Gene 5677 (Tetrahymena)

5677

Species: Tetrahymena
Alias: PreTt05677, 655, 3681.m00105, 50.m00246, TTHERM_00442770, 5677
External Links: Tetrahymena Genome Database (TGD)
Annotation:

Classification

Group: AGC
Family: AGC-Sar
Subfamily: Ciliate-E2b

Sequence

Name Sequence Type Origin Length Description Download
5677.AA Protein None 930 None Fasta, JSON
5677.kin_dom Protein Kinase Domain None 258 None Fasta, JSON
5677.NA RNA None 2793 None Fasta, JSON

Protein domain

Protein domains of 5677.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
CNMP_binding 5677.AA cNMP_binding 252-332 29 1.1e-17 63.38 Pfam 6-91 (91) Show / Hide 
Range on Protein: 252-332
Range on HMM: 6-91/91
Sequence Identity: 29% (26 aa)

KSDFVFKQGDQASTYFIIEKGECQIIINGDVKR-----TLQHGQCFGELALLYGA-PRSASVKALGVCGFWAIDRNTFKKAIAEVVH
| ...|.|||...  .|...|.....  ..  |     .|. |..|||.||...  ||.|.|.||. |  |.|.|..|.. ...   
KGEVIFHQGDPCDHFYIVLSGKVKVYK-DEDGREQILGFLGPGDFFGEMALFTNQNPRTATVVALTDCECWRIPREDFRQLMQQHPE
CNMP 5677.AA cNMP 230-342 25 2.5e-17 64.79 SMART 1-123 (123) Show / Hide 
Range on Protein: 230-342
Range on HMM: 1-123/123
Sequence Identity: 25% (31 aa)

VFSLLSDQDKEEIIKKMFY-CENKSDFVFKQGDQASTYFIIEKGECQIIIN---------GDVKRTLQHGQCFGELALLYGAPRSASVKAL-GVCGFWAI
.|. |..|. .|.. .|.     . . .|.|||.... .||..|. ...           . . ..|. |. |||||||  .||.|...|.   | .| |
MFKNLDEQELRELCDHMEPRHYPAGEYIFRQGDPGDHFYIIVSGWVRVYKTRVQHMEDGREQIVGFLGPGDFFGELALL-RRPRTAAARACCECCTIWRI

DRNTFKKAIAEVVHREYGENRSFI
|.. |  ....  .. | . ....
DFQHFMQQLQQHPQHMYRMLQQLA
CNMP_binding 5677.AA cNMP_binding 365-451 33 2.3e-22 79.43 Pfam 1-91 (91) Show / Hide 
Range on Protein: 365-451
Range on HMM: 1-91/91
Sequence Identity: 33% (31 aa)

TQVFKKGEIIVADGDMASSYYIIKKGKVAIYKDEKMIR-----EMVAGETFGEQALFENS-KRGATVKAVEDDSRCIALGKDDIQRVLGDKVQ
.. .||||.|.  || ... ||...||| .|| ..  |     .. .|. ||| |||.|. .| |||.| ..|..|... ..|..... .  .
VRHYKKGEVIFHQGDPCDHFYIVLSGKVKVYK-DEDGREQILGFLGPGDFFGEMALFTNQNPRTATVVA-LTDCECWRIPREDFRQLMQQHPE
CNMP 5677.AA cNMP 347-461 20 7.7e-19 69.83 SMART 1-123 (123) Show / Hide 
Range on Protein: 347-461
Range on HMM: 1-123/123
Sequence Identity: 20% (25 aa)

FFNSMTNEQKDSIANVLITQVFKKGEIIVADGDMASSYYIIKKGKVAIYKD---------EKMIREMVAGETFGEQALFENSKRGATVKAVEDDSRCIAL
.| ... ..  ...... ......||.|.. || ... ||| .|.| .||.         |. .... .|. ||| ||. .. | |...|.  ....  .
MFKNLDEQELRELCDHMEPRHYPAGEYIFRQGDPGDHFYIIVSGWVRVYKTRVQHMEDGREQIVGFLGPGDFFGELALL-RRPRTAAARACCECCTIWRI

