Gene 19068 (Tetrahymena)

19068

Species: Tetrahymena
Alias: 19068, 702, PreTt19068, 3673.m00031, TTHERM_00715960, 113.m00107
External Links: Tetrahymena Genome Database (TGD)
Annotation:

Classification

Group: Other
Family: ULK
Subfamily: ULK

Sequence

Name Sequence Type Origin Length Description Download
19068.AA Protein None 659 None Fasta, JSON
19068.kin_dom Protein Kinase Domain None 256 None Fasta, JSON
19068.NA RNA None 1980 None Fasta, JSON

Protein domain

Protein domains of 19068.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Kinase 19068.AA Ciliate-E2-Unclassified 20-275 27 3.4e-82 279.38 In-house 1-352 (352) Show / Hide 
Range on Protein: 20-275
Range on HMM: 1-352/352
Sequence Identity: 27% (99 aa)

YTLIQKLGSGGFSSVYLCEDENQNKFA-----LKKIREVK-------ERYIQQELKALMTIK-------------------SPYIVKYVENFVYKEYPII
|..|...|.|||..||.|....|. ..     .|||...|       .  | .|.|... .|                   .|.|||... |  |....|
YKIIKQIGQGGFGKVYKCQHKKQK-QYYAMKYMKKIQIYKQKQIMNKD-EIMNEMKEMNNKKKYHQRKYNKIMQQILLNHPHPFIVKMFYCFQDKQNIYI

IMEYCEQGTLDSYLKLYEG---------------GVLHEKKAL-----NMFAYILQGI-RAIHEAGFIHRDLKGSNILMQNG----LPKISDFGLARKAT
.|||||.|.|  |.| ...                 . |..|.     ..||.||||.   .|. ..||||.| .|||..|.     .||.|||...|  
VMEYCEGGDLWQYIKKRKKQKQKGNDLFHNMKQRKIFTEQQAKYKKAKFYFAQILQGLEYLHHKNNIIHRDIKPENILFDNNGKNYYIKIIDFGISKKYQ

T----------------SQMIQSSSCTPSYA----APEVLQGKQYG----YKVDIWSLGVILYRIIFGCLPFEGSSHTK-------------LLKKIQDL
.                .||... ..||.|     |||||||..|.    ||.|||||||||| ..|| .||.. . ..              .  .|. 
QNNNCDTNQQQKMQIWKQQMMWTFCGTPNYMPQYTAPEVLQGQNYDHSKAYKCDIWSLGVILYEMLFGYYPFYDNNCEQHQQLITQWINNAYRKQLYQNI

CQGGFQISKAPK----KKTQDISIGLIK-LFKEIFVIDYQKRIGFKELYSNSII
.|. .|..|.|.    |. ..  . .|. |.. ... .  |||.|...    ..
KQKNIQFPKFPWQQIPKHWSPEAKDFINDLLQKMLKKNPNKRITFEQILNHPWF
Kinase 19068.AA Ciliate-E2 20-275 22 1.5e-77 263.98 In-house 1-365 (365) Show / Hide 
Range on Protein: 20-275
Range on HMM: 1-365/365
Sequence Identity: 22% (86 aa)

YTLIQKLGSGGFSSVYLCED------------------------ENQNKFALKKIREVKERYIQQELKALMTIK----------------SPYIVKYVEN
| .|.|.|.|.|.|||.|..                         .....|.| ... . ..| ||.. ...|.                .|.|.|..| 
YKFIKKIGQGNFGSVYKCKVWKVQKQFAIKIIDQKQQRQQMQEKVKIKIYAMKIMKKNQIEQIKQEIHIMREINCFYKKINEKNILEQLNHPNIIKMYEC

FV--YKEYPIIIMEYCEQGTLDSYLK---LYEGGVLH------EKKALNMFAYILQ---------------GIRAIHEAG-FIHRDLKGSNILMQNGLPK
|    ...  ..||||..|.| .|.|   . ..  ..      ||........|||               ... .|. .  ||||.| .|||.    .|
FQEKDDNNIYLVMEYCQGGDLFDYIKNNKKKRNHEIEKDKYFTEKEIKYIMKQILQGFKTKAEFYIACIILALEYLHSKNNIIHRDIKPENILF----IK

