19573

Species: Tetrahymena
Alias: TTHERM_00486420, 664, 19573, 3680.m00068, PreTt19573, 59.m00211
External Links: Tetrahymena Genome Database (TGD)
Annotation:

Classification

Group: Other
Family: Ciliate-E2

Sequence

Name Sequence Type Origin Length Description Download
19573.AA Protein None 514 None Fasta, JSON
19573.kin_dom Protein Kinase Domain None 258 None Fasta, JSON
19573.NA RNA None 1545 None Fasta, JSON

Protein domain

Protein domains of 19573.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Kinase 19573.AA Ciliate-E2-Unclassified 7-264 27 5.7e-92 311.85 In-house 1-352 (352) Show / Hide
Range on Protein: 7-264
Range on HMM: 1-352/352
Sequence Identity: 27% (98 aa)

YKLLELLGTGVSGQVFLAQKKDNGCLY-----ALKFIERFYKDQQQEQYVIMQLEQEVNAIELVDSDR-----------------VIKSTECFTTEQFFV
||... .|.|  |.|...|.|... .|     . |....  | .....  ||. ..|.| ..  ...|                 ..|  .||...| . 
YKIIKQIGQGGFGKVYKCQHKKQK-QYYAMKYMKKIQIYKQKQIMNKD-EIMNEMKEMNNKKK-YHQRKYNKIMQQILLNHPHPFIVKMFYCFQDKQNIY

IVMEYCKNGDLFNYVKSKEH-----------------LNEEESI-----ELFAQILDGIKAVHSQN-LIHRDIKPENLLLDDNL---QIKIGDFGASIFY
||||||..|||..| |....                 . |....      .|||||.|..  |..|  |||||||||.|.|.|    .||| ||| |..|
IVMEYCEGGDLWQYIKKRKKQKQKGNDLFHNMKQRKIFTEQQAKYKKAKFYFAQILQGLEYLHHKNNIIHRDIKPENILFDNNGKNYYIKIIDFGISKKY

Q----------------IDNLHDNLCGTYYYM----APELENYEEYD----FSVDLWSIGCVLFFMLTGNLCNPQPDIDR----------------LIKE
|                .... .  |||..||    |||.   ..||    ...| || |..|..||.|... .... .                 |...
QQNNNCDTNQQQKMQIWKQQMMWTFCGTPNYMPQYTAPEVLQGQNYDHSKAYKCDIWSLGVILYEMLFGYYPFYDNNCEQHQQLITQWINNAYRKQLYQN

HIDKKTLNEDHNI-----CISEEVKDLIS----QMLKYSPSERISFSNILNHASF
 ..|.. .  ..       .|.|.||.|.    .|||. |..||.|. ||||  |
IKQKNIQFPKFPWQQIPKHWSPEAKDFINDLLQKMLKKNPNKRITFEQILNHPWF

Kinase 19573.AA Ciliate-E2 7-264 24 7.9e-83 281.48 In-house 1-365 (365) Show / Hide
Range on Protein: 7-264
Range on HMM: 1-365/365
Sequence Identity: 24% (91 aa)

YKLLELLGTGVSGQVFLAQKKDNGCLYALKFIERFY--------KDQQQEQYVIMQLEQEVNAIELVDSDR-----------------------VIKSTE
||.....|.|  |.|...... .....|.|.|. ..        |..... .. .. ......|. ...                         .||  |
YKFIKKIGQGNFGSVYKCKVWKVQKQFAIKIID-QKQQRQQMQEKVKIKIYAMKIMKKNQIEQIKQEIHIMREINCFYKKINEKNILEQLNHPNIIKMYE

CFT--TEQFFVIVMEYCKNGDLFNYVK-----SKEHLN------EEESIELFAQILD---------------GIKAVHSQN-LIHRDIKPENLLLDDNLQ
||   ... . .|||||. |||| | |     ......      |.| .....|||.               ...  ||.|  |||||||||.|.     
CFQEKDDNNIYLVMEYCQGGDLFDYIKNNKKKRNHEIEKDKYFTEKEIKYIMKQILQGFKTKAEFYIACIILALEYLHSKNNIIHRDIKPENILF-----