GKDDIQRVLGDKVQVIMYNNMIKW
 ...... |..  |  ...     
DFQHFMQQLQQHPQHMYRMLQQLA
CNMP_binding 5677.AA cNMP_binding 486-571 15 0.609699 5.81 Pfam 1-91 (91) Show / Hide 
Range on Protein: 486-571
Range on HMM: 1-91/91
Sequence Identity: 15% (15 aa)

QTNYQKGVICFPAGQPVQKLIFLLEGSIAYEGGNK--------IAEKGGLFGDHWLLQKYKDEKLSKNVIFSEDTLLAEISFQQLYEQIGGKNI
  .|.|| . | .|.|.. . ..|.|..  .  ..        . ..| .||.  |..     . . .|.  .|. ...|. ... . .     
VRHYKKGEVIFHQGDPCDHFYIVLSGKVKVYK-DEDGREQILGFLGPGDFFGEMALFTNQ--NPRTATVVALTDCECWRIPREDFRQLMQQHPE
Kinase 5677.AA Ciliate-E2b 607-864 67 2.3e-208 638.95 In-house 1-272 (272) Show / Hide 
Range on Protein: 607-864
Range on HMM: 1-272/272
Sequence Identity: 67% (184 aa)

MISIKKLGFGQFGSVYLVKS-KSDSNYYALKCISKAQVIEQSLEKHLLQEKKVLESAQFPFIMKFIRTFRDNNNVYFLVEYVRGMELFDVIREIG--LLN
|| |||||||||||||||.. |....|||.|||||.|.|.|..|||.||||.||| ...||||||||.|.|....||..|...||||||||||||  ||.
MIYIKKLGFGQFGSVYLVWNTKNTKQYYAMKCISKNQIIQQNMEKHMLQEKNVLEKCNHPFIMKFIRSFKDDQHMYFMMEFCNGMELFDVIREIGRLLLS

TYDSQFYIGSLLLCIEYLHTNSIIYRDIKPENIMIDYKGYMKLIDMGTAKFLKGKSG---RTFTIIGTPHYMAPEIIT-----GKGYSYSVDLWSIGICL
||||||||.|..||.||||...||||||||||||.|.|||||||||||||....|..   |||||||||||||||||.     ||||.|.||.||.||||
TYDSQFYIASICLCLEYLHNQNIIYRDIKPENIMVDHKGYMKLIDMGTAKHMYKKNEQMTRTFTIIGTPHYMAPEIIQSLQPGGKGYTYKVDIWSVGICL

YEFMCGAVPFAEDADDPYEIYEEIIKK--PLQYPGFLKDKNS-KTLMNQLLNKTPELRLGGSYAALKANPWF
||||||.||.|||..||||||.|||||  ..|.| ..|||.. |.||.|.|.|.||.||||||..||..|||
YEFMCGYVPWAEDVQDPYEIYQEIIKKYDEIQFPSYCKDKMADKKLMLQCLQKMPEVRLGGSYSWLKSHPWF
Kinase 5677.AA AGC 607-864 25 3.5e-109 282.9 In-house 1-395 (395) Show / Hide 
Range on Protein: 607-864
Range on HMM: 1-395/395
Sequence Identity: 25% (100 aa)

MISIKKLGFGQFGSVYLVKSK------SDSNYYALKCISKAQ-VIEQS--LEKHLLQE------------KKVLESAQ----------FPFIMK-FIRTF
   .| .| | || ||||. |      .   |||.|...|.  ...     ..| . |            ...|| ..           ||| |    .|
FEFLKVIGKGSFGKVYLVRKKDGCHKKDTGKYYAMKVLKKKHKIVIKKKNMVEHTMTEHWKQDQGYVWEERNILEKCNHTHNHPIKSHHPFIVKILHYSF