ISDFGLARKATTS--------------------------------QMIQSSSCTPSYAAPEVLQGKQ---------YGYKVDIWSLGVILYRIIFGCLPF
|.||||..|....                                .|...  .|| | |||.|.||.         |.||.||||||||||. .|| .||
IIDFGLSKKYDDDNQNRTHKQQCKWYMFKNDTSRTPGYMDQIIQQNMFNTICGTPGYMAPEILNGKKYDNQQKQKGYDYKCDIWSLGVILYEMLFGKPPF

EGSSHTKLLKKIQDLCQGGFQISKAPKK-----------KTQDISIGLIKLFKE----IFVIDYQKRIG-FKELYSNSII
           .|  .|. ...... .            .....|   . |.|     ... | .|||. ....  . ..
-----------QQQIKQCKIDFPCPEWQKDTQCIQCKWKSWKKWSQECKDLIKKFGKRMLQKDPEKRITGWEQILNHPWF
Kinase 19068.AA S_TKc 20-275 28 7.4e-73 249.28 SMART 1-231 (231) Show / Hide 
Range on Protein: 20-275
Range on HMM: 1-231/231
Sequence Identity: 28% (78 aa)

YTLIQKLGSGGFSSVYLCEDEN-QNKFALKKIREVKERYIQQELKALMTIKSPYIVKYVENFVYKEYPIIIMEYCEQ--GTLDSYLKLYEGGV----LHE
|....|.|.|.|..||.| . . . ..|.|.|.    . |..|.. |.  . |.|||. . |.  ..  ..||||..  |.| .|.| . ..     ..|
YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK----EHIRREIQILKK-HHPNIVKLYDVFQD-DHLYMVMEYCDGDLGDLFDYIKKRGRHGLRFPFPE

KKALNMFAYILQGIRAIHEAGFIHRDLKGSNILMQNGLPKISDFGLARKATTSQMIQSSSCTPSYAAPEVLQGKQYGY-KVDIWSLGVILYRIIFGCLPF
  |  ... |....  .|. |.|||||| .|||. .   ||.||||||.        .   || | |||||   .||. |.|.||.|.|||  . |. ||
-HARFYMYQICCALEYCHSHGIIHRDLKPENILLDE-HIKICDFGLARQL------TTFCGTPWYMAPEVL---GYGKCKCDWWSCGCILYEMLCGYPPF

EGSSHTKLLKKIQDLCQGGFQISKAPKKKTQDISIGLIKLFKEIFVIDYQKRIGFKELYS-------NSII
.   . ...|||                     |  .. . . ... | .||..  |.            .
P--QMQMMFKKIG--------------------SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF
Kinase 19068.AA ULK 20-275 28 1.3e-66 227.6 In-house 1-329 (329) Show / Hide 
Range on Protein: 20-275
Range on HMM: 1-329/329
Sequence Identity: 28% (94 aa)

YTLIQKLGSGGFSSVYLCEDENQN-----KFALKKIR---EVKERY----------IQQELKALMTIK----SPY----IVKYVENFVYK--EYPIIIME
| |...||.| |  ||  ......     |.| |.|    . .. .          ...| | . ..|    ...    |||. . |  .   .  ||||
YCLNHCLGKGSFGKVYKGRNKKTKDYVNEKVACKMIDKQKMNQKNNEQEGQYMWQLLKNEIKIMKKLKSPNRHKNHHPNIVKLYDWFETSNHNNIYIIME

YCEQGTLDSYLKLY--------EGGVLHEKKALNMFAYILQGIRAIHEAGFIHRDLKGSNILMQNGLPK-------------ISDFGLARKATTS----Q
||..|.|..|.| .        |.. | |..|.. |  ||.| ...|. . ||||.| .|||. || ||             |.|||.|.. . .    |
YCNGGDLEQYIKKNKKLPEDTEEKKRLSEQEAIQFFKQILNGFKELHKHNIIHRDIKPQNILIHNGQPKTDSKKVHPNGVLKIADFGFAKHVDNDNMEQQ

