Gene 11236 (Tetrahymena)

11236

Species: Tetrahymena
Alias: 3.m01969, 3824.m02994, 180, PreTt11236, TTHERM_00047570, 11236
External Links: Tetrahymena Genome Database (TGD)
Annotation:

Classification

Group: Other
Family: Ciliate-E2
Subfamily: Ciliate-E2-Unclassified

Sequence

Name Sequence Type Origin Length Description Download
11236.AA Protein None 381 None Fasta, JSON
11236.kin_dom Protein Kinase Domain None 269 None Fasta, JSON
11236.NA RNA None 1146 None Fasta, JSON

Protein domain

Protein domains of 11236.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Kinase 11236.AA AGC 110-306 29 3.2e-79 203.64 In-house 140-395 (395) Show / Hide 
Range on Protein: 110-306
Range on HMM: 140-395/395
Sequence Identity: 29% (80 aa)

KRHLSEQHTKFYAAE-------ILLGLEALHS-KKIIHRD-IKPENILISSTGHVKITDFGISIFSDKDPKVG---------------------------
.....|....|||||       |.|.|| ||| ..||||| .||||||. . ||.|.|||| .    .|. .|                           
EGRFDEERARFYAAEMQKICGCIVLALEYLHSHMGIIHRDYLKPENILLDEDGHIKLTDFGLCKEGMNDGEKGQQSQSNMKFHWHNKKYQKSNMDTNKCN

---YQENNRMSIISQSTQNEEVQSRISD----IKQFQG--TLQYNAPEILKFQEFSYQADFWA--FGILIFMLLKGYHPFVDYNSDDP------DFATYY
    |.|| ||      | |   . . .     . | |  | .| |||||     ....| |.  .|.|.. .| || || . | ...       . .. 
PNNWQRNN-MS------Q-E-DDTTR-KKRDRTWTFCGPCTPEYMAPEIL----YGKACDWWSFGLGCLMYEMLTGYPPFYGDNPQENRHPFRNPMEMFQ

NIINGR-----ILQYNET--------PSLSIQAESLISLLLDINQYSRLGAG-------GIEQIKNHQFF
.|.|||      ....          ...| .| .||. ||  .   |||.|       |.|.|||| .|
KIMNGRYFINWKVKFPFPEDPQFPEDRWFSPEAKDLIKKLLCKDPEKRLGCGGNDFGDKGAEEIKNHPWF
Kinase 11236.AA Ciliate-E2 38-306 21 1.7e-73 250.49 In-house 1-365 (365) Show / Hide 
Range on Protein: 38-306
Range on HMM: 1-365/365
Sequence Identity: 21% (82 aa)

FTIVKKIGSGGYGDIYLLKL-----------------------QQDGKYYVQKRI--SKLKLKSHKDSVI----------IEKEIMKTIKSPFIQSLKAS
. ..||||.|..|..|. |                        ....|.|  |..  .... .. .....          .||.|......|.|  .. .
YKFIKKIGQGNFGSVYKCKVWKVQKQFAIKIIDQKQQRQQMQEKVKIKIYAMKIMKKNQIEQIKQEIHIMREINCFYKKINEKNILEQLNHPNIIKMYEC

KQ--DD-------------------------------------NYVKRHLSEQHTK-------FYAAEILLGLEALHSKK-IIHRDIKPENILISSTGHV
 |  ||                                      .  .....| ..       ||.|.|.|.|| ||||. ||||||||||||.     .
FQEKDDNNIYLVMEYCQGGDLFDYIKNNKKKRNHEIEKDKYFTEKEIKYIMKQILQGFKTKAEFYIACIILALEYLHSKNNIIHRDIKPENILF-----I

KITDFGISIFSDKDPKVGYQENNRMSIISQSTQNEEVQSRISDIKQ---------FQGTLQYNAPEILK---------FQEFSYQADFWAFGILIFMLLK
||.|||.| . |.| . ... .... .. .  ..........|  |         . ||. | |||||.         ... .|..|.|..|......| 
KIIDFGLSKKYDDDNQNRTH-KQQCKWYMF-KNDTSRTPGYMD--QIIQQNMFNTICGTPGYMAPEILNGKKYDNQQKQKGYDYKCDIWSLGVILYEMLF