RDNNN--VYFLVE----YVR------GMELFDVIR---EIGLLNTYDSQFYIGS-------LLLCIEYLHT-NSIIYRD-IKPENIMIDYKGYMKLIDMG
 |...  .||. |    ||.      |.|||  ..     | ..   ..||.         ..|..||||  . ||.|| .|||||..| .|. || | |
QDKDHTYLYFVMEYMPRYVNDLYCGGGCELFLHLQGRRKEGRFDEERARFYAAEMQKICGCIVLALEYLHSHMGIIHRDYLKPENILLDEDGHIKLTDFG

TAKFLKGKS--------------------------------------------------GRTFTIIG--TPHYMAPEIITGKGYSYSVDLWS--IGICLY
 .| ....                                                    || |. |  ||.||||||.    |....| ||   |...|
LCKEGMNDGEKGQQSQSNMKFHWHNKKYQKSNMDTNKCNPNNWQRNNMSQEDDTTRKKRDRTWTFCGPCTPEYMAPEIL----YGKACDWWSFGLGCLMY

EFMCGAVPFAEDADD--------PYEIYEEII------KKPLQYP----------GFLKDKNSKTLMNQLLNKTPELRLG--GS------YAALKANPWF
|...|  ||  | ..        |.|... |.      ......|           .. ... | |...||.| || |||  |.      .  .|. |||
EMLTGYPPFYGDNPQENRHPFRNPMEMFQKIMNGRYFINWKVKFPFPEDPQFPEDRWF-SPEAKDLIKKLLCKDPEKRLGCGGNDFGDKGAEEIKNHPWF
Kinase 5677.AA Ciliate-E2 607-864 26 1.3e-94 320.67 In-house 1-365 (365) Show / Hide 
Range on Protein: 607-864
Range on HMM: 1-365/365
Sequence Identity: 26% (101 aa)

MISIKKLGFGQFGSVYLVKS-----------------------KSDSNYYALKCISKAQVIEQSLEKHLL----------QEKKVLESAQFPFIMKFIRT
 . |||.|.|.|||||..|                        | ....||.|...| |..... |.|..          .||..||. ..|.|.|.. .
YKFIKKIGQGNFGSVYKCKVWKVQKQFAIKIIDQKQQRQQMQEKVKIKIYAMKIMKKNQIEQIKQEIHIMREINCFYKKINEKNILEQLNHPNIIKMYEC

FR--DNNNVYFLVEYVRGMELFD-------------------VIREIGLLNTYDSQ-------FYIGSLLLCIEYLHTNS-IIYRDIKPENIMIDYKGYM
|   |.||.|.  ||. |..|||                   ...||. . ..  |       |||....|..|||| .  ||.||||||||..      
FQEKDDNNIYLVMEYCQGGDLFDYIKNNKKKRNHEIEKDKYFTEKEIKYIMKQILQGFKTKAEFYIACIILALEYLHSKNNIIHRDIKPENILF-----I

KLIDMGTAKFLKGKSG-------------------------------RTFTIIGTPHYMAPEIITGKG---------YSYSVDLWSIGICLYEFMCGAVP
|.||.|..|... ..                                 ..||.|||.||||||. ||.         |.|..|.||.|..|||...|  |
KIIDFGLSKKYDDDNQNRTHKQQCKWYMFKNDTSRTPGYMDQIIQQNMFNTICGTPGYMAPEILNGKKYDNQQKQKGYDYKCDIWSLGVILYEMLFGKPP

FAEDADDPYEIYEEIIKKPLQYP----------------GFLKDKNS-KTLMNQ----LLNKTPELRLGGSYAALKANPWF
|          ...|.......|                 ..|  .. | |...    .|.| || |.. ..  .. .|||
F----------QQQIKQCKIDFPCPEWQKDTQCIQCKWKSWKKWSQECKDLIKKFGKRMLQKDPEKRIT-GWEQILNHPWF
Kinase 5677.AA PKA 607-864 38 2.9e-80 272.95 In-house 1-263 (263) Show / Hide 
Range on Protein: 607-864
Range on HMM: 1-263/263
Sequence Identity: 38% (102 aa)