IKIGDFGASIFYQID--------------------------------NLHDNLCGTYYYMAPELENYEE---------YDFSVDLWSIGCVLFFMLTGNL
||| ||| | .|..|                                |.....|||..|||||  |...         ||...|.||.|..|..||.|..
IKIIDFGLSKKYDDDNQNRTHKQQCKWYMFKNDTSRTPGYMDQIIQQNMFNTICGTPGYMAPEILNGKKYDNQQKQKGYDYKCDIWSLGVILYEMLFGKP

-CNPQPDIDRLIKEHIDKKTLNEDH--------------NICISEEVKDLISQ----MLKYSPSERIS-FSNILNHASF
          ... .  |  ... .              .  .|.|.||||..    ||.. |..||. .. ||||  |
PF--------QQQIKQCKIDFPCPEWQKDTQCIQCKWKSWKKWSQECKDLIKKFGKRMLQKDPEKRITGWEQILNHPWF

Kinase 19573.AA S_TKc 7-264 28 2.8e-80 273.91 SMART 1-231 (231) Show / Hide
Range on Protein: 7-264
Range on HMM: 1-231/231
Sequence Identity: 28% (78 aa)

YKLLELLGTGVSGQVFLAQKKDNGCLYALKFIERFYKDQQQEQYVIMQLEQEVNAIELVDSDRVIKSTECFTTEQFFVIVMEYCKN--GDLFNYVKSKEH
|..|...| |  |.|.....|. | ..|.| |               ....|..  .  . . ..|  ..| . ... .||||| .  |||| | |.. .
YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK-------------EHIRREIQILKK-HHPNIVKLYDVFQD-DHLYMVMEYCDGDLGDLFDYIKKRGR

------LNEEESIELFAQILDGIKAVHSQNLIHRDIKPENLLLDDNLQIKIGDFGASIFYQIDNLHDNLCGTYYYMAPELENYEEYDF-SVDLWSIGCVL
      ..| .   ...||.....  ||.. ||||.||||.|||.  .|||.||| . ..      . .||| .|||||.     |.. ..| ||.||.|
HGLRFPFPE-HARFYMYQICCALEYCHSHGIIHRDLKPENILLDE--HIKICDFGLARQL------TTFCGTPWYMAPEVL---GYGKCKCDWWSCGCIL

FFMLTGNLCNPQPDIDRLIKEHIDKKTLNEDHNICISEEVKDLISQMLKYSPSERISFSNILN-------HASF
. ||.|    |  ......|                |.|.||.|...|.. |..|..   .|.       |  |
YEMLCGYPPFP--QMQMMFKKIG-------------SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF

Kinase 19573.AA AGC 7-264 20 1.6e-75 193.86 In-house 1-395 (395) Show / Hide
Range on Protein: 7-264
Range on HMM: 1-395/395
Sequence Identity: 20% (83 aa)

YKLLELLGTGVSGQVFLAQKK------DNGCLYALKFIERFY---KDQQ-QEQYVIMQ--------LEQEVNAIELVD----------SDRVIK-STECF
...| ..|.|  |.|.|..||      |.| .||.| ..  .   .... ......          . .| |  |...          .. ..|    .|
FEFLKVIGKGSFGKVYLVRKKDGCHKKDTGKYYAMKVLKKKHKIVIKKKNMVEHTMTEHWKQDQGYVWEERNILEKCNHTHNHPIKSHHPFIVKILHYSF

TTEQF--FVIVMEYCK---------NG-DLFNYVK---SKEHLNEEESIELFAQ-------ILDGIKAVHS-QNLIHRD-IKPENLLLDDNLQIKIGDFG
 ...     .||||..          | .|| . .    . ...||..   .|.       |. ..   || .. |||| .||||.|||..  ||. |||
QDKDHTYLYFVMEYMPRYVNDLYCGGGCELFLHLQGRRKEGRFDEERARFYAAEMQKICGCIVLALEYLHSHMGIIHRDYLKPENILLDEDGHIKLTDFG