GYHPFVDYNSDDPDFATYYNIINGRILQYN----------------ETPSLSIQAESLISL----LLDINQYSRLGAGGIEQIKNHQFF
|..||             ...|    ....                .. ..| ..  ||.     .|. ..  |..  |.|||.||..|
GKPPF-------------QQQIKQCKIDFPCPEWQKDTQCIQCKWKSWKKWSQECKDLIKKFGKRMLQKDPEKRIT--GWEQILNHPWF
Kinase 11236.AA Ciliate-E2-Unclassified 38-306 26 1.1e-68 234.47 In-house 1-352 (352) Show / Hide 
Range on Protein: 38-306
Range on HMM: 1-352/352
Sequence Identity: 26% (95 aa)

FTIVKKIGSGGYGDIYLLKLQQDGKYYVQKRISKLKLKS-----HKDSVIIEK-EIMKTIK-------------------SPFIQSLKASKQDD------
..|.|.||.||.|..|...  ....||..| ..| . ..     .||  |. . ..|. .|                   .|||  .   .||.      
YKIIKQIGQGGFGKVYKCQHKKQKQYYAMKYMKKIQIYKQKQIMNKD-EIMNEMKEMNNKKKYHQRKYNKIMQQILLNHPHPFIVKMFYCFQDKQNIYIV

----------NYVK-------------------RHLSEQHTK-----FYAAEILLGLEALHSKK-IIHRDIKPENILISSTG---HVKITDFGISIFSDK
          .| |                   ....||..|     ||.|.||.||| ||.|. ||||||||||||... |   ..||.|||||.....
MEYCEGGDLWQYIKKRKKQKQKGNDLFHNMKQRKIFTEQQAKYKKAKFYFAQILQGLEYLHHKNNIIHRDIKPENILFDNNGKNYYIKIIDFGISKKYQQ

DPKVGYQEN-NRMSIISQSTQNEEVQSRISDIKQFQGTLQYNAPEILKFQEFS----YQADFWAFGILIFMLLKGYHPFVDYNSDDPD-----------F
...    .. ..|.|..|  ..  ... .  . |      |.|||.|. |. .    |..|.|..|.... .| ||.|| |.|... .           .
NNNCD-TNQQQKMQIWKQQMMWTFCGTPNYMP-Q------YTAPEVLQGQNYDHSKAYKCDIWSLGVILYEMLFGYYPFYDNNCEQHQQLITQWINNAYR

ATYYNIINGRILQYNETP------SLSIQAESLIS----LLLDINQYSRLGAGGIEQIKNHQFF
  .|..|. ...|... |       .| .|. .|.     .|. |. .|.   ..|||.||..|
KQLYQNIKQKNIQFPKFPWQQIPKHWSPEAKDFINDLLQKMLKKNPNKRI---TFEQILNHPWF
Kinase 11236.AA S_TKc 38-306 24 5.6e-57 196.52 SMART 1-231 (231) Show / Hide 
Range on Protein: 38-306
Range on HMM: 1-231/231
Sequence Identity: 24% (74 aa)

FTIVKKIGSGGYGDIYLLKLQQDGKYYVQKRISKLKLKSHKDSVIIEKEIMKTIKSPFIQSLKASKQ-----------DD------NYVKRH--------
..|..|||.|..|  |. .   .|...  |.|.        .... | .|.|  . |.|  |. . |           |        | |..        
YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK--------EHIRREIQILKK-HHPNIVKLYDVFQDDHLYMVMEYCDGDLGDLFDYIKKRGRHGLRFP

LSEQHTKFYAAEILLGLEALHSKKIIHRDIKPENILISSTGHVKITDFGISIFSDKDPKVGYQENNRMSIISQSTQNEEVQSRISDIKQFQGTLQYNAPE
..| |..||...|...|| .||..|||||.||||||...  |.||.|||.. .                                  . | ||. | |||
FPE-HARFYMYQICCALEYCHSHGIIHRDLKPENILLDE--HIKICDFGLARQL---------------------------------TTFCGTPWYMAPE

ILKFQEFSY-QADFWAFGILIFMLLKGYHPFVDYNSDDPDFATYYNIINGRILQYNETPSLSIQAESLISLLLDINQYSRLGAGGIEQ----IKNHQFF
.|    ...  .| |..|.... .| || ||        . .. ...|             | .| ..|. .|. .   |..|  . |    ||.|..|
VL---GYGKCKCDWWSCGCILYEMLCGYPPFP-------QMQMMFKKIG------------SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF
Kinase 11236.AA PDK1 113-306 32 3.9e-51 154.61 In-house 107-307 (307) Show / Hide 
Range on Protein: 113-306
Range on HMM: 107-307/307
Sequence Identity: 32% (70 aa)