MISIKKLGFGQFGSVYLVKSKSDSNYYALKCISKAQVIEQSLEKHLLQEKKVLESAQFPFIM-KFIRTFRDNNNVYFLVEYVRGMELFDVIREIGLLNTY
   |. || | || |.|...|.. ||||.|...|....    . | . ||..| . ..|||  | . || |... |.. ||| | |.|. .|  | .. .
FEIIQTLGTGSFGRVMLCRHKHSGNYYAMKMLKKQEIVRLKQVEHVHNEKNILQNIKHPFIVKKMYWTFQDDRYLYMVMEYVPGGEMFSYLRKSGRFSNP

DSQFYIG-SLLLCIEYLHTNSIIYRDIKPENIMIDYKGYMKLIDMGTAKFLKGKSGRTFTIIGTPHYMAPEIITGK-GYSYSVDLWSIGICLYEFMCGAV
...||.     | .||||.  ||||| |||||.|| .|. |. | | || ...   ||.|. ||| |.|||||..| |.  ||| |. ||  ||.. |  
HAKFYAASQIVLALEYLHSQNIIYRDLKPENILIDKNGHIKITDFGFAKKVDD---RTWTLCGTPEYLAPEIIQSKNGHGKSVDWWALGILIYEMLAGYP

PFAEDADDPYEIYEEIIKKPLQYPGFLKDKNS---KTLMNQLLNKTPELRLGGSYA---ALKANPWF
|| ..  || .||| |..  ...| .. |..    | | ..||.. .. |.|   .     |  .||
PFYDHNRDPMQIYEKICNGKIKFPRHF-DSDANYFKDLIKKLLQVDLTKRYGNMKNGVNDIKNHKWF
Kinase 5677.AA S_TKc 607-864 30 6.7e-79 269.34 SMART 1-231 (231) Show / Hide 
Range on Protein: 607-864
Range on HMM: 1-231/231
Sequence Identity: 30% (82 aa)

MISIKKLGFGQFGSVYLVKSKSDSNYYALKCISKAQVIEQSLEKHLLQEKKVLESAQFPFIMKFIRTFRDNNNVYFLVEYVRG--MELFDVIREIGL---
   ..|.| | ||.||... |..  ..|.|.|.          .|...| ..|.. . |.| |.. .|.| ...|.  ||. |   .|||.|.. |    
YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK----------EHIRREIQILKK-HHPNIVKLYDVFQD-DHLYMVMEYCDGDLGDLFDYIKKRGRHGL

---LNTYDSQFYIGSLLLCIEYLHTNSIIYRDIKPENIMIDYKGYMKLIDMGTAKFLKGKSGRTFTIIGTPHYMAPEIITGKGYSY-SVDLWSIGICLYE
   ..  . .||.  ... .||.| . ||.||.|||||..|     |..| | |..|        |..|||.|||||..   ||.. ..| ||.|..|||
RFPFPE-HARFYMYQICCALEYCHSHGIIHRDLKPENILLDE--HIKICDFGLARQL-------TTFCGTPWYMAPEVL---GYGKCKCDWWSCGCILYE

FMCGAVPFAEDADDPYEIYEEIIKKPLQYPGFLKDKNSKTLMNQLLNKTPELRLGGSYAAL-----KANPWF
..||  ||     ....... |            ..  | .....|.| || |..   |       |. |||
MLCGYPPFP----QMQMMFKKIG-----------SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF
Kinase 5677.AA AktR 608-864 36 9.1e-70 238.09 In-house 2-268 (268) Show / Hide 
Range on Protein: 608-864
Range on HMM: 2-268/268
Sequence Identity: 36% (98 aa)