ASIFYQIDN----------------------------------LHDN-----------------LCG--TYYYMAPELENYEEYDFSVDLWS--IGCVLF
 .     |.                                  ...|                 .||  |  |||||      |....| ||   ||...
LCKEGMNDGEKGQQSQSNMKFHWHNKKYQKSNMDTNKCNPNNWQRNNMSQEDDTTRKKRDRTWTFCGPCTPEYMAPEIL----YGKACDWWSFGLGCLMY

FMLTG-------N------LCNPQPDIDRLIKEHI----DKKTLNEDHN------ICISEEVKDLISQMLKYSPSERIS----------FSNILNHASF
 ||||       |       .. . ..  .|....    .| ... . .        .|.| ||||...|.  |..|.           .. | ||  |
EMLTGYPPFYGDNPQENRHPFRNPMEMFQKIMNGRYFINWKVKFPFPEDPQFPEDRWFSPEAKDLIKKLLCKDPEKRLGCGGNDFGDKGAEEIKNHPWF

Kinase 19573.AA CAMK 12-264 20 3.7e-75 241.43 In-house 1-425 (425) Show / Hide
Range on Protein: 12-264
Range on HMM: 1-425/425
Sequence Identity: 20% (89 aa)

LLGTGVSGQVFLAQKK-DNG-----------CLYALKFIERFYKDQQQ----------------------EQYVIMQLEQEVNAIEL-------VDSDRV
 ||.|  |.|.|.. | ..|             .| |.|..   . .|                      ...   ....|..   .       .|   .
TLGRGSFGKVKLCIHKNTTGKERVHHIYTNGQKVAIKIIDKKKLKDKQNQDYSNCYKIDKSKCKHRYCWRRPKDRKNVRREIEIMKKLQGIGNKLDHPNI

IKSTECFTT-------------------EQFFVIVM---EYCKNG----DLFNYVKSKEH---------------LNEEESIELFAQILDGIKAVHSQNL
||  | . .                   ......||   ||| .|    |||.|......               ..|.|   .| ||.....  ||.| 
IKLYEVYEDPHYFKNTNDYETSKQVFTKDKHMYMVMEIMEYCSGGELFDDLFDYIVEHGCYGEEFDQFDIVERGRFTEREARRYFRQICSAVHYCHSHNI

IHRDIKPENLLLDDN-----------------LQIKIGDFGASIFYQI------------------------DNLHDNLCGTYYYMA-PELENY------
.|||.||||.|||||                  .||| ||| .....                         . .    ||| .||| ||. |.      
VHRDLKPENILLDDNNDDSDPVEHDEIFDWNNNNIKIIDFGFANKFDPGENNFMCSDYKGGEMHNQWTTPTEGQKMKTFCGTPEYMAAPEVLNGKGHCNM

--------EEYDFSVDLWSIGCVLFFMLTGNLCNPQPD------------IDRLIKEHIDKKTLN-EDH-------------NICISEE--------VKD
        . |....| ||.|..|..||.| .    ..             |. ..| | |   . ...               .||.|        .||
QNATDEEKPYYGPKCDMWSCGVILYIMLCGYPPFYGDCDNEICEDEWIGMNDYELFEKIMKGKYDFPPPYFSPISCNYGPEWWDDISDEFHHFVSQECKD

LISQMLKYSPSERISFSNILNHASF
||..||.. |..|.. . .|||  .
LIRKMLQVDPEKRMTIEQCLNHPWM

Kinase 19573.AA CAMKL 7-264 27 1.5e-73 234.03 In-house 1-297 (297) Show / Hide
Range on Protein: 7-264
Range on HMM: 1-297/297
Sequence Identity: 27% (84 aa)

YKLLELLGTGVSGQVFLAQK-KDNGCLYALKFIERFYKDQQQEQYVIMQ------------LEQEVNAIELVDSDR----VIKSTECFTTEQF------F
|.... ||.|  |.| ||.  . .|. .| |.|.   |.  ..  ....            ...|..  ....  .    .||  |...|...      .
YRIGKTLGKGSFGKVKLATHIRTTGEKVAIKIID---KKKIWNDPWMKKNKCGQKHESDMRIRREIQIMKMLN-IGKHPNIIKLYEVIETPEHDIETKKI