LSEQHTKFYAAEILLGLEALHSKKIIHRDIKPENILISSTGHVKITDFGIS----IFSD-----------KDPKVGYQENNRMSIISQSTQNEEVQSRIS
...  ..||||||...|| |||..|||||.||||||... .|..||||| .    |...           . .    |.|. |.     .  |  |.|  
FDMDCCRFYAAEIIDALEHLHSNGIIHRDLKPENILLDKDMHIMITDFGTAGFDKILPEYQSQQQNQFQQQFQ----QHNKGMD-----KPEEDKQTR--

DIKQFQGTLQYNAPEILKFQEFSYQADFWAFGILIFMLLKGYHPFVDY-NSDDPDFATYYNIINGRILQYNETPS--LSIQAESLISLLLDINQYSRLGA
  | | || .|  || |   | ....| ||.| .|. .. |  ||..       .. |   |..   .||  ...   .  |. |.. ||......||..
-CKSFVGTAEYVSPELLTDKECTPSCDIWALGCIIYQMVAGQPPFRGMNDATNNEYHTFQKIMK---CQYDFPDNFRFPPCAKDLVKKLLVRDPNDRLTS

----GGIEQIKNHQFF
    ||..|||.| ||
CDECGGYQQIKAHPFF
Kinase 11236.AA MAST 115-306 28 1.9e-48 154.11 In-house 98-334 (334) Show / Hide 
Range on Protein: 115-306
Range on HMM: 98-334/334
Sequence Identity: 28% (70 aa)

EQHTKFYAAEILLGLEALHSKKIIHRDIKPENILISSTGHVKITDFGISIF----------SDK--------------DPKVGYQE--------------
|  .|.| ||. |.|| |||. |.|||.||.|.||.|.||.|.|||| | .          ...              ... .|..              
EWMAKMYIAETVLCLEYLHSHGIVHRDLKPDNMLIDSNGHIKLTDFGLSKVGFMDDLNMMYEGYTPPNIFNNSTDPMNKNQQDYSQFPGDFGINGNTNKN

--NNRMSIISQSTQNEEVQSRISDIKQFQGTLQYNAPEILKFQE-FSYQADFWAFGILIFMLLKGYHPFVDYNSDDPDFATYYNIINGR--ILQYNET--
  .   .   . .||   .  |   ||  ||..| |||....|   .   | |. || .. .| |. ||.| . .     .. ||.| .     ..|.  
QIQQQQEQPQCQQQN-MRPHNIHQNKQCCGTPDYIAPEVILGQGTHGKPVDWWSMGIIMYEFLVGCPPFNDDTPE----EIFQNILNRNCNEIEWPEGGD

----PSLSIQAESLISLLLDINQYSRLGAG-GIEQIKNHQFF
      .|  |  ||. ||. . . ||||. | ...|.| ||
INDDEAMSPEAQDLIEKLLQPDPRKRLGANNGADEVKQHPFF
Kinase 11236.AA AktR 110-306 33 4.1e-46 159.52 In-house 95-268 (268) Show / Hide 
Range on Protein: 110-306
Range on HMM: 95-268/268
Sequence Identity: 33% (69 aa)

KRHLSEQHTKFYAAEILLGLEALHSK-KIIHRDIKPENILISSTGHVKITDFGISIFSDKDPKVGYQENNRMSIISQSTQNEEVQSRISD---IKQFQGT
|...||. ..||.|.|||.|| ||.. .|| ||.||||||. . ||||||||| |                             |  ...    . | ||
KKKFSEEQARFYFAQILLALEYLHQHMNIIYRDLKPENILLDEDGHVKITDFGLSK---------------------------LQFMMHYDEKAYSFCGT