ISIKKLGFGQFGSVYLVKSK-SDSNYYALKCISKAQVIEQSLEKHLLQEKKVLE-SAQFPFIMKFIRTFRDNNNVYFLVEYVRGMELFDVIREIGLLNTY
  .| || | || ||||. |  .  .||.| |.|   ||. ...|...|....|  ...||| |.  .| .... .|. ||..| |||.... .. ..  
HVYKCLGKGAFGKVYLVQKKRDNQKQYAMKMIKKKKIIERNQMHHTITERNIMEMCCNHPFIVKLHYCFQTKEKLFFIMEYCPGGELFQHLKKKKKFSEE

DSQFYIGSLLLCIEYLHTN-SIIYRDIKPENIMIDYKGYMKLIDMGTAK--FLKGKSGRTFTIIGTPHYMAPEIITG-KGYSYSVDLWSIGICLYEFMCG
...||.   ||..|||| .  |||||.|||||..|  |. |..| | .|  | . .. .. .. |||.|||||.||  ||. .|||.|..|| .|| . |
QARFYFAQILLALEYLHQHMNIIYRDLKPENILLDEDGHVKITDFGLSKLQFMMHYDEKAYSFCGTPEYMAPEMITKKKGHNKSVDWWAFGIFIYEMVTG

AVPFAEDADDPYEIYEEIIK-KPLQYP----GFLKDKNSKTLMN-QLLNKTPELRLG-G--SYAALKANPWF
  ||  . .    ... |.  .. .||     ..||     | . .||.| |. ||| .  .   .|  |||
CPPFYHKNQNQMFQKIKIKQQNKFPYPSYFSSQCKD-----LIQRKLLCKNPNKRLGYYCNGWEEIKSHPWF
Kinase 5677.AA Ciliate-E2-Unclassified 608-864 27 3.6e-67 229.48 In-house 2-352 (352) Show / Hide 
Range on Protein: 608-864
Range on HMM: 2-352/352
Sequence Identity: 27% (96 aa)

ISIKKLGFGQFGSVYLVKSKSDSNYYALKCISKAQVIEQSLEKHL---------LQEKK-------------VLESAQFPFIMKFIRTFRDNNNVYFLVE
. ||..| |.||.||... |..  |||.| ..|.|.. | . ..          ...||              | . . |||.|.. .|.| .|.|.  |
KIIKQIGQGGFGKVYKCQHKKQKQYYAMKYMKKIQIYKQKQIMNKDEIMNEMKEMNNKKKYHQRKYNKIMQQILLNHPHPFIVKMFYCFQDKQNIYIVME

YVRGMELFDVIREI-----------------GLLNTYDSQ-----FYIGSLLLCIEYLHTNS-IIYRDIKPENIMIDYKG---YMKLIDMGTAKFLKG--
|..| .|.. |..                    .  . ..     ||.  .|...|||| .  ||.||||||||..| .|   | |.|| | .|...   
YCEGGDLWQYIKKRKKQKQKGNDLFHNMKQRKIFTEQQAKYKKAKFYFAQILQGLEYLHHKNNIIHRDIKPENILFDNNGKNYYIKIIDFGISKKYQQNN

-------------KSGRTFTIIGTPHYM----APEIITGKGYS----YSVDLWSIGICLYEFMCGAVPF-AEDADDPY-------------EIYEEIIKK
             |. .. |..||| ||    |||.. |..|.    |..| || |..|||.. |  || ... .. .             ..|..|..|
NCDTNQQQKMQIWKQQMMWTFCGTPNYMPQYTAPEVLQGQNYDHSKAYKCDIWSLGVILYEMLFGYYPFYDNNCEQHQQLITQWINNAYRKQLYQNIKQK

PLQYPGFLK----DKNS---KTLMN----QLLNKTPELRLGGSYAALKANPWF
..|.| | .    .. |   | . |    ..|.| |. |.  ..  ..  |||
NIQFPKFPWQQIPKHWSPEAKDFINDLLQKMLKKNPNKRI--TFEQILNHPWF
Kinase 5677.AA PKG 607-821 40 3e-66 226.41 In-house 1-213 (260) Show / Hide 
Range on Protein: 607-821
Range on HMM: 1-213/260
Sequence Identity: 40% (87 aa)

