442-545 25 2.7e-25 80.3 In-house 1-167 (363) Show / Hide 
Range on Protein: 442-545
Range on HMM: 1-167/363
Sequence Identity: 25% (43 aa)

YEFIKQIGQGQFGSVFLAKRRKQPFDEVAIKIINLNQIKKIPLQY------------------IKREVQISKSLDHPNIIKFQET----YIDKK------
|.... ||.| || |. .. |. . .. |.|....   . . .                     |||.|| |..|||||||. ..    . |.|      
YKMHRIIGHGNFGHVYECMDRETG-KKWACKMVKKQTHGNKKQKQQRNFDLRYKITEKRRDMKLKREHQIWKMVDHPNIIKLYDWNNPIFCDRKYPLCDL

---------NIYIVMEYCTGG---NLSQK----------------------QFSE--QEVLNIMKKLL
         ..|||||||.||    . ||                      .|||   ....|| .||
IIKTPRALPYMYIVMEYCQGGDLFDWIQKWDEFYFNFIIKFDFNILKRCQGHFSERCWDTCFIMQCLL
Kinase 23204.AA Pkinase_Tyr 442-527 29 4e-16 55.22 Pfam 1-94 (270) Show / Hide 
Range on Protein: 442-527
Range on HMM: 1-94/270
Sequence Identity: 29% (28 aa)

YEFIKQIGQGQFGSVFLAKRR---KQPFDEVAIKIINLNQIKKIP---LQYIKREVQISKSL-DHPNIIKFQETYI-DKKN--IYIVMEYCTGGNL
 .|.|..|.|.||.|.... .   ...  .||.|..  ..    .   ..   ||..| |.| .||||...    . ...   |||||||. .|.|
ITFGKKLGEGAFGEVYKGTWKGDPDNTKIPVAVKML--KEGAMHEQNCREDFMREAKIMKQLGHHPNIVRLYGVCTDQGEPNQIYIVMEYMPHGDL
Kinase 23204.AA RSK 445-544 26 1.8e-14 49.62 In-house 1-113 (278) Show / Hide 
Range on Protein: 445-544
Range on HMM: 1-113/278
Sequence Identity: 26% (30 aa)

IKQIGQGQFGSVFLAKRR--KQPFDEVAIKIINLNQIKKIP--LQYIKREVQISKSLD-HPNIIKFQETYIDKKNIYIVMEYCTGGNL-----SQKQ---
.|. ||| .|.||| ..   ..   . | |... . |..    . . ..|..| .    ||.|..  ... ... .|..|||| || |      .|.   
LKVLGQGGYGKVFLCRKCTHHDTGQIYAMKVLKKAKIVQRQKDTRHTMTERNILERCQQHPFIVTLHYAFQTEGKLYLIMEYCRGGELFTHLQKEKHFGC

FSEQEVLNIMKKL
||| |.  .| ..
FSEDEACFYMAEI
Kinase 23204.AA TyrKc 442-658 18 3.8e-13 -10.16 SMART 1-280 (280) Show / Hide 
Range on Protein: 442-658
Range on HMM: 1-280/280
Sequence Identity: 18% (55 aa)

YEFIKQIGQGQFGSVFLAKRRKQPFDEVAIKIINLNQIKKIPLQYIKREVQISKSL--DHPNIIKFQETYIDK-------KNIYIVMEYCTGGNL-----
 ...|..| |.|| |.... .     .||.| .. .      .. . || .| ..|  .||||...    ...       . ..|||||. .|.|     
ITLGKKLGEGAFGEVYKGTWK----IQVAVKMLKEDA-----REDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPHGDLKDYLR

-SQKQFSEQEVLNIM------------KKLL--DLKLENILYERDSPDSEIKIIDFGLSKQVPKE---------QKA----RRH--SIVGSETYMAPEVL
 ...... .. |...            |..   ||   |.|. ..     .|| |||||. .  .          ..     ..    .     ||||..
KHRPKLCMKDLLSFCWQIACGMEYLHSKNCIHRDLAARNCLVGENH---TVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGKTMLPI---RWMAPECI

SSKNYDKSCDVWSLGVIMYRLLS-GELPFKQ-----------RQQILDGLLIFKSPI--------------------WSS--VSRDAFDLLKKMV
  . .    |||| || |. ... |. |              .... .|    . |                     |     .|  |  ...  
NYGKFTTKSDVWSFGVCMWEIFTYGQQPYPGMIQQMMSNQEVIEYVKQGYRMPQPPNDYPMSFVCCPDEMYQIMKQCWHEDPEDRPTFSEIHECF
Kinase 23204.AA Pkinase_Tyr 551-616 28 0.232436 5.23 Pfam 141-205 (270) Show / Hide 
Range on Protein: 551-616
Range on HMM: 141-205/270
Sequence Identity: 28% (20 aa)

NILYERDSPDSEIKIIDFGLSKQV-PKEQK--ARRHSIVGSETYMAPEVLSSKNYDKSCDVWSLGVIMY
|.| ..   .  .|| ||||.. . ....   .| ..       ||||... . .    |||| || |.
NCLVTE---NNVVKICDFGLARDIYNDDYYYRKRGGGK-LPIKWMAPECINYGKFTTKSDVWSFGVLMW