MIQSSS------CTPSYAAPEVLQ----GKQYG-YKVDIWSLGVILYRIIFGCLPFEGSSHTKLL-KKIQDLCQGGF----QISKAPKK-----KTQDIS
|... .      .|| | ||..||    .|.|. ||.||||||.|.| ...|  ||...  ...  ..||.| . ..    || | | .     . . ||
MMMTCVNEKRLCGTPLYMAPQILQGQGEQKPYYDYKCDIWSLGCIFYEMLYGKPPFYAW-FNDQYLQIIQKLINNPPPWPQQIKKQPLQFPKDGNDPQIS

IGLIKLFKEIFVIDYQKRIGFKELYSNSII
  .. |..  ...|  .|| . ||... ..
PECKDLIRRMLQYDEKDRISWEELFNHPWF
Kinase 19068.AA ULK 20-275 28 1.8e-65 223.8 In-house 1-324 (324) Show / Hide 
Range on Protein: 20-275
Range on HMM: 1-324/324
Sequence Identity: 28% (93 aa)

YTLIQKLGSGGFS-SVYLC--EDEN--QNKFALKKIR-----EVKER--------YIQQELKALMTIK---SPY--IVKYVENFVYK--EYPIIIMEYCE
| |...||.| |   ||    .. |  . ..| |.|      . | .         ...| . . ..|   .|.  |||. . |  .   .  ||||||.
YCLNHCLGKGSFGVKVYKGRNKKTNTQNQYVACKMIDKKKMNKKKNEQEGQYMWQLLKNEIQIMKKLKELKHPNHHIVKLYDWFETSNHNNIYIIMEYCN

QGTLDSYLKLY-------EGGVLHEKKALNMFAYILQGIRAIHEAGFIHRDLKGSNILMQNGLPK-------------ISDFGLARKATTS----QMIQS
.|.|..|.| .       |.. | |..|.. |  |..| ...|. . ||||.| .|||. || ||             |.|||.|..        ||.|.
GGDLEQYIKKNKKLPETEEKKRLSEQEAIQFFKQICNGFKELHKHNIIHRDIKPQNILIHNGQPKTDSKKVHPNGVLKIADFGFAKHVDNNNMEQQMCQT

SS------CTPSYAAPEVLQ----GKQYG-YKVDIWSLGVILYRIIFGCLPFEGSSHTKLLKKIQDLCQGG----FQISKAPKKKT---QDISI--GLIK
        .|| | ||..||    .|.|. ||.||||||.|.| ...|  ||...  ... ..||.| . |    ..| . | ..    .|. |   .. 
CVNEKRIKGTPLYMAPQILQGQGEQKPYYDYKCDIWSLGCIFYEMLYGKYPFFSW-FNDQYLYIQKLINNGKEQQIYIKNQPIQFPKPPKDPKISPECKD

LFKEIFVIDYQKRIGFKELYSNSII
|..  ...|  .|| . |.... ..
LIRRMLQYDEKDRISWEEIFNHPWF
Kinase 19068.AA Pkinase 20-225 32 2.9e-64 224.61 Pfam 1-232 (293) Show / Hide 
Range on Protein: 20-225
Range on HMM: 1-232/293
Sequence Identity: 32% (77 aa)

YTLIQKLGSGGFSSVYLCEDENQNK-FALKKIREVKERYIQQ-------ELKALMTIKSPYIVKYVENFVYKEYPIIIMEYCEQG----TLDSYLKLYEG
|....|.|||.|..||.| . . .| .|.|.|. ..|.  ..       |.. .  ...|.||.. . | .| .. ..||||| |     | .|..  ..
YHIGRKIGSGSFGCVYKCHHKGTGKIVAVKIIKKRHEKSWKDQTHRRLSEIQIMKRLNHPNIVRLYDWFEDKDHIYMVMEYCEGGLYVMDLFDYISTWRH