MISIKKLGFGQFGSVYLVKSKSD-SNYYALKCISKAQVIEQSLEKHLLQEKKVLESAQFPFIMKFIRTFRDNNNVYFLVEYVRGMELFDVIREIGLLNTY
.  |  || | || | ||..... |  .||||. |......  . |   ||....... .|| .  |||||.  ||.| |   | ||  ..|. |    .
LKIIATLGVGGFGRVELVQYNHQKSRTFALKCMKKRHIVDTRQQEHIMSEKNIMMECRCDFIVRLYRTFRDQKYVYMLMEACMGGELWTILRDRGHFDDK

DSQFYIGSLLLCIEYLHTNSIIYRDIKPENIMIDYKGYMKLIDMGTAKFLKGKSGRTFTIIGTPHYMAPEIITGKGYSYSVDLWSIGICLYEFMCGAVPF
 ..||..  .   .|||   ||||| ||||.| | .||.||.| | ||.. |....| |  ||| | |||||  ||   ||| |. ||  .| . |  ||
TTRFYCACVVEAFDYLHRKNIIYRDLKPENLMLDNRGYCKLVDFGFAKKI-GQGRKTWTFCGTPEYVAPEIILNKGHDRSVDYWALGILMCELLTGNPPF

AEDADDPYEIYEEIIK
   . ||  .|  | |
S--GSDPMKTYNIILK
Kinase 5677.AA Pkinase 607-864 28 7e-66 229.97 Pfam 1-293 (293) Show / Hide 
Range on Protein: 607-864
Range on HMM: 1-293/293
Sequence Identity: 28% (86 aa)

MISIKKLGFGQFGSVYLVKSKSDSNYYALKCISKAQVIEQSLEKHLL-QEKKVLESAQFPFIMKFIRTFRDNNNVYFLVEYVRGM----ELFDVIR--EI
   ..|.| | ||.||. . |...  .|.|.|.|    .. .. |.. .| ... . . |.| .....|.|....|.  ||..|     .|||.|.  . 
YHIGRKIGSGSFGCVYKCHHKGTGKIVAVKIIKKRHEKSWKDQTHRRLSEIQIMKRLNHPNIVRLYDWFEDKDHIYMVMEYCEGGLYVMDLFDYISTWRH

GLL--NTYDSQFYIGSLLLCIEYLHTNSIIYRDIKPENIMIDYKGYM----KLIDMGTAKFL-KGKSGRTFTIIGTPHYMAPEIIT-GKGYSYSVDLWSI
| .     . .||.  .|  .||.| ..||.||.|||||.|| .|.     |..| | ||..   ... . |. |||.|||||.|  |..|...|| ||.
GCFYFSEWECKFYMYQILRGLEYCHSMGIIHRDLKPENILIDNNGHIDACVKICDFGLAKQFDY-NNS-MTTFCGTPWYMAPEVIRGGQYYGPKVDMWSC

GICLYEFMCGAVPFA-E----DADDPYEIYEEIIKKPLQYPGFLKD--------------------KNSKTLMNQLLNKTPELRLGGSYAALKANPWF
|. |||..||  ||  .    . .|.......| ..|| .. . ..                    .. | ... .|.| |. |..   . ..  |||
GCILYEMLCGRPPFPGHCWHDN-HDQMQMICRIMGPPLHFDWPWWCSISYFFFRHWHFHWTFHNWSEECKDFIKWCLCKDPKKRPT--AEQILQHPWF
Kinase 5677.AA RSK 610-864 31 1.2e-64 221.06 In-house 1-278 (278) Show / Hide 
Range on Protein: 610-864
Range on HMM: 1-278/278
Sequence Identity: 31% (88 aa)