LQYNAPEILKF-QEFSYQADFWAFGILIFMLLKGYHPFVDYNSDDPDFATYYNIINGRILQYNETPSLSIQAESLIS-LLLDINQYSRLG--AGGIEQIK
 .| |||...  .   ...|.|||||.|. .. |. || . |  .     . .|.. .... .... .| |. .||   ||. |.. |||  . |.|.||
PEYMAPEMITKKKGHNKSVDWWAFGIFIYEMVTGCPPFYHKNQNQ----MFQKIKIKQQNKFPYPSYFSSQCKDLIQRKLLCKNPNKRLGYYCNGWEEIK

NHQFF
.| .|
SHPWF
Kinase 11236.AA RSK 110-306 31 6.7e-46 158.82 In-house 95-278 (278) Show / Hide 
Range on Protein: 110-306
Range on HMM: 95-278/278
Sequence Identity: 31% (66 aa)

KRH---LSEQHTKFYAAEILLGLEALHSKKIIHRDIKPENILISS---TGHVKITDFGISIFSDKDPKVGYQENNRMSIISQSTQNEEVQSRISDIKQFQ
..|   .||   .||.||| | .| ||...|||||.||||||  .    ||.|.|||| .  .                         . .  .  . | 
EKHFGCFSEDEACFYMAEIVLAVEHLHQQGIIHRDLKPENILYDDESNEGHIKLTDFGFCKQF-------------------------RCDHNQWTMTFC

GTLQYNAPEILK---FQE-FSYQADFWAFGILIFMLLKGYHPFVDYNSDDPDFATYYNIINGR-ILQYNETPSLSIQAESLISLLLDINQYSRLGAG--G
.|..| |||.||    |.  . ..| | .|.|....| |. ||     |.    .  .| .|.  |   . ..||  | .||. .|  .   |||.|  .
YTIEYMAPEMLKRANQQGGHDKACDWWSLGVLMYEMLTGCPPFQG-PNDNNRKEIMKRIQKGKFSLTMPNWQYLSQEAKDLIRKMLHRDPHKRLGCGPQD

IEQIKNHQFF
.|.||.|..|
AEEIKQHPWF
Kinase 11236.AA Pkinase 110-306 26 9.4e-43 152.25 Pfam 100-293 (293) Show / Hide 
Range on Protein: 110-306
Range on HMM: 100-293/293
Sequence Identity: 26% (60 aa)

KRHL--SEQHTKFYAAEILLGLEALHSKKIIHRDIKPENILISSTGHV----KITDFGISIFSDKDPKVGYQENNRMSIISQSTQNEEVQSRISDIKQFQ
.. .  ||.. |||. .|| ||| .||..|||||.|||||||...||.    ||.|||.. . |                           . |  . | 
HGCFYFSEWECKFYMYQILRGLEYCHSMGIIHRDLKPENILIDNNGHIDACVKICDFGLAKQFD-------------------------Y-NNS-MTTFC

GTLQYNAPEILK-FQEFSYQADFWAFGILIFMLLKGYHPFVDY----NSDDPDFATYYNIINGRILQYNETPSLS-----------------IQAESLIS
||. | |||...  |. .. .| |..|.... .| |. || .     | .|...  . .       .. .. | |                   . ..|.
GTPWYMAPEVIRGGQYYGPKVDMWSCGCILYEMLCGRPPFPGHCWHDN-HDQMQMICRIMGPPLHFDWPWWCSISYFFFRHWHFHWTFHNWSEECKDFIK

LLLDINQYSRLGAGGIEQIKNHQFF
 .|. . ..|..   .|||..| .|
WCLCKDPKKRPT---AEQILQHPWF
Kinase 11236.AA SGK 111-163 54 5.8e-28 83.05 In-house 120-172 (283) Show / Hide 
Range on Protein: 111-163
Range on HMM: 120-172/283
Sequence Identity: 54% (29 aa)

RHLSEQHTKFYAAEILLGLEALHSKKIIHRDIKPENILISSTGHVKITDFGIS
.|..|   .|||||| . || |||..||.|| ||||||  . ||...|||| .
KHFPEDRARFYAAEIVCALEYLHSQDIIYRDLKPENILLDHQGHCCLTDFGLC
Kinase 11236.AA PKA 110-161 62 7.3e-26 92.25 In-house 94-146 (263) Show / Hide 
Range on Protein: 110-161
Range on HMM: 94-146/263
Sequence Identity: 62% (33 aa)