GVL--HEKKALNMFAYILQGIRAIHEAGFIHRDLKGSNILMQ-NGLP----KISDFGLARK--ATTSQMIQSSSCTPSYAAPEVLQ-GKQYGYKVDIWSL
|..   |. . ...  ||.|.  .|. |.|||||| .|||.  || .    ||.|||||..     ..  ..  .|| |.||||.. |. ||.|||.||.
GCFYFSEWECKFYMYQILRGLEYCHSMGIIHRDLKPENILIDNNGHIDACVKICDFGLAKQFDY-NNS-MTTFCGTPWYMAPEVIRGGQYYGPKVDMWSC

GVILYRIIFGCLPFEGS------SHTKLLKKIQD
|.|||  ..| .|| |.      .. .....| .
GCILYEMLCGRPPFPGHCWHDNHDQMQMICRIMG
Kinase 19068.AA AGC 20-224 19 5.4e-59 150.13 In-house 1-328 (395) Show / Hide 
Range on Protein: 20-224
Range on HMM: 1-328/395
Sequence Identity: 19% (66 aa)

YTLIQKLGSGGFSSVYLCED-------ENQNKFALKKIR-EV--------KERYIQQE------------LKALMTIK----------SPYIVK-YVENF
. ..  .| |.|. |||...        ..  .|.|... ..        ...... |             . |....          .|.|||     |
FEFLKVIGKGSFGKVYLVRKKDGCHKKDTGKYYAMKVLKKKHKIVIKKKNMVEHTMTEHWKQDQGYVWEERNILEKCNHTHNHPIKSHHPFIVKILHYSF

VYKEY--PIIIMEYCE--------QGTLDSYLKLY---EGGVLHEKKALNMFAY-------ILQGIRAIHE-AGFIHRD-LKGSNILMQN-GLPKISDFG
  |..    ..|||..         | ....| |.     |.. |. |  ..|        |. ..  .|.  |.|||| ||  |||. . |  |..|||
QDKDHTYLYFVMEYMPRYVNDLYCGGGCELFLHLQGRRKEGRFDEERARFYAAEMQKICGCIVLALEYLHSHMGIIHRDYLKPENILLDEDGHIKLTDFG

LARKATTSQ--------------------------------------------------MIQSSSC---TPSYAAPEVLQGKQYGYKVDIWS--LGVILY
|. .  ...                                                     .. |   || | |||.|    ||. .|.||  ||...|
LCKEGMNDGEKGQQSQSNMKFHWHNKKYQKSNMDTNKCNPNNWQRNNMSQEDDTTRKKRDRTWTFCGPCTPEYMAPEIL----YGKACDWWSFGLGCLMY

RIIFGCLPFEGSS----------HTKLLKKIQ
  ..|. || | .          . .. .||.
EMLTGYPPFYGDNPQENRHPFRNPMEMFQKIM
Kinase 19068.AA CAMK 25-224 21 5.4e-56 178.58 In-house 1-360 (425) Show / Hide 
Range on Protein: 25-224
Range on HMM: 1-360/425
Sequence Identity: 21% (76 aa)

KLGSGGFSSVYLCEDE-NQ------------NKFALKKIR-------------------------------EVKERYIQQELKALMT-------IKSPYI
.||.|.|. |.||..  ..             |.| | |                                ..... ...|.. ...       .. | |
TLGRGSFGKVKLCIHKNTTGKERVHHIYTNGQKVAIKIIDKKKLKDKQNQDYSNCYKIDKSKCKHRYCWRRPKDRKNVRREIEIMKKLQGIGNKLDHPNI

VKYVE-----------NFVY---------KEYPIIIM---EYCEQG----TLDSYLKLYEG-------------GVLHEKKALNMFAYILQGIRAIHEAG
.|  |           |  |         ... ...|   |||. |     | .|..  ..             | ..|. |  .|  |..... .|. .
IKLYEVYEDPHYFKNTND-YETSKQVFTKDKHMYMVMEIMEYCSGGELFDDLFDYIVEHGCYGEEFDQFDIVERGRFTEREARRYFRQICSAVHYCHSHN