IKKLGFGQFGSVYLVKSK---SDSNYYALKCISKAQVIEQSL-EKHLLQEKKVLESAQ-FPFIMKFIRTFRDNNNVYFLVEYVRGMELFDVIREIGL---
.| || | .|.|.|.. .       .|| | ..|| ..      .| ..| ..||  |  ||| .   .|...  .|   ||.|| |||. ... .    
LKVLGQGGYGKVFLCRKCTHHDTGQIYAMKVLKKAKIVQRQKDTRHTMTERNILERCQQHPFIVTLHYAFQTEGKLYLIMEYCRGGELFTHLQKEKHFGC

LNTYDSQFYIGSLLLCIEYLHTNSIIYRDIKPENIMIDY---KGYMKLIDMGTAKFLKGK-SGRTFTIIGTPHYMAPEIIT----GKGYSYSVDLWSIGI
.   . .||.  . | .|.||.  ||.||.|||||. |     |  ||.| | .| .. . ...| | ..| .|||||...    ..|.. ..|.|| |.
FSEDEACFYMAEIVLAVEHLHQQGIIHRDLKPENILYDDESNEGHIKLTDFGFCKQFRCDHNQWTMTFCYTIEYMAPEMLKRANQQGGHDKACDWWSLGV

CLYEFMCGAVPFAEDAD-DPYEIYEEIIKKP--LQYP--GFLKDKNSKTLMNQLLNKTPELRLG---GSYAALKANPWF
 .||   |..||. ..| .. || . | |.   |  |   .|  .. | | ...| . |. |||   .  . .|..|||
LMYEMLTGCPPFQGPNDNNRKEIMKRIQKGKFSLTMPNWQYL-SQEAKDLIRKMLHRDPHKRLGCGPQDAEEIKQHPWF
Kinase 5677.AA Akt 610-864 35 3.6e-61 194.25 In-house 4-264 (264) Show / Hide 
Range on Protein: 610-864
Range on HMM: 4-264/264
Sequence Identity: 35% (94 aa)

IKKLGFGQFGSVYLVKSKSDSNYY-ALKCISKAQVIEQSLEKHLLQEKKVLESAQFPFIMKFIRTFRDNNNVYFLVEYVRGMELFDVIREIGLLNTYDSQ
.| || | || |.||| |.. ..| |.| ..| . |..   .| ..|...|.  ..||| .    | .... ||  .|. | |||  ..  .  .     
LKVLGKGSFGKVFLVKKKDTQKWYYAMKVLKKDYIIQKNQVEHTKTERNILQHCNHPFIVNLHYSFQTQDKLYFVMDYCNGGELFYHLQRKRRFSEDRAR

FYIGSLLLCIEYLHTNSIIYRD-IKPENIMIDYKGYMKLIDMGTAKFL-KGKSGRTFTIIGTPHYMAPEIITGKGYSYSVDLWS-IGICLYEFMCGAVPF
||.  . | ||.|| ..|||||  |||||..|..|. .| | | .|   .    .| |. ||| |.||||. |.|.. .|| |. .|. .||.|||. ||
FYCAEIILAIEHLHSKNIIYRDYLKPENILMDKDGHICLTDFGLCKENIIKDHDKTKTFCGTPEYLAPEILNGNGHTKAVDWWGSLGCVMYEMMCGRPPF

AEDADDPYEIYEEIIKKPLQYP--GFLKDKNSKTLMNQLLNKTPELRLG---GSYAALKANPWF
 .  .|  . .. |  .|...|   .. ... |.| ..|||| |..|||   .    .|. |||
YN--QDHHQMFKKIKNQPVKFPDKDWI-SPECKDLISGLLNKDPKKRLGGGPNDAQEIKRHPWF
Kinase 5677.AA Delta 607-864 32 1.6e-57 197.39 In-house 1-259 (259) Show / Hide 
Range on Protein: 607-864
Range on HMM: 1-259/259
Sequence Identity: 32% (84 aa)