KRHLSEQHTKFYAA-EILLGLEALHSKKIIHRDIKPENILISSTGHVKITDFG
....|..|.||||| .| | || |||. ||.|| ||||||| . ||.||||||
SGRFSNPHAKFYAASQIVLALEYLHSQNIIYRDLKPENILIDKNGHIKITDFG
Kinase 11236.AA RSK 110-163 51 5e-22 75.54 In-house 95-152 (271) Show / Hide 
Range on Protein: 110-163
Range on HMM: 95-152/271
Sequence Identity: 51% (30 aa)

KRHLSEQHTKFYAAEILLGLEALHSKKIIHRDIKPENILISST----GHVKITDFGIS
.. .||.  |||.|||.| .| |||..|.||| ||||||....    ||.||.||| .
QKMFSEREVKFYMAEIALAMEYLHSQGIVHRDLKPENILYDDESGNPGHIKICDFGFA
Kinase 11236.AA AGC 38-108 22 2e-19 45.47 In-house 1-105 (395) Show / Hide 
Range on Protein: 38-108
Range on HMM: 1-105/395
Sequence Identity: 22% (24 aa)

FTIVKKIGSGGYGDIYLLKLQ------QDGKYYVQKRISKLK---LKS--HKDSVIIE------------KEIMKTIK----------SPFIQS-LKASK
| ..| || |..|  || .        . ||||  | ..| .   .|     . ...|            ..|.....          .||| . |. | 
FEFLKVIGKGSFGKVYLVRKKDGCHKKDTGKYYAMKVLKKKHKIVIKKKNMVEHTMTEHWKQDQGYVWEERNILEKCNHTHNHPIKSHHPFIVKILHYSF

QDDNY
||...
QDKDH
Kinase 11236.AA RSK 204-306 33 3.4e-19 65.3 In-house 167-271 (271) Show / Hide 
Range on Protein: 204-306
Range on HMM: 167-271/271
Sequence Identity: 33% (36 aa)

GTLQYNAPEILKFQEFSYQADFWAFGILIFMLLKGYHPFVDYNSDDPDFATYYNIINGR-ILQYNETPSLSIQAESLISLLLDINQYSRLGA--GGIEQI
.| .| |||.|| | ..  .|.| ||.| .  | |. ||.  . |.|. .   .| .|.  .      ..|  | .|.. .|...   ||||   |.|||
YTANYMAPEVLKRQGHDQACDWWSFGVLMYEMLTGCTPFQNKPRDTPM-NIIQRIKLGMFSMTHGNWDFISDEAKDLLRMMLHRDPHNRLGAGPNGVEQI

KNHQFF
|.| .|
KQHPWF
Kinase 11236.AA SGK 202-306 34 1.3e-17 50.56 In-house 185-283 (283) Show / Hide 
Range on Protein: 202-306
Range on HMM: 185-283/283
Sequence Identity: 34% (37 aa)

FQGTLQYNAPEILKFQEFSYQADFWAFGILIFMLLKGYHPFVDYNSDDPDFATYYNIINGRILQYNETPSLSIQAESLISLLLDINQYSRLGAG-GIEQI
| ||. | |||.|. |...   | |  |.. . .. |  || . |        | ||||. .   .  |. | .| .|| .||  ..  |||.  . ..|
FCGTPEYLAPEVLRKQPHDRTVDWWCLGCVLYEMMYGLPPFYSRNKQ----QMYDNIINQPL---QIPPQMSNDAWDLIQGLLQKDPKKRLGTKRDFMEI

KNHQFF
|||.||
KNHPFF
Kinase 11236.AA TyrKc 38-306 17 9.2e-11 -48.64 SMART 1-280 (280) Show / Hide 
Range on Protein: 38-306
Range on HMM: 1-280/280
Sequence Identity: 17% (56 aa)

FTIVKKIGSGGYGDIYLLKLQQDGKYYVQKRIS----KLKLKSHKDSVIIEKEIMKTI--KSPFIQSLKASKQDD-----------------------NY
 |  ||.|.| .| .|. ..           |     .||  . .   . | .||. .  . | |  | .   ..                       .|
ITLGKKLGEGAFGEVYKGTWK----------IQVAVKMLKEDA-REDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPHGDLKDY

V-KRH--LSEQHTKFYAAEILLGLEALHSKKIIHRDIKPENILISSTGHVKITDFGISIFSDKDPKVGYQENNRMSIISQSTQNEEVQSRIS-DIKQFQG
  |..  |. ..   ..  |  | | ||||..||||.   |.|... ..|||.||| | . . | . |               .... .  . . . .  
LRKHRPKLCMKDLLSFCWQIACGMEYLHSKNCIHRDLAARNCLVGENHTVKISDFGLSRDIYDDDQQG--------------ESKDYYRKKEHKGGKTML

TLQYNAPEILKFQEFSYQADFWAFGILIF-MLLKGYHPFVD---YNSDDPDFATYYNIINGRILQYNET--------PSLSIQAESLISLLLDINQYSRL
 .   ||| ... .|. . | |.||.... ..  |  |  .      . ...  . .. .|. .   .          .  .    ...   . .  .| 
PIRWMAPECINYGKFTTKSDVWSFGVCMWEIFTYGQQPYPGMIQQ--MMSNQEVIEYVKQGYRMPQPPNDYPMSFVCCPDEMYQ--IMKQCWHEDPEDRP

GAGGIEQIKNHQFF
    |     |..|
TFSEI-----HECF
Kinase 11236.AA AktR 38-108 28 1.4e-08 29.59 In-house 1-75 (268) Show / Hide 
Range on Protein: 38-108
Range on HMM: 1-75/268
Sequence Identity: 28% (21 aa)

FTIVKKIGSGGYGDIYLLKLQ-QDGKYYVQKRISK--LKLKSHKDSVIIEKEIMK-TIKSPFIQSLKASKQDDNY
|.. | .|.|..|. || .   ...|.|  | |.|  .. .  .. .| |. ||.  .. |||  |. . |....
FHVYKCLGKGAFGKVYLVQKKRDNQKQYAMKMIKKKKIIERNQMHHTITERNIMEMCCNHPFIVKLHYCFQTKEK
Kinase 11236.AA SGK 38-100 23 1.7e-08 21.87 In-house 1-91 (283) Show / Hide 
Range on Protein: 38-100
Range on HMM: 1-91/283
Sequence Identity: 23% (21 aa)

FTIVKKIGSGGYGDIYLLKLQQD------------------GKYYVQKRISKLKLK---------SHKDSVIIEK-EIMKTIKSPFIQSLK
| . |.|| |..|  |. |  .|                  .| |. | ..|              .   . .|.  |.| .|.||| .|.
FDFLKVIGKGSFGKVYQVKHKDDETCQRVWLIFQSLLSQSEDKFYAMKVLQKQHIINEYRQDLKKKEQKHIMAERNVILKNMKHPFIVNLH
Kinase 11236.AA PKA 224-306 37 3.4e-08 33.56 In-house 181-263 (263) Show / Hide 
Range on Protein: 224-306
Range on HMM: 181-263/263
Sequence Identity: 37% (33 aa)

DFWAFGILIFMLLKGYHPFVDYNSDDPDFATYYNIINGRILQYNETPSLSIQA---ESLISLLLDINQYSRLG--AGGIEQIKNHQFF
| ||.||||. .| || || | | |   ...|  |.||.| ..   .... .|    .||. ||  .   |.|   .|...|||| .|
DWWALGILIYEMLAGYPPFYDHNRD--PMQIYEKICNGKI-KFP--RHFDSDANYFKDLIKKLLQVDLTKRYGNMKNGVNDIKNHKWF
Kinase 11236.AA Pkinase 38-96 37 5.1e-08 29.45 Pfam 1-62 (293) Show / Hide 
Range on Protein: 38-96
Range on HMM: 1-62/293
Sequence Identity: 37% (23 aa)

FTIVKKIGSGGYGDIYLLKLQQDGKYYVQKRISKLKLKSHKDSVII---EKEIMKTIKSPFI
..|..|||||..|  |. . . .|| .. |.|.| . || ||   .   | .||| ...|.|
YHIGRKIGSGSFGCVYKCHHKGTGKIVAVKIIKKRHEKSWKDQTHRRLSEIQIMKRLNHPNI
Kinase 11236.AA S_TK_X 307-368 25 5.9e-08 33.68 SMART 1-79 (79) Show / Hide 
Range on Protein: 307-368
Range on HMM: 1-79/79
Sequence Identity: 25% (20 aa)