FIHRDLKGSNILM-QN-----------------GLPKISDFGLARKATT------------------------SQMIQSSSCTPSYAA-PEVLQGKQ---
 .|||||  |||. .|                 .  ||.|||.|.| .                          |. . .  ||.|.| ||||.||.   
IVHRDLKPENILLDDNNDDSDPVEHDEIFDWNNNNIKIIDFGFANKFDPGENNFMCSDYKGGEMHNQWTTPTEGQKMKTFCGTPEYMAAPEVLNGKGHCN

-----------YGYKVDIWSLGVILYRIIFGCLPFEGS-------------SHTKLLKKIQ
           ||.|.|.||.|||||    |..||.|.             .  .|..||.
MQNATDEEKPYYGPKCDMWSCGVILYIMLCGYPPFYGDCDNEICEDEWIGMNDYELFEKIM
Kinase 19068.AA NEK 20-224 29 5.8e-49 168.99 In-house 1-241 (286) Show / Hide 
Range on Protein: 20-224
Range on HMM: 1-241/286
Sequence Identity: 29% (72 aa)

YTLIQKLGSGGFSSVYLCEDENQNK------FALKKIREVK-----ERYIQQ-ELKALMT-IKSPYIVKYVENFVYKE--YPIIIMEYCE-QGTLDSY--
|..|.|.|.| |..||.... . .|      ...|||  ..     |.   | .   .   .|.|.|||| . |. ..  . .|.|||||  |.|.    
YEIIKKIGQGSFGKVYKVRRKSDGKHLVEKLYVWKKIN-MGNMSEKEKQNAQNNEVRILKQLKHPNIVKYYDSFIEEQNNCLCIVMEYCEGGGDLYQKIK

-LKLY--EGGVLHEKKALNMFAYILQGIRAIHEA-----GFIHRDLKGSNILMQ-NGL----PKISDFGLARKATTSQMIQSSS-C--TPSYAAPEVLQG
 .| .  .|  . |.. ...|. .. ... .|.        .|||.| .|| .  |.      || |||.. |   . .   .. .  || |..|||.|.
SIKKQKQKGKYFEEEQIWDWFIQMCLALKYMHDRKGPQRKILHRDIKPQNIFLTKNNNDYHNVKIGDFGIS-KVLNHTTDMAYTTQVGTPYYMSPEVCQN

KQYGYKVDIWSLGVILYRIIFGCL----PFEGS--SHTKLLKKIQ
| |..|.||||||..|| .   .|    |||..  ..  | .||.
KPYNNKSDIWSLGCVLYEMC--TLKPKHPFEAWDMNMPSLYMKIM
Kinase 19068.AA CAMKL 20-224 28 1.4e-48 153.03 In-house 1-255 (297) Show / Hide 
Range on Protein: 20-224
Range on HMM: 1-255/297
Sequence Identity: 28% (73 aa)

YTLIQKLGSGGFSSVYLCED-EN-QNKFALKKIREVKERY------------------IQQELKALMTIK---SPYIVKYVENFVYKEY------PIIIM
|.... || |.|. | |...  . . | | | |   | .                   |..| . .. ..    | |.|  | .  .|.        ..|
YRIGKTLGKGSFGKVKLATHIRTTGEKVAIKIIDKKKIWNDPWMKKNKCGQKHESDMRIRREIQIMKMLNIGKHPNIIKLYEVIETPEHDIETKKIYLVM

EYCEQGT--LDSYLKLYEG--GVLHEKKALNMFAYILQGIRAIHEAGFIHRDLKGSNILMQ-NG--LPKISDFGLARKATT-----SQMIQSSSCTPSYA
|||. |   |  |..  ..  | ..|. |  .|  |. ..  .|. | .|||.|  |||   ||    ||.|||.. . .       |.   .  .|.|.
EYCSGGEMDLFDYIVKHGHRRGRMPEHEARRYFRQIVSAVNYCHSHGIVHRDIKPENILLDENGNNNIKIIDFGFSNMYRPCIFGPGQKLKTFCGSPPYM