MISIKKLGFGQFGSVYLVKSKSDSNYYALKCISKAQVIEQSLEKHLLQEKKVLE-SAQFPFIMKFIRTFRDNNNVYFLVEYVRGMELFDVIREIGLLNTY
 .  | || | || | |.  |   .|||.||. |  |.|       . |..||  ... ||. ... ||  .....| .||. | .|   | ...  . .
FHFHKVLGKGSFGKVMLAELKGKNKYYAIKCLKKDVVLEDDDVECTMVERRVLALAWEHPFLCHLFCTFQTKEHLFFVMEYLNGGDLMYHIQQCHRFDEK

DSQFYIGSLLLCIEYLHTNSIIYRDIKPENIMIDYKGYMKLIDMGTAKFLKGKSGRTFTIIGTPHYMAPEIITGKGYSYSVDLWSIGICLYEFMCGAVPF
 ..||   ... ...||.. |||||.| .|...|. | .|. | | .|    . ... |  ||| |.||||| |. |. ||| || |. .|| . |  ||
RARFYACEIICGLQFLHKKGIIYRDLKLDNVLLDCDGHIKIADFGMCKENMYGEKKASTFCGTPDYIAPEIIKGQKYNHSVDWWSFGVLMYEMLIGQSPF

AEDADDPYEIYEEIIKKPLQYPGFLKDKNSKTLMNQLLNKTPELRLGG---SYAALKANPWF
  . .|  |... |..    || ... |..| ....|....|| |||        ... ..|
HGEDED--ELFWSICNDRPWYPRWIT-KEAKDCLKKLFERDPEKRLGVQYCPKGDIRQHCFF
Kinase 5677.AA TyrKc 607-860 18 5e-11 -44.4 SMART 1-280 (280) Show / Hide 
Range on Protein: 607-860
Range on HMM: 1-280/280
Sequence Identity: 18% (56 aa)

MISIKKLGFGQFGSVYLVKSKSDSNYYALKCISKAQVIEQSLEKHLLQEKKVLESA--QFPFIMKFIRTFRDN-------NNVYFLVEYVRGMELFDVIR
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ITLGKKLGEGAFGEVYKGTWK---IQVAVKMLKEDA------REDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPHGDLKDYLR

EIGLLNTYDSQFYIGSLLLC---------IEYLHTNSIIYRDIKPENIMIDYKGYMKLIDMGTAKFLKGK-----SGRTFTI---IGTP-----HYMAPE
. .          .    |.          |||| . .| ||.   |.... .. .|  | | ..... .     |. . .     |.        ||||
KHRPK--------LCMKDLLSFCWQIACGMEYLHSKNCIHRDLAARNCLVGENHTVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGKTMLPIRWMAPE

IITGKGYSYSVDLWSIGICLYE-FMCGAVPFAEDA---DDPYEIYEEIIKKPLQYPGFL--------KDKNSKTLMNQLLNKTPELRLGGSYAALKA
 |  . ..   | || |.|..| |  |. |  ...    ...|..| . .     .             .   ..| |  .  || |   |    . 
CINYGKFTTKSDVWSFGVCMWEIFTYGQQPYPGMIQQMMSNQEVIEYVKQGYRMPQPPNDYPMSFVCCPDEMYQIMKQCWHEDPEDRPTFSEIHECF
Kinase 5677.AA Pkinase_Tyr 772-807 31 0.010257 9.82 Pfam 181-218 (270) Show / Hide 
Range on Protein: 772-807
Range on HMM: 181-218/270
Sequence Identity: 31% (12 aa)

MAPEIITGKGYSYSVDLWSIGICLYEFMC-GAVP-FAE
|||| |  . ..   | || |....| .  |. | ...
MAPECINYGKFTTKSDVWSFGVLMWEIFTYGEQPTYPG
Kinase 5677.AA Pkinase_Tyr 607-623 52 0.689798 3.63 Pfam 1-17 (270) Show / Hide 
Range on Protein: 607-623
Range on HMM: 1-17/270
Sequence Identity: 52% (9 aa)

MISIKKLGFGQFGSVYL
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ITFGKKLGEGAFGEVYK