SGIDWKKVSE--LKEQPPFIPSNQ----DNALLQNFDKEVLQ-----SVDNQKMSQIPHTNQ------FTPYPNFTYEE
.||||.|.     . .|||.|  .    .   . |||.|        ..|.. .|.. . |.       .|...|||  
RGIDWDKLYNQQKEIEPPFKPKIKEVYASPTDTSNFDPEFTEETPMLTPDDPPLSNSMWQNEMETEIPPDPFRGFTYVF
Kinase 11236.AA MAST 38-96 31 7.6e-08 21.03 In-house 1-61 (334) Show / Hide 
Range on Protein: 38-96
Range on HMM: 1-61/334
Sequence Identity: 31% (19 aa)

FTIVKKIGSGGYGDIYLLKLQQDGKYYVQKRISKLK--LKSHKDSVIIEKEIMKTIKSPFI
|...| |. |.||  || | .  .. .  |.| |    .|   |.|..|. | . ...||.
FEFIKPISKGAYGKVYLVKHKKTNDRFAMKVIKKSDMINKNMVDQVQVERNILAMYQNPFV
Kinase 11236.AA Pkinase_Tyr 132-163 46 9.5e-07 23.48 Pfam 127-158 (270) Show / Hide 
Range on Protein: 132-163
Range on HMM: 127-158/270
Sequence Identity: 46% (15 aa)

LHSKKIIHRDIKPENILISSTGHVKITDFGIS
|.||..||||.   |.|......|||.||| .
LESKNCIHRDLAARNCLVTENNVVKICDFGLA
Kinase 11236.AA PKA 38-108 35 2e-06 25.7 In-house 1-74 (263) Show / Hide 
Range on Protein: 38-108
Range on HMM: 1-74/263
Sequence Identity: 35% (27 aa)

FTIVKKIGSGGYGDIYLLKLQQDGKYYVQKRISK-----LKLKSHKDSVIIEKEIMKTIKSPFIQ-SLKASKQDDNY
| |.. .|.| .|  .| . ...|.||  | ..|     || . |   |. || |.. ||.|||  ..... |||.|
FEIIQTLGTGSFGRVMLCRHKHSGNYYAMKMLKKQEIVRLKQVEH---VHNEKNILQNIKHPFIVKKMYWTFQDDRY
Kinase 11236.AA RSK 38-109 23 9.5e-05 13.15 In-house 1-76 (271) Show / Hide 
Range on Protein: 38-109
Range on HMM: 1-76/271
Sequence Identity: 23% (18 aa)

FTIVKKIGSGGYGDIYLLKLQ---QDGKYYVQKRISKLKLKSH-KDSVIIEKEIMKTIKSPFIQSLKASKQDDNYV
. . ..|| | ....|. |     . ...|  | | | ...   ..    |  |.  . .|||  |. . ||  .|
YELHECIGQGSFSKVYVCKKCQHKDTNQHYAMKIIKKATRDVKDRVCWEEERIILRYGHHPFIVKLHYVFQDEGKV
Kinase 11236.AA Pkinase_Tyr 210-233 37 0.00167 12.49 Pfam 182-205 (270) Show / Hide 
Range on Protein: 210-233
Range on HMM: 182-205/270
Sequence Identity: 37% (9 aa)

APEILKFQEFSYQADFWAFGILIF
||| ... .|. . | |.||.|..
APECINYGKFTTKSDVWSFGVLMW
Kinase 11236.AA RSK 41-109 27 0.003204 8.06 In-house 1-76 (278) Show / Hide 
Range on Protein: 41-109
Range on HMM: 1-76/278
Sequence Identity: 27% (21 aa)

VKKIGSGGYGDIYLLKLQ---QDGKYYVQKRISKLKLKSH-KD--SVIIEKEIMKTIK-SPFIQSLKASKQDDNYV
.|  | ||||  .| .     . |..|  | ..| |.. . ||   .  | .|..... .||| .|. . |.. ..
LKVLGQGGYGKVFLCRKCTHHDTGQIYAMKVLKKAKIVQRQKDTRHTMTERNILERCQQHPFIVTLHYAFQTEGKL
Kinase 11236.AA Pkinase_Tyr 38-54 41 2.033163 2.04 Pfam 1-17 (270) Show / Hide 
Range on Protein: 38-54
Range on HMM: 1-17/270
Sequence Identity: 41% (7 aa)

FTIVKKIGSGGYGDIYL
 |. ||.|.| .|..|.
ITFGKKLGEGAFGEVYK