APEVLQG--K-QYGYKVDIWSLGVILYRIIFGCLPFEGSS-------HTKLLKKIQ
|||..||  |  .|.||||||.||||| ...| |||.. .       .. .|....
APEIFQGNNKPYDGPKVDIWSCGVILYAMVCGYLPFDDDTYNKQGKDNI-YLYWKI
Kinase 19068.AA STE 20-211 23 2.1e-46 160.46 In-house 1-268 (359) Show / Hide 
Range on Protein: 20-211
Range on HMM: 1-268/359
Sequence Identity: 23% (64 aa)

YTLIQKLGSGGFSSVYLCEDEN-----QNK-----------FALKKIR--------------------EVKERYIQQELKALMTIK--SPYIVKYVENFV
...|.|.|.|.| .||.. . .     ...           .| |...                    . ..  |..|.| ..  .  .|.||||   ..
WEGIEKIGKGAFGTVYKAMNHKNCNIHKTGEVENNGETGEIMAIKQMNLENCNNKDENQENQELENKNHEEMQQILKEIKIMKKCNHMHPNIVKYYGCYF

YK-------EYPIIIMEYCEQGTLDSYLK-LYEGG-VLH----------EKKALNMFAYILQG-IRAIHEAGFIHRDLKGSNILMQNGLPKISDFGLARK
..       ..  |.|||.. |.||. .|  |. |  |.          |.    .   ||.|    .|. . ||||.|..|||.     |..|||.. .
KEGHNHKNDDELWICMEYMDGGSLDDIIKHKYGCGKPLNHNRQHQHRFPESQIAYICRQILKGLLYYLHSHHIIHRDIKPANILL----VKLCDFGVCGQ

ATT---------------SQMIQS-SSC-TPSYAAPEVLQG------KQYGYKVDIWSLGVILYRIIFGCLPF
 |                ..  .. . . || . ||||.|.      |.|..|.||||||  .   . |. |.
LTDSMANIQSNNIIDCIETMQQKRNTFVGTP-WMAPEVIQQNGQGRDKGYDTKCDIWSLGCTIIEMATGKPPW
Kinase 19068.AA CAMK-Unique 20-275 21 1.8e-45 147.95 In-house 1-363 (363) Show / Hide 
Range on Protein: 20-275
Range on HMM: 1-363/363
Sequence Identity: 21% (80 aa)

YTLIQKLGSGGFSSVYLCED-ENQNKFALKKIRE--VK-ERYIQQ--------------------ELKALMTIKSPYIVKYVEN----FVYKE-------
|.... .|.|.|. || | | |.  |.| |...   .. ....||                    |.  . . . | |.| ..     |. ..       
YKMHRIIGHGNFGHVYECMDRETGKKWACKMVKKQTHGNKKQKQQRNFDLRYKITEKRRDMKLKREHQIWKMVDHPNIIKLYDWNNPIFCDRKYPLCDLI

--------YPIIIMEYCEQGTLDSYLKL-YE-----------------GGVLHE--KKALNMFAYILQGIRAIHEAGFIHRDLKGSNILMQNGLP-----
        |  |.||||. |.| ...    |                  |.. |    ... .. .|. .   |. . .|||||  ||. .. ..     
IKTPRALPYMYIVMEYCQGGDLFDWIQKWDEFYFNFIIKFDFNILKRCQGHFSERCWDTCFIMQCLLSAVAYMHSQDIVHRDLKLENIMVCYSFKDNNHH

------------KISDFGLARKATTSQMIQ--SSSC-TPSYAAP--------------EVLQGKQYGYKV----DIWSLGVILYRIIFGCLPFEGSSHT-
            |..||||...  ...|    .. | ||.|.||              ||. .  |....    ||||||||.|  ..||.||....   
RDFPYDWSNWHIKLCDFGLCCHYNHNKMCHMMQTMCGTPCYMAPEIVFCKNYQEMTRDEVINMQCYDQQCSPASDIWSLGVIMYYMLCGCPPFDCECEDR