VIVMEYCKNGD--LFNYVKSKEH----LNEEESIELFAQILDGIKAVHSQNLIHRDIKPENLLLDDNL--QIKIGDFGASIFYQ-I----DNLHDNLCGT
..||||| .|.  ||.|.....|    . |.|   .| ||.....  ||.. .||||||||.|||.|   .||| ||| |..|. .    ... .  ||.
YLVMEYCSGGEMDLFDYIVKHGHRRGRMPEHEARRYFRQIVSAVNYCHSHGIVHRDIKPENILLDENGNNNIKIIDFGFSNMYRPCIFGPGQKLKTFCGS

YYYMAPELENY--EEYD-FSVDLWSIGCVLFFMLTGNLCNPQPDI------DRLIKEHIDKKTLNED-HNICISEEVKDLISQMLKYSPSERISFSNILN
. |||||. .   ..|| . || ||.| .|..|..|.|   ....      .   ........  .. . . .| ...|||..||.  |..|..  .|.|
PPYMAPEIFQGNNKPYDGPKVDIWSCGVILYAMVCGYLPFDDDTYNKQGKDNI-YLYWKIMCG-YYPPIWYHVS-DCRDLIRKMLQVNPEKRPTIHQIMN

HASF
|  .
HPWM

Kinase 19573.AA Pkinase 7-264 28 3.5e-72 250.92 Pfam 1-293 (293) Show / Hide
Range on Protein: 7-264
Range on HMM: 1-293/293
Sequence Identity: 28% (85 aa)

YKLLELLGTGVSGQVFLAQKKDNGCLYALKFIERFYKDQQQEQYVIMQLEQEVNAIELVDSDRVIKSTECFTTEQFFVIVMEYCKNG----DLFNYVK--
|.... .| | .|.|.....|..|...|.| |..  .. ...|. .    .|.     .... ...  ..|....   .||||| .|    ||| |..  
YHIGRKIGSGSFGCVYKCHHKGTGKIVAVKIIKKRHEKSWKDQTHRRL--SEIQIMKRLNHPNIVRLYDWFEDKDHIYMVMEYCEGGLYVMDLFDYISTW

SKEHL--NEEESIELFAQILDGIKAVHSQNLIHRDIKPENLLLDDNLQI----KIGDFGASIF--YQIDNLHDNLCGTYYYMAPELEN-YEEYDFSVDLW
..  .   |.| .  . ||| |..  ||.. ||||.||||.|.|.| .|    ||.||| . .  |  .   . .|||..|||||. . ...|. .|| |
RHGCFYFSEWECKFYMYQILRGLEYCHSMGIIHRDLKPENILIDNNGHIDACVKICDFGLAKQFDY-NNS-MTTFCGTPWYMAPEVIRGGQYYGPKVDMW

SIGCVLFFMLTGNLCNPQP------DIDRLIKEHID-KKTLNEDHNICIS-----------------EEVKDLISQMLKYSPSERISFSNILNHASF
|.||.|. ||.|..  |.       | . .|..  . .   ...  ..||                 || ||.|. .|.. |..|...  ||.|  |
SCGCILYEMLCGRPPFPGHCWHDNHDQMQMICRIMGPPLHFDWPWWCSISYFFFRHWHFHWTFHNWSEECKDFIKWCLCKDPKKRPTAEQILQHPWF

Kinase 19573.AA ULK 7-264 28 8e-72 244.92 In-house 1-324 (324) Show / Hide
Range on Protein: 7-264
Range on HMM: 1-324/324
Sequence Identity: 28% (92 aa)

YKLLELLGTGVSG-QVFLAQKKDN---GCLYALKFIERF-YKDQQQE---QYVIMQLEQEVNAIELVD---SDR--VIKSTECFTTE--QFFVIVMEYCK
| | . || |  | .|. . .|..   . ..| | |...  .....|   || . .|..|.. .   .   .    ..|  ..| |    .. |.|||| 
YCLNHCLGKGSFGVKVYKGRNKKTNTQNQYVACKMIDKKKMNKKKNEQEGQYMWQLLKNEIQIMKKLKELKHPNHHIVKLYDWFETSNHNNIYIIMEYCN

NGDLFNYVKSKEH---------LNEEESIELFAQILDGIKAVHSQNLIHRDIKPENLLLDDNL------------QIKIGDFGASIFYQIDNLHDNLC--
 |||..| | . .         |.|.| |. | ||. | |. |..| |||||||.|.|. ..             ..||.||| . . . .|. ...|  
GGDLEQYIKKNKKLPETEEKKRLSEQEAIQFFKQICNGFKELHKHNIIHRDIKPQNILIHNGQPKTDSKKVHPNGVLKIADFGFAKHVDNNNMEQQMCQT

--------GTYYYMAPELENYE----EYD-FSVDLWSIGCVLFFMLTGNLC---NPQPDID----RLIKEH------IDKKTLNED---HNICISEEVKD
        || .||||.. . .    .|. . .|.||.||... ||.|      .   | .    .||.        | .. .. .    .. ||.|.||
CVNEKRIKGTPLYMAPQILQGQGEQKPYYDYKCDIWSLGCIFYEMLYGKYPFFSW-FNDQYLYIQKLINNGKEQQIYIKNQPIQFPKPPKDPKISPECKD

LISQMLKYSPSERISFSNILNHASF
||..||.| ...|||.  |.||  |
LIRRMLQYDEKDRISWEEIFNHPWF

Kinase 19573.AA ULK 7-264 29 2.7e-68 233.21 In-house 1-329 (329) Show / Hide
Range on Protein: 7-264
Range on HMM: 1-329/329
Sequence Identity: 29% (96 aa)

YKLLELLGTGVSGQVFLAQKKDN----GCLYALKFIERFYKDQQQE----QYVIMQLEQEVNAIELVDSDR--------VIKSTECFTTEQF--FVIVME
| | . || |  |.|. . .|..    . ..| | |......|..     || . .|..|.  .   .|          ..|  ..| | ..  . |.||
YCLNHCLGKGSFGKVYKGRNKKTKDYVNEKVACKMIDKQKMNQKNNEQEGQYMWQLLKNEIKIMKKLKSPNRHKNHHPNIVKLYDWFETSNHNNIYIIME

YCKNGDLFNYVKSKEH----------LNEEESIELFAQILDGIKAVHSQNLIHRDIKPENLLLDDNL------------QIKIGDFGASIFYQIDN----
||  |||..| | . .          |.|.| |. | ||| | |. |..| |||||||.| |....             ..||.||| . . . ||    
YCNGGDLEQYIKKNKKLPEDTEEKKRLSEQEAIQFFKQILNGFKELHKHNIIHRDIKPQNILIHNGQPKTDSKKVHPNGVLKIADFGFAKHVDNDNMEQQ

-LHDNL-----CGTYYYMAPELENYE----EYD-FSVDLWSIGCVLFFMLTGNLC---NPQPDID-----RLIKE------HIDKKTLNED---HNICIS
 ..  .     ||| .||||.. . .    .|. . .|.||.||... ||.|      .   | .     .||.        |.|. |. .    .. ||
MMMTCVNEKRLCGTPLYMAPQILQGQGEQKPYYDYKCDIWSLGCIFYEMLYGKPPFYAW-FNDQYLQIIQKLINNPPPWPQQIKKQPLQFPKDGNDPQIS

EEVKDLISQMLKYSPSERISFSNILNHASF
.|.||||..||.| ...|||.  ..||  |
PECKDLIRRMLQYDEKDRISWEELFNHPWF

Kinase 19573.AA Ciliate-E2a 7-203 32 5.5e-56 163.3 In-house 1-212 (275) Show / Hide
Range on Protein: 7-203
Range on HMM: 1-212/275
Sequence Identity: 32% (70 aa)

YKLLELLGTGVSGQVFLAQKKDNGCLYALKFIERFYKDQQQEQYVIMQLEQEVNAIELVDSDRVIKSTECFTTEQFFVIVMEYCKNGDLFNYVKSKEHLN
||.. ..|.|  |.|.|||.|..|  .| | ..... .| ...    ....|.| .  .| . .||  | . .|. . .|||||. |.|... | .  ..
YKFIKKIGKGNFGSVYLAQHKQTGKQFAMKKFIKKMYQQKKGK---EYFMNEINIMRQLDHPNIIKLYEVYEDENNYYLVMEYCEGGELYDKIKQCKRFF