-------KLLKKIQDLCQGGF-QISKAPKKKTQD---ISIGLIKLFKEIFVIDYQKRIGFKELYSNSII
       .....|   |.|..      ..|. ..   || ... . |  ...|  .|.  |||.... |
DYENHDKEIFECI---CKGDYCNF---DWKMWHGPDYISQEAKDFVKCCMTVDPDHRWSAKELLEHQWI
Kinase 19068.AA TyrKc 20-279 24 3.4e-16 39.07 SMART 1-280 (280) Show / Hide 
Range on Protein: 20-279
Range on HMM: 1-280/280
Sequence Identity: 24% (71 aa)

YTLIQKLGSGGFSSVYLCEDENQNKFALKKIREVKERYIQQELKALMTI--KSPYIVKYV-------ENFVYKEYPIIIMEYCEQGTLDSYLKLYEGGVL
 ||..|||.| |  ||...     . | |...| ... . .|.. .. .  . | ||. .       .||.| | . |.|||.. | |..||. ...  |
ITLGKKLGEGAFGEVYKGTWK--IQVAVKMLKEDAREDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPHGDLKDYLRKHRPK-L

HEKKALNMFAYILQGIRAIHEAGFIHRDLKGSNILMQNGL-PKISDFGLARKATTS-------QMIQSSS--CTPS-----YAAPEVLQGKQYGYKVDIW
  |. |..   | .| . .|. ..|||||   |.|  ...  |||||||.|. .         ... ...  .. .       |||... . .  | |.|
CMKDLLSFCWQIACGMEYLHSKNCIHRDLAARNCLVGENHTVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGKTMLPIRWMAPECINYGKFTTKSDVW

SLGVILYRII-FGCLPFEG-----SSHTKLLKKIQDLCQGGFQISKAPKKKTQD-----ISIGLIKLFKEIFVIDYQKRIGFKELYSNSIIQEQL
| || .. |  .|  | .|      | . .......    |.   . |            .  . .. |.    |  .|  |.|.       |..
SFGVCMWEIFTYGQQPYPGMIQQMMSNQEVIEYVKQ----GYRMPQPPNDY--PMSFVCCPDEMYQIMKQCWHEDPEDRPTFSEI------HECF
Kinase 19068.AA Pkinase_Tyr 20-202 27 2e-13 46.11 Pfam 1-205 (270) Show / Hide 
Range on Protein: 20-202
Range on HMM: 1-205/270
Sequence Identity: 27% (56 aa)

YTLIQKLGSGGFSSVYLCEDE-----NQNKFALKKIRE-VKERY-----IQQELKALMTI-KSPYIVKYVENFV-YKEY--PIIIMEYCEQGTLDSYLKL
 |...|||.| | .||...       .. . | |...|   ..        .|.| .... . | ||...   .  .|   ..|.|||.. | |..||. 
ITFGKKLGEGAFGEVYKGTWKGDPDNTKIPVAVKMLKEGAMHEQNCREDFMREAKIMKQLGHHPNIVRLYGVCTDQGEPNQIYIVMEYMPHGDLLDYLRK

Y--EGGVLHEKKALNMFAYILQGIRAIHEAGFIHRDLKGSNILMQ-NGLPKISDFGLARKA-----TTSQMIQSSSCTPSYAAPEVLQGKQYGYKVDIWS
   ... |  |  |.| . | .|    .. ..|||||   |.|   |.  ||.||||||         ... ... .     |||... . .  | |.||
HREDKQPLTMKDLLQMCWQIAKGMEYLESKNCIHRDLAARNCLVTENNVVKICDFGLARDIYNDDYY-YRKRGGGKLPIKWMAPECINYGKFTTKSDVWS

LGVILY
 || ..
FGVLMW