EE--ESIELFAQIL-DGIKAVHSQNLIHRDIKPENLLLD---DN----LQIKIGDFGASIFY--QIDNLHDNLCGTYYYMAPELENYEE------YDFSV
||  |  ..  |.| .|.  .|..| .|||.||||.|..    |    ..||| ||| . |.   . .     ||| .|.|||. |..|      || ..
EEIQEICDIMQQLLWQGLHYMHQRNIMHRDLKPENILFKNCSKNSIQNSDIKIIDFGLATFIDKDEKKYMFQKCGTPGYVAPEVLNNKEVLKHKQYDTKC

DLWSIGCVLFFMLTG
|.||.|......|.|
DMWSCGVIFYILLCG

Kinase 19573.AA CAMK1 7-203 32 4.2e-54 155.64 In-house 1-212 (276) Show / Hide
Range on Protein: 7-203
Range on HMM: 1-212/276
Sequence Identity: 32% (69 aa)

YKLLELLGTGVSGQVFLAQKKDN---GCLYALKFIERFYKDQQQEQYVI--MQLEQEVNAIELV---DSDRVIKSTECFTTEQFFVIVMEYCKNGDLFNY
|.. . .|.|  ..|.|...|..   |  ||.| |.   |.. .. ..   ..||.|..    |   |   .||  | . .. .| .|||....|.||  
YEFGKEIGRGAFSEVYLCTHKETQTNGKQYAIKCIDK--KKFMKKKDMQKQEALENEIEIMKKVSKIDHPNIIKFYEWYESDNHFYLVMELVTGGELFDR

VKSKEHLNEEESIELFAQILDGIKAVHSQNLIHRDIKPENLLLDDN---LQIK--IGDFGASIFYQIDN-LHDNLCGTYYYMAPELENY---EEYDFSVD
.  |.. .|..  ..  |||. ..  ||..  |||.||||||. |.    .||  | ||| | ..  |. |    ||| .|.|||  ..   . || ..|
IVEKGNYTEKDARHIMKQILSAVEYMHSKGIVHRDLKPENLLYYDKDEDSKIKRSIADFGLSKIFDHDENLMKTACGTPGYVAPEVLECKKDKPYDKACD

LWSIGCVLFFMLTG
.||||......|.|
MWSIGVITYILLCG

Kinase 19573.AA MARK 79-205 44 3.7e-49 158.91 In-house 72-204 (262) Show / Hide
Range on Protein: 79-205
Range on HMM: 72-204/262
Sequence Identity: 44% (59 aa)

TEQF-FVIVMEYCKNGDLFNYVKSK--EHLNEEESIELFAQILDGIKAVHSQNLIHRDIKPENLLLDDNL--QIKIGDFGASIFYQIDNLHDNLCGTYYY
|||  ....|||. .|.|..|.|..   .| |||   .| ||. ...  ||.| .||||||||.|.|.|   .||| ||| ||  . ... .  |||. |
TEQHQIYLIMEYASGGELYDYIKAHPNGRLHEEEARRIFRQIVSAVNYCHSKNIVHRDIKPENILIDENGNHNIKIIDFGFSICIPPGQKLNTFCGTPPY

MAPELENYEEYD-FSVDLWSIGCVLFFMLTGNL
||||. ....|| . || || | ||.||..|..
MAPEIFLKKPYDGPKVDIWSLGVVLYFMVCGYF

Kinase 19573.AA TyrKc 7-264 21 1.9e-15 26.93 SMART 1-280 (280) Show / Hide
Range on Protein: 7-264
Range on HMM: 1-280/280
Sequence Identity: 21% (63 aa)

YKLLELLGTGVSGQVFLAQKKDNGCLYALKFIERFYKDQQQEQYVIMQLEQEVNAIELV--DSDRVIKSTECFTTE-------QFFVIVMEYCKNGDLFN
 .|.. || |  |.|.... |      | | .             .. . .| .    .  . . ...   . |..       .   |||||...||| .
ITLGKKLGEGAFGEVYKGTWK---IQVAVKMLKEDA---------REDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPHGDLKD

YVKSKEH-LNEEESIELFAQILDGIKAVHSQNLIHRDIKPENLLLDDNLQIKIGDFGASIFYQID-------NLHD-----NLC--GTYYYMAPELENYE
| ..... |. .. ..   || .|    ||.|.||||.   | |...|...||.||| | .   |          .     .      .  ||||  || 
YLRKHRPKLCMKDLLSFCWQIACGMEYLHSKNCIHRDLAARNCLVGENHTVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGKTMLPIRWMAPECINYG

EYDFSVDLWSIGCVLFFMLTGNLCNPQP-----DIDRLIKEHIDKKTLNEDHNI-------CISEEVKDLISQMLKYSPSERISFSNILNHASF
.. .  | || | ... ..|     .         .. . |....    .           | ..|. ....|  .. |..| .||.|  |  |
KFTTKSDVWSFGVCMWEIFTYGQQPYPGMIQQMMSNQEVIEYVKQGYRMPQPPNDYPMSFVCCPDEMYQIMKQCWHEDPEDRPTFSEI--HECF

Kinase 19573.AA Ciliate-E2a 232-264 42 3e-10 26.38 In-house 243-275 (275) Show / Hide
Range on Protein: 232-264
Range on HMM: 243-275/275
Sequence Identity: 42% (14 aa)

CISEEVKDLISQMLKYSPSERISFSNILNHASF
..| | |||...||.. |..||.   .|||  |
KCSKECKDLMKKMLEKDPKKRITAQQALNHPWF

Kinase 19573.AA Pkinase_Tyr 85-153 38 5.6e-09 31.02 Pfam 84-156 (270) Show / Hide
Range on Protein: 85-153
Range on HMM: 84-156/270
Sequence Identity: 38% (28 aa)

IVMEYCKNGDLFNYVKS----KEHLNEEESIELFAQILDGIKAVHSQNLIHRDIKPENLLLDDNLQIKIGDFG
|||||...||| .| ..    |..|. .. ..  .|| .|    .|.|.||||.   | |...|...||.|||
IVMEYMPHGDLLDYLRKHREDKQPLTMKDLLQMCWQIAKGMEYLESKNCIHRDLAARNCLVTENNVVKICDFG

Kinase 19573.AA CAMK1 233-264 36 6.9e-09 21.91 In-house 244-276 (276) Show / Hide
Range on Protein: 233-264
Range on HMM: 244-276/276
Sequence Identity: 36% (12 aa)

ISEE-VKDLISQMLKYSPSERISFSNILNHASF
||.. .||.|..||.  |..|.... .|||  .
ISDQEAKDFIKHMLEVDPKKRYTCEQCLNHPWI

Kinase 19573.AA MARK 7-49 34 2.2e-07 20.36 In-house 1-44 (262) Show / Hide
Range on Protein: 7-49
Range on HMM: 1-44/262
Sequence Identity: 34% (15 aa)

YKLLELLGTGVSGQVFLAQKKDNGCLYALKFIERFYKDQ-QQEQ
||.|  .|.|  ..| ||. |  |  .|.|..|.| ..  |. .
YKMLKTIGHGSYAKVKLACHKHTGRKVAIKIYEKFKLNDPQWMK

Kinase 19573.AA MARK 233-264 31 2e-06 17.1 In-house 231-262 (262) Show / Hide
Range on Protein: 233-264
Range on HMM: 231-262/262
Sequence Identity: 31% (10 aa)

ISEEVKDLISQMLKYSPSERISFSNILNHASF
.| | ..||...|.  |.||.. ..|..|  .
VSKECRNLIQRLLTVNPEERPTIEEIMKHPWM

Kinase 19573.AA Pkinase_Tyr 234-264 35 8.080803 0.01 Pfam 242-270 (270) Show / Hide
Range on Protein: 234-264
Range on HMM: 242-270/270
Sequence Identity: 35% (11 aa)

SEEVKDLISQMLKYSPSERISFSNILNHASF
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PDEIYDLMKQCWHYDPEDRPTFSEI--